Motif ID: Hoxb7
Z-value: 3.443
Transcription factors associated with Hoxb7:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Hoxb7 | ENSMUSG00000038721.8 | Hoxb7 |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
28.3 | 84.9 | GO:0007521 | muscle cell fate determination(GO:0007521) cellular response to parathyroid hormone stimulus(GO:0071374) positive regulation of macrophage apoptotic process(GO:2000111) |
12.3 | 73.9 | GO:1903056 | positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056) |
12.3 | 49.3 | GO:0099566 | regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566) |
9.5 | 76.2 | GO:0060164 | regulation of timing of neuron differentiation(GO:0060164) |
8.7 | 78.4 | GO:0035887 | aortic smooth muscle cell differentiation(GO:0035887) |
8.6 | 25.8 | GO:0001928 | regulation of exocyst assembly(GO:0001928) |
8.1 | 24.3 | GO:0098923 | retrograde trans-synaptic signaling by soluble gas(GO:0098923) |
7.8 | 54.8 | GO:0019532 | oxalate transport(GO:0019532) |
7.8 | 23.4 | GO:0051892 | negative regulation of cardioblast differentiation(GO:0051892) |
7.7 | 30.8 | GO:0090126 | protein complex assembly involved in synapse maturation(GO:0090126) |
7.7 | 100.0 | GO:1901898 | negative regulation of relaxation of cardiac muscle(GO:1901898) |
7.3 | 36.7 | GO:0042636 | negative regulation of hair cycle(GO:0042636) negative regulation of hair follicle development(GO:0051799) positive regulation of ovulation(GO:0060279) |
7.3 | 22.0 | GO:0003345 | proepicardium cell migration involved in pericardium morphogenesis(GO:0003345) |
7.1 | 85.2 | GO:1900383 | regulation of synaptic plasticity by receptor localization to synapse(GO:1900383) |
6.6 | 59.4 | GO:0036371 | protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371) |
5.9 | 52.8 | GO:0071420 | cellular response to histamine(GO:0071420) |
5.7 | 39.9 | GO:0005513 | detection of calcium ion(GO:0005513) |
5.7 | 22.8 | GO:0001550 | ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) |
5.7 | 28.4 | GO:0046684 | response to pyrethroid(GO:0046684) |
5.5 | 16.6 | GO:0042663 | regulation of endodermal cell fate specification(GO:0042663) |
5.4 | 32.2 | GO:0072318 | clathrin coat disassembly(GO:0072318) |
5.2 | 15.7 | GO:0007525 | somatic muscle development(GO:0007525) |
5.2 | 15.7 | GO:0098735 | positive regulation of the force of heart contraction(GO:0098735) |
5.2 | 20.8 | GO:0048686 | regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690) |
5.2 | 15.5 | GO:0017085 | response to insecticide(GO:0017085) |
5.0 | 55.2 | GO:0010650 | positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827) |
5.0 | 14.9 | GO:1903538 | meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538) |
4.9 | 14.7 | GO:0002182 | cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248) |
4.6 | 32.4 | GO:1900042 | positive regulation of interleukin-2 secretion(GO:1900042) |
4.3 | 12.8 | GO:0006597 | spermine biosynthetic process(GO:0006597) |
4.0 | 166.4 | GO:0006376 | mRNA splice site selection(GO:0006376) |
3.8 | 11.5 | GO:0060478 | acrosomal vesicle exocytosis(GO:0060478) |
3.8 | 56.9 | GO:1902004 | positive regulation of beta-amyloid formation(GO:1902004) |
3.7 | 18.6 | GO:0007256 | activation of JNKK activity(GO:0007256) |
3.7 | 14.9 | GO:0099552 | trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553) |
3.6 | 10.9 | GO:0009826 | unidimensional cell growth(GO:0009826) susceptibility to natural killer cell mediated cytotoxicity(GO:0042271) |
3.6 | 14.5 | GO:2000795 | negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795) |
3.5 | 35.3 | GO:0061470 | interleukin-21 production(GO:0032625) T follicular helper cell differentiation(GO:0061470) interleukin-21 secretion(GO:0072619) |
3.5 | 10.5 | GO:0010838 | positive regulation of keratinocyte proliferation(GO:0010838) |
3.5 | 38.4 | GO:0060501 | positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501) |
3.4 | 17.0 | GO:0043314 | negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313) |
3.4 | 47.4 | GO:0007213 | G-protein coupled acetylcholine receptor signaling pathway(GO:0007213) |
3.4 | 13.4 | GO:0014846 | esophagus smooth muscle contraction(GO:0014846) |
3.3 | 50.1 | GO:0021902 | commitment of neuronal cell to specific neuron type in forebrain(GO:0021902) |
3.2 | 12.8 | GO:0097118 | neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118) |
3.1 | 9.4 | GO:0043379 | memory T cell differentiation(GO:0043379) |
3.1 | 40.9 | GO:0070842 | aggresome assembly(GO:0070842) |
3.1 | 15.6 | GO:1901843 | positive regulation of high voltage-gated calcium channel activity(GO:1901843) |
3.1 | 24.7 | GO:0071372 | cellular response to follicle-stimulating hormone stimulus(GO:0071372) |
3.1 | 12.2 | GO:0003105 | negative regulation of glomerular filtration(GO:0003105) |
3.0 | 12.2 | GO:2000481 | positive regulation of cAMP-dependent protein kinase activity(GO:2000481) |
3.0 | 11.9 | GO:0010808 | positive regulation of synaptic vesicle priming(GO:0010808) |
2.9 | 8.7 | GO:0050915 | sensory perception of sour taste(GO:0050915) |
2.9 | 2.9 | GO:0043696 | dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697) |
2.9 | 2.9 | GO:0097324 | melanocyte migration(GO:0097324) |
2.9 | 14.3 | GO:0006543 | glutamine catabolic process(GO:0006543) |
2.8 | 2.8 | GO:0007113 | endomitotic cell cycle(GO:0007113) |
2.8 | 13.9 | GO:1903566 | positive regulation of protein localization to cilium(GO:1903566) |
2.7 | 13.6 | GO:2000301 | negative regulation of synaptic vesicle exocytosis(GO:2000301) |
2.7 | 8.2 | GO:0097401 | synaptic vesicle lumen acidification(GO:0097401) |
2.7 | 18.9 | GO:0090074 | negative regulation of protein homodimerization activity(GO:0090074) |
2.6 | 2.6 | GO:0072204 | cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204) |
2.6 | 7.9 | GO:0001830 | trophectodermal cell fate commitment(GO:0001830) |
2.6 | 7.8 | GO:0001543 | ovarian follicle rupture(GO:0001543) |
2.6 | 127.6 | GO:0007157 | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157) |
2.6 | 5.2 | GO:2000790 | regulation of mesenchymal cell proliferation involved in lung development(GO:2000790) negative regulation of mesenchymal cell proliferation involved in lung development(GO:2000791) |
2.6 | 12.9 | GO:0035063 | nuclear speck organization(GO:0035063) |
2.5 | 10.2 | GO:0038128 | ERBB2 signaling pathway(GO:0038128) |
2.5 | 15.1 | GO:0030643 | cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502) |
2.3 | 32.8 | GO:0045161 | neuronal ion channel clustering(GO:0045161) |
2.3 | 14.0 | GO:0086018 | SA node cell action potential(GO:0086015) SA node cell to atrial cardiac muscle cell signalling(GO:0086018) SA node cell to atrial cardiac muscle cell communication(GO:0086070) |
2.3 | 13.9 | GO:1903847 | regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849) |
2.3 | 11.5 | GO:1903026 | negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026) positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378) |
2.2 | 20.1 | GO:0010587 | miRNA catabolic process(GO:0010587) |
2.2 | 13.4 | GO:0060012 | synaptic transmission, glycinergic(GO:0060012) |
2.2 | 17.8 | GO:2000766 | negative regulation of cytoplasmic translation(GO:2000766) |
2.2 | 6.6 | GO:0015882 | L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904) |
2.2 | 8.7 | GO:1903215 | negative regulation of protein targeting to mitochondrion(GO:1903215) |
2.2 | 28.1 | GO:0048672 | positive regulation of collateral sprouting(GO:0048672) |
2.2 | 49.5 | GO:0008090 | retrograde axonal transport(GO:0008090) |
2.1 | 6.3 | GO:1904978 | regulation of endosome organization(GO:1904978) positive regulation of endosome organization(GO:1904980) |
2.1 | 6.2 | GO:0098912 | membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912) |
2.0 | 81.7 | GO:0007026 | negative regulation of microtubule depolymerization(GO:0007026) |
2.0 | 35.2 | GO:0046069 | cGMP catabolic process(GO:0046069) |
1.9 | 13.6 | GO:0014819 | regulation of skeletal muscle contraction(GO:0014819) |
1.9 | 13.2 | GO:0046549 | retinal cone cell development(GO:0046549) |
1.9 | 5.6 | GO:1903896 | positive regulation of IRE1-mediated unfolded protein response(GO:1903896) |
1.9 | 7.5 | GO:1901475 | pyruvate transmembrane transport(GO:1901475) |
1.8 | 7.2 | GO:0033194 | response to hydroperoxide(GO:0033194) |
1.7 | 7.0 | GO:0006848 | pyruvate transport(GO:0006848) |
1.7 | 11.9 | GO:1904017 | response to Thyroglobulin triiodothyronine(GO:1904016) cellular response to Thyroglobulin triiodothyronine(GO:1904017) |
1.7 | 10.1 | GO:0090073 | positive regulation of protein homodimerization activity(GO:0090073) |
1.7 | 8.3 | GO:0048245 | eosinophil chemotaxis(GO:0048245) |
1.6 | 11.4 | GO:1902856 | negative regulation of nonmotile primary cilium assembly(GO:1902856) |
1.6 | 3.3 | GO:0003289 | septum primum development(GO:0003284) atrial septum primum morphogenesis(GO:0003289) |
1.6 | 14.5 | GO:0006682 | galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) |
1.6 | 9.5 | GO:0015015 | heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015) |
1.6 | 7.9 | GO:0033762 | response to glucagon(GO:0033762) |
1.6 | 3.2 | GO:0043490 | malate-aspartate shuttle(GO:0043490) |
1.6 | 6.3 | GO:0099550 | trans-synaptic signalling, modulating synaptic transmission(GO:0099550) |
1.6 | 1.6 | GO:2001214 | positive regulation of vasculogenesis(GO:2001214) |
1.6 | 26.6 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
1.5 | 6.2 | GO:0097494 | positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944) regulation of vesicle size(GO:0097494) |
1.5 | 7.6 | GO:0015692 | vanadium ion transport(GO:0015676) lead ion transport(GO:0015692) |
1.5 | 4.5 | GO:0035864 | response to potassium ion(GO:0035864) cellular response to potassium ion(GO:0035865) |
1.5 | 16.3 | GO:0018230 | peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231) |
1.5 | 8.8 | GO:0051694 | pointed-end actin filament capping(GO:0051694) |
1.5 | 5.8 | GO:0014005 | microglia differentiation(GO:0014004) microglia development(GO:0014005) |
1.4 | 5.7 | GO:0007171 | activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171) |
1.4 | 4.2 | GO:0044028 | DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029) |
1.4 | 4.1 | GO:0050925 | negative regulation of negative chemotaxis(GO:0050925) |
1.4 | 4.1 | GO:0045200 | establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) |
1.4 | 10.8 | GO:0019227 | neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870) |
1.3 | 9.4 | GO:0060267 | positive regulation of respiratory burst(GO:0060267) |
1.3 | 10.7 | GO:0032926 | negative regulation of activin receptor signaling pathway(GO:0032926) |
1.3 | 18.8 | GO:0048755 | branching morphogenesis of a nerve(GO:0048755) |
1.3 | 68.1 | GO:0034605 | cellular response to heat(GO:0034605) |
1.3 | 3.9 | GO:0019805 | quinolinate biosynthetic process(GO:0019805) |
1.3 | 11.6 | GO:0097119 | postsynaptic density protein 95 clustering(GO:0097119) |
1.3 | 31.0 | GO:0002091 | negative regulation of receptor internalization(GO:0002091) |
1.2 | 3.7 | GO:0007262 | STAT protein import into nucleus(GO:0007262) |
1.2 | 74.9 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
1.2 | 7.3 | GO:0071442 | positive regulation of histone H3-K14 acetylation(GO:0071442) |
1.2 | 15.9 | GO:2001256 | regulation of store-operated calcium entry(GO:2001256) |
1.2 | 29.3 | GO:0007097 | nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023) |
1.2 | 4.7 | GO:2000821 | regulation of grooming behavior(GO:2000821) |
1.2 | 11.7 | GO:0019065 | receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509) |
1.2 | 4.6 | GO:1901301 | regulation of cargo loading into COPII-coated vesicle(GO:1901301) |
1.2 | 6.9 | GO:0015014 | heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014) |
1.2 | 3.5 | GO:0060060 | post-embryonic retina morphogenesis in camera-type eye(GO:0060060) |
1.1 | 18.2 | GO:0051447 | negative regulation of meiotic cell cycle(GO:0051447) |
1.1 | 6.8 | GO:0098964 | dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964) |
1.1 | 7.8 | GO:0016185 | synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185) |
1.1 | 5.5 | GO:0044314 | protein K27-linked ubiquitination(GO:0044314) |
1.1 | 10.9 | GO:1900103 | positive regulation of endoplasmic reticulum unfolded protein response(GO:1900103) |
1.1 | 6.5 | GO:1990573 | potassium ion import across plasma membrane(GO:1990573) |
1.1 | 4.3 | GO:0060178 | regulation of exocyst localization(GO:0060178) |
1.0 | 2.1 | GO:0099527 | postsynapse to nucleus signaling pathway(GO:0099527) |
1.0 | 5.1 | GO:1905150 | regulation of voltage-gated sodium channel activity(GO:1905150) |
1.0 | 12.3 | GO:0098989 | NMDA selective glutamate receptor signaling pathway(GO:0098989) |
1.0 | 4.1 | GO:0021502 | neural fold elevation formation(GO:0021502) |
1.0 | 7.0 | GO:2001269 | positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269) |
1.0 | 8.0 | GO:2000096 | positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096) |
1.0 | 2.0 | GO:0070343 | white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350) |
1.0 | 18.3 | GO:2001224 | positive regulation of neuron migration(GO:2001224) |
1.0 | 1.9 | GO:0010968 | regulation of microtubule nucleation(GO:0010968) |
0.9 | 2.8 | GO:1903025 | regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025) |
0.9 | 4.5 | GO:0016198 | axon choice point recognition(GO:0016198) |
0.9 | 0.9 | GO:0060527 | prostate glandular acinus morphogenesis(GO:0060526) prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis(GO:0060527) |
0.9 | 14.3 | GO:2000251 | positive regulation of actin cytoskeleton reorganization(GO:2000251) |
0.9 | 23.8 | GO:0043666 | regulation of phosphoprotein phosphatase activity(GO:0043666) |
0.8 | 2.5 | GO:0036500 | ATF6-mediated unfolded protein response(GO:0036500) |
0.8 | 2.5 | GO:0042264 | peptidyl-aspartic acid hydroxylation(GO:0042264) |
0.8 | 2.5 | GO:1901421 | positive regulation of response to alcohol(GO:1901421) |
0.8 | 4.1 | GO:0070966 | nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966) |
0.8 | 3.3 | GO:0090261 | positive regulation of inclusion body assembly(GO:0090261) |
0.8 | 21.0 | GO:0032011 | ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012) |
0.8 | 24.8 | GO:0010614 | negative regulation of cardiac muscle hypertrophy(GO:0010614) |
0.8 | 7.1 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
0.8 | 42.7 | GO:0051965 | positive regulation of synapse assembly(GO:0051965) |
0.8 | 4.6 | GO:0035331 | negative regulation of hippo signaling(GO:0035331) |
0.8 | 1.5 | GO:0016056 | rhodopsin mediated signaling pathway(GO:0016056) |
0.7 | 4.4 | GO:0098703 | calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035) |
0.7 | 9.5 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
0.7 | 3.6 | GO:1900095 | regulation of dosage compensation by inactivation of X chromosome(GO:1900095) |
0.7 | 4.9 | GO:0018344 | protein geranylgeranylation(GO:0018344) |
0.7 | 2.1 | GO:1902260 | negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817) |
0.7 | 15.9 | GO:0021952 | central nervous system projection neuron axonogenesis(GO:0021952) |
0.7 | 1.4 | GO:0051794 | regulation of catagen(GO:0051794) positive regulation of catagen(GO:0051795) |
0.7 | 2.0 | GO:0045409 | negative regulation of interleukin-6 biosynthetic process(GO:0045409) |
0.7 | 2.7 | GO:1902268 | negative regulation of polyamine transmembrane transport(GO:1902268) |
0.7 | 4.6 | GO:2000270 | negative regulation of fibroblast apoptotic process(GO:2000270) |
0.7 | 2.0 | GO:2000393 | negative regulation of lamellipodium organization(GO:1902744) negative regulation of lamellipodium morphogenesis(GO:2000393) |
0.6 | 1.9 | GO:0071649 | negative regulation of acute inflammatory response to antigenic stimulus(GO:0002865) regulation of chemokine (C-C motif) ligand 5 production(GO:0071649) |
0.6 | 3.8 | GO:1901164 | negative regulation of trophoblast cell migration(GO:1901164) |
0.6 | 2.6 | GO:0071985 | multivesicular body sorting pathway(GO:0071985) |
0.6 | 2.6 | GO:0048631 | regulation of skeletal muscle tissue growth(GO:0048631) |
0.6 | 10.9 | GO:0001553 | luteinization(GO:0001553) |
0.6 | 4.5 | GO:0030035 | microspike assembly(GO:0030035) |
0.6 | 5.0 | GO:1902259 | regulation of delayed rectifier potassium channel activity(GO:1902259) |
0.6 | 13.0 | GO:0051491 | positive regulation of filopodium assembly(GO:0051491) |
0.6 | 14.7 | GO:0030325 | adrenal gland development(GO:0030325) |
0.6 | 4.3 | GO:2000232 | regulation of rRNA processing(GO:2000232) |
0.6 | 3.0 | GO:0006041 | glucosamine metabolic process(GO:0006041) |
0.6 | 2.4 | GO:2000194 | regulation of female gonad development(GO:2000194) |
0.6 | 2.4 | GO:0071787 | endoplasmic reticulum tubular network assembly(GO:0071787) |
0.6 | 17.4 | GO:0015985 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
0.6 | 4.2 | GO:0014807 | regulation of somitogenesis(GO:0014807) |
0.6 | 4.1 | GO:0035735 | intraciliary transport involved in cilium morphogenesis(GO:0035735) |
0.6 | 13.4 | GO:0008340 | determination of adult lifespan(GO:0008340) |
0.6 | 4.1 | GO:0030242 | pexophagy(GO:0030242) |
0.6 | 2.3 | GO:0019323 | pentose catabolic process(GO:0019323) |
0.6 | 20.2 | GO:0042773 | ATP synthesis coupled electron transport(GO:0042773) |
0.6 | 3.5 | GO:0034773 | histone H4-K20 trimethylation(GO:0034773) establishment of Sertoli cell barrier(GO:0097368) |
0.6 | 3.5 | GO:1990416 | cellular response to brain-derived neurotrophic factor stimulus(GO:1990416) |
0.6 | 3.4 | GO:0035095 | behavioral response to nicotine(GO:0035095) |
0.6 | 4.0 | GO:0070494 | regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495) |
0.6 | 1.7 | GO:1900623 | regulation of mast cell cytokine production(GO:0032763) monocyte aggregation(GO:0070487) regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625) |
0.6 | 6.2 | GO:0002230 | positive regulation of defense response to virus by host(GO:0002230) |
0.6 | 1.7 | GO:0031914 | negative regulation of synaptic plasticity(GO:0031914) |
0.6 | 38.0 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
0.5 | 4.3 | GO:0000055 | ribosomal large subunit export from nucleus(GO:0000055) ribosomal small subunit export from nucleus(GO:0000056) |
0.5 | 9.2 | GO:0002495 | antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) |
0.5 | 5.9 | GO:0009312 | oligosaccharide biosynthetic process(GO:0009312) |
0.5 | 4.8 | GO:1903608 | protein localization to cytoplasmic stress granule(GO:1903608) |
0.5 | 21.6 | GO:0000381 | regulation of alternative mRNA splicing, via spliceosome(GO:0000381) |
0.5 | 23.2 | GO:0001919 | regulation of receptor recycling(GO:0001919) |
0.5 | 1.6 | GO:0061153 | trachea submucosa development(GO:0061152) trachea gland development(GO:0061153) |
0.5 | 4.7 | GO:0010793 | regulation of mRNA export from nucleus(GO:0010793) regulation of ribonucleoprotein complex localization(GO:2000197) |
0.5 | 4.1 | GO:0010818 | T cell chemotaxis(GO:0010818) |
0.5 | 2.6 | GO:0033234 | regulation of protein sumoylation(GO:0033233) negative regulation of protein sumoylation(GO:0033234) |
0.5 | 3.0 | GO:0034454 | microtubule anchoring at centrosome(GO:0034454) |
0.5 | 4.0 | GO:0010606 | positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606) |
0.5 | 2.5 | GO:0007258 | JUN phosphorylation(GO:0007258) |
0.5 | 4.0 | GO:0021942 | radial glia guided migration of Purkinje cell(GO:0021942) |
0.5 | 4.4 | GO:0061635 | regulation of protein complex stability(GO:0061635) |
0.5 | 6.2 | GO:0031937 | positive regulation of chromatin silencing(GO:0031937) |
0.5 | 1.9 | GO:0097167 | circadian regulation of translation(GO:0097167) |
0.5 | 4.8 | GO:1904754 | positive regulation of vascular associated smooth muscle cell migration(GO:1904754) |
0.5 | 1.9 | GO:0030576 | Cajal body organization(GO:0030576) |
0.5 | 2.3 | GO:0035434 | copper ion transmembrane transport(GO:0035434) |
0.5 | 5.5 | GO:0006895 | Golgi to endosome transport(GO:0006895) |
0.5 | 1.4 | GO:0002184 | cytoplasmic translational termination(GO:0002184) |
0.4 | 4.0 | GO:0051292 | nuclear pore complex assembly(GO:0051292) |
0.4 | 4.5 | GO:0050862 | positive regulation of T cell receptor signaling pathway(GO:0050862) |
0.4 | 1.3 | GO:1904395 | positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) positive regulation of neuromuscular junction development(GO:1904398) |
0.4 | 23.7 | GO:0010977 | negative regulation of neuron projection development(GO:0010977) |
0.4 | 1.7 | GO:0046368 | GDP-L-fucose metabolic process(GO:0046368) |
0.4 | 2.1 | GO:0070562 | regulation of vitamin D receptor signaling pathway(GO:0070562) |
0.4 | 0.4 | GO:1902177 | positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902177) |
0.4 | 0.8 | GO:0048636 | positive regulation of striated muscle tissue development(GO:0045844) positive regulation of muscle organ development(GO:0048636) positive regulation of muscle tissue development(GO:1901863) |
0.4 | 2.5 | GO:1902018 | negative regulation of cilium assembly(GO:1902018) |
0.4 | 31.1 | GO:0031532 | actin cytoskeleton reorganization(GO:0031532) |
0.4 | 13.3 | GO:0046627 | negative regulation of insulin receptor signaling pathway(GO:0046627) |
0.4 | 2.5 | GO:0010839 | negative regulation of keratinocyte proliferation(GO:0010839) |
0.4 | 2.9 | GO:0019800 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800) |
0.4 | 0.8 | GO:0086053 | AV node cell to bundle of His cell communication by electrical coupling(GO:0086053) |
0.4 | 2.4 | GO:1990564 | protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592) |
0.4 | 0.8 | GO:0060523 | prostate epithelial cord elongation(GO:0060523) |
0.4 | 1.2 | GO:0098886 | modification of dendritic spine(GO:0098886) |
0.4 | 12.9 | GO:0007416 | synapse assembly(GO:0007416) |
0.4 | 1.2 | GO:1902951 | negative regulation of dendritic spine maintenance(GO:1902951) |
0.4 | 5.0 | GO:0045793 | positive regulation of cell size(GO:0045793) |
0.4 | 0.4 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
0.4 | 3.4 | GO:0006449 | regulation of translational termination(GO:0006449) |
0.4 | 3.8 | GO:0051604 | protein maturation(GO:0051604) |
0.4 | 2.2 | GO:0048304 | positive regulation of isotype switching to IgG isotypes(GO:0048304) |
0.4 | 1.1 | GO:0089700 | protein kinase D signaling(GO:0089700) |
0.4 | 1.4 | GO:1904425 | negative regulation of GTP binding(GO:1904425) |
0.4 | 2.5 | GO:0050982 | detection of mechanical stimulus(GO:0050982) |
0.3 | 2.4 | GO:1902902 | negative regulation of autophagosome assembly(GO:1902902) |
0.3 | 2.4 | GO:0045017 | glycerolipid biosynthetic process(GO:0045017) |
0.3 | 5.2 | GO:0000380 | alternative mRNA splicing, via spliceosome(GO:0000380) |
0.3 | 4.8 | GO:1900746 | regulation of vascular endothelial growth factor signaling pathway(GO:1900746) |
0.3 | 2.3 | GO:0018243 | protein O-linked glycosylation via threonine(GO:0018243) |
0.3 | 4.4 | GO:0060979 | vasculogenesis involved in coronary vascular morphogenesis(GO:0060979) |
0.3 | 1.0 | GO:0002329 | pre-B cell differentiation(GO:0002329) |
0.3 | 3.3 | GO:0051302 | regulation of cell division(GO:0051302) |
0.3 | 6.9 | GO:0007019 | microtubule depolymerization(GO:0007019) |
0.3 | 3.0 | GO:0006686 | sphingomyelin biosynthetic process(GO:0006686) |
0.3 | 2.0 | GO:0072656 | maintenance of protein location in mitochondrion(GO:0072656) |
0.3 | 1.3 | GO:1902774 | late endosome to lysosome transport(GO:1902774) |
0.3 | 1.0 | GO:0006883 | cellular sodium ion homeostasis(GO:0006883) |
0.3 | 2.3 | GO:0046827 | positive regulation of protein export from nucleus(GO:0046827) |
0.3 | 3.6 | GO:1903301 | positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301) |
0.3 | 0.6 | GO:1905077 | negative regulation of interleukin-17 secretion(GO:1905077) |
0.3 | 1.6 | GO:0045955 | negative regulation of calcium ion-dependent exocytosis(GO:0045955) negative regulation of fertilization(GO:0060467) |
0.3 | 1.6 | GO:0090005 | negative regulation of Golgi to plasma membrane protein transport(GO:0042997) negative regulation of establishment of protein localization to plasma membrane(GO:0090005) |
0.3 | 3.1 | GO:2000051 | negative regulation of non-canonical Wnt signaling pathway(GO:2000051) |
0.3 | 3.4 | GO:0045898 | regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) |
0.3 | 1.5 | GO:0090310 | negative regulation of methylation-dependent chromatin silencing(GO:0090310) |
0.3 | 12.4 | GO:0045773 | positive regulation of axon extension(GO:0045773) |
0.3 | 11.3 | GO:0010765 | positive regulation of sodium ion transport(GO:0010765) |
0.3 | 2.4 | GO:0006390 | transcription from mitochondrial promoter(GO:0006390) |
0.3 | 14.7 | GO:0030032 | lamellipodium assembly(GO:0030032) |
0.3 | 5.6 | GO:0045116 | protein neddylation(GO:0045116) |
0.3 | 2.6 | GO:0006020 | inositol metabolic process(GO:0006020) |
0.3 | 5.9 | GO:0007212 | dopamine receptor signaling pathway(GO:0007212) |
0.3 | 14.2 | GO:0038083 | peptidyl-tyrosine autophosphorylation(GO:0038083) |
0.3 | 4.7 | GO:0006613 | cotranslational protein targeting to membrane(GO:0006613) |
0.3 | 7.5 | GO:0045494 | photoreceptor cell maintenance(GO:0045494) |
0.3 | 2.2 | GO:0072600 | establishment of protein localization to Golgi(GO:0072600) |
0.3 | 1.3 | GO:0042795 | snRNA transcription from RNA polymerase II promoter(GO:0042795) |
0.3 | 2.7 | GO:0006968 | cellular defense response(GO:0006968) |
0.3 | 0.5 | GO:0001951 | intestinal D-glucose absorption(GO:0001951) regulation of microvillus length(GO:0032532) terminal web assembly(GO:1902896) |
0.3 | 0.8 | GO:1904059 | regulation of locomotor rhythm(GO:1904059) |
0.3 | 0.8 | GO:0097089 | methyl-branched fatty acid metabolic process(GO:0097089) |
0.3 | 4.0 | GO:0060074 | synapse maturation(GO:0060074) |
0.3 | 4.7 | GO:1901381 | positive regulation of potassium ion transmembrane transport(GO:1901381) |
0.3 | 5.1 | GO:0044342 | type B pancreatic cell proliferation(GO:0044342) |
0.3 | 1.0 | GO:1904565 | response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566) |
0.3 | 3.5 | GO:2000311 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311) |
0.3 | 1.3 | GO:0046543 | development of secondary sexual characteristics(GO:0045136) development of secondary female sexual characteristics(GO:0046543) |
0.3 | 2.0 | GO:0032876 | negative regulation of DNA endoreduplication(GO:0032876) |
0.3 | 0.8 | GO:0071415 | cellular response to caffeine(GO:0071313) cellular response to purine-containing compound(GO:0071415) |
0.2 | 3.2 | GO:0021860 | pyramidal neuron development(GO:0021860) |
0.2 | 5.7 | GO:0016180 | snRNA processing(GO:0016180) |
0.2 | 5.0 | GO:0003351 | epithelial cilium movement(GO:0003351) |
0.2 | 2.2 | GO:0003084 | positive regulation of systemic arterial blood pressure(GO:0003084) |
0.2 | 1.2 | GO:2000623 | regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623) |
0.2 | 3.3 | GO:0045974 | miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974) |
0.2 | 4.3 | GO:0050650 | chondroitin sulfate proteoglycan biosynthetic process(GO:0050650) |
0.2 | 4.2 | GO:0006622 | protein targeting to lysosome(GO:0006622) |
0.2 | 1.6 | GO:0090557 | establishment of endothelial intestinal barrier(GO:0090557) |
0.2 | 2.3 | GO:0015701 | bicarbonate transport(GO:0015701) |
0.2 | 3.0 | GO:0035970 | peptidyl-threonine dephosphorylation(GO:0035970) |
0.2 | 9.6 | GO:0046580 | negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058) |
0.2 | 1.7 | GO:0007016 | cytoskeletal anchoring at plasma membrane(GO:0007016) |
0.2 | 1.7 | GO:0031274 | positive regulation of pseudopodium assembly(GO:0031274) |
0.2 | 1.1 | GO:0048133 | germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728) |
0.2 | 0.6 | GO:0051030 | snRNA transport(GO:0051030) |
0.2 | 1.5 | GO:2000124 | regulation of endocannabinoid signaling pathway(GO:2000124) |
0.2 | 3.1 | GO:0060218 | hematopoietic stem cell differentiation(GO:0060218) |
0.2 | 23.9 | GO:0007266 | Rho protein signal transduction(GO:0007266) |
0.2 | 31.2 | GO:0016358 | dendrite development(GO:0016358) |
0.2 | 0.2 | GO:0043402 | glucocorticoid mediated signaling pathway(GO:0043402) |
0.2 | 1.6 | GO:0035608 | protein deglutamylation(GO:0035608) |
0.2 | 12.7 | GO:0019722 | calcium-mediated signaling(GO:0019722) |
0.2 | 2.4 | GO:0000281 | mitotic cytokinesis(GO:0000281) |
0.2 | 5.2 | GO:0014037 | Schwann cell differentiation(GO:0014037) |
0.2 | 0.8 | GO:0010603 | regulation of cytoplasmic mRNA processing body assembly(GO:0010603) |
0.2 | 0.8 | GO:0051574 | positive regulation of histone H3-K9 methylation(GO:0051574) |
0.2 | 4.7 | GO:0030851 | granulocyte differentiation(GO:0030851) |
0.2 | 1.9 | GO:1900364 | negative regulation of mRNA polyadenylation(GO:1900364) |
0.2 | 1.3 | GO:2000507 | negative regulation of peptidyl-threonine phosphorylation(GO:0010801) positive regulation of energy homeostasis(GO:2000507) |
0.2 | 3.8 | GO:0007193 | adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193) |
0.2 | 8.5 | GO:0045600 | positive regulation of fat cell differentiation(GO:0045600) |
0.2 | 3.0 | GO:0006491 | N-glycan processing(GO:0006491) |
0.2 | 1.1 | GO:0001895 | retina homeostasis(GO:0001895) |
0.2 | 4.8 | GO:0071108 | protein K48-linked deubiquitination(GO:0071108) |
0.2 | 2.2 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
0.2 | 3.3 | GO:0033169 | histone H3-K9 demethylation(GO:0033169) |
0.2 | 1.8 | GO:0048670 | regulation of collateral sprouting(GO:0048670) |
0.2 | 1.1 | GO:0097120 | receptor localization to synapse(GO:0097120) |
0.2 | 4.9 | GO:0000460 | maturation of 5.8S rRNA(GO:0000460) |
0.2 | 6.0 | GO:0046324 | regulation of glucose import(GO:0046324) |
0.2 | 1.0 | GO:0034587 | piRNA metabolic process(GO:0034587) |
0.2 | 0.7 | GO:0043931 | ossification involved in bone maturation(GO:0043931) |
0.2 | 0.7 | GO:0034058 | endosomal vesicle fusion(GO:0034058) |
0.2 | 0.8 | GO:0043353 | enucleate erythrocyte differentiation(GO:0043353) |
0.2 | 0.8 | GO:0051684 | maintenance of Golgi location(GO:0051684) |
0.2 | 1.0 | GO:0071494 | cellular response to UV-C(GO:0071494) |
0.2 | 2.0 | GO:0006110 | regulation of glycolytic process(GO:0006110) |
0.2 | 2.7 | GO:0060009 | Sertoli cell development(GO:0060009) |
0.2 | 3.0 | GO:0032467 | positive regulation of cytokinesis(GO:0032467) |
0.2 | 1.3 | GO:0046085 | adenosine metabolic process(GO:0046085) |
0.2 | 0.3 | GO:0060800 | regulation of cell differentiation involved in embryonic placenta development(GO:0060800) |
0.2 | 1.6 | GO:0034453 | microtubule anchoring(GO:0034453) |
0.2 | 0.6 | GO:0089711 | L-glutamate transmembrane transport(GO:0089711) |
0.2 | 0.5 | GO:0010873 | positive regulation of cholesterol esterification(GO:0010873) |
0.2 | 1.5 | GO:0014002 | astrocyte development(GO:0014002) |
0.2 | 2.6 | GO:0002063 | chondrocyte development(GO:0002063) |
0.1 | 1.6 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
0.1 | 7.5 | GO:0050770 | regulation of axonogenesis(GO:0050770) |
0.1 | 0.4 | GO:1904181 | positive regulation of membrane depolarization(GO:1904181) |
0.1 | 0.7 | GO:0097090 | presynaptic membrane organization(GO:0097090) |
0.1 | 0.6 | GO:0042138 | meiotic DNA double-strand break formation(GO:0042138) |
0.1 | 1.3 | GO:0048386 | positive regulation of retinoic acid receptor signaling pathway(GO:0048386) |
0.1 | 1.1 | GO:0007250 | activation of NF-kappaB-inducing kinase activity(GO:0007250) |
0.1 | 1.8 | GO:0043252 | sodium-independent organic anion transport(GO:0043252) |
0.1 | 2.4 | GO:0030970 | retrograde protein transport, ER to cytosol(GO:0030970) |
0.1 | 0.4 | GO:0048149 | behavioral response to ethanol(GO:0048149) |
0.1 | 4.7 | GO:0042073 | intraciliary transport(GO:0042073) |
0.1 | 1.9 | GO:0030865 | cortical cytoskeleton organization(GO:0030865) |
0.1 | 8.9 | GO:0014065 | phosphatidylinositol 3-kinase signaling(GO:0014065) |
0.1 | 3.8 | GO:0008361 | regulation of cell size(GO:0008361) |
0.1 | 0.6 | GO:0015788 | UDP-N-acetylglucosamine transport(GO:0015788) |
0.1 | 7.9 | GO:0006487 | protein N-linked glycosylation(GO:0006487) |
0.1 | 0.6 | GO:0051152 | positive regulation of smooth muscle cell differentiation(GO:0051152) |
0.1 | 3.4 | GO:0010569 | regulation of double-strand break repair via homologous recombination(GO:0010569) |
0.1 | 1.5 | GO:0000729 | DNA double-strand break processing(GO:0000729) |
0.1 | 1.3 | GO:0033211 | adiponectin-activated signaling pathway(GO:0033211) |
0.1 | 1.8 | GO:0042254 | ribosome biogenesis(GO:0042254) |
0.1 | 4.2 | GO:0032091 | negative regulation of protein binding(GO:0032091) |
0.1 | 0.5 | GO:2000346 | negative regulation of hepatocyte proliferation(GO:2000346) |
0.1 | 1.9 | GO:0045063 | T-helper 1 cell differentiation(GO:0045063) |
0.1 | 1.5 | GO:0043248 | proteasome assembly(GO:0043248) |
0.1 | 27.9 | GO:0007186 | G-protein coupled receptor signaling pathway(GO:0007186) |
0.1 | 1.2 | GO:1903077 | negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376) |
0.1 | 3.8 | GO:0006779 | porphyrin-containing compound biosynthetic process(GO:0006779) |
0.1 | 1.8 | GO:0048009 | insulin-like growth factor receptor signaling pathway(GO:0048009) |
0.1 | 3.2 | GO:0097576 | autophagosome maturation(GO:0097352) vacuole fusion(GO:0097576) |
0.1 | 2.0 | GO:0043984 | histone H4-K16 acetylation(GO:0043984) |
0.1 | 2.0 | GO:0043001 | Golgi to plasma membrane protein transport(GO:0043001) |
0.1 | 0.4 | GO:0035826 | rubidium ion transport(GO:0035826) cellular hypotonic response(GO:0071476) |
0.1 | 0.4 | GO:0045075 | interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075) |
0.1 | 4.0 | GO:0006270 | DNA replication initiation(GO:0006270) |
0.1 | 2.8 | GO:0000462 | maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462) |
0.1 | 4.5 | GO:0030071 | regulation of mitotic metaphase/anaphase transition(GO:0030071) regulation of metaphase/anaphase transition of cell cycle(GO:1902099) |
0.1 | 5.1 | GO:0032436 | positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) |
0.1 | 0.7 | GO:0006297 | nucleotide-excision repair, DNA gap filling(GO:0006297) |
0.1 | 0.2 | GO:0072488 | ammonium transmembrane transport(GO:0072488) |
0.1 | 0.9 | GO:0042135 | neurotransmitter catabolic process(GO:0042135) |
0.1 | 3.9 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
0.1 | 2.8 | GO:0050688 | regulation of defense response to virus(GO:0050688) |
0.1 | 0.6 | GO:0051418 | interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418) |
0.1 | 4.7 | GO:0050806 | positive regulation of synaptic transmission(GO:0050806) |
0.1 | 0.7 | GO:0043173 | nucleotide salvage(GO:0043173) |
0.1 | 6.0 | GO:0071805 | potassium ion transmembrane transport(GO:0071805) |
0.1 | 4.9 | GO:0001578 | microtubule bundle formation(GO:0001578) |
0.1 | 3.1 | GO:0007029 | endoplasmic reticulum organization(GO:0007029) |
0.1 | 0.2 | GO:0046689 | response to mercury ion(GO:0046689) |
0.1 | 1.4 | GO:0010172 | embryonic body morphogenesis(GO:0010172) |
0.1 | 0.2 | GO:0061743 | motor learning(GO:0061743) |
0.1 | 3.6 | GO:0080171 | lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171) |
0.1 | 0.9 | GO:0000244 | spliceosomal tri-snRNP complex assembly(GO:0000244) |
0.1 | 0.2 | GO:0035235 | ionotropic glutamate receptor signaling pathway(GO:0035235) |
0.1 | 0.8 | GO:0006261 | DNA-dependent DNA replication(GO:0006261) |
0.1 | 0.2 | GO:0015677 | copper ion import(GO:0015677) |
0.1 | 0.7 | GO:0097186 | amelogenesis(GO:0097186) |
0.1 | 2.1 | GO:0030048 | actin filament-based movement(GO:0030048) |
0.1 | 2.1 | GO:2000378 | negative regulation of reactive oxygen species metabolic process(GO:2000378) |
0.1 | 3.9 | GO:0042147 | retrograde transport, endosome to Golgi(GO:0042147) |
0.1 | 1.0 | GO:0005980 | polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247) |
0.1 | 1.2 | GO:0045806 | negative regulation of endocytosis(GO:0045806) |
0.0 | 0.8 | GO:0018345 | protein palmitoylation(GO:0018345) |
0.0 | 0.3 | GO:0046548 | retinal rod cell development(GO:0046548) |
0.0 | 0.3 | GO:0035459 | cargo loading into vesicle(GO:0035459) cargo loading into COPII-coated vesicle(GO:0090110) |
0.0 | 0.2 | GO:0070050 | neuron cellular homeostasis(GO:0070050) |
0.0 | 0.5 | GO:0035308 | negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308) |
0.0 | 3.2 | GO:0031032 | actomyosin structure organization(GO:0031032) |
0.0 | 0.5 | GO:0035019 | somatic stem cell population maintenance(GO:0035019) |
0.0 | 0.8 | GO:0035036 | binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036) |
0.0 | 2.9 | GO:0051028 | mRNA transport(GO:0051028) |
0.0 | 1.9 | GO:0043154 | negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154) |
0.0 | 0.1 | GO:0072321 | chaperone-mediated protein transport(GO:0072321) |
0.0 | 1.4 | GO:0007030 | Golgi organization(GO:0007030) |
0.0 | 4.2 | GO:0018209 | peptidyl-serine modification(GO:0018209) |
0.0 | 1.9 | GO:0000086 | G2/M transition of mitotic cell cycle(GO:0000086) |
0.0 | 0.1 | GO:0046462 | monoacylglycerol metabolic process(GO:0046462) |
0.0 | 0.1 | GO:0042177 | negative regulation of protein catabolic process(GO:0042177) |
0.0 | 0.1 | GO:1902083 | negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083) |
0.0 | 0.1 | GO:0035616 | histone H2B conserved C-terminal lysine deubiquitination(GO:0035616) |
0.0 | 0.1 | GO:0061365 | positive regulation of triglyceride lipase activity(GO:0061365) |
0.0 | 0.8 | GO:0006342 | chromatin silencing(GO:0006342) |
0.0 | 0.1 | GO:0045930 | negative regulation of mitotic cell cycle(GO:0045930) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
12.2 | 36.7 | GO:0043512 | inhibin A complex(GO:0043512) |
10.4 | 41.6 | GO:0031673 | H zone(GO:0031673) |
7.0 | 21.0 | GO:0072534 | perineuronal net(GO:0072534) |
6.9 | 34.5 | GO:0032437 | cuticular plate(GO:0032437) |
6.3 | 57.1 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
4.9 | 43.7 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
4.6 | 69.2 | GO:0043083 | synaptic cleft(GO:0043083) |
4.1 | 78.4 | GO:0071564 | npBAF complex(GO:0071564) |
3.8 | 64.4 | GO:0031045 | dense core granule(GO:0031045) |
3.5 | 52.8 | GO:1902711 | GABA-A receptor complex(GO:1902711) |
3.0 | 60.9 | GO:0014731 | spectrin-associated cytoskeleton(GO:0014731) |
3.0 | 78.4 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
3.0 | 14.9 | GO:0000308 | cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308) |
2.9 | 11.5 | GO:1990452 | Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452) |
2.8 | 42.3 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
2.5 | 52.0 | GO:0031430 | M band(GO:0031430) |
2.4 | 11.9 | GO:0098831 | presynaptic active zone cytoplasmic component(GO:0098831) |
2.0 | 32.2 | GO:0043196 | varicosity(GO:0043196) |
2.0 | 25.9 | GO:0017146 | NMDA selective glutamate receptor complex(GO:0017146) |
2.0 | 41.3 | GO:1990124 | messenger ribonucleoprotein complex(GO:1990124) |
1.7 | 467.7 | GO:0045211 | postsynaptic membrane(GO:0045211) |
1.6 | 6.3 | GO:0071006 | U2-type catalytic step 1 spliceosome(GO:0071006) |
1.6 | 7.9 | GO:0000235 | astral microtubule(GO:0000235) |
1.5 | 7.6 | GO:0070826 | paraferritin complex(GO:0070826) |
1.4 | 4.2 | GO:0005943 | phosphatidylinositol 3-kinase complex, class IA(GO:0005943) |
1.4 | 16.5 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
1.4 | 17.6 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
1.3 | 39.9 | GO:0032809 | neuronal cell body membrane(GO:0032809) |
1.2 | 45.0 | GO:0097458 | neuron part(GO:0097458) |
1.1 | 11.3 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
1.1 | 36.1 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
1.1 | 3.4 | GO:0099573 | glutamatergic postsynaptic density(GO:0099573) |
1.1 | 5.5 | GO:0031466 | Cul5-RING ubiquitin ligase complex(GO:0031466) |
1.1 | 4.3 | GO:0001651 | dense fibrillar component(GO:0001651) |
1.1 | 11.7 | GO:0030122 | AP-2 adaptor complex(GO:0030122) |
1.0 | 14.5 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
1.0 | 13.3 | GO:0097542 | ciliary tip(GO:0097542) |
1.0 | 42.2 | GO:0044295 | axonal growth cone(GO:0044295) |
1.0 | 4.9 | GO:0005968 | Rab-protein geranylgeranyltransferase complex(GO:0005968) |
1.0 | 22.4 | GO:0097038 | perinuclear endoplasmic reticulum(GO:0097038) |
1.0 | 8.6 | GO:0044294 | dendritic growth cone(GO:0044294) |
0.9 | 3.7 | GO:0033269 | internode region of axon(GO:0033269) |
0.9 | 3.4 | GO:0008623 | CHRAC(GO:0008623) |
0.9 | 4.3 | GO:0070937 | CRD-mediated mRNA stability complex(GO:0070937) |
0.8 | 9.5 | GO:0002178 | palmitoyltransferase complex(GO:0002178) |
0.8 | 7.9 | GO:0016010 | dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665) |
0.8 | 7.9 | GO:0071439 | clathrin complex(GO:0071439) |
0.8 | 15.6 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
0.8 | 10.8 | GO:0042788 | polysomal ribosome(GO:0042788) |
0.8 | 3.0 | GO:0000791 | euchromatin(GO:0000791) |
0.7 | 8.7 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
0.7 | 7.9 | GO:0045275 | respiratory chain complex III(GO:0045275) |
0.7 | 12.8 | GO:0031226 | intrinsic component of plasma membrane(GO:0031226) |
0.7 | 2.7 | GO:0031983 | vesicle lumen(GO:0031983) |
0.7 | 30.3 | GO:0044291 | cell-cell contact zone(GO:0044291) |
0.7 | 3.9 | GO:0034388 | Pwp2p-containing subcomplex of 90S preribosome(GO:0034388) |
0.6 | 8.2 | GO:0042581 | specific granule(GO:0042581) |
0.6 | 3.7 | GO:0031313 | extrinsic component of endosome membrane(GO:0031313) |
0.6 | 4.8 | GO:0097165 | nuclear stress granule(GO:0097165) |
0.6 | 1.7 | GO:0044305 | calyx of Held(GO:0044305) |
0.6 | 33.8 | GO:0070469 | respiratory chain(GO:0070469) |
0.5 | 1.6 | GO:0008091 | spectrin(GO:0008091) |
0.5 | 15.7 | GO:0042734 | presynaptic membrane(GO:0042734) |
0.5 | 2.6 | GO:0032585 | multivesicular body membrane(GO:0032585) |
0.5 | 1.5 | GO:0071012 | catalytic step 1 spliceosome(GO:0071012) |
0.5 | 104.0 | GO:0060076 | excitatory synapse(GO:0060076) |
0.5 | 4.0 | GO:0030015 | CCR4-NOT core complex(GO:0030015) |
0.5 | 6.5 | GO:1990635 | proximal dendrite(GO:1990635) |
0.5 | 8.4 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
0.5 | 4.9 | GO:0070545 | PeBoW complex(GO:0070545) |
0.5 | 3.5 | GO:0071437 | invadopodium(GO:0071437) |
0.5 | 14.7 | GO:0009986 | cell surface(GO:0009986) |
0.5 | 1.9 | GO:0005726 | perichromatin fibrils(GO:0005726) |
0.5 | 15.3 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
0.5 | 3.3 | GO:0070695 | FHF complex(GO:0070695) |
0.5 | 1.4 | GO:0043540 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540) |
0.5 | 2.4 | GO:0000839 | Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839) |
0.5 | 22.5 | GO:0016328 | lateral plasma membrane(GO:0016328) |
0.5 | 1.4 | GO:0018444 | translation release factor complex(GO:0018444) |
0.5 | 1.8 | GO:0097454 | Schwann cell microvillus(GO:0097454) |
0.4 | 8.4 | GO:0097228 | sperm principal piece(GO:0097228) |
0.4 | 3.5 | GO:0005786 | signal recognition particle, endoplasmic reticulum targeting(GO:0005786) |
0.4 | 4.4 | GO:0030132 | clathrin coat of coated pit(GO:0030132) |
0.4 | 56.2 | GO:0030017 | sarcomere(GO:0030017) |
0.4 | 3.8 | GO:0030673 | axolemma(GO:0030673) |
0.4 | 6.8 | GO:0032039 | integrator complex(GO:0032039) |
0.4 | 2.9 | GO:0005677 | chromatin silencing complex(GO:0005677) |
0.4 | 6.3 | GO:0042101 | T cell receptor complex(GO:0042101) |
0.4 | 2.9 | GO:0000220 | vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220) |
0.4 | 2.0 | GO:0072487 | MSL complex(GO:0072487) |
0.4 | 36.2 | GO:0016605 | PML body(GO:0016605) |
0.4 | 3.6 | GO:0035068 | micro-ribonucleoprotein complex(GO:0035068) |
0.4 | 4.3 | GO:0005642 | annulate lamellae(GO:0005642) |
0.4 | 9.8 | GO:0001917 | photoreceptor inner segment(GO:0001917) |
0.4 | 14.3 | GO:0005719 | nuclear euchromatin(GO:0005719) |
0.4 | 1.5 | GO:0045334 | clathrin-coated endocytic vesicle(GO:0045334) |
0.4 | 4.1 | GO:0030175 | filopodium(GO:0030175) |
0.4 | 1.1 | GO:1902937 | inward rectifier potassium channel complex(GO:1902937) |
0.4 | 1.8 | GO:0033116 | endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116) |
0.4 | 37.7 | GO:0016363 | nuclear matrix(GO:0016363) |
0.3 | 27.5 | GO:0042641 | actomyosin(GO:0042641) |
0.3 | 4.5 | GO:0031464 | Cul4A-RING E3 ubiquitin ligase complex(GO:0031464) |
0.3 | 2.4 | GO:0098554 | cytoplasmic side of endoplasmic reticulum membrane(GO:0098554) |
0.3 | 269.9 | GO:0005887 | integral component of plasma membrane(GO:0005887) |
0.3 | 4.9 | GO:0030127 | COPII vesicle coat(GO:0030127) |
0.3 | 3.3 | GO:0031595 | nuclear proteasome complex(GO:0031595) |
0.3 | 4.3 | GO:0043198 | dendritic shaft(GO:0043198) |
0.3 | 0.3 | GO:0051286 | cell tip(GO:0051286) |
0.3 | 28.2 | GO:0031225 | anchored component of membrane(GO:0031225) |
0.3 | 6.1 | GO:0030139 | endocytic vesicle(GO:0030139) |
0.3 | 12.5 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
0.3 | 23.1 | GO:0031234 | extrinsic component of cytoplasmic side of plasma membrane(GO:0031234) |
0.2 | 12.5 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
0.2 | 27.3 | GO:0036064 | ciliary basal body(GO:0036064) |
0.2 | 2.1 | GO:0032541 | cortical endoplasmic reticulum(GO:0032541) |
0.2 | 0.2 | GO:0097487 | amphisome(GO:0044753) multivesicular body, internal vesicle(GO:0097487) |
0.2 | 2.6 | GO:0005832 | chaperonin-containing T-complex(GO:0005832) |
0.2 | 1.3 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
0.2 | 1.1 | GO:0042824 | MHC class I peptide loading complex(GO:0042824) |
0.2 | 17.3 | GO:0044798 | nuclear transcription factor complex(GO:0044798) |
0.2 | 0.5 | GO:1990357 | terminal web(GO:1990357) |
0.2 | 1.0 | GO:0060293 | P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293) |
0.2 | 1.5 | GO:0071565 | nBAF complex(GO:0071565) |
0.2 | 4.2 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
0.2 | 1.6 | GO:0072669 | tRNA-splicing ligase complex(GO:0072669) |
0.2 | 0.6 | GO:0070876 | SOSS complex(GO:0070876) |
0.2 | 15.1 | GO:0000118 | histone deacetylase complex(GO:0000118) |
0.2 | 0.3 | GO:0030478 | actin cap(GO:0030478) |
0.1 | 3.1 | GO:0070971 | endoplasmic reticulum exit site(GO:0070971) |
0.1 | 3.7 | GO:0071339 | MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339) |
0.1 | 9.0 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
0.1 | 5.6 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
0.1 | 0.7 | GO:0033263 | CORVET complex(GO:0033263) |
0.1 | 0.8 | GO:0097550 | transcriptional preinitiation complex(GO:0097550) |
0.1 | 1.7 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
0.1 | 3.2 | GO:0009898 | cytoplasmic side of plasma membrane(GO:0009898) |
0.1 | 1.3 | GO:0097470 | ribbon synapse(GO:0097470) |
0.1 | 3.4 | GO:0035861 | site of double-strand break(GO:0035861) |
0.1 | 2.4 | GO:0012505 | endomembrane system(GO:0012505) |
0.1 | 6.5 | GO:0005791 | rough endoplasmic reticulum(GO:0005791) |
0.1 | 1.7 | GO:0001772 | immunological synapse(GO:0001772) |
0.1 | 3.8 | GO:0005801 | cis-Golgi network(GO:0005801) |
0.1 | 3.6 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
0.1 | 1.5 | GO:0005771 | multivesicular body(GO:0005771) |
0.1 | 2.7 | GO:0035371 | microtubule plus-end(GO:0035371) |
0.1 | 10.0 | GO:0005802 | trans-Golgi network(GO:0005802) |
0.1 | 8.3 | GO:0055037 | recycling endosome(GO:0055037) |
0.1 | 1.7 | GO:0043189 | NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562) |
0.1 | 21.9 | GO:0000139 | Golgi membrane(GO:0000139) |
0.1 | 2.3 | GO:0045335 | phagocytic vesicle(GO:0045335) |
0.1 | 1.2 | GO:0071782 | endoplasmic reticulum tubular network(GO:0071782) |
0.1 | 11.9 | GO:0005770 | late endosome(GO:0005770) |
0.1 | 1.0 | GO:0097223 | sperm flagellum(GO:0036126) sperm part(GO:0097223) |
0.1 | 2.9 | GO:0008180 | COP9 signalosome(GO:0008180) |
0.1 | 1.1 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
0.1 | 2.5 | GO:0030864 | cortical actin cytoskeleton(GO:0030864) |
0.1 | 1.2 | GO:0005923 | bicellular tight junction(GO:0005923) |
0.1 | 2.3 | GO:0005902 | microvillus(GO:0005902) |
0.1 | 0.8 | GO:0000347 | THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445) |
0.1 | 2.3 | GO:0031306 | intrinsic component of mitochondrial outer membrane(GO:0031306) |
0.1 | 3.0 | GO:0032587 | ruffle membrane(GO:0032587) |
0.1 | 1.6 | GO:0034399 | nuclear periphery(GO:0034399) |
0.1 | 4.9 | GO:0005643 | nuclear pore(GO:0005643) |
0.1 | 0.7 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
0.1 | 3.4 | GO:0001669 | acrosomal vesicle(GO:0001669) |
0.1 | 3.4 | GO:0005657 | replication fork(GO:0005657) |
0.1 | 2.5 | GO:0005871 | kinesin complex(GO:0005871) |
0.1 | 12.0 | GO:0005635 | nuclear envelope(GO:0005635) |
0.1 | 27.6 | GO:0015630 | microtubule cytoskeleton(GO:0015630) |
0.0 | 0.2 | GO:0008537 | proteasome activator complex(GO:0008537) |
0.0 | 3.8 | GO:0044455 | mitochondrial membrane part(GO:0044455) |
0.0 | 0.7 | GO:0005790 | smooth endoplasmic reticulum(GO:0005790) |
0.0 | 0.9 | GO:0005682 | U5 snRNP(GO:0005682) |
0.0 | 4.5 | GO:0045202 | synapse(GO:0045202) |
0.0 | 24.7 | GO:0005730 | nucleolus(GO:0005730) |
0.0 | 0.2 | GO:0009925 | basal plasma membrane(GO:0009925) |
0.0 | 2.1 | GO:0098852 | lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852) |
0.0 | 0.8 | GO:0031231 | integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231) |
0.0 | 0.2 | GO:0072357 | PTW/PP1 phosphatase complex(GO:0072357) |
0.0 | 2.1 | GO:0005769 | early endosome(GO:0005769) |
0.0 | 0.5 | GO:0080008 | Cul4-RING E3 ubiquitin ligase complex(GO:0080008) |
0.0 | 20.2 | GO:0005794 | Golgi apparatus(GO:0005794) |
0.0 | 0.9 | GO:0072562 | blood microparticle(GO:0072562) |
0.0 | 0.4 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
0.0 | 3.5 | GO:0005681 | spliceosomal complex(GO:0005681) |
0.0 | 0.5 | GO:0043204 | perikaryon(GO:0043204) |
0.0 | 1.0 | GO:0072686 | mitotic spindle(GO:0072686) |
0.0 | 0.2 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
0.0 | 0.9 | GO:0043235 | receptor complex(GO:0043235) |
0.0 | 8.5 | GO:0005783 | endoplasmic reticulum(GO:0005783) |
0.0 | 0.3 | GO:0043195 | terminal bouton(GO:0043195) |
0.0 | 0.0 | GO:0043209 | myelin sheath(GO:0043209) |
0.0 | 0.1 | GO:0000176 | nuclear exosome (RNase complex)(GO:0000176) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
13.5 | 54.2 | GO:0030348 | syntaxin-3 binding(GO:0030348) |
8.7 | 69.4 | GO:0005519 | cytoskeletal regulatory protein binding(GO:0005519) |
8.5 | 50.8 | GO:0070699 | type II activin receptor binding(GO:0070699) |
7.7 | 61.6 | GO:0099529 | neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) |
7.1 | 7.1 | GO:0031697 | beta-1 adrenergic receptor binding(GO:0031697) |
6.5 | 19.5 | GO:0016934 | extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934) |
5.0 | 25.2 | GO:0004971 | AMPA glutamate receptor activity(GO:0004971) |
5.0 | 15.1 | GO:0000822 | inositol hexakisphosphate binding(GO:0000822) |
5.0 | 54.8 | GO:0019531 | secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531) |
4.9 | 19.4 | GO:0004952 | dopamine neurotransmitter receptor activity(GO:0004952) |
4.7 | 33.1 | GO:0048101 | calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101) |
4.4 | 13.2 | GO:0008502 | melatonin receptor activity(GO:0008502) |
4.2 | 29.3 | GO:0015016 | [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016) |
4.2 | 16.7 | GO:0047275 | glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275) |
4.1 | 107.3 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
4.1 | 78.4 | GO:0035198 | miRNA binding(GO:0035198) |
3.9 | 19.7 | GO:0008454 | alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454) |
3.9 | 15.7 | GO:0086038 | calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038) |
3.8 | 30.4 | GO:0005004 | GPI-linked ephrin receptor activity(GO:0005004) |
3.5 | 10.5 | GO:0050501 | hyaluronan synthase activity(GO:0050501) |
3.3 | 32.8 | GO:0042043 | neurexin family protein binding(GO:0042043) |
3.2 | 12.8 | GO:0019808 | polyamine binding(GO:0019808) |
3.0 | 164.3 | GO:0036002 | pre-mRNA binding(GO:0036002) |
2.9 | 14.3 | GO:0004359 | glutaminase activity(GO:0004359) |
2.7 | 10.9 | GO:0043125 | ErbB-3 class receptor binding(GO:0043125) |
2.7 | 32.2 | GO:0097109 | neuroligin family protein binding(GO:0097109) |
2.7 | 13.4 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
2.7 | 8.0 | GO:0008330 | protein tyrosine/threonine phosphatase activity(GO:0008330) |
2.7 | 42.6 | GO:0004890 | GABA-A receptor activity(GO:0004890) |
2.5 | 22.8 | GO:0005025 | transforming growth factor beta receptor activity, type I(GO:0005025) |
2.4 | 53.9 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
2.4 | 9.5 | GO:0017095 | heparan sulfate 6-O-sulfotransferase activity(GO:0017095) |
2.3 | 11.5 | GO:0050816 | phosphothreonine binding(GO:0050816) |
2.3 | 9.1 | GO:0098960 | postsynaptic neurotransmitter receptor activity(GO:0098960) neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583) |
2.2 | 6.6 | GO:0070890 | L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890) |
2.2 | 11.0 | GO:0005166 | neurotrophin p75 receptor binding(GO:0005166) |
2.1 | 6.3 | GO:0005030 | neurotrophin receptor activity(GO:0005030) |
2.1 | 4.1 | GO:0008046 | axon guidance receptor activity(GO:0008046) |
2.0 | 8.2 | GO:0072320 | volume-sensitive chloride channel activity(GO:0072320) |
2.0 | 57.1 | GO:1905030 | voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030) |
1.9 | 98.8 | GO:0046875 | ephrin receptor binding(GO:0046875) |
1.9 | 31.0 | GO:0004385 | guanylate kinase activity(GO:0004385) |
1.9 | 7.5 | GO:0050833 | pyruvate transmembrane transporter activity(GO:0050833) |
1.9 | 33.7 | GO:0000900 | translation repressor activity, nucleic acid binding(GO:0000900) |
1.8 | 22.1 | GO:0050897 | cobalt ion binding(GO:0050897) |
1.8 | 9.2 | GO:0005432 | calcium:sodium antiporter activity(GO:0005432) |
1.8 | 18.2 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
1.8 | 8.9 | GO:0055100 | adiponectin binding(GO:0055100) |
1.8 | 15.9 | GO:0031802 | type 5 metabotropic glutamate receptor binding(GO:0031802) |
1.7 | 100.6 | GO:0030507 | spectrin binding(GO:0030507) |
1.7 | 20.8 | GO:0005078 | MAP-kinase scaffold activity(GO:0005078) |
1.7 | 5.0 | GO:0060072 | large conductance calcium-activated potassium channel activity(GO:0060072) |
1.6 | 33.3 | GO:0030506 | ankyrin binding(GO:0030506) |
1.4 | 4.3 | GO:0044547 | DNA topoisomerase binding(GO:0044547) |
1.4 | 11.4 | GO:0002162 | dystroglycan binding(GO:0002162) |
1.4 | 4.2 | GO:0004111 | creatine kinase activity(GO:0004111) |
1.4 | 40.8 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
1.4 | 4.1 | GO:0022833 | mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833) |
1.3 | 40.4 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
1.3 | 6.5 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
1.3 | 45.9 | GO:0070412 | R-SMAD binding(GO:0070412) |
1.3 | 6.3 | GO:0043812 | phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812) |
1.2 | 4.8 | GO:0001011 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) |
1.2 | 21.0 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
1.1 | 3.4 | GO:0016015 | morphogen activity(GO:0016015) |
1.1 | 36.2 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
1.1 | 15.3 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
1.1 | 17.9 | GO:0030275 | LRR domain binding(GO:0030275) |
1.0 | 3.0 | GO:0016262 | protein N-acetylglucosaminyltransferase activity(GO:0016262) |
1.0 | 7.1 | GO:0035727 | lysophosphatidic acid binding(GO:0035727) |
1.0 | 30.2 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
1.0 | 7.9 | GO:0008121 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
1.0 | 4.0 | GO:0005008 | hepatocyte growth factor-activated receptor activity(GO:0005008) |
1.0 | 15.8 | GO:0046625 | sphingolipid binding(GO:0046625) |
1.0 | 8.8 | GO:0005523 | tropomyosin binding(GO:0005523) |
1.0 | 34.4 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
0.9 | 3.8 | GO:0000179 | rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) |
0.9 | 18.1 | GO:0043422 | protein kinase B binding(GO:0043422) |
0.9 | 4.4 | GO:0050265 | RNA uridylyltransferase activity(GO:0050265) |
0.9 | 27.8 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
0.8 | 5.9 | GO:0001665 | alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665) |
0.8 | 2.5 | GO:0016909 | JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909) |
0.8 | 4.1 | GO:0070700 | BMP receptor binding(GO:0070700) |
0.8 | 2.4 | GO:0008195 | phosphatidate phosphatase activity(GO:0008195) |
0.8 | 2.4 | GO:0071568 | UFM1 transferase activity(GO:0071568) |
0.8 | 3.2 | GO:0016907 | G-protein coupled acetylcholine receptor activity(GO:0016907) |
0.8 | 3.2 | GO:0015183 | L-aspartate transmembrane transporter activity(GO:0015183) |
0.7 | 2.9 | GO:0015410 | manganese-transporting ATPase activity(GO:0015410) |
0.7 | 2.9 | GO:0001847 | opsonin receptor activity(GO:0001847) |
0.7 | 4.3 | GO:0015018 | galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018) |
0.7 | 3.5 | GO:0030942 | endoplasmic reticulum signal peptide binding(GO:0030942) |
0.7 | 21.0 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
0.7 | 6.1 | GO:0048185 | activin binding(GO:0048185) |
0.7 | 2.7 | GO:0008073 | ornithine decarboxylase inhibitor activity(GO:0008073) |
0.7 | 5.3 | GO:0035033 | histone deacetylase regulator activity(GO:0035033) |
0.7 | 1.3 | GO:0035373 | chondroitin sulfate proteoglycan binding(GO:0035373) |
0.6 | 3.2 | GO:0004105 | choline-phosphate cytidylyltransferase activity(GO:0004105) |
0.6 | 2.5 | GO:0050733 | RS domain binding(GO:0050733) |
0.6 | 1.9 | GO:0070140 | isopeptidase activity(GO:0070122) ubiquitin-like protein-specific isopeptidase activity(GO:0070138) SUMO-specific isopeptidase activity(GO:0070140) |
0.6 | 4.2 | GO:0031749 | D2 dopamine receptor binding(GO:0031749) |
0.6 | 24.4 | GO:0004683 | calmodulin-dependent protein kinase activity(GO:0004683) |
0.6 | 3.0 | GO:0033188 | sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493) |
0.6 | 17.2 | GO:0019707 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
0.6 | 13.0 | GO:0031489 | myosin V binding(GO:0031489) |
0.6 | 4.0 | GO:0001226 | RNA polymerase II transcription corepressor binding(GO:0001226) |
0.6 | 58.7 | GO:0004860 | protein kinase inhibitor activity(GO:0004860) |
0.6 | 5.6 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
0.6 | 14.5 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
0.6 | 3.3 | GO:0004726 | non-membrane spanning protein tyrosine phosphatase activity(GO:0004726) |
0.6 | 1.7 | GO:0001565 | phorbol ester receptor activity(GO:0001565) non-kinase phorbol ester receptor activity(GO:0001566) |
0.5 | 68.1 | GO:0005516 | calmodulin binding(GO:0005516) |
0.5 | 56.9 | GO:0005057 | receptor signaling protein activity(GO:0005057) |
0.5 | 4.2 | GO:0043560 | insulin receptor substrate binding(GO:0043560) |
0.5 | 26.0 | GO:0005262 | calcium channel activity(GO:0005262) |
0.5 | 2.6 | GO:0052833 | inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834) |
0.5 | 10.2 | GO:0048027 | mRNA 5'-UTR binding(GO:0048027) |
0.5 | 89.4 | GO:0004386 | helicase activity(GO:0004386) |
0.5 | 55.0 | GO:0004725 | protein tyrosine phosphatase activity(GO:0004725) |
0.5 | 4.4 | GO:0001972 | retinoic acid binding(GO:0001972) |
0.5 | 4.3 | GO:0030274 | LIM domain binding(GO:0030274) |
0.5 | 3.3 | GO:0036402 | proteasome-activating ATPase activity(GO:0036402) |
0.5 | 6.9 | GO:0005172 | vascular endothelial growth factor receptor binding(GO:0005172) |
0.5 | 7.3 | GO:0034237 | protein kinase A regulatory subunit binding(GO:0034237) |
0.5 | 5.0 | GO:0017166 | vinculin binding(GO:0017166) |
0.5 | 14.2 | GO:0035035 | histone acetyltransferase binding(GO:0035035) |
0.5 | 1.4 | GO:0008392 | arachidonic acid epoxygenase activity(GO:0008392) |
0.5 | 1.8 | GO:0086080 | protein binding involved in heterotypic cell-cell adhesion(GO:0086080) |
0.4 | 1.3 | GO:0043758 | acetate-CoA ligase (ADP-forming) activity(GO:0043758) |
0.4 | 4.3 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
0.4 | 5.5 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
0.4 | 3.3 | GO:0008429 | phosphatidylethanolamine binding(GO:0008429) |
0.4 | 12.1 | GO:0017091 | AU-rich element binding(GO:0017091) |
0.4 | 0.8 | GO:0031798 | type 1 metabotropic glutamate receptor binding(GO:0031798) |
0.4 | 3.6 | GO:0003873 | 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331) |
0.4 | 2.0 | GO:0008865 | fructokinase activity(GO:0008865) mannokinase activity(GO:0019158) |
0.4 | 2.8 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
0.4 | 2.3 | GO:0008321 | Ral guanyl-nucleotide exchange factor activity(GO:0008321) |
0.4 | 2.3 | GO:0004984 | olfactory receptor activity(GO:0004984) |
0.4 | 17.1 | GO:0004693 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) |
0.4 | 2.7 | GO:0005112 | Notch binding(GO:0005112) |
0.4 | 1.9 | GO:0034056 | estrogen response element binding(GO:0034056) |
0.4 | 7.3 | GO:0042805 | actinin binding(GO:0042805) |
0.4 | 3.8 | GO:0015197 | peptide transporter activity(GO:0015197) |
0.4 | 82.1 | GO:0008017 | microtubule binding(GO:0008017) |
0.4 | 1.1 | GO:0048019 | receptor antagonist activity(GO:0048019) |
0.3 | 9.0 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
0.3 | 1.0 | GO:0016716 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716) |
0.3 | 3.4 | GO:0031543 | peptidyl-proline dioxygenase activity(GO:0031543) |
0.3 | 3.4 | GO:0022848 | acetylcholine-gated cation channel activity(GO:0022848) |
0.3 | 5.1 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
0.3 | 10.8 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
0.3 | 3.0 | GO:0004571 | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) |
0.3 | 6.0 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
0.3 | 2.6 | GO:0016500 | protein-hormone receptor activity(GO:0016500) |
0.3 | 3.3 | GO:0030296 | protein tyrosine kinase activator activity(GO:0030296) |
0.3 | 2.6 | GO:0003993 | acid phosphatase activity(GO:0003993) |
0.3 | 11.0 | GO:0001786 | phosphatidylserine binding(GO:0001786) |
0.3 | 3.8 | GO:0004000 | adenosine deaminase activity(GO:0004000) |
0.3 | 0.6 | GO:0061665 | SUMO ligase activity(GO:0061665) |
0.3 | 0.6 | GO:0070052 | collagen V binding(GO:0070052) |
0.3 | 0.9 | GO:0016174 | NAD(P)H oxidase activity(GO:0016174) |
0.3 | 9.4 | GO:0048365 | Rac GTPase binding(GO:0048365) |
0.3 | 2.2 | GO:0004118 | cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) |
0.3 | 1.5 | GO:0045499 | chemorepellent activity(GO:0045499) |
0.3 | 3.6 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
0.3 | 3.3 | GO:0008526 | phosphatidylinositol transporter activity(GO:0008526) |
0.3 | 5.0 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) |
0.3 | 7.0 | GO:0042287 | MHC protein binding(GO:0042287) |
0.3 | 2.3 | GO:0005375 | copper ion transmembrane transporter activity(GO:0005375) |
0.3 | 5.6 | GO:0017056 | structural constituent of nuclear pore(GO:0017056) |
0.3 | 11.0 | GO:0019894 | kinesin binding(GO:0019894) |
0.3 | 11.2 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
0.3 | 1.4 | GO:0048248 | CXCR3 chemokine receptor binding(GO:0048248) |
0.3 | 3.0 | GO:0005242 | inward rectifier potassium channel activity(GO:0005242) |
0.3 | 0.8 | GO:0086077 | gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077) |
0.3 | 1.9 | GO:1990247 | N6-methyladenosine-containing RNA binding(GO:1990247) |
0.3 | 6.6 | GO:0008327 | methyl-CpG binding(GO:0008327) |
0.3 | 1.3 | GO:0043423 | 3-phosphoinositide-dependent protein kinase binding(GO:0043423) |
0.3 | 21.3 | GO:0030674 | protein binding, bridging(GO:0030674) |
0.3 | 1.5 | GO:0070579 | methylcytosine dioxygenase activity(GO:0070579) |
0.3 | 65.3 | GO:0005096 | GTPase activator activity(GO:0005096) |
0.3 | 3.6 | GO:0005537 | mannose binding(GO:0005537) |
0.3 | 1.5 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
0.3 | 5.3 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
0.2 | 4.4 | GO:0050681 | androgen receptor binding(GO:0050681) |
0.2 | 3.1 | GO:0008143 | poly(A) binding(GO:0008143) |
0.2 | 12.3 | GO:0015631 | tubulin binding(GO:0015631) |
0.2 | 3.3 | GO:0032454 | histone demethylase activity (H3-K9 specific)(GO:0032454) |
0.2 | 1.9 | GO:0004970 | ionotropic glutamate receptor activity(GO:0004970) |
0.2 | 5.2 | GO:0050750 | low-density lipoprotein particle receptor binding(GO:0050750) |
0.2 | 70.5 | GO:0004674 | protein serine/threonine kinase activity(GO:0004674) |
0.2 | 39.8 | GO:0042277 | peptide binding(GO:0042277) |
0.2 | 13.4 | GO:0017137 | Rab GTPase binding(GO:0017137) |
0.2 | 1.5 | GO:0031419 | cobalamin binding(GO:0031419) |
0.2 | 1.7 | GO:0008417 | fucosyltransferase activity(GO:0008417) |
0.2 | 8.5 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
0.2 | 5.4 | GO:0008009 | chemokine activity(GO:0008009) |
0.2 | 145.4 | GO:0042803 | protein homodimerization activity(GO:0042803) |
0.2 | 2.2 | GO:0008641 | small protein activating enzyme activity(GO:0008641) |
0.2 | 1.8 | GO:0015347 | sodium-independent organic anion transmembrane transporter activity(GO:0015347) |
0.2 | 4.1 | GO:0000062 | fatty-acyl-CoA binding(GO:0000062) |
0.2 | 2.5 | GO:0010314 | phosphatidylinositol-5-phosphate binding(GO:0010314) |
0.2 | 1.4 | GO:0003747 | translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079) |
0.2 | 0.8 | GO:0015245 | fatty acid transporter activity(GO:0015245) |
0.2 | 0.8 | GO:1990226 | histone methyltransferase binding(GO:1990226) |
0.2 | 12.5 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
0.2 | 1.6 | GO:0008474 | palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599) |
0.2 | 3.3 | GO:0005507 | copper ion binding(GO:0005507) |
0.2 | 1.8 | GO:0008553 | hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553) |
0.2 | 0.8 | GO:1990380 | Lys48-specific deubiquitinase activity(GO:1990380) |
0.1 | 1.3 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
0.1 | 0.9 | GO:0000990 | transcription factor activity, core RNA polymerase binding(GO:0000990) |
0.1 | 0.9 | GO:0001515 | opioid peptide activity(GO:0001515) |
0.1 | 1.0 | GO:0090599 | alpha-glucosidase activity(GO:0090599) |
0.1 | 1.6 | GO:0005044 | scavenger receptor activity(GO:0005044) |
0.1 | 4.6 | GO:0015485 | cholesterol binding(GO:0015485) |
0.1 | 5.6 | GO:0008081 | phosphoric diester hydrolase activity(GO:0008081) |
0.1 | 1.6 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
0.1 | 2.3 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
0.1 | 0.3 | GO:0051378 | serotonin binding(GO:0051378) |
0.1 | 1.2 | GO:0033130 | acetylcholine receptor binding(GO:0033130) |
0.1 | 17.6 | GO:0044822 | mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822) |
0.1 | 0.5 | GO:0032896 | palmitoyl-CoA 9-desaturase activity(GO:0032896) |
0.1 | 2.6 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
0.1 | 21.8 | GO:0031625 | ubiquitin protein ligase binding(GO:0031625) |
0.1 | 0.6 | GO:0015643 | toxic substance binding(GO:0015643) |
0.1 | 3.1 | GO:0001671 | ATPase activator activity(GO:0001671) |
0.1 | 1.6 | GO:0008536 | Ran GTPase binding(GO:0008536) |
0.1 | 1.4 | GO:0005035 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
0.1 | 2.8 | GO:0030515 | snoRNA binding(GO:0030515) |
0.1 | 3.6 | GO:0032947 | protein complex scaffold(GO:0032947) |
0.1 | 6.6 | GO:0004197 | cysteine-type endopeptidase activity(GO:0004197) |
0.1 | 0.5 | GO:0001010 | transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010) |
0.1 | 3.4 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
0.1 | 0.6 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
0.1 | 0.7 | GO:0015181 | arginine transmembrane transporter activity(GO:0015181) |
0.1 | 1.0 | GO:0036442 | hydrogen-exporting ATPase activity(GO:0036442) proton-transporting ATPase activity, rotational mechanism(GO:0046961) |
0.1 | 1.3 | GO:0008253 | 5'-nucleotidase activity(GO:0008253) |
0.1 | 0.5 | GO:0003876 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
0.1 | 1.9 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
0.1 | 0.3 | GO:0051377 | mannose-ethanolamine phosphotransferase activity(GO:0051377) |
0.1 | 5.8 | GO:0030246 | carbohydrate binding(GO:0030246) |
0.1 | 0.2 | GO:0008823 | cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851) |
0.1 | 1.1 | GO:0070064 | proline-rich region binding(GO:0070064) |
0.1 | 1.7 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
0.1 | 0.4 | GO:0015379 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
0.1 | 4.2 | GO:0016779 | nucleotidyltransferase activity(GO:0016779) |
0.0 | 1.1 | GO:0005351 | sugar:proton symporter activity(GO:0005351) |
0.0 | 2.5 | GO:0051219 | phosphoprotein binding(GO:0051219) |
0.0 | 1.8 | GO:0008374 | O-acyltransferase activity(GO:0008374) |
0.0 | 3.1 | GO:0008236 | serine-type peptidase activity(GO:0008236) |
0.0 | 0.1 | GO:0042284 | sphingolipid delta-4 desaturase activity(GO:0042284) |
0.0 | 0.2 | GO:0097371 | MDM2/MDM4 family protein binding(GO:0097371) |
0.0 | 0.1 | GO:0004849 | uridine kinase activity(GO:0004849) |
0.0 | 0.2 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
0.0 | 0.1 | GO:0004035 | alkaline phosphatase activity(GO:0004035) |
0.0 | 0.4 | GO:0050699 | WW domain binding(GO:0050699) |
0.0 | 0.3 | GO:0017022 | myosin binding(GO:0017022) |
0.0 | 0.1 | GO:0004806 | triglyceride lipase activity(GO:0004806) |
0.0 | 0.3 | GO:0048306 | calcium-dependent protein binding(GO:0048306) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.1 | 95.8 | PID_MAPK_TRK_PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
1.6 | 88.5 | PID_REELIN_PATHWAY | Reelin signaling pathway |
1.3 | 2.6 | PID_ER_NONGENOMIC_PATHWAY | Plasma membrane estrogen receptor signaling |
1.0 | 40.5 | SIG_CD40PATHWAYMAP | Genes related to CD40 signaling |
1.0 | 32.0 | PID_EPHA_FWDPATHWAY | EPHA forward signaling |
0.9 | 32.6 | PID_ALK1_PATHWAY | ALK1 signaling events |
0.9 | 14.5 | PID_NCADHERIN_PATHWAY | N-cadherin signaling events |
0.9 | 21.2 | PID_TOLL_ENDOGENOUS_PATHWAY | Endogenous TLR signaling |
0.9 | 23.0 | PID_LIS1_PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
0.8 | 60.3 | PID_LKB1_PATHWAY | LKB1 signaling events |
0.8 | 78.0 | PID_CMYB_PATHWAY | C-MYB transcription factor network |
0.8 | 13.0 | SA_PTEN_PATHWAY | PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate. |
0.8 | 17.6 | PID_EPHRINB_REV_PATHWAY | Ephrin B reverse signaling |
0.8 | 32.4 | PID_ERBB1_INTERNALIZATION_PATHWAY | Internalization of ErbB1 |
0.7 | 8.2 | PID_RHODOPSIN_PATHWAY | Visual signal transduction: Rods |
0.7 | 19.5 | ST_ERK1_ERK2_MAPK_PATHWAY | ERK1/ERK2 MAPK Pathway |
0.7 | 17.8 | PID_IL3_PATHWAY | IL3-mediated signaling events |
0.7 | 26.9 | PID_TRKR_PATHWAY | Neurotrophic factor-mediated Trk receptor signaling |
0.6 | 9.5 | PID_ERB_GENOMIC_PATHWAY | Validated nuclear estrogen receptor beta network |
0.5 | 15.6 | PID_KIT_PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
0.5 | 22.9 | PID_FGF_PATHWAY | FGF signaling pathway |
0.5 | 26.1 | PID_RAC1_REG_PATHWAY | Regulation of RAC1 activity |
0.5 | 10.7 | PID_ANGIOPOIETIN_RECEPTOR_PATHWAY | Angiopoietin receptor Tie2-mediated signaling |
0.5 | 4.3 | PID_UPA_UPAR_PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
0.5 | 17.5 | PID_BMP_PATHWAY | BMP receptor signaling |
0.5 | 15.8 | PID_ARF6_TRAFFICKING_PATHWAY | Arf6 trafficking events |
0.5 | 10.6 | PID_MYC_PATHWAY | C-MYC pathway |
0.5 | 5.0 | PID_RANBP2_PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
0.4 | 11.2 | PID_IL4_2PATHWAY | IL4-mediated signaling events |
0.4 | 11.2 | PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY | Signaling mediated by p38-alpha and p38-beta |
0.4 | 14.8 | PID_TAP63_PATHWAY | Validated transcriptional targets of TAp63 isoforms |
0.4 | 16.1 | PID_NFAT_TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
0.4 | 5.5 | ST_GRANULE_CELL_SURVIVAL_PATHWAY | Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway. |
0.4 | 9.5 | ST_WNT_BETA_CATENIN_PATHWAY | Wnt/beta-catenin Pathway |
0.4 | 7.0 | ST_G_ALPHA_I_PATHWAY | G alpha i Pathway |
0.4 | 3.3 | PID_SYNDECAN_2_PATHWAY | Syndecan-2-mediated signaling events |
0.4 | 22.9 | PID_AR_PATHWAY | Coregulation of Androgen receptor activity |
0.3 | 10.7 | PID_TNF_PATHWAY | TNF receptor signaling pathway |
0.3 | 20.5 | PID_PDGFRB_PATHWAY | PDGFR-beta signaling pathway |
0.3 | 3.8 | PID_ERBB2_ERBB3_PATHWAY | ErbB2/ErbB3 signaling events |
0.3 | 1.3 | PID_ERBB_NETWORK_PATHWAY | ErbB receptor signaling network |
0.3 | 1.9 | PID_IL2_PI3K_PATHWAY | IL2 signaling events mediated by PI3K |
0.3 | 10.7 | PID_REG_GR_PATHWAY | Glucocorticoid receptor regulatory network |
0.2 | 3.6 | PID_TCPTP_PATHWAY | Signaling events mediated by TCPTP |
0.2 | 2.4 | PID_AR_NONGENOMIC_PATHWAY | Nongenotropic Androgen signaling |
0.2 | 8.7 | PID_RHOA_REG_PATHWAY | Regulation of RhoA activity |
0.2 | 1.3 | PID_P38_GAMMA_DELTA_PATHWAY | Signaling mediated by p38-gamma and p38-delta |
0.2 | 8.3 | ST_INTEGRIN_SIGNALING_PATHWAY | Integrin Signaling Pathway |
0.2 | 4.6 | PID_P75_NTR_PATHWAY | p75(NTR)-mediated signaling |
0.2 | 5.5 | PID_HIF2PATHWAY | HIF-2-alpha transcription factor network |
0.2 | 1.7 | ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY | PI3K Pathway |
0.2 | 0.3 | PID_ERBB1_RECEPTOR_PROXIMAL_PATHWAY | EGF receptor (ErbB1) signaling pathway |
0.1 | 1.7 | PID_LPA4_PATHWAY | LPA4-mediated signaling events |
0.1 | 4.3 | PID_TGFBR_PATHWAY | TGF-beta receptor signaling |
0.1 | 1.0 | PID_NECTIN_PATHWAY | Nectin adhesion pathway |
0.1 | 15.0 | NABA_ECM_REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
0.1 | 1.4 | PID_ERBB4_PATHWAY | ErbB4 signaling events |
0.1 | 0.7 | PID_IL12_STAT4_PATHWAY | IL12 signaling mediated by STAT4 |
0.1 | 1.3 | PID_AJDISS_2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
0.1 | 0.3 | PID_PTP1B_PATHWAY | Signaling events mediated by PTP1B |
0.0 | 0.5 | PID_LYSOPHOSPHOLIPID_PATHWAY | LPA receptor mediated events |
0.0 | 0.6 | PID_CIRCADIAN_PATHWAY | Circadian rhythm pathway |
0.0 | 1.4 | PID_MYC_REPRESS_PATHWAY | Validated targets of C-MYC transcriptional repression |
0.0 | 5.0 | NABA_SECRETED_FACTORS | Genes encoding secreted soluble factors |
0.0 | 2.4 | PID_P53_DOWNSTREAM_PATHWAY | Direct p53 effectors |
0.0 | 0.4 | PID_RAC1_PATHWAY | RAC1 signaling pathway |
0.0 | 0.6 | PID_RB_1PATHWAY | Regulation of retinoblastoma protein |
0.0 | 0.9 | PID_P53_REGULATION_PATHWAY | p53 pathway |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
9.2 | 36.7 | REACTOME_GLYCOPROTEIN_HORMONES | Genes involved in Glycoprotein hormones |
5.2 | 52.5 | REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE | Genes involved in Acetylcholine Neurotransmitter Release Cycle |
3.6 | 69.2 | REACTOME_LIGAND_GATED_ION_CHANNEL_TRANSPORT | Genes involved in Ligand-gated ion channel transport |
3.3 | 104.4 | REACTOME_ERK_MAPK_TARGETS | Genes involved in ERK/MAPK targets |
3.1 | 117.7 | REACTOME_DARPP_32_EVENTS | Genes involved in DARPP-32 events |
3.0 | 107.9 | REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
2.9 | 77.8 | REACTOME_UNBLOCKING_OF_NMDA_RECEPTOR_GLUTAMATE_BINDING_AND_ACTIVATION | Genes involved in Unblocking of NMDA receptor, glutamate binding and activation |
2.4 | 4.8 | REACTOME_SIGNALLING_BY_NGF | Genes involved in Signalling by NGF |
1.8 | 63.8 | REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS | Genes involved in Adherens junctions interactions |
1.8 | 23.6 | REACTOME_PLATELET_CALCIUM_HOMEOSTASIS | Genes involved in Platelet calcium homeostasis |
1.5 | 20.9 | REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
1.5 | 33.8 | REACTOME_TIE2_SIGNALING | Genes involved in Tie2 Signaling |
1.4 | 15.4 | REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE | Genes involved in Glutamate Neurotransmitter Release Cycle |
1.4 | 33.1 | REACTOME_CA_DEPENDENT_EVENTS | Genes involved in Ca-dependent events |
1.1 | 14.7 | REACTOME_NEPHRIN_INTERACTIONS | Genes involved in Nephrin interactions |
1.1 | 38.9 | REACTOME_LYSOSOME_VESICLE_BIOGENESIS | Genes involved in Lysosome Vesicle Biogenesis |
1.0 | 19.7 | REACTOME_N_GLYCAN_ANTENNAE_ELONGATION | Genes involved in N-Glycan antennae elongation |
1.0 | 73.2 | REACTOME_L1CAM_INTERACTIONS | Genes involved in L1CAM interactions |
0.9 | 15.0 | REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS | Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis |
0.9 | 34.8 | REACTOME_HS_GAG_BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
0.9 | 21.5 | REACTOME_EGFR_DOWNREGULATION | Genes involved in EGFR downregulation |
0.8 | 7.5 | REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
0.8 | 18.2 | REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING | Genes involved in DCC mediated attractive signaling |
0.8 | 23.1 | REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA | Genes involved in Circadian Repression of Expression by REV-ERBA |
0.8 | 2.4 | REACTOME_HORMONE_LIGAND_BINDING_RECEPTORS | Genes involved in Hormone ligand-binding receptors |
0.8 | 4.0 | REACTOME_VIF_MEDIATED_DEGRADATION_OF_APOBEC3G | Genes involved in Vif-mediated degradation of APOBEC3G |
0.7 | 22.3 | REACTOME_SIGNALING_BY_BMP | Genes involved in Signaling by BMP |
0.7 | 7.9 | REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
0.7 | 10.5 | REACTOME_HYALURONAN_METABOLISM | Genes involved in Hyaluronan metabolism |
0.7 | 3.5 | REACTOME_DSCAM_INTERACTIONS | Genes involved in DSCAM interactions |
0.7 | 8.5 | REACTOME_AMINE_LIGAND_BINDING_RECEPTORS | Genes involved in Amine ligand-binding receptors |
0.6 | 15.6 | REACTOME_OTHER_SEMAPHORIN_INTERACTIONS | Genes involved in Other semaphorin interactions |
0.6 | 4.4 | REACTOME_SIGNALING_BY_ACTIVATED_POINT_MUTANTS_OF_FGFR1 | Genes involved in Signaling by activated point mutants of FGFR1 |
0.6 | 7.1 | REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE | Genes involved in Beta-catenin phosphorylation cascade |
0.6 | 43.9 | REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK | Genes involved in NRAGE signals death through JNK |
0.6 | 4.0 | REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING | Genes involved in Sema4D in semaphorin signaling |
0.5 | 13.2 | REACTOME_TRANSPORT_TO_THE_GOLGI_AND_SUBSEQUENT_MODIFICATION | Genes involved in Transport to the Golgi and subsequent modification |
0.5 | 4.0 | REACTOME_ACTIVATION_OF_RAC | Genes involved in Activation of Rac |
0.5 | 13.2 | REACTOME_RNA_POL_III_TRANSCRIPTION_TERMINATION | Genes involved in RNA Polymerase III Transcription Termination |
0.5 | 18.9 | REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS | Genes involved in Voltage gated Potassium channels |
0.5 | 7.6 | REACTOME_METABOLISM_OF_POLYAMINES | Genes involved in Metabolism of polyamines |
0.5 | 16.9 | REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS | Genes involved in O-linked glycosylation of mucins |
0.5 | 4.6 | REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS | Genes involved in Role of DCC in regulating apoptosis |
0.5 | 42.8 | REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
0.4 | 2.7 | REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE_ODC | Genes involved in Regulation of ornithine decarboxylase (ODC) |
0.4 | 3.9 | REACTOME_TRYPTOPHAN_CATABOLISM | Genes involved in Tryptophan catabolism |
0.4 | 3.4 | REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS | Genes involved in Presynaptic nicotinic acetylcholine receptors |
0.4 | 11.9 | REACTOME_DEADENYLATION_OF_MRNA | Genes involved in Deadenylation of mRNA |
0.4 | 6.3 | REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
0.3 | 2.7 | REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
0.3 | 4.6 | REACTOME_REGULATION_OF_KIT_SIGNALING | Genes involved in Regulation of KIT signaling |
0.3 | 3.6 | REACTOME_ACTIVATION_OF_CHAPERONES_BY_ATF6_ALPHA | Genes involved in Activation of Chaperones by ATF6-alpha |
0.3 | 4.2 | REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
0.3 | 2.5 | REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
0.3 | 34.6 | REACTOME_G_ALPHA_I_SIGNALLING_EVENTS | Genes involved in G alpha (i) signalling events |
0.3 | 6.8 | REACTOME_ENOS_ACTIVATION_AND_REGULATION | Genes involved in eNOS activation and regulation |
0.3 | 11.5 | REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
0.2 | 3.3 | REACTOME_FORMATION_OF_TRANSCRIPTION_COUPLED_NER_TC_NER_REPAIR_COMPLEX | Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex |
0.2 | 5.7 | REACTOME_SYNTHESIS_OF_PC | Genes involved in Synthesis of PC |
0.2 | 3.2 | REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION | Genes involved in Cyclin A/B1 associated events during G2/M transition |
0.2 | 1.8 | REACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION | Genes involved in Sema3A PAK dependent Axon repulsion |
0.2 | 13.1 | REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
0.2 | 2.5 | REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
0.2 | 0.8 | REACTOME_DESTABILIZATION_OF_MRNA_BY_AUF1_HNRNP_D0 | Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0) |
0.2 | 3.6 | REACTOME_REGULATORY_RNA_PATHWAYS | Genes involved in Regulatory RNA pathways |
0.2 | 3.6 | REACTOME_SIGNALING_BY_ROBO_RECEPTOR | Genes involved in Signaling by Robo receptor |
0.1 | 1.3 | REACTOME_PYRIMIDINE_CATABOLISM | Genes involved in Pyrimidine catabolism |
0.1 | 4.7 | REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
0.1 | 2.3 | REACTOME_ZINC_TRANSPORTERS | Genes involved in Zinc transporters |
0.1 | 6.0 | REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING | Genes involved in p75 NTR receptor-mediated signalling |
0.1 | 0.3 | REACTOME_NOREPINEPHRINE_NEUROTRANSMITTER_RELEASE_CYCLE | Genes involved in Norepinephrine Neurotransmitter Release Cycle |
0.1 | 3.9 | REACTOME_ION_CHANNEL_TRANSPORT | Genes involved in Ion channel transport |
0.1 | 1.0 | REACTOME_SHC1_EVENTS_IN_ERBB4_SIGNALING | Genes involved in SHC1 events in ERBB4 signaling |
0.1 | 1.9 | REACTOME_METABOLISM_OF_STEROID_HORMONES_AND_VITAMINS_A_AND_D | Genes involved in Metabolism of steroid hormones and vitamins A and D |
0.1 | 2.8 | REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS | Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis |
0.1 | 1.3 | REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE | Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle |
0.1 | 9.6 | REACTOME_SIGNALING_BY_RHO_GTPASES | Genes involved in Signaling by Rho GTPases |
0.1 | 0.8 | REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol |
0.1 | 1.2 | REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
0.1 | 6.0 | REACTOME_CYCLIN_E_ASSOCIATED_EVENTS_DURING_G1_S_TRANSITION_ | Genes involved in Cyclin E associated events during G1/S transition |
0.1 | 1.9 | REACTOME_SIGNALING_BY_FGFR1_MUTANTS | Genes involved in Signaling by FGFR1 mutants |
0.1 | 0.9 | REACTOME_PROLONGED_ERK_ACTIVATION_EVENTS | Genes involved in Prolonged ERK activation events |
0.1 | 4.7 | REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
0.1 | 1.4 | REACTOME_CGMP_EFFECTS | Genes involved in cGMP effects |
0.1 | 0.6 | REACTOME_REGULATION_OF_IFNG_SIGNALING | Genes involved in Regulation of IFNG signaling |
0.1 | 0.6 | REACTOME_GLUCOSE_TRANSPORT | Genes involved in Glucose transport |
0.1 | 0.8 | REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 | Genes involved in Nuclear signaling by ERBB4 |
0.1 | 1.5 | REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS | Genes involved in Effects of PIP2 hydrolysis |
0.0 | 0.8 | REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS | Genes involved in Glycogen breakdown (glycogenolysis) |
0.0 | 0.3 | REACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT | Genes involved in Initial triggering of complement |
0.0 | 0.4 | REACTOME_SIGNALING_BY_EGFR_IN_CANCER | Genes involved in Signaling by EGFR in Cancer |
0.0 | 1.9 | REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION | Genes involved in MHC class II antigen presentation |
0.0 | 1.1 | REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES | Genes involved in Transport of vitamins, nucleosides, and related molecules |
0.0 | 0.3 | REACTOME_PURINE_SALVAGE | Genes involved in Purine salvage |
0.0 | 0.8 | REACTOME_NGF_SIGNALLING_VIA_TRKA_FROM_THE_PLASMA_MEMBRANE | Genes involved in NGF signalling via TRKA from the plasma membrane |
0.0 | 0.4 | REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
0.0 | 0.3 | REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI | Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) |
0.0 | 0.1 | REACTOME_CRMPS_IN_SEMA3A_SIGNALING | Genes involved in CRMPs in Sema3A signaling |
0.0 | 0.0 | REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION | Genes involved in Influenza Viral RNA Transcription and Replication |