Motif ID: Hoxb7

Z-value: 3.443


Transcription factors associated with Hoxb7:

Gene SymbolEntrez IDGene Name
Hoxb7 ENSMUSG00000038721.8 Hoxb7



Activity profile for motif Hoxb7.

activity profile for motif Hoxb7


Sorted Z-values histogram for motif Hoxb7

Sorted Z-values for motif Hoxb7



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxb7

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr13_+_83504032 70.520 ENSMUST00000163888.1
ENSMUST00000005722.7
Mef2c

myocyte enhancer factor 2C

chr12_-_31713873 61.984 ENSMUST00000057783.4
ENSMUST00000174480.2
ENSMUST00000176710.1
Gpr22


G protein-coupled receptor 22


chrX_-_43167817 54.827 ENSMUST00000115058.1
ENSMUST00000115059.1
Tenm1

teneurin transmembrane protein 1

chr4_+_13751297 47.321 ENSMUST00000105566.2
Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr15_+_21111452 43.805 ENSMUST00000075132.6
Cdh12
cadherin 12
chr6_-_136171722 39.966 ENSMUST00000053880.6
Grin2b
glutamate receptor, ionotropic, NMDA2B (epsilon 2)
chr4_+_102589687 39.093 ENSMUST00000097949.4
ENSMUST00000106901.1
Pde4b

phosphodiesterase 4B, cAMP specific

chr2_+_65930117 32.663 ENSMUST00000176109.1
Csrnp3
cysteine-serine-rich nuclear protein 3
chr9_-_112187766 31.998 ENSMUST00000111872.2
ENSMUST00000164754.2
Arpp21

cyclic AMP-regulated phosphoprotein, 21

chr10_-_64090265 31.299 ENSMUST00000105439.1
Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr6_+_15196949 31.020 ENSMUST00000151301.1
ENSMUST00000131414.1
ENSMUST00000140557.1
ENSMUST00000115469.1
Foxp2



forkhead box P2



chr6_-_144209558 29.581 ENSMUST00000111749.1
ENSMUST00000170367.2
Sox5

SRY-box containing gene 5

chr19_+_26605106 29.514 ENSMUST00000025862.7
ENSMUST00000176030.1
Smarca2

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2

chr6_-_144209471 29.357 ENSMUST00000038815.7
Sox5
SRY-box containing gene 5
chr8_-_109251698 29.059 ENSMUST00000079189.3
4922502B01Rik
RIKEN cDNA 4922502B01 gene
chr6_-_144209448 28.289 ENSMUST00000077160.5
Sox5
SRY-box containing gene 5
chr17_-_90088343 27.092 ENSMUST00000173917.1
Nrxn1
neurexin I
chr11_-_30198232 26.939 ENSMUST00000102838.3
Sptbn1
spectrin beta, non-erythrocytic 1
chr6_-_13839916 26.910 ENSMUST00000060442.7
Gpr85
G protein-coupled receptor 85
chrX_-_43274786 25.869 ENSMUST00000016294.7
Tenm1
teneurin transmembrane protein 1
chr10_-_64090241 25.564 ENSMUST00000133588.1
Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr2_-_7395879 25.434 ENSMUST00000182404.1
Celf2
CUGBP, Elav-like family member 2
chr3_+_67892189 25.409 ENSMUST00000063263.3
Iqcj
IQ motif containing J
chr6_+_96113146 24.836 ENSMUST00000122120.1
Fam19a1
family with sequence similarity 19, member A1
chr15_+_92597104 24.761 ENSMUST00000035399.8
Pdzrn4
PDZ domain containing RING finger 4
chr14_-_93888732 24.501 ENSMUST00000068992.2
Pcdh9
protocadherin 9
chr4_-_14621805 24.143 ENSMUST00000042221.7
Slc26a7
solute carrier family 26, member 7
chr13_+_16014457 24.132 ENSMUST00000164993.1
Inhba
inhibin beta-A
chr2_-_7396192 23.889 ENSMUST00000137733.2
Celf2
CUGBP, Elav-like family member 2
chr3_-_26133734 23.300 ENSMUST00000108308.3
ENSMUST00000075054.4
Nlgn1

neuroligin 1

chr9_-_112187898 23.075 ENSMUST00000178410.1
ENSMUST00000172380.3
Arpp21

cyclic AMP-regulated phosphoprotein, 21

chr1_-_126830632 22.894 ENSMUST00000112583.1
ENSMUST00000094609.3
Nckap5

NCK-associated protein 5

chr3_-_141982224 22.780 ENSMUST00000029948.8
Bmpr1b
bone morphogenetic protein receptor, type 1B
chr15_-_48791933 22.707 ENSMUST00000160658.1
ENSMUST00000100670.3
ENSMUST00000162830.1
Csmd3


CUB and Sushi multiple domains 3


chr2_+_65620829 22.530 ENSMUST00000028377.7
Scn2a1
sodium channel, voltage-gated, type II, alpha 1
chr1_+_66321708 21.861 ENSMUST00000114013.1
Map2
microtubule-associated protein 2
chr2_-_45112890 21.822 ENSMUST00000076836.6
Zeb2
zinc finger E-box binding homeobox 2
chr10_-_109009055 21.687 ENSMUST00000156979.1
Syt1
synaptotagmin I
chrM_+_10167 21.546 ENSMUST00000082414.1
mt-Nd4
mitochondrially encoded NADH dehydrogenase 4
chr10_+_90576252 21.411 ENSMUST00000182427.1
ENSMUST00000182053.1
ENSMUST00000182113.1
Anks1b


ankyrin repeat and sterile alpha motif domain containing 1B


chr1_+_159737510 20.964 ENSMUST00000111669.3
Tnr
tenascin R
chr1_+_34005872 20.752 ENSMUST00000182296.1
Dst
dystonin
chr19_+_26749726 20.536 ENSMUST00000175842.1
Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr2_-_7395968 20.426 ENSMUST00000002176.6
Celf2
CUGBP, Elav-like family member 2
chr2_+_37516618 19.434 ENSMUST00000065441.6
Gpr21
G protein-coupled receptor 21
chr4_-_35845204 18.942 ENSMUST00000164772.1
ENSMUST00000065173.2
Lingo2

leucine rich repeat and Ig domain containing 2

chr1_-_56969827 18.907 ENSMUST00000176759.1
Satb2
special AT-rich sequence binding protein 2
chr10_-_109010955 18.861 ENSMUST00000105276.1
ENSMUST00000064054.7
Syt1

synaptotagmin I

chr11_+_31872100 18.598 ENSMUST00000020543.6
ENSMUST00000109412.2
Cpeb4

cytoplasmic polyadenylation element binding protein 4

chr1_-_126830786 18.432 ENSMUST00000162646.1
Nckap5
NCK-associated protein 5
chr4_-_14621494 18.141 ENSMUST00000149633.1
Slc26a7
solute carrier family 26, member 7
chr19_+_26750939 18.128 ENSMUST00000175953.1
Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr9_-_29963112 18.125 ENSMUST00000075069.4
Ntm
neurotrimin
chr19_-_14597983 18.018 ENSMUST00000052011.7
Tle4
transducin-like enhancer of split 4, homolog of Drosophila E(spl)
chr3_+_55461758 17.986 ENSMUST00000070418.4
Dclk1
doublecortin-like kinase 1
chr19_-_14598031 17.898 ENSMUST00000167776.2
Tle4
transducin-like enhancer of split 4, homolog of Drosophila E(spl)
chrX_+_112615301 17.845 ENSMUST00000122805.1
Zfp711
zinc finger protein 711
chr14_-_12345847 17.783 ENSMUST00000022262.4
Fezf2
Fez family zinc finger 2
chr2_-_7081207 17.639 ENSMUST00000114923.2
ENSMUST00000182706.1
Celf2

CUGBP, Elav-like family member 2

chr1_-_56969864 17.114 ENSMUST00000177424.1
Satb2
special AT-rich sequence binding protein 2
chr2_+_96318014 17.078 ENSMUST00000135431.1
ENSMUST00000162807.2
Lrrc4c

leucine rich repeat containing 4C

chr11_-_76509419 17.044 ENSMUST00000094012.4
Abr
active BCR-related gene
chr15_-_66812593 17.012 ENSMUST00000100572.3
Sla
src-like adaptor
chrX_+_112604274 16.852 ENSMUST00000071814.6
Zfp711
zinc finger protein 711
chrM_+_7759 16.850 ENSMUST00000082407.1
ENSMUST00000082408.1
mt-Atp8
mt-Atp6
mitochondrially encoded ATP synthase 8
mitochondrially encoded ATP synthase 6
chr2_+_68104671 16.737 ENSMUST00000042456.3
B3galt1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr1_-_25228814 16.672 ENSMUST00000126626.1
Bai3
brain-specific angiogenesis inhibitor 3
chr8_+_54954728 16.641 ENSMUST00000033915.7
Gpm6a
glycoprotein m6a
chr2_-_6884940 16.633 ENSMUST00000183091.1
ENSMUST00000182851.1
Celf2

CUGBP, Elav-like family member 2

chr16_+_7069825 16.605 ENSMUST00000056416.7
Rbfox1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr11_-_37235882 16.433 ENSMUST00000102801.1
Tenm2
teneurin transmembrane protein 2
chr15_+_92161343 16.379 ENSMUST00000068378.5
Cntn1
contactin 1
chr14_-_124677089 16.287 ENSMUST00000095529.3
Fgf14
fibroblast growth factor 14
chr4_+_101507947 16.046 ENSMUST00000149047.1
ENSMUST00000106929.3
Dnajc6

DnaJ (Hsp40) homolog, subfamily C, member 6

chr2_-_7081256 15.973 ENSMUST00000183209.1
Celf2
CUGBP, Elav-like family member 2
chr19_-_57239310 15.911 ENSMUST00000111559.1
Ablim1
actin-binding LIM protein 1
chr13_+_93308006 15.887 ENSMUST00000079086.6
Homer1
homer homolog 1 (Drosophila)
chr17_-_81649607 15.709 ENSMUST00000163680.2
ENSMUST00000086538.3
ENSMUST00000163123.1
Slc8a1


solute carrier family 8 (sodium/calcium exchanger), member 1


chr10_-_45470201 15.707 ENSMUST00000079390.6
Lin28b
lin-28 homolog B (C. elegans)
chr7_+_91090697 15.590 ENSMUST00000107196.2
Dlg2
discs, large homolog 2 (Drosophila)
chr13_-_99516537 15.580 ENSMUST00000064762.4
Map1b
microtubule-associated protein 1B
chr2_-_57113053 15.463 ENSMUST00000112627.1
Nr4a2
nuclear receptor subfamily 4, group A, member 2
chr7_+_91090728 15.397 ENSMUST00000074273.3
Dlg2
discs, large homolog 2 (Drosophila)
chr9_+_32116040 15.133 ENSMUST00000174641.1
Arhgap32
Rho GTPase activating protein 32
chr10_+_99263224 15.074 ENSMUST00000020118.4
Dusp6
dual specificity phosphatase 6
chr17_+_70561739 15.035 ENSMUST00000097288.2
Dlgap1
discs, large (Drosophila) homolog-associated protein 1
chr2_-_64975762 14.858 ENSMUST00000156765.1
Grb14
growth factor receptor bound protein 14
chr6_+_15185456 14.823 ENSMUST00000115472.1
ENSMUST00000115474.1
ENSMUST00000031545.7
ENSMUST00000137628.1
Foxp2



forkhead box P2



chr1_+_179961110 14.739 ENSMUST00000076687.5
ENSMUST00000097450.3
Cdc42bpa

CDC42 binding protein kinase alpha

chr4_+_102421518 14.734 ENSMUST00000106904.2
Pde4b
phosphodiesterase 4B, cAMP specific
chr10_+_90576872 14.713 ENSMUST00000182550.1
ENSMUST00000099364.5
Anks1b

ankyrin repeat and sterile alpha motif domain containing 1B

chr11_-_42000834 14.580 ENSMUST00000070725.4
Gabrg2
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2
chr12_+_29528382 14.537 ENSMUST00000049784.9
Myt1l
myelin transcription factor 1-like
chr13_+_83573577 14.373 ENSMUST00000185052.1
Mef2c
myocyte enhancer factor 2C
chr14_-_36935560 14.303 ENSMUST00000183038.1
Ccser2
coiled-coil serine rich 2
chrM_+_7005 14.270 ENSMUST00000082405.1
mt-Co2
mitochondrially encoded cytochrome c oxidase II
chrX_-_165327376 14.196 ENSMUST00000058787.8
Glra2
glycine receptor, alpha 2 subunit
chr3_+_26331150 13.995 ENSMUST00000099182.2
A830092H15Rik
RIKEN cDNA A830092H15 gene
chr6_-_99044414 13.964 ENSMUST00000177507.1
ENSMUST00000123992.1
Foxp1

forkhead box P1

chr11_+_29463735 13.909 ENSMUST00000155854.1
Ccdc88a
coiled coil domain containing 88A
chr9_-_101198999 13.898 ENSMUST00000066773.7
Ppp2r3a
protein phosphatase 2, regulatory subunit B'', alpha
chr8_-_8639363 13.881 ENSMUST00000152698.1
Efnb2
ephrin B2
chr10_+_90576570 13.856 ENSMUST00000182786.1
ENSMUST00000182600.1
Anks1b

ankyrin repeat and sterile alpha motif domain containing 1B

chr4_-_14621669 13.708 ENSMUST00000143105.1
Slc26a7
solute carrier family 26, member 7
chr18_-_31447383 13.638 ENSMUST00000025110.3
Syt4
synaptotagmin IV
chr17_+_3397189 13.450 ENSMUST00000072156.6
Tiam2
T cell lymphoma invasion and metastasis 2
chr13_+_42681513 13.420 ENSMUST00000149235.1
Phactr1
phosphatase and actin regulator 1
chr13_-_89742244 13.417 ENSMUST00000109543.2
ENSMUST00000159337.1
ENSMUST00000159910.1
ENSMUST00000109544.2
Vcan



versican



chr15_-_93595877 13.401 ENSMUST00000048982.4
Prickle1
prickle homolog 1 (Drosophila)
chr13_-_41079628 13.285 ENSMUST00000165087.1
ENSMUST00000070193.6
Mak

male germ cell-associated kinase

chr19_-_19001099 13.211 ENSMUST00000040153.8
ENSMUST00000112828.1
Rorb

RAR-related orphan receptor beta

chr1_+_81077274 13.164 ENSMUST00000068275.5
ENSMUST00000113494.2
Nyap2

neuronal tyrosine-phophorylated phosphoinositide 3-kinase adaptor 2

chr1_+_66322102 13.128 ENSMUST00000123647.1
Map2
microtubule-associated protein 2
chr1_+_34121250 13.128 ENSMUST00000183006.1
Dst
dystonin
chr9_-_49798905 13.110 ENSMUST00000114476.2
Ncam1
neural cell adhesion molecule 1
chr15_-_13173607 13.035 ENSMUST00000036439.4
Cdh6
cadherin 6
chr10_-_6980376 13.026 ENSMUST00000105617.1
Ipcef1
interaction protein for cytohesin exchange factors 1
chr2_-_45113255 12.830 ENSMUST00000068415.4
ENSMUST00000127520.1
Zeb2

zinc finger E-box binding homeobox 2

chr5_+_107497762 12.808 ENSMUST00000152474.1
ENSMUST00000060553.7
A830010M20Rik

RIKEN cDNA A830010M20 gene

chr3_+_125404072 12.800 ENSMUST00000173932.1
Ndst4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr13_+_42680565 12.785 ENSMUST00000128646.1
Phactr1
phosphatase and actin regulator 1
chr2_-_80128834 12.752 ENSMUST00000102654.4
ENSMUST00000102655.3
Pde1a

phosphodiesterase 1A, calmodulin-dependent

chr9_-_49798729 12.726 ENSMUST00000166811.2
Ncam1
neural cell adhesion molecule 1
chr9_-_16378231 12.675 ENSMUST00000082170.5
Fat3
FAT tumor suppressor homolog 3 (Drosophila)
chr13_+_16011851 12.582 ENSMUST00000042603.6
Inhba
inhibin beta-A
chr2_-_6722187 12.570 ENSMUST00000182657.1
Celf2
CUGBP, Elav-like family member 2
chr1_-_24612700 12.422 ENSMUST00000088336.1
Gm10222
predicted gene 10222
chr6_-_13838432 12.391 ENSMUST00000115492.1
Gpr85
G protein-coupled receptor 85
chr2_-_65567505 12.326 ENSMUST00000100069.2
Scn3a
sodium channel, voltage-gated, type III, alpha
chr13_+_109926832 12.300 ENSMUST00000117420.1
Pde4d
phosphodiesterase 4D, cAMP specific
chr1_+_66386968 12.235 ENSMUST00000145419.1
Map2
microtubule-associated protein 2
chr6_+_137410721 12.209 ENSMUST00000167002.1
Ptpro
protein tyrosine phosphatase, receptor type, O
chr2_-_6721890 12.193 ENSMUST00000114927.2
Celf2
CUGBP, Elav-like family member 2
chr4_+_13743424 12.189 ENSMUST00000006761.3
Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chrX_-_143933089 12.117 ENSMUST00000087313.3
Dcx
doublecortin
chr10_+_90576777 12.039 ENSMUST00000183136.1
ENSMUST00000182595.1
Anks1b

ankyrin repeat and sterile alpha motif domain containing 1B

chr10_+_69787431 11.981 ENSMUST00000183240.1
Ank3
ankyrin 3, epithelial
chr4_+_101507855 11.967 ENSMUST00000038207.5
Dnajc6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr14_-_36919314 11.895 ENSMUST00000182797.1
Ccser2
coiled-coil serine rich 2
chr5_+_81021202 11.880 ENSMUST00000117253.1
ENSMUST00000120128.1
Lphn3

latrophilin 3

chr1_+_153665666 11.866 ENSMUST00000111814.1
ENSMUST00000111810.1
Rgs8

regulator of G-protein signaling 8

chr2_-_80129458 11.831 ENSMUST00000102653.1
Pde1a
phosphodiesterase 1A, calmodulin-dependent
chr5_+_66968559 11.818 ENSMUST00000127184.1
Limch1
LIM and calponin homology domains 1
chr5_-_23616528 11.805 ENSMUST00000088392.4
Srpk2
serine/arginine-rich protein specific kinase 2
chr9_-_112232449 11.752 ENSMUST00000035085.5
Arpp21
cyclic AMP-regulated phosphoprotein, 21
chr3_-_126998408 11.747 ENSMUST00000182764.1
ENSMUST00000044443.8
Ank2

ankyrin 2, brain

chr6_-_99096196 11.682 ENSMUST00000175886.1
Foxp1
forkhead box P1
chrX_-_162565514 11.538 ENSMUST00000154424.1
Reps2
RALBP1 associated Eps domain containing protein 2
chr11_-_42000284 11.479 ENSMUST00000109292.2
ENSMUST00000109290.1
Gabrg2

gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2

chr11_-_42000532 11.437 ENSMUST00000070735.3
Gabrg2
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2
chr4_+_102254739 11.395 ENSMUST00000106907.2
Pde4b
phosphodiesterase 4B, cAMP specific
chrM_+_9870 11.372 ENSMUST00000084013.1
mt-Nd4l
mitochondrially encoded NADH dehydrogenase 4L
chr3_+_68572245 11.360 ENSMUST00000170788.2
Schip1
schwannomin interacting protein 1
chr2_-_6884975 11.267 ENSMUST00000114924.3
ENSMUST00000170438.1
ENSMUST00000114934.4
Celf2


CUGBP, Elav-like family member 2


chr8_-_67974567 11.264 ENSMUST00000098696.3
ENSMUST00000038959.9
ENSMUST00000093469.4
Psd3


pleckstrin and Sec7 domain containing 3


chr17_+_70522083 11.255 ENSMUST00000148486.1
ENSMUST00000133717.1
Dlgap1

discs, large (Drosophila) homolog-associated protein 1

chr10_+_90576708 11.213 ENSMUST00000182430.1
ENSMUST00000182960.1
ENSMUST00000182045.1
ENSMUST00000182083.1
Anks1b



ankyrin repeat and sterile alpha motif domain containing 1B



chr2_-_45117349 11.211 ENSMUST00000176438.2
Zeb2
zinc finger E-box binding homeobox 2
chr5_+_81021583 11.118 ENSMUST00000121707.1
Lphn3
latrophilin 3
chr15_-_37458523 11.032 ENSMUST00000116445.2
Ncald
neurocalcin delta
chr6_-_126166726 10.990 ENSMUST00000112244.2
ENSMUST00000050484.7
Ntf3

neurotrophin 3

chr1_+_153665274 10.969 ENSMUST00000152114.1
ENSMUST00000111812.1
Rgs8

regulator of G-protein signaling 8

chr9_+_47530173 10.944 ENSMUST00000114548.1
ENSMUST00000152459.1
ENSMUST00000143026.1
ENSMUST00000085909.2
ENSMUST00000114547.1
ENSMUST00000034581.3
Cadm1





cell adhesion molecule 1





chr6_-_138426735 10.911 ENSMUST00000162932.1
Lmo3
LIM domain only 3
chr13_-_101692624 10.902 ENSMUST00000035532.6
Pik3r1
phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)
chr1_+_81077204 10.862 ENSMUST00000123720.1
Nyap2
neuronal tyrosine-phophorylated phosphoinositide 3-kinase adaptor 2
chrX_-_143933204 10.852 ENSMUST00000112851.1
ENSMUST00000112856.2
ENSMUST00000033642.3
Dcx


doublecortin


chr1_-_37496095 10.832 ENSMUST00000148047.1
ENSMUST00000143636.1
Mgat4a

mannoside acetylglucosaminyltransferase 4, isoenzyme A

chr5_+_107497718 10.711 ENSMUST00000112671.2
A830010M20Rik
RIKEN cDNA A830010M20 gene
chr1_-_30863256 10.707 ENSMUST00000088310.3
Phf3
PHD finger protein 3
chr16_+_19028232 10.668 ENSMUST00000074116.4
Gm10088
predicted gene 10088
chr18_+_36952621 10.637 ENSMUST00000115661.2
Pcdha2
protocadherin alpha 2
chr5_+_66968416 10.486 ENSMUST00000038188.7
Limch1
LIM and calponin homology domains 1
chr15_-_56694525 10.481 ENSMUST00000050544.7
Has2
hyaluronan synthase 2
chr8_-_54724474 10.353 ENSMUST00000175915.1
Wdr17
WD repeat domain 17
chr6_-_138421379 10.344 ENSMUST00000163065.1
Lmo3
LIM domain only 3
chr19_+_26748268 10.262 ENSMUST00000175791.1
ENSMUST00000176698.1
ENSMUST00000177252.1
ENSMUST00000176475.1
ENSMUST00000112637.2
Smarca2




SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2




chr8_-_58911627 10.246 ENSMUST00000077447.4
Galntl6
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 6
chr4_-_76344227 10.153 ENSMUST00000050757.9
Ptprd
protein tyrosine phosphatase, receptor type, D
chr1_-_52190901 10.092 ENSMUST00000156887.1
ENSMUST00000129107.1
Gls

glutaminase

chr8_-_54718664 10.088 ENSMUST00000144711.2
ENSMUST00000093510.2
Wdr17

WD repeat domain 17

chr3_-_17786834 10.078 ENSMUST00000099198.2
Gm10742
predicted gene 10742
chr2_-_65567465 10.072 ENSMUST00000066432.5
Scn3a
sodium channel, voltage-gated, type III, alpha
chr6_-_55681257 9.983 ENSMUST00000044767.8
Neurod6
neurogenic differentiation 6
chr15_-_37459327 9.981 ENSMUST00000119730.1
ENSMUST00000120746.1
Ncald

neurocalcin delta

chr15_-_93519499 9.981 ENSMUST00000109255.2
Prickle1
prickle homolog 1 (Drosophila)
chr5_-_44799643 9.933 ENSMUST00000070748.5
Ldb2
LIM domain binding 2
chr2_+_61804453 9.765 ENSMUST00000048934.8
Tbr1
T-box brain gene 1
chr4_+_42922253 9.717 ENSMUST00000139100.1
N28178
expressed sequence N28178
chr2_-_45110241 9.700 ENSMUST00000177302.1
Zeb2
zinc finger E-box binding homeobox 2
chr6_-_99266494 9.638 ENSMUST00000113326.2
Foxp1
forkhead box P1
chr4_+_74013442 9.584 ENSMUST00000098006.2
ENSMUST00000084474.5
Frmd3

FERM domain containing 3

chr3_+_125404292 9.578 ENSMUST00000144344.1
Ndst4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr9_-_75597643 9.524 ENSMUST00000164100.1
Tmod2
tropomodulin 2
chr5_-_84417359 9.523 ENSMUST00000113401.1
Epha5
Eph receptor A5
chr1_-_155417394 9.518 ENSMUST00000111775.1
ENSMUST00000111774.1
Xpr1

xenotropic and polytropic retrovirus receptor 1

chr3_+_28263205 9.496 ENSMUST00000159236.2
Tnik
TRAF2 and NCK interacting kinase
chr17_+_70522149 9.487 ENSMUST00000140728.1
Dlgap1
discs, large (Drosophila) homolog-associated protein 1
chr18_-_35215008 9.479 ENSMUST00000091636.3
Lrrtm2
leucine rich repeat transmembrane neuronal 2
chr11_-_42182924 9.464 ENSMUST00000020707.5
ENSMUST00000132971.1
Gabra1

gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
28.3 84.9 GO:0007521 muscle cell fate determination(GO:0007521) cellular response to parathyroid hormone stimulus(GO:0071374) positive regulation of macrophage apoptotic process(GO:2000111)
12.3 73.9 GO:1903056 positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
12.3 49.3 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
9.5 76.2 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
8.7 78.4 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
8.6 25.8 GO:0001928 regulation of exocyst assembly(GO:0001928)
8.1 24.3 GO:0098923 retrograde trans-synaptic signaling by soluble gas(GO:0098923)
7.8 54.8 GO:0019532 oxalate transport(GO:0019532)
7.8 23.4 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892)
7.7 30.8 GO:0090126 protein complex assembly involved in synapse maturation(GO:0090126)
7.7 100.0 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
7.3 36.7 GO:0042636 negative regulation of hair cycle(GO:0042636) negative regulation of hair follicle development(GO:0051799) positive regulation of ovulation(GO:0060279)
7.3 22.0 GO:0003345 proepicardium cell migration involved in pericardium morphogenesis(GO:0003345)
7.1 85.2 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
6.6 59.4 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
5.9 52.8 GO:0071420 cellular response to histamine(GO:0071420)
5.7 39.9 GO:0005513 detection of calcium ion(GO:0005513)
5.7 22.8 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
5.7 28.4 GO:0046684 response to pyrethroid(GO:0046684)
5.5 16.6 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
5.4 32.2 GO:0072318 clathrin coat disassembly(GO:0072318)
5.2 15.7 GO:0007525 somatic muscle development(GO:0007525)
5.2 15.7 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
5.2 20.8 GO:0048686 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
5.2 15.5 GO:0017085 response to insecticide(GO:0017085)
5.0 55.2 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
5.0 14.9 GO:1903538 meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
4.9 14.7 GO:0002182 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
4.6 32.4 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
4.3 12.8 GO:0006597 spermine biosynthetic process(GO:0006597)
4.0 166.4 GO:0006376 mRNA splice site selection(GO:0006376)
3.8 11.5 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
3.8 56.9 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
3.7 18.6 GO:0007256 activation of JNKK activity(GO:0007256)
3.7 14.9 GO:0099552 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
3.6 10.9 GO:0009826 unidimensional cell growth(GO:0009826) susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
3.6 14.5 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
3.5 35.3 GO:0061470 interleukin-21 production(GO:0032625) T follicular helper cell differentiation(GO:0061470) interleukin-21 secretion(GO:0072619)
3.5 10.5 GO:0010838 positive regulation of keratinocyte proliferation(GO:0010838)
3.5 38.4 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
3.4 17.0 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
3.4 47.4 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
3.4 13.4 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
3.3 50.1 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
3.2 12.8 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
3.1 9.4 GO:0043379 memory T cell differentiation(GO:0043379)
3.1 40.9 GO:0070842 aggresome assembly(GO:0070842)
3.1 15.6 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)
3.1 24.7 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
3.1 12.2 GO:0003105 negative regulation of glomerular filtration(GO:0003105)
3.0 12.2 GO:2000481 positive regulation of cAMP-dependent protein kinase activity(GO:2000481)
3.0 11.9 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
2.9 8.7 GO:0050915 sensory perception of sour taste(GO:0050915)
2.9 2.9 GO:0043696 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
2.9 2.9 GO:0097324 melanocyte migration(GO:0097324)
2.9 14.3 GO:0006543 glutamine catabolic process(GO:0006543)
2.8 2.8 GO:0007113 endomitotic cell cycle(GO:0007113)
2.8 13.9 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
2.7 13.6 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
2.7 8.2 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)
2.7 18.9 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
2.6 2.6 GO:0072204 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
2.6 7.9 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
2.6 7.8 GO:0001543 ovarian follicle rupture(GO:0001543)
2.6 127.6 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
2.6 5.2 GO:2000790 regulation of mesenchymal cell proliferation involved in lung development(GO:2000790) negative regulation of mesenchymal cell proliferation involved in lung development(GO:2000791)
2.6 12.9 GO:0035063 nuclear speck organization(GO:0035063)
2.5 10.2 GO:0038128 ERBB2 signaling pathway(GO:0038128)
2.5 15.1 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
2.3 32.8 GO:0045161 neuronal ion channel clustering(GO:0045161)
2.3 14.0 GO:0086018 SA node cell action potential(GO:0086015) SA node cell to atrial cardiac muscle cell signalling(GO:0086018) SA node cell to atrial cardiac muscle cell communication(GO:0086070)
2.3 13.9 GO:1903847 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
2.3 11.5 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026) positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
2.2 20.1 GO:0010587 miRNA catabolic process(GO:0010587)
2.2 13.4 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
2.2 17.8 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
2.2 6.6 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
2.2 8.7 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
2.2 28.1 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
2.2 49.5 GO:0008090 retrograde axonal transport(GO:0008090)
2.1 6.3 GO:1904978 regulation of endosome organization(GO:1904978) positive regulation of endosome organization(GO:1904980)
2.1 6.2 GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912)
2.0 81.7 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
2.0 35.2 GO:0046069 cGMP catabolic process(GO:0046069)
1.9 13.6 GO:0014819 regulation of skeletal muscle contraction(GO:0014819)
1.9 13.2 GO:0046549 retinal cone cell development(GO:0046549)
1.9 5.6 GO:1903896 positive regulation of IRE1-mediated unfolded protein response(GO:1903896)
1.9 7.5 GO:1901475 pyruvate transmembrane transport(GO:1901475)
1.8 7.2 GO:0033194 response to hydroperoxide(GO:0033194)
1.7 7.0 GO:0006848 pyruvate transport(GO:0006848)
1.7 11.9 GO:1904017 response to Thyroglobulin triiodothyronine(GO:1904016) cellular response to Thyroglobulin triiodothyronine(GO:1904017)
1.7 10.1 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
1.7 8.3 GO:0048245 eosinophil chemotaxis(GO:0048245)
1.6 11.4 GO:1902856 negative regulation of nonmotile primary cilium assembly(GO:1902856)
1.6 3.3 GO:0003289 septum primum development(GO:0003284) atrial septum primum morphogenesis(GO:0003289)
1.6 14.5 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
1.6 9.5 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
1.6 7.9 GO:0033762 response to glucagon(GO:0033762)
1.6 3.2 GO:0043490 malate-aspartate shuttle(GO:0043490)
1.6 6.3 GO:0099550 trans-synaptic signalling, modulating synaptic transmission(GO:0099550)
1.6 1.6 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
1.6 26.6 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
1.5 6.2 GO:0097494 positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944) regulation of vesicle size(GO:0097494)
1.5 7.6 GO:0015692 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
1.5 4.5 GO:0035864 response to potassium ion(GO:0035864) cellular response to potassium ion(GO:0035865)
1.5 16.3 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
1.5 8.8 GO:0051694 pointed-end actin filament capping(GO:0051694)
1.5 5.8 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005)
1.4 5.7 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
1.4 4.2 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
1.4 4.1 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
1.4 4.1 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
1.4 10.8 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
1.3 9.4 GO:0060267 positive regulation of respiratory burst(GO:0060267)
1.3 10.7 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
1.3 18.8 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
1.3 68.1 GO:0034605 cellular response to heat(GO:0034605)
1.3 3.9 GO:0019805 quinolinate biosynthetic process(GO:0019805)
1.3 11.6 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
1.3 31.0 GO:0002091 negative regulation of receptor internalization(GO:0002091)
1.2 3.7 GO:0007262 STAT protein import into nucleus(GO:0007262)
1.2 74.9 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
1.2 7.3 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
1.2 15.9 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
1.2 29.3 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
1.2 4.7 GO:2000821 regulation of grooming behavior(GO:2000821)
1.2 11.7 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
1.2 4.6 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
1.2 6.9 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
1.2 3.5 GO:0060060 post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
1.1 18.2 GO:0051447 negative regulation of meiotic cell cycle(GO:0051447)
1.1 6.8 GO:0098964 dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964)
1.1 7.8 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
1.1 5.5 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
1.1 10.9 GO:1900103 positive regulation of endoplasmic reticulum unfolded protein response(GO:1900103)
1.1 6.5 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
1.1 4.3 GO:0060178 regulation of exocyst localization(GO:0060178)
1.0 2.1 GO:0099527 postsynapse to nucleus signaling pathway(GO:0099527)
1.0 5.1 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
1.0 12.3 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
1.0 4.1 GO:0021502 neural fold elevation formation(GO:0021502)
1.0 7.0 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
1.0 8.0 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
1.0 2.0 GO:0070343 white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350)
1.0 18.3 GO:2001224 positive regulation of neuron migration(GO:2001224)
1.0 1.9 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.9 2.8 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.9 4.5 GO:0016198 axon choice point recognition(GO:0016198)
0.9 0.9 GO:0060527 prostate glandular acinus morphogenesis(GO:0060526) prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis(GO:0060527)
0.9 14.3 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.9 23.8 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.8 2.5 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
0.8 2.5 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.8 2.5 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.8 4.1 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.8 3.3 GO:0090261 positive regulation of inclusion body assembly(GO:0090261)
0.8 21.0 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.8 24.8 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.8 7.1 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.8 42.7 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.8 4.6 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.8 1.5 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
0.7 4.4 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.7 9.5 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.7 3.6 GO:1900095 regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.7 4.9 GO:0018344 protein geranylgeranylation(GO:0018344)
0.7 2.1 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.7 15.9 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.7 1.4 GO:0051794 regulation of catagen(GO:0051794) positive regulation of catagen(GO:0051795)
0.7 2.0 GO:0045409 negative regulation of interleukin-6 biosynthetic process(GO:0045409)
0.7 2.7 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.7 4.6 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.7 2.0 GO:2000393 negative regulation of lamellipodium organization(GO:1902744) negative regulation of lamellipodium morphogenesis(GO:2000393)
0.6 1.9 GO:0071649 negative regulation of acute inflammatory response to antigenic stimulus(GO:0002865) regulation of chemokine (C-C motif) ligand 5 production(GO:0071649)
0.6 3.8 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.6 2.6 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.6 2.6 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.6 10.9 GO:0001553 luteinization(GO:0001553)
0.6 4.5 GO:0030035 microspike assembly(GO:0030035)
0.6 5.0 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
0.6 13.0 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.6 14.7 GO:0030325 adrenal gland development(GO:0030325)
0.6 4.3 GO:2000232 regulation of rRNA processing(GO:2000232)
0.6 3.0 GO:0006041 glucosamine metabolic process(GO:0006041)
0.6 2.4 GO:2000194 regulation of female gonad development(GO:2000194)
0.6 2.4 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.6 17.4 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.6 4.2 GO:0014807 regulation of somitogenesis(GO:0014807)
0.6 4.1 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.6 13.4 GO:0008340 determination of adult lifespan(GO:0008340)
0.6 4.1 GO:0030242 pexophagy(GO:0030242)
0.6 2.3 GO:0019323 pentose catabolic process(GO:0019323)
0.6 20.2 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.6 3.5 GO:0034773 histone H4-K20 trimethylation(GO:0034773) establishment of Sertoli cell barrier(GO:0097368)
0.6 3.5 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.6 3.4 GO:0035095 behavioral response to nicotine(GO:0035095)
0.6 4.0 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.6 1.7 GO:1900623 regulation of mast cell cytokine production(GO:0032763) monocyte aggregation(GO:0070487) regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.6 6.2 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.6 1.7 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.6 38.0 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.5 4.3 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055) ribosomal small subunit export from nucleus(GO:0000056)
0.5 9.2 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.5 5.9 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.5 4.8 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.5 21.6 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.5 23.2 GO:0001919 regulation of receptor recycling(GO:0001919)
0.5 1.6 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.5 4.7 GO:0010793 regulation of mRNA export from nucleus(GO:0010793) regulation of ribonucleoprotein complex localization(GO:2000197)
0.5 4.1 GO:0010818 T cell chemotaxis(GO:0010818)
0.5 2.6 GO:0033234 regulation of protein sumoylation(GO:0033233) negative regulation of protein sumoylation(GO:0033234)
0.5 3.0 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.5 4.0 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.5 2.5 GO:0007258 JUN phosphorylation(GO:0007258)
0.5 4.0 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.5 4.4 GO:0061635 regulation of protein complex stability(GO:0061635)
0.5 6.2 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.5 1.9 GO:0097167 circadian regulation of translation(GO:0097167)
0.5 4.8 GO:1904754 positive regulation of vascular associated smooth muscle cell migration(GO:1904754)
0.5 1.9 GO:0030576 Cajal body organization(GO:0030576)
0.5 2.3 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.5 5.5 GO:0006895 Golgi to endosome transport(GO:0006895)
0.5 1.4 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.4 4.0 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.4 4.5 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.4 1.3 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) positive regulation of neuromuscular junction development(GO:1904398)
0.4 23.7 GO:0010977 negative regulation of neuron projection development(GO:0010977)
0.4 1.7 GO:0046368 GDP-L-fucose metabolic process(GO:0046368)
0.4 2.1 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.4 0.4 GO:1902177 positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902177)
0.4 0.8 GO:0048636 positive regulation of striated muscle tissue development(GO:0045844) positive regulation of muscle organ development(GO:0048636) positive regulation of muscle tissue development(GO:1901863)
0.4 2.5 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.4 31.1 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.4 13.3 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.4 2.5 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.4 2.9 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.4 0.8 GO:0086053 AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
0.4 2.4 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.4 0.8 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.4 1.2 GO:0098886 modification of dendritic spine(GO:0098886)
0.4 12.9 GO:0007416 synapse assembly(GO:0007416)
0.4 1.2 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.4 5.0 GO:0045793 positive regulation of cell size(GO:0045793)
0.4 0.4 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.4 3.4 GO:0006449 regulation of translational termination(GO:0006449)
0.4 3.8 GO:0051604 protein maturation(GO:0051604)
0.4 2.2 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.4 1.1 GO:0089700 protein kinase D signaling(GO:0089700)
0.4 1.4 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.4 2.5 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.3 2.4 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.3 2.4 GO:0045017 glycerolipid biosynthetic process(GO:0045017)
0.3 5.2 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.3 4.8 GO:1900746 regulation of vascular endothelial growth factor signaling pathway(GO:1900746)
0.3 2.3 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.3 4.4 GO:0060979 vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.3 1.0 GO:0002329 pre-B cell differentiation(GO:0002329)
0.3 3.3 GO:0051302 regulation of cell division(GO:0051302)
0.3 6.9 GO:0007019 microtubule depolymerization(GO:0007019)
0.3 3.0 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.3 2.0 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
0.3 1.3 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.3 1.0 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.3 2.3 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.3 3.6 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.3 0.6 GO:1905077 negative regulation of interleukin-17 secretion(GO:1905077)
0.3 1.6 GO:0045955 negative regulation of calcium ion-dependent exocytosis(GO:0045955) negative regulation of fertilization(GO:0060467)
0.3 1.6 GO:0090005 negative regulation of Golgi to plasma membrane protein transport(GO:0042997) negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.3 3.1 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.3 3.4 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.3 1.5 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.3 12.4 GO:0045773 positive regulation of axon extension(GO:0045773)
0.3 11.3 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.3 2.4 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.3 14.7 GO:0030032 lamellipodium assembly(GO:0030032)
0.3 5.6 GO:0045116 protein neddylation(GO:0045116)
0.3 2.6 GO:0006020 inositol metabolic process(GO:0006020)
0.3 5.9 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.3 14.2 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.3 4.7 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.3 7.5 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.3 2.2 GO:0072600 establishment of protein localization to Golgi(GO:0072600)
0.3 1.3 GO:0042795 snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.3 2.7 GO:0006968 cellular defense response(GO:0006968)
0.3 0.5 GO:0001951 intestinal D-glucose absorption(GO:0001951) regulation of microvillus length(GO:0032532) terminal web assembly(GO:1902896)
0.3 0.8 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.3 0.8 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.3 4.0 GO:0060074 synapse maturation(GO:0060074)
0.3 4.7 GO:1901381 positive regulation of potassium ion transmembrane transport(GO:1901381)
0.3 5.1 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.3 1.0 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.3 3.5 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.3 1.3 GO:0046543 development of secondary sexual characteristics(GO:0045136) development of secondary female sexual characteristics(GO:0046543)
0.3 2.0 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.3 0.8 GO:0071415 cellular response to caffeine(GO:0071313) cellular response to purine-containing compound(GO:0071415)
0.2 3.2 GO:0021860 pyramidal neuron development(GO:0021860)
0.2 5.7 GO:0016180 snRNA processing(GO:0016180)
0.2 5.0 GO:0003351 epithelial cilium movement(GO:0003351)
0.2 2.2 GO:0003084 positive regulation of systemic arterial blood pressure(GO:0003084)
0.2 1.2 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.2 3.3 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.2 4.3 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.2 4.2 GO:0006622 protein targeting to lysosome(GO:0006622)
0.2 1.6 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.2 2.3 GO:0015701 bicarbonate transport(GO:0015701)
0.2 3.0 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.2 9.6 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.2 1.7 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.2 1.7 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.2 1.1 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.2 0.6 GO:0051030 snRNA transport(GO:0051030)
0.2 1.5 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.2 3.1 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.2 23.9 GO:0007266 Rho protein signal transduction(GO:0007266)
0.2 31.2 GO:0016358 dendrite development(GO:0016358)
0.2 0.2 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.2 1.6 GO:0035608 protein deglutamylation(GO:0035608)
0.2 12.7 GO:0019722 calcium-mediated signaling(GO:0019722)
0.2 2.4 GO:0000281 mitotic cytokinesis(GO:0000281)
0.2 5.2 GO:0014037 Schwann cell differentiation(GO:0014037)
0.2 0.8 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.2 0.8 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.2 4.7 GO:0030851 granulocyte differentiation(GO:0030851)
0.2 1.9 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.2 1.3 GO:2000507 negative regulation of peptidyl-threonine phosphorylation(GO:0010801) positive regulation of energy homeostasis(GO:2000507)
0.2 3.8 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.2 8.5 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.2 3.0 GO:0006491 N-glycan processing(GO:0006491)
0.2 1.1 GO:0001895 retina homeostasis(GO:0001895)
0.2 4.8 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.2 2.2 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.2 3.3 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.2 1.8 GO:0048670 regulation of collateral sprouting(GO:0048670)
0.2 1.1 GO:0097120 receptor localization to synapse(GO:0097120)
0.2 4.9 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.2 6.0 GO:0046324 regulation of glucose import(GO:0046324)
0.2 1.0 GO:0034587 piRNA metabolic process(GO:0034587)
0.2 0.7 GO:0043931 ossification involved in bone maturation(GO:0043931)
0.2 0.7 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.2 0.8 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.2 0.8 GO:0051684 maintenance of Golgi location(GO:0051684)
0.2 1.0 GO:0071494 cellular response to UV-C(GO:0071494)
0.2 2.0 GO:0006110 regulation of glycolytic process(GO:0006110)
0.2 2.7 GO:0060009 Sertoli cell development(GO:0060009)
0.2 3.0 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.2 1.3 GO:0046085 adenosine metabolic process(GO:0046085)
0.2 0.3 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.2 1.6 GO:0034453 microtubule anchoring(GO:0034453)
0.2 0.6 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.2 0.5 GO:0010873 positive regulation of cholesterol esterification(GO:0010873)
0.2 1.5 GO:0014002 astrocyte development(GO:0014002)
0.2 2.6 GO:0002063 chondrocyte development(GO:0002063)
0.1 1.6 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.1 7.5 GO:0050770 regulation of axonogenesis(GO:0050770)
0.1 0.4 GO:1904181 positive regulation of membrane depolarization(GO:1904181)
0.1 0.7 GO:0097090 presynaptic membrane organization(GO:0097090)
0.1 0.6 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.1 1.3 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 1.1 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.1 1.8 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 2.4 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.1 0.4 GO:0048149 behavioral response to ethanol(GO:0048149)
0.1 4.7 GO:0042073 intraciliary transport(GO:0042073)
0.1 1.9 GO:0030865 cortical cytoskeleton organization(GO:0030865)
0.1 8.9 GO:0014065 phosphatidylinositol 3-kinase signaling(GO:0014065)
0.1 3.8 GO:0008361 regulation of cell size(GO:0008361)
0.1 0.6 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788)
0.1 7.9 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.1 0.6 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.1 3.4 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.1 1.5 GO:0000729 DNA double-strand break processing(GO:0000729)
0.1 1.3 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.1 1.8 GO:0042254 ribosome biogenesis(GO:0042254)
0.1 4.2 GO:0032091 negative regulation of protein binding(GO:0032091)
0.1 0.5 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.1 1.9 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.1 1.5 GO:0043248 proteasome assembly(GO:0043248)
0.1 27.9 GO:0007186 G-protein coupled receptor signaling pathway(GO:0007186)
0.1 1.2 GO:1903077 negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.1 3.8 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.1 1.8 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.1 3.2 GO:0097576 autophagosome maturation(GO:0097352) vacuole fusion(GO:0097576)
0.1 2.0 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.1 2.0 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.1 0.4 GO:0035826 rubidium ion transport(GO:0035826) cellular hypotonic response(GO:0071476)
0.1 0.4 GO:0045075 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.1 4.0 GO:0006270 DNA replication initiation(GO:0006270)
0.1 2.8 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.1 4.5 GO:0030071 regulation of mitotic metaphase/anaphase transition(GO:0030071) regulation of metaphase/anaphase transition of cell cycle(GO:1902099)
0.1 5.1 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.1 0.7 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.1 0.2 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.1 0.9 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.1 3.9 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.1 2.8 GO:0050688 regulation of defense response to virus(GO:0050688)
0.1 0.6 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.1 4.7 GO:0050806 positive regulation of synaptic transmission(GO:0050806)
0.1 0.7 GO:0043173 nucleotide salvage(GO:0043173)
0.1 6.0 GO:0071805 potassium ion transmembrane transport(GO:0071805)
0.1 4.9 GO:0001578 microtubule bundle formation(GO:0001578)
0.1 3.1 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.1 0.2 GO:0046689 response to mercury ion(GO:0046689)
0.1 1.4 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.1 0.2 GO:0061743 motor learning(GO:0061743)
0.1 3.6 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.1 0.9 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.1 0.2 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.1 0.8 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.1 0.2 GO:0015677 copper ion import(GO:0015677)
0.1 0.7 GO:0097186 amelogenesis(GO:0097186)
0.1 2.1 GO:0030048 actin filament-based movement(GO:0030048)
0.1 2.1 GO:2000378 negative regulation of reactive oxygen species metabolic process(GO:2000378)
0.1 3.9 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.1 1.0 GO:0005980 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.1 1.2 GO:0045806 negative regulation of endocytosis(GO:0045806)
0.0 0.8 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.3 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.3 GO:0035459 cargo loading into vesicle(GO:0035459) cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.2 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.5 GO:0035308 negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.0 3.2 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 0.5 GO:0035019 somatic stem cell population maintenance(GO:0035019)
0.0 0.8 GO:0035036 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036)
0.0 2.9 GO:0051028 mRNA transport(GO:0051028)
0.0 1.9 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 0.1 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.0 1.4 GO:0007030 Golgi organization(GO:0007030)
0.0 4.2 GO:0018209 peptidyl-serine modification(GO:0018209)
0.0 1.9 GO:0000086 G2/M transition of mitotic cell cycle(GO:0000086)
0.0 0.1 GO:0046462 monoacylglycerol metabolic process(GO:0046462)
0.0 0.1 GO:0042177 negative regulation of protein catabolic process(GO:0042177)
0.0 0.1 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.1 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0 0.1 GO:0061365 positive regulation of triglyceride lipase activity(GO:0061365)
0.0 0.8 GO:0006342 chromatin silencing(GO:0006342)
0.0 0.1 GO:0045930 negative regulation of mitotic cell cycle(GO:0045930)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
12.2 36.7 GO:0043512 inhibin A complex(GO:0043512)
10.4 41.6 GO:0031673 H zone(GO:0031673)
7.0 21.0 GO:0072534 perineuronal net(GO:0072534)
6.9 34.5 GO:0032437 cuticular plate(GO:0032437)
6.3 57.1 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
4.9 43.7 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
4.6 69.2 GO:0043083 synaptic cleft(GO:0043083)
4.1 78.4 GO:0071564 npBAF complex(GO:0071564)
3.8 64.4 GO:0031045 dense core granule(GO:0031045)
3.5 52.8 GO:1902711 GABA-A receptor complex(GO:1902711)
3.0 60.9 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
3.0 78.4 GO:0000930 gamma-tubulin complex(GO:0000930)
3.0 14.9 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
2.9 11.5 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
2.8 42.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
2.5 52.0 GO:0031430 M band(GO:0031430)
2.4 11.9 GO:0098831 presynaptic active zone cytoplasmic component(GO:0098831)
2.0 32.2 GO:0043196 varicosity(GO:0043196)
2.0 25.9 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
2.0 41.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
1.7 467.7 GO:0045211 postsynaptic membrane(GO:0045211)
1.6 6.3 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
1.6 7.9 GO:0000235 astral microtubule(GO:0000235)
1.5 7.6 GO:0070826 paraferritin complex(GO:0070826)
1.4 4.2 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
1.4 16.5 GO:0044300 cerebellar mossy fiber(GO:0044300)
1.4 17.6 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
1.3 39.9 GO:0032809 neuronal cell body membrane(GO:0032809)
1.2 45.0 GO:0097458 neuron part(GO:0097458)
1.1 11.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
1.1 36.1 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
1.1 3.4 GO:0099573 glutamatergic postsynaptic density(GO:0099573)
1.1 5.5 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
1.1 4.3 GO:0001651 dense fibrillar component(GO:0001651)
1.1 11.7 GO:0030122 AP-2 adaptor complex(GO:0030122)
1.0 14.5 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
1.0 13.3 GO:0097542 ciliary tip(GO:0097542)
1.0 42.2 GO:0044295 axonal growth cone(GO:0044295)
1.0 4.9 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
1.0 22.4 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
1.0 8.6 GO:0044294 dendritic growth cone(GO:0044294)
0.9 3.7 GO:0033269 internode region of axon(GO:0033269)
0.9 3.4 GO:0008623 CHRAC(GO:0008623)
0.9 4.3 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.8 9.5 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.8 7.9 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.8 7.9 GO:0071439 clathrin complex(GO:0071439)
0.8 15.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.8 10.8 GO:0042788 polysomal ribosome(GO:0042788)
0.8 3.0 GO:0000791 euchromatin(GO:0000791)
0.7 8.7 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.7 7.9 GO:0045275 respiratory chain complex III(GO:0045275)
0.7 12.8 GO:0031226 intrinsic component of plasma membrane(GO:0031226)
0.7 2.7 GO:0031983 vesicle lumen(GO:0031983)
0.7 30.3 GO:0044291 cell-cell contact zone(GO:0044291)
0.7 3.9 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.6 8.2 GO:0042581 specific granule(GO:0042581)
0.6 3.7 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.6 4.8 GO:0097165 nuclear stress granule(GO:0097165)
0.6 1.7 GO:0044305 calyx of Held(GO:0044305)
0.6 33.8 GO:0070469 respiratory chain(GO:0070469)
0.5 1.6 GO:0008091 spectrin(GO:0008091)
0.5 15.7 GO:0042734 presynaptic membrane(GO:0042734)
0.5 2.6 GO:0032585 multivesicular body membrane(GO:0032585)
0.5 1.5 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.5 104.0 GO:0060076 excitatory synapse(GO:0060076)
0.5 4.0 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.5 6.5 GO:1990635 proximal dendrite(GO:1990635)
0.5 8.4 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.5 4.9 GO:0070545 PeBoW complex(GO:0070545)
0.5 3.5 GO:0071437 invadopodium(GO:0071437)
0.5 14.7 GO:0009986 cell surface(GO:0009986)
0.5 1.9 GO:0005726 perichromatin fibrils(GO:0005726)
0.5 15.3 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.5 3.3 GO:0070695 FHF complex(GO:0070695)
0.5 1.4 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.5 2.4 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.5 22.5 GO:0016328 lateral plasma membrane(GO:0016328)
0.5 1.4 GO:0018444 translation release factor complex(GO:0018444)
0.5 1.8 GO:0097454 Schwann cell microvillus(GO:0097454)
0.4 8.4 GO:0097228 sperm principal piece(GO:0097228)
0.4 3.5 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.4 4.4 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.4 56.2 GO:0030017 sarcomere(GO:0030017)
0.4 3.8 GO:0030673 axolemma(GO:0030673)
0.4 6.8 GO:0032039 integrator complex(GO:0032039)
0.4 2.9 GO:0005677 chromatin silencing complex(GO:0005677)
0.4 6.3 GO:0042101 T cell receptor complex(GO:0042101)
0.4 2.9 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.4 2.0 GO:0072487 MSL complex(GO:0072487)
0.4 36.2 GO:0016605 PML body(GO:0016605)
0.4 3.6 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.4 4.3 GO:0005642 annulate lamellae(GO:0005642)
0.4 9.8 GO:0001917 photoreceptor inner segment(GO:0001917)
0.4 14.3 GO:0005719 nuclear euchromatin(GO:0005719)
0.4 1.5 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.4 4.1 GO:0030175 filopodium(GO:0030175)
0.4 1.1 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.4 1.8 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.4 37.7 GO:0016363 nuclear matrix(GO:0016363)
0.3 27.5 GO:0042641 actomyosin(GO:0042641)
0.3 4.5 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.3 2.4 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.3 269.9 GO:0005887 integral component of plasma membrane(GO:0005887)
0.3 4.9 GO:0030127 COPII vesicle coat(GO:0030127)
0.3 3.3 GO:0031595 nuclear proteasome complex(GO:0031595)
0.3 4.3 GO:0043198 dendritic shaft(GO:0043198)
0.3 0.3 GO:0051286 cell tip(GO:0051286)
0.3 28.2 GO:0031225 anchored component of membrane(GO:0031225)
0.3 6.1 GO:0030139 endocytic vesicle(GO:0030139)
0.3 12.5 GO:0008023 transcription elongation factor complex(GO:0008023)
0.3 23.1 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.2 12.5 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.2 27.3 GO:0036064 ciliary basal body(GO:0036064)
0.2 2.1 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.2 0.2 GO:0097487 amphisome(GO:0044753) multivesicular body, internal vesicle(GO:0097487)
0.2 2.6 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.2 1.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.2 1.1 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.2 17.3 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.2 0.5 GO:1990357 terminal web(GO:1990357)
0.2 1.0 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.2 1.5 GO:0071565 nBAF complex(GO:0071565)
0.2 4.2 GO:0017053 transcriptional repressor complex(GO:0017053)
0.2 1.6 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.2 0.6 GO:0070876 SOSS complex(GO:0070876)
0.2 15.1 GO:0000118 histone deacetylase complex(GO:0000118)
0.2 0.3 GO:0030478 actin cap(GO:0030478)
0.1 3.1 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 3.7 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1 9.0 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 5.6 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 0.7 GO:0033263 CORVET complex(GO:0033263)
0.1 0.8 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.1 1.7 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 3.2 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.1 1.3 GO:0097470 ribbon synapse(GO:0097470)
0.1 3.4 GO:0035861 site of double-strand break(GO:0035861)
0.1 2.4 GO:0012505 endomembrane system(GO:0012505)
0.1 6.5 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 1.7 GO:0001772 immunological synapse(GO:0001772)
0.1 3.8 GO:0005801 cis-Golgi network(GO:0005801)
0.1 3.6 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 1.5 GO:0005771 multivesicular body(GO:0005771)
0.1 2.7 GO:0035371 microtubule plus-end(GO:0035371)
0.1 10.0 GO:0005802 trans-Golgi network(GO:0005802)
0.1 8.3 GO:0055037 recycling endosome(GO:0055037)
0.1 1.7 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.1 21.9 GO:0000139 Golgi membrane(GO:0000139)
0.1 2.3 GO:0045335 phagocytic vesicle(GO:0045335)
0.1 1.2 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.1 11.9 GO:0005770 late endosome(GO:0005770)
0.1 1.0 GO:0097223 sperm flagellum(GO:0036126) sperm part(GO:0097223)
0.1 2.9 GO:0008180 COP9 signalosome(GO:0008180)
0.1 1.1 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 2.5 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 1.2 GO:0005923 bicellular tight junction(GO:0005923)
0.1 2.3 GO:0005902 microvillus(GO:0005902)
0.1 0.8 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 2.3 GO:0031306 intrinsic component of mitochondrial outer membrane(GO:0031306)
0.1 3.0 GO:0032587 ruffle membrane(GO:0032587)
0.1 1.6 GO:0034399 nuclear periphery(GO:0034399)
0.1 4.9 GO:0005643 nuclear pore(GO:0005643)
0.1 0.7 GO:0030131 clathrin adaptor complex(GO:0030131)
0.1 3.4 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 3.4 GO:0005657 replication fork(GO:0005657)
0.1 2.5 GO:0005871 kinesin complex(GO:0005871)
0.1 12.0 GO:0005635 nuclear envelope(GO:0005635)
0.1 27.6 GO:0015630 microtubule cytoskeleton(GO:0015630)
0.0 0.2 GO:0008537 proteasome activator complex(GO:0008537)
0.0 3.8 GO:0044455 mitochondrial membrane part(GO:0044455)
0.0 0.7 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.9 GO:0005682 U5 snRNP(GO:0005682)
0.0 4.5 GO:0045202 synapse(GO:0045202)
0.0 24.7 GO:0005730 nucleolus(GO:0005730)
0.0 0.2 GO:0009925 basal plasma membrane(GO:0009925)
0.0 2.1 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.8 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.2 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 2.1 GO:0005769 early endosome(GO:0005769)
0.0 0.5 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 20.2 GO:0005794 Golgi apparatus(GO:0005794)
0.0 0.9 GO:0072562 blood microparticle(GO:0072562)
0.0 0.4 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 3.5 GO:0005681 spliceosomal complex(GO:0005681)
0.0 0.5 GO:0043204 perikaryon(GO:0043204)
0.0 1.0 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.2 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.9 GO:0043235 receptor complex(GO:0043235)
0.0 8.5 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 0.3 GO:0043195 terminal bouton(GO:0043195)
0.0 0.0 GO:0043209 myelin sheath(GO:0043209)
0.0 0.1 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
13.5 54.2 GO:0030348 syntaxin-3 binding(GO:0030348)
8.7 69.4 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
8.5 50.8 GO:0070699 type II activin receptor binding(GO:0070699)
7.7 61.6 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529)
7.1 7.1 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
6.5 19.5 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
5.0 25.2 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
5.0 15.1 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
5.0 54.8 GO:0019531 secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531)
4.9 19.4 GO:0004952 dopamine neurotransmitter receptor activity(GO:0004952)
4.7 33.1 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
4.4 13.2 GO:0008502 melatonin receptor activity(GO:0008502)
4.2 29.3 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
4.2 16.7 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
4.1 107.3 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
4.1 78.4 GO:0035198 miRNA binding(GO:0035198)
3.9 19.7 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
3.9 15.7 GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038)
3.8 30.4 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
3.5 10.5 GO:0050501 hyaluronan synthase activity(GO:0050501)
3.3 32.8 GO:0042043 neurexin family protein binding(GO:0042043)
3.2 12.8 GO:0019808 polyamine binding(GO:0019808)
3.0 164.3 GO:0036002 pre-mRNA binding(GO:0036002)
2.9 14.3 GO:0004359 glutaminase activity(GO:0004359)
2.7 10.9 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
2.7 32.2 GO:0097109 neuroligin family protein binding(GO:0097109)
2.7 13.4 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
2.7 8.0 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
2.7 42.6 GO:0004890 GABA-A receptor activity(GO:0004890)
2.5 22.8 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
2.4 53.9 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
2.4 9.5 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
2.3 11.5 GO:0050816 phosphothreonine binding(GO:0050816)
2.3 9.1 GO:0098960 postsynaptic neurotransmitter receptor activity(GO:0098960) neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
2.2 6.6 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
2.2 11.0 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
2.1 6.3 GO:0005030 neurotrophin receptor activity(GO:0005030)
2.1 4.1 GO:0008046 axon guidance receptor activity(GO:0008046)
2.0 8.2 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
2.0 57.1 GO:1905030 voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
1.9 98.8 GO:0046875 ephrin receptor binding(GO:0046875)
1.9 31.0 GO:0004385 guanylate kinase activity(GO:0004385)
1.9 7.5 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
1.9 33.7 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
1.8 22.1 GO:0050897 cobalt ion binding(GO:0050897)
1.8 9.2 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
1.8 18.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
1.8 8.9 GO:0055100 adiponectin binding(GO:0055100)
1.8 15.9 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
1.7 100.6 GO:0030507 spectrin binding(GO:0030507)
1.7 20.8 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
1.7 5.0 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
1.6 33.3 GO:0030506 ankyrin binding(GO:0030506)
1.4 4.3 GO:0044547 DNA topoisomerase binding(GO:0044547)
1.4 11.4 GO:0002162 dystroglycan binding(GO:0002162)
1.4 4.2 GO:0004111 creatine kinase activity(GO:0004111)
1.4 40.8 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
1.4 4.1 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
1.3 40.4 GO:0008157 protein phosphatase 1 binding(GO:0008157)
1.3 6.5 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
1.3 45.9 GO:0070412 R-SMAD binding(GO:0070412)
1.3 6.3 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
1.2 4.8 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
1.2 21.0 GO:0005540 hyaluronic acid binding(GO:0005540)
1.1 3.4 GO:0016015 morphogen activity(GO:0016015)
1.1 36.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)
1.1 15.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
1.1 17.9 GO:0030275 LRR domain binding(GO:0030275)
1.0 3.0 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
1.0 7.1 GO:0035727 lysophosphatidic acid binding(GO:0035727)
1.0 30.2 GO:0043014 alpha-tubulin binding(GO:0043014)
1.0 7.9 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
1.0 4.0 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
1.0 15.8 GO:0046625 sphingolipid binding(GO:0046625)
1.0 8.8 GO:0005523 tropomyosin binding(GO:0005523)
1.0 34.4 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.9 3.8 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.9 18.1 GO:0043422 protein kinase B binding(GO:0043422)
0.9 4.4 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.9 27.8 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.8 5.9 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.8 2.5 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.8 4.1 GO:0070700 BMP receptor binding(GO:0070700)
0.8 2.4 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.8 2.4 GO:0071568 UFM1 transferase activity(GO:0071568)
0.8 3.2 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.8 3.2 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.7 2.9 GO:0015410 manganese-transporting ATPase activity(GO:0015410)
0.7 2.9 GO:0001847 opsonin receptor activity(GO:0001847)
0.7 4.3 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.7 3.5 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.7 21.0 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.7 6.1 GO:0048185 activin binding(GO:0048185)
0.7 2.7 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.7 5.3 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.7 1.3 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.6 3.2 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.6 2.5 GO:0050733 RS domain binding(GO:0050733)
0.6 1.9 GO:0070140 isopeptidase activity(GO:0070122) ubiquitin-like protein-specific isopeptidase activity(GO:0070138) SUMO-specific isopeptidase activity(GO:0070140)
0.6 4.2 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.6 24.4 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.6 3.0 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.6 17.2 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.6 13.0 GO:0031489 myosin V binding(GO:0031489)
0.6 4.0 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.6 58.7 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.6 5.6 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.6 14.5 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.6 3.3 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.6 1.7 GO:0001565 phorbol ester receptor activity(GO:0001565) non-kinase phorbol ester receptor activity(GO:0001566)
0.5 68.1 GO:0005516 calmodulin binding(GO:0005516)
0.5 56.9 GO:0005057 receptor signaling protein activity(GO:0005057)
0.5 4.2 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.5 26.0 GO:0005262 calcium channel activity(GO:0005262)
0.5 2.6 GO:0052833 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.5 10.2 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.5 89.4 GO:0004386 helicase activity(GO:0004386)
0.5 55.0 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.5 4.4 GO:0001972 retinoic acid binding(GO:0001972)
0.5 4.3 GO:0030274 LIM domain binding(GO:0030274)
0.5 3.3 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.5 6.9 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.5 7.3 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.5 5.0 GO:0017166 vinculin binding(GO:0017166)
0.5 14.2 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.5 1.4 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.5 1.8 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.4 1.3 GO:0043758 acetate-CoA ligase (ADP-forming) activity(GO:0043758)
0.4 4.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.4 5.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.4 3.3 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.4 12.1 GO:0017091 AU-rich element binding(GO:0017091)
0.4 0.8 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798)
0.4 3.6 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.4 2.0 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.4 2.8 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.4 2.3 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.4 2.3 GO:0004984 olfactory receptor activity(GO:0004984)
0.4 17.1 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.4 2.7 GO:0005112 Notch binding(GO:0005112)
0.4 1.9 GO:0034056 estrogen response element binding(GO:0034056)
0.4 7.3 GO:0042805 actinin binding(GO:0042805)
0.4 3.8 GO:0015197 peptide transporter activity(GO:0015197)
0.4 82.1 GO:0008017 microtubule binding(GO:0008017)
0.4 1.1 GO:0048019 receptor antagonist activity(GO:0048019)
0.3 9.0 GO:0071889 14-3-3 protein binding(GO:0071889)
0.3 1.0 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.3 3.4 GO:0031543 peptidyl-proline dioxygenase activity(GO:0031543)
0.3 3.4 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.3 5.1 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.3 10.8 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.3 3.0 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.3 6.0 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.3 2.6 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.3 3.3 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.3 2.6 GO:0003993 acid phosphatase activity(GO:0003993)
0.3 11.0 GO:0001786 phosphatidylserine binding(GO:0001786)
0.3 3.8 GO:0004000 adenosine deaminase activity(GO:0004000)
0.3 0.6 GO:0061665 SUMO ligase activity(GO:0061665)
0.3 0.6 GO:0070052 collagen V binding(GO:0070052)
0.3 0.9 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.3 9.4 GO:0048365 Rac GTPase binding(GO:0048365)
0.3 2.2 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.3 1.5 GO:0045499 chemorepellent activity(GO:0045499)
0.3 3.6 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.3 3.3 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.3 5.0 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.3 7.0 GO:0042287 MHC protein binding(GO:0042287)
0.3 2.3 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.3 5.6 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.3 11.0 GO:0019894 kinesin binding(GO:0019894)
0.3 11.2 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.3 1.4 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.3 3.0 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.3 0.8 GO:0086077 gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
0.3 1.9 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.3 6.6 GO:0008327 methyl-CpG binding(GO:0008327)
0.3 1.3 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.3 21.3 GO:0030674 protein binding, bridging(GO:0030674)
0.3 1.5 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.3 65.3 GO:0005096 GTPase activator activity(GO:0005096)
0.3 3.6 GO:0005537 mannose binding(GO:0005537)
0.3 1.5 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.3 5.3 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.2 4.4 GO:0050681 androgen receptor binding(GO:0050681)
0.2 3.1 GO:0008143 poly(A) binding(GO:0008143)
0.2 12.3 GO:0015631 tubulin binding(GO:0015631)
0.2 3.3 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.2 1.9 GO:0004970 ionotropic glutamate receptor activity(GO:0004970)
0.2 5.2 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.2 70.5 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.2 39.8 GO:0042277 peptide binding(GO:0042277)
0.2 13.4 GO:0017137 Rab GTPase binding(GO:0017137)
0.2 1.5 GO:0031419 cobalamin binding(GO:0031419)
0.2 1.7 GO:0008417 fucosyltransferase activity(GO:0008417)
0.2 8.5 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.2 5.4 GO:0008009 chemokine activity(GO:0008009)
0.2 145.4 GO:0042803 protein homodimerization activity(GO:0042803)
0.2 2.2 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.2 1.8 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.2 4.1 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.2 2.5 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.2 1.4 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.2 0.8 GO:0015245 fatty acid transporter activity(GO:0015245)
0.2 0.8 GO:1990226 histone methyltransferase binding(GO:1990226)
0.2 12.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.2 1.6 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.2 3.3 GO:0005507 copper ion binding(GO:0005507)
0.2 1.8 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.2 0.8 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.1 1.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 0.9 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.1 0.9 GO:0001515 opioid peptide activity(GO:0001515)
0.1 1.0 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.1 1.6 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 4.6 GO:0015485 cholesterol binding(GO:0015485)
0.1 5.6 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)
0.1 1.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 2.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.3 GO:0051378 serotonin binding(GO:0051378)
0.1 1.2 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.1 17.6 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.1 0.5 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.1 2.6 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 21.8 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.1 0.6 GO:0015643 toxic substance binding(GO:0015643)
0.1 3.1 GO:0001671 ATPase activator activity(GO:0001671)
0.1 1.6 GO:0008536 Ran GTPase binding(GO:0008536)
0.1 1.4 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 2.8 GO:0030515 snoRNA binding(GO:0030515)
0.1 3.6 GO:0032947 protein complex scaffold(GO:0032947)
0.1 6.6 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.1 0.5 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.1 3.4 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 0.6 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 0.7 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.1 1.0 GO:0036442 hydrogen-exporting ATPase activity(GO:0036442) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1 1.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 0.5 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 1.9 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 0.3 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.1 5.8 GO:0030246 carbohydrate binding(GO:0030246)
0.1 0.2 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 1.1 GO:0070064 proline-rich region binding(GO:0070064)
0.1 1.7 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 0.4 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 4.2 GO:0016779 nucleotidyltransferase activity(GO:0016779)
0.0 1.1 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.0 2.5 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 1.8 GO:0008374 O-acyltransferase activity(GO:0008374)
0.0 3.1 GO:0008236 serine-type peptidase activity(GO:0008236)
0.0 0.1 GO:0042284 sphingolipid delta-4 desaturase activity(GO:0042284)
0.0 0.2 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.1 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.4 GO:0050699 WW domain binding(GO:0050699)
0.0 0.3 GO:0017022 myosin binding(GO:0017022)
0.0 0.1 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.3 GO:0048306 calcium-dependent protein binding(GO:0048306)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 95.8 PID_MAPK_TRK_PATHWAY Trk receptor signaling mediated by the MAPK pathway
1.6 88.5 PID_REELIN_PATHWAY Reelin signaling pathway
1.3 2.6 PID_ER_NONGENOMIC_PATHWAY Plasma membrane estrogen receptor signaling
1.0 40.5 SIG_CD40PATHWAYMAP Genes related to CD40 signaling
1.0 32.0 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.9 32.6 PID_ALK1_PATHWAY ALK1 signaling events
0.9 14.5 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.9 21.2 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.9 23.0 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.8 60.3 PID_LKB1_PATHWAY LKB1 signaling events
0.8 78.0 PID_CMYB_PATHWAY C-MYB transcription factor network
0.8 13.0 SA_PTEN_PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.8 17.6 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.8 32.4 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.7 8.2 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.7 19.5 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.7 17.8 PID_IL3_PATHWAY IL3-mediated signaling events
0.7 26.9 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.6 9.5 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.5 15.6 PID_KIT_PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.5 22.9 PID_FGF_PATHWAY FGF signaling pathway
0.5 26.1 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity
0.5 10.7 PID_ANGIOPOIETIN_RECEPTOR_PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.5 4.3 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.5 17.5 PID_BMP_PATHWAY BMP receptor signaling
0.5 15.8 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events
0.5 10.6 PID_MYC_PATHWAY C-MYC pathway
0.5 5.0 PID_RANBP2_PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.4 11.2 PID_IL4_2PATHWAY IL4-mediated signaling events
0.4 11.2 PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY Signaling mediated by p38-alpha and p38-beta
0.4 14.8 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.4 16.1 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.4 5.5 ST_GRANULE_CELL_SURVIVAL_PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.4 9.5 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.4 7.0 ST_G_ALPHA_I_PATHWAY G alpha i Pathway
0.4 3.3 PID_SYNDECAN_2_PATHWAY Syndecan-2-mediated signaling events
0.4 22.9 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.3 10.7 PID_TNF_PATHWAY TNF receptor signaling pathway
0.3 20.5 PID_PDGFRB_PATHWAY PDGFR-beta signaling pathway
0.3 3.8 PID_ERBB2_ERBB3_PATHWAY ErbB2/ErbB3 signaling events
0.3 1.3 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.3 1.9 PID_IL2_PI3K_PATHWAY IL2 signaling events mediated by PI3K
0.3 10.7 PID_REG_GR_PATHWAY Glucocorticoid receptor regulatory network
0.2 3.6 PID_TCPTP_PATHWAY Signaling events mediated by TCPTP
0.2 2.4 PID_AR_NONGENOMIC_PATHWAY Nongenotropic Androgen signaling
0.2 8.7 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.2 1.3 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.2 8.3 ST_INTEGRIN_SIGNALING_PATHWAY Integrin Signaling Pathway
0.2 4.6 PID_P75_NTR_PATHWAY p75(NTR)-mediated signaling
0.2 5.5 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.2 1.7 ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY PI3K Pathway
0.2 0.3 PID_ERBB1_RECEPTOR_PROXIMAL_PATHWAY EGF receptor (ErbB1) signaling pathway
0.1 1.7 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.1 4.3 PID_TGFBR_PATHWAY TGF-beta receptor signaling
0.1 1.0 PID_NECTIN_PATHWAY Nectin adhesion pathway
0.1 15.0 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 1.4 PID_ERBB4_PATHWAY ErbB4 signaling events
0.1 0.7 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.1 1.3 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 0.3 PID_PTP1B_PATHWAY Signaling events mediated by PTP1B
0.0 0.5 PID_LYSOPHOSPHOLIPID_PATHWAY LPA receptor mediated events
0.0 0.6 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.0 1.4 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.0 5.0 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.0 2.4 PID_P53_DOWNSTREAM_PATHWAY Direct p53 effectors
0.0 0.4 PID_RAC1_PATHWAY RAC1 signaling pathway
0.0 0.6 PID_RB_1PATHWAY Regulation of retinoblastoma protein
0.0 0.9 PID_P53_REGULATION_PATHWAY p53 pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
9.2 36.7 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
5.2 52.5 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
3.6 69.2 REACTOME_LIGAND_GATED_ION_CHANNEL_TRANSPORT Genes involved in Ligand-gated ion channel transport
3.3 104.4 REACTOME_ERK_MAPK_TARGETS Genes involved in ERK/MAPK targets
3.1 117.7 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
3.0 107.9 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
2.9 77.8 REACTOME_UNBLOCKING_OF_NMDA_RECEPTOR_GLUTAMATE_BINDING_AND_ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
2.4 4.8 REACTOME_SIGNALLING_BY_NGF Genes involved in Signalling by NGF
1.8 63.8 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
1.8 23.6 REACTOME_PLATELET_CALCIUM_HOMEOSTASIS Genes involved in Platelet calcium homeostasis
1.5 20.9 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
1.5 33.8 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
1.4 15.4 REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
1.4 33.1 REACTOME_CA_DEPENDENT_EVENTS Genes involved in Ca-dependent events
1.1 14.7 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
1.1 38.9 REACTOME_LYSOSOME_VESICLE_BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
1.0 19.7 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
1.0 73.2 REACTOME_L1CAM_INTERACTIONS Genes involved in L1CAM interactions
0.9 15.0 REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.9 34.8 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.9 21.5 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.8 7.5 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.8 18.2 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.8 23.1 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.8 2.4 REACTOME_HORMONE_LIGAND_BINDING_RECEPTORS Genes involved in Hormone ligand-binding receptors
0.8 4.0 REACTOME_VIF_MEDIATED_DEGRADATION_OF_APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.7 22.3 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.7 7.9 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.7 10.5 REACTOME_HYALURONAN_METABOLISM Genes involved in Hyaluronan metabolism
0.7 3.5 REACTOME_DSCAM_INTERACTIONS Genes involved in DSCAM interactions
0.7 8.5 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.6 15.6 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.6 4.4 REACTOME_SIGNALING_BY_ACTIVATED_POINT_MUTANTS_OF_FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.6 7.1 REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.6 43.9 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.6 4.0 REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING Genes involved in Sema4D in semaphorin signaling
0.5 13.2 REACTOME_TRANSPORT_TO_THE_GOLGI_AND_SUBSEQUENT_MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.5 4.0 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.5 13.2 REACTOME_RNA_POL_III_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.5 18.9 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.5 7.6 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.5 16.9 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.5 4.6 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.5 42.8 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.4 2.7 REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE_ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.4 3.9 REACTOME_TRYPTOPHAN_CATABOLISM Genes involved in Tryptophan catabolism
0.4 3.4 REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.4 11.9 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.4 6.3 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.3 2.7 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.3 4.6 REACTOME_REGULATION_OF_KIT_SIGNALING Genes involved in Regulation of KIT signaling
0.3 3.6 REACTOME_ACTIVATION_OF_CHAPERONES_BY_ATF6_ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.3 4.2 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.3 2.5 REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.3 34.6 REACTOME_G_ALPHA_I_SIGNALLING_EVENTS Genes involved in G alpha (i) signalling events
0.3 6.8 REACTOME_ENOS_ACTIVATION_AND_REGULATION Genes involved in eNOS activation and regulation
0.3 11.5 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.2 3.3 REACTOME_FORMATION_OF_TRANSCRIPTION_COUPLED_NER_TC_NER_REPAIR_COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.2 5.7 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.2 3.2 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.2 1.8 REACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.2 13.1 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.2 2.5 REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.2 0.8 REACTOME_DESTABILIZATION_OF_MRNA_BY_AUF1_HNRNP_D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.2 3.6 REACTOME_REGULATORY_RNA_PATHWAYS Genes involved in Regulatory RNA pathways
0.2 3.6 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.1 1.3 REACTOME_PYRIMIDINE_CATABOLISM Genes involved in Pyrimidine catabolism
0.1 4.7 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.1 2.3 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.1 6.0 REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.1 0.3 REACTOME_NOREPINEPHRINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 3.9 REACTOME_ION_CHANNEL_TRANSPORT Genes involved in Ion channel transport
0.1 1.0 REACTOME_SHC1_EVENTS_IN_ERBB4_SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.1 1.9 REACTOME_METABOLISM_OF_STEROID_HORMONES_AND_VITAMINS_A_AND_D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.1 2.8 REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 1.3 REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1 9.6 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.1 0.8 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 1.2 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 6.0 REACTOME_CYCLIN_E_ASSOCIATED_EVENTS_DURING_G1_S_TRANSITION_ Genes involved in Cyclin E associated events during G1/S transition
0.1 1.9 REACTOME_SIGNALING_BY_FGFR1_MUTANTS Genes involved in Signaling by FGFR1 mutants
0.1 0.9 REACTOME_PROLONGED_ERK_ACTIVATION_EVENTS Genes involved in Prolonged ERK activation events
0.1 4.7 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 1.4 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.1 0.6 REACTOME_REGULATION_OF_IFNG_SIGNALING Genes involved in Regulation of IFNG signaling
0.1 0.6 REACTOME_GLUCOSE_TRANSPORT Genes involved in Glucose transport
0.1 0.8 REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 Genes involved in Nuclear signaling by ERBB4
0.1 1.5 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.8 REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.3 REACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.4 REACTOME_SIGNALING_BY_EGFR_IN_CANCER Genes involved in Signaling by EGFR in Cancer
0.0 1.9 REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION Genes involved in MHC class II antigen presentation
0.0 1.1 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.3 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.0 0.8 REACTOME_NGF_SIGNALLING_VIA_TRKA_FROM_THE_PLASMA_MEMBRANE Genes involved in NGF signalling via TRKA from the plasma membrane
0.0 0.4 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.3 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.1 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.0 REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication