Motif ID: Hoxd9

Z-value: 0.580


Transcription factors associated with Hoxd9:

Gene SymbolEntrez IDGene Name
Hoxd9 ENSMUSG00000043342.8 Hoxd9



Activity profile for motif Hoxd9.

activity profile for motif Hoxd9


Sorted Z-values histogram for motif Hoxd9

Sorted Z-values for motif Hoxd9



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxd9

PNG image of the network

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Top targets:


Showing 1 to 20 of 107 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_36811361 5.853 ENSMUST00000101534.1
 Ptn
pleiotrophin
chrX_+_82948861 5.518 ENSMUST00000114000.1
 Dmd
dystrophin, muscular dystrophy
chr8_+_84723003 4.698 ENSMUST00000098571.4
 G430095P16Rik
RIKEN cDNA G430095P16 gene
chr7_-_103827922 3.987 ENSMUST00000023934.6
ENSMUST00000153218.1
 Hbb-bs

hemoglobin, beta adult s chain

chr2_-_63184253 3.460 ENSMUST00000075052.3
ENSMUST00000112454.1
 Kcnh7

potassium voltage-gated channel, subfamily H (eag-related), member 7

chr5_-_77408034 3.342 ENSMUST00000163898.1
ENSMUST00000046746.6
 Igfbp7

insulin-like growth factor binding protein 7

chr3_+_35754121 3.326 ENSMUST00000108186.1
ENSMUST00000029257.8
 Atp11b

ATPase, class VI, type 11B

chr3_-_116129615 3.307 ENSMUST00000029574.8
 Vcam1
vascular cell adhesion molecule 1
chrX_+_85048309 3.236 ENSMUST00000113991.1
ENSMUST00000113992.2
 Dmd

dystrophin, muscular dystrophy

chr11_+_29373618 3.161 ENSMUST00000040182.6
ENSMUST00000109477.1
 Ccdc88a

coiled coil domain containing 88A

chr3_+_114030532 3.114 ENSMUST00000123619.1
ENSMUST00000092155.5
 Col11a1

collagen, type XI, alpha 1

chr13_-_74376566 2.987 ENSMUST00000091481.2
 Zfp72
zinc finger protein 72
chr7_+_66365905 2.800 ENSMUST00000107486.1
 Gm10974
predicted gene 10974
chr3_-_49757257 2.608 ENSMUST00000035931.7
 Pcdh18
protocadherin 18
chr8_+_66386292 2.437 ENSMUST00000039540.5
ENSMUST00000110253.2
 March1

membrane-associated ring finger (C3HC4) 1

chr2_+_67748212 2.268 ENSMUST00000180887.1
 B3galt1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr13_-_105271039 2.223 ENSMUST00000069686.6
 Rnf180
ring finger protein 180
chr17_-_78684262 2.143 ENSMUST00000145480.1
 Strn
striatin, calmodulin binding protein
chr2_-_63184170 2.071 ENSMUST00000112452.1
 Kcnh7
potassium voltage-gated channel, subfamily H (eag-related), member 7
chr19_-_29753600 2.028 ENSMUST00000175764.1
 9930021J03Rik
RIKEN cDNA 9930021J03 gene

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 52 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.9 8.8 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
2.0 5.9 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.0 5.8 GO:0071805 potassium ion transmembrane transport(GO:0071805)
0.1 4.6 GO:0030032 lamellipodium assembly(GO:0030032)
0.3 3.3 GO:0061032 visceral serous pericardium development(GO:0061032)
0.0 3.3 GO:0050810 regulation of steroid biosynthetic process(GO:0050810)
0.6 3.2 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.5 3.1 GO:0035989 tendon development(GO:0035989)
0.4 3.0 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.1 2.6 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.3 2.4 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.1 2.4 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.3 2.3 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.2 2.2 GO:0042415 norepinephrine metabolic process(GO:0042415)
0.0 1.9 GO:0008542 visual learning(GO:0008542)
0.3 1.8 GO:1903056 positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.0 1.8 GO:0001578 microtubule bundle formation(GO:0001578)
0.3 1.6 GO:1901979 regulation of inward rectifier potassium channel activity(GO:1901979)
0.1 1.6 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.1 1.6 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 26 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 11.0 GO:0005887 integral component of plasma membrane(GO:0005887)
0.5 9.1 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 6.5 GO:0031594 neuromuscular junction(GO:0031594)
0.0 4.4 GO:0042641 actomyosin(GO:0042641)
1.0 4.0 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 3.3 GO:0002102 podosome(GO:0002102)
0.0 3.2 GO:0005814 centriole(GO:0005814)
0.3 3.1 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 2.7 GO:0055037 recycling endosome(GO:0055037)
0.1 2.4 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 2.4 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.1 2.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 2.2 GO:0031227 intrinsic component of endoplasmic reticulum membrane(GO:0031227)
0.0 1.6 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.3 1.4 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.4 1.3 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 1.2 GO:0097539 ciliary transition fiber(GO:0097539)
0.1 1.0 GO:0000815 ESCRT III complex(GO:0000815)
0.0 1.0 GO:0072562 blood microparticle(GO:0072562)
0.1 0.9 GO:0017119 Golgi transport complex(GO:0017119)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 41 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 8.8 GO:0002162 dystroglycan binding(GO:0002162)
0.4 7.4 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
2.0 5.9 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.0 5.0 GO:0003779 actin binding(GO:0003779)
1.0 4.0 GO:0031721 haptoglobin binding(GO:0031720) hemoglobin alpha binding(GO:0031721)
0.8 3.3 GO:0008131 primary amine oxidase activity(GO:0008131)
0.2 3.3 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 3.3 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 3.2 GO:0043422 protein kinase B binding(GO:0043422)
0.1 3.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.3 2.4 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1 2.4 GO:0042287 MHC protein binding(GO:0042287)
0.6 2.3 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.1 2.2 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 2.1 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 2.1 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 1.8 GO:0070412 R-SMAD binding(GO:0070412)
0.1 1.6 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.2 1.5 GO:0098821 BMP receptor activity(GO:0098821)
0.0 1.5 GO:0005504 fatty acid binding(GO:0005504)

Gene overrepresentation in C2:CP category:

Showing 1 to 12 of 12 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 5.9 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.2 3.3 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.0 3.3 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 3.1 NABA_COLLAGENS Genes encoding collagen proteins
0.1 2.1 PID_ARF6_PATHWAY Arf6 signaling events
0.1 2.1 PID_ER_NONGENOMIC_PATHWAY Plasma membrane estrogen receptor signaling
0.0 1.6 PID_CDC42_PATHWAY CDC42 signaling events
0.0 1.5 PID_BMP_PATHWAY BMP receptor signaling
0.1 1.4 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 1.3 PID_IL5_PATHWAY IL5-mediated signaling events
0.0 0.9 PID_AURORA_A_PATHWAY Aurora A signaling
0.0 0.6 PID_ENDOTHELIN_PATHWAY Endothelins

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 17 of 17 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 8.8 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.1 5.5 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.2 4.6 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.2 3.3 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 3.3 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.1 3.1 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 2.1 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.1 1.9 REACTOME_DOWNSTREAM_TCR_SIGNALING Genes involved in Downstream TCR signaling
0.1 1.4 REACTOME_MTORC1_MEDIATED_SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 1.4 REACTOME_RNA_POL_I_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.1 1.2 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.1 1.1 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.2 1.0 REACTOME_REGULATION_OF_COMPLEMENT_CASCADE Genes involved in Regulation of Complement cascade
0.0 1.0 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.9 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.6 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.4 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors