Motif ID: Hsf2

Z-value: 1.339


Transcription factors associated with Hsf2:

Gene SymbolEntrez IDGene Name
Hsf2 ENSMUSG00000019878.7 Hsf2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hsf2mm10_v2_chr10_+_57486354_574864140.569.5e-08Click!


Activity profile for motif Hsf2.

activity profile for motif Hsf2


Sorted Z-values histogram for motif Hsf2

Sorted Z-values for motif Hsf2



Network of associatons between targets according to the STRING database.



First level regulatory network of Hsf2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_-_92164666 16.643 ENSMUST00000183123.1
ENSMUST00000182033.1
Rmst

rhabdomyosarcoma 2 associated transcript (non-coding RNA)

chr1_-_138847579 12.740 ENSMUST00000093486.3
ENSMUST00000046870.6
Lhx9

LIM homeobox protein 9

chr1_+_136467958 10.792 ENSMUST00000047817.6
Kif14
kinesin family member 14
chr1_+_138963709 10.716 ENSMUST00000168527.1
Dennd1b
DENN/MADD domain containing 1B
chr13_+_51645232 10.536 ENSMUST00000075853.5
Cks2
CDC28 protein kinase regulatory subunit 2
chr4_-_53159885 10.341 ENSMUST00000030010.3
Abca1
ATP-binding cassette, sub-family A (ABC1), member 1
chr7_-_4752972 10.275 ENSMUST00000183971.1
ENSMUST00000182173.1
ENSMUST00000182738.1
ENSMUST00000184143.1
ENSMUST00000182111.1
ENSMUST00000182048.1
ENSMUST00000063324.7
Cox6b2






cytochrome c oxidase subunit VIb polypeptide 2






chr11_-_11970540 9.663 ENSMUST00000109653.1
Grb10
growth factor receptor bound protein 10
chr17_-_70849644 9.630 ENSMUST00000134654.1
ENSMUST00000172229.1
ENSMUST00000127719.1
Tgif1


TGFB-induced factor homeobox 1


chr8_-_110168204 9.611 ENSMUST00000003754.6
Calb2
calbindin 2
chr15_+_57694651 9.352 ENSMUST00000096430.4
Zhx2
zinc fingers and homeoboxes 2
chr17_-_70851189 9.064 ENSMUST00000059775.8
Tgif1
TGFB-induced factor homeobox 1
chr4_+_128883549 9.017 ENSMUST00000035667.8
Trim62
tripartite motif-containing 62
chr17_-_34972124 8.675 ENSMUST00000087328.2
ENSMUST00000179128.1
Hspa1a

heat shock protein 1A

chr5_+_135887988 8.653 ENSMUST00000111155.1
Hspb1
heat shock protein 1
chr3_+_94342092 8.612 ENSMUST00000029794.5
Them5
thioesterase superfamily member 5
chr10_-_92165159 8.583 ENSMUST00000182567.1
ENSMUST00000181604.2
ENSMUST00000181213.1
Rmst


rhabdomyosarcoma 2 associated transcript (non-coding RNA)


chr5_+_135887905 8.444 ENSMUST00000005077.6
Hspb1
heat shock protein 1
chr5_+_17574726 8.440 ENSMUST00000169603.1
Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr5_+_92683625 8.352 ENSMUST00000168878.1
Shroom3
shroom family member 3
chr11_+_43528759 8.315 ENSMUST00000050574.6
Ccnjl
cyclin J-like
chr2_+_152847961 8.136 ENSMUST00000164120.1
ENSMUST00000178997.1
ENSMUST00000109816.1
Tpx2


TPX2, microtubule-associated protein homolog (Xenopus laevis)


chr3_-_127780461 8.035 ENSMUST00000029662.5
ENSMUST00000161239.1
Alpk1

alpha-kinase 1

chr16_-_45844228 7.853 ENSMUST00000076333.5
Phldb2
pleckstrin homology-like domain, family B, member 2
chr5_+_17574268 7.823 ENSMUST00000030568.7
Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr15_+_25773985 7.817 ENSMUST00000125667.1
Myo10
myosin X
chr11_-_100939357 7.762 ENSMUST00000092671.5
ENSMUST00000103114.1
Stat3

signal transducer and activator of transcription 3

chr2_+_152847993 7.644 ENSMUST00000028969.8
Tpx2
TPX2, microtubule-associated protein homolog (Xenopus laevis)
chr14_-_65833963 7.614 ENSMUST00000022613.9
Esco2
establishment of cohesion 1 homolog 2 (S. cerevisiae)
chr1_-_119053619 7.548 ENSMUST00000062483.8
Gli2
GLI-Kruppel family member GLI2
chr14_+_28504736 7.467 ENSMUST00000063465.4
Wnt5a
wingless-related MMTV integration site 5A
chr16_-_45844303 7.414 ENSMUST00000036355.6
Phldb2
pleckstrin homology-like domain, family B, member 2
chr6_+_134929089 7.374 ENSMUST00000183867.1
ENSMUST00000184991.1
ENSMUST00000183905.1
RP23-45G16.5


RP23-45G16.5


chr5_-_5514730 7.326 ENSMUST00000115445.1
ENSMUST00000179804.1
ENSMUST00000125110.1
ENSMUST00000115446.1
Cldn12



claudin 12



chr8_+_70863127 7.276 ENSMUST00000050921.2
A230052G05Rik
RIKEN cDNA A230052G05 gene
chr2_-_91931675 7.266 ENSMUST00000111309.1
Mdk
midkine
chr9_-_72111172 7.204 ENSMUST00000183992.1
Tcf12
transcription factor 12
chr7_-_118995211 7.195 ENSMUST00000008878.8
Gprc5b
G protein-coupled receptor, family C, group 5, member B
chr17_-_25797032 6.984 ENSMUST00000165838.1
ENSMUST00000002344.6
Metrn

meteorin, glial cell differentiation regulator

chr2_-_91931696 6.718 ENSMUST00000090602.5
Mdk
midkine
chr4_+_59626189 6.686 ENSMUST00000070150.4
ENSMUST00000052420.6
E130308A19Rik

RIKEN cDNA E130308A19 gene

chr2_-_28466266 6.578 ENSMUST00000127683.1
ENSMUST00000086370.4
1700007K13Rik

RIKEN cDNA 1700007K13 gene

chr2_-_59948155 6.539 ENSMUST00000153136.1
Baz2b
bromodomain adjacent to zinc finger domain, 2B
chrX_+_161717055 6.460 ENSMUST00000112338.1
Rai2
retinoic acid induced 2
chr9_+_15520830 6.456 ENSMUST00000178999.1
Smco4
single-pass membrane protein with coiled-coil domains 4
chr2_-_26503814 6.397 ENSMUST00000028288.4
Notch1
notch 1
chr7_+_127211608 6.330 ENSMUST00000032910.6
Mylpf
myosin light chain, phosphorylatable, fast skeletal muscle
chr6_-_39206782 6.190 ENSMUST00000002305.8
Jhdm1d
jumonji C domain-containing histone demethylase 1 homolog D (S. cerevisiae)
chr5_-_5514873 6.177 ENSMUST00000060947.7
Cldn12
claudin 12
chr9_+_65141154 6.145 ENSMUST00000034961.4
Igdcc3
immunoglobulin superfamily, DCC subclass, member 3
chr9_+_72438519 6.122 ENSMUST00000184604.1
Mns1
meiosis-specific nuclear structural protein 1
chr18_+_50053282 6.119 ENSMUST00000148159.2
Tnfaip8
tumor necrosis factor, alpha-induced protein 8
chr11_+_34314757 5.975 ENSMUST00000165963.1
ENSMUST00000093192.3
Fam196b

family with sequence similarity 196, member B

chr7_+_114745685 5.955 ENSMUST00000136645.1
ENSMUST00000169913.1
Insc

inscuteable homolog (Drosophila)

chr14_-_48667508 5.942 ENSMUST00000144465.1
ENSMUST00000133479.1
ENSMUST00000119070.1
ENSMUST00000152018.1
Otx2



orthodenticle homolog 2 (Drosophila)



chr2_-_172370506 5.824 ENSMUST00000109139.1
ENSMUST00000028997.7
ENSMUST00000109140.3
Aurka


aurora kinase A


chr5_-_120472763 5.732 ENSMUST00000052258.7
ENSMUST00000031594.6
Sdsl

serine dehydratase-like

chr5_+_30105161 5.451 ENSMUST00000058045.4
Gareml
GRB2 associated, regulator of MAPK1-like
chr10_-_80421847 5.322 ENSMUST00000156244.1
Tcf3
transcription factor 3
chr4_-_107923519 5.282 ENSMUST00000106719.1
ENSMUST00000106720.2
ENSMUST00000131644.1
ENSMUST00000030345.8
Cpt2



carnitine palmitoyltransferase 2



chr4_-_45532470 5.230 ENSMUST00000147448.1
Shb
src homology 2 domain-containing transforming protein B
chr3_-_10208569 5.219 ENSMUST00000029041.4
Fabp4
fatty acid binding protein 4, adipocyte
chr2_+_35109482 5.151 ENSMUST00000028235.4
ENSMUST00000156933.1
ENSMUST00000028237.8
Cep110


centrosomal protein 110


chr7_-_99353104 5.094 ENSMUST00000169437.1
ENSMUST00000094154.4
Serpinh1

serine (or cysteine) peptidase inhibitor, clade H, member 1

chr7_+_83631959 5.080 ENSMUST00000075418.7
ENSMUST00000117410.1
Stard5

StAR-related lipid transfer (START) domain containing 5

chr7_+_75610038 5.058 ENSMUST00000125771.1
Akap13
A kinase (PRKA) anchor protein 13
chr12_-_98901478 5.035 ENSMUST00000065716.6
Eml5
echinoderm microtubule associated protein like 5
chr10_+_128092771 4.968 ENSMUST00000170054.2
ENSMUST00000045621.8
Baz2a

bromodomain adjacent to zinc finger domain, 2A

chr6_-_95718800 4.905 ENSMUST00000079847.5
Suclg2
succinate-Coenzyme A ligase, GDP-forming, beta subunit
chr11_-_115813621 4.902 ENSMUST00000041684.4
ENSMUST00000156812.1
Caskin2

CASK-interacting protein 2

chr1_-_133424377 4.878 ENSMUST00000153799.1
Sox13
SRY-box containing gene 13
chr8_+_45507768 4.822 ENSMUST00000067065.7
ENSMUST00000098788.3
ENSMUST00000067107.7
ENSMUST00000171337.2
ENSMUST00000138049.1
ENSMUST00000141039.1
Sorbs2





sorbin and SH3 domain containing 2





chr7_+_112679314 4.812 ENSMUST00000084705.5
ENSMUST00000059768.10
Tead1

TEA domain family member 1

chr4_-_147936713 4.779 ENSMUST00000105712.1
ENSMUST00000019199.7
Plod1

procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1

chr9_+_7764041 4.765 ENSMUST00000052865.9
Tmem123
transmembrane protein 123
chr6_-_142507805 4.750 ENSMUST00000134191.1
ENSMUST00000032373.5
Ldhb

lactate dehydrogenase B

chr10_-_81349085 4.718 ENSMUST00000141171.1
Hmg20b
high mobility group 20B
chr5_+_111733924 4.666 ENSMUST00000180627.1
Gm26897
predicted gene, 26897
chr17_-_15375969 4.639 ENSMUST00000014917.7
Dll1
delta-like 1 (Drosophila)
chr7_-_70366735 4.611 ENSMUST00000089565.5
Nr2f2
nuclear receptor subfamily 2, group F, member 2
chr7_+_112679327 4.491 ENSMUST00000106638.2
Tead1
TEA domain family member 1
chr3_-_121171678 4.483 ENSMUST00000170781.1
ENSMUST00000039761.5
ENSMUST00000106467.1
ENSMUST00000106466.3
ENSMUST00000164925.2
Rwdd3




RWD domain containing 3




chr9_-_100571049 4.482 ENSMUST00000093792.2
Slc35g2
solute carrier family 35, member G2
chr10_-_23349887 4.460 ENSMUST00000074366.6
ENSMUST00000092665.4
Eya4

eyes absent 4 homolog (Drosophila)

chr4_-_154097105 4.422 ENSMUST00000105643.1
ENSMUST00000133533.1
ENSMUST00000097762.4
Trp73


transformation related protein 73


chr9_-_97018823 4.361 ENSMUST00000055433.4
Spsb4
splA/ryanodine receptor domain and SOCS box containing 4
chr2_+_52038005 4.230 ENSMUST00000065927.5
Tnfaip6
tumor necrosis factor alpha induced protein 6
chr9_-_114781986 4.152 ENSMUST00000035009.8
ENSMUST00000084867.7
Cmtm7

CKLF-like MARVEL transmembrane domain containing 7

chr16_-_55934845 4.031 ENSMUST00000121129.1
ENSMUST00000023270.7
Cep97

centrosomal protein 97

chr3_+_86224665 4.022 ENSMUST00000107635.1
Lrba
LPS-responsive beige-like anchor
chr4_+_43267165 4.016 ENSMUST00000107942.2
ENSMUST00000102953.3
Atp8b5

ATPase, class I, type 8B, member 5

chr4_-_41695442 4.013 ENSMUST00000102961.3
ENSMUST00000064443.6
Cntfr

ciliary neurotrophic factor receptor

chr12_+_37880700 3.968 ENSMUST00000040500.7
Dgkb
diacylglycerol kinase, beta
chr19_-_10203880 3.890 ENSMUST00000142241.1
ENSMUST00000116542.2
ENSMUST00000025651.5
ENSMUST00000156291.1
Fen1



flap structure specific endonuclease 1



chr2_-_26246707 3.828 ENSMUST00000166349.1
C030048H21Rik
RIKEN cDNA C030048H21 gene
chr2_+_25180737 3.817 ENSMUST00000104999.2
Nrarp
Notch-regulated ankyrin repeat protein
chr16_-_55934797 3.797 ENSMUST00000122280.1
ENSMUST00000121703.2
Cep97

centrosomal protein 97

chr1_-_136234113 3.755 ENSMUST00000120339.1
ENSMUST00000048668.8
5730559C18Rik

RIKEN cDNA 5730559C18 gene

chr19_+_5366764 3.683 ENSMUST00000025759.7
Eif1ad
eukaryotic translation initiation factor 1A domain containing
chr6_-_72235559 3.629 ENSMUST00000042646.7
Atoh8
atonal homolog 8 (Drosophila)
chr10_+_128238034 3.601 ENSMUST00000105245.2
Timeless
timeless circadian clock 1
chr7_-_44815658 3.589 ENSMUST00000107893.1
Atf5
activating transcription factor 5
chr4_+_62965560 3.552 ENSMUST00000030043.6
ENSMUST00000107415.1
ENSMUST00000064814.5
Zfp618


zinc finger protein 618


chr18_-_24020307 3.537 ENSMUST00000153337.1
ENSMUST00000148525.1
Zfp191

zinc finger protein 191

chr13_+_75839868 3.537 ENSMUST00000022082.7
Glrx
glutaredoxin
chr13_+_44729794 3.493 ENSMUST00000172830.1
Jarid2
jumonji, AT rich interactive domain 2
chr12_-_91746020 3.486 ENSMUST00000166967.1
Ston2
stonin 2
chr10_+_41810528 3.478 ENSMUST00000099931.3
Sesn1
sestrin 1
chr5_+_139423151 3.476 ENSMUST00000066211.4
Gper1
G protein-coupled estrogen receptor 1
chr4_+_48539909 3.411 ENSMUST00000061135.1
Msantd3
Myb/SANT-like DNA-binding domain containing 3
chr1_+_104768510 3.403 ENSMUST00000062528.8
Cdh20
cadherin 20
chr4_+_48540067 3.386 ENSMUST00000064807.2
Msantd3
Myb/SANT-like DNA-binding domain containing 3
chr5_-_124354671 3.331 ENSMUST00000031341.4
Cdk2ap1
CDK2 (cyclin-dependent kinase 2)-associated protein 1
chr5_-_137116177 3.301 ENSMUST00000054384.5
ENSMUST00000152207.1
Trim56

tripartite motif-containing 56

chr5_-_62766153 3.242 ENSMUST00000076623.4
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr8_+_95633500 3.237 ENSMUST00000034094.9
Gins3
GINS complex subunit 3 (Psf3 homolog)
chr7_+_127471484 3.205 ENSMUST00000033095.8
Prr14
proline rich 14
chr17_-_25727364 3.193 ENSMUST00000170070.1
ENSMUST00000048054.7
Chtf18

CTF18, chromosome transmission fidelity factor 18

chrY_+_90755657 3.184 ENSMUST00000167967.2
Gm21857
predicted gene, 21857
chrX_-_157568983 3.171 ENSMUST00000065806.4
Yy2
Yy2 transcription factor
chr5_-_5694024 3.128 ENSMUST00000115425.2
ENSMUST00000115427.1
ENSMUST00000115424.2
ENSMUST00000015797.4
Steap2



six transmembrane epithelial antigen of prostate 2



chr17_-_34959232 3.064 ENSMUST00000165202.1
ENSMUST00000172753.1
Hspa1b

heat shock protein 1B

chr9_-_77544870 3.044 ENSMUST00000183873.1
Lrrc1
leucine rich repeat containing 1
chr7_+_25681158 3.034 ENSMUST00000108403.3
B9d2
B9 protein domain 2
chr11_+_120949053 3.021 ENSMUST00000154187.1
ENSMUST00000100130.3
ENSMUST00000129473.1
ENSMUST00000168579.1
Slc16a3



solute carrier family 16 (monocarboxylic acid transporters), member 3



chr15_+_100304782 3.020 ENSMUST00000067752.3
Mettl7a1
methyltransferase like 7A1
chr2_+_59612034 3.014 ENSMUST00000112568.1
ENSMUST00000037526.4
Tanc1

tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1

chr10_+_121033960 2.998 ENSMUST00000020439.4
ENSMUST00000175867.1
Wif1

Wnt inhibitory factor 1

chr3_-_84305385 2.992 ENSMUST00000122849.1
ENSMUST00000132283.1
Trim2

tripartite motif-containing 2

chr7_+_92561141 2.971 ENSMUST00000032842.6
ENSMUST00000085017.4
Ccdc90b

coiled-coil domain containing 90B

chr2_+_120463566 2.959 ENSMUST00000028749.7
ENSMUST00000110721.1
Capn3

calpain 3

chr2_+_31759932 2.950 ENSMUST00000028190.6
Abl1
c-abl oncogene 1, non-receptor tyrosine kinase
chr19_+_25505618 2.947 ENSMUST00000025755.4
Dmrt1
doublesex and mab-3 related transcription factor 1
chr17_-_70851710 2.937 ENSMUST00000166395.2
Tgif1
TGFB-induced factor homeobox 1
chr1_-_193273099 2.900 ENSMUST00000009777.2
G0s2
G0/G1 switch gene 2
chr7_-_140102384 2.896 ENSMUST00000120034.1
ENSMUST00000121115.1
ENSMUST00000026539.7
Fuom


fucose mutarotase


chr14_+_79481164 2.882 ENSMUST00000040131.5
Elf1
E74-like factor 1
chr18_-_53418004 2.813 ENSMUST00000025419.7
Ppic
peptidylprolyl isomerase C
chr11_+_82911253 2.801 ENSMUST00000164945.1
ENSMUST00000018989.7
Unc45b

unc-45 homolog B (C. elegans)

chr6_-_128438673 2.798 ENSMUST00000032508.4
Fkbp4
FK506 binding protein 4
chr13_+_44729535 2.793 ENSMUST00000174068.1
Jarid2
jumonji, AT rich interactive domain 2
chr6_+_53573364 2.784 ENSMUST00000047450.7
Creb5
cAMP responsive element binding protein 5
chr4_-_11254248 2.784 ENSMUST00000044616.3
ENSMUST00000108319.2
ENSMUST00000108318.2
Ints8


integrator complex subunit 8


chr3_+_96161981 2.765 ENSMUST00000054356.9
Mtmr11
myotubularin related protein 11
chr2_+_31759993 2.755 ENSMUST00000124089.1
Abl1
c-abl oncogene 1, non-receptor tyrosine kinase
chr1_+_187215501 2.742 ENSMUST00000097443.3
ENSMUST00000065573.7
ENSMUST00000110943.2
ENSMUST00000044812.5
Gpatch2



G patch domain containing 2



chr15_+_100353149 2.729 ENSMUST00000088142.5
ENSMUST00000176287.1
ENSMUST00000075675.5
Mettl7a2

AB099516
methyltransferase like 7A2

cDNA sequence AB099516
chr10_+_86302854 2.713 ENSMUST00000132307.1
Timp3
tissue inhibitor of metalloproteinase 3
chr4_+_86748526 2.708 ENSMUST00000082026.7
ENSMUST00000045512.8
Dennd4c

DENN/MADD domain containing 4C

chr19_-_58454435 2.697 ENSMUST00000169850.1
Gfra1
glial cell line derived neurotrophic factor family receptor alpha 1
chr1_-_51915901 2.651 ENSMUST00000018561.7
ENSMUST00000114537.2
Myo1b

myosin IB

chr12_+_29938036 2.618 ENSMUST00000122328.1
ENSMUST00000118321.1
Pxdn

peroxidasin homolog (Drosophila)

chr8_-_80739497 2.609 ENSMUST00000043359.8
Smarca5
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
chr9_-_77544829 2.591 ENSMUST00000183734.1
Lrrc1
leucine rich repeat containing 1
chr2_+_144527718 2.579 ENSMUST00000028914.2
ENSMUST00000110017.2
Polr3f

polymerase (RNA) III (DNA directed) polypeptide F

chr1_-_51915968 2.568 ENSMUST00000046390.7
Myo1b
myosin IB
chr4_+_62525369 2.564 ENSMUST00000062145.1
4933430I17Rik
RIKEN cDNA 4933430I17 gene
chr1_-_44101661 2.559 ENSMUST00000152239.1
Tex30
testis expressed 30
chr10_-_127070254 2.557 ENSMUST00000060991.4
Tspan31
tetraspanin 31
chr7_+_16781341 2.555 ENSMUST00000108496.2
Slc1a5
solute carrier family 1 (neutral amino acid transporter), member 5
chr18_-_37997543 2.522 ENSMUST00000042944.7
Arap3
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr12_-_69228167 2.521 ENSMUST00000021359.5
Pole2
polymerase (DNA directed), epsilon 2 (p59 subunit)
chr1_-_79858627 2.518 ENSMUST00000027467.4
Serpine2
serine (or cysteine) peptidase inhibitor, clade E, member 2
chr7_-_141443314 2.514 ENSMUST00000106005.2
Lrdd
leucine-rich and death domain containing
chr17_+_25875492 2.494 ENSMUST00000026827.8
ENSMUST00000169308.1
ENSMUST00000169085.1
ENSMUST00000163356.1
0610011F06Rik



RIKEN cDNA 0610011F06 gene



chrX_+_151522352 2.448 ENSMUST00000148622.1
Phf8
PHD finger protein 8
chr1_-_45503282 2.443 ENSMUST00000086430.4
Col5a2
collagen, type V, alpha 2
chr13_-_92794809 2.433 ENSMUST00000022213.7
Thbs4
thrombospondin 4
chr4_+_109407087 2.387 ENSMUST00000064129.7
ENSMUST00000106619.1
Ttc39a

tetratricopeptide repeat domain 39A

chr16_+_77014069 2.380 ENSMUST00000023580.6
Usp25
ubiquitin specific peptidase 25
chr5_-_5664196 2.374 ENSMUST00000061008.3
ENSMUST00000054865.6
A330021E22Rik

RIKEN cDNA A330021E22 gene

chr19_-_4839286 2.355 ENSMUST00000037246.5
Ccs
copper chaperone for superoxide dismutase
chr17_-_34627148 2.352 ENSMUST00000171376.1
ENSMUST00000169287.1
Ppt2

palmitoyl-protein thioesterase 2

chr13_-_98926374 2.344 ENSMUST00000109401.1
Tnpo1
transportin 1
chr2_-_125625065 2.335 ENSMUST00000089776.2
Cep152
centrosomal protein 152
chr13_-_3918157 2.312 ENSMUST00000091853.4
Net1
neuroepithelial cell transforming gene 1
chr14_+_31495065 2.291 ENSMUST00000022446.5
Eaf1
ELL associated factor 1
chr17_+_44188564 2.234 ENSMUST00000024755.5
Clic5
chloride intracellular channel 5
chr9_-_65580040 2.201 ENSMUST00000068944.7
Plekho2
pleckstrin homology domain containing, family O member 2
chr19_-_8774431 2.195 ENSMUST00000010249.5
Tmem179b
transmembrane protein 179B
chr14_-_118132763 2.188 ENSMUST00000022727.8
Tgds
TDP-glucose 4,6-dehydratase
chr17_-_23771543 2.185 ENSMUST00000086325.5
Flywch1
FLYWCH-type zinc finger 1
chr18_-_47368446 2.170 ENSMUST00000076043.6
ENSMUST00000135790.1
Sema6a

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A

chr2_-_181599128 2.161 ENSMUST00000060173.8
Samd10
sterile alpha motif domain containing 10
chr8_+_47533639 2.156 ENSMUST00000033973.7
ENSMUST00000176379.1
Rwdd4a

RWD domain containing 4A

chr14_-_101609033 2.147 ENSMUST00000161991.1
ENSMUST00000100340.3
Tbc1d4

TBC1 domain family, member 4

chr5_-_50058908 2.136 ENSMUST00000030971.5
Gpr125
G protein-coupled receptor 125
chr5_-_116422858 2.115 ENSMUST00000036991.4
Hspb8
heat shock protein 8
chr2_-_161109017 2.105 ENSMUST00000039782.7
ENSMUST00000134178.1
Chd6

chromodomain helicase DNA binding protein 6

chr3_+_127789872 2.084 ENSMUST00000054483.7
ENSMUST00000163775.1
Tifa

TRAF-interacting protein with forkhead-associated domain

chr18_+_61953048 2.074 ENSMUST00000051720.5
Sh3tc2
SH3 domain and tetratricopeptide repeats 2
chr6_-_92943485 2.063 ENSMUST00000113438.1
Adamts9
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 9
chr3_+_88629442 2.041 ENSMUST00000176316.1
ENSMUST00000176879.1
Arhgef2

rho/rac guanine nucleotide exchange factor (GEF) 2

chr17_-_34627365 2.031 ENSMUST00000064953.8
ENSMUST00000170345.1
ENSMUST00000171121.2
ENSMUST00000168391.2
ENSMUST00000169067.2
Ppt2




palmitoyl-protein thioesterase 2




chr4_+_131873608 2.029 ENSMUST00000053819.3
Srsf4
serine/arginine-rich splicing factor 4
chr10_+_68723723 2.010 ENSMUST00000080995.6
Tmem26
transmembrane protein 26
chr9_+_66126611 1.983 ENSMUST00000034945.5
Fam96a
family with sequence similarity 96, member A
chr6_+_128438757 1.962 ENSMUST00000144745.1
Gm10069
predicted gene 10069
chr5_+_32611171 1.959 ENSMUST00000072311.6
ENSMUST00000168707.2
Yes1

Yamaguchi sarcoma viral (v-yes) oncogene homolog 1

chr19_-_28967794 1.951 ENSMUST00000162110.1
4430402I18Rik
RIKEN cDNA 4430402I18 gene

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
4.7 14.0 GO:0030421 defecation(GO:0030421)
3.9 15.4 GO:0021698 cerebellar cortex structural organization(GO:0021698)
3.0 17.8 GO:0042535 positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
2.8 13.9 GO:0003213 cardiac right atrium morphogenesis(GO:0003213)
2.7 16.3 GO:0003350 pulmonary myocardium development(GO:0003350)
2.6 10.3 GO:0055099 response to high density lipoprotein particle(GO:0055099) platelet dense granule organization(GO:0060155)
2.5 12.7 GO:0035262 gonad morphogenesis(GO:0035262)
2.2 15.3 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
1.9 7.8 GO:1902724 positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
1.9 5.7 GO:1900275 negative regulation of phospholipase C activity(GO:1900275)
1.9 7.5 GO:0060032 notochord regression(GO:0060032)
1.6 11.1 GO:0035745 T-helper 2 cell cytokine production(GO:0035745)
1.5 7.6 GO:0034421 post-translational protein acetylation(GO:0034421)
1.5 4.5 GO:1902071 positive regulation of cellular response to hypoxia(GO:1900039) regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
1.5 5.9 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
1.5 5.8 GO:0007056 spindle assembly involved in female meiosis(GO:0007056) positive regulation of oocyte development(GO:0060282)
1.4 21.6 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
1.3 4.0 GO:0003360 brainstem development(GO:0003360)
1.2 3.6 GO:1904975 response to bleomycin(GO:1904975) cellular response to bleomycin(GO:1904976)
1.2 4.8 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
1.1 4.4 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
1.1 9.7 GO:0070874 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
1.1 3.2 GO:0002489 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489)
1.0 4.2 GO:0002337 B-1a B cell differentiation(GO:0002337)
1.0 9.3 GO:0014883 transition between fast and slow fiber(GO:0014883)
1.0 7.2 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
1.0 3.0 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
1.0 4.8 GO:0019244 lactate biosynthetic process from pyruvate(GO:0019244)
0.9 4.6 GO:0060849 regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.9 2.7 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.9 5.3 GO:0002326 B cell lineage commitment(GO:0002326)
0.9 3.5 GO:1904706 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579) negative regulation of vascular smooth muscle cell proliferation(GO:1904706) positive regulation of vascular smooth muscle cell differentiation(GO:1905065)
0.8 5.1 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.8 2.5 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.8 2.4 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.8 2.4 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.8 2.4 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.7 3.5 GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.7 23.6 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.7 9.6 GO:0032048 cardiolipin metabolic process(GO:0032048)
0.7 6.1 GO:0070986 left/right axis specification(GO:0070986)
0.6 3.9 GO:0043137 DNA replication, removal of RNA primer(GO:0043137) positive regulation of sister chromatid cohesion(GO:0045876)
0.6 2.5 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.6 6.3 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.6 3.1 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.6 5.0 GO:0034770 histone H4-K20 methylation(GO:0034770)
0.6 5.2 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.6 1.7 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.6 2.3 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.6 5.1 GO:0071285 cellular response to lithium ion(GO:0071285)
0.6 4.5 GO:0016576 histone dephosphorylation(GO:0016576)
0.6 1.1 GO:2000564 CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
0.5 1.6 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.5 4.9 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.5 3.7 GO:0003433 chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.5 2.1 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.5 1.6 GO:0032829 regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829)
0.5 2.6 GO:0006868 glutamine transport(GO:0006868)
0.5 1.5 GO:0032430 positive regulation of phospholipase A2 activity(GO:0032430)
0.5 2.9 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.5 2.9 GO:0060903 positive regulation of meiosis I(GO:0060903)
0.5 3.8 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.5 2.3 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.5 12.0 GO:0046596 regulation of viral entry into host cell(GO:0046596)
0.5 5.1 GO:0070508 sterol import(GO:0035376) cholesterol import(GO:0070508)
0.5 1.4 GO:0045819 plasmacytoid dendritic cell activation(GO:0002270) positive regulation of glycogen catabolic process(GO:0045819)
0.4 2.2 GO:0002024 diet induced thermogenesis(GO:0002024)
0.4 1.3 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.4 1.7 GO:0015793 glycerol transport(GO:0015793)
0.4 0.8 GO:0072076 nephrogenic mesenchyme development(GO:0072076)
0.4 3.2 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.4 5.9 GO:1904293 negative regulation of ERAD pathway(GO:1904293)
0.4 1.6 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.4 1.5 GO:0045343 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343) positive regulation of MHC class I biosynthetic process(GO:0045345) positive regulation of NK T cell activation(GO:0051135)
0.4 1.5 GO:0055071 cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071)
0.4 1.1 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.4 2.6 GO:0016584 nucleosome positioning(GO:0016584)
0.4 0.7 GO:2000981 negative regulation of mechanoreceptor differentiation(GO:0045632) negative regulation of inner ear receptor cell differentiation(GO:2000981)
0.4 0.7 GO:0061738 late endosomal microautophagy(GO:0061738)
0.4 2.9 GO:0006004 fucose metabolic process(GO:0006004)
0.4 1.8 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.3 1.0 GO:0072092 ureteric bud invasion(GO:0072092) metanephric renal vesicle formation(GO:0072093)
0.3 3.8 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.3 1.0 GO:1904179 positive regulation of adipose tissue development(GO:1904179)
0.3 1.0 GO:0036233 glycine import(GO:0036233)
0.3 2.3 GO:0098535 de novo centriole assembly(GO:0098535)
0.3 1.0 GO:0021759 globus pallidus development(GO:0021759)
0.3 2.9 GO:0070423 nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431)
0.3 4.7 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.3 4.1 GO:0046643 regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643)
0.3 1.2 GO:0034239 regulation of macrophage fusion(GO:0034239)
0.3 0.9 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.3 2.1 GO:0007296 vitellogenesis(GO:0007296)
0.3 3.0 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.3 1.2 GO:0090527 actin filament reorganization(GO:0090527)
0.3 1.8 GO:0030913 paranodal junction assembly(GO:0030913)
0.3 3.6 GO:0021924 cell proliferation in external granule layer(GO:0021924) cerebellar granule cell precursor proliferation(GO:0021930)
0.3 1.1 GO:0006203 dGTP catabolic process(GO:0006203) dATP catabolic process(GO:0046061)
0.3 3.6 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.3 1.3 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.2 1.5 GO:1903847 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.2 1.2 GO:0003420 regulation of growth plate cartilage chondrocyte proliferation(GO:0003420)
0.2 0.2 GO:0032472 Golgi calcium ion transport(GO:0032472)
0.2 0.7 GO:0051026 chiasma assembly(GO:0051026)
0.2 2.1 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.2 1.4 GO:0061668 mitochondrial ribosome assembly(GO:0061668)
0.2 1.4 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.2 2.1 GO:1902913 positive regulation of melanocyte differentiation(GO:0045636) positive regulation of neuroepithelial cell differentiation(GO:1902913)
0.2 0.7 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
0.2 6.0 GO:0000132 establishment of mitotic spindle orientation(GO:0000132)
0.2 0.7 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.2 0.7 GO:1990927 negative regulation of tumor necrosis factor secretion(GO:1904468) negative regulation of membrane invagination(GO:1905154) calcium ion regulated lysosome exocytosis(GO:1990927)
0.2 9.9 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.2 1.7 GO:0010587 miRNA catabolic process(GO:0010587)
0.2 0.6 GO:0030070 insulin processing(GO:0030070)
0.2 1.4 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.2 0.6 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.2 2.9 GO:0050858 negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.2 0.6 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.2 0.9 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.2 3.5 GO:0098869 cellular oxidant detoxification(GO:0098869)
0.2 2.1 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.2 0.5 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.2 0.7 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.2 3.3 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.2 6.1 GO:0032611 interleukin-1 beta production(GO:0032611)
0.2 1.2 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.2 2.0 GO:0036120 cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.1 1.9 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.1 2.8 GO:0006825 copper ion transport(GO:0006825)
0.1 0.7 GO:1904659 glucose transmembrane transport(GO:1904659)
0.1 0.4 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.1 7.9 GO:0002066 columnar/cuboidal epithelial cell development(GO:0002066)
0.1 0.6 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.1 1.3 GO:0042989 sequestering of actin monomers(GO:0042989)
0.1 0.7 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.1 1.1 GO:0040016 embryonic cleavage(GO:0040016)
0.1 0.4 GO:0097278 transforming growth factor beta activation(GO:0036363) complement-dependent cytotoxicity(GO:0097278)
0.1 0.3 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.1 2.1 GO:0030813 positive regulation of nucleotide catabolic process(GO:0030813) positive regulation of glycolytic process(GO:0045821) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197)
0.1 0.6 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.1 3.3 GO:0006801 superoxide metabolic process(GO:0006801)
0.1 1.0 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.1 2.6 GO:0030575 nuclear body organization(GO:0030575)
0.1 4.8 GO:0070265 necrotic cell death(GO:0070265)
0.1 2.8 GO:0016180 snRNA processing(GO:0016180)
0.1 4.8 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 1.4 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.1 0.6 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.1 2.0 GO:0097062 dendritic spine maintenance(GO:0097062)
0.1 1.5 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.1 6.6 GO:0035019 somatic stem cell population maintenance(GO:0035019)
0.1 1.8 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1 1.9 GO:0031018 endocrine pancreas development(GO:0031018)
0.1 1.5 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.1 1.9 GO:0046621 negative regulation of organ growth(GO:0046621)
0.1 3.9 GO:0015914 phospholipid transport(GO:0015914)
0.1 4.1 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.1 2.6 GO:0010842 retina layer formation(GO:0010842)
0.1 1.2 GO:0042182 ketone catabolic process(GO:0042182)
0.1 1.9 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.1 0.1 GO:1905063 regulation of vascular smooth muscle cell differentiation(GO:1905063)
0.1 0.5 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.1 3.0 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.1 0.5 GO:0046349 amino sugar biosynthetic process(GO:0046349)
0.1 0.4 GO:0006741 NADP biosynthetic process(GO:0006741)
0.1 1.0 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.1 0.9 GO:0002227 innate immune response in mucosa(GO:0002227)
0.1 1.1 GO:0051451 myoblast migration(GO:0051451)
0.1 1.0 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.1 1.1 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.1 1.0 GO:0070914 UV-damage excision repair(GO:0070914)
0.1 0.6 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.1 2.1 GO:0007249 I-kappaB kinase/NF-kappaB signaling(GO:0007249)
0.1 1.1 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.1 0.6 GO:0060766 negative regulation of androgen receptor signaling pathway(GO:0060766)
0.1 0.2 GO:0002946 tRNA C5-cytosine methylation(GO:0002946)
0.1 2.2 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.1 0.7 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.1 1.5 GO:0045116 protein neddylation(GO:0045116)
0.1 1.1 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.1 0.5 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.1 0.7 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.1 4.2 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.1 0.5 GO:1901339 regulation of store-operated calcium channel activity(GO:1901339)
0.1 2.8 GO:0060612 adipose tissue development(GO:0060612)
0.1 2.9 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.1 4.9 GO:0009408 response to heat(GO:0009408)
0.1 0.6 GO:0045906 negative regulation of vasoconstriction(GO:0045906)
0.1 0.8 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.1 1.7 GO:0051642 centrosome localization(GO:0051642)
0.0 0.2 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 0.2 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.0 0.2 GO:0031282 regulation of guanylate cyclase activity(GO:0031282)
0.0 1.3 GO:0019915 lipid storage(GO:0019915)
0.0 0.1 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.2 GO:0046549 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 1.1 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.0 0.5 GO:0048311 mitochondrion distribution(GO:0048311)
0.0 0.4 GO:0045214 sarcomere organization(GO:0045214)
0.0 0.4 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.7 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.0 4.0 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0 0.3 GO:0060148 positive regulation of posttranscriptional gene silencing(GO:0060148)
0.0 0.3 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.3 GO:0019321 pentose metabolic process(GO:0019321)
0.0 0.4 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.0 0.7 GO:0045103 intermediate filament-based process(GO:0045103)
0.0 2.0 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 1.2 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 2.2 GO:0050772 positive regulation of axonogenesis(GO:0050772)
0.0 1.1 GO:0030500 regulation of bone mineralization(GO:0030500)
0.0 0.4 GO:0060351 cartilage development involved in endochondral bone morphogenesis(GO:0060351)
0.0 0.4 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.8 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.2 GO:0042474 middle ear morphogenesis(GO:0042474)
0.0 0.4 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.3 GO:0048636 positive regulation of striated muscle tissue development(GO:0045844) positive regulation of muscle organ development(GO:0048636) positive regulation of muscle tissue development(GO:1901863)
0.0 0.4 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.3 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.8 GO:0018022 peptidyl-lysine methylation(GO:0018022)
0.0 0.5 GO:0051057 positive regulation of small GTPase mediated signal transduction(GO:0051057)
0.0 0.2 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 17.1 GO:0097512 cardiac myofibril(GO:0097512)
2.3 9.3 GO:0071148 TEAD-1-YAP complex(GO:0071148)
2.0 15.8 GO:0005818 aster(GO:0005818)
1.9 5.8 GO:0042585 germinal vesicle(GO:0042585)
1.3 4.0 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
1.3 6.4 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
1.2 4.7 GO:0002111 BRCA2-BRAF35 complex(GO:0002111)
1.0 15.1 GO:0045180 basal cortex(GO:0045180)
1.0 5.0 GO:0033553 rDNA heterochromatin(GO:0033553)
0.8 4.9 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.8 2.4 GO:0005588 collagen type V trimer(GO:0005588)
0.7 7.9 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.6 11.0 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.5 1.5 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.5 2.5 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.5 1.4 GO:0099573 glutamatergic postsynaptic density(GO:0099573)
0.4 2.6 GO:0005677 chromatin silencing complex(GO:0005677)
0.4 6.0 GO:0030061 mitochondrial crista(GO:0030061)
0.4 2.3 GO:0098536 deuterosome(GO:0098536)
0.4 1.8 GO:0032389 MutLalpha complex(GO:0032389)
0.4 0.7 GO:0099524 region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524)
0.4 3.2 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.3 10.8 GO:0051233 spindle midzone(GO:0051233)
0.3 3.5 GO:0032591 dendritic spine membrane(GO:0032591)
0.3 1.6 GO:0031523 Myb complex(GO:0031523)
0.3 2.5 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.3 19.9 GO:0016459 myosin complex(GO:0016459)
0.3 8.0 GO:0005921 gap junction(GO:0005921)
0.3 3.5 GO:0061700 GATOR2 complex(GO:0061700)
0.3 1.9 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.3 6.3 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.2 3.3 GO:0097539 ciliary transition fiber(GO:0097539)
0.2 8.2 GO:0016235 aggresome(GO:0016235)
0.2 2.7 GO:0032593 insulin-responsive compartment(GO:0032593)
0.2 3.8 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.2 3.0 GO:0036038 MKS complex(GO:0036038)
0.2 1.3 GO:0042629 mast cell granule(GO:0042629)
0.2 10.0 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.2 2.8 GO:0032039 integrator complex(GO:0032039)
0.2 5.3 GO:0000788 nuclear nucleosome(GO:0000788)
0.2 10.6 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 2.5 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 0.9 GO:0045171 intercellular bridge(GO:0045171)
0.1 1.1 GO:0042382 paraspeckles(GO:0042382)
0.1 0.5 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1 1.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 1.7 GO:0031011 Ino80 complex(GO:0031011)
0.1 1.6 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 0.3 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.1 0.3 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.1 0.9 GO:0031595 nuclear proteasome complex(GO:0031595)
0.1 15.4 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.1 1.1 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1 2.8 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.1 1.1 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.1 3.9 GO:0002102 podosome(GO:0002102)
0.1 0.6 GO:0071203 WASH complex(GO:0071203)
0.1 0.5 GO:0042589 zymogen granule membrane(GO:0042589)
0.1 0.7 GO:0032009 early phagosome(GO:0032009)
0.1 4.6 GO:0005882 intermediate filament(GO:0005882)
0.1 5.7 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1 0.4 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 0.9 GO:0022627 small ribosomal subunit(GO:0015935) cytosolic small ribosomal subunit(GO:0022627)
0.1 5.7 GO:0005811 lipid particle(GO:0005811)
0.1 0.6 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.1 1.6 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1 1.0 GO:0042101 T cell receptor complex(GO:0042101)
0.1 2.3 GO:0031526 brush border membrane(GO:0031526)
0.1 2.2 GO:0034707 chloride channel complex(GO:0034707)
0.1 0.5 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 15.7 GO:0016607 nuclear speck(GO:0016607)
0.0 3.1 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.7 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 1.7 GO:0044295 axonal growth cone(GO:0044295)
0.0 1.7 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 2.5 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 1.1 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.3 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.7 GO:0001741 XY body(GO:0001741)
0.0 0.6 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.2 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 1.3 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 2.4 GO:0000502 proteasome complex(GO:0000502)
0.0 0.9 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 0.5 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 3.7 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 1.3 GO:0005911 cell-cell junction(GO:0005911)
0.0 0.7 GO:0000795 synaptonemal complex(GO:0000795)
0.0 1.6 GO:0005776 autophagosome(GO:0005776)
0.0 1.2 GO:0030315 T-tubule(GO:0030315)
0.0 1.0 GO:0005871 kinesin complex(GO:0005871)
0.0 4.4 GO:0005802 trans-Golgi network(GO:0005802)
0.0 1.6 GO:0005814 centriole(GO:0005814)
0.0 1.3 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.2 GO:0034518 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 2.0 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.0 1.5 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.4 GO:0043034 costamere(GO:0043034)
0.0 1.1 GO:0016605 PML body(GO:0016605)
0.0 0.8 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.6 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.0 2.5 GO:0031965 nuclear membrane(GO:0031965)
0.0 2.2 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.0 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.1 GO:0055037 recycling endosome(GO:0055037)
0.0 1.1 GO:0043296 apical junction complex(GO:0043296)
0.0 0.1 GO:0030126 COPI vesicle coat(GO:0030126)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.4 10.3 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
2.6 10.5 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
2.5 7.5 GO:0005110 frizzled-2 binding(GO:0005110)
1.8 15.8 GO:0061676 importin-alpha family protein binding(GO:0061676)
1.7 5.1 GO:0032052 bile acid binding(GO:0032052)
1.6 4.9 GO:0004774 succinate-CoA ligase activity(GO:0004774)
1.4 5.7 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
1.4 4.2 GO:0005118 sevenless binding(GO:0005118)
1.3 7.6 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
1.3 16.3 GO:0038191 neuropilin binding(GO:0038191)
1.2 9.6 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
1.2 4.8 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
1.2 4.8 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
1.2 3.5 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038) protein-disulfide reductase (glutathione) activity(GO:0019153)
1.2 5.8 GO:0035174 histone serine kinase activity(GO:0035174)
1.1 5.3 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
1.0 3.1 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
1.0 21.6 GO:0070410 co-SMAD binding(GO:0070410)
0.9 5.3 GO:0070644 vitamin D response element binding(GO:0070644)
0.8 3.3 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.8 2.4 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.8 7.3 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.8 3.9 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.7 2.9 GO:0042806 fucose binding(GO:0042806)
0.7 2.8 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.7 4.0 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.6 1.7 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.6 2.8 GO:0032767 copper-dependent protein binding(GO:0032767)
0.5 5.5 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.5 4.6 GO:0001972 retinoic acid binding(GO:0001972)
0.5 3.1 GO:0070728 leucine binding(GO:0070728)
0.5 5.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.5 2.0 GO:0008802 betaine-aldehyde dehydrogenase activity(GO:0008802)
0.5 2.9 GO:0030284 estrogen receptor activity(GO:0030284)
0.5 9.3 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.5 5.7 GO:0070097 delta-catenin binding(GO:0070097)
0.5 1.4 GO:0000402 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
0.5 5.0 GO:0001163 RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.4 3.0 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.4 1.3 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.4 2.1 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.4 1.2 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.4 1.7 GO:0015254 glycerol channel activity(GO:0015254)
0.4 1.6 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.4 1.6 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.4 1.5 GO:0015410 manganese-transporting ATPase activity(GO:0015410)
0.4 7.2 GO:0035497 cAMP response element binding(GO:0035497)
0.4 3.0 GO:0031432 titin binding(GO:0031432)
0.4 1.8 GO:0000405 bubble DNA binding(GO:0000405)
0.4 4.6 GO:0030957 Tat protein binding(GO:0030957)
0.4 14.2 GO:0030291 protein serine/threonine kinase inhibitor activity(GO:0030291)
0.3 5.2 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.3 1.4 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.3 10.8 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.3 1.7 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.3 2.6 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.3 1.0 GO:0042288 MHC class I protein binding(GO:0042288)
0.3 16.9 GO:0001784 phosphotyrosine binding(GO:0001784)
0.3 1.9 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.3 0.6 GO:0061665 SUMO ligase activity(GO:0061665)
0.3 3.2 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.3 1.1 GO:0045322 unmethylated CpG binding(GO:0045322)
0.3 12.6 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.3 3.0 GO:0017147 Wnt-protein binding(GO:0017147)
0.3 2.4 GO:0043237 laminin-1 binding(GO:0043237)
0.3 1.1 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.3 4.7 GO:0000400 four-way junction DNA binding(GO:0000400)
0.3 3.3 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.3 1.5 GO:0042731 PH domain binding(GO:0042731)
0.2 1.5 GO:0016018 cyclosporin A binding(GO:0016018)
0.2 4.4 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.2 3.6 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.2 4.2 GO:0005540 hyaluronic acid binding(GO:0005540)
0.2 0.7 GO:0071633 dihydroceramidase activity(GO:0071633)
0.2 2.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.2 0.7 GO:0071723 lipopeptide binding(GO:0071723)
0.2 2.8 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.2 6.4 GO:0008307 structural constituent of muscle(GO:0008307)
0.2 0.8 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.2 6.6 GO:0005112 Notch binding(GO:0005112)
0.2 1.1 GO:0001069 regulatory region RNA binding(GO:0001069)
0.2 5.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.2 6.3 GO:0032452 histone demethylase activity(GO:0032452)
0.2 3.9 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.2 1.2 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.2 1.7 GO:0001055 RNA polymerase II activity(GO:0001055)
0.2 1.5 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.2 1.0 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.2 1.0 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.2 1.8 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.2 2.5 GO:0001056 RNA polymerase III activity(GO:0001056)
0.2 1.2 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.2 2.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.2 5.4 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 1.0 GO:1901612 phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612)
0.1 2.0 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.1 0.6 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.1 1.5 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 4.6 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 2.3 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 0.7 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.1 0.9 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 5.2 GO:0005504 fatty acid binding(GO:0005504)
0.1 0.5 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.1 0.9 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.1 5.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 0.7 GO:0030983 mismatched DNA binding(GO:0030983)
0.1 0.7 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.1 0.9 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 5.3 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 0.6 GO:0043532 angiostatin binding(GO:0043532)
0.1 1.4 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931) calcium-dependent protein kinase activity(GO:0010857)
0.1 0.5 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.1 0.7 GO:0034452 dynactin binding(GO:0034452)
0.1 1.5 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1 6.6 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.1 2.6 GO:0051879 Hsp90 protein binding(GO:0051879)
0.1 1.0 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.1 4.1 GO:0070888 E-box binding(GO:0070888)
0.1 8.9 GO:0003774 motor activity(GO:0003774)
0.1 1.0 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 0.6 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 0.8 GO:0008301 DNA binding, bending(GO:0008301)
0.1 2.1 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 1.0 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.1 0.4 GO:0003951 NAD+ kinase activity(GO:0003951)
0.1 3.3 GO:0051018 protein kinase A binding(GO:0051018)
0.1 1.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 0.5 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 0.2 GO:0052740 phosphatidylserine 1-acylhydrolase activity(GO:0052739) 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.1 1.3 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 0.2 GO:0030249 guanylate cyclase regulator activity(GO:0030249)
0.1 0.4 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.1 8.3 GO:0008201 heparin binding(GO:0008201)
0.1 1.1 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 0.7 GO:0008430 selenium binding(GO:0008430)
0.1 0.3 GO:0070883 pre-miRNA binding(GO:0070883)
0.1 1.0 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.1 0.5 GO:0046790 virion binding(GO:0046790)
0.1 5.6 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.1 0.6 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.1 1.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 0.6 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.1 1.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.7 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.0 1.1 GO:0070064 proline-rich region binding(GO:0070064)
0.0 1.3 GO:0003785 actin monomer binding(GO:0003785)
0.0 2.6 GO:0030295 protein kinase activator activity(GO:0030295)
0.0 1.6 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.5 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.0 1.1 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 2.5 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 4.1 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.1 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.0 2.2 GO:0005254 chloride channel activity(GO:0005254)
0.0 1.1 GO:0005109 frizzled binding(GO:0005109)
0.0 0.3 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 1.5 GO:0016278 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.0 7.1 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 1.6 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.5 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 1.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 1.2 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.7 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 1.3 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.2 GO:0042301 phosphate ion binding(GO:0042301)
0.0 0.4 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.1 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.0 0.3 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 2.0 GO:0005178 integrin binding(GO:0005178)
0.0 1.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.2 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.0 0.6 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 1.9 GO:0005125 cytokine activity(GO:0005125)
0.0 0.7 GO:0001221 transcription cofactor binding(GO:0001221)
0.0 0.2 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.4 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 6.2 GO:0045296 cadherin binding(GO:0045296)
0.0 1.1 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 1.0 GO:0017022 myosin binding(GO:0017022)
0.0 0.6 GO:0004601 peroxidase activity(GO:0004601)
0.0 0.2 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.7 GO:0003682 chromatin binding(GO:0003682)
0.0 0.6 GO:0005179 hormone activity(GO:0005179)
0.0 0.7 GO:0004004 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 22.4 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.5 21.8 PID_AURORA_A_PATHWAY Aurora A signaling
0.4 7.8 ST_STAT3_PATHWAY STAT3 Pathway
0.4 1.2 ST_INTERFERON_GAMMA_PATHWAY Interferon gamma pathway.
0.4 13.5 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.4 10.5 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.3 12.2 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.3 5.8 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.3 9.7 PID_IGF1_PATHWAY IGF1 pathway
0.3 11.1 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.3 11.0 PID_PS1_PATHWAY Presenilin action in Notch and Wnt signaling
0.3 25.0 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.3 7.5 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.2 4.5 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.2 2.5 PID_PI3KCI_PATHWAY Class I PI3K signaling events
0.2 3.6 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.2 3.6 PID_PRL_SIGNALING_EVENTS_PATHWAY Signaling events mediated by PRL
0.2 6.8 PID_ATM_PATHWAY ATM pathway
0.2 2.8 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.2 2.7 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 17.7 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 2.0 PID_VEGFR1_2_PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.1 2.1 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.1 3.0 PID_IL1_PATHWAY IL1-mediated signaling events
0.1 5.1 PID_THROMBIN_PAR1_PATHWAY PAR1-mediated thrombin signaling events
0.1 3.8 PID_REELIN_PATHWAY Reelin signaling pathway
0.1 1.6 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway
0.1 1.8 PID_A6B1_A6B4_INTEGRIN_PATHWAY a6b1 and a6b4 Integrin signaling
0.1 3.6 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events
0.1 2.7 PID_ARF6_PATHWAY Arf6 signaling events
0.1 1.4 PID_AMB2_NEUTROPHILS_PATHWAY amb2 Integrin signaling
0.1 1.9 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.1 3.3 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.1 0.6 PID_RANBP2_PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 1.0 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.1 1.1 PID_IFNG_PATHWAY IFN-gamma pathway
0.1 2.8 PID_PLK1_PATHWAY PLK1 signaling events
0.1 5.1 PID_ERBB1_DOWNSTREAM_PATHWAY ErbB1 downstream signaling
0.0 1.9 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.3 ST_DIFFERENTIATION_PATHWAY_IN_PC12_CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 1.3 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.4 PID_IL27_PATHWAY IL27-mediated signaling events
0.0 0.4 PID_CONE_PATHWAY Visual signal transduction: Cones
0.0 1.8 ST_FAS_SIGNALING_PATHWAY Fas Signaling Pathway
0.0 1.9 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.0 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.8 PID_NOTCH_PATHWAY Notch signaling pathway
0.0 2.3 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.4 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.1 PID_IL6_7_PATHWAY IL6-mediated signaling events
0.0 0.7 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 10.3 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.7 9.0 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.6 22.6 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.6 6.1 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.5 18.7 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.5 9.7 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.4 13.3 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.4 3.9 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.4 5.1 REACTOME_STEROID_HORMONES Genes involved in Steroid hormones
0.4 2.5 REACTOME_REPAIR_SYNTHESIS_FOR_GAP_FILLING_BY_DNA_POL_IN_TC_NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.4 21.8 REACTOME_DESTABILIZATION_OF_MRNA_BY_AUF1_HNRNP_D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.4 2.8 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION_IN_TLR7_8_OR_9_SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.3 7.8 REACTOME_PYRUVATE_METABOLISM Genes involved in Pyruvate metabolism
0.3 9.3 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.3 6.9 REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.3 5.8 REACTOME_APC_C_CDH1_MEDIATED_DEGRADATION_OF_CDC20_AND_OTHER_APC_C_CDH1_TARGETED_PROTEINS_IN_LATE_MITOSIS_EARLY_G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.3 5.9 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.2 4.9 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.2 1.5 REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE_ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.2 0.6 REACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.2 2.5 REACTOME_PECAM1_INTERACTIONS Genes involved in PECAM1 interactions
0.1 1.6 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.1 1.7 REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 8.2 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.1 2.3 REACTOME_DESTABILIZATION_OF_MRNA_BY_TRISTETRAPROLIN_TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.1 2.5 REACTOME_RNA_POL_III_CHAIN_ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.1 4.2 REACTOME_PPARA_ACTIVATES_GENE_EXPRESSION Genes involved in PPARA Activates Gene Expression
0.1 1.1 REACTOME_P53_DEPENDENT_G1_DNA_DAMAGE_RESPONSE Genes involved in p53-Dependent G1 DNA Damage Response
0.1 1.4 REACTOME_ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 7.8 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.1 2.7 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.1 2.2 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.1 0.4 REACTOME_THE_NLRP3_INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 2.5 REACTOME_INTERFERON_GAMMA_SIGNALING Genes involved in Interferon gamma signaling
0.1 0.5 REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 4.1 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 0.9 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.1 1.9 REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT Genes involved in Regulation of beta-cell development
0.1 3.1 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 1.2 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 2.0 REACTOME_MRNA_3_END_PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.7 REACTOME_MEIOTIC_RECOMBINATION Genes involved in Meiotic Recombination
0.0 1.5 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.6 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 5.6 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.7 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 3.1 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 1.9 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.8 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.5 REACTOME_PEROXISOMAL_LIPID_METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.1 REACTOME_IRAK1_RECRUITS_IKK_COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.3 REACTOME_RNA_POL_I_TRANSCRIPTION Genes involved in RNA Polymerase I Transcription