Motif ID: Hsf4

Z-value: 0.677


Transcription factors associated with Hsf4:

Gene SymbolEntrez IDGene Name
Hsf4 ENSMUSG00000033249.4 Hsf4



Activity profile for motif Hsf4.

activity profile for motif Hsf4


Sorted Z-values histogram for motif Hsf4

Sorted Z-values for motif Hsf4



Network of associatons between targets according to the STRING database.



First level regulatory network of Hsf4

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_-_66801577 5.932 ENSMUST00000168589.1
Sla
src-like adaptor
chr12_-_110696289 3.799 ENSMUST00000021698.6
Hsp90aa1
heat shock protein 90, alpha (cytosolic), class A member 1
chr9_+_71215779 3.371 ENSMUST00000034723.5
Aldh1a2
aldehyde dehydrogenase family 1, subfamily A2
chr4_-_136892867 3.044 ENSMUST00000046332.5
C1qc
complement component 1, q subcomponent, C chain
chr12_-_110696248 2.910 ENSMUST00000124156.1
Hsp90aa1
heat shock protein 90, alpha (cytosolic), class A member 1
chr12_-_110696332 2.900 ENSMUST00000094361.4
Hsp90aa1
heat shock protein 90, alpha (cytosolic), class A member 1
chr12_-_70111920 2.879 ENSMUST00000169074.1
ENSMUST00000021468.7
Nin

ninein

chr8_-_71537402 2.761 ENSMUST00000051672.7
Bst2
bone marrow stromal cell antigen 2
chr1_+_194938821 2.610 ENSMUST00000016638.2
ENSMUST00000110815.2
Cd34

CD34 antigen

chr7_-_110862944 2.572 ENSMUST00000033050.3
Lyve1
lymphatic vessel endothelial hyaluronan receptor 1
chr4_-_46566432 2.527 ENSMUST00000030021.7
ENSMUST00000107757.1
Coro2a

coronin, actin binding protein 2A

chr12_-_110695860 2.504 ENSMUST00000149189.1
Hsp90aa1
heat shock protein 90, alpha (cytosolic), class A member 1
chr12_+_75308308 2.436 ENSMUST00000118602.1
ENSMUST00000118966.1
ENSMUST00000055390.5
Rhoj


ras homolog gene family, member J


chr1_+_195017399 2.410 ENSMUST00000181273.1
A330023F24Rik
RIKEN cDNA A330023F24 gene
chr2_+_130405256 2.151 ENSMUST00000110281.1
ENSMUST00000028898.3
1700020A23Rik

RIKEN cDNA 1700020A23 gene

chr7_+_49246131 2.115 ENSMUST00000064395.6
Nav2
neuron navigator 2
chr9_-_13827029 2.069 ENSMUST00000148086.1
ENSMUST00000034398.5
Cep57

centrosomal protein 57

chr9_+_13827708 2.012 ENSMUST00000059579.5
Fam76b
family with sequence similarity 76, member B
chr10_-_62507737 1.993 ENSMUST00000020271.6
Srgn
serglycin
chr13_-_111490111 1.910 ENSMUST00000047627.7
Gpbp1
GC-rich promoter binding protein 1
chr13_-_62607499 1.883 ENSMUST00000091563.4
6720489N17Rik
RIKEN cDNA 6720489N17 gene
chr10_-_80844025 1.741 ENSMUST00000053986.7
Lingo3
leucine rich repeat and Ig domain containing 3
chr15_+_82252397 1.730 ENSMUST00000136948.1
1500009C09Rik
RIKEN cDNA 1500009C09 gene
chr5_-_123749393 1.724 ENSMUST00000057795.5
ENSMUST00000111515.1
ENSMUST00000182309.1
Rsrc2


arginine/serine-rich coiled-coil 2


chr5_-_123749371 1.711 ENSMUST00000182955.1
ENSMUST00000182489.1
ENSMUST00000050827.7
Rsrc2


arginine/serine-rich coiled-coil 2


chr17_+_17316078 1.690 ENSMUST00000105311.3
Gm6712
predicted gene 6712
chr1_+_59684949 1.679 ENSMUST00000027174.3
Nop58
NOP58 ribonucleoprotein
chr17_+_35424842 1.576 ENSMUST00000174699.1
H2-Q6
histocompatibility 2, Q region locus 6
chr7_-_46179929 1.561 ENSMUST00000033123.6
Abcc8
ATP-binding cassette, sub-family C (CFTR/MRP), member 8
chr9_-_13826946 1.555 ENSMUST00000147115.1
Cep57
centrosomal protein 57
chr18_+_66458587 1.487 ENSMUST00000025399.7
Pmaip1
phorbol-12-myristate-13-acetate-induced protein 1
chr13_+_81657732 1.448 ENSMUST00000049055.6
Lysmd3
LysM, putative peptidoglycan-binding, domain containing 3
chr17_+_17831004 1.443 ENSMUST00000172097.2
4930546H06Rik
RIKEN cDNA 4930546H06 gene
chr2_-_64975762 1.398 ENSMUST00000156765.1
Grb14
growth factor receptor bound protein 14
chr13_-_111490028 1.368 ENSMUST00000091236.4
Gpbp1
GC-rich promoter binding protein 1
chr14_+_34375504 1.354 ENSMUST00000111908.1
Mmrn2
multimerin 2
chr16_-_52452654 1.340 ENSMUST00000168071.1
Alcam
activated leukocyte cell adhesion molecule
chr16_+_23107413 1.334 ENSMUST00000023599.6
ENSMUST00000168891.1
Eif4a2

eukaryotic translation initiation factor 4A2

chr3_+_30792876 1.324 ENSMUST00000029256.7
Sec62
SEC62 homolog (S. cerevisiae)
chr3_+_79591356 1.312 ENSMUST00000029382.7
Ppid
peptidylprolyl isomerase D (cyclophilin D)
chr6_-_136941887 1.299 ENSMUST00000111891.1
Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
chr17_+_21491256 1.298 ENSMUST00000076664.6
Zfp53
zinc finger protein 53
chr18_+_37504264 1.284 ENSMUST00000052179.6
Pcdhb20
protocadherin beta 20
chrX_+_101640056 1.273 ENSMUST00000119299.1
ENSMUST00000044475.4
Ogt

O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)

chr10_-_86705485 1.269 ENSMUST00000020238.7
Hsp90b1
heat shock protein 90, beta (Grp94), member 1
chr4_+_127077374 1.254 ENSMUST00000046751.6
ENSMUST00000094713.3
Zmym6

zinc finger, MYM-type 6

chr15_-_99528017 1.253 ENSMUST00000023750.7
Faim2
Fas apoptotic inhibitory molecule 2
chr19_+_47854970 1.202 ENSMUST00000026050.7
Gsto1
glutathione S-transferase omega 1
chr11_-_110168073 1.188 ENSMUST00000044850.3
Abca9
ATP-binding cassette, sub-family A (ABC1), member 9
chr17_+_3532554 1.186 ENSMUST00000168560.1
Cldn20
claudin 20
chr11_-_59163281 1.186 ENSMUST00000069631.2
Iba57
IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
chr3_+_68468162 1.159 ENSMUST00000182532.1
Schip1
schwannomin interacting protein 1
chr17_+_21707682 1.137 ENSMUST00000073312.6
Zfp760
zinc finger protein 760
chr19_+_26748268 1.137 ENSMUST00000175791.1
ENSMUST00000176698.1
ENSMUST00000177252.1
ENSMUST00000176475.1
ENSMUST00000112637.2
Smarca2




SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2




chr6_-_59024470 1.135 ENSMUST00000089860.5
Fam13a
family with sequence similarity 13, member A
chr17_+_35236556 1.129 ENSMUST00000068261.8
Atp6v1g2
ATPase, H+ transporting, lysosomal V1 subunit G2
chr9_+_50752758 1.124 ENSMUST00000034562.7
Cryab
crystallin, alpha B
chr2_-_146511992 1.124 ENSMUST00000109986.2
Ralgapa2
Ral GTPase activating protein, alpha subunit 2 (catalytic)
chr13_+_42866247 1.110 ENSMUST00000131942.1
Phactr1
phosphatase and actin regulator 1
chr2_+_119897212 1.105 ENSMUST00000046717.6
ENSMUST00000110774.1
ENSMUST00000110773.2
ENSMUST00000079934.5
ENSMUST00000156510.1
Mga




MAX gene associated




chr17_-_34972124 1.101 ENSMUST00000087328.2
ENSMUST00000179128.1
Hspa1a

heat shock protein 1A

chr1_-_55088024 1.098 ENSMUST00000027123.8
Hspd1
heat shock protein 1 (chaperonin)
chr17_+_3326552 1.043 ENSMUST00000169838.1
Tiam2
T cell lymphoma invasion and metastasis 2
chr18_-_70472429 1.040 ENSMUST00000067556.3
4930503L19Rik
RIKEN cDNA 4930503L19 gene
chr19_-_5845471 1.024 ENSMUST00000174287.1
ENSMUST00000173672.1
Neat1

nuclear paraspeckle assembly transcript 1 (non-protein coding)

chr16_+_23107754 0.999 ENSMUST00000077605.5
ENSMUST00000115341.3
Eif4a2

eukaryotic translation initiation factor 4A2

chr10_-_100589205 0.991 ENSMUST00000054471.8
4930430F08Rik
RIKEN cDNA 4930430F08 gene
chr6_-_54972603 0.984 ENSMUST00000060655.8
Nod1
nucleotide-binding oligomerization domain containing 1
chr4_-_40722307 0.977 ENSMUST00000181475.1
Gm6297
predicted gene 6297
chr11_-_54860564 0.970 ENSMUST00000144164.1
Lyrm7
LYR motif containing 7
chr13_-_52530827 0.970 ENSMUST00000057442.6
Diras2
DIRAS family, GTP-binding RAS-like 2
chrX_+_42149288 0.965 ENSMUST00000115073.2
ENSMUST00000115072.1
Stag2

stromal antigen 2

chrX_-_139871637 0.949 ENSMUST00000033811.7
ENSMUST00000087401.5
Morc4

microrchidia 4

chr16_-_20426322 0.942 ENSMUST00000115547.2
ENSMUST00000096199.4
Abcc5

ATP-binding cassette, sub-family C (CFTR/MRP), member 5

chrX_+_73214333 0.941 ENSMUST00000156188.1
ENSMUST00000069077.3
ENSMUST00000069103.4
ENSMUST00000114506.1
ENSMUST00000081827.3
Xlr4b




X-linked lymphocyte-regulated 4B




chr7_-_126949499 0.939 ENSMUST00000106339.1
ENSMUST00000052937.5
Asphd1

aspartate beta-hydroxylase domain containing 1

chr3_-_36475688 0.912 ENSMUST00000029266.8
Anxa5
annexin A5
chr3_-_113630068 0.903 ENSMUST00000092154.3
ENSMUST00000106536.1
ENSMUST00000106535.1
Rnpc3


RNA-binding region (RNP1, RRM) containing 3


chrX_-_109013389 0.902 ENSMUST00000033597.8
Hmgn5
high-mobility group nucleosome binding domain 5
chr6_-_136941494 0.899 ENSMUST00000111892.1
Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
chr16_+_91225550 0.894 ENSMUST00000035608.8
Olig2
oligodendrocyte transcription factor 2
chr3_+_81036360 0.890 ENSMUST00000029652.3
Pdgfc
platelet-derived growth factor, C polypeptide
chr10_+_100488289 0.885 ENSMUST00000164751.1
Cep290
centrosomal protein 290
chr6_-_136941694 0.871 ENSMUST00000032344.5
Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
chrY_-_90754821 0.869 ENSMUST00000177893.1
Gm21860
predicted gene, 21860
chr5_-_3596540 0.862 ENSMUST00000042753.7
Rbm48
RNA binding motif protein 48
chr19_-_44069526 0.857 ENSMUST00000170801.1
Erlin1
ER lipid raft associated 1
chr1_-_33757711 0.847 ENSMUST00000044691.7
Bag2
BCL2-associated athanogene 2
chr1_+_42953106 0.835 ENSMUST00000179655.1
Gpr45
G protein-coupled receptor 45
chrY_-_90839177 0.826 ENSMUST00000179623.1
Gm21748
predicted gene, 21748
chr11_+_97415527 0.825 ENSMUST00000121799.1
Arhgap23
Rho GTPase activating protein 23
chr11_+_70130329 0.825 ENSMUST00000041550.5
ENSMUST00000165951.1
Mgl2

macrophage galactose N-acetyl-galactosamine specific lectin 2

chr4_+_17853451 0.821 ENSMUST00000029881.3
Mmp16
matrix metallopeptidase 16
chr1_-_55088156 0.814 ENSMUST00000127861.1
ENSMUST00000144077.1
Hspd1

heat shock protein 1 (chaperonin)

chr13_+_75967704 0.813 ENSMUST00000022081.1
Spata9
spermatogenesis associated 9
chr12_-_72236692 0.813 ENSMUST00000021497.9
ENSMUST00000137990.1
Rtn1

reticulon 1

chr17_+_34135182 0.784 ENSMUST00000042121.9
H2-DMa
histocompatibility 2, class II, locus DMa
chr1_-_126830632 0.776 ENSMUST00000112583.1
ENSMUST00000094609.3
Nckap5

NCK-associated protein 5

chr14_-_79390666 0.759 ENSMUST00000022597.7
Naa16
N(alpha)-acetyltransferase 16, NatA auxiliary subunit
chr16_+_19760232 0.756 ENSMUST00000079780.3
ENSMUST00000164397.1
B3gnt5

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5

chr6_+_51470339 0.753 ENSMUST00000094623.3
Cbx3
chromobox 3
chr6_-_59024340 0.750 ENSMUST00000173193.1
Fam13a
family with sequence similarity 13, member A
chr17_+_35470083 0.744 ENSMUST00000174525.1
ENSMUST00000068291.6
H2-Q10

histocompatibility 2, Q region locus 10

chr19_-_44069690 0.738 ENSMUST00000169092.1
Erlin1
ER lipid raft associated 1
chr2_-_7081256 0.733 ENSMUST00000183209.1
Celf2
CUGBP, Elav-like family member 2
chr19_-_29812952 0.732 ENSMUST00000099525.3
Ranbp6
RAN binding protein 6
chr17_+_53479212 0.722 ENSMUST00000017975.5
Rab5a
RAB5A, member RAS oncogene family
chr5_+_92331828 0.711 ENSMUST00000125462.1
ENSMUST00000121096.1
ENSMUST00000113083.2
Art3


ADP-ribosyltransferase 3


chr2_+_29124106 0.707 ENSMUST00000129544.1
Setx
senataxin
chr8_-_48555846 0.701 ENSMUST00000110345.1
ENSMUST00000110343.1
Tenm3

teneurin transmembrane protein 3

chr17_+_35424870 0.701 ENSMUST00000113879.3
H2-Q6
histocompatibility 2, Q region locus 6
chr8_+_71887264 0.697 ENSMUST00000034259.7
Zfp709
zinc finger protein 709
chr7_-_122067263 0.696 ENSMUST00000033159.3
Ears2
glutamyl-tRNA synthetase 2 (mitochondrial)(putative)
chr13_+_105443693 0.696 ENSMUST00000022235.4
Htr1a
5-hydroxytryptamine (serotonin) receptor 1A
chr11_+_82045705 0.694 ENSMUST00000021011.2
Ccl7
chemokine (C-C motif) ligand 7
chr2_+_19344820 0.689 ENSMUST00000150514.1
ENSMUST00000136456.1
4930447M23Rik

RIKEN cDNA 4930447M23 gene

chr3_+_67892189 0.688 ENSMUST00000063263.3
Iqcj
IQ motif containing J
chr10_+_29313500 0.687 ENSMUST00000020034.4
Echdc1
enoyl Coenzyme A hydratase domain containing 1
chr9_+_58582240 0.686 ENSMUST00000177292.1
ENSMUST00000085651.5
Nptn

neuroplastin

chr11_+_116657106 0.683 ENSMUST00000116318.2
Gm11744
predicted gene 11744
chr6_+_86527312 0.681 ENSMUST00000181928.1
1600020E01Rik
RIKEN cDNA 1600020E01 gene
chr11_+_17159263 0.673 ENSMUST00000102880.4
Ppp3r1
protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I)
chr11_+_49609263 0.673 ENSMUST00000020617.2
Flt4
FMS-like tyrosine kinase 4
chr16_-_20426375 0.672 ENSMUST00000079158.6
Abcc5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chrX_-_61185558 0.671 ENSMUST00000166381.1
Cdr1
cerebellar degeneration related antigen 1
chr4_-_49593875 0.670 ENSMUST00000151542.1
Tmem246
transmembrane protein 246
chr16_+_19760195 0.670 ENSMUST00000121344.1
B3gnt5
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
chr5_-_92675253 0.663 ENSMUST00000151180.1
ENSMUST00000150359.1
Ccdc158

coiled-coil domain containing 158

chr5_+_135887905 0.662 ENSMUST00000005077.6
Hspb1
heat shock protein 1
chr10_-_120979327 0.657 ENSMUST00000119944.1
ENSMUST00000119093.1
Lemd3

LEM domain containing 3

chr12_-_72408934 0.649 ENSMUST00000078505.7
Rtn1
reticulon 1
chr2_-_168230353 0.647 ENSMUST00000154111.1
Dpm1
dolichol-phosphate (beta-D) mannosyltransferase 1
chr6_-_121003099 0.646 ENSMUST00000098457.2
ENSMUST00000150503.1
Mical3

microtubule associated monooxygenase, calponin and LIM domain containing 3

chr19_-_60790692 0.642 ENSMUST00000025955.6
Eif3a
eukaryotic translation initiation factor 3, subunit A
chr2_-_39065505 0.640 ENSMUST00000039165.8
Golga1
golgi autoantigen, golgin subfamily a, 1
chr19_-_5366626 0.638 ENSMUST00000025762.8
Banf1
barrier to autointegration factor 1
chr5_+_135887988 0.637 ENSMUST00000111155.1
Hspb1
heat shock protein 1
chr4_+_152178126 0.629 ENSMUST00000075363.3
Acot7
acyl-CoA thioesterase 7
chr9_+_112227443 0.622 ENSMUST00000161216.1
2310075C17Rik
RIKEN cDNA 2310075C17 gene
chr1_+_42952872 0.615 ENSMUST00000179766.1
Gpr45
G protein-coupled receptor 45
chr6_+_48647224 0.609 ENSMUST00000078223.3
Gimap8
GTPase, IMAP family member 8
chr1_-_52817643 0.602 ENSMUST00000027271.2
Inpp1
inositol polyphosphate-1-phosphatase
chr17_-_45592569 0.589 ENSMUST00000163492.1
Slc29a1
solute carrier family 29 (nucleoside transporters), member 1
chr11_+_82911253 0.588 ENSMUST00000164945.1
ENSMUST00000018989.7
Unc45b

unc-45 homolog B (C. elegans)

chr6_+_142345648 0.577 ENSMUST00000041852.7
Pyroxd1
pyridine nucleotide-disulphide oxidoreductase domain 1
chr1_+_57774600 0.570 ENSMUST00000167971.1
ENSMUST00000170139.1
ENSMUST00000171699.1
ENSMUST00000164302.1
Spats2l



spermatogenesis associated, serine-rich 2-like



chr2_+_120567652 0.568 ENSMUST00000110711.2
Snap23
synaptosomal-associated protein 23
chr2_-_175133322 0.568 ENSMUST00000099029.3
Gm14399
predicted gene 14399
chrX_-_150657392 0.566 ENSMUST00000151403.2
ENSMUST00000087253.4
ENSMUST00000112709.1
ENSMUST00000163969.1
ENSMUST00000087258.3
Tro




trophinin




chr2_-_39065438 0.553 ENSMUST00000112850.2
Golga1
golgi autoantigen, golgin subfamily a, 1
chr9_+_22411515 0.551 ENSMUST00000058868.7
9530077C05Rik
RIKEN cDNA 9530077C05 gene
chr9_+_58582397 0.551 ENSMUST00000176557.1
ENSMUST00000114121.4
ENSMUST00000177064.1
Nptn


neuroplastin


chr5_+_29735940 0.544 ENSMUST00000114839.1
Dnajb6
DnaJ (Hsp40) homolog, subfamily B, member 6
chr2_-_168230575 0.541 ENSMUST00000109193.1
Dpm1
dolichol-phosphate (beta-D) mannosyltransferase 1
chr7_+_24399606 0.536 ENSMUST00000002280.4
Smg9
smg-9 homolog, nonsense mediated mRNA decay factor (C. elegans)
chr11_-_26210553 0.536 ENSMUST00000101447.3
5730522E02Rik
RIKEN cDNA 5730522E02 gene
chr18_+_53176345 0.535 ENSMUST00000037850.5
Snx2
sorting nexin 2
chr12_-_116262946 0.534 ENSMUST00000039349.6
Wdr60
WD repeat domain 60
chr5_-_23783700 0.531 ENSMUST00000119946.1
Pus7
pseudouridylate synthase 7 homolog (S. cerevisiae)
chr1_+_55088132 0.528 ENSMUST00000075242.6
Hspe1
heat shock protein 1 (chaperonin 10)
chr11_-_101987004 0.523 ENSMUST00000107173.2
ENSMUST00000107172.1
Dusp3

dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related)

chr17_+_35262730 0.523 ENSMUST00000172785.1
H2-D1
histocompatibility 2, D region locus 1
chr3_-_89402650 0.519 ENSMUST00000168325.1
ENSMUST00000057431.5
Lenep

lens epithelial protein

chr11_+_21239279 0.509 ENSMUST00000006221.7
ENSMUST00000109578.1
Vps54

vacuolar protein sorting 54 (yeast)

chr14_+_3449379 0.498 ENSMUST00000096168.5
Gm10408
predicted gene 10408
chr5_-_139484475 0.494 ENSMUST00000110851.1
ENSMUST00000079996.6
Zfand2a

zinc finger, AN1-type domain 2A

chr7_-_141327700 0.492 ENSMUST00000080553.7
Deaf1
deformed epidermal autoregulatory factor 1 (Drosophila)
chr17_-_50094277 0.492 ENSMUST00000113195.1
Rftn1
raftlin lipid raft linker 1
chr9_+_64235201 0.491 ENSMUST00000039011.3
Uchl4
ubiquitin carboxyl-terminal esterase L4
chr10_-_95416850 0.491 ENSMUST00000020215.9
Socs2
suppressor of cytokine signaling 2
chr12_-_79172609 0.488 ENSMUST00000055262.6
Vti1b
vesicle transport through interaction with t-SNAREs 1B
chr9_+_18292267 0.487 ENSMUST00000001825.7
Chordc1
cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1
chr4_+_40722461 0.487 ENSMUST00000030118.3
Dnaja1
DnaJ (Hsp40) homolog, subfamily A, member 1
chr1_-_36273425 0.486 ENSMUST00000056946.6
Neurl3
neuralized homolog 3 homolog (Drosophila)
chr16_-_22265950 0.478 ENSMUST00000161286.1
Tra2b
transformer 2 beta homolog (Drosophila)
chr5_-_100820929 0.472 ENSMUST00000117364.1
ENSMUST00000055245.6
Fam175a

family with sequence similarity 175, member A

chr10_+_127642975 0.472 ENSMUST00000092074.5
ENSMUST00000120279.1
Stat6

signal transducer and activator of transcription 6

chr2_-_35442101 0.453 ENSMUST00000131745.1
Ggta1
glycoprotein galactosyltransferase alpha 1, 3
chr2_-_37359274 0.453 ENSMUST00000009174.8
Pdcl
phosducin-like
chr19_-_5366285 0.451 ENSMUST00000170010.1
Banf1
barrier to autointegration factor 1
chr11_-_23497867 0.451 ENSMUST00000128559.1
ENSMUST00000147157.1
ENSMUST00000109539.1
Ahsa2


AHA1, activator of heat shock protein ATPase 2


chrX_-_73659724 0.450 ENSMUST00000114473.1
ENSMUST00000002087.7
Pnck

pregnancy upregulated non-ubiquitously expressed CaM kinase

chr9_-_44440868 0.450 ENSMUST00000098837.1
Foxr1
forkhead box R1
chr9_-_105495130 0.439 ENSMUST00000038118.7
Atp2c1
ATPase, Ca++-sequestering
chr8_+_27085520 0.436 ENSMUST00000178514.1
ENSMUST00000033876.7
Gpr124

G protein-coupled receptor 124

chr1_+_57774842 0.431 ENSMUST00000167085.1
Spats2l
spermatogenesis associated, serine-rich 2-like
chr7_-_130519465 0.431 ENSMUST00000035458.7
ENSMUST00000033139.7
Ate1

arginyltransferase 1

chr1_-_52817503 0.428 ENSMUST00000162576.1
Inpp1
inositol polyphosphate-1-phosphatase
chr6_-_118562226 0.424 ENSMUST00000112830.1
Ankrd26
ankyrin repeat domain 26
chr2_-_75938407 0.424 ENSMUST00000099996.3
Ttc30b
tetratricopeptide repeat domain 30B
chr2_-_118256929 0.424 ENSMUST00000028820.6
ENSMUST00000028821.3
Fsip1

fibrous sheath-interacting protein 1

chr5_-_143180721 0.422 ENSMUST00000164068.1
ENSMUST00000049861.4
ENSMUST00000165318.1
Rbak


RB-associated KRAB repressor


chr11_-_70459957 0.413 ENSMUST00000019064.2
Cxcl16
chemokine (C-X-C motif) ligand 16
chr1_-_162859684 0.410 ENSMUST00000131058.1
Fmo1
flavin containing monooxygenase 1
chr13_-_52929458 0.406 ENSMUST00000123599.1
Auh
AU RNA binding protein/enoyl-coenzyme A hydratase
chr2_-_113829069 0.401 ENSMUST00000024005.7
Scg5
secretogranin V
chr6_+_125049952 0.401 ENSMUST00000088294.5
ENSMUST00000032481.7
Acrbp

proacrosin binding protein

chr9_+_118040475 0.390 ENSMUST00000044454.5
Azi2
5-azacytidine induced gene 2
chr2_-_7081207 0.386 ENSMUST00000114923.2
ENSMUST00000182706.1
Celf2

CUGBP, Elav-like family member 2

chr18_+_77065195 0.386 ENSMUST00000114777.2
Pias2
protein inhibitor of activated STAT 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 12.1 GO:0045583 regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585)
1.1 3.4 GO:0035799 ureter maturation(GO:0035799)
0.9 2.6 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.7 2.8 GO:1901252 regulation of intracellular transport of viral material(GO:1901252)
0.7 2.0 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.6 1.9 GO:0002842 positive regulation of T cell mediated immune response to tumor cell(GO:0002842) protein import into mitochondrial intermembrane space(GO:0045041)
0.5 2.1 GO:0021564 glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564)
0.5 1.6 GO:1901079 positive regulation of relaxation of muscle(GO:1901079)
0.5 3.1 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.5 1.4 GO:1903538 meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.4 1.3 GO:0071492 cellular response to UV-A(GO:0071492)
0.4 3.0 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
0.4 1.3 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.4 1.5 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.4 1.1 GO:0019043 establishment of viral latency(GO:0019043)
0.4 2.9 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.3 1.2 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.3 0.9 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.3 1.7 GO:0048254 snoRNA localization(GO:0048254)
0.3 0.8 GO:0002636 positive regulation of germinal center formation(GO:0002636)
0.3 2.6 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.2 1.2 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.2 0.7 GO:0031554 regulation of DNA-templated transcription, termination(GO:0031554)
0.2 0.7 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.2 0.9 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.2 1.1 GO:0060178 regulation of exocyst localization(GO:0060178)
0.2 0.9 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.2 1.3 GO:0042535 positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.2 3.6 GO:0034453 microtubule anchoring(GO:0034453)
0.2 1.6 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.2 1.0 GO:0042228 interleukin-8 biosynthetic process(GO:0042228)
0.2 2.4 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.2 1.1 GO:0007021 tubulin complex assembly(GO:0007021)
0.2 0.7 GO:0060715 syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
0.2 1.2 GO:0019348 dolichol metabolic process(GO:0019348)
0.2 0.6 GO:0002188 translation reinitiation(GO:0002188)
0.2 0.5 GO:0035771 interleukin-4-mediated signaling pathway(GO:0035771)
0.2 0.5 GO:1902605 heterotrimeric G-protein complex assembly(GO:1902605)
0.2 0.6 GO:1900533 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.1 0.4 GO:0016598 protein arginylation(GO:0016598)
0.1 0.9 GO:0015862 uridine transport(GO:0015862)
0.1 1.3 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.1 0.7 GO:0070197 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.1 0.5 GO:0002484 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway(GO:0002484) antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent(GO:0002485)
0.1 0.3 GO:0001803 antibody-dependent cellular cytotoxicity(GO:0001788) type III hypersensitivity(GO:0001802) regulation of type III hypersensitivity(GO:0001803) positive regulation of type III hypersensitivity(GO:0001805)
0.1 1.4 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.1 1.1 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.1 0.5 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.1 3.7 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.1 1.3 GO:0071318 cellular response to ATP(GO:0071318)
0.1 1.1 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.1 0.5 GO:0044565 dendritic cell proliferation(GO:0044565)
0.1 0.5 GO:0033580 protein glycosylation at cell surface(GO:0033575) protein galactosylation at cell surface(GO:0033580) protein galactosylation(GO:0042125)
0.1 0.8 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 0.5 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.1 0.7 GO:0051036 regulation of endosome size(GO:0051036) receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.1 0.7 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.1 0.3 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 0.6 GO:0002553 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.1 0.4 GO:0032627 interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667)
0.1 5.9 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1 0.8 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.1 1.0 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.1 0.7 GO:0097264 self proteolysis(GO:0097264)
0.1 0.7 GO:0071361 cellular response to ethanol(GO:0071361)
0.1 0.3 GO:0009174 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.1 0.7 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.1 0.5 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.1 0.3 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.1 0.7 GO:0090037 positive regulation of protein kinase C signaling(GO:0090037)
0.1 0.4 GO:0034141 positive regulation of toll-like receptor 3 signaling pathway(GO:0034141)
0.1 0.3 GO:0097527 necroptotic signaling pathway(GO:0097527)
0.1 0.5 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.1 0.7 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.1 0.2 GO:0010248 B cell negative selection(GO:0002352) response to mycotoxin(GO:0010046) establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.1 1.2 GO:0001553 luteinization(GO:0001553)
0.1 0.4 GO:0098707 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.1 0.2 GO:1904154 protein localization to endoplasmic reticulum exit site(GO:0070973) positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.1 0.2 GO:0015793 glycerol transport(GO:0015793)
0.1 0.8 GO:0035988 chondrocyte proliferation(GO:0035988)
0.1 1.1 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.1 1.3 GO:0021702 cerebellar Purkinje cell differentiation(GO:0021702)
0.1 0.8 GO:1990403 embryonic brain development(GO:1990403)
0.0 0.5 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.5 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.0 0.2 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.0 0.4 GO:0009404 toxin metabolic process(GO:0009404)
0.0 0.9 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.1 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.0 0.5 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.0 0.3 GO:0032261 purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264)
0.0 0.4 GO:0060766 negative regulation of androgen receptor signaling pathway(GO:0060766)
0.0 0.5 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.7 GO:0051531 NFAT protein import into nucleus(GO:0051531)
0.0 0.1 GO:0009414 response to water deprivation(GO:0009414)
0.0 0.2 GO:0019695 choline metabolic process(GO:0019695)
0.0 0.1 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.0 0.1 GO:0018307 tRNA wobble position uridine thiolation(GO:0002143) Mo-molybdopterin cofactor biosynthetic process(GO:0006777) enzyme active site formation(GO:0018307) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.0 1.4 GO:0046834 lipid phosphorylation(GO:0046834)
0.0 0.7 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.1 GO:0035928 rRNA import into mitochondrion(GO:0035928)
0.0 1.4 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.2 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.3 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.0 0.4 GO:0010818 T cell chemotaxis(GO:0010818)
0.0 1.7 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.2 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.0 0.5 GO:0033599 regulation of mammary gland epithelial cell proliferation(GO:0033599)
0.0 0.7 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 1.3 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.2 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.9 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.1 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.1 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.4 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 1.0 GO:0043954 cellular component maintenance(GO:0043954)
0.0 0.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.2 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.2 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.5 GO:0072673 lamellipodium morphogenesis(GO:0072673)
0.0 0.4 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.9 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0 0.8 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.0 0.3 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.4 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 1.3 GO:0009408 response to heat(GO:0009408)
0.0 0.2 GO:0042359 vitamin D metabolic process(GO:0042359)
0.0 0.3 GO:0060965 negative regulation of gene silencing by miRNA(GO:0060965)
0.0 0.3 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.6 GO:0070232 regulation of T cell apoptotic process(GO:0070232)
0.0 0.3 GO:0045103 intermediate filament-based process(GO:0045103)
0.0 0.1 GO:0019530 taurine metabolic process(GO:0019530)
0.0 0.0 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.0 0.1 GO:0061084 negative regulation of protein refolding(GO:0061084)
0.0 0.1 GO:0090383 phagosome acidification(GO:0090383)
0.0 0.2 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 12.1 GO:0097226 sperm mitochondrial sheath(GO:0097226)
0.6 2.9 GO:0036449 microtubule minus-end(GO:0036449)
0.4 2.4 GO:0097512 cardiac myofibril(GO:0097512)
0.4 1.6 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.4 4.2 GO:0042612 MHC class I protein complex(GO:0042612)
0.3 5.9 GO:0042588 zymogen granule(GO:0042588)
0.3 1.2 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.2 1.7 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.2 2.8 GO:0046930 pore complex(GO:0046930)
0.2 0.5 GO:0030905 retromer, tubulation complex(GO:0030905)
0.1 2.1 GO:0005614 interstitial matrix(GO:0005614)
0.1 1.0 GO:0042382 paraspeckles(GO:0042382)
0.1 1.5 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.7 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.8 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.8 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 0.5 GO:0031021 interphase microtubule organizing center(GO:0031021)
0.1 0.3 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.1 0.8 GO:0031415 NatA complex(GO:0031415)
0.1 0.5 GO:0000938 GARP complex(GO:0000938)
0.1 1.3 GO:0042101 T cell receptor complex(GO:0042101)
0.1 0.6 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 0.6 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.1 1.1 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.1 1.1 GO:0071564 npBAF complex(GO:0071564)
0.1 0.9 GO:0036038 MKS complex(GO:0036038)
0.1 0.5 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.1 0.4 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0 0.9 GO:0000800 lateral element(GO:0000800)
0.0 0.4 GO:0097433 dense body(GO:0097433)
0.0 0.3 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 3.3 GO:0005581 collagen trimer(GO:0005581)
0.0 0.4 GO:0060091 kinocilium(GO:0060091)
0.0 1.6 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.7 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 6.0 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.3 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.2 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.9 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 3.6 GO:0031225 anchored component of membrane(GO:0031225)
0.0 2.1 GO:0005604 basement membrane(GO:0005604)
0.0 0.3 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.5 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.3 GO:0061700 GATOR2 complex(GO:0061700)
0.0 2.5 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.7 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 1.0 GO:0016235 aggresome(GO:0016235)
0.0 0.5 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.3 GO:0043196 varicosity(GO:0043196)
0.0 0.5 GO:0001772 immunological synapse(GO:0001772)
0.0 0.3 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.5 GO:0005921 gap junction(GO:0005921)
0.0 0.1 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.4 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.1 GO:0033503 HULC complex(GO:0033503)
0.0 0.7 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.3 GO:0034451 centriolar satellite(GO:0034451)
0.0 1.9 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.3 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.0 GO:0044301 climbing fiber(GO:0044301) parallel fiber(GO:1990032)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 9.9 GO:0002135 CTP binding(GO:0002135)
0.6 3.1 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.5 1.4 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.4 3.1 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.4 1.3 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.4 1.2 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.4 2.6 GO:0043199 sulfate binding(GO:0043199)
0.3 4.2 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.3 1.9 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.3 1.2 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.3 2.0 GO:0016018 cyclosporin A binding(GO:0016018)
0.3 1.0 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441)
0.2 0.7 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.2 0.7 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.2 0.7 GO:0004492 methylmalonyl-CoA decarboxylase activity(GO:0004492)
0.2 0.7 GO:0004155 6,7-dihydropteridine reductase activity(GO:0004155)
0.2 1.7 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.2 2.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.2 7.3 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.2 0.9 GO:0050700 CARD domain binding(GO:0050700)
0.2 1.1 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021)
0.2 0.7 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.2 1.3 GO:0046790 virion binding(GO:0046790)
0.1 2.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.7 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.1 0.5 GO:1990460 leptin receptor binding(GO:1990460)
0.1 1.4 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.1 1.1 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.5 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.1 0.4 GO:0001729 ceramide kinase activity(GO:0001729)
0.1 0.7 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 1.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 0.3 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.1 0.3 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.1 3.0 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.1 0.4 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.5 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1 0.8 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.1 0.5 GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.1 0.4 GO:0004565 beta-galactosidase activity(GO:0004565)
0.1 0.3 GO:0034618 arginine binding(GO:0034618)
0.1 0.5 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.1 0.3 GO:0019770 IgG receptor activity(GO:0019770)
0.1 0.5 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.1 0.2 GO:0015254 glycerol channel activity(GO:0015254)
0.1 0.4 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 0.4 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.1 0.8 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 0.2 GO:0004046 aminoacylase activity(GO:0004046)
0.1 0.6 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.1 0.8 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.9 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 5.1 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0 0.4 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.1 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.0 1.3 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.4 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.6 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.3 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.8 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 1.1 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 1.6 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.4 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.0 0.5 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 1.3 GO:0030291 protein serine/threonine kinase inhibitor activity(GO:0030291)
0.0 0.2 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.0 0.2 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.1 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.0 0.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 1.9 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.2 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.9 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.7 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.2 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 1.1 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.2 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 1.1 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.2 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.0 0.1 GO:0032564 dATP binding(GO:0032564)
0.0 0.2 GO:0005243 gap junction channel activity(GO:0005243)
0.0 1.7 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.3 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.7 GO:0016504 peptidase activator activity(GO:0016504)
0.0 0.2 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.1 GO:0070728 leucine binding(GO:0070728)
0.0 0.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.2 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.4 GO:0070717 poly-purine tract binding(GO:0070717)
0.0 0.1 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 0.2 GO:0051400 BH domain binding(GO:0051400)
0.0 0.3 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.3 GO:0008373 sialyltransferase activity(GO:0008373)
0.0 0.5 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.5 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.2 GO:0102391 decanoate--CoA ligase activity(GO:0102391)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 12.1 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.1 2.0 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.1 1.5 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.1 0.7 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.1 1.3 PID_IL6_7_PATHWAY IL6-mediated signaling events
0.0 1.4 PID_ANGIOPOIETIN_RECEPTOR_PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 1.5 PID_FAS_PATHWAY FAS (CD95) signaling pathway
0.0 1.6 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 3.1 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.0 1.3 ST_P38_MAPK_PATHWAY p38 MAPK Pathway
0.0 0.6 PID_IL2_PI3K_PATHWAY IL2 signaling events mediated by PI3K
0.0 0.3 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 6.5 PID_PDGFRB_PATHWAY PDGFR-beta signaling pathway
0.0 1.1 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.0 4.0 PID_CMYB_PATHWAY C-MYB transcription factor network
0.0 4.3 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.5 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.5 PID_TCPTP_PATHWAY Signaling events mediated by TCPTP
0.0 0.3 PID_CD40_PATHWAY CD40/CD40L signaling
0.0 0.5 PID_IL2_1PATHWAY IL2-mediated signaling events
0.0 0.3 PID_PRL_SIGNALING_EVENTS_PATHWAY Signaling events mediated by PRL
0.0 0.2 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.5 PID_ATM_PATHWAY ATM pathway
0.0 0.2 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 12.1 REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.5 3.0 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.2 0.7 REACTOME_SEROTONIN_RECEPTORS Genes involved in Serotonin receptors
0.2 3.3 REACTOME_HYALURONAN_METABOLISM Genes involved in Hyaluronan metabolism
0.1 1.3 REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 1.1 REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1 1.6 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 2.6 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 2.7 REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 2.2 REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS Genes involved in Activation of BH3-only proteins
0.1 2.3 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.1 1.2 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 4.5 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.1 1.3 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.1 0.8 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.1 0.4 REACTOME_IRAK1_RECRUITS_IKK_COMPLEX Genes involved in IRAK1 recruits IKK complex
0.1 1.1 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.0 8.6 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 1.2 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.0 0.5 REACTOME_ERKS_ARE_INACTIVATED Genes involved in ERKs are inactivated
0.0 1.2 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 1.9 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.0 1.5 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.2 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.5 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.6 REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.3 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.3 REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.5 REACTOME_ACTIVATED_TAK1_MEDIATES_P38_MAPK_ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.3 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 1.4 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.4 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.4 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.9 REACTOME_DESTABILIZATION_OF_MRNA_BY_AUF1_HNRNP_D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.2 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.5 REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.3 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.0 1.4 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.3 REACTOME_PYRIMIDINE_METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.2 REACTOME_INTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis