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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr7_-_141010759	9.992	ENSMUST00000026565.6	Ifitm3	interferon induced transmembrane protein 3
chr4_-_40239779	6.492	ENSMUST00000037907.6	Ddx58	DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr6_-_39118211	5.605	ENSMUST00000038398.6	Parp12	poly (ADP-ribose) polymerase family, member 12
chr17_-_6782775	5.415	ENSMUST00000064234.6	Ezr	ezrin
chr11_+_88999376	4.392	ENSMUST00000100627.2 ENSMUST00000107896.3 ENSMUST00000000284.6	Trim25	tripartite motif-containing 25
chr16_+_35938972	4.001	ENSMUST00000023622.6 ENSMUST00000114877.1	Parp9	poly (ADP-ribose) polymerase family, member 9
chr2_-_77519565	3.864	ENSMUST00000111830.2	Zfp385b	zinc finger protein 385B
chr4_-_40239700	3.698	ENSMUST00000142055.1	Ddx58	DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr19_+_55741810	3.332	ENSMUST00000111657.3 ENSMUST00000061496.9 ENSMUST00000041717.7 ENSMUST00000111662.4	Tcf7l2	transcription factor 7 like 2, T cell specific, HMG box
chr3_+_138065052	2.461	ENSMUST00000163080.2	1110002E22Rik	RIKEN cDNA 1110002E22 gene
chr4_-_136886187	2.383	ENSMUST00000046384.8	C1qb	complement component 1, q subcomponent, beta polypeptide
chr1_-_163313661	2.213	ENSMUST00000174397.1 ENSMUST00000075805.6 ENSMUST00000027878.7	Prrx1	paired related homeobox 1
chr16_+_35938470	1.836	ENSMUST00000114878.1	Parp9	poly (ADP-ribose) polymerase family, member 9
chr7_+_128523576	1.550	ENSMUST00000033136.7	Bag3	BCL2-associated athanogene 3
chr17_+_34203527	1.326	ENSMUST00000025197.5	Tap2	transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
chr2_-_77170592	1.269	ENSMUST00000164114.2 ENSMUST00000049544.7	Ccdc141	coiled-coil domain containing 141
chr7_-_141266415	1.159	ENSMUST00000106023.1 ENSMUST00000097952.2 ENSMUST00000026571.4	Irf7	interferon regulatory factor 7
chr9_+_45042425	1.150	ENSMUST00000034600.4	Mpzl2	myelin protein zero-like 2
chr15_+_9436028	1.127	ENSMUST00000042360.3	Capsl	calcyphosine-like
chr7_+_49246131	1.075	ENSMUST00000064395.6	Nav2	neuron navigator 2
chr12_-_31950210	1.064	ENSMUST00000176084.1 ENSMUST00000176103.1 ENSMUST00000167458.2	Hbp1	high mobility group box transcription factor 1
chrX_+_77511002	1.010	ENSMUST00000088217.5	Tbl1x	transducin (beta)-like 1 X-linked
chr11_+_72689997	1.004	ENSMUST00000155998.1	Ankfy1	ankyrin repeat and FYVE domain containing 1
chr12_-_31950170	0.982	ENSMUST00000176520.1	Hbp1	high mobility group box transcription factor 1
chr10_+_80249106	0.965	ENSMUST00000105364.1	Ndufs7	NADH dehydrogenase (ubiquinone) Fe-S protein 7
chr10_+_80249441	0.926	ENSMUST00000020361.6	Ndufs7	NADH dehydrogenase (ubiquinone) Fe-S protein 7
chr11_+_101582236	0.822	ENSMUST00000039581.7 ENSMUST00000100403.2 ENSMUST00000107194.1 ENSMUST00000128614.1	Tmem106a	transmembrane protein 106A
chr9_+_20868628	0.789	ENSMUST00000043911.7	A230050P20Rik	RIKEN cDNA A230050P20 gene
chr11_-_78984831	0.788	ENSMUST00000073001.4 ENSMUST00000108269.3	Lgals9	lectin, galactose binding, soluble 9
chr16_-_5255923	0.754	ENSMUST00000139584.1 ENSMUST00000064635.5	Fam86	family with sequence similarity 86
chr9_+_55326913	0.724	ENSMUST00000085754.3 ENSMUST00000034862.4	AI118078	expressed sequence AI118078
chr15_-_76243401	0.705	ENSMUST00000165738.1 ENSMUST00000075689.6	Parp10	poly (ADP-ribose) polymerase family, member 10
chr11_-_78984946	0.657	ENSMUST00000108268.3	Lgals9	lectin, galactose binding, soluble 9
chr5_+_99979061	0.649	ENSMUST00000046721.1	4930524J08Rik	RIKEN cDNA 4930524J08 gene
chr1_+_52119438	0.628	ENSMUST00000070968.7	Stat1	signal transducer and activator of transcription 1
chr2_-_51934644	0.599	ENSMUST00000165313.1	Rbm43	RNA binding motif protein 43
chrM_+_9452	0.588	ENSMUST00000082411.1	mt-Nd3	mitochondrially encoded NADH dehydrogenase 3
chr12_-_31950535	0.566	ENSMUST00000172314.2	Hbp1	high mobility group box transcription factor 1
chr1_-_184732616	0.558	ENSMUST00000048572.6	Hlx	H2.0-like homeobox
chr2_-_69586021	0.520	ENSMUST00000100051.2 ENSMUST00000092551.4 ENSMUST00000080953.5	Lrp2	low density lipoprotein receptor-related protein 2
chr15_+_96287518	0.513	ENSMUST00000134985.2 ENSMUST00000096250.4	Arid2	AT rich interactive domain 2 (ARID, RFX-like)
chr16_-_67620805	0.513	ENSMUST00000120594.1	Cadm2	cell adhesion molecule 2
chr3_-_142395661	0.503	ENSMUST00000029941.9 ENSMUST00000168967.2 ENSMUST00000090134.5 ENSMUST00000058626.8	Pdlim5	PDZ and LIM domain 5
chr12_+_26469204	0.500	ENSMUST00000020969.3	Cmpk2	cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chrM_+_8600	0.494	ENSMUST00000082409.1	mt-Co3	mitochondrially encoded cytochrome c oxidase III
chr8_-_105568298	0.479	ENSMUST00000005849.5	Agrp	agouti related protein
chr6_-_13608011	0.462	ENSMUST00000031554.2	Tmem168	transmembrane protein 168
chr16_-_67620880	0.460	ENSMUST00000114292.1 ENSMUST00000120898.1	Cadm2	cell adhesion molecule 2
chr16_+_23609895	0.434	ENSMUST00000038423.5	Rtp4	receptor transporter protein 4
chr4_+_108460000	0.429	ENSMUST00000097925.2	Zcchc11	zinc finger, CCHC domain containing 11
chr16_-_35871544	0.427	ENSMUST00000042665.8	Parp14	poly (ADP-ribose) polymerase family, member 14
chr6_+_57580992	0.355	ENSMUST00000031817.8	Herc6	hect domain and RLD 6
chr11_+_72301613	0.339	ENSMUST00000151440.1 ENSMUST00000146233.1 ENSMUST00000140842.2	Xaf1	XIAP associated factor 1
chr9_-_123862023	0.307	ENSMUST00000182350.1 ENSMUST00000078755.2	Xcr1	chemokine (C motif) receptor 1
chr16_-_55838827	0.298	ENSMUST00000096026.2 ENSMUST00000036273.6 ENSMUST00000114457.1	Nfkbiz	nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta
chr9_-_123851855	0.249	ENSMUST00000184082.1 ENSMUST00000167595.2	Fyco1	FYVE and coiled-coil domain containing 1
chr6_-_87838671	0.212	ENSMUST00000089497.4	Isy1	ISY1 splicing factor homolog (S. cerevisiae)
chr7_-_65370908	0.188	ENSMUST00000032729.6	Tjp1	tight junction protein 1
chr17_-_78882508	0.144	ENSMUST00000024884.4	Eif2ak2	eukaryotic translation initiation factor 2-alpha kinase 2
chr11_+_69966896	0.138	ENSMUST00000151515.1	Cldn7	claudin 7
chr9_-_111057235	0.081	ENSMUST00000111888.1	Ccrl2	chemokine (C-C motif) receptor-like 2
chr3_+_142496924	0.066	ENSMUST00000090127.2	Gbp5	guanylate binding protein 5
chr9_-_14381242	0.014	ENSMUST00000167549.1	Endod1	endonuclease domain containing 1

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.5	10.2	GO:0009597	detection of virus(GO:0009597)
1.8	5.4	GO:1900041	intestinal D-glucose absorption(GO:0001951) negative regulation of interleukin-2 secretion(GO:1900041) terminal web assembly(GO:1902896)
0.8	14.4	GO:0046597	negative regulation of viral entry into host cell(GO:0046597)
0.6	5.8	GO:0060330	regulation of response to interferon-gamma(GO:0060330)
0.5	1.4	GO:1902714	negative regulation of interferon-gamma secretion(GO:1902714)
0.4	1.3	GO:0002489	antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489)
0.4	3.3	GO:0048625	myoblast fate commitment(GO:0048625)
0.3	2.6	GO:0010745	negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.3	1.1	GO:0070212	protein poly-ADP-ribosylation(GO:0070212)
0.3	1.1	GO:0021564	glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564)
0.2	1.2	GO:0034124	regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
0.2	2.2	GO:0048664	neuron fate determination(GO:0048664)
0.2	1.0	GO:0032439	endosome localization(GO:0032439) positive regulation of pinocytosis(GO:0048549)
0.2	0.5	GO:0046077	dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate metabolic process(GO:0009138) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077)
0.2	0.6	GO:0034239	regulation of macrophage fusion(GO:0034239)
0.1	0.4	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1	2.4	GO:0006958	complement activation, classical pathway(GO:0006958)
0.1	0.6	GO:0045629	positive regulation of T-helper 1 cell differentiation(GO:0045627) negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1	1.6	GO:0097201	negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.1	0.2	GO:0000389	generation of catalytic spliceosome for second transesterification step(GO:0000350) mRNA 3'-splice site recognition(GO:0000389)
0.1	0.2	GO:1901098	positive regulation of autophagosome maturation(GO:1901098)
0.1	0.5	GO:0008343	adult feeding behavior(GO:0008343)
0.0	1.9	GO:0097031	NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0	0.5	GO:0060982	coronary artery morphogenesis(GO:0060982)
0.0	0.2	GO:1900225	NLRP3 inflammasome complex assembly(GO:0044546) regulation of NLRP3 inflammasome complex assembly(GO:1900225)
0.0	3.9	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0	0.3	GO:0010587	miRNA catabolic process(GO:0010587)
0.0	1.3	GO:0051642	centrosome localization(GO:0051642)
0.0	0.5	GO:0044872	lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0	0.8	GO:0034340	response to type I interferon(GO:0034340)
0.0	0.2	GO:0090557	establishment of endothelial intestinal barrier(GO:0090557)
0.0	1.0	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0	0.6	GO:0071385	cellular response to glucocorticoid stimulus(GO:0071385)
0.0	0.9	GO:0071594	T cell differentiation in thymus(GO:0033077) thymocyte aggregation(GO:0071594)
0.0	1.0	GO:0043627	response to estrogen(GO:0043627)
0.0	0.3	GO:0035456	response to interferon-beta(GO:0035456)
0.0	0.5	GO:0003301	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.8	5.4	GO:0098592	cytoplasmic side of apical plasma membrane(GO:0098592)
0.4	3.3	GO:0070369	beta-catenin-TCF7L2 complex(GO:0070369)
0.2	1.3	GO:0042825	TAP complex(GO:0042825)
0.1	1.0	GO:0044352	pinosome(GO:0044352) macropinosome(GO:0044354)
0.1	10.2	GO:0032587	ruffle membrane(GO:0032587)
0.1	0.5	GO:0005796	Golgi lumen(GO:0005796)
0.1	1.1	GO:0005614	interstitial matrix(GO:0005614)
0.1	2.5	GO:0045271	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0	2.4	GO:0005581	collagen trimer(GO:0005581)
0.0	0.2	GO:0071012	catalytic step 1 spliceosome(GO:0071012)
0.0	1.0	GO:0032809	neuronal cell body membrane(GO:0032809)
0.0	10.2	GO:0045177	apical part of cell(GO:0045177)
0.0	3.9	GO:0001650	fibrillar center(GO:0001650)
0.0	1.0	GO:0005876	spindle microtubule(GO:0005876)
0.0	0.5	GO:0090544	BAF-type complex(GO:0090544)
0.0	2.1	GO:0030018	Z disc(GO:0030018)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	12.6	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.4	5.4	GO:0044548	S100 protein binding(GO:0044548)
0.3	1.3	GO:0015433	peptide antigen-transporting ATPase activity(GO:0015433) tapasin binding(GO:0046980)
0.3	4.4	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.2	1.4	GO:0016936	galactoside binding(GO:0016936)
0.2	0.5	GO:0042954	lipoprotein transporter activity(GO:0042954)
0.2	1.6	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
0.2	0.5	GO:0004127	cytidylate kinase activity(GO:0004127) uridylate kinase activity(GO:0009041)
0.2	3.3	GO:0070016	gamma-catenin binding(GO:0045295) armadillo repeat domain binding(GO:0070016)
0.1	1.9	GO:0048038	quinone binding(GO:0048038)
0.1	10.3	GO:0003725	double-stranded RNA binding(GO:0003725)
0.1	0.4	GO:0050265	RNA uridylyltransferase activity(GO:0050265)
0.1	0.6	GO:0031730	CCR5 chemokine receptor binding(GO:0031730)
0.1	2.2	GO:0071837	HMG box domain binding(GO:0071837)
0.0	3.9	GO:0002039	p53 binding(GO:0002039)
0.0	0.5	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0	0.1	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.0	0.5	GO:0005184	neuropeptide hormone activity(GO:0005184)
0.0	0.6	GO:0050136	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0	0.5	GO:0004129	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0	0.2	GO:0071253	connexin binding(GO:0071253)
0.0	1.2	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0	2.6	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	5.4	PID_SYNDECAN_2_PATHWAY	Syndecan-2-mediated signaling events
0.1	2.6	PID_MYC_PATHWAY	C-MYC pathway
0.1	0.6	ST_TYPE_I_INTERFERON_PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.0	3.3	PID_AP1_PATHWAY	AP-1 transcription factor network
0.0	0.5	PID_SYNDECAN_3_PATHWAY	Syndecan-3-mediated signaling events
0.0	3.8	NABA_ECM_AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	0.5	PID_HEDGEHOG_2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	1.0	PID_BETA_CATENIN_NUC_PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.0	0.6	PID_IL12_2PATHWAY	IL12-mediated signaling events
0.0	0.8	PID_SMAD2_3NUCLEAR_PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.0	0.4	PID_IL4_2PATHWAY	IL4-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.0	15.7	REACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.4	2.4	REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.3	11.0	REACTOME_INTERFERON_ALPHA_BETA_SIGNALING	Genes involved in Interferon alpha/beta signaling
0.1	5.4	REACTOME_RECYCLING_PATHWAY_OF_L1	Genes involved in Recycling pathway of L1
0.1	1.3	REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.2	REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	1.0	REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.5	REACTOME_STEROID_HORMONES	Genes involved in Steroid hormones
0.0	1.0	REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	1.9	REACTOME_RESPIRATORY_ELECTRON_TRANSPORT	Genes involved in Respiratory electron transport
0.0	0.3	REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES	Genes involved in Chemokine receptors bind chemokines

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