Motif ID: Klf13

Z-value: 0.557


Transcription factors associated with Klf13:

Gene SymbolEntrez IDGene Name
Klf13 ENSMUSG00000052040.9 Klf13

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Klf13mm10_v2_chr7_-_63938862_63938933-0.291.2e-02Click!


Activity profile for motif Klf13.

activity profile for motif Klf13


Sorted Z-values histogram for motif Klf13

Sorted Z-values for motif Klf13



Network of associatons between targets according to the STRING database.



First level regulatory network of Klf13

PNG image of the network

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Top targets:


Showing 1 to 20 of 115 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_+_56722372 3.188 ENSMUST00000038949.4
Adrb1
adrenergic receptor, beta 1
chr4_+_136143497 2.983 ENSMUST00000008016.2
Id3
inhibitor of DNA binding 3
chr18_+_37955544 2.224 ENSMUST00000070709.2
ENSMUST00000177058.1
ENSMUST00000169360.2
ENSMUST00000163591.2
ENSMUST00000091932.5
Rell2




RELT-like 2




chr11_+_70026815 2.026 ENSMUST00000135916.2
Dlg4
discs, large homolog 4 (Drosophila)
chr18_+_37955126 1.964 ENSMUST00000176902.1
ENSMUST00000176104.1
Rell2

RELT-like 2

chr14_+_54426902 1.926 ENSMUST00000010550.7
Mrpl52
mitochondrial ribosomal protein L52
chr7_+_19181159 1.816 ENSMUST00000120595.1
ENSMUST00000048502.8
Eml2

echinoderm microtubule associated protein like 2

chr10_-_62340514 1.758 ENSMUST00000099691.4
Hk1
hexokinase 1
chr12_-_14152038 1.659 ENSMUST00000020926.6
Fam84a
family with sequence similarity 84, member A
chr17_+_87282880 1.611 ENSMUST00000041110.5
ENSMUST00000125875.1
Ttc7

tetratricopeptide repeat domain 7

chr12_-_79172609 1.562 ENSMUST00000055262.6
Vti1b
vesicle transport through interaction with t-SNAREs 1B
chr18_+_67343564 1.514 ENSMUST00000025404.8
Cidea
cell death-inducing DNA fragmentation factor, alpha subunit-like effector A
chr6_+_83795205 1.448 ENSMUST00000113850.1
Nagk
N-acetylglucosamine kinase
chr8_+_83608175 1.400 ENSMUST00000005620.8
Dnajb1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr17_-_87282771 1.336 ENSMUST00000161759.1
4833418N02Rik
RIKEN cDNA 4833418N02 gene
chr19_-_42129043 1.305 ENSMUST00000018965.3
Avpi1
arginine vasopressin-induced 1
chr5_+_35757875 1.282 ENSMUST00000101280.3
ENSMUST00000054598.5
ENSMUST00000114205.1
ENSMUST00000114206.2
Ablim2



actin-binding LIM protein 2



chr6_-_82652856 1.256 ENSMUST00000160281.1
ENSMUST00000095786.5
Pole4

polymerase (DNA-directed), epsilon 4 (p12 subunit)

chr7_-_30563184 1.239 ENSMUST00000043898.6
Psenen
presenilin enhancer 2 homolog (C. elegans)
chr6_+_83794974 1.194 ENSMUST00000037376.7
Nagk
N-acetylglucosamine kinase

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 58 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.2 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.5 3.7 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
1.1 3.2 GO:1900133 renin secretion into blood stream(GO:0002001) regulation of renin secretion into blood stream(GO:1900133)
0.1 3.0 GO:0030903 notochord development(GO:0030903)
0.2 2.0 GO:0099628 receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
0.0 1.9 GO:0032543 mitochondrial translation(GO:0032543)
0.3 1.8 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.3 1.8 GO:0061718 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1 1.8 GO:0030488 tRNA methylation(GO:0030488)
0.0 1.7 GO:0000187 activation of MAPK activity(GO:0000187)
0.1 1.6 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 1.6 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.4 1.5 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 1.5 GO:0034605 cellular response to heat(GO:0034605)
0.5 1.4 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.1 1.4 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.2 1.3 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 1.3 GO:0043966 histone H3 acetylation(GO:0043966)
0.4 1.2 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
0.1 1.2 GO:0007220 Notch receptor processing(GO:0007220)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 30 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.2 GO:0005604 basement membrane(GO:0005604)
0.0 2.6 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 2.0 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 1.8 GO:0097228 sperm principal piece(GO:0097228)
0.0 1.8 GO:0072686 mitotic spindle(GO:0072686)
0.1 1.6 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 1.5 GO:0005811 lipid particle(GO:0005811)
0.3 1.4 GO:0099524 region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524)
0.2 1.4 GO:0097427 microtubule bundle(GO:0097427)
0.3 1.3 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.2 1.2 GO:0070765 gamma-secretase complex(GO:0070765)
0.1 1.2 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.3 1.0 GO:0044194 cytolytic granule(GO:0044194)
0.0 1.0 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 1.0 GO:0015030 Cajal body(GO:0015030)
0.2 0.9 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 0.9 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.9 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 0.8 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.8 GO:0032593 insulin-responsive compartment(GO:0032593)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 47 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 4.2 GO:0005518 collagen binding(GO:0005518)
1.2 3.7 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
1.1 3.2 GO:0051379 epinephrine binding(GO:0051379)
0.1 3.0 GO:0005504 fatty acid binding(GO:0005504)
0.3 2.0 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.2 1.9 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 1.9 GO:0003735 structural constituent of ribosome(GO:0003735)
0.4 1.8 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.2 1.8 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.2 1.6 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.2 1.4 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 1.4 GO:0001671 ATPase activator activity(GO:0001671)
0.2 1.3 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 1.3 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.2 1.2 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.2 1.2 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 1.1 GO:0005158 insulin receptor binding(GO:0005158)
0.2 1.0 GO:0030348 syntaxin-3 binding(GO:0030348)
0.1 1.0 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.2 0.9 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)

Gene overrepresentation in C2:CP category:

Showing 1 to 11 of 11 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 6.1 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 1.8 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.1 1.4 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 1.2 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.1 1.2 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.0 1.1 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 1.0 PID_AURORA_A_PATHWAY Aurora A signaling
0.0 1.0 PID_P73PATHWAY p73 transcription factor network
0.0 0.7 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.0 0.5 PID_RETINOIC_ACID_PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.3 PID_S1P_S1P1_PATHWAY S1P1 pathway

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 12 of 12 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 3.2 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 1.8 REACTOME_GLUCOSE_TRANSPORT Genes involved in Glucose transport
0.1 1.6 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 1.6 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.1 1.3 REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 1.3 REACTOME_GLYCOSPHINGOLIPID_METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 1.2 REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 1.2 REACTOME_REGULATED_PROTEOLYSIS_OF_P75NTR Genes involved in Regulated proteolysis of p75NTR
0.1 0.9 REACTOME_ENDOGENOUS_STEROLS Genes involved in Endogenous sterols
0.0 0.7 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.5 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.5 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA