Motif ID: Meox1

Z-value: 1.052


Transcription factors associated with Meox1:

Gene SymbolEntrez IDGene Name
Meox1 ENSMUSG00000001493.9 Meox1



Activity profile for motif Meox1.

activity profile for motif Meox1


Sorted Z-values histogram for motif Meox1

Sorted Z-values for motif Meox1



Network of associatons between targets according to the STRING database.



First level regulatory network of Meox1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 126 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_-_14621805 20.161 ENSMUST00000042221.7
 Slc26a7
solute carrier family 26, member 7
chr15_-_8710734 19.173 ENSMUST00000005493.7
 Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr6_-_36811361 17.262 ENSMUST00000101534.1
 Ptn
pleiotrophin
chr15_-_8710409 16.360 ENSMUST00000157065.1
 Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr3_-_59220150 13.894 ENSMUST00000170388.1
 P2ry12
purinergic receptor P2Y, G-protein coupled 12
chr5_-_134747241 13.826 ENSMUST00000015138.9
 Eln
elastin
chr7_-_140154712 12.379 ENSMUST00000059241.7
 Sprn
shadow of prion protein
chr4_-_14621494 11.674 ENSMUST00000149633.1
 Slc26a7
solute carrier family 26, member 7
chr15_-_37458523 11.650 ENSMUST00000116445.2
 Ncald
neurocalcin delta
chr15_+_92597104 11.605 ENSMUST00000035399.8
 Pdzrn4
PDZ domain containing RING finger 4
chr15_-_37459327 11.582 ENSMUST00000119730.1
ENSMUST00000120746.1
 Ncald

neurocalcin delta

chr5_+_107403496 10.733 ENSMUST00000049146.5
 Ephx4
epoxide hydrolase 4
chr4_-_14621669 10.646 ENSMUST00000143105.1
 Slc26a7
solute carrier family 26, member 7
chr8_+_66386292 9.332 ENSMUST00000039540.5
ENSMUST00000110253.2
 March1

membrane-associated ring finger (C3HC4) 1

chr14_-_103843685 8.219 ENSMUST00000172237.1
 Ednrb
endothelin receptor type B
chr9_+_34904913 7.552 ENSMUST00000045091.6
 Kirrel3
kin of IRRE like 3 (Drosophila)
chr9_-_95750335 7.001 ENSMUST00000053785.3
 Trpc1
transient receptor potential cation channel, subfamily C, member 1
chr3_-_121263314 6.786 ENSMUST00000029777.7
 Tmem56
transmembrane protein 56
chr2_+_125136692 6.610 ENSMUST00000099452.2
 Ctxn2
cortexin 2
chr3_+_13946368 6.257 ENSMUST00000171075.1
ENSMUST00000108372.2
 Ralyl

RALY RNA binding protein-like


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 63 entries
Log-likelihood per target Total log-likelihoodTermDescription
6.1 42.5 GO:0019532 oxalate transport(GO:0019532)
8.9 35.5 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.3 23.2 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
5.8 17.3 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.1 15.4 GO:0043149 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
4.6 13.9 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.0 12.6 GO:1902593 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593)
0.5 9.3 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.1 9.3 GO:0007416 synapse assembly(GO:0007416)
2.7 8.2 GO:0014826 vein smooth muscle contraction(GO:0014826)
1.0 8.1 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
1.5 7.6 GO:0002121 inter-male aggressive behavior(GO:0002121)
2.4 7.3 GO:0001193 maintenance of transcriptional fidelity during DNA-templated transcription elongation(GO:0001192) maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter(GO:0001193)
0.7 7.0 GO:0046541 saliva secretion(GO:0046541)
0.4 6.5 GO:0048240 sperm capacitation(GO:0048240)
0.3 6.1 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.9 5.6 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
1.4 5.5 GO:1900533 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
1.3 5.4 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.8 4.9 GO:1903056 positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 45 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 98.9 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 30.7 GO:0070062 extracellular exosome(GO:0070062)
0.2 17.3 GO:0031594 neuromuscular junction(GO:0031594)
4.6 13.8 GO:0071953 elastic fiber(GO:0071953)
0.1 12.4 GO:0031225 anchored component of membrane(GO:0031225)
0.3 9.3 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.2 8.5 GO:0031672 A band(GO:0031672)
0.9 8.1 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 7.6 GO:0043198 dendritic shaft(GO:0043198)
0.4 7.3 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
1.1 5.6 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 5.0 GO:0001650 fibrillar center(GO:0001650)
0.3 4.3 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 4.3 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 3.9 GO:0031965 nuclear membrane(GO:0031965)
0.1 3.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.3 3.4 GO:0005688 U6 snRNP(GO:0005688)
0.7 3.3 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.5 3.2 GO:0097443 sorting endosome(GO:0097443)
0.0 3.1 GO:0055037 recycling endosome(GO:0055037)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 59 entries
Log-likelihood per target Total log-likelihoodTermDescription
3.9 42.5 GO:0019531 secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531)
5.9 35.5 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.7 23.2 GO:0043014 alpha-tubulin binding(GO:0043014)
5.8 17.3 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
2.0 13.9 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled adenosine receptor activity(GO:0001609) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.3 11.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 9.6 GO:0005509 calcium ion binding(GO:0005509)
2.7 8.2 GO:0004962 endothelin receptor activity(GO:0004962)
1.3 8.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 7.6 GO:0030165 PDZ domain binding(GO:0030165)
0.3 7.5 GO:0042287 MHC protein binding(GO:0042287)
0.2 7.3 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.6 7.0 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 6.2 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
2.0 6.1 GO:0016748 succinyltransferase activity(GO:0016748)
0.8 5.6 GO:0000150 recombinase activity(GO:0000150)
0.5 5.5 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 5.4 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.1 4.9 GO:0070412 R-SMAD binding(GO:0070412)
0.0 4.6 GO:0017137 Rab GTPase binding(GO:0017137)

Gene overrepresentation in C2:CP category:

Showing 1 to 11 of 11 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.9 17.3 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.1 13.8 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 8.2 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events
0.1 7.4 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.2 6.5 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 3.3 PID_MTOR_4PATHWAY mTOR signaling pathway
0.1 3.2 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.0 2.2 PID_MAPK_TRK_PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 1.6 PID_NEPHRIN_NEPH1_PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 1.3 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.6 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 22 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 80.6 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
1.3 23.2 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.5 15.6 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
1.5 13.9 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.1 8.2 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.4 7.3 REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 6.2 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.3 6.1 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 3.5 REACTOME_ACTIVATION_OF_KAINATE_RECEPTORS_UPON_GLUTAMATE_BINDING Genes involved in Activation of Kainate Receptors upon glutamate binding
0.2 3.4 REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 3.1 REACTOME_FATTY_ACYL_COA_BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.2 3.0 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 3.0 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 3.0 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.1 1.9 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.1 1.6 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 1.3 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.0 1.3 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.9 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 0.7 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends