Motif ID: Mga

Z-value: 0.467


Transcription factors associated with Mga:

Gene SymbolEntrez IDGene Name
Mga ENSMUSG00000033943.9 Mga

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mgamm10_v2_chr2_+_119897212_1198973050.325.2e-03Click!


Activity profile for motif Mga.

activity profile for motif Mga


Sorted Z-values histogram for motif Mga

Sorted Z-values for motif Mga



Network of associatons between targets according to the STRING database.



First level regulatory network of Mga

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 73 entries
PromoterScoreRefseqGene SymbolGene Name
chr14_+_65805832 5.229 ENSMUST00000022612.3
 Pbk
PDZ binding kinase
chrX_+_35888808 4.175 ENSMUST00000033419.6
 Dock11
dedicator of cytokinesis 11
chr16_-_45844303 4.163 ENSMUST00000036355.6
 Phldb2
pleckstrin homology-like domain, family B, member 2
chr3_+_76075583 2.783 ENSMUST00000160261.1
 Fstl5
follistatin-like 5
chr8_-_61902669 2.509 ENSMUST00000121785.1
ENSMUST00000034057.7
 Palld

palladin, cytoskeletal associated protein

chr2_-_170131156 2.295 ENSMUST00000063710.6
 Zfp217
zinc finger protein 217
chr13_-_8870967 2.168 ENSMUST00000164183.2
 Wdr37
WD repeat domain 37
chr11_+_49203465 2.041 ENSMUST00000150284.1
ENSMUST00000109197.1
ENSMUST00000151228.1
 Zfp62


zinc finger protein 62


chr11_+_113657375 1.975 ENSMUST00000148736.1
ENSMUST00000142069.1
ENSMUST00000134418.1
 Cog1


component of oligomeric golgi complex 1


chr11_+_49203285 1.880 ENSMUST00000109198.1
ENSMUST00000137061.2
 Zfp62

zinc finger protein 62

chr5_+_137745730 1.853 ENSMUST00000100540.3
 Tsc22d4
TSC22 domain family, member 4
chr7_-_3720382 1.808 ENSMUST00000078451.6
 Pirb
paired Ig-like receptor B
chr5_-_124352233 1.785 ENSMUST00000111472.1
 Cdk2ap1
CDK2 (cyclin-dependent kinase 2)-associated protein 1
chr5_-_86676346 1.771 ENSMUST00000038448.6
 Tmprss11bnl
transmembrane protease, serine 11b N terminal like
chr7_+_27486910 1.741 ENSMUST00000008528.7
 Sertad1
SERTA domain containing 1
chr13_-_74482943 1.659 ENSMUST00000074369.6
 Zfp825
zinc finger protein 825
chr11_-_3931960 1.658 ENSMUST00000109990.1
ENSMUST00000020710.4
ENSMUST00000109989.3
ENSMUST00000109991.1
ENSMUST00000109993.2
 Tcn2




transcobalamin 2




chr7_+_13278778 1.629 ENSMUST00000098814.4
ENSMUST00000146998.1
ENSMUST00000185145.1
 Lig1


ligase I, DNA, ATP-dependent


chr2_+_144527718 1.557 ENSMUST00000028914.2
ENSMUST00000110017.2
 Polr3f

polymerase (RNA) III (DNA directed) polypeptide F

chr5_-_138619702 1.537 ENSMUST00000063262.4
 Zfp68
zinc finger protein 68

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 29 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.2 GO:0070303 negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303)
0.6 4.2 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.4 4.2 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 4.2 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.1 2.5 GO:0071803 keratinocyte development(GO:0003334) positive regulation of podosome assembly(GO:0071803)
0.0 2.3 GO:0007569 cell aging(GO:0007569)
0.0 2.0 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 2.0 GO:0060325 face morphogenesis(GO:0060325)
0.2 1.9 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 1.8 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.4 1.7 GO:0015889 cobalamin transport(GO:0015889)
0.2 1.6 GO:0033567 DNA replication, Okazaki fragment processing(GO:0033567)
0.0 1.6 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.3 1.3 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.1 1.0 GO:0044872 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.1 0.9 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0 0.9 GO:0006376 mRNA splice site selection(GO:0006376)
0.3 0.8 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.1 0.7 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.1 0.7 GO:0007602 phototransduction(GO:0007602)

Gene overrepresentation in cellular_component category:

Showing 1 to 17 of 17 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 4.2 GO:0045180 basal cortex(GO:0045180)
0.3 3.5 GO:0070545 PeBoW complex(GO:0070545)
0.1 2.5 GO:0002102 podosome(GO:0002102)
0.0 2.3 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 2.0 GO:0017119 Golgi transport complex(GO:0017119)
0.1 1.6 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 1.3 GO:0032040 small-subunit processome(GO:0032040)
0.1 1.2 GO:0005652 nuclear lamina(GO:0005652)
0.0 1.0 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.9 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.8 GO:0005905 clathrin-coated pit(GO:0005905)
0.2 0.7 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.0 0.7 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.7 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.7 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.0 0.6 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.4 GO:0033270 paranode region of axon(GO:0033270)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 21 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.2 GO:0045296 cadherin binding(GO:0045296)
0.0 4.0 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 2.3 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 1.8 GO:0070182 DNA polymerase binding(GO:0070182)
0.2 1.7 GO:0031419 cobalamin binding(GO:0031419)
0.3 1.6 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.1 1.6 GO:0001056 RNA polymerase III activity(GO:0001056)
0.1 1.3 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.3 1.0 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.1 0.9 GO:0050733 RS domain binding(GO:0050733)
0.0 0.9 GO:0015026 coreceptor activity(GO:0015026)
0.1 0.7 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.1 0.7 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.7 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.6 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 0.5 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 0.4 GO:0017084 glutamate 5-kinase activity(GO:0004349) glutamate-5-semialdehyde dehydrogenase activity(GO:0004350) delta1-pyrroline-5-carboxylate synthetase activity(GO:0017084) amino acid kinase activity(GO:0019202)
0.1 0.4 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.4 GO:0071889 14-3-3 protein binding(GO:0071889)

Gene overrepresentation in C2:CP category:

Showing 1 to 7 of 7 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.9 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.0 2.0 PID_BCR_5PATHWAY BCR signaling pathway
0.0 1.8 ST_FAS_SIGNALING_PATHWAY Fas Signaling Pathway
0.0 0.9 PID_CD8_TCR_PATHWAY TCR signaling in naïve CD8+ T cells
0.1 0.7 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.0 0.4 PID_ARF6_PATHWAY Arf6 signaling events
0.0 0.3 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 7 of 7 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.6 REACTOME_PROCESSIVE_SYNTHESIS_ON_THE_LAGGING_STRAND Genes involved in Processive synthesis on the lagging strand
0.1 1.6 REACTOME_RNA_POL_III_CHAIN_ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.1 0.7 REACTOME_OLFACTORY_SIGNALING_PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.6 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.6 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.5 REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.4 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)