Motif ID: Myod1
Z-value: 0.559
Transcription factors associated with Myod1:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Myod1 | ENSMUSG00000009471.3 | Myod1 |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 192 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.2 | 14.4 | GO:0061302 | smooth muscle cell-matrix adhesion(GO:0061302) |
| 0.9 | 9.4 | GO:0002315 | marginal zone B cell differentiation(GO:0002315) |
| 2.7 | 8.2 | GO:0001869 | regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869) |
| 0.6 | 6.0 | GO:0034983 | peptidyl-lysine deacetylation(GO:0034983) regulation of skeletal muscle fiber development(GO:0048742) |
| 1.4 | 5.8 | GO:0060032 | notochord regression(GO:0060032) |
| 0.2 | 4.7 | GO:0040034 | regulation of development, heterochronic(GO:0040034) |
| 0.7 | 4.4 | GO:0097473 | cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473) |
| 0.2 | 3.9 | GO:0038092 | nodal signaling pathway(GO:0038092) |
| 0.3 | 3.8 | GO:0009404 | toxin metabolic process(GO:0009404) |
| 0.3 | 3.7 | GO:0070886 | positive regulation of calcineurin-NFAT signaling cascade(GO:0070886) |
| 0.2 | 3.5 | GO:0010831 | positive regulation of myotube differentiation(GO:0010831) |
| 0.1 | 3.2 | GO:0051592 | response to calcium ion(GO:0051592) |
| 0.1 | 3.2 | GO:0006890 | retrograde vesicle-mediated transport, Golgi to ER(GO:0006890) |
| 1.0 | 3.0 | GO:0051464 | positive regulation of cortisol secretion(GO:0051464) |
| 0.2 | 3.0 | GO:0060159 | regulation of dopamine receptor signaling pathway(GO:0060159) |
| 0.7 | 2.9 | GO:0032289 | central nervous system myelin formation(GO:0032289) cardiac cell fate specification(GO:0060912) |
| 0.4 | 2.7 | GO:0006287 | base-excision repair, gap-filling(GO:0006287) |
| 0.0 | 2.7 | GO:0002377 | immunoglobulin production(GO:0002377) |
| 0.7 | 2.6 | GO:0010288 | response to lead ion(GO:0010288) |
| 0.4 | 2.5 | GO:0035948 | positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072366) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 86 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 14.9 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 0.2 | 9.1 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
| 0.1 | 8.6 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.1 | 6.0 | GO:0035097 | histone methyltransferase complex(GO:0035097) |
| 0.4 | 5.8 | GO:0097542 | ciliary tip(GO:0097542) |
| 0.1 | 5.4 | GO:0016459 | myosin complex(GO:0016459) |
| 0.0 | 4.7 | GO:0005923 | bicellular tight junction(GO:0005923) |
| 0.3 | 4.4 | GO:0032593 | insulin-responsive compartment(GO:0032593) |
| 0.0 | 4.0 | GO:0031012 | extracellular matrix(GO:0031012) |
| 0.1 | 3.3 | GO:0031985 | Golgi cisterna(GO:0031985) |
| 0.1 | 3.0 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
| 0.0 | 3.0 | GO:0031965 | nuclear membrane(GO:0031965) |
| 0.7 | 2.6 | GO:0097129 | cyclin D2-CDK4 complex(GO:0097129) |
| 0.8 | 2.5 | GO:0071149 | TEAD-2-YAP complex(GO:0071149) |
| 0.2 | 2.2 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) |
| 0.1 | 2.2 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
| 0.1 | 2.1 | GO:0005865 | striated muscle thin filament(GO:0005865) |
| 0.1 | 2.1 | GO:0002102 | podosome(GO:0002102) |
| 0.0 | 2.1 | GO:0032993 | protein-DNA complex(GO:0032993) |
| 0.1 | 2.0 | GO:0097038 | perinuclear endoplasmic reticulum(GO:0097038) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 126 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.6 | 14.4 | GO:0038062 | protein tyrosine kinase collagen receptor activity(GO:0038062) |
| 3.0 | 9.1 | GO:0033829 | O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829) |
| 0.5 | 9.1 | GO:0001848 | complement binding(GO:0001848) |
| 0.3 | 6.0 | GO:0031078 | histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) |
| 0.1 | 6.0 | GO:0005080 | protein kinase C binding(GO:0005080) |
| 0.0 | 4.5 | GO:0003714 | transcription corepressor activity(GO:0003714) |
| 0.1 | 4.4 | GO:0004693 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) |
| 0.1 | 4.1 | GO:0008307 | structural constituent of muscle(GO:0008307) |
| 0.1 | 3.9 | GO:0008146 | sulfotransferase activity(GO:0008146) |
| 1.3 | 3.8 | GO:0016715 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715) |
| 0.0 | 3.7 | GO:0001076 | transcription factor activity, RNA polymerase II transcription factor binding(GO:0001076) |
| 0.1 | 3.4 | GO:0070273 | phosphatidylinositol-4-phosphate binding(GO:0070273) |
| 0.1 | 3.4 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
| 0.7 | 3.0 | GO:0004966 | galanin receptor activity(GO:0004966) |
| 0.1 | 3.0 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
| 0.1 | 2.8 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
| 0.1 | 2.8 | GO:0017022 | myosin binding(GO:0017022) |
| 0.3 | 2.7 | GO:0051575 | 5'-deoxyribose-5-phosphate lyase activity(GO:0051575) |
| 0.1 | 2.6 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
| 0.0 | 2.6 | GO:0008081 | phosphoric diester hydrolase activity(GO:0008081) |
Gene overrepresentation in C2:CP category:
Showing 1 to 20 of 46 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 10.1 | NABA_ECM_REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.1 | 6.5 | PID_HDAC_CLASSI_PATHWAY | Signaling events mediated by HDAC Class I |
| 0.2 | 6.1 | PID_ECADHERIN_KERATINOCYTE_PATHWAY | E-cadherin signaling in keratinocytes |
| 0.2 | 6.1 | PID_HEDGEHOG_2PATHWAY | Signaling events mediated by the Hedgehog family |
| 0.1 | 4.5 | PID_HNF3A_PATHWAY | FOXA1 transcription factor network |
| 0.1 | 3.0 | PID_P38_MKK3_6PATHWAY | p38 MAPK signaling pathway |
| 0.1 | 2.8 | PID_IL2_STAT5_PATHWAY | IL2 signaling events mediated by STAT5 |
| 0.1 | 2.7 | PID_DNA_PK_PATHWAY | DNA-PK pathway in nonhomologous end joining |
| 0.2 | 2.6 | SA_REG_CASCADE_OF_CYCLIN_EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 0.1 | 2.4 | PID_ECADHERIN_STABILIZATION_PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
| 0.1 | 1.9 | PID_P38_MK2_PATHWAY | p38 signaling mediated by MAPKAP kinases |
| 0.0 | 1.9 | WNT_SIGNALING | Genes related to Wnt-mediated signal transduction |
| 0.0 | 1.7 | PID_AURORA_B_PATHWAY | Aurora B signaling |
| 0.0 | 1.7 | SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES | Genes related to the insulin receptor pathway |
| 0.0 | 1.7 | PID_RAC1_REG_PATHWAY | Regulation of RAC1 activity |
| 0.0 | 1.6 | NABA_SECRETED_FACTORS | Genes encoding secreted soluble factors |
| 0.0 | 1.5 | PID_CD8_TCR_PATHWAY | TCR signaling in naïve CD8+ T cells |
| 0.1 | 1.3 | PID_ECADHERIN_NASCENT_AJ_PATHWAY | E-cadherin signaling in the nascent adherens junction |
| 0.0 | 1.3 | PID_A6B1_A6B4_INTEGRIN_PATHWAY | a6b1 and a6b4 Integrin signaling |
| 0.0 | 1.2 | PID_FAK_PATHWAY | Signaling events mediated by focal adhesion kinase |
Gene overrepresentation in C2:CP:REACTOME category:
Showing 1 to 20 of 57 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 9.7 | REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI | Genes involved in Pre-NOTCH Processing in Golgi |
| 0.8 | 8.2 | REACTOME_INTRINSIC_PATHWAY | Genes involved in Intrinsic Pathway |
| 0.3 | 5.0 | REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GLP1 | Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1) |
| 0.1 | 5.0 | REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |
| 0.1 | 4.5 | REACTOME_G1_PHASE | Genes involved in G1 Phase |
| 0.3 | 4.4 | REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK | Genes involved in Negative regulation of the PI3K/AKT network |
| 0.2 | 4.3 | REACTOME_STRIATED_MUSCLE_CONTRACTION | Genes involved in Striated Muscle Contraction |
| 0.0 | 4.2 | REACTOME_G_ALPHA_I_SIGNALLING_EVENTS | Genes involved in G alpha (i) signalling events |
| 0.1 | 3.6 | REACTOME_TIGHT_JUNCTION_INTERACTIONS | Genes involved in Tight junction interactions |
| 0.1 | 3.6 | REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY | Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity |
| 0.1 | 3.2 | REACTOME_RNA_POL_III_TRANSCRIPTION_TERMINATION | Genes involved in RNA Polymerase III Transcription Termination |
| 0.1 | 3.2 | REACTOME_CHONDROITIN_SULFATE_DERMATAN_SULFATE_METABOLISM | Genes involved in Chondroitin sulfate/dermatan sulfate metabolism |
| 0.0 | 2.6 | REACTOME_NETRIN1_SIGNALING | Genes involved in Netrin-1 signaling |
| 0.1 | 2.5 | REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
| 0.3 | 2.1 | REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS | Genes involved in Elevation of cytosolic Ca2+ levels |
| 0.1 | 2.1 | REACTOME_PEROXISOMAL_LIPID_METABOLISM | Genes involved in Peroxisomal lipid metabolism |
| 0.1 | 1.8 | REACTOME_SIGNALING_BY_ROBO_RECEPTOR | Genes involved in Signaling by Robo receptor |
| 0.2 | 1.7 | REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.0 | 1.7 | REACTOME_RNA_POL_I_PROMOTER_OPENING | Genes involved in RNA Polymerase I Promoter Opening |
| 0.1 | 1.6 | REACTOME_MUSCLE_CONTRACTION | Genes involved in Muscle contraction |
