Motif ID: Nfat5

Z-value: 0.646


Transcription factors associated with Nfat5:

Gene SymbolEntrez IDGene Name
Nfat5 ENSMUSG00000003847.10 Nfat5

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nfat5mm10_v2_chr8_+_107293463_1072934830.084.8e-01Click!


Activity profile for motif Nfat5.

activity profile for motif Nfat5


Sorted Z-values histogram for motif Nfat5

Sorted Z-values for motif Nfat5



Network of associatons between targets according to the STRING database.



First level regulatory network of Nfat5

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_101377897 8.910 ENSMUST00000075994.6
 Pdzrn3
PDZ domain containing RING finger 3
chr14_-_101609033 7.142 ENSMUST00000161991.1
ENSMUST00000100340.3
 Tbc1d4

TBC1 domain family, member 4

chr4_-_82505749 4.688 ENSMUST00000107245.2
ENSMUST00000107246.1
 Nfib

nuclear factor I/B

chr10_-_95415484 4.685 ENSMUST00000172070.1
ENSMUST00000150432.1
 Socs2

suppressor of cytokine signaling 2

chr7_-_97417730 4.507 ENSMUST00000043077.7
 Thrsp
thyroid hormone responsive
chr4_-_82505707 4.146 ENSMUST00000107248.1
ENSMUST00000107247.1
 Nfib

nuclear factor I/B

chr10_-_95415283 4.059 ENSMUST00000119917.1
 Socs2
suppressor of cytokine signaling 2
chr5_-_104021919 4.053 ENSMUST00000031251.9
 Hsd17b11
hydroxysteroid (17-beta) dehydrogenase 11
chr4_-_138396438 3.355 ENSMUST00000105032.2
 Fam43b
family with sequence similarity 43, member B
chr5_-_104021799 3.071 ENSMUST00000119025.1
 Hsd17b11
hydroxysteroid (17-beta) dehydrogenase 11
chr15_-_98881255 3.054 ENSMUST00000024518.9
 Rhebl1
Ras homolog enriched in brain like 1
chr5_-_148392810 2.684 ENSMUST00000138257.1
 Slc7a1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr5_-_124354671 2.578 ENSMUST00000031341.4
 Cdk2ap1
CDK2 (cyclin-dependent kinase 2)-associated protein 1
chr2_+_68117713 2.570 ENSMUST00000112346.2
 B3galt1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr7_-_80402743 2.308 ENSMUST00000122232.1
 Furin
furin (paired basic amino acid cleaving enzyme)
chr14_+_17660956 2.185 ENSMUST00000022303.7
ENSMUST00000091471.4
 Thrb

thyroid hormone receptor beta

chr16_-_55838827 2.183 ENSMUST00000096026.2
ENSMUST00000036273.6
ENSMUST00000114457.1
 Nfkbiz


nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta


chr11_+_102836296 1.993 ENSMUST00000021302.8
ENSMUST00000107072.1
 Higd1b

HIG1 domain family, member 1B

chr7_+_99535652 1.907 ENSMUST00000032995.8
ENSMUST00000162404.1
 Arrb1

arrestin, beta 1

chr3_-_129755305 1.895 ENSMUST00000029653.2
 Egf
epidermal growth factor
chr9_-_29963112 1.865 ENSMUST00000075069.4
 Ntm
neurotrimin
chr11_-_88863717 1.839 ENSMUST00000107904.2
 Akap1
A kinase (PRKA) anchor protein 1
chr5_+_90772435 1.768 ENSMUST00000031320.6
 Pf4
platelet factor 4
chr6_+_120773633 1.746 ENSMUST00000112682.2
 Slc25a18
solute carrier family 25 (mitochondrial carrier), member 18
chr15_-_75894474 1.661 ENSMUST00000023237.6
 Naprt1
nicotinate phosphoribosyltransferase domain containing 1
chr19_-_5845471 1.615 ENSMUST00000174287.1
ENSMUST00000173672.1
 Neat1

nuclear paraspeckle assembly transcript 1 (non-protein coding)

chr10_-_78352212 1.557 ENSMUST00000146899.1
 Agpat3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr7_+_99535439 1.529 ENSMUST00000098266.2
ENSMUST00000179755.1
 Arrb1

arrestin, beta 1

chr5_+_139423151 1.520 ENSMUST00000066211.4
 Gper1
G protein-coupled estrogen receptor 1
chr5_-_69592311 1.462 ENSMUST00000031117.6
 Gnpda2
glucosamine-6-phosphate deaminase 2
chr2_-_30415389 1.453 ENSMUST00000142096.1
 Crat
carnitine acetyltransferase
chr10_-_62507737 1.452 ENSMUST00000020271.6
 Srgn
serglycin
chr6_-_58907120 1.405 ENSMUST00000059539.3
 Nap1l5
nucleosome assembly protein 1-like 5
chr10_-_78351690 1.358 ENSMUST00000166360.1
 Agpat3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr1_+_24678536 1.328 ENSMUST00000095062.3
 Lmbrd1
LMBR1 domain containing 1
chr10_-_78352053 1.307 ENSMUST00000105388.1
 Agpat3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr2_-_30415302 1.250 ENSMUST00000132981.2
ENSMUST00000129494.1
 Crat

carnitine acetyltransferase

chr15_-_38078842 1.206 ENSMUST00000110336.2
 Ubr5
ubiquitin protein ligase E3 component n-recognin 5
chr2_-_30415509 1.187 ENSMUST00000134120.1
ENSMUST00000102854.3
 Crat

carnitine acetyltransferase

chr10_+_21994666 1.164 ENSMUST00000020145.5
 Sgk1
serum/glucocorticoid regulated kinase 1
chr7_-_46958475 1.129 ENSMUST00000094398.4
 Uevld
UEV and lactate/malate dehyrogenase domains
chr12_-_86079019 1.124 ENSMUST00000003687.6
 Tgfb3
transforming growth factor, beta 3
chr6_-_144209471 1.119 ENSMUST00000038815.7
 Sox5
SRY-box containing gene 5
chr6_-_144209558 1.107 ENSMUST00000111749.1
ENSMUST00000170367.2
 Sox5

SRY-box containing gene 5

chr17_+_43389436 1.087 ENSMUST00000113599.1
 Gpr116
G protein-coupled receptor 116
chr6_-_144209448 1.076 ENSMUST00000077160.5
 Sox5
SRY-box containing gene 5
chr10_-_78351711 1.036 ENSMUST00000105390.1
 Agpat3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr18_+_36559972 1.036 ENSMUST00000134146.1
 Ankhd1
ankyrin repeat and KH domain containing 1
chr9_+_92457369 1.032 ENSMUST00000034941.7
 Plscr4
phospholipid scramblase 4
chr6_-_142964404 0.997 ENSMUST00000032421.3
 St8sia1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chr18_+_36560581 0.977 ENSMUST00000155329.2
 Ankhd1
ankyrin repeat and KH domain containing 1
chr8_-_46124146 0.964 ENSMUST00000170416.1
 Snx25
sorting nexin 25
chr7_+_6371364 0.888 ENSMUST00000086323.4
ENSMUST00000108559.2
 Zfp78

zinc finger protein 78

chr6_+_91684061 0.886 ENSMUST00000032185.7
 Slc6a6
solute carrier family 6 (neurotransmitter transporter, taurine), member 6
chr11_-_118401826 0.885 ENSMUST00000106290.3
ENSMUST00000043722.3
 Lgals3bp

lectin, galactoside-binding, soluble, 3 binding protein

chr7_-_126625676 0.864 ENSMUST00000032961.3
 Nupr1
nuclear protein transcription regulator 1
chr10_+_84622365 0.712 ENSMUST00000077175.5
 Polr3b
polymerase (RNA) III (DNA directed) polypeptide B
chr12_+_102948843 0.612 ENSMUST00000101099.5
 Unc79
unc-79 homolog (C. elegans)
chr18_-_43477764 0.599 ENSMUST00000057110.9
 Eif3j2
eukaryotic translation initiation factor 3, subunit J2
chr9_-_71771535 0.593 ENSMUST00000122065.1
ENSMUST00000121322.1
ENSMUST00000072899.2
 Cgnl1


cingulin-like 1


chr8_+_86745679 0.566 ENSMUST00000098532.2
 Gm10638
predicted gene 10638
chr3_-_69004565 0.545 ENSMUST00000169064.1
 Ift80
intraflagellar transport 80
chr14_-_55116935 0.543 ENSMUST00000022819.5
 Jph4
junctophilin 4
chr19_+_10525244 0.514 ENSMUST00000038379.3
 Cpsf7
cleavage and polyadenylation specific factor 7
chr15_+_5185700 0.502 ENSMUST00000081640.5
 Ttc33
tetratricopeptide repeat domain 33
chr10_+_21993890 0.485 ENSMUST00000092673.4
 Sgk1
serum/glucocorticoid regulated kinase 1
chr1_-_9944103 0.427 ENSMUST00000182498.1
ENSMUST00000182742.1
ENSMUST00000182580.1
 Snhg6


small nucleolar RNA host gene (non-protein coding) 6


chr15_-_52478228 0.420 ENSMUST00000081993.1
 Gm10020
predicted pseudogene 10020
chr7_+_46847128 0.406 ENSMUST00000005051.4
 Ldha
lactate dehydrogenase A
chr9_-_7835255 0.401 ENSMUST00000074246.6
 Birc2
baculoviral IAP repeat-containing 2
chr6_-_92183972 0.396 ENSMUST00000140438.1
 Mrps25
mitochondrial ribosomal protein S25
chr4_+_110397764 0.386 ENSMUST00000097920.2
ENSMUST00000080744.6
 Agbl4

ATP/GTP binding protein-like 4

chr10_+_4611971 0.367 ENSMUST00000105590.1
ENSMUST00000067086.7
 Esr1

estrogen receptor 1 (alpha)

chr19_-_10525201 0.362 ENSMUST00000025570.6
 Sdhaf2
succinate dehydrogenase complex assembly factor 2
chr17_+_91236787 0.352 ENSMUST00000057074.8
 Gm6741
predicted gene 6741
chr4_+_141444654 0.331 ENSMUST00000006377.6
 Zbtb17
zinc finger and BTB domain containing 17
chr17_+_87107621 0.315 ENSMUST00000041369.6
 Socs5
suppressor of cytokine signaling 5
chr7_-_81493725 0.246 ENSMUST00000119121.1
 Ap3b2
adaptor-related protein complex 3, beta 2 subunit
chr1_+_83159733 0.235 ENSMUST00000113436.1
ENSMUST00000065436.3
ENSMUST00000065403.6
 Daw1


dynein assembly factor with WDR repeat domains 1


chr14_-_16575456 0.224 ENSMUST00000063750.6
 Rarb
retinoic acid receptor, beta
chr14_+_8080315 0.203 ENSMUST00000023924.3
 Rpp14
ribonuclease P 14 subunit
chrX_+_139684980 0.189 ENSMUST00000096313.3
 Tbc1d8b
TBC1 domain family, member 8B
chr1_+_45981548 0.180 ENSMUST00000085632.2
 Rpl23a-ps1
ribosomal protein 23A, pseudogene 1
chrX_+_74429671 0.171 ENSMUST00000114127.1
ENSMUST00000064407.3
ENSMUST00000156707.1
 Ikbkg


inhibitor of kappaB kinase gamma


chr7_-_81493883 0.101 ENSMUST00000082090.7
 Ap3b2
adaptor-related protein complex 3, beta 2 subunit
chr13_+_73626886 0.095 ENSMUST00000022104.7
 Tert
telomerase reverse transcriptase
chr4_+_110397661 0.086 ENSMUST00000106589.2
ENSMUST00000106587.2
ENSMUST00000106591.1
ENSMUST00000106592.1
 Agbl4



ATP/GTP binding protein-like 4



chr2_+_176831140 0.053 ENSMUST00000122218.2
ENSMUST00000126726.1
 Gm14408

predicted gene 14408

chrX_-_155216444 0.029 ENSMUST00000026318.8
 Sat1
spermidine/spermine N1-acetyl transferase 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 8.8 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
1.8 7.1 GO:0006710 androgen catabolic process(GO:0006710)
0.8 7.1 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.7 2.2 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.7 2.6 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.6 2.3 GO:0090472 dibasic protein processing(GO:0090472)
0.6 3.4 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.6 3.9 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.5 1.5 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.5 1.9 GO:0007262 STAT protein import into nucleus(GO:0007262)
0.5 3.3 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.5 8.7 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.4 1.2 GO:1902915 negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.4 1.8 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347) negative regulation of cytolysis(GO:0045918)
0.3 2.6 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.2 1.8 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.2 2.7 GO:0015809 arginine transport(GO:0015809)
0.2 4.5 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866)
0.1 8.9 GO:0007528 neuromuscular junction development(GO:0007528)
0.1 0.4 GO:1902527 positive regulation of protein K48-linked ubiquitination(GO:1902524) positive regulation of protein monoubiquitination(GO:1902527)
0.1 0.4 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.1 0.5 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.1 1.6 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.1 0.9 GO:2000194 regulation of female gonad development(GO:2000194)
0.1 0.4 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.1 0.4 GO:0019659 fermentation(GO:0006113) lactate biosynthetic process from pyruvate(GO:0019244) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.1 0.3 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.1 1.5 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.1 1.6 GO:0030575 nuclear body organization(GO:0030575)
0.1 0.6 GO:0048149 behavioral response to ethanol(GO:0048149)
0.1 1.0 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1 2.6 GO:0060325 face morphogenesis(GO:0060325)
0.1 0.5 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.1 1.3 GO:0046325 negative regulation of glucose import(GO:0046325)
0.0 0.2 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.1 GO:1900369 negative regulation of RNA interference(GO:1900369) regulation of histone demethylase activity (H3-K4 specific)(GO:1904173)
0.0 5.3 GO:0008654 phospholipid biosynthetic process(GO:0008654)
0.0 0.9 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 3.2 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.0 1.0 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.7 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.2 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.3 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.9 GO:0010977 negative regulation of neuron projection development(GO:0010977)
0.0 1.4 GO:0006334 nucleosome assembly(GO:0006334)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 8.8 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.2 3.4 GO:0031143 pseudopodium(GO:0031143)
0.2 1.6 GO:0042382 paraspeckles(GO:0042382)
0.2 1.5 GO:0042629 mast cell granule(GO:0042629)
0.2 1.5 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 1.8 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
0.1 2.3 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.1 9.0 GO:0005811 lipid particle(GO:0005811)
0.1 0.5 GO:0030314 junctional membrane complex(GO:0030314)
0.1 8.9 GO:0031594 neuromuscular junction(GO:0031594)
0.1 0.4 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.1 1.3 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.6 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.7 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.4 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.4 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.3 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.5 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 3.9 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.2 GO:0030677 ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.0 2.2 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.2 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.5 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 3.3 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.0 1.1 GO:0030315 T-tubule(GO:0030315)
0.0 1.9 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.4 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) small ribosomal subunit(GO:0015935)
0.0 0.6 GO:0016459 myosin complex(GO:0016459)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 8.7 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
1.1 3.4 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
1.0 7.1 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
1.0 3.9 GO:0004092 carnitine O-acetyltransferase activity(GO:0004092)
0.6 2.6 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.4 2.2 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.4 1.8 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.3 2.7 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.3 1.9 GO:0030284 estrogen receptor activity(GO:0030284)
0.3 1.5 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.3 1.1 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.3 5.3 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.2 8.8 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.2 2.3 GO:0048406 nerve growth factor binding(GO:0048406)
0.2 1.6 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.2 1.3 GO:0031419 cobalamin binding(GO:0031419)
0.2 1.0 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 1.7 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.1 0.4 GO:0098770 FBXO family protein binding(GO:0098770)
0.1 1.8 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.1 1.0 GO:0042609 CD4 receptor binding(GO:0042609)
0.1 0.4 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 1.2 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 2.6 GO:0070182 DNA polymerase binding(GO:0070182)
0.1 1.9 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 1.0 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.1 0.2 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.1 0.9 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 7.3 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.9 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.7 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 8.9 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 1.5 GO:0005518 collagen binding(GO:0005518)
0.0 0.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.4 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.2 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.4 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 3.1 GO:0003924 GTPase activity(GO:0003924)
0.0 0.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.6 GO:0003743 translation initiation factor activity(GO:0003743)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 7.1 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.2 9.2 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.1 1.9 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.1 3.4 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events
0.1 8.7 PID_IL2_1PATHWAY IL2-mediated signaling events
0.1 1.8 PID_CXCR3_PATHWAY CXCR3-mediated signaling events
0.1 2.4 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.1 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.0 1.6 PID_PI3KCI_PATHWAY Class I PI3K signaling events
0.0 1.5 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 2.9 PID_P75_NTR_PATHWAY p75(NTR)-mediated signaling
0.0 2.6 ST_FAS_SIGNALING_PATHWAY Fas Signaling Pathway
0.0 1.8 PID_VEGFR1_2_PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.3 PID_MYC_PATHWAY C-MYC pathway
0.0 0.1 PID_IL2_PI3K_PATHWAY IL2 signaling events mediated by PI3K
0.0 0.3 PID_IL4_2PATHWAY IL4-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 9.5 REACTOME_RNA_POL_III_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.3 2.3 REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.3 1.8 REACTOME_COMMON_PATHWAY Genes involved in Common Pathway
0.3 8.7 REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING Genes involved in Growth hormone receptor signaling
0.2 5.3 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.1 3.9 REACTOME_PEROXISOMAL_LIPID_METABOLISM Genes involved in Peroxisomal lipid metabolism
0.1 1.9 REACTOME_SHC1_EVENTS_IN_EGFR_SIGNALING Genes involved in SHC1 events in EGFR signaling
0.1 3.6 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 3.4 REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 2.6 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 2.6 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.5 REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.4 REACTOME_PYRUVATE_METABOLISM Genes involved in Pyruvate metabolism
0.0 0.6 REACTOME_NOD1_2_SIGNALING_PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 1.8 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production