Motif ID: Nfatc2
Z-value: 1.623
Transcription factors associated with Nfatc2:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Nfatc2 | ENSMUSG00000027544.10 | Nfatc2 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Nfatc2 | mm10_v2_chr2_-_168590315_168590372 | 0.24 | 3.5e-02 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.8 | 19.0 | GO:0035063 | nuclear speck organization(GO:0035063) |
| 2.5 | 9.9 | GO:2000795 | negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795) |
| 1.7 | 1.7 | GO:0098923 | retrograde trans-synaptic signaling by soluble gas(GO:0098923) |
| 1.7 | 6.7 | GO:0090126 | protein complex assembly involved in synapse maturation(GO:0090126) |
| 1.4 | 11.6 | GO:0060164 | regulation of timing of neuron differentiation(GO:0060164) |
| 1.3 | 6.3 | GO:1903566 | positive regulation of protein localization to cilium(GO:1903566) |
| 1.2 | 4.7 | GO:2000211 | regulation of glutamate metabolic process(GO:2000211) |
| 1.1 | 4.3 | GO:0060486 | Clara cell differentiation(GO:0060486) |
| 1.1 | 6.4 | GO:1903056 | positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056) |
| 0.9 | 2.7 | GO:1900275 | negative regulation of phospholipase C activity(GO:1900275) |
| 0.9 | 4.4 | GO:0042636 | negative regulation of hair cycle(GO:0042636) progesterone secretion(GO:0042701) negative regulation of hair follicle development(GO:0051799) positive regulation of ovulation(GO:0060279) |
| 0.8 | 2.5 | GO:0002678 | positive regulation of chronic inflammatory response(GO:0002678) |
| 0.7 | 2.2 | GO:0002302 | CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302) |
| 0.7 | 3.7 | GO:1901843 | positive regulation of high voltage-gated calcium channel activity(GO:1901843) |
| 0.7 | 2.7 | GO:0072362 | regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072362) |
| 0.7 | 2.7 | GO:0072137 | condensed mesenchymal cell proliferation(GO:0072137) |
| 0.7 | 2.0 | GO:1901608 | dense core granule localization(GO:0032253) cellular response to isoquinoline alkaloid(GO:0071317) regulation of vesicle transport along microtubule(GO:1901608) dense core granule transport(GO:1901950) regulation of dense core granule transport(GO:1904809) positive regulation of dense core granule transport(GO:1904811) |
| 0.6 | 4.5 | GO:1901525 | negative regulation of macromitophagy(GO:1901525) regulation of mitophagy in response to mitochondrial depolarization(GO:1904923) |
| 0.6 | 2.5 | GO:0021564 | glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564) |
| 0.6 | 1.9 | GO:0090526 | regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526) |
| 0.6 | 3.1 | GO:0098735 | positive regulation of the force of heart contraction(GO:0098735) |
| 0.6 | 1.8 | GO:0002430 | complement receptor mediated signaling pathway(GO:0002430) GPI anchor release(GO:0006507) |
| 0.6 | 3.5 | GO:0051694 | pointed-end actin filament capping(GO:0051694) |
| 0.6 | 2.2 | GO:2000182 | regulation of progesterone biosynthetic process(GO:2000182) |
| 0.6 | 1.7 | GO:0038095 | positive regulation of mast cell cytokine production(GO:0032765) Fc-epsilon receptor signaling pathway(GO:0038095) |
| 0.5 | 3.2 | GO:0000160 | phosphorelay signal transduction system(GO:0000160) |
| 0.5 | 1.5 | GO:0036228 | protein targeting to nuclear inner membrane(GO:0036228) |
| 0.5 | 3.0 | GO:0032929 | negative regulation of superoxide anion generation(GO:0032929) |
| 0.5 | 1.5 | GO:0003221 | right ventricular cardiac muscle tissue morphogenesis(GO:0003221) |
| 0.5 | 2.5 | GO:0018076 | N-terminal peptidyl-lysine acetylation(GO:0018076) |
| 0.5 | 1.0 | GO:0060060 | post-embryonic retina morphogenesis in camera-type eye(GO:0060060) |
| 0.5 | 2.9 | GO:0071955 | recycling endosome to Golgi transport(GO:0071955) |
| 0.5 | 1.9 | GO:0051866 | general adaptation syndrome(GO:0051866) |
| 0.5 | 4.1 | GO:0050908 | detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962) |
| 0.4 | 2.2 | GO:0061086 | negative regulation of histone H3-K27 methylation(GO:0061086) |
| 0.4 | 1.3 | GO:0044028 | DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029) |
| 0.4 | 2.6 | GO:0035826 | rubidium ion transport(GO:0035826) cellular hypotonic response(GO:0071476) |
| 0.4 | 3.8 | GO:0098907 | protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371) regulation of SA node cell action potential(GO:0098907) |
| 0.4 | 1.3 | GO:0090425 | hepatocyte cell migration(GO:0002194) positive regulation of sarcomere organization(GO:0060298) pancreas morphogenesis(GO:0061113) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979) |
| 0.4 | 0.4 | GO:0048859 | formation of anatomical boundary(GO:0048859) |
| 0.4 | 1.2 | GO:0023016 | signal transduction by trans-phosphorylation(GO:0023016) |
| 0.4 | 1.2 | GO:2000620 | positive regulation of histone H4-K16 acetylation(GO:2000620) |
| 0.4 | 1.6 | GO:0099527 | postsynapse to nucleus signaling pathway(GO:0099527) |
| 0.4 | 4.3 | GO:2000766 | negative regulation of cytoplasmic translation(GO:2000766) |
| 0.4 | 2.3 | GO:0035469 | determination of pancreatic left/right asymmetry(GO:0035469) |
| 0.4 | 1.1 | GO:0034334 | adherens junction maintenance(GO:0034334) |
| 0.4 | 1.1 | GO:0070649 | meiotic chromosome movement towards spindle pole(GO:0016344) formin-nucleated actin cable assembly(GO:0070649) |
| 0.4 | 1.5 | GO:1903760 | regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760) regulation of potassium ion export across plasma membrane(GO:1903764) regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905024) |
| 0.4 | 1.1 | GO:0003345 | proepicardium cell migration involved in pericardium morphogenesis(GO:0003345) |
| 0.4 | 2.9 | GO:0061368 | maternal process involved in parturition(GO:0060137) behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368) |
| 0.4 | 1.1 | GO:1904339 | negative regulation of dopaminergic neuron differentiation(GO:1904339) |
| 0.4 | 0.7 | GO:0007228 | positive regulation of hh target transcription factor activity(GO:0007228) |
| 0.4 | 1.8 | GO:2000346 | negative regulation of hepatocyte proliferation(GO:2000346) |
| 0.3 | 2.4 | GO:0002674 | negative regulation of acute inflammatory response(GO:0002674) |
| 0.3 | 2.1 | GO:0034773 | histone H4-K20 trimethylation(GO:0034773) establishment of Sertoli cell barrier(GO:0097368) |
| 0.3 | 3.4 | GO:1901409 | positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409) |
| 0.3 | 1.0 | GO:0035694 | mitochondrial protein catabolic process(GO:0035694) |
| 0.3 | 3.4 | GO:1902570 | protein localization to nucleolus(GO:1902570) |
| 0.3 | 4.6 | GO:2001256 | regulation of store-operated calcium entry(GO:2001256) |
| 0.3 | 1.0 | GO:0043323 | positive regulation of natural killer cell degranulation(GO:0043323) |
| 0.3 | 1.0 | GO:0035585 | calcium-mediated signaling using extracellular calcium source(GO:0035585) |
| 0.3 | 3.1 | GO:0046541 | saliva secretion(GO:0046541) |
| 0.3 | 0.9 | GO:1902630 | regulation of membrane hyperpolarization(GO:1902630) |
| 0.3 | 2.2 | GO:2000253 | positive regulation of feeding behavior(GO:2000253) |
| 0.3 | 4.4 | GO:0048672 | positive regulation of collateral sprouting(GO:0048672) |
| 0.3 | 0.9 | GO:0097401 | synaptic vesicle lumen acidification(GO:0097401) |
| 0.3 | 0.9 | GO:0070428 | regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428) regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070432) |
| 0.3 | 1.5 | GO:1900748 | positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748) |
| 0.3 | 1.4 | GO:0007256 | activation of JNKK activity(GO:0007256) |
| 0.3 | 1.2 | GO:0090273 | regulation of somatostatin secretion(GO:0090273) |
| 0.3 | 11.8 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
| 0.3 | 1.7 | GO:0016188 | synaptic vesicle maturation(GO:0016188) |
| 0.3 | 2.2 | GO:0006477 | protein sulfation(GO:0006477) |
| 0.3 | 1.1 | GO:0009405 | pathogenesis(GO:0009405) |
| 0.3 | 2.5 | GO:0035887 | aortic smooth muscle cell differentiation(GO:0035887) |
| 0.3 | 2.4 | GO:0007221 | positive regulation of transcription of Notch receptor target(GO:0007221) |
| 0.3 | 2.1 | GO:0014816 | skeletal muscle satellite cell differentiation(GO:0014816) |
| 0.3 | 0.8 | GO:0015882 | L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904) |
| 0.3 | 1.0 | GO:0033326 | cerebrospinal fluid secretion(GO:0033326) |
| 0.3 | 0.8 | GO:1903896 | positive regulation of IRE1-mediated unfolded protein response(GO:1903896) |
| 0.2 | 2.0 | GO:0018026 | peptidyl-lysine monomethylation(GO:0018026) |
| 0.2 | 4.5 | GO:0007194 | negative regulation of adenylate cyclase activity(GO:0007194) |
| 0.2 | 3.4 | GO:0034472 | snRNA 3'-end processing(GO:0034472) |
| 0.2 | 2.2 | GO:0050957 | equilibrioception(GO:0050957) |
| 0.2 | 1.0 | GO:0014846 | esophagus smooth muscle contraction(GO:0014846) |
| 0.2 | 1.9 | GO:0071557 | histone H3-K27 demethylation(GO:0071557) |
| 0.2 | 0.7 | GO:0002842 | T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) positive regulation of T cell mediated immune response to tumor cell(GO:0002842) protein import into mitochondrial intermembrane space(GO:0045041) |
| 0.2 | 0.9 | GO:1901668 | regulation of superoxide dismutase activity(GO:1901668) |
| 0.2 | 1.4 | GO:0090070 | positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234) |
| 0.2 | 5.7 | GO:0032011 | ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012) |
| 0.2 | 0.9 | GO:0099566 | regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566) |
| 0.2 | 1.3 | GO:0060017 | parathyroid gland development(GO:0060017) |
| 0.2 | 1.1 | GO:0043267 | negative regulation of potassium ion transport(GO:0043267) |
| 0.2 | 1.1 | GO:1903756 | regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758) |
| 0.2 | 1.0 | GO:1902510 | regulation of apoptotic DNA fragmentation(GO:1902510) |
| 0.2 | 0.8 | GO:0033140 | negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140) |
| 0.2 | 2.2 | GO:0042118 | endothelial cell activation(GO:0042118) |
| 0.2 | 0.8 | GO:0097118 | neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118) |
| 0.2 | 0.8 | GO:0006203 | dGTP catabolic process(GO:0006203) dATP catabolic process(GO:0046061) |
| 0.2 | 2.8 | GO:0035563 | positive regulation of chromatin binding(GO:0035563) |
| 0.2 | 1.4 | GO:2000124 | regulation of endocannabinoid signaling pathway(GO:2000124) |
| 0.2 | 2.8 | GO:1900119 | positive regulation of execution phase of apoptosis(GO:1900119) |
| 0.2 | 3.1 | GO:0000083 | regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083) |
| 0.2 | 0.8 | GO:0070562 | regulation of vitamin D receptor signaling pathway(GO:0070562) |
| 0.2 | 0.6 | GO:1900149 | positive regulation of Schwann cell migration(GO:1900149) |
| 0.2 | 1.1 | GO:0002051 | osteoblast fate commitment(GO:0002051) |
| 0.2 | 1.3 | GO:1990573 | potassium ion import across plasma membrane(GO:1990573) |
| 0.2 | 2.1 | GO:0060501 | positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501) |
| 0.2 | 1.9 | GO:0033148 | positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148) |
| 0.2 | 0.9 | GO:0033499 | galactose catabolic process via UDP-galactose(GO:0033499) |
| 0.2 | 0.6 | GO:2000393 | negative regulation of lamellipodium morphogenesis(GO:2000393) |
| 0.2 | 1.7 | GO:0016180 | snRNA processing(GO:0016180) |
| 0.2 | 2.0 | GO:0010839 | negative regulation of keratinocyte proliferation(GO:0010839) |
| 0.2 | 0.9 | GO:1902995 | apolipoprotein A-I-mediated signaling pathway(GO:0038027) negative regulation of amyloid precursor protein biosynthetic process(GO:0042985) regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995) positive regulation of apoptotic cell clearance(GO:2000427) |
| 0.2 | 1.8 | GO:0090394 | negative regulation of excitatory postsynaptic potential(GO:0090394) |
| 0.2 | 0.9 | GO:0017085 | response to insecticide(GO:0017085) |
| 0.2 | 0.9 | GO:0031022 | nuclear migration along microfilament(GO:0031022) |
| 0.2 | 2.1 | GO:1900383 | regulation of synaptic plasticity by receptor localization to synapse(GO:1900383) |
| 0.2 | 1.6 | GO:0070601 | centromeric sister chromatid cohesion(GO:0070601) |
| 0.2 | 1.0 | GO:0090383 | phagosome acidification(GO:0090383) |
| 0.2 | 0.5 | GO:0002946 | tRNA C5-cytosine methylation(GO:0002946) |
| 0.2 | 0.5 | GO:0042984 | amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984) |
| 0.2 | 1.7 | GO:0006002 | fructose 6-phosphate metabolic process(GO:0006002) |
| 0.2 | 1.0 | GO:0072318 | clathrin coat disassembly(GO:0072318) |
| 0.2 | 2.1 | GO:0060693 | regulation of branching involved in salivary gland morphogenesis(GO:0060693) |
| 0.2 | 2.5 | GO:0021902 | commitment of neuronal cell to specific neuron type in forebrain(GO:0021902) |
| 0.2 | 4.2 | GO:0045494 | photoreceptor cell maintenance(GO:0045494) |
| 0.2 | 0.8 | GO:0035754 | B cell chemotaxis(GO:0035754) |
| 0.2 | 0.5 | GO:0006106 | fumarate metabolic process(GO:0006106) aspartate biosynthetic process(GO:0006532) aspartate catabolic process(GO:0006533) alditol biosynthetic process(GO:0019401) |
| 0.2 | 3.0 | GO:0035235 | ionotropic glutamate receptor signaling pathway(GO:0035235) |
| 0.2 | 0.9 | GO:0002553 | histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553) |
| 0.2 | 1.7 | GO:0006488 | dolichol-linked oligosaccharide biosynthetic process(GO:0006488) |
| 0.2 | 0.6 | GO:0046655 | glycine biosynthetic process(GO:0006545) folic acid metabolic process(GO:0046655) |
| 0.2 | 1.8 | GO:0072658 | maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) |
| 0.2 | 1.4 | GO:0035721 | intraciliary retrograde transport(GO:0035721) |
| 0.2 | 1.1 | GO:0021869 | forebrain ventricular zone progenitor cell division(GO:0021869) |
| 0.1 | 1.2 | GO:0086023 | adrenergic receptor signaling pathway involved in heart process(GO:0086023) |
| 0.1 | 0.7 | GO:1903527 | positive regulation of membrane tubulation(GO:1903527) |
| 0.1 | 1.1 | GO:0061158 | 3'-UTR-mediated mRNA destabilization(GO:0061158) |
| 0.1 | 1.0 | GO:0097105 | presynaptic membrane assembly(GO:0097105) |
| 0.1 | 1.4 | GO:0070940 | dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940) |
| 0.1 | 0.9 | GO:0089700 | protein kinase D signaling(GO:0089700) |
| 0.1 | 1.2 | GO:0006682 | galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) |
| 0.1 | 0.9 | GO:1904627 | response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628) |
| 0.1 | 0.7 | GO:0042532 | negative regulation of tyrosine phosphorylation of STAT protein(GO:0042532) |
| 0.1 | 0.3 | GO:1904245 | regulation of polynucleotide adenylyltransferase activity(GO:1904245) |
| 0.1 | 1.0 | GO:0021785 | branchiomotor neuron axon guidance(GO:0021785) |
| 0.1 | 2.0 | GO:0035641 | locomotory exploration behavior(GO:0035641) |
| 0.1 | 2.0 | GO:2000251 | positive regulation of actin cytoskeleton reorganization(GO:2000251) |
| 0.1 | 1.1 | GO:2000467 | positive regulation of glycogen (starch) synthase activity(GO:2000467) |
| 0.1 | 2.6 | GO:0008090 | retrograde axonal transport(GO:0008090) |
| 0.1 | 1.4 | GO:0072189 | ureter development(GO:0072189) |
| 0.1 | 0.4 | GO:0019046 | release from viral latency(GO:0019046) |
| 0.1 | 0.7 | GO:0030643 | cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502) |
| 0.1 | 0.3 | GO:0070309 | lens fiber cell morphogenesis(GO:0070309) |
| 0.1 | 0.5 | GO:0046874 | quinolinate metabolic process(GO:0046874) |
| 0.1 | 0.5 | GO:0031642 | negative regulation of myelination(GO:0031642) |
| 0.1 | 4.1 | GO:0061512 | protein localization to cilium(GO:0061512) |
| 0.1 | 1.3 | GO:0060670 | branching involved in labyrinthine layer morphogenesis(GO:0060670) |
| 0.1 | 0.6 | GO:2000270 | negative regulation of fibroblast apoptotic process(GO:2000270) |
| 0.1 | 0.5 | GO:0097119 | postsynaptic density protein 95 clustering(GO:0097119) |
| 0.1 | 0.8 | GO:0097151 | positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828) |
| 0.1 | 0.5 | GO:0048852 | diencephalon morphogenesis(GO:0048852) |
| 0.1 | 0.4 | GO:0035521 | monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522) |
| 0.1 | 1.8 | GO:0031100 | organ regeneration(GO:0031100) |
| 0.1 | 1.3 | GO:0070842 | aggresome assembly(GO:0070842) |
| 0.1 | 0.4 | GO:0035989 | tendon development(GO:0035989) |
| 0.1 | 1.4 | GO:0009950 | dorsal/ventral axis specification(GO:0009950) |
| 0.1 | 1.7 | GO:0061157 | mRNA destabilization(GO:0061157) |
| 0.1 | 0.2 | GO:0051933 | amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935) |
| 0.1 | 0.4 | GO:0010510 | regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) |
| 0.1 | 2.3 | GO:2000369 | regulation of clathrin-mediated endocytosis(GO:2000369) |
| 0.1 | 0.2 | GO:1903054 | negative regulation of extracellular matrix organization(GO:1903054) |
| 0.1 | 0.9 | GO:0042760 | very long-chain fatty acid catabolic process(GO:0042760) |
| 0.1 | 1.1 | GO:0000183 | chromatin silencing at rDNA(GO:0000183) |
| 0.1 | 0.9 | GO:2000051 | negative regulation of non-canonical Wnt signaling pathway(GO:2000051) |
| 0.1 | 1.0 | GO:0090557 | establishment of endothelial intestinal barrier(GO:0090557) |
| 0.1 | 0.7 | GO:0035542 | regulation of SNARE complex assembly(GO:0035542) |
| 0.1 | 0.7 | GO:0071802 | negative regulation of podosome assembly(GO:0071802) |
| 0.1 | 0.5 | GO:2000741 | positive regulation of mesenchymal stem cell differentiation(GO:2000741) |
| 0.1 | 0.4 | GO:0035188 | blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684) |
| 0.1 | 0.5 | GO:0060050 | positive regulation of protein glycosylation(GO:0060050) spindle assembly involved in meiosis(GO:0090306) |
| 0.1 | 2.1 | GO:0010800 | positive regulation of peptidyl-threonine phosphorylation(GO:0010800) |
| 0.1 | 0.4 | GO:0019065 | receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509) |
| 0.1 | 0.4 | GO:2000807 | regulation of synaptic vesicle clustering(GO:2000807) |
| 0.1 | 1.7 | GO:0002091 | negative regulation of receptor internalization(GO:0002091) |
| 0.1 | 0.5 | GO:1903690 | negative regulation of wound healing, spreading of epidermal cells(GO:1903690) |
| 0.1 | 0.5 | GO:0071787 | endoplasmic reticulum tubular network assembly(GO:0071787) |
| 0.1 | 0.7 | GO:0036123 | histone H3-K9 dimethylation(GO:0036123) |
| 0.1 | 0.2 | GO:0031161 | phosphatidylinositol catabolic process(GO:0031161) |
| 0.1 | 0.7 | GO:0014029 | neural crest formation(GO:0014029) |
| 0.1 | 1.0 | GO:1901898 | negative regulation of relaxation of cardiac muscle(GO:1901898) |
| 0.1 | 1.2 | GO:0046069 | cGMP catabolic process(GO:0046069) |
| 0.1 | 0.2 | GO:0006436 | tryptophanyl-tRNA aminoacylation(GO:0006436) |
| 0.1 | 0.6 | GO:0032308 | positive regulation of prostaglandin secretion(GO:0032308) |
| 0.1 | 0.2 | GO:0045004 | DNA replication proofreading(GO:0045004) |
| 0.1 | 1.1 | GO:0051639 | actin filament network formation(GO:0051639) |
| 0.1 | 0.4 | GO:0051013 | microtubule severing(GO:0051013) |
| 0.1 | 1.3 | GO:0007097 | nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023) |
| 0.1 | 0.4 | GO:0060334 | regulation of interferon-gamma-mediated signaling pathway(GO:0060334) |
| 0.1 | 0.4 | GO:2000643 | positive regulation of early endosome to late endosome transport(GO:2000643) |
| 0.1 | 0.7 | GO:2000651 | positive regulation of sodium ion transmembrane transporter activity(GO:2000651) |
| 0.1 | 1.7 | GO:0007608 | sensory perception of smell(GO:0007608) |
| 0.1 | 1.2 | GO:0060252 | positive regulation of glial cell proliferation(GO:0060252) |
| 0.1 | 0.7 | GO:0036158 | outer dynein arm assembly(GO:0036158) |
| 0.1 | 2.6 | GO:0003301 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
| 0.1 | 0.5 | GO:0032793 | positive regulation of CREB transcription factor activity(GO:0032793) |
| 0.1 | 0.4 | GO:0048664 | neuron fate determination(GO:0048664) |
| 0.1 | 0.3 | GO:0042138 | meiotic DNA double-strand break formation(GO:0042138) |
| 0.1 | 0.2 | GO:0071918 | urea transmembrane transport(GO:0071918) |
| 0.1 | 2.1 | GO:0010591 | regulation of lamellipodium assembly(GO:0010591) |
| 0.1 | 0.5 | GO:0070874 | negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874) |
| 0.1 | 0.6 | GO:0019368 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
| 0.1 | 1.6 | GO:0015991 | ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662) |
| 0.1 | 0.8 | GO:0005980 | polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247) |
| 0.1 | 0.7 | GO:0000479 | endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479) |
| 0.1 | 0.5 | GO:0002176 | male germ cell proliferation(GO:0002176) |
| 0.1 | 0.6 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
| 0.1 | 0.2 | GO:0007128 | meiotic prophase I(GO:0007128) prophase(GO:0051324) |
| 0.1 | 3.0 | GO:0043488 | regulation of mRNA stability(GO:0043488) |
| 0.1 | 0.3 | GO:0006868 | glutamine transport(GO:0006868) |
| 0.1 | 0.4 | GO:0046477 | glycosylceramide catabolic process(GO:0046477) |
| 0.0 | 1.0 | GO:0000460 | maturation of 5.8S rRNA(GO:0000460) |
| 0.0 | 5.1 | GO:0007030 | Golgi organization(GO:0007030) |
| 0.0 | 0.5 | GO:0051315 | attachment of mitotic spindle microtubules to kinetochore(GO:0051315) |
| 0.0 | 0.5 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
| 0.0 | 0.3 | GO:0071481 | cellular response to X-ray(GO:0071481) |
| 0.0 | 0.3 | GO:0035331 | negative regulation of hippo signaling(GO:0035331) |
| 0.0 | 2.6 | GO:0000245 | spliceosomal complex assembly(GO:0000245) |
| 0.0 | 0.3 | GO:0003431 | growth plate cartilage chondrocyte development(GO:0003431) |
| 0.0 | 0.7 | GO:0001886 | endothelial cell morphogenesis(GO:0001886) |
| 0.0 | 0.1 | GO:0006083 | acetate metabolic process(GO:0006083) |
| 0.0 | 0.3 | GO:1904217 | regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222) |
| 0.0 | 1.8 | GO:0001658 | branching involved in ureteric bud morphogenesis(GO:0001658) |
| 0.0 | 0.7 | GO:0015701 | bicarbonate transport(GO:0015701) |
| 0.0 | 0.6 | GO:0010669 | epithelial structure maintenance(GO:0010669) |
| 0.0 | 0.9 | GO:0071108 | protein K48-linked deubiquitination(GO:0071108) |
| 0.0 | 0.7 | GO:0045475 | locomotor rhythm(GO:0045475) |
| 0.0 | 0.6 | GO:0033539 | fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539) |
| 0.0 | 1.0 | GO:1901998 | toxin transport(GO:1901998) |
| 0.0 | 2.7 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
| 0.0 | 1.7 | GO:0043044 | ATP-dependent chromatin remodeling(GO:0043044) |
| 0.0 | 0.1 | GO:0021943 | formation of radial glial scaffolds(GO:0021943) |
| 0.0 | 0.1 | GO:0034380 | high-density lipoprotein particle assembly(GO:0034380) |
| 0.0 | 0.5 | GO:0006622 | protein targeting to lysosome(GO:0006622) |
| 0.0 | 4.1 | GO:0071805 | potassium ion transmembrane transport(GO:0071805) |
| 0.0 | 1.0 | GO:0009988 | cell-cell recognition(GO:0009988) |
| 0.0 | 0.4 | GO:0000712 | resolution of meiotic recombination intermediates(GO:0000712) |
| 0.0 | 1.0 | GO:0007338 | single fertilization(GO:0007338) |
| 0.0 | 0.5 | GO:2000042 | negative regulation of double-strand break repair via homologous recombination(GO:2000042) |
| 0.0 | 1.3 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
| 0.0 | 1.7 | GO:0001510 | RNA methylation(GO:0001510) |
| 0.0 | 0.1 | GO:1900272 | negative regulation of long-term synaptic potentiation(GO:1900272) |
| 0.0 | 0.2 | GO:0030157 | pancreatic juice secretion(GO:0030157) |
| 0.0 | 0.1 | GO:0002101 | tRNA wobble cytosine modification(GO:0002101) |
| 0.0 | 0.3 | GO:0033572 | transferrin transport(GO:0033572) |
| 0.0 | 0.5 | GO:0071218 | cellular response to misfolded protein(GO:0071218) |
| 0.0 | 0.1 | GO:0015788 | UDP-N-acetylglucosamine transport(GO:0015788) |
| 0.0 | 0.1 | GO:0034316 | negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316) |
| 0.0 | 0.4 | GO:0051894 | positive regulation of focal adhesion assembly(GO:0051894) |
| 0.0 | 0.2 | GO:0072395 | signal transduction involved in cell cycle checkpoint(GO:0072395) signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in DNA damage checkpoint(GO:0072422) |
| 0.0 | 0.1 | GO:0015808 | L-alanine transport(GO:0015808) |
| 0.0 | 0.2 | GO:0051382 | kinetochore assembly(GO:0051382) |
| 0.0 | 0.9 | GO:0046888 | negative regulation of hormone secretion(GO:0046888) |
| 0.0 | 0.1 | GO:0030091 | protein repair(GO:0030091) |
| 0.0 | 0.2 | GO:1901621 | negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621) |
| 0.0 | 0.3 | GO:0007638 | mechanosensory behavior(GO:0007638) |
| 0.0 | 0.0 | GO:0002489 | antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489) |
| 0.0 | 0.2 | GO:0001967 | suckling behavior(GO:0001967) |
| 0.0 | 0.3 | GO:0019730 | antimicrobial humoral response(GO:0019730) |
| 0.0 | 0.1 | GO:0003062 | regulation of heart rate by chemical signal(GO:0003062) positive regulation of heart rate by epinephrine(GO:0003065) |
| 0.0 | 0.1 | GO:0016480 | negative regulation of transcription from RNA polymerase III promoter(GO:0016480) |
| 0.0 | 0.2 | GO:0032456 | endocytic recycling(GO:0032456) |
| 0.0 | 0.4 | GO:0090224 | regulation of mitotic spindle organization(GO:0060236) regulation of spindle organization(GO:0090224) |
| 0.0 | 0.1 | GO:0019227 | neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870) |
| 0.0 | 0.2 | GO:0071378 | growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378) |
| 0.0 | 0.4 | GO:0046326 | positive regulation of glucose import(GO:0046326) |
| 0.0 | 0.3 | GO:0051973 | positive regulation of telomerase activity(GO:0051973) |
| 0.0 | 0.3 | GO:0000060 | protein import into nucleus, translocation(GO:0000060) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.5 | 4.4 | GO:0043512 | inhibin A complex(GO:0043512) |
| 1.1 | 4.5 | GO:0044307 | dendritic branch(GO:0044307) |
| 0.8 | 6.9 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
| 0.7 | 2.6 | GO:0031673 | H zone(GO:0031673) |
| 0.6 | 4.7 | GO:0034750 | Scrib-APC-beta-catenin complex(GO:0034750) |
| 0.5 | 2.6 | GO:0002193 | MAML1-RBP-Jkappa- ICN1 complex(GO:0002193) |
| 0.5 | 1.8 | GO:0008623 | CHRAC(GO:0008623) |
| 0.5 | 1.8 | GO:0016012 | sarcoglycan complex(GO:0016012) |
| 0.4 | 1.3 | GO:0005943 | phosphatidylinositol 3-kinase complex, class IA(GO:0005943) |
| 0.4 | 1.7 | GO:0005945 | 6-phosphofructokinase complex(GO:0005945) |
| 0.4 | 2.5 | GO:0097504 | Gemini of coiled bodies(GO:0097504) |
| 0.4 | 8.4 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
| 0.4 | 1.2 | GO:0005899 | insulin receptor complex(GO:0005899) |
| 0.4 | 1.8 | GO:1990462 | omegasome(GO:1990462) |
| 0.3 | 2.7 | GO:0033648 | host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648) |
| 0.3 | 5.1 | GO:0032039 | integrator complex(GO:0032039) |
| 0.3 | 1.5 | GO:0044611 | nuclear pore inner ring(GO:0044611) |
| 0.3 | 2.9 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
| 0.3 | 2.8 | GO:0071439 | clathrin complex(GO:0071439) |
| 0.3 | 3.1 | GO:0008024 | cyclin/CDK positive transcription elongation factor complex(GO:0008024) |
| 0.3 | 2.2 | GO:0097433 | dense body(GO:0097433) |
| 0.3 | 2.4 | GO:0033180 | proton-transporting V-type ATPase, V1 domain(GO:0033180) |
| 0.3 | 12.7 | GO:0043034 | costamere(GO:0043034) |
| 0.2 | 4.2 | GO:0098839 | postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634) |
| 0.2 | 1.0 | GO:0031095 | platelet dense tubular network membrane(GO:0031095) |
| 0.2 | 4.3 | GO:1990124 | messenger ribonucleoprotein complex(GO:1990124) |
| 0.2 | 5.6 | GO:0071565 | nBAF complex(GO:0071565) |
| 0.2 | 2.0 | GO:0016600 | flotillin complex(GO:0016600) |
| 0.2 | 1.5 | GO:0097025 | MPP7-DLG1-LIN7 complex(GO:0097025) |
| 0.2 | 7.2 | GO:0032809 | neuronal cell body membrane(GO:0032809) |
| 0.2 | 3.0 | GO:0042788 | polysomal ribosome(GO:0042788) |
| 0.2 | 2.0 | GO:0030877 | beta-catenin destruction complex(GO:0030877) |
| 0.2 | 0.8 | GO:0005726 | perichromatin fibrils(GO:0005726) |
| 0.2 | 1.6 | GO:0031415 | NatA complex(GO:0031415) |
| 0.2 | 3.1 | GO:0036038 | MKS complex(GO:0036038) |
| 0.2 | 1.1 | GO:0071012 | catalytic step 1 spliceosome(GO:0071012) |
| 0.2 | 0.6 | GO:0045251 | mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251) |
| 0.1 | 0.9 | GO:0032591 | dendritic spine membrane(GO:0032591) |
| 0.1 | 1.7 | GO:0017146 | NMDA selective glutamate receptor complex(GO:0017146) |
| 0.1 | 2.1 | GO:0035145 | exon-exon junction complex(GO:0035145) |
| 0.1 | 2.7 | GO:0016580 | Sin3 complex(GO:0016580) |
| 0.1 | 0.5 | GO:0030981 | cortical microtubule cytoskeleton(GO:0030981) |
| 0.1 | 0.5 | GO:0043293 | apoptosome(GO:0043293) |
| 0.1 | 1.4 | GO:0061700 | GATOR2 complex(GO:0061700) |
| 0.1 | 1.7 | GO:0043194 | axon initial segment(GO:0043194) |
| 0.1 | 0.7 | GO:0046696 | lipopolysaccharide receptor complex(GO:0046696) |
| 0.1 | 1.5 | GO:1990635 | proximal dendrite(GO:1990635) |
| 0.1 | 1.1 | GO:0071141 | SMAD protein complex(GO:0071141) |
| 0.1 | 1.2 | GO:0070545 | PeBoW complex(GO:0070545) |
| 0.1 | 0.9 | GO:0034993 | microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993) |
| 0.1 | 1.6 | GO:0042405 | nuclear inclusion body(GO:0042405) |
| 0.1 | 1.6 | GO:0030122 | AP-2 adaptor complex(GO:0030122) |
| 0.1 | 1.9 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
| 0.1 | 0.3 | GO:0044753 | amphisome(GO:0044753) |
| 0.1 | 0.9 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
| 0.1 | 1.8 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
| 0.1 | 2.4 | GO:0060077 | inhibitory synapse(GO:0060077) |
| 0.1 | 1.4 | GO:0043196 | varicosity(GO:0043196) |
| 0.1 | 0.4 | GO:0097447 | dendritic tree(GO:0097447) |
| 0.1 | 0.5 | GO:0031313 | extrinsic component of endosome membrane(GO:0031313) |
| 0.1 | 1.3 | GO:0017119 | Golgi transport complex(GO:0017119) |
| 0.1 | 0.3 | GO:0097129 | cyclin D2-CDK4 complex(GO:0097129) |
| 0.1 | 4.9 | GO:0014704 | intercalated disc(GO:0014704) |
| 0.1 | 1.1 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) |
| 0.1 | 1.1 | GO:0016589 | NURF complex(GO:0016589) |
| 0.1 | 1.7 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
| 0.1 | 0.7 | GO:0036157 | outer dynein arm(GO:0036157) |
| 0.1 | 0.6 | GO:0030688 | preribosome, small subunit precursor(GO:0030688) |
| 0.1 | 0.2 | GO:0008622 | epsilon DNA polymerase complex(GO:0008622) |
| 0.1 | 0.7 | GO:0002177 | manchette(GO:0002177) |
| 0.1 | 1.1 | GO:0005666 | DNA-directed RNA polymerase III complex(GO:0005666) |
| 0.1 | 0.6 | GO:0060091 | kinocilium(GO:0060091) |
| 0.1 | 2.2 | GO:0097440 | apical dendrite(GO:0097440) |
| 0.1 | 0.3 | GO:0001652 | granular component(GO:0001652) |
| 0.1 | 0.4 | GO:0005818 | aster(GO:0005818) |
| 0.1 | 0.2 | GO:0000801 | central element(GO:0000801) |
| 0.1 | 0.4 | GO:0072357 | PTW/PP1 phosphatase complex(GO:0072357) |
| 0.1 | 6.5 | GO:0005814 | centriole(GO:0005814) |
| 0.1 | 0.4 | GO:0033256 | I-kappaB/NF-kappaB complex(GO:0033256) |
| 0.1 | 2.4 | GO:0032420 | stereocilium(GO:0032420) |
| 0.1 | 0.5 | GO:0000974 | Prp19 complex(GO:0000974) |
| 0.1 | 1.6 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
| 0.1 | 0.3 | GO:1990712 | HFE-transferrin receptor complex(GO:1990712) |
| 0.1 | 18.5 | GO:0060076 | excitatory synapse(GO:0060076) |
| 0.1 | 1.2 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
| 0.1 | 0.5 | GO:0005850 | eukaryotic translation initiation factor 2 complex(GO:0005850) |
| 0.1 | 0.8 | GO:0033655 | host cell cytoplasm(GO:0030430) host intracellular part(GO:0033646) host cell cytoplasm part(GO:0033655) intracellular region of host(GO:0043656) |
| 0.1 | 0.9 | GO:0001891 | phagocytic cup(GO:0001891) |
| 0.1 | 1.9 | GO:0034704 | calcium channel complex(GO:0034704) |
| 0.0 | 0.2 | GO:1990745 | EARP complex(GO:1990745) |
| 0.0 | 0.8 | GO:0071004 | U2-type prespliceosome(GO:0071004) |
| 0.0 | 2.4 | GO:0097610 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
| 0.0 | 0.4 | GO:0034464 | BBSome(GO:0034464) |
| 0.0 | 4.1 | GO:0042641 | actomyosin(GO:0042641) |
| 0.0 | 7.6 | GO:0044798 | nuclear transcription factor complex(GO:0044798) |
| 0.0 | 0.9 | GO:0030992 | intraciliary transport particle B(GO:0030992) |
| 0.0 | 2.8 | GO:0005930 | axoneme(GO:0005930) |
| 0.0 | 13.9 | GO:0016607 | nuclear speck(GO:0016607) |
| 0.0 | 0.9 | GO:0005689 | U12-type spliceosomal complex(GO:0005689) |
| 0.0 | 1.1 | GO:0070971 | endoplasmic reticulum exit site(GO:0070971) |
| 0.0 | 1.1 | GO:0043198 | dendritic shaft(GO:0043198) |
| 0.0 | 0.9 | GO:0005865 | striated muscle thin filament(GO:0005865) |
| 0.0 | 1.9 | GO:0016234 | inclusion body(GO:0016234) |
| 0.0 | 0.8 | GO:0042470 | melanosome(GO:0042470) pigment granule(GO:0048770) |
| 0.0 | 0.4 | GO:0043240 | Fanconi anaemia nuclear complex(GO:0043240) |
| 0.0 | 0.4 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 0.0 | 0.6 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 0.0 | 1.0 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
| 0.0 | 1.1 | GO:0031594 | neuromuscular junction(GO:0031594) |
| 0.0 | 0.7 | GO:0000407 | pre-autophagosomal structure(GO:0000407) |
| 0.0 | 0.3 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
| 0.0 | 0.1 | GO:0032156 | septin cytoskeleton(GO:0032156) |
| 0.0 | 0.2 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
| 0.0 | 0.2 | GO:0031258 | lamellipodium membrane(GO:0031258) filopodium membrane(GO:0031527) |
| 0.0 | 1.6 | GO:0000922 | spindle pole(GO:0000922) |
| 0.0 | 0.5 | GO:0035861 | site of double-strand break(GO:0035861) |
| 0.0 | 0.3 | GO:0005876 | spindle microtubule(GO:0005876) |
| 0.0 | 1.0 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
| 0.0 | 2.0 | GO:0030426 | growth cone(GO:0030426) |
| 0.0 | 0.6 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.0 | 0.2 | GO:0030126 | COPI vesicle coat(GO:0030126) |
| 0.0 | 0.1 | GO:0032777 | Piccolo NuA4 histone acetyltransferase complex(GO:0032777) |
| 0.0 | 0.7 | GO:0005884 | actin filament(GO:0005884) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 2.7 | GO:0031871 | proteinase activated receptor binding(GO:0031871) |
| 0.9 | 5.2 | GO:0070699 | type II activin receptor binding(GO:0070699) |
| 0.8 | 3.2 | GO:0001011 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) |
| 0.8 | 3.1 | GO:0086038 | calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038) |
| 0.5 | 3.2 | GO:0000155 | phosphorelay sensor kinase activity(GO:0000155) |
| 0.5 | 3.0 | GO:0008467 | [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467) |
| 0.5 | 3.3 | GO:0004971 | AMPA glutamate receptor activity(GO:0004971) |
| 0.5 | 7.0 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
| 0.4 | 5.3 | GO:0097109 | neuroligin family protein binding(GO:0097109) |
| 0.4 | 2.5 | GO:0004984 | olfactory receptor activity(GO:0004984) |
| 0.4 | 1.7 | GO:0003872 | 6-phosphofructokinase activity(GO:0003872) |
| 0.4 | 4.6 | GO:0031802 | type 5 metabotropic glutamate receptor binding(GO:0031802) |
| 0.4 | 2.4 | GO:0046975 | histone methyltransferase activity (H3-K36 specific)(GO:0046975) |
| 0.4 | 2.0 | GO:0010385 | double-stranded methylated DNA binding(GO:0010385) |
| 0.4 | 3.5 | GO:0005523 | tropomyosin binding(GO:0005523) |
| 0.4 | 1.1 | GO:0035500 | MH2 domain binding(GO:0035500) |
| 0.4 | 2.6 | GO:0015379 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
| 0.4 | 2.9 | GO:0086007 | voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007) |
| 0.4 | 3.6 | GO:0042043 | neurexin family protein binding(GO:0042043) |
| 0.3 | 4.1 | GO:0015279 | store-operated calcium channel activity(GO:0015279) |
| 0.3 | 2.7 | GO:0035033 | histone deacetylase regulator activity(GO:0035033) |
| 0.3 | 5.3 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
| 0.3 | 0.9 | GO:0098770 | FBXO family protein binding(GO:0098770) |
| 0.3 | 0.9 | GO:0030226 | apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556) |
| 0.3 | 1.2 | GO:0047275 | glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275) |
| 0.3 | 1.2 | GO:0004174 | electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649) |
| 0.3 | 1.1 | GO:0030292 | protein tyrosine kinase inhibitor activity(GO:0030292) |
| 0.3 | 1.9 | GO:0071558 | histone demethylase activity (H3-K27 specific)(GO:0071558) |
| 0.3 | 1.1 | GO:0008802 | betaine-aldehyde dehydrogenase activity(GO:0008802) |
| 0.3 | 2.4 | GO:0050291 | sphingosine N-acyltransferase activity(GO:0050291) |
| 0.3 | 1.3 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
| 0.3 | 0.8 | GO:0070890 | L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890) |
| 0.3 | 1.3 | GO:0008269 | JAK pathway signal transduction adaptor activity(GO:0008269) |
| 0.3 | 2.8 | GO:0003691 | double-stranded telomeric DNA binding(GO:0003691) |
| 0.3 | 1.0 | GO:0004176 | ATP-dependent peptidase activity(GO:0004176) |
| 0.3 | 5.3 | GO:0043422 | protein kinase B binding(GO:0043422) |
| 0.3 | 4.5 | GO:0000900 | translation repressor activity, nucleic acid binding(GO:0000900) |
| 0.3 | 2.3 | GO:0016428 | tRNA (cytosine-5-)-methyltransferase activity(GO:0016428) |
| 0.2 | 1.5 | GO:0097016 | L27 domain binding(GO:0097016) |
| 0.2 | 3.0 | GO:0001161 | intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) |
| 0.2 | 1.6 | GO:0001515 | opioid peptide activity(GO:0001515) |
| 0.2 | 0.9 | GO:0072320 | volume-sensitive chloride channel activity(GO:0072320) |
| 0.2 | 1.4 | GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468) |
| 0.2 | 1.3 | GO:0004645 | phosphorylase activity(GO:0004645) |
| 0.2 | 1.8 | GO:0097322 | 7SK snRNA binding(GO:0097322) |
| 0.2 | 1.5 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
| 0.2 | 0.9 | GO:0001639 | PLC activating G-protein coupled glutamate receptor activity(GO:0001639) G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530) |
| 0.2 | 3.7 | GO:0030553 | cGMP binding(GO:0030553) |
| 0.2 | 5.7 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
| 0.2 | 4.5 | GO:0034237 | protein kinase A regulatory subunit binding(GO:0034237) |
| 0.2 | 7.4 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
| 0.2 | 1.8 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
| 0.2 | 1.8 | GO:0004630 | phospholipase D activity(GO:0004630) |
| 0.2 | 1.1 | GO:0017151 | DEAD/H-box RNA helicase binding(GO:0017151) |
| 0.2 | 1.0 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
| 0.2 | 1.1 | GO:0043426 | MRF binding(GO:0043426) |
| 0.2 | 0.7 | GO:0047389 | glycerophosphocholine phosphodiesterase activity(GO:0047389) |
| 0.2 | 1.6 | GO:0071253 | connexin binding(GO:0071253) |
| 0.2 | 2.8 | GO:0046527 | glucosyltransferase activity(GO:0046527) |
| 0.2 | 2.3 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
| 0.2 | 6.0 | GO:0016922 | ligand-dependent nuclear receptor binding(GO:0016922) |
| 0.2 | 1.3 | GO:0046934 | phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813) |
| 0.2 | 2.8 | GO:0017166 | vinculin binding(GO:0017166) |
| 0.2 | 0.5 | GO:0004069 | L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) |
| 0.2 | 0.5 | GO:0010698 | acetyltransferase activator activity(GO:0010698) |
| 0.2 | 0.6 | GO:0004064 | arylesterase activity(GO:0004064) |
| 0.2 | 0.6 | GO:0034511 | U3 snoRNA binding(GO:0034511) |
| 0.1 | 1.2 | GO:0019869 | chloride channel inhibitor activity(GO:0019869) |
| 0.1 | 1.3 | GO:0034046 | poly(G) binding(GO:0034046) |
| 0.1 | 5.1 | GO:0070412 | R-SMAD binding(GO:0070412) |
| 0.1 | 0.7 | GO:0034186 | apolipoprotein A-I binding(GO:0034186) |
| 0.1 | 1.5 | GO:0031681 | G-protein beta-subunit binding(GO:0031681) |
| 0.1 | 0.6 | GO:0046920 | alpha-(1->3)-fucosyltransferase activity(GO:0046920) |
| 0.1 | 0.6 | GO:0098639 | collagen binding involved in cell-matrix adhesion(GO:0098639) |
| 0.1 | 0.8 | GO:0003854 | 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854) |
| 0.1 | 0.9 | GO:0086006 | voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006) |
| 0.1 | 2.8 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
| 0.1 | 6.3 | GO:0030507 | spectrin binding(GO:0030507) |
| 0.1 | 3.6 | GO:0017091 | AU-rich element binding(GO:0017091) |
| 0.1 | 0.8 | GO:0090599 | alpha-glucosidase activity(GO:0090599) |
| 0.1 | 1.0 | GO:0004691 | cyclic nucleotide-dependent protein kinase activity(GO:0004690) cAMP-dependent protein kinase activity(GO:0004691) |
| 0.1 | 0.5 | GO:0004694 | eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694) |
| 0.1 | 2.7 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
| 0.1 | 1.4 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
| 0.1 | 2.4 | GO:0046961 | proton-transporting ATPase activity, rotational mechanism(GO:0046961) |
| 0.1 | 0.9 | GO:0005225 | volume-sensitive anion channel activity(GO:0005225) |
| 0.1 | 2.3 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.1 | 0.9 | GO:1903136 | cuprous ion binding(GO:1903136) |
| 0.1 | 0.9 | GO:0061676 | importin-alpha family protein binding(GO:0061676) |
| 0.1 | 2.3 | GO:0008327 | methyl-CpG binding(GO:0008327) |
| 0.1 | 0.3 | GO:0034211 | GTP-dependent protein kinase activity(GO:0034211) |
| 0.1 | 2.5 | GO:0042169 | SH2 domain binding(GO:0042169) |
| 0.1 | 0.5 | GO:1904047 | S-adenosyl-L-methionine binding(GO:1904047) |
| 0.1 | 2.3 | GO:0017056 | structural constituent of nuclear pore(GO:0017056) |
| 0.1 | 1.4 | GO:0008569 | ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569) |
| 0.1 | 0.4 | GO:0004740 | pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740) |
| 0.1 | 0.7 | GO:0046976 | histone methyltransferase activity (H3-K27 specific)(GO:0046976) |
| 0.1 | 0.3 | GO:0004998 | transferrin receptor activity(GO:0004998) |
| 0.1 | 2.9 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
| 0.1 | 2.2 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
| 0.1 | 2.9 | GO:0051059 | NF-kappaB binding(GO:0051059) |
| 0.1 | 2.2 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 0.1 | 1.3 | GO:0004596 | peptide alpha-N-acetyltransferase activity(GO:0004596) |
| 0.1 | 0.6 | GO:0030274 | LIM domain binding(GO:0030274) |
| 0.1 | 0.6 | GO:1990825 | sequence-specific mRNA binding(GO:1990825) |
| 0.1 | 1.8 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
| 0.1 | 0.5 | GO:0061649 | ubiquitinated histone binding(GO:0061649) |
| 0.1 | 0.2 | GO:0004830 | tryptophan-tRNA ligase activity(GO:0004830) |
| 0.1 | 3.4 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
| 0.1 | 0.2 | GO:0008310 | single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310) |
| 0.1 | 1.0 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
| 0.1 | 2.4 | GO:0050750 | low-density lipoprotein particle receptor binding(GO:0050750) |
| 0.1 | 0.2 | GO:0004111 | creatine kinase activity(GO:0004111) |
| 0.1 | 1.1 | GO:0008266 | poly(U) RNA binding(GO:0008266) |
| 0.1 | 0.7 | GO:0097157 | pre-mRNA intronic binding(GO:0097157) |
| 0.1 | 5.5 | GO:0008081 | phosphoric diester hydrolase activity(GO:0008081) |
| 0.1 | 0.5 | GO:0008656 | cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656) |
| 0.1 | 0.4 | GO:0008568 | microtubule-severing ATPase activity(GO:0008568) |
| 0.1 | 0.5 | GO:0043023 | ribosomal large subunit binding(GO:0043023) |
| 0.1 | 0.4 | GO:0043995 | histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972) |
| 0.1 | 0.4 | GO:0016936 | galactoside binding(GO:0016936) |
| 0.1 | 1.8 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
| 0.1 | 0.6 | GO:0009922 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
| 0.1 | 2.8 | GO:0046875 | ephrin receptor binding(GO:0046875) |
| 0.1 | 0.3 | GO:0008294 | calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294) |
| 0.1 | 3.3 | GO:0035064 | methylated histone binding(GO:0035064) |
| 0.1 | 0.3 | GO:0033691 | sialic acid binding(GO:0033691) |
| 0.1 | 0.9 | GO:0051787 | misfolded protein binding(GO:0051787) |
| 0.1 | 1.9 | GO:0008536 | Ran GTPase binding(GO:0008536) |
| 0.1 | 0.9 | GO:0016857 | racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857) |
| 0.1 | 1.8 | GO:0001784 | phosphotyrosine binding(GO:0001784) |
| 0.1 | 0.3 | GO:0042030 | ATPase inhibitor activity(GO:0042030) |
| 0.1 | 0.9 | GO:0009982 | pseudouridine synthase activity(GO:0009982) |
| 0.1 | 1.7 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
| 0.1 | 0.3 | GO:0015186 | L-glutamine transmembrane transporter activity(GO:0015186) |
| 0.0 | 0.7 | GO:0045504 | dynein heavy chain binding(GO:0045504) |
| 0.0 | 1.5 | GO:0001103 | RNA polymerase II repressing transcription factor binding(GO:0001103) |
| 0.0 | 1.0 | GO:0042162 | telomeric DNA binding(GO:0042162) |
| 0.0 | 1.0 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
| 0.0 | 1.4 | GO:0019707 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
| 0.0 | 1.1 | GO:0031491 | nucleosome binding(GO:0031491) |
| 0.0 | 0.3 | GO:0008329 | signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187) |
| 0.0 | 2.9 | GO:0004004 | RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) |
| 0.0 | 0.1 | GO:0003987 | acetate-CoA ligase activity(GO:0003987) |
| 0.0 | 0.9 | GO:0004697 | protein kinase C activity(GO:0004697) |
| 0.0 | 0.4 | GO:0015643 | toxic substance binding(GO:0015643) |
| 0.0 | 0.2 | GO:0015265 | urea channel activity(GO:0015265) |
| 0.0 | 0.4 | GO:0004679 | AMP-activated protein kinase activity(GO:0004679) |
| 0.0 | 0.1 | GO:0019960 | C-X3-C chemokine binding(GO:0019960) |
| 0.0 | 0.7 | GO:0031489 | myosin V binding(GO:0031489) |
| 0.0 | 0.3 | GO:0009019 | tRNA (guanine-N1-)-methyltransferase activity(GO:0009019) |
| 0.0 | 1.0 | GO:0005112 | Notch binding(GO:0005112) |
| 0.0 | 2.5 | GO:0004386 | helicase activity(GO:0004386) |
| 0.0 | 1.4 | GO:0043621 | protein self-association(GO:0043621) |
| 0.0 | 0.1 | GO:0016314 | phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314) |
| 0.0 | 1.1 | GO:0005546 | phosphatidylinositol-4,5-bisphosphate binding(GO:0005546) |
| 0.0 | 0.1 | GO:0015173 | hydrogen:amino acid symporter activity(GO:0005280) aromatic amino acid transmembrane transporter activity(GO:0015173) |
| 0.0 | 0.3 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) calcium-dependent protein kinase activity(GO:0010857) |
| 0.0 | 1.2 | GO:0036002 | pre-mRNA binding(GO:0036002) |
| 0.0 | 0.1 | GO:0003963 | RNA-3'-phosphate cyclase activity(GO:0003963) |
| 0.0 | 5.2 | GO:0008017 | microtubule binding(GO:0008017) |
| 0.0 | 0.1 | GO:0060072 | large conductance calcium-activated potassium channel activity(GO:0060072) |
| 0.0 | 0.5 | GO:0043395 | heparan sulfate proteoglycan binding(GO:0043395) |
| 0.0 | 0.3 | GO:0022889 | L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889) |
| 0.0 | 0.2 | GO:0032454 | histone demethylase activity (H3-K9 specific)(GO:0032454) |
| 0.0 | 0.5 | GO:0000993 | RNA polymerase II core binding(GO:0000993) |
| 0.0 | 0.7 | GO:0004693 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) |
| 0.0 | 0.1 | GO:0052833 | inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834) |
| 0.0 | 0.1 | GO:0043734 | DNA-N1-methyladenine dioxygenase activity(GO:0043734) |
| 0.0 | 0.2 | GO:0033130 | acetylcholine receptor binding(GO:0033130) |
| 0.0 | 3.3 | GO:0008022 | protein C-terminus binding(GO:0008022) |
| 0.0 | 0.1 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
| 0.0 | 0.3 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 0.0 | 0.5 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
| 0.0 | 0.2 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) |
| 0.0 | 0.6 | GO:0005179 | hormone activity(GO:0005179) |
| 0.0 | 0.1 | GO:0004105 | choline-phosphate cytidylyltransferase activity(GO:0004105) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 1.8 | PID_UPA_UPAR_PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
| 0.2 | 6.8 | PID_BETA_CATENIN_DEG_PATHWAY | Degradation of beta catenin |
| 0.2 | 0.4 | PID_AMB2_NEUTROPHILS_PATHWAY | amb2 Integrin signaling |
| 0.2 | 1.3 | PID_IL2_1PATHWAY | IL2-mediated signaling events |
| 0.1 | 7.7 | PID_HNF3A_PATHWAY | FOXA1 transcription factor network |
| 0.1 | 3.5 | PID_ARF6_DOWNSTREAM_PATHWAY | Arf6 downstream pathway |
| 0.1 | 1.5 | PID_THROMBIN_PAR4_PATHWAY | PAR4-mediated thrombin signaling events |
| 0.1 | 4.7 | PID_ATM_PATHWAY | ATM pathway |
| 0.1 | 4.3 | PID_LIS1_PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 0.1 | 1.1 | PID_ALK2_PATHWAY | ALK2 signaling events |
| 0.1 | 1.6 | PID_RANBP2_PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
| 0.1 | 2.1 | PID_EPHA2_FWD_PATHWAY | EPHA2 forward signaling |
| 0.1 | 1.7 | PID_CDC42_PATHWAY | CDC42 signaling events |
| 0.1 | 0.8 | PID_TCR_JNK_PATHWAY | JNK signaling in the CD4+ TCR pathway |
| 0.1 | 2.4 | PID_WNT_NONCANONICAL_PATHWAY | Noncanonical Wnt signaling pathway |
| 0.1 | 5.1 | PID_RHOA_REG_PATHWAY | Regulation of RhoA activity |
| 0.1 | 1.9 | PID_PS1_PATHWAY | Presenilin action in Notch and Wnt signaling |
| 0.1 | 1.1 | PID_CDC42_REG_PATHWAY | Regulation of CDC42 activity |
| 0.1 | 2.4 | PID_TNF_PATHWAY | TNF receptor signaling pathway |
| 0.1 | 0.8 | PID_HEDGEHOG_2PATHWAY | Signaling events mediated by the Hedgehog family |
| 0.1 | 0.8 | PID_ANTHRAX_PATHWAY | Cellular roles of Anthrax toxin |
| 0.1 | 2.7 | PID_ERA_GENOMIC_PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.0 | 1.6 | PID_RET_PATHWAY | Signaling events regulated by Ret tyrosine kinase |
| 0.0 | 2.4 | SIG_PIP3_SIGNALING_IN_B_LYMPHOCYTES | Genes related to PIP3 signaling in B lymphocytes |
| 0.0 | 3.8 | PID_E2F_PATHWAY | E2F transcription factor network |
| 0.0 | 0.3 | ST_GA13_PATHWAY | G alpha 13 Pathway |
| 0.0 | 1.8 | PID_HEDGEHOG_GLI_PATHWAY | Hedgehog signaling events mediated by Gli proteins |
| 0.0 | 1.4 | PID_ECADHERIN_NASCENT_AJ_PATHWAY | E-cadherin signaling in the nascent adherens junction |
| 0.0 | 0.9 | PID_ARF_3PATHWAY | Arf1 pathway |
| 0.0 | 0.6 | PID_CERAMIDE_PATHWAY | Ceramide signaling pathway |
| 0.0 | 0.7 | PID_RAC1_PATHWAY | RAC1 signaling pathway |
| 0.0 | 0.7 | PID_TOLL_ENDOGENOUS_PATHWAY | Endogenous TLR signaling |
| 0.0 | 0.2 | PID_AR_NONGENOMIC_PATHWAY | Nongenotropic Androgen signaling |
| 0.0 | 0.9 | PID_ATF2_PATHWAY | ATF-2 transcription factor network |
| 0.0 | 0.7 | PID_PI3KCI_AKT_PATHWAY | Class I PI3K signaling events mediated by Akt |
| 0.0 | 1.3 | PID_ERBB1_INTERNALIZATION_PATHWAY | Internalization of ErbB1 |
| 0.0 | 1.0 | PID_P53_REGULATION_PATHWAY | p53 pathway |
| 0.0 | 0.8 | PID_ECADHERIN_STABILIZATION_PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
| 0.0 | 0.3 | PID_LPA4_PATHWAY | LPA4-mediated signaling events |
| 0.0 | 1.1 | PID_PLK1_PATHWAY | PLK1 signaling events |
| 0.0 | 0.4 | PID_ALK1_PATHWAY | ALK1 signaling events |
| 0.0 | 1.5 | PID_P53_DOWNSTREAM_PATHWAY | Direct p53 effectors |
| 0.0 | 0.8 | PID_AR_TF_PATHWAY | Regulation of Androgen receptor activity |
| 0.0 | 0.7 | PID_IL6_7_PATHWAY | IL6-mediated signaling events |
| 0.0 | 0.1 | PID_NECTIN_PATHWAY | Nectin adhesion pathway |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.1 | 4.4 | REACTOME_GLYCOPROTEIN_HORMONES | Genes involved in Glycoprotein hormones |
| 0.4 | 2.4 | REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS | Genes involved in Creation of C4 and C2 activators |
| 0.4 | 6.5 | REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY | Genes involved in Notch-HLH transcription pathway |
| 0.4 | 9.7 | REACTOME_RNA_POL_III_TRANSCRIPTION_TERMINATION | Genes involved in RNA Polymerase III Transcription Termination |
| 0.3 | 1.6 | REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS | Genes involved in Apoptotic cleavage of cell adhesion proteins |
| 0.3 | 5.7 | REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE | Genes involved in Beta-catenin phosphorylation cascade |
| 0.3 | 7.9 | REACTOME_UNBLOCKING_OF_NMDA_RECEPTOR_GLUTAMATE_BINDING_AND_ACTIVATION | Genes involved in Unblocking of NMDA receptor, glutamate binding and activation |
| 0.2 | 4.3 | REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS | Genes involved in Homologous recombination repair of replication-independent double-strand breaks |
| 0.2 | 10.1 | REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS | Genes involved in Voltage gated Potassium channels |
| 0.2 | 3.1 | REACTOME_PLATELET_CALCIUM_HOMEOSTASIS | Genes involved in Platelet calcium homeostasis |
| 0.2 | 4.9 | REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA | Genes involved in Circadian Repression of Expression by REV-ERBA |
| 0.2 | 1.0 | REACTOME_DSCAM_INTERACTIONS | Genes involved in DSCAM interactions |
| 0.2 | 1.9 | REACTOME_IL_6_SIGNALING | Genes involved in Interleukin-6 signaling |
| 0.1 | 3.7 | REACTOME_CGMP_EFFECTS | Genes involved in cGMP effects |
| 0.1 | 1.3 | REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |
| 0.1 | 2.7 | REACTOME_TRANSFERRIN_ENDOCYTOSIS_AND_RECYCLING | Genes involved in Transferrin endocytosis and recycling |
| 0.1 | 3.8 | REACTOME_TRANSPORT_OF_RIBONUCLEOPROTEINS_INTO_THE_HOST_NUCLEUS | Genes involved in Transport of Ribonucleoproteins into the Host Nucleus |
| 0.1 | 2.5 | REACTOME_ELONGATION_ARREST_AND_RECOVERY | Genes involved in Elongation arrest and recovery |
| 0.1 | 0.9 | REACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN1_SIGNALING | Genes involved in Role of second messengers in netrin-1 signaling |
| 0.1 | 0.8 | REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol |
| 0.1 | 2.8 | REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN | Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein |
| 0.1 | 1.8 | REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS | Genes involved in ABCA transporters in lipid homeostasis |
| 0.1 | 3.4 | REACTOME_HS_GAG_BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
| 0.1 | 2.2 | REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
| 0.1 | 1.8 | REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 0.1 | 2.1 | REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI | Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) |
| 0.1 | 1.6 | REACTOME_SIGNAL_ATTENUATION | Genes involved in Signal attenuation |
| 0.1 | 1.2 | REACTOME_GABA_A_RECEPTOR_ACTIVATION | Genes involved in GABA A receptor activation |
| 0.1 | 2.4 | REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.1 | 2.5 | REACTOME_MYOGENESIS | Genes involved in Myogenesis |
| 0.1 | 1.0 | REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION | Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion |
| 0.1 | 2.3 | REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES | Genes involved in Ion transport by P-type ATPases |
| 0.1 | 0.9 | REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
| 0.1 | 1.3 | REACTOME_EGFR_DOWNREGULATION | Genes involved in EGFR downregulation |
| 0.1 | 5.5 | REACTOME_L1CAM_INTERACTIONS | Genes involved in L1CAM interactions |
| 0.1 | 2.4 | REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.1 | 0.7 | REACTOME_IRAK1_RECRUITS_IKK_COMPLEX | Genes involved in IRAK1 recruits IKK complex |
| 0.0 | 0.0 | REACTOME_DESTABILIZATION_OF_MRNA_BY_KSRP | Genes involved in Destabilization of mRNA by KSRP |
| 0.0 | 0.6 | REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION | Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation |
| 0.0 | 1.5 | REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
| 0.0 | 0.6 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE | Genes involved in Synthesis of PIPs at the early endosome membrane |
| 0.0 | 1.7 | REACTOME_PLC_BETA_MEDIATED_EVENTS | Genes involved in PLC beta mediated events |
| 0.0 | 1.8 | REACTOME_MRNA_3_END_PROCESSING | Genes involved in mRNA 3'-end processing |
| 0.0 | 0.6 | REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM | Genes involved in alpha-linolenic acid (ALA) metabolism |
| 0.0 | 1.0 | REACTOME_SIGNALING_BY_BMP | Genes involved in Signaling by BMP |
| 0.0 | 0.6 | REACTOME_DESTABILIZATION_OF_MRNA_BY_TRISTETRAPROLIN_TTP | Genes involved in Destabilization of mRNA by Tristetraprolin (TTP) |
| 0.0 | 2.6 | REACTOME_MRNA_SPLICING | Genes involved in mRNA Splicing |
| 0.0 | 0.5 | REACTOME_REGULATION_OF_SIGNALING_BY_CBL | Genes involved in Regulation of signaling by CBL |
| 0.0 | 0.9 | REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS | Genes involved in Effects of PIP2 hydrolysis |
| 0.0 | 0.1 | REACTOME_ETHANOL_OXIDATION | Genes involved in Ethanol oxidation |
| 0.0 | 0.5 | REACTOME_NEPHRIN_INTERACTIONS | Genes involved in Nephrin interactions |
| 0.0 | 0.4 | REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
| 0.0 | 0.5 | REACTOME_PERK_REGULATED_GENE_EXPRESSION | Genes involved in PERK regulated gene expression |
| 0.0 | 0.4 | REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS | Genes involved in Trafficking of AMPA receptors |
| 0.0 | 0.3 | REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
| 0.0 | 0.5 | REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION | Genes involved in Amino acid synthesis and interconversion (transamination) |
| 0.0 | 1.2 | REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
| 0.0 | 0.8 | REACTOME_TRANSPORT_TO_THE_GOLGI_AND_SUBSEQUENT_MODIFICATION | Genes involved in Transport to the Golgi and subsequent modification |
| 0.0 | 1.9 | REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
| 0.0 | 0.2 | REACTOME_COPI_MEDIATED_TRANSPORT | Genes involved in COPI Mediated Transport |
| 0.0 | 1.0 | REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |
| 0.0 | 0.2 | REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS | Genes involved in Amine compound SLC transporters |
| 0.0 | 0.4 | REACTOME_DARPP_32_EVENTS | Genes involved in DARPP-32 events |
| 0.0 | 0.3 | REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
| 0.0 | 0.6 | REACTOME_G1_PHASE | Genes involved in G1 Phase |
| 0.0 | 0.6 | REACTOME_NCAM1_INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.0 | 0.2 | REACTOME_NOD1_2_SIGNALING_PATHWAY | Genes involved in NOD1/2 Signaling Pathway |
| 0.0 | 0.5 | REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES | Genes involved in Antiviral mechanism by IFN-stimulated genes |
| 0.0 | 0.2 | REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING | Genes involved in Growth hormone receptor signaling |
