Motif ID: Nfia

Z-value: 2.010


Transcription factors associated with Nfia:

Gene SymbolEntrez IDGene Name
Nfia ENSMUSG00000028565.12 Nfia

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nfiamm10_v2_chr4_+_97772734_97772848-0.056.4e-01Click!


Activity profile for motif Nfia.

activity profile for motif Nfia


Sorted Z-values histogram for motif Nfia

Sorted Z-values for motif Nfia



Network of associatons between targets according to the STRING database.



First level regulatory network of Nfia

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr18_+_20665250 34.584 ENSMUST00000075312.3
Ttr
transthyretin
chr19_+_5740885 31.503 ENSMUST00000081496.5
Ltbp3
latent transforming growth factor beta binding protein 3
chr6_+_141524379 28.084 ENSMUST00000032362.9
Slco1c1
solute carrier organic anion transporter family, member 1c1
chr10_+_127725392 22.529 ENSMUST00000026466.3
Tac2
tachykinin 2
chr7_+_130936172 21.451 ENSMUST00000006367.7
Htra1
HtrA serine peptidase 1
chr13_-_97747373 18.900 ENSMUST00000123535.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr11_-_102897123 18.508 ENSMUST00000067444.3
Gfap
glial fibrillary acidic protein
chr7_-_97417730 17.731 ENSMUST00000043077.7
Thrsp
thyroid hormone responsive
chr1_+_42229726 17.150 ENSMUST00000066196.1
Gm9915
predicted gene 9915
chr13_-_97747399 16.114 ENSMUST00000144993.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr12_+_85473883 15.655 ENSMUST00000021674.6
Fos
FBJ osteosarcoma oncogene
chr13_+_94173992 15.023 ENSMUST00000121618.1
Lhfpl2
lipoma HMGIC fusion partner-like 2
chr4_+_48045144 14.639 ENSMUST00000030025.3
Nr4a3
nuclear receptor subfamily 4, group A, member 3
chr11_-_77894096 14.338 ENSMUST00000017597.4
Pipox
pipecolic acid oxidase
chr11_-_102897146 14.153 ENSMUST00000077902.4
Gfap
glial fibrillary acidic protein
chr10_+_58813359 14.083 ENSMUST00000135526.2
ENSMUST00000153031.1
Sh3rf3

SH3 domain containing ring finger 3

chr3_-_116129615 13.316 ENSMUST00000029574.8
Vcam1
vascular cell adhesion molecule 1
chr3_+_89520152 12.394 ENSMUST00000000811.7
Kcnn3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr2_-_25469742 12.376 ENSMUST00000114259.2
ENSMUST00000015234.6
Ptgds

prostaglandin D2 synthase (brain)

chr2_-_170194033 12.351 ENSMUST00000180625.1
Gm17619
predicted gene, 17619
chr2_-_25470031 11.897 ENSMUST00000114251.1
Ptgds
prostaglandin D2 synthase (brain)
chr11_+_78324200 11.630 ENSMUST00000102478.3
Aldoc
aldolase C, fructose-bisphosphate
chr14_-_118052235 11.553 ENSMUST00000022725.2
Dct
dopachrome tautomerase
chr17_-_34972124 10.631 ENSMUST00000087328.2
ENSMUST00000179128.1
Hspa1a

heat shock protein 1A

chr2_-_155945282 10.063 ENSMUST00000040162.2
Gdf5
growth differentiation factor 5
chr11_+_61485431 9.963 ENSMUST00000064783.3
ENSMUST00000040522.6
Mfap4

microfibrillar-associated protein 4

chr8_+_84723003 9.467 ENSMUST00000098571.4
G430095P16Rik
RIKEN cDNA G430095P16 gene
chr2_+_32646586 9.291 ENSMUST00000009705.7
ENSMUST00000167841.1
Eng

endoglin

chr1_+_51289106 9.263 ENSMUST00000051572.6
Sdpr
serum deprivation response
chr2_-_77703252 9.210 ENSMUST00000171063.1
Zfp385b
zinc finger protein 385B
chr6_-_125313844 9.174 ENSMUST00000032489.7
Ltbr
lymphotoxin B receptor
chr5_+_66968559 9.123 ENSMUST00000127184.1
Limch1
LIM and calponin homology domains 1
chr4_-_64046925 9.069 ENSMUST00000107377.3
Tnc
tenascin C
chr12_+_84009481 9.010 ENSMUST00000168120.1
Acot1
acyl-CoA thioesterase 1
chr6_-_115251839 8.794 ENSMUST00000032462.6
Timp4
tissue inhibitor of metalloproteinase 4
chr5_-_124352233 8.759 ENSMUST00000111472.1
Cdk2ap1
CDK2 (cyclin-dependent kinase 2)-associated protein 1
chr4_-_148287927 8.752 ENSMUST00000047720.8
Ptchd2
patched domain containing 2
chr5_+_66968416 8.664 ENSMUST00000038188.7
Limch1
LIM and calponin homology domains 1
chr17_+_34564268 8.656 ENSMUST00000015612.7
Notch4
notch 4
chr11_+_3330401 8.578 ENSMUST00000045153.4
Pik3ip1
phosphoinositide-3-kinase interacting protein 1
chr4_+_88094599 8.376 ENSMUST00000097992.3
Focad
focadhesin
chr7_-_120202104 8.322 ENSMUST00000033198.5
Crym
crystallin, mu
chr6_-_54593139 8.261 ENSMUST00000046520.6
Fkbp14
FK506 binding protein 14
chr11_+_3330781 8.025 ENSMUST00000136536.1
ENSMUST00000093399.4
Pik3ip1

phosphoinositide-3-kinase interacting protein 1

chr3_+_94933041 7.985 ENSMUST00000090839.5
Selenbp1
selenium binding protein 1
chr17_-_25570678 7.919 ENSMUST00000025003.3
ENSMUST00000173447.1
Sox8

SRY-box containing gene 8

chr2_+_85136355 7.856 ENSMUST00000057019.7
Aplnr
apelin receptor
chr4_+_11704439 7.791 ENSMUST00000108304.2
Gem
GTP binding protein (gene overexpressed in skeletal muscle)
chr10_+_57784859 7.539 ENSMUST00000020024.5
Fabp7
fatty acid binding protein 7, brain
chr3_+_90537306 7.526 ENSMUST00000107335.1
S100a16
S100 calcium binding protein A16
chr1_-_163725123 7.495 ENSMUST00000159679.1
Mettl11b
methyltransferase like 11B
chr7_-_46179929 7.478 ENSMUST00000033123.6
Abcc8
ATP-binding cassette, sub-family C (CFTR/MRP), member 8
chr7_+_45017953 7.447 ENSMUST00000044111.7
Rras
Harvey rat sarcoma oncogene, subgroup R
chr11_-_114795888 7.362 ENSMUST00000000206.3
Btbd17
BTB (POZ) domain containing 17
chr3_-_90514250 7.279 ENSMUST00000107340.1
ENSMUST00000060738.8
S100a1

S100 calcium binding protein A1

chr3_+_90537242 7.170 ENSMUST00000098911.3
S100a16
S100 calcium binding protein A16
chr14_+_19751257 7.106 ENSMUST00000022340.3
Nid2
nidogen 2
chr2_+_33216051 7.076 ENSMUST00000004208.5
Angptl2
angiopoietin-like 2
chr13_+_38345716 7.018 ENSMUST00000171970.1
Bmp6
bone morphogenetic protein 6
chr1_-_45503282 6.980 ENSMUST00000086430.4
Col5a2
collagen, type V, alpha 2
chr6_+_17306335 6.820 ENSMUST00000007799.6
ENSMUST00000115456.1
ENSMUST00000115455.2
ENSMUST00000130505.1
Cav1



caveolin 1, caveolae protein



chr17_+_34969912 6.781 ENSMUST00000173680.1
Gm20481
predicted gene 20481
chr5_-_104114088 6.733 ENSMUST00000031249.3
Sparcl1
SPARC-like 1
chr2_+_25180737 6.703 ENSMUST00000104999.2
Nrarp
Notch-regulated ankyrin repeat protein
chr7_+_78578830 6.631 ENSMUST00000064591.4
Gm9885
predicted gene 9885
chr3_+_66219909 6.594 ENSMUST00000029421.5
Ptx3
pentraxin related gene
chr5_+_64812336 6.591 ENSMUST00000166409.1
Klf3
Kruppel-like factor 3 (basic)
chr11_+_3332426 6.525 ENSMUST00000136474.1
Pik3ip1
phosphoinositide-3-kinase interacting protein 1
chrX_+_166344692 6.516 ENSMUST00000112223.1
ENSMUST00000112224.1
ENSMUST00000112229.2
ENSMUST00000112228.1
ENSMUST00000112227.2
ENSMUST00000112226.2
Gpm6b





glycoprotein m6b





chr6_+_125552948 6.488 ENSMUST00000112254.1
ENSMUST00000112253.1
ENSMUST00000001995.7
Vwf


Von Willebrand factor homolog


chr1_-_172219715 6.452 ENSMUST00000170700.1
ENSMUST00000003554.4
Casq1

calsequestrin 1

chrX_-_142306170 6.452 ENSMUST00000134825.2
Kcne1l
potassium voltage-gated channel, Isk-related family, member 1-like, pseudogene
chr3_-_108226598 6.431 ENSMUST00000029486.7
ENSMUST00000156371.1
ENSMUST00000141387.1
Sypl2


synaptophysin-like 2


chr4_-_133967953 6.386 ENSMUST00000102553.4
Hmgn2
high mobility group nucleosomal binding domain 2
chr7_-_78577771 6.341 ENSMUST00000039438.7
Ntrk3
neurotrophic tyrosine kinase, receptor, type 3
chr7_+_99466004 6.301 ENSMUST00000037359.2
Klhl35
kelch-like 35
chr5_+_118169712 6.299 ENSMUST00000054836.6
Hrk
harakiri, BCL2 interacting protein (contains only BH3 domain)
chr6_+_112273758 6.295 ENSMUST00000032376.5
Lmcd1
LIM and cysteine-rich domains 1
chr6_+_115134899 6.276 ENSMUST00000009538.5
ENSMUST00000169345.1
Syn2

synapsin II

chr13_-_23622502 6.276 ENSMUST00000062045.2
Hist1h1e
histone cluster 1, H1e
chr11_+_78499087 6.227 ENSMUST00000017488.4
Vtn
vitronectin
chr11_-_84068357 6.184 ENSMUST00000100705.4
Dusp14
dual specificity phosphatase 14
chr17_-_34959232 6.135 ENSMUST00000165202.1
ENSMUST00000172753.1
Hspa1b

heat shock protein 1B

chr12_+_37880700 6.096 ENSMUST00000040500.7
Dgkb
diacylglycerol kinase, beta
chr2_+_122147680 6.072 ENSMUST00000102476.4
B2m
beta-2 microglobulin
chr14_+_101840602 6.051 ENSMUST00000159314.1
Lmo7
LIM domain only 7
chr16_-_85803106 6.046 ENSMUST00000023610.8
Adamts1
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1
chr7_+_114745685 6.034 ENSMUST00000136645.1
ENSMUST00000169913.1
Insc

inscuteable homolog (Drosophila)

chr15_+_79892397 5.980 ENSMUST00000175714.1
ENSMUST00000109620.3
ENSMUST00000165537.1
Apobec3


apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3


chr14_+_32028989 5.869 ENSMUST00000022460.4
Galnt15
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 15
chr17_+_86753900 5.812 ENSMUST00000024954.9
Epas1
endothelial PAS domain protein 1
chr9_-_51278540 5.755 ENSMUST00000114427.3
Gm684
predicted gene 684
chr4_+_137468767 5.741 ENSMUST00000030547.8
ENSMUST00000171332.1
Hspg2

perlecan (heparan sulfate proteoglycan 2)

chr1_-_56969864 5.692 ENSMUST00000177424.1
Satb2
special AT-rich sequence binding protein 2
chr7_-_25788635 5.661 ENSMUST00000002677.4
ENSMUST00000085948.4
Axl

AXL receptor tyrosine kinase

chr19_-_8929323 5.648 ENSMUST00000096242.3
Rom1
rod outer segment membrane protein 1
chr11_-_100411874 5.640 ENSMUST00000141840.1
Leprel4
leprecan-like 4
chr16_+_43510267 5.633 ENSMUST00000114695.2
Zbtb20
zinc finger and BTB domain containing 20
chrX_+_10485121 5.631 ENSMUST00000076354.6
ENSMUST00000115526.1
Tspan7

tetraspanin 7

chr1_+_185454803 5.595 ENSMUST00000061093.6
Slc30a10
solute carrier family 30, member 10
chr1_-_190170178 5.541 ENSMUST00000177288.1
Prox1
prospero-related homeobox 1
chr8_-_105484350 5.540 ENSMUST00000044286.5
Zdhhc1
zinc finger, DHHC domain containing 1
chr15_-_3583191 5.528 ENSMUST00000069451.4
Ghr
growth hormone receptor
chr11_-_84068554 5.524 ENSMUST00000164891.1
Dusp14
dual specificity phosphatase 14
chr5_+_149411749 5.502 ENSMUST00000093110.5
Medag
mesenteric estrogen dependent adipogenesis
chr16_-_36784784 5.444 ENSMUST00000165531.1
Slc15a2
solute carrier family 15 (H+/peptide transporter), member 2
chr2_+_59612034 5.410 ENSMUST00000112568.1
ENSMUST00000037526.4
Tanc1

tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1

chr8_+_57455898 5.407 ENSMUST00000034023.3
Scrg1
scrapie responsive gene 1
chr2_+_133552159 5.369 ENSMUST00000028836.6
Bmp2
bone morphogenetic protein 2
chr15_+_79892436 5.278 ENSMUST00000175752.1
ENSMUST00000176325.1
Apobec3

apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3

chr17_-_72603709 5.275 ENSMUST00000086639.4
Alk
anaplastic lymphoma kinase
chr4_-_108032069 5.263 ENSMUST00000106709.2
Podn
podocan
chr7_-_80403315 5.236 ENSMUST00000147150.1
Furin
furin (paired basic amino acid cleaving enzyme)
chr4_-_118489755 5.192 ENSMUST00000184261.1
Tie1
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr11_+_109485606 5.188 ENSMUST00000106697.1
Arsg
arylsulfatase G
chr4_-_133967893 5.175 ENSMUST00000100472.3
ENSMUST00000136327.1
Hmgn2

high mobility group nucleosomal binding domain 2

chr1_-_190169399 5.151 ENSMUST00000010319.7
Prox1
prospero-related homeobox 1
chr12_-_70347536 5.149 ENSMUST00000110520.2
ENSMUST00000110522.2
ENSMUST00000167755.1
Trim9


tripartite motif-containing 9


chr6_+_138140298 5.075 ENSMUST00000008684.4
Mgst1
microsomal glutathione S-transferase 1
chr9_-_79718518 5.061 ENSMUST00000071750.6
Col12a1
collagen, type XII, alpha 1
chr3_+_86084434 5.051 ENSMUST00000107664.2
Sh3d19
SH3 domain protein D19
chr16_+_91269759 5.026 ENSMUST00000056882.5
Olig1
oligodendrocyte transcription factor 1
chr14_+_13454010 5.015 ENSMUST00000112656.2
Synpr
synaptoporin
chr4_-_147936713 4.984 ENSMUST00000105712.1
ENSMUST00000019199.7
Plod1

procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1

chr2_-_127482499 4.973 ENSMUST00000088538.5
Kcnip3
Kv channel interacting protein 3, calsenilin
chr6_+_138140521 4.960 ENSMUST00000120939.1
ENSMUST00000120302.1
Mgst1

microsomal glutathione S-transferase 1

chr6_+_117168535 4.924 ENSMUST00000112866.1
ENSMUST00000112871.1
ENSMUST00000073043.4
Cxcl12


chemokine (C-X-C motif) ligand 12


chr6_+_134920401 4.869 ENSMUST00000067327.4
ENSMUST00000003115.6
Cdkn1b

cyclin-dependent kinase inhibitor 1B

chr1_-_77515048 4.855 ENSMUST00000027451.6
Epha4
Eph receptor A4
chr2_+_105668935 4.800 ENSMUST00000142772.1
Pax6
paired box gene 6
chr2_-_114052804 4.785 ENSMUST00000090269.6
Actc1
actin, alpha, cardiac muscle 1
chr15_+_25773985 4.783 ENSMUST00000125667.1
Myo10
myosin X
chr15_-_3583146 4.782 ENSMUST00000110698.2
Ghr
growth hormone receptor
chr18_+_8694077 4.769 ENSMUST00000171469.1
Gm5819
predicted gene 5819
chr14_+_55491062 4.702 ENSMUST00000076236.5
Lrrc16b
leucine rich repeat containing 16B
chr1_+_169928648 4.662 ENSMUST00000094348.3
1700084C01Rik
RIKEN cDNA 1700084C01 gene
chr7_+_27605797 4.650 ENSMUST00000143499.1
ENSMUST00000108343.1
Akt2

thymoma viral proto-oncogene 2

chr6_+_108213086 4.646 ENSMUST00000032192.6
Itpr1
inositol 1,4,5-trisphosphate receptor 1
chr9_-_121277160 4.631 ENSMUST00000051479.6
ENSMUST00000171923.1
Ulk4

unc-51-like kinase 4

chr17_-_49564262 4.616 ENSMUST00000057610.6
Daam2
dishevelled associated activator of morphogenesis 2
chrX_+_99975570 4.607 ENSMUST00000113779.1
ENSMUST00000113776.1
ENSMUST00000113775.1
ENSMUST00000113780.1
ENSMUST00000113778.1
ENSMUST00000113781.1
ENSMUST00000113783.1
ENSMUST00000071453.2
ENSMUST00000113777.1
Eda








ectodysplasin-A








chr5_+_111733924 4.602 ENSMUST00000180627.1
Gm26897
predicted gene, 26897
chr1_-_56969827 4.532 ENSMUST00000176759.1
Satb2
special AT-rich sequence binding protein 2
chr2_-_116065798 4.481 ENSMUST00000110907.1
ENSMUST00000110908.2
Meis2

Meis homeobox 2

chr2_+_105668888 4.481 ENSMUST00000111086.4
ENSMUST00000111087.3
Pax6

paired box gene 6

chr7_+_27605847 4.481 ENSMUST00000051356.5
Akt2
thymoma viral proto-oncogene 2
chr7_+_120843551 4.468 ENSMUST00000106489.1
ENSMUST00000143279.1
Eef2k

eukaryotic elongation factor-2 kinase

chr5_+_66745835 4.457 ENSMUST00000101164.4
ENSMUST00000118242.1
ENSMUST00000119854.1
ENSMUST00000117601.1
Limch1



LIM and calponin homology domains 1



chr9_-_54661870 4.419 ENSMUST00000034822.5
Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr9_-_103222063 4.408 ENSMUST00000170904.1
Trf
transferrin
chr7_+_113207465 4.391 ENSMUST00000047321.7
Arntl
aryl hydrocarbon receptor nuclear translocator-like
chr5_+_66968961 4.359 ENSMUST00000132991.1
Limch1
LIM and calponin homology domains 1
chr17_-_34000257 4.355 ENSMUST00000087189.6
ENSMUST00000173075.1
ENSMUST00000172760.1
ENSMUST00000172912.1
ENSMUST00000025181.10
H2-K1




histocompatibility 2, K1, K region




chr12_-_84876479 4.317 ENSMUST00000163189.1
ENSMUST00000110254.2
ENSMUST00000002073.6
Ltbp2


latent transforming growth factor beta binding protein 2


chr14_-_118237016 4.316 ENSMUST00000170662.1
Sox21
SRY-box containing gene 21
chr12_+_75308308 4.296 ENSMUST00000118602.1
ENSMUST00000118966.1
ENSMUST00000055390.5
Rhoj


ras homolog gene family, member J


chr15_-_78405824 4.261 ENSMUST00000058659.7
Tst
thiosulfate sulfurtransferase, mitochondrial
chr5_+_139423151 4.228 ENSMUST00000066211.4
Gper1
G protein-coupled estrogen receptor 1
chr1_+_136131382 4.207 ENSMUST00000075164.4
Kif21b
kinesin family member 21B
chr12_+_36314160 4.203 ENSMUST00000041407.5
Sostdc1
sclerostin domain containing 1
chr4_-_4138432 4.202 ENSMUST00000070375.7
Penk
preproenkephalin
chr14_+_101840501 4.198 ENSMUST00000159026.1
Lmo7
LIM domain only 7
chr1_+_169929929 4.196 ENSMUST00000175731.1
1700084C01Rik
RIKEN cDNA 1700084C01 gene
chr4_-_108031938 4.041 ENSMUST00000106708.1
Podn
podocan
chr7_+_141476374 4.028 ENSMUST00000117634.1
Tspan4
tetraspanin 4
chr3_+_137341103 3.999 ENSMUST00000119475.1
Emcn
endomucin
chr14_+_13453937 3.980 ENSMUST00000153954.1
Synpr
synaptoporin
chr6_+_90465287 3.955 ENSMUST00000113530.1
Klf15
Kruppel-like factor 15
chr1_+_180330470 3.954 ENSMUST00000070181.6
Itpkb
inositol 1,4,5-trisphosphate 3-kinase B
chr19_-_7105729 3.946 ENSMUST00000113383.2
Flrt1
fibronectin leucine rich transmembrane protein 1
chr7_+_25659153 3.918 ENSMUST00000079634.6
Exosc5
exosome component 5
chr5_+_123015010 3.902 ENSMUST00000121652.1
ENSMUST00000051016.4
Orai1

ORAI calcium release-activated calcium modulator 1

chr10_-_105574435 3.874 ENSMUST00000061506.8
Tmtc2
transmembrane and tetratricopeptide repeat containing 2
chr16_+_23290464 3.867 ENSMUST00000115335.1
St6gal1
beta galactoside alpha 2,6 sialyltransferase 1
chr10_+_17723220 3.855 ENSMUST00000038107.7
Cited2
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
chr18_+_52767994 3.807 ENSMUST00000025413.7
ENSMUST00000163742.2
ENSMUST00000178011.1
Sncaip


synuclein, alpha interacting protein (synphilin)


chr5_+_24364804 3.760 ENSMUST00000030834.4
ENSMUST00000115090.1
Nos3

nitric oxide synthase 3, endothelial cell

chr4_-_133967235 3.757 ENSMUST00000123234.1
Hmgn2
high mobility group nucleosomal binding domain 2
chr3_+_127633134 3.741 ENSMUST00000029587.7
Neurog2
neurogenin 2
chr11_-_116110211 3.737 ENSMUST00000106441.1
ENSMUST00000021120.5
Trim47

tripartite motif-containing 47

chr2_+_152143552 3.728 ENSMUST00000089112.5
Tcf15
transcription factor 15
chr8_+_71406003 3.728 ENSMUST00000119976.1
ENSMUST00000120725.1
Ankle1

ankyrin repeat and LEM domain containing 1

chr7_-_78578308 3.704 ENSMUST00000039431.7
Ntrk3
neurotrophic tyrosine kinase, receptor, type 3
chr4_-_42661893 3.697 ENSMUST00000108006.3
Il11ra2
interleukin 11 receptor, alpha chain 2
chr12_-_75735729 3.695 ENSMUST00000021450.4
Sgpp1
sphingosine-1-phosphate phosphatase 1
chr18_-_39490649 3.671 ENSMUST00000115567.1
Nr3c1
nuclear receptor subfamily 3, group C, member 1
chr5_-_44226601 3.649 ENSMUST00000055128.7
Tapt1
transmembrane anterior posterior transformation 1
chr7_+_35119285 3.644 ENSMUST00000042985.9
Cebpa
CCAAT/enhancer binding protein (C/EBP), alpha
chr7_-_19715395 3.623 ENSMUST00000032555.9
ENSMUST00000093552.5
Tomm40

translocase of outer mitochondrial membrane 40 homolog (yeast)

chr9_-_62070606 3.618 ENSMUST00000034785.7
Glce
glucuronyl C5-epimerase
chr7_+_141061274 3.574 ENSMUST00000048002.5
B4galnt4
beta-1,4-N-acetyl-galactosaminyl transferase 4
chr7_+_120842824 3.568 ENSMUST00000047875.8
Eef2k
eukaryotic elongation factor-2 kinase
chr4_-_155992604 3.559 ENSMUST00000052185.3
B3galt6
UDP-Gal:betaGal beta 1,3-galactosyltransferase, polypeptide 6
chr10_+_116301374 3.538 ENSMUST00000092167.5
Ptprb
protein tyrosine phosphatase, receptor type, B
chr17_-_35697971 3.534 ENSMUST00000146472.1
Ddr1
discoidin domain receptor family, member 1
chr16_-_10543028 3.482 ENSMUST00000184863.1
ENSMUST00000038281.5
Dexi

dexamethasone-induced transcript

chr17_-_47016956 3.464 ENSMUST00000165525.1
Gm16494
predicted gene 16494
chr1_-_82586781 3.444 ENSMUST00000087050.5
Col4a4
collagen, type IV, alpha 4
chr19_+_5088534 3.433 ENSMUST00000025811.4
Yif1a
Yip1 interacting factor homolog A (S. cerevisiae)
chr3_+_156562141 3.413 ENSMUST00000175773.1
Negr1
neuronal growth regulator 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
10.5 31.5 GO:1902460 transforming growth factor beta activation(GO:0036363) regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
9.3 9.3 GO:1905072 cardiac jelly development(GO:1905072)
8.6 42.9 GO:0070327 thyroid hormone transport(GO:0070327)
5.6 22.5 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
5.4 5.4 GO:0003134 BMP signaling pathway involved in heart induction(GO:0003130) endodermal-mesodermal cell signaling(GO:0003133) endodermal-mesodermal cell signaling involved in heart induction(GO:0003134)
4.9 14.6 GO:0038095 positive regulation of mast cell cytokine production(GO:0032765) Fc-epsilon receptor signaling pathway(GO:0038095)
4.9 24.3 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
4.7 32.7 GO:0010624 regulation of Schwann cell proliferation(GO:0010624)
4.5 13.6 GO:0006553 lysine metabolic process(GO:0006553)
4.0 7.9 GO:0072197 ureter morphogenesis(GO:0072197)
3.6 21.5 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
3.6 10.7 GO:0090425 hepatocyte cell migration(GO:0002194) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
3.3 10.0 GO:0048687 positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691)
3.0 6.1 GO:0034759 regulation of iron ion transport(GO:0034756) regulation of iron ion transmembrane transport(GO:0034759)
3.0 9.1 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
2.7 8.2 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
2.6 7.9 GO:0002030 inhibitory G-protein coupled receptor phosphorylation(GO:0002030)
2.6 10.3 GO:0000255 allantoin metabolic process(GO:0000255)
2.5 17.7 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
2.5 10.0 GO:0006982 response to lipid hydroperoxide(GO:0006982) cellular response to lipid hydroperoxide(GO:0071449)
2.5 7.5 GO:1901079 positive regulation of relaxation of muscle(GO:1901079)
2.5 27.4 GO:0015721 bile acid and bile salt transport(GO:0015721)
2.4 4.8 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
2.3 7.0 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
2.3 9.1 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
2.2 15.1 GO:0021847 ventricular zone neuroblast division(GO:0021847)
2.2 6.5 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
2.1 2.1 GO:0090259 regulation of retinal ganglion cell axon guidance(GO:0090259)
2.0 10.1 GO:0060591 chondroblast differentiation(GO:0060591)
2.0 6.0 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
1.9 9.6 GO:1903609 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
1.9 5.7 GO:0097350 neutrophil clearance(GO:0097350)
1.9 11.3 GO:0032196 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529) transposition(GO:0032196)
1.9 5.6 GO:0071579 regulation of zinc ion transport(GO:0071579)
1.9 1.9 GO:0003219 cardiac right ventricle formation(GO:0003219)
1.9 9.3 GO:0021905 pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918) sensory neuron migration(GO:1904937)
1.7 15.7 GO:0048251 elastic fiber assembly(GO:0048251)
1.7 5.2 GO:0019343 cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344)
1.6 1.6 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
1.5 4.6 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
1.5 9.1 GO:0097473 cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
1.5 3.0 GO:0048014 Tie signaling pathway(GO:0048014)
1.4 4.3 GO:0030210 heparin biosynthetic process(GO:0030210)
1.4 1.4 GO:0003162 atrioventricular node development(GO:0003162)
1.4 4.3 GO:0035928 rRNA import into mitochondrion(GO:0035928)
1.4 8.5 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
1.4 4.2 GO:0060648 mammary gland bud morphogenesis(GO:0060648) negative regulation of determination of dorsal identity(GO:2000016)
1.3 7.9 GO:0032346 positive regulation of aldosterone metabolic process(GO:0032346) positive regulation of aldosterone biosynthetic process(GO:0032349)
1.3 6.6 GO:0052428 modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
1.3 5.2 GO:0032804 negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804) dibasic protein processing(GO:0090472)
1.3 15.5 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
1.3 3.9 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)
1.3 6.3 GO:0051365 cellular response to potassium ion starvation(GO:0051365)
1.3 3.8 GO:0003057 regulation of the force of heart contraction by chemical signal(GO:0003057)
1.3 18.8 GO:0035994 response to muscle stretch(GO:0035994)
1.2 5.0 GO:1902724 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397) positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
1.2 13.6 GO:0061032 visceral serous pericardium development(GO:0061032)
1.2 4.9 GO:1903236 regulation of leukocyte tethering or rolling(GO:1903236) negative regulation of leukocyte tethering or rolling(GO:1903237)
1.2 2.4 GO:2000282 regulation of cellular amino acid biosynthetic process(GO:2000282)
1.2 2.4 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
1.2 11.6 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
1.2 5.8 GO:1903181 regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181)
1.1 2.3 GO:0035622 intrahepatic bile duct development(GO:0035622)
1.1 2.2 GO:0045168 cell-cell signaling involved in cell fate commitment(GO:0045168)
1.1 3.3 GO:0018199 peptidyl-glutamine modification(GO:0018199)
1.1 4.4 GO:0002484 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway(GO:0002484) antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent(GO:0002485)
1.1 5.4 GO:0042891 antibiotic transport(GO:0042891) dipeptide transport(GO:0042938)
1.1 5.4 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
1.1 3.2 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
1.1 4.2 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
1.0 3.1 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
1.0 4.0 GO:0033030 negative regulation of neutrophil apoptotic process(GO:0033030)
1.0 1.0 GO:0097278 complement-dependent cytotoxicity(GO:0097278)
1.0 2.9 GO:0036118 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
1.0 3.9 GO:0099527 postsynapse to nucleus signaling pathway(GO:0099527)
1.0 3.9 GO:2000110 protein sialylation(GO:1990743) negative regulation of macrophage apoptotic process(GO:2000110)
0.9 2.8 GO:1902524 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354) positive regulation of protein K48-linked ubiquitination(GO:1902524)
0.9 1.9 GO:0070343 white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350)
0.9 3.7 GO:0045950 negative regulation of mitotic recombination(GO:0045950)
0.9 6.5 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.9 10.2 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.9 4.6 GO:0042045 epithelial fluid transport(GO:0042045)
0.9 3.7 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.9 1.8 GO:0048682 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.9 1.8 GO:0072138 mesenchymal cell proliferation involved in ureteric bud development(GO:0072138)
0.9 10.9 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.9 7.3 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.9 18.0 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.9 0.9 GO:2000468 regulation of peroxidase activity(GO:2000468)
0.9 3.5 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.9 6.0 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.9 1.7 GO:1902071 regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.9 1.7 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.8 2.5 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.8 4.1 GO:1905169 protein localization to phagocytic vesicle(GO:1905161) regulation of protein localization to phagocytic vesicle(GO:1905169) positive regulation of protein localization to phagocytic vesicle(GO:1905171)
0.8 0.8 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.8 4.8 GO:0070100 negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.8 7.8 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.7 3.0 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.7 4.4 GO:0098707 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.7 3.7 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.7 5.8 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.7 5.0 GO:0016584 nucleosome positioning(GO:0016584)
0.7 1.4 GO:0048520 positive regulation of behavior(GO:0048520)
0.7 1.4 GO:1903596 regulation of gap junction assembly(GO:1903596)
0.7 2.0 GO:0035964 COPI-coated vesicle budding(GO:0035964)
0.7 8.7 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.7 2.7 GO:0060265 positive regulation of respiratory burst involved in inflammatory response(GO:0060265)
0.7 2.7 GO:0061739 protein lipidation involved in autophagosome assembly(GO:0061739)
0.6 1.9 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.6 0.6 GO:0021593 rhombomere morphogenesis(GO:0021593)
0.6 6.2 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.6 8.0 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.6 3.7 GO:1902998 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.6 4.3 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.6 2.4 GO:0072272 proximal/distal pattern formation involved in metanephric nephron development(GO:0072272)
0.6 2.4 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.6 1.8 GO:0060596 regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003256) mammary placode formation(GO:0060596)
0.6 3.0 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.6 0.6 GO:0072180 mesonephric duct development(GO:0072177) mesonephric duct morphogenesis(GO:0072180)
0.6 1.8 GO:0070428 granuloma formation(GO:0002432) toll-like receptor 5 signaling pathway(GO:0034146) regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428) regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070432)
0.6 1.8 GO:0035905 ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.6 2.3 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.6 11.0 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.6 2.3 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.6 2.9 GO:0048539 bone marrow development(GO:0048539)
0.6 5.1 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.6 1.7 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.6 2.8 GO:0034421 post-translational protein acetylation(GO:0034421)
0.5 3.2 GO:0090037 positive regulation of protein kinase C signaling(GO:0090037)
0.5 1.6 GO:0071500 cellular response to nitrosative stress(GO:0071500)
0.5 1.6 GO:0035811 negative regulation of urine volume(GO:0035811)
0.5 1.6 GO:0006592 ornithine biosynthetic process(GO:0006592)
0.5 3.1 GO:0019896 axonal transport of mitochondrion(GO:0019896)
0.5 5.2 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.5 2.1 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.5 1.0 GO:0070885 negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.5 1.5 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.5 3.0 GO:0016266 O-glycan processing(GO:0016266)
0.5 1.5 GO:0072092 ureteric bud invasion(GO:0072092)
0.5 1.5 GO:0071873 response to norepinephrine(GO:0071873)
0.5 2.4 GO:1904721 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.5 1.5 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.5 4.3 GO:0071285 cellular response to lithium ion(GO:0071285)
0.5 7.5 GO:0060134 prepulse inhibition(GO:0060134)
0.5 2.3 GO:2001286 regulation of caveolin-mediated endocytosis(GO:2001286)
0.5 1.4 GO:0051660 establishment of centrosome localization(GO:0051660)
0.4 0.4 GO:0048550 negative regulation of pinocytosis(GO:0048550)
0.4 3.4 GO:0032836 glomerular basement membrane development(GO:0032836)
0.4 12.2 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866)
0.4 1.3 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.4 4.2 GO:0002118 aggressive behavior(GO:0002118)
0.4 1.7 GO:0072592 oxygen metabolic process(GO:0072592)
0.4 6.4 GO:0045792 negative regulation of cell size(GO:0045792)
0.4 0.8 GO:0010755 regulation of plasminogen activation(GO:0010755)
0.4 1.6 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.4 2.7 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.4 1.2 GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.4 1.2 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.4 2.7 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.4 3.1 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.4 5.3 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.4 0.8 GO:0035990 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992) sclerotome development(GO:0061056)
0.4 2.3 GO:2001170 negative regulation of ATP biosynthetic process(GO:2001170)
0.4 1.9 GO:0050912 detection of chemical stimulus involved in sensory perception(GO:0050907) detection of chemical stimulus involved in sensory perception of taste(GO:0050912)
0.3 2.1 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.3 2.7 GO:0048149 behavioral response to ethanol(GO:0048149)
0.3 2.0 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.3 4.0 GO:0048194 Golgi vesicle budding(GO:0048194)
0.3 8.1 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.3 8.1 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.3 2.7 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.3 4.0 GO:0072112 renal filtration cell differentiation(GO:0061318) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.3 0.6 GO:0048859 formation of anatomical boundary(GO:0048859)
0.3 1.0 GO:1903406 regulation of sodium:potassium-exchanging ATPase activity(GO:1903406)
0.3 1.0 GO:0045054 constitutive secretory pathway(GO:0045054)
0.3 1.6 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.3 1.3 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.3 1.3 GO:0042822 pyridoxal phosphate metabolic process(GO:0042822)
0.3 0.3 GO:0097212 lysosomal membrane organization(GO:0097212)
0.3 4.3 GO:0097435 fibril organization(GO:0097435)
0.3 2.2 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.3 2.5 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.3 3.1 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070)
0.3 0.6 GO:0051593 response to folic acid(GO:0051593)
0.3 2.7 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.3 9.3 GO:0007520 myoblast fusion(GO:0007520)
0.3 2.7 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.3 9.8 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.3 3.8 GO:0045199 maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.3 1.2 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.3 1.4 GO:0070303 negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of JNK cascade(GO:0046329) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303)
0.3 2.5 GO:0035898 parathyroid hormone secretion(GO:0035898)
0.3 1.1 GO:0043973 histone H3-K4 acetylation(GO:0043973)
0.3 2.0 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.3 1.9 GO:0045002 double-strand break repair via single-strand annealing(GO:0045002)
0.3 1.4 GO:0006689 ganglioside catabolic process(GO:0006689)
0.3 0.8 GO:0048369 neural plate mediolateral regionalization(GO:0021998) mesoderm structural organization(GO:0048338) paraxial mesoderm structural organization(GO:0048352) lateral mesoderm morphogenesis(GO:0048369) lateral mesoderm formation(GO:0048370) lateral mesodermal cell differentiation(GO:0048371) lateral mesodermal cell fate commitment(GO:0048372) lateral mesodermal cell fate specification(GO:0048377) regulation of lateral mesodermal cell fate specification(GO:0048378) regulation of cardiac ventricle development(GO:1904412) positive regulation of cardiac ventricle development(GO:1904414)
0.3 0.8 GO:1902512 positive regulation of apoptotic DNA fragmentation(GO:1902512) positive regulation of DNA catabolic process(GO:1903626)
0.3 2.9 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.3 1.6 GO:0036089 cleavage furrow formation(GO:0036089)
0.3 1.6 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.3 6.1 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.3 0.8 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.3 6.6 GO:0001569 patterning of blood vessels(GO:0001569)
0.3 1.6 GO:0031125 rRNA 3'-end processing(GO:0031125)
0.3 2.6 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.3 3.1 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.3 1.0 GO:0032769 negative regulation of monooxygenase activity(GO:0032769) negative regulation of nitric-oxide synthase activity(GO:0051001)
0.3 1.0 GO:0070166 enamel mineralization(GO:0070166)
0.2 1.2 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.2 2.7 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.2 8.1 GO:0031365 N-terminal protein amino acid modification(GO:0031365)
0.2 5.4 GO:0035036 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036)
0.2 0.5 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.2 0.2 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.2 1.0 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.2 1.2 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372)
0.2 0.5 GO:0006842 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.2 1.4 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.2 0.9 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.2 1.2 GO:0007256 activation of JNKK activity(GO:0007256)
0.2 1.6 GO:0046549 phenol-containing compound catabolic process(GO:0019336) retinal cone cell development(GO:0046549)
0.2 3.9 GO:0002115 store-operated calcium entry(GO:0002115)
0.2 0.7 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.2 3.6 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.2 2.5 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.2 2.7 GO:2001273 regulation of glucose import in response to insulin stimulus(GO:2001273)
0.2 2.2 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.2 0.4 GO:0021506 anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995)
0.2 6.6 GO:0060351 cartilage development involved in endochondral bone morphogenesis(GO:0060351)
0.2 6.4 GO:0000132 establishment of mitotic spindle orientation(GO:0000132)
0.2 5.6 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.2 0.6 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.2 1.8 GO:0051255 spindle midzone assembly(GO:0051255) mitotic spindle midzone assembly(GO:0051256)
0.2 12.9 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.2 0.4 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.2 1.4 GO:0006105 succinate metabolic process(GO:0006105)
0.2 1.0 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.2 1.0 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.2 0.8 GO:0045896 regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.2 0.8 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.2 0.4 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.2 1.4 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.2 3.2 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.2 1.9 GO:0045624 positive regulation of T-helper cell differentiation(GO:0045624)
0.2 2.5 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.2 1.9 GO:0090527 actin filament reorganization(GO:0090527)
0.2 2.1 GO:0070995 NADPH oxidation(GO:0070995)
0.2 0.8 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.2 0.2 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.2 2.6 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.2 1.1 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.2 0.7 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.2 3.7 GO:0015936 coenzyme A metabolic process(GO:0015936)
0.2 2.4 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.2 2.7 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
0.2 1.4 GO:0046415 urate metabolic process(GO:0046415)
0.2 5.2 GO:0045026 plasma membrane fusion(GO:0045026)
0.2 1.3 GO:0010820 positive regulation of T cell chemotaxis(GO:0010820)
0.2 3.4 GO:0050434 positive regulation of viral transcription(GO:0050434)
0.2 6.1 GO:0060325 face morphogenesis(GO:0060325)
0.2 3.8 GO:0090083 regulation of inclusion body assembly(GO:0090083)
0.2 0.3 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.2 1.4 GO:0006013 mannose metabolic process(GO:0006013)
0.2 1.9 GO:0046051 UTP metabolic process(GO:0046051)
0.2 5.6 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.2 0.9 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.2 2.5 GO:0008206 bile acid metabolic process(GO:0008206)
0.2 8.3 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.2 1.4 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.2 1.9 GO:0016322 neuron remodeling(GO:0016322)
0.2 0.6 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.2 0.6 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.1 0.6 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 4.6 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.1 3.8 GO:0016578 histone deubiquitination(GO:0016578)
0.1 1.7 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.1 0.7 GO:0016601 Rac protein signal transduction(GO:0016601)
0.1 2.3 GO:0060259 regulation of feeding behavior(GO:0060259)
0.1 5.2 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.1 0.7 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.1 2.8 GO:0030032 lamellipodium assembly(GO:0030032)
0.1 1.7 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.1 1.1 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.1 5.9 GO:0006023 aminoglycan biosynthetic process(GO:0006023)
0.1 0.5 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.1 0.8 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.1 4.0 GO:0007566 embryo implantation(GO:0007566)
0.1 0.3 GO:1901420 negative regulation of vitamin D biosynthetic process(GO:0010957) vitamin D biosynthetic process(GO:0042368) negative regulation of vitamin metabolic process(GO:0046137) regulation of vitamin D biosynthetic process(GO:0060556) negative regulation of response to alcohol(GO:1901420)
0.1 0.5 GO:0015744 succinate transport(GO:0015744)
0.1 0.6 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.1 2.3 GO:0050873 brown fat cell differentiation(GO:0050873)
0.1 0.6 GO:2000427 eosinophil chemotaxis(GO:0048245) regulation of apoptotic cell clearance(GO:2000425) positive regulation of apoptotic cell clearance(GO:2000427)
0.1 6.4 GO:0001676 long-chain fatty acid metabolic process(GO:0001676)
0.1 0.4 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.1 1.0 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.1 1.2 GO:0046548 retinal rod cell development(GO:0046548)
0.1 1.1 GO:0035428 hexose transmembrane transport(GO:0035428)
0.1 2.8 GO:0014904 myotube cell development(GO:0014904)
0.1 0.5 GO:0043461 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.1 4.5 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.1 2.0 GO:0000731 DNA synthesis involved in DNA repair(GO:0000731)
0.1 7.9 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.1 0.8 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.1 2.2 GO:0048266 behavioral response to pain(GO:0048266)
0.1 1.9 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 2.2 GO:0044458 motile cilium assembly(GO:0044458)
0.1 1.5 GO:0048712 negative regulation of astrocyte differentiation(GO:0048712)
0.1 0.4 GO:1903286 regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288)
0.1 1.0 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.1 1.6 GO:0048240 sperm capacitation(GO:0048240)
0.1 0.4 GO:0010884 positive regulation of lipid storage(GO:0010884)
0.1 0.4 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.1 0.5 GO:0031507 heterochromatin assembly(GO:0031507)
0.1 0.9 GO:1904667 negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.1 0.8 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.1 0.4 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.1 0.3 GO:1903624 regulation of apoptotic DNA fragmentation(GO:1902510) regulation of DNA catabolic process(GO:1903624)
0.1 1.1 GO:0007413 axonal fasciculation(GO:0007413)
0.1 2.4 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 1.5 GO:0035272 exocrine system development(GO:0035272)
0.1 0.2 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.1 0.2 GO:1901096 regulation of autophagosome maturation(GO:1901096)
0.1 1.3 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.1 0.8 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.4 GO:2000465 regulation of glycogen (starch) synthase activity(GO:2000465)
0.1 0.5 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 0.4 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.1 0.9 GO:0043277 apoptotic cell clearance(GO:0043277)
0.1 0.4 GO:0010566 regulation of ketone biosynthetic process(GO:0010566)
0.1 1.2 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.1 0.5 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.1 1.5 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.1 9.4 GO:0007160 cell-matrix adhesion(GO:0007160)
0.1 4.9 GO:0009408 response to heat(GO:0009408)
0.1 2.9 GO:0070206 protein trimerization(GO:0070206)
0.1 0.5 GO:0031086 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 0.1 GO:0051661 maintenance of centrosome location(GO:0051661)
0.1 0.5 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.1 0.3 GO:0046709 IDP metabolic process(GO:0046707) IDP catabolic process(GO:0046709)
0.1 0.2 GO:1904049 regulation of spontaneous neurotransmitter secretion(GO:1904048) negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.1 1.1 GO:0000338 protein deneddylation(GO:0000338)
0.1 0.4 GO:0050995 negative regulation of lipid catabolic process(GO:0050995)
0.1 2.1 GO:0006940 regulation of smooth muscle contraction(GO:0006940)
0.1 1.2 GO:0061098 positive regulation of protein tyrosine kinase activity(GO:0061098)
0.1 1.0 GO:0042993 positive regulation of transcription factor import into nucleus(GO:0042993)
0.1 1.2 GO:0072337 modified amino acid transport(GO:0072337)
0.1 1.6 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.1 0.3 GO:0006477 protein sulfation(GO:0006477)
0.1 4.7 GO:0001889 liver development(GO:0001889)
0.1 2.6 GO:0010038 response to metal ion(GO:0010038)
0.1 0.5 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.1 0.5 GO:0097369 sodium ion import(GO:0097369)
0.1 0.3 GO:0014823 response to activity(GO:0014823)
0.1 0.3 GO:0001516 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.1 4.0 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.1 0.9 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.2 GO:0006953 acute-phase response(GO:0006953)
0.0 1.2 GO:0090102 cochlea development(GO:0090102)
0.0 0.7 GO:0046324 regulation of glucose import(GO:0046324)
0.0 1.0 GO:0006298 mismatch repair(GO:0006298)
0.0 3.3 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.5 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 0.6 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.3 GO:0060539 diaphragm development(GO:0060539)
0.0 0.3 GO:0055088 lipid homeostasis(GO:0055088)
0.0 0.4 GO:0070475 rRNA base methylation(GO:0070475)
0.0 1.4 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.2 GO:0042360 vitamin E metabolic process(GO:0042360)
0.0 1.1 GO:0051443 positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.0 1.0 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 1.0 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.4 GO:0042255 ribosome assembly(GO:0042255)
0.0 0.2 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.5 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0 0.3 GO:0050850 positive regulation of calcium-mediated signaling(GO:0050850)
0.0 0.4 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.3 GO:0036506 maintenance of unfolded protein(GO:0036506) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.0 0.3 GO:0015693 magnesium ion transport(GO:0015693)
0.0 2.4 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.5 GO:0044065 regulation of respiratory system process(GO:0044065)
0.0 0.7 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 0.2 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.3 GO:0021542 dentate gyrus development(GO:0021542)
0.0 0.3 GO:0019884 antigen processing and presentation of exogenous antigen(GO:0019884)
0.0 0.3 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.0 0.7 GO:0048286 lung alveolus development(GO:0048286)
0.0 0.1 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 1.1 GO:0048663 neuron fate commitment(GO:0048663)
0.0 0.1 GO:0060613 fat pad development(GO:0060613)
0.0 1.6 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.4 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.9 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.6 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.0 0.9 GO:0008542 visual learning(GO:0008542)
0.0 0.4 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.1 GO:0090282 trophectodermal cellular morphogenesis(GO:0001831) trophectodermal cell proliferation(GO:0001834) positive regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071931) positive regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0090282)
0.0 0.2 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.3 GO:0030500 regulation of bone mineralization(GO:0030500)
0.0 1.1 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 1.0 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.0 0.7 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.0 0.3 GO:0048146 positive regulation of fibroblast proliferation(GO:0048146)
0.0 1.9 GO:0009615 response to virus(GO:0009615)
0.0 0.2 GO:0070200 establishment of protein localization to telomere(GO:0070200)
0.0 0.8 GO:0007631 feeding behavior(GO:0007631)
0.0 0.3 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.2 GO:0006582 melanin metabolic process(GO:0006582) melanin biosynthetic process(GO:0042438)
0.0 1.7 GO:0051028 mRNA transport(GO:0051028)
0.0 0.2 GO:0043153 photoperiodism(GO:0009648) entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.7 GO:0009060 aerobic respiration(GO:0009060)
0.0 0.5 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.3 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.2 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.0 GO:0061300 cerebellum vasculature development(GO:0061300)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
8.2 32.7 GO:0097450 astrocyte end-foot(GO:0097450)
3.3 10.0 GO:0071953 elastic fiber(GO:0071953)
2.7 16.3 GO:0035976 AP1 complex(GO:0035976)
2.3 7.0 GO:0005588 collagen type V trimer(GO:0005588)
1.9 7.5 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
1.8 3.6 GO:0036488 CHOP-C/EBP complex(GO:0036488)
1.7 5.1 GO:0030934 collagen type XII trimer(GO:0005595) anchoring collagen complex(GO:0030934)
1.6 6.5 GO:0014802 terminal cisterna(GO:0014802)
1.5 4.6 GO:0031088 platelet dense granule membrane(GO:0031088)
1.5 7.5 GO:0033093 Weibel-Palade body(GO:0033093)
1.2 15.0 GO:0042612 MHC class I protein complex(GO:0042612)
1.2 6.2 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
1.1 4.2 GO:0032280 symmetric synapse(GO:0032280)
0.7 2.9 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.7 9.5 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.7 3.4 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.6 4.4 GO:0005638 lamin filament(GO:0005638)
0.6 6.4 GO:0031931 TORC1 complex(GO:0031931)
0.6 4.4 GO:0033391 chromatoid body(GO:0033391)
0.6 4.4 GO:0097433 dense body(GO:0097433)
0.5 9.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.5 3.7 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.5 12.1 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.5 1.6 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.5 9.8 GO:0005605 basal lamina(GO:0005605)
0.5 1.9 GO:0005594 collagen type IX trimer(GO:0005594)
0.5 5.6 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.5 7.3 GO:0005614 interstitial matrix(GO:0005614)
0.4 1.7 GO:0032021 NELF complex(GO:0032021)
0.4 4.2 GO:0032591 dendritic spine membrane(GO:0032591)
0.4 14.1 GO:0051233 spindle midzone(GO:0051233)
0.4 5.4 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.4 2.0 GO:0001652 granular component(GO:0001652)
0.4 3.6 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.4 3.9 GO:0000138 Golgi trans cisterna(GO:0000138)
0.4 4.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.4 5.7 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.4 2.6 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.4 1.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.4 1.4 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.3 36.1 GO:0030175 filopodium(GO:0030175)
0.3 5.2 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.3 0.6 GO:0044299 C-fiber(GO:0044299)
0.3 2.5 GO:0042589 zymogen granule membrane(GO:0042589)
0.3 25.6 GO:0072562 blood microparticle(GO:0072562)
0.3 2.8 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.3 1.5 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.3 1.2 GO:0035189 Rb-E2F complex(GO:0035189)
0.3 0.9 GO:0044753 amphisome(GO:0044753)
0.3 1.4 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.3 5.9 GO:0000788 nuclear nucleosome(GO:0000788)
0.3 54.7 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.3 11.2 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.3 5.7 GO:0043657 host(GO:0018995) host cell part(GO:0033643) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.3 1.5 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.2 13.6 GO:0005581 collagen trimer(GO:0005581)
0.2 3.7 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.2 0.7 GO:0016600 flotillin complex(GO:0016600)
0.2 0.9 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.2 3.4 GO:0031083 BLOC-1 complex(GO:0031083)
0.2 1.8 GO:0030478 actin cap(GO:0030478)
0.2 15.2 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.2 1.5 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.2 31.9 GO:0031012 extracellular matrix(GO:0031012)
0.2 2.4 GO:0061700 GATOR2 complex(GO:0061700)
0.2 1.4 GO:0014704 intercalated disc(GO:0014704)
0.2 1.2 GO:0042588 zymogen granule(GO:0042588)
0.2 8.2 GO:0031985 Golgi cisterna(GO:0031985)
0.2 2.7 GO:0005662 DNA replication factor A complex(GO:0005662)
0.2 1.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.2 1.4 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.2 1.2 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.2 1.2 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.2 1.0 GO:0005859 muscle myosin complex(GO:0005859)
0.2 1.9 GO:0031528 microvillus membrane(GO:0031528)
0.2 1.0 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.2 1.0 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.2 16.7 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.2 1.1 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.2 6.2 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.2 1.4 GO:0030991 intraciliary transport particle A(GO:0030991)
0.2 2.4 GO:0097228 sperm principal piece(GO:0097228)
0.1 1.0 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 19.2 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.1 0.4 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.1 25.9 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 0.7 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 5.3 GO:0005902 microvillus(GO:0005902)
0.1 2.2 GO:0097225 sperm midpiece(GO:0097225)
0.1 1.3 GO:0022626 cytosolic ribosome(GO:0022626)
0.1 7.7 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 6.0 GO:0045177 apical part of cell(GO:0045177)
0.1 2.2 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.4 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.1 1.0 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.1 0.6 GO:0033180 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178) proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 1.3 GO:0070938 contractile ring(GO:0070938)
0.1 6.8 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 3.0 GO:0030667 secretory granule membrane(GO:0030667)
0.1 3.9 GO:0016592 mediator complex(GO:0016592)
0.1 0.2 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.1 3.0 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 3.3 GO:0001917 photoreceptor inner segment(GO:0001917)
0.1 0.3 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.1 2.7 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 0.6 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.1 1.5 GO:0031143 pseudopodium(GO:0031143)
0.1 9.7 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 0.6 GO:0030914 STAGA complex(GO:0030914)
0.1 1.3 GO:0016589 NURF complex(GO:0016589)
0.1 1.6 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 3.1 GO:0000786 nucleosome(GO:0000786)
0.1 5.8 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.1 5.3 GO:0005901 caveola(GO:0005901)
0.1 0.3 GO:0031021 interphase microtubule organizing center(GO:0031021)
0.1 15.1 GO:0005769 early endosome(GO:0005769)
0.1 54.0 GO:0005615 extracellular space(GO:0005615)
0.1 26.7 GO:0005925 focal adhesion(GO:0005925)
0.1 0.3 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 0.4 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.1 1.0 GO:0017119 Golgi transport complex(GO:0017119)
0.1 1.7 GO:0031201 SNARE complex(GO:0031201)
0.1 0.4 GO:0061574 ASAP complex(GO:0061574)
0.1 2.8 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1 1.0 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 0.8 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 1.0 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 2.1 GO:0097546 ciliary base(GO:0097546)
0.1 1.1 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 0.3 GO:0070876 SOSS complex(GO:0070876)
0.1 11.3 GO:0005667 transcription factor complex(GO:0005667)
0.1 0.2 GO:0071817 MMXD complex(GO:0071817)
0.1 0.3 GO:0072487 MSL complex(GO:0072487)
0.1 0.5 GO:0005677 chromatin silencing complex(GO:0005677)
0.1 2.0 GO:0031594 neuromuscular junction(GO:0031594)
0.0 1.0 GO:0097440 apical dendrite(GO:0097440)
0.0 1.9 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.3 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.1 GO:0070557 PCNA-p21 complex(GO:0070557)
0.0 0.6 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 1.2 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.4 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.2 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.0 0.3 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 1.6 GO:0005871 kinesin complex(GO:0005871)
0.0 0.5 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 3.1 GO:0000922 spindle pole(GO:0000922)
0.0 1.1 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.8 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 1.8 GO:0010008 endosome membrane(GO:0010008)
0.0 0.8 GO:0005657 replication fork(GO:0005657)
0.0 1.4 GO:0031519 PcG protein complex(GO:0031519)
0.0 1.1 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.6 GO:0035861 site of double-strand break(GO:0035861)
0.0 1.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.5 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 1.0 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.4 GO:0005798 Golgi-associated vesicle(GO:0005798)
0.0 1.3 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 5.5 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 15.8 GO:0005739 mitochondrion(GO:0005739)
0.0 0.7 GO:0012506 vesicle membrane(GO:0012506)
0.0 0.2 GO:0035327 transcriptionally active chromatin(GO:0035327)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
7.7 23.1 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
7.0 28.1 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
6.1 24.3 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
4.8 42.9 GO:0070324 thyroid hormone binding(GO:0070324)
3.6 14.3 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
3.3 13.3 GO:0008131 primary amine oxidase activity(GO:0008131)
3.1 12.3 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
2.8 11.3 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
2.7 8.0 GO:0004686 elongation factor-2 kinase activity(GO:0004686)
2.5 22.4 GO:0036122 BMP binding(GO:0036122)
2.0 10.0 GO:0005030 neurotrophin receptor activity(GO:0005030)
1.9 11.6 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
1.9 9.6 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
1.8 5.4 GO:0042936 dipeptide transporter activity(GO:0042936)
1.7 5.2 GO:0098809 nitrite reductase activity(GO:0098809)
1.5 4.6 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
1.5 9.1 GO:0045545 syndecan binding(GO:0045545)
1.5 5.8 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
1.4 31.5 GO:0050431 transforming growth factor beta binding(GO:0050431)
1.3 3.8 GO:0004517 nitric-oxide synthase activity(GO:0004517)
1.2 12.4 GO:0070700 BMP receptor binding(GO:0070700)
1.2 4.9 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
1.2 14.3 GO:0050693 LBD domain binding(GO:0050693)
1.1 6.5 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
1.0 2.1 GO:0070052 collagen V binding(GO:0070052)
1.0 9.3 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
1.0 22.5 GO:0005520 insulin-like growth factor binding(GO:0005520)
1.0 4.9 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
1.0 2.9 GO:0004415 hyalurononglucosaminidase activity(GO:0004415) hyaluronan synthase activity(GO:0050501)
0.9 6.6 GO:0001849 complement component C1q binding(GO:0001849)
0.9 3.7 GO:0038049 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.9 2.7 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.9 3.5 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.9 11.2 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.9 4.3 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.8 4.2 GO:1990239 steroid hormone binding(GO:1990239)
0.8 3.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.8 4.9 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004) PH domain binding(GO:0042731)
0.8 11.8 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.8 3.9 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.7 6.5 GO:0019865 immunoglobulin binding(GO:0019865)
0.7 4.3 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.7 8.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.7 6.3 GO:0032564 dATP binding(GO:0032564)
0.7 8.9 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.7 2.0 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936)
0.7 3.3 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.6 3.2 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.6 1.9 GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
0.6 24.9 GO:0070412 R-SMAD binding(GO:0070412)
0.6 2.5 GO:0008410 CoA-transferase activity(GO:0008410)
0.6 4.4 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.6 3.0 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.6 5.2 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.6 2.3 GO:0043546 molybdenum ion binding(GO:0030151) molybdopterin cofactor binding(GO:0043546)
0.6 4.0 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.6 6.1 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.6 5.0 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.5 2.2 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.5 1.6 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.5 9.2 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.5 4.2 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.5 1.6 GO:0017084 glutamate 5-kinase activity(GO:0004349) glutamate-5-semialdehyde dehydrogenase activity(GO:0004350) delta1-pyrroline-5-carboxylate synthetase activity(GO:0017084) amino acid kinase activity(GO:0019202)
0.5 3.6 GO:0015288 porin activity(GO:0015288)
0.5 5.7 GO:0032036 myosin heavy chain binding(GO:0032036)
0.5 8.1 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.5 1.5 GO:0019966 C-X-C chemokine binding(GO:0019958) interleukin-1 binding(GO:0019966) tumor necrosis factor binding(GO:0043120)
0.5 3.0 GO:0035184 histone threonine kinase activity(GO:0035184)
0.5 3.5 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.5 2.5 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.5 1.4 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177) 3 iron, 4 sulfur cluster binding(GO:0051538)
0.5 3.8 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.5 3.8 GO:0048495 Roundabout binding(GO:0048495)
0.5 6.1 GO:0050897 cobalt ion binding(GO:0050897)
0.5 3.2 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.5 1.8 GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038)
0.5 2.3 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.5 2.7 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.5 1.8 GO:0048408 epidermal growth factor binding(GO:0048408)
0.4 4.9 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.4 4.4 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.4 10.0 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.4 9.2 GO:0070182 DNA polymerase binding(GO:0070182)
0.4 2.5 GO:0009374 biotin binding(GO:0009374)
0.4 8.3 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.4 5.4 GO:0005522 profilin binding(GO:0005522)
0.4 0.8 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.4 2.4 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.4 1.6 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.4 3.6 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.4 3.2 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.4 3.6 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.4 2.4 GO:0070728 leucine binding(GO:0070728)
0.4 3.0 GO:0005540 hyaluronic acid binding(GO:0005540)
0.4 1.5 GO:2001069 glycogen binding(GO:2001069)
0.4 11.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.4 5.2 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.4 4.1 GO:0008430 selenium binding(GO:0008430)
0.4 2.6 GO:0015929 hexosaminidase activity(GO:0015929)
0.4 1.5 GO:0051425 PTB domain binding(GO:0051425)
0.4 2.5 GO:0001515 opioid peptide activity(GO:0001515)
0.4 11.5 GO:0001223 transcription coactivator binding(GO:0001223)
0.4 3.9 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.4 1.1 GO:0008527 taste receptor activity(GO:0008527)
0.3 1.7 GO:0071532 ankyrin repeat binding(GO:0071532)
0.3 2.4 GO:0015925 galactosidase activity(GO:0015925)
0.3 1.0 GO:0019002 GMP binding(GO:0019002)
0.3 2.1 GO:0050786 RAGE receptor binding(GO:0050786)
0.3 1.4 GO:0070573 tripeptidyl-peptidase activity(GO:0008240) metallodipeptidase activity(GO:0070573)
0.3 11.3 GO:0042805 actinin binding(GO:0042805)
0.3 1.7 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.3 33.8 GO:0005178 integrin binding(GO:0005178)
0.3 3.7 GO:0044548 S100 protein binding(GO:0044548)
0.3 1.3 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.3 1.3 GO:0033883 pyridoxal phosphatase activity(GO:0033883)
0.3 11.3 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.3 1.2 GO:0008948 oxaloacetate decarboxylase activity(GO:0008948)
0.3 8.6 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.3 3.4 GO:0030957 Tat protein binding(GO:0030957)
0.3 1.8 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.3 4.2 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.3 2.4 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.3 1.2 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.3 0.9 GO:0034211 GTP-dependent protein kinase activity(GO:0034211)
0.3 3.6 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013)
0.3 17.6 GO:0019003 GDP binding(GO:0019003)
0.3 0.8 GO:0098821 BMP receptor activity(GO:0098821)
0.3 0.8 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.3 0.8 GO:0031896 alpha-1A adrenergic receptor binding(GO:0031691) alpha-1B adrenergic receptor binding(GO:0031692) follicle-stimulating hormone receptor binding(GO:0031762) V2 vasopressin receptor binding(GO:0031896)
0.3 7.5 GO:0005504 fatty acid binding(GO:0005504)
0.3 7.8 GO:0019789 SUMO transferase activity(GO:0019789)
0.3 0.8 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.3 12.1 GO:0019838 growth factor binding(GO:0019838)
0.3 2.8 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.3 1.8 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.3 6.5 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.3 6.5 GO:0005112 Notch binding(GO:0005112)
0.2 11.7 GO:0005518 collagen binding(GO:0005518)
0.2 6.0 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.2 1.4 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.2 0.7 GO:0050816 phosphothreonine binding(GO:0050816)
0.2 2.3 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
0.2 1.4 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.2 1.8 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.2 0.9 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.2 1.3 GO:0051525 NFAT protein binding(GO:0051525)
0.2 0.9 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.2 3.6 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.2 1.5 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.2 0.6 GO:0004104 cholinesterase activity(GO:0004104) choline binding(GO:0033265)
0.2 0.8 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.2 0.8 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.2 1.2 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.2 1.0 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.2 4.1 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.2 2.7 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.2 1.0 GO:0001224 RNA polymerase II transcription cofactor binding(GO:0001224) RNA polymerase II transcription corepressor binding(GO:0001226)
0.2 0.6 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.2 2.3 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.2 1.9 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.2 0.7 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.2 0.7 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.2 3.4 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.2 0.9 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.2 0.2 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.2 5.4 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.2 0.5 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.2 1.9 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.2 4.5 GO:0070064 proline-rich region binding(GO:0070064)
0.2 3.0 GO:0050811 GABA receptor binding(GO:0050811)
0.2 1.5 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.2 1.6 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.2 1.1 GO:0030274 LIM domain binding(GO:0030274)
0.2 1.0 GO:0005042 netrin receptor activity(GO:0005042)
0.2 0.6 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.2 3.0 GO:0017160 Ral GTPase binding(GO:0017160)
0.2 3.0 GO:0042287 MHC protein binding(GO:0042287)
0.2 1.5 GO:0016406 carnitine O-acyltransferase activity(GO:0016406)
0.1 4.0 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 2.7 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 0.4 GO:0008384 IkappaB kinase activity(GO:0008384)
0.1 0.4 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.1 0.7 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.1 1.8 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 9.6 GO:0005080 protein kinase C binding(GO:0005080)
0.1 1.0 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 0.3 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.1 0.4 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.1 0.8 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 1.0 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.1 8.5 GO:0008201 heparin binding(GO:0008201)
0.1 0.4 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466) very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.1 0.9 GO:0008097 5S rRNA binding(GO:0008097)
0.1 1.4 GO:0042605 peptide antigen binding(GO:0042605)
0.1 1.5 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 1.5 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 0.6 GO:0000213 tRNA-intron endonuclease activity(GO:0000213) endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.1 2.3 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.1 5.4 GO:0005179 hormone activity(GO:0005179)
0.1 1.4 GO:0005537 mannose binding(GO:0005537)
0.1 0.5 GO:0070568 guanylyltransferase activity(GO:0070568)
0.1 0.5 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.1 0.4 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.1 1.1 GO:0015149 glucose transmembrane transporter activity(GO:0005355) hexose transmembrane transporter activity(GO:0015149)
0.1 4.6 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.1 0.9 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.1 1.2 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 2.7 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 7.2 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.1 0.2 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.1 3.2 GO:0017022 myosin binding(GO:0017022)
0.1 3.2 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1 1.8 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 1.8 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 0.5 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 1.5 GO:0051787 misfolded protein binding(GO:0051787)
0.1 1.9 GO:0050699 WW domain binding(GO:0050699)
0.1 0.5 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.1 0.4 GO:0070403 NAD+ binding(GO:0070403)
0.1 0.3 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.1 0.7 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1 2.8 GO:0070888 E-box binding(GO:0070888)
0.1 1.6 GO:0030371 translation repressor activity(GO:0030371)
0.1 0.1 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.1 1.7 GO:0004407 histone deacetylase activity(GO:0004407)
0.1 0.3 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 8.1 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 1.0 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 1.2 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 1.0 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.7 GO:0004536 deoxyribonuclease activity(GO:0004536)
0.0 1.7 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.9 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.3 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.4 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 1.0 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 2.1 GO:0000149 SNARE binding(GO:0000149)
0.0 0.7 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.0 0.8 GO:0008373 sialyltransferase activity(GO:0008373)
0.0 0.7 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.7 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454) histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.5 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.9 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.9 GO:0005507 copper ion binding(GO:0005507)
0.0 0.5 GO:0035591 signaling adaptor activity(GO:0035591)
0.0 0.6 GO:0030506 ankyrin binding(GO:0030506)
0.0 1.8 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.8 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.8 GO:0004180 carboxypeptidase activity(GO:0004180)
0.0 0.1 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol trisphosphate phosphatase activity(GO:0046030)
0.0 0.7 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.9 GO:0016209 antioxidant activity(GO:0016209)
0.0 0.2 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.7 GO:0020037 heme binding(GO:0020037)
0.0 1.4 GO:0002020 protease binding(GO:0002020)
0.0 0.2 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.3 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.2 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.7 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.2 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 1.4 GO:0004519 endonuclease activity(GO:0004519)
0.0 0.3 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.4 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 1.2 GO:0003774 motor activity(GO:0003774)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 3.2 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
1.2 21.1 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
1.1 19.7 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.9 17.0 ST_STAT3_PATHWAY STAT3 Pathway
0.9 6.3 PID_ATF2_PATHWAY ATF-2 transcription factor network
0.8 39.8 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.7 15.6 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.6 9.2 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.6 29.6 SIG_PIP3_SIGNALING_IN_B_LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.6 78.4 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.5 13.0 PID_SHP2_PATHWAY SHP2 signaling
0.5 14.8 PID_VEGFR1_PATHWAY VEGFR1 specific signals
0.4 3.1 ST_PAC1_RECEPTOR_PATHWAY PAC1 Receptor Pathway
0.4 13.0 NABA_COLLAGENS Genes encoding collagen proteins
0.4 6.0 SA_G1_AND_S_PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.4 7.5 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.3 3.8 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.3 24.6 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.3 6.7 PID_S1P_META_PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.3 14.8 PID_CD8_TCR_PATHWAY TCR signaling in naïve CD8+ T cells
0.3 5.8 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.3 9.5 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.3 4.2 PID_IL2_1PATHWAY IL2-mediated signaling events
0.3 1.9 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.3 1.4 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.3 35.5 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.2 2.7 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.2 1.3 PID_S1P_S1P2_PATHWAY S1P2 pathway
0.2 4.3 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.2 5.7 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.2 38.5 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.2 7.6 PID_MET_PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.2 1.4 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.2 3.9 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.2 6.7 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.2 4.9 ST_TUMOR_NECROSIS_FACTOR_PATHWAY Tumor Necrosis Factor Pathway.
0.2 5.1 PID_FAK_PATHWAY Signaling events mediated by focal adhesion kinase
0.2 4.3 PID_FGF_PATHWAY FGF signaling pathway
0.1 6.9 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.1 8.7 PID_CDC42_PATHWAY CDC42 signaling events
0.1 5.4 PID_INSULIN_PATHWAY Insulin Pathway
0.1 1.5 ST_ADRENERGIC Adrenergic Pathway
0.1 8.2 PID_NOTCH_PATHWAY Notch signaling pathway
0.1 5.4 ST_FAS_SIGNALING_PATHWAY Fas Signaling Pathway
0.1 3.4 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 0.7 ST_INTEGRIN_SIGNALING_PATHWAY Integrin Signaling Pathway
0.1 2.4 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 1.9 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 1.3 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.1 0.9 PID_VEGFR1_2_PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.1 3.8 PID_P73PATHWAY p73 transcription factor network
0.1 2.2 PID_AP1_PATHWAY AP-1 transcription factor network
0.1 1.4 PID_ARF6_PATHWAY Arf6 signaling events
0.1 0.6 ST_DIFFERENTIATION_PATHWAY_IN_PC12_CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.1 0.3 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 0.4 PID_PTP1B_PATHWAY Signaling events mediated by PTP1B
0.0 1.1 PID_ARF_3PATHWAY Arf1 pathway
0.0 0.3 PID_CERAMIDE_PATHWAY Ceramide signaling pathway
0.0 1.0 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events
0.0 0.6 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.9 PID_TGFBR_PATHWAY TGF-beta receptor signaling
0.0 0.3 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.0 0.7 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.4 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.3 PID_REELIN_PATHWAY Reelin signaling pathway
0.0 0.3 PID_KIT_PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.8 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.0 0.4 PID_MTOR_4PATHWAY mTOR signaling pathway
0.0 0.6 PID_HDAC_CLASSI_PATHWAY Signaling events mediated by HDAC Class I

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 2.3 REACTOME_SIGNALING_BY_NOTCH2 Genes involved in Signaling by NOTCH2
2.1 16.7 REACTOME_TRANSPORT_OF_ORGANIC_ANIONS Genes involved in Transport of organic anions
2.0 6.1 REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY Genes involved in Endosomal/Vacuolar pathway
1.2 8.7 REACTOME_SIGNALING_BY_NOTCH4 Genes involved in Signaling by NOTCH4
1.2 47.9 REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 Genes involved in Nuclear signaling by ERBB4
0.9 17.0 REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.8 1.6 REACTOME_PLATELET_AGGREGATION_PLUG_FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.8 8.0 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.8 20.5 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.7 11.7 REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.7 39.0 REACTOME_AMYLOIDS Genes involved in Amyloids
0.7 14.0 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.7 5.2 REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.7 3.9 REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.6 5.2 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.6 3.2 REACTOME_SIGNALING_BY_EGFR_IN_CANCER Genes involved in Signaling by EGFR in Cancer
0.6 9.2 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.5 9.9 REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING Genes involved in Growth hormone receptor signaling
0.5 14.4 REACTOME_ENOS_ACTIVATION_AND_REGULATION Genes involved in eNOS activation and regulation
0.5 6.2 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.5 7.4 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.5 9.6 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.4 4.2 REACTOME_MRNA_DECAY_BY_3_TO_5_EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.4 10.0 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.4 3.9 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.4 6.6 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.4 10.9 REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT Genes involved in ABC-family proteins mediated transport
0.4 19.3 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.3 3.7 REACTOME_FGFR2C_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.3 20.6 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.3 1.9 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.3 3.2 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.3 4.7 REACTOME_MTORC1_MEDIATED_SIGNALLING Genes involved in mTORC1-mediated signalling
0.3 11.7 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.3 5.8 REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.3 6.6 REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.3 0.8 REACTOME_LYSOSOME_VESICLE_BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.3 1.8 REACTOME_PLATELET_CALCIUM_HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.3 1.5 REACTOME_ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.2 2.9 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.2 3.6 REACTOME_ACTIVATION_OF_GENES_BY_ATF4 Genes involved in Activation of Genes by ATF4
0.2 2.2 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.2 1.7 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.2 5.3 REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.2 1.9 REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.2 11.1 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.2 3.7 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.2 2.4 REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.2 2.5 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.2 10.8 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.2 1.8 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 1.6 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.1 1.6 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 1.4 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 2.0 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.1 3.0 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 7.8 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 1.2 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 6.5 REACTOME_DESTABILIZATION_OF_MRNA_BY_AUF1_HNRNP_D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.1 2.4 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.1 5.1 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 4.3 REACTOME_RNA_POL_III_TRANSCRIPTION Genes involved in RNA Polymerase III Transcription
0.1 2.2 REACTOME_RAS_ACTIVATION_UOPN_CA2_INFUX_THROUGH_NMDA_RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.1 3.0 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 1.7 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.1 4.9 REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.1 1.0 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 1.0 REACTOME_PURINE_CATABOLISM Genes involved in Purine catabolism
0.1 1.1 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 1.4 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 2.0 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 4.0 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.1 0.9 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.1 2.8 REACTOME_INHIBITION_OF_INSULIN_SECRETION_BY_ADRENALINE_NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1 2.8 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 1.2 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 3.7 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 1.0 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 0.9 REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.1 0.4 REACTOME_NFKB_ACTIVATION_THROUGH_FADD_RIP1_PATHWAY_MEDIATED_BY_CASPASE_8_AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.1 4.8 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 1.4 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 1.2 REACTOME_KERATAN_SULFATE_BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.1 3.7 REACTOME_3_UTR_MEDIATED_TRANSLATIONAL_REGULATION Genes involved in 3' -UTR-mediated translational regulation
0.1 1.2 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.0 1.0 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 1.4 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 1.6 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.7 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.0 0.3 REACTOME_SIGNALING_BY_PDGF Genes involved in Signaling by PDGF
0.0 0.7 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.4 REACTOME_BASIGIN_INTERACTIONS Genes involved in Basigin interactions
0.0 0.5 REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.8 REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.8 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.9 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.0 0.4 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.6 REACTOME_FORMATION_OF_TRANSCRIPTION_COUPLED_NER_TC_NER_REPAIR_COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0 0.5 REACTOME_IL1_SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.2 REACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.1 REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT Genes involved in Regulation of beta-cell development