---

Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr16_-_22439570	33.953	ENSMUST00000170393.1	Etv5	ets variant gene 5
chrX_-_51681703	26.948	ENSMUST00000088172.5	Hs6st2	heparan sulfate 6-O-sulfotransferase 2
chrX_-_51681856	26.798	ENSMUST00000114871.1	Hs6st2	heparan sulfate 6-O-sulfotransferase 2
chr13_+_76579670	23.356	ENSMUST00000126960.1 ENSMUST00000109583.2	Mctp1	multiple C2 domains, transmembrane 1
chr14_+_65971049	21.189	ENSMUST00000128539.1	Clu	clusterin
chr14_+_65970804	20.768	ENSMUST00000138191.1	Clu	clusterin
chr12_+_74288735	18.630	ENSMUST00000095617.1	1700086L19Rik	RIKEN cDNA 1700086L19 gene
chr11_-_101785252	18.292	ENSMUST00000164750.1 ENSMUST00000107176.1 ENSMUST00000017868.6	Etv4	ets variant gene 4 (E1A enhancer binding protein, E1AF)
chr1_-_91459254	18.114	ENSMUST00000069620.8	Per2	period circadian clock 2
chr14_+_65970610	17.659	ENSMUST00000127387.1	Clu	clusterin
chr9_-_40346290	17.059	ENSMUST00000121357.1	Gramd1b	GRAM domain containing 1B
chr5_+_117841839	16.577	ENSMUST00000142742.2	Nos1	nitric oxide synthase 1, neuronal
chr3_+_141465564	15.249	ENSMUST00000106236.2 ENSMUST00000075282.3	Unc5c	unc-5 homolog C (C. elegans)
chr13_+_16011851	15.120	ENSMUST00000042603.6	Inhba	inhibin beta-A
chr15_-_8710734	14.361	ENSMUST00000005493.7	Slc1a3	solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr9_-_21037775	14.280	ENSMUST00000180870.1	Gm26592	predicted gene, 26592
chr7_-_103827922	13.882	ENSMUST00000023934.6 ENSMUST00000153218.1	Hbb-bs	hemoglobin, beta adult s chain
chr2_-_25469742	13.579	ENSMUST00000114259.2 ENSMUST00000015234.6	Ptgds	prostaglandin D2 synthase (brain)
chr14_+_65971164	13.445	ENSMUST00000144619.1	Clu	clusterin
chr2_-_25470031	12.700	ENSMUST00000114251.1	Ptgds	prostaglandin D2 synthase (brain)
chr15_-_8710409	12.016	ENSMUST00000157065.1	Slc1a3	solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr18_+_23803962	11.967	ENSMUST00000025127.3	Mapre2	microtubule-associated protein, RP/EB family, member 2
chr16_-_76373827	11.841	ENSMUST00000121927.1	Nrip1	nuclear receptor interacting protein 1
chr17_+_69156791	11.747	ENSMUST00000112680.1 ENSMUST00000080208.5	Epb4.1l3	erythrocyte protein band 4.1-like 3
chrX_-_162565514	11.543	ENSMUST00000154424.1	Reps2	RALBP1 associated Eps domain containing protein 2
chr3_+_84952146	11.399	ENSMUST00000029727.7	Fbxw7	F-box and WD-40 domain protein 7
chr4_+_85205417	11.399	ENSMUST00000030212.8 ENSMUST00000107189.1 ENSMUST00000107184.1	Sh3gl2	SH3-domain GRB2-like 2
chr5_+_66968961	11.327	ENSMUST00000132991.1	Limch1	LIM and calponin homology domains 1
chr10_-_125308809	11.154	ENSMUST00000105257.2	Slc16a7	solute carrier family 16 (monocarboxylic acid transporters), member 7
chr14_+_48120841	11.037	ENSMUST00000073150.4	Peli2	pellino 2
chr7_+_92062392	11.019	ENSMUST00000098308.2	Dlg2	discs, large homolog 2 (Drosophila)
chr6_-_99044414	10.834	ENSMUST00000177507.1 ENSMUST00000123992.1	Foxp1	forkhead box P1
chr7_+_144175513	10.653	ENSMUST00000105900.1	Shank2	SH3/ankyrin domain gene 2
chr4_+_47208005	10.254	ENSMUST00000082303.6 ENSMUST00000102917.4	Col15a1	collagen, type XV, alpha 1
chr7_-_110862944	10.185	ENSMUST00000033050.3	Lyve1	lymphatic vessel endothelial hyaluronan receptor 1
chr2_+_131909928	10.092	ENSMUST00000091288.6	Prnp	prion protein
chr6_-_55681257	10.077	ENSMUST00000044767.8	Neurod6	neurogenic differentiation 6
chr3_+_51559973	9.920	ENSMUST00000180404.1	5031434O11Rik	RIKEN cDNA 5031434O11 gene
chr3_-_113574758	9.230	ENSMUST00000106540.1	Amy1	amylase 1, salivary
chr13_-_41079628	8.422	ENSMUST00000165087.1 ENSMUST00000070193.6	Mak	male germ cell-associated kinase
chr2_+_131909951	8.358	ENSMUST00000124100.1 ENSMUST00000136783.1	PRND	prion protein gene complex (Prn), transcript variant 1, mRNA
chr15_-_33687840	8.112	ENSMUST00000042021.3	Tspyl5	testis-specific protein, Y-encoded-like 5
chr2_-_131042682	8.090	ENSMUST00000028787.5 ENSMUST00000110239.1 ENSMUST00000110234.1	Gfra4	glial cell line derived neurotrophic factor family receptor alpha 4
chr8_-_60954726	7.808	ENSMUST00000110302.1	Clcn3	chloride channel 3
chr6_+_17463749	7.671	ENSMUST00000115443.1	Met	met proto-oncogene
chr18_+_37320374	7.604	ENSMUST00000078271.2	Pcdhb5	protocadherin beta 5
chr13_+_42866247	7.569	ENSMUST00000131942.1	Phactr1	phosphatase and actin regulator 1
chr11_-_106216318	7.520	ENSMUST00000002043.3	Ccdc47	coiled-coil domain containing 47
chr4_+_85205120	7.385	ENSMUST00000107188.3	Sh3gl2	SH3-domain GRB2-like 2
chr16_+_45093611	7.192	ENSMUST00000099498.2	Ccdc80	coiled-coil domain containing 80
chr15_-_37007382	7.031	ENSMUST00000078976.7	Zfp706	zinc finger protein 706
chr19_+_23141183	7.026	ENSMUST00000036884.1	Klf9	Kruppel-like factor 9
chr14_-_18239053	7.011	ENSMUST00000090543.5	Nr1d2	nuclear receptor subfamily 1, group D, member 2
chr6_-_99028874	6.980	ENSMUST00000154163.2	Foxp1	forkhead box P1
chr9_+_109931774	6.806	ENSMUST00000169851.2	Map4	microtubule-associated protein 4
chr4_+_101507855	6.789	ENSMUST00000038207.5	Dnajc6	DnaJ (Hsp40) homolog, subfamily C, member 6
chr1_-_140183404	6.649	ENSMUST00000066859.6 ENSMUST00000111976.2	Cfh	complement component factor h
chr18_-_36726730	6.608	ENSMUST00000061829.6	Cd14	CD14 antigen
chr1_-_58586191	6.355	ENSMUST00000038372.7 ENSMUST00000097724.3 ENSMUST00000161000.1 ENSMUST00000161600.1	Fam126b	family with sequence similarity 126, member B
chrX_-_103483205	6.304	ENSMUST00000127786.2	Xist	inactive X specific transcripts
chr3_+_51559757	6.267	ENSMUST00000180616.1	5031434O11Rik	RIKEN cDNA 5031434O11 gene
chr15_+_38933142	6.225	ENSMUST00000163313.1	Baalc	brain and acute leukemia, cytoplasmic
chr4_-_119538769	6.106	ENSMUST00000079611.6	AA415398	expressed sequence AA415398
chr4_+_101419696	6.101	ENSMUST00000131397.1 ENSMUST00000133055.1	Ak4	adenylate kinase 4
chr4_+_101507947	5.959	ENSMUST00000149047.1 ENSMUST00000106929.3	Dnajc6	DnaJ (Hsp40) homolog, subfamily C, member 6
chr12_+_85599047	5.812	ENSMUST00000177587.1	Jdp2	Jun dimerization protein 2
chr10_-_126901315	5.762	ENSMUST00000026504.5 ENSMUST00000168520.1	Xrcc6bp1	XRCC6 binding protein 1
chr17_-_45592569	5.734	ENSMUST00000163492.1	Slc29a1	solute carrier family 29 (nucleoside transporters), member 1
chr10_-_78464969	5.677	ENSMUST00000041616.8	Pdxk	pyridoxal (pyridoxine, vitamin B6) kinase
chr10_-_78464853	5.038	ENSMUST00000105385.1	Pdxk	pyridoxal (pyridoxine, vitamin B6) kinase
chr8_+_46490968	5.009	ENSMUST00000110372.1 ENSMUST00000130563.1	Acsl1	acyl-CoA synthetase long-chain family member 1
chr7_+_19004047	4.996	ENSMUST00000053713.3	Irf2bp1	interferon regulatory factor 2 binding protein 1
chr10_-_64090241	4.809	ENSMUST00000133588.1	Lrrtm3	leucine rich repeat transmembrane neuronal 3
chr4_-_121017201	4.803	ENSMUST00000043200.7	Smap2	small ArfGAP 2
chr7_-_29125142	4.796	ENSMUST00000179893.1 ENSMUST00000032813.9	Ryr1	ryanodine receptor 1, skeletal muscle
chr10_-_77418230	4.735	ENSMUST00000020496.7 ENSMUST00000098374.2 ENSMUST00000105406.1	Adarb1	adenosine deaminase, RNA-specific, B1
chr17_-_24073479	4.723	ENSMUST00000017090.5	Kctd5	potassium channel tetramerisation domain containing 5
chr17_-_45592485	4.715	ENSMUST00000166119.1	Slc29a1	solute carrier family 29 (nucleoside transporters), member 1
chr1_-_134955908	4.658	ENSMUST00000045665.6 ENSMUST00000086444.4 ENSMUST00000112163.1	Ppp1r12b	protein phosphatase 1, regulatory (inhibitor) subunit 12B
chr12_+_85599388	4.621	ENSMUST00000050687.6	Jdp2	Jun dimerization protein 2
chr9_+_40269273	4.464	ENSMUST00000176185.1	Scn3b	sodium channel, voltage-gated, type III, beta
chr1_-_140183283	4.341	ENSMUST00000111977.1	Cfh	complement component factor h
chr14_-_18893376	4.324	ENSMUST00000151926.1	Ube2e2	ubiquitin-conjugating enzyme E2E 2
chr9_+_109931458	4.299	ENSMUST00000072772.5 ENSMUST00000035055.8	Map4	microtubule-associated protein 4
chr3_-_146770218	4.168	ENSMUST00000106137.1	Prkacb	protein kinase, cAMP dependent, catalytic, beta
chr5_+_135009152	4.093	ENSMUST00000111216.1 ENSMUST00000046999.8	Abhd11	abhydrolase domain containing 11
chr19_-_8723356	4.087	ENSMUST00000170157.1	Slc3a2	solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
chr9_+_40269202	4.056	ENSMUST00000114956.3 ENSMUST00000049941.5	Scn3b	sodium channel, voltage-gated, type III, beta
chr3_-_146770603	3.763	ENSMUST00000106138.1	Prkacb	protein kinase, cAMP dependent, catalytic, beta
chr4_+_41941572	3.734	ENSMUST00000108028.2 ENSMUST00000153997.1	Gm20878	predicted gene, 20878
chr11_-_79530569	3.690	ENSMUST00000103236.3 ENSMUST00000170799.1 ENSMUST00000170422.2	Evi2a Evi2b	ecotropic viral integration site 2a ecotropic viral integration site 2b
chr16_+_3884629	3.666	ENSMUST00000176233.1	Gm20695	predicted gene 20695
chr9_+_21936986	3.553	ENSMUST00000046371.6	BC018242	cDNA sequence BC018242
chr15_-_38519227	3.447	ENSMUST00000110328.1 ENSMUST00000110329.1 ENSMUST00000065308.5	Azin1	antizyme inhibitor 1
chr2_-_132111440	3.319	ENSMUST00000128899.1	Slc23a2	solute carrier family 23 (nucleobase transporters), member 2
chr4_+_41942037	3.311	ENSMUST00000181518.1	Gm20878	predicted gene, 20878
chr9_+_109931863	3.265	ENSMUST00000165876.1	Map4	microtubule-associated protein 4
chr13_+_49504774	3.253	ENSMUST00000051504.7	Ecm2	extracellular matrix protein 2, female organ and adipocyte specific
chr16_+_92292380	3.167	ENSMUST00000047383.3	Kcne2	potassium voltage-gated channel, Isk-related subfamily, gene 2
chr17_-_80290476	3.147	ENSMUST00000086555.3 ENSMUST00000038166.7	Dhx57	DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
chr14_+_75136326	3.128	ENSMUST00000145303.1	Lcp1	lymphocyte cytosolic protein 1
chr10_-_31445921	3.127	ENSMUST00000000305.5	Tpd52l1	tumor protein D52-like 1
chr15_+_7129557	3.117	ENSMUST00000067190.5 ENSMUST00000164529.1	Lifr	leukemia inhibitory factor receptor
chr13_-_67451585	3.086	ENSMUST00000057241.8 ENSMUST00000075255.5	Zfp874a	zinc finger protein 874a
chr9_+_94669876	3.067	ENSMUST00000033463.9	Slc9a9	solute carrier family 9 (sodium/hydrogen exchanger), member 9
chr4_-_150003130	3.003	ENSMUST00000084117.6	H6pd	hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chr10_+_67185730	2.957	ENSMUST00000173689.1	Jmjd1c	jumonji domain containing 1C
chr1_-_38129618	2.917	ENSMUST00000027251.6	Rev1	REV1 homolog (S. cerevisiae)
chr2_-_60284292	2.905	ENSMUST00000028356.8 ENSMUST00000074606.4	Cd302	CD302 antigen
chr4_-_134853294	2.900	ENSMUST00000030628.8	Tmem57	transmembrane protein 57
chr7_+_96211656	2.854	ENSMUST00000107165.1	Tenm4	teneurin transmembrane protein 4
chr16_+_78930940	2.787	ENSMUST00000114216.1 ENSMUST00000069148.6 ENSMUST00000023568.7	Chodl	chondrolectin
chr2_-_114201416	2.730	ENSMUST00000050668.3	Zfp770	zinc finger protein 770
chr13_-_52981027	2.719	ENSMUST00000071065.7	Nfil3	nuclear factor, interleukin 3, regulated
chr10_-_64090265	2.599	ENSMUST00000105439.1	Lrrtm3	leucine rich repeat transmembrane neuronal 3
chr8_+_22060712	2.591	ENSMUST00000072572.6 ENSMUST00000110737.2 ENSMUST00000131624.1	Alg11	asparagine-linked glycosylation 11 (alpha-1,2-mannosyltransferase)
chr1_-_9299238	2.536	ENSMUST00000140295.1	Sntg1	syntrophin, gamma 1
chr4_-_41774097	2.466	ENSMUST00000108036.1 ENSMUST00000173865.1 ENSMUST00000108037.2 ENSMUST00000108032.2	Ccl27a	chemokine (C-C motif) ligand 27A
chr10_+_90071095	2.423	ENSMUST00000183109.1	Anks1b	ankyrin repeat and sterile alpha motif domain containing 1B
chr3_+_30792876	2.405	ENSMUST00000029256.7	Sec62	SEC62 homolog (S. cerevisiae)
chr8_-_109251698	2.385	ENSMUST00000079189.3	4922502B01Rik	RIKEN cDNA 4922502B01 gene
chr17_+_8283762	2.377	ENSMUST00000155364.1 ENSMUST00000046754.8 ENSMUST00000124023.1	Mpc1	mitochondrial pyruvate carrier 1
chr14_-_45388772	2.354	ENSMUST00000046191.7	Gnpnat1	glucosamine-phosphate N-acetyltransferase 1
chr9_-_78443204	2.328	ENSMUST00000070742.7 ENSMUST00000034898.7	Mb21d1	Mab-21 domain containing 1
chr3_+_88965812	2.317	ENSMUST00000090933.4	Ash1l	ash1 (absent, small, or homeotic)-like (Drosophila)
chr4_+_43493345	2.309	ENSMUST00000030181.5 ENSMUST00000107922.2	Ccdc107	coiled-coil domain containing 107
chr13_+_63014934	2.305	ENSMUST00000091560.4	2010111I01Rik	RIKEN cDNA 2010111I01 gene
chr4_+_101419277	2.263	ENSMUST00000102780.1 ENSMUST00000106946.1 ENSMUST00000106945.1	Ak4	adenylate kinase 4
chr14_-_55635602	2.232	ENSMUST00000047131.9	Ipo4	importin 4
chr9_-_110624361	2.150	ENSMUST00000035069.9	Nradd	neurotrophin receptor associated death domain
chr18_+_37742088	2.134	ENSMUST00000003599.6	Pcdhga9	protocadherin gamma subfamily A, 9
chr2_-_129371131	2.129	ENSMUST00000028881.7	Il1b	interleukin 1 beta
chr3_+_96181151	2.107	ENSMUST00000035371.8	Sv2a	synaptic vesicle glycoprotein 2 a
chr7_+_27447978	2.082	ENSMUST00000037399.9 ENSMUST00000108358.1	Blvrb	biliverdin reductase B (flavin reductase (NADPH))
chr7_+_28825202	2.040	ENSMUST00000066264.6	Ech1	enoyl coenzyme A hydratase 1, peroxisomal
chr12_-_87200200	2.031	ENSMUST00000037418.5	Tmed8	transmembrane emp24 domain containing 8
chr1_+_171840607	1.996	ENSMUST00000136479.1 ENSMUST00000042302.6	Cd84	CD84 antigen
chr16_-_15594472	1.980	ENSMUST00000118236.1 ENSMUST00000096234.3	Ube2v2	ubiquitin-conjugating enzyme E2 variant 2
chr9_+_110344185	1.967	ENSMUST00000142100.1	Scap	SREBF chaperone
chr5_+_24364804	1.952	ENSMUST00000030834.4 ENSMUST00000115090.1	Nos3	nitric oxide synthase 3, endothelial cell
chr6_+_121183667	1.941	ENSMUST00000118234.1 ENSMUST00000088561.3 ENSMUST00000137432.1 ENSMUST00000120066.1	Pex26	peroxisomal biogenesis factor 26
chr7_+_100607410	1.937	ENSMUST00000107048.1 ENSMUST00000032946.3	Rab6a	RAB6A, member RAS oncogene family
chr14_-_103099499	1.874	ENSMUST00000022720.8	Fbxl3	F-box and leucine-rich repeat protein 3
chr8_-_91134027	1.867	ENSMUST00000125257.1	Aktip	thymoma viral proto-oncogene 1 interacting protein
chr1_-_38898084	1.807	ENSMUST00000027249.6	Chst10	carbohydrate sulfotransferase 10
chr7_+_29238434	1.779	ENSMUST00000108237.1	Yif1b	Yip1 interacting factor homolog B (S. cerevisiae)
chr19_-_59943000	1.743	ENSMUST00000170819.1	Rab11fip2	RAB11 family interacting protein 2 (class I)
chr13_-_96471160	1.719	ENSMUST00000055607.5 ENSMUST00000181613.2	Ankdd1b	ankyrin repeat and death domain containing 1B
chr2_-_66410064	1.713	ENSMUST00000112366.1	Scn1a	sodium channel, voltage-gated, type I, alpha
chr16_-_89818338	1.645	ENSMUST00000164263.2	Tiam1	T cell lymphoma invasion and metastasis 1
chr1_+_21218575	1.640	ENSMUST00000027065.5 ENSMUST00000027064.7	Tmem14a	transmembrane protein 14A
chr2_+_129065934	1.632	ENSMUST00000035812.7	Ttl	tubulin tyrosine ligase
chr5_-_36695969	1.631	ENSMUST00000031091.9 ENSMUST00000140063.1	D5Ertd579e	DNA segment, Chr 5, ERATO Doi 579, expressed
chr13_-_25270076	1.602	ENSMUST00000057866.6	Nrsn1	neurensin 1
chr9_-_53248106	1.580	ENSMUST00000065630.6	Ddx10	DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
chr10_+_77978524	1.558	ENSMUST00000105397.3 ENSMUST00000105398.1	1810043G02Rik	RIKEN cDNA 1810043G02 gene
chr10_+_62980233	1.554	ENSMUST00000131718.1 ENSMUST00000119567.1 ENSMUST00000122231.1	Rufy2	RUN and FYVE domain-containing 2
chr4_+_152039315	1.545	ENSMUST00000084116.6 ENSMUST00000105663.1 ENSMUST00000103197.3	Nol9	nucleolar protein 9
chr11_-_71004387	1.508	ENSMUST00000124464.1 ENSMUST00000108527.1	Dhx33	DEAH (Asp-Glu-Ala-His) box polypeptide 33
chr3_+_138443085	1.495	ENSMUST00000005964.2	Adh5	alcohol dehydrogenase 5 (class III), chi polypeptide
chr5_-_122988533	1.458	ENSMUST00000086200.4 ENSMUST00000156474.1	Kdm2b	lysine (K)-specific demethylase 2B
chr4_-_133277730	1.457	ENSMUST00000105907.2	Tmem222	transmembrane protein 222
chr17_+_26715644	1.435	ENSMUST00000062519.7 ENSMUST00000144221.1 ENSMUST00000142539.1 ENSMUST00000151681.1	Crebrf	CREB3 regulatory factor
chr4_+_19575139	1.427	ENSMUST00000108253.1 ENSMUST00000029888.3	Rmdn1	regulator of microtubule dynamics 1
chr11_-_116086929	1.415	ENSMUST00000074628.6 ENSMUST00000106444.3	Wbp2	WW domain binding protein 2
chr7_-_14562171	1.402	ENSMUST00000181796.1	Vmn1r90	vomeronasal 1 receptor 90
chr1_-_161034794	1.333	ENSMUST00000177003.1 ENSMUST00000162226.2 ENSMUST00000159250.2	Zbtb37	zinc finger and BTB domain containing 37
chr3_-_30793549	1.308	ENSMUST00000180833.1	4933429H19Rik	RIKEN cDNA 4933429H19 gene
chr2_-_79908428	1.260	ENSMUST00000102652.3 ENSMUST00000102651.3	Pde1a	phosphodiesterase 1A, calmodulin-dependent
chr10_-_78185102	1.246	ENSMUST00000042556.9	Pwp2	PWP2 periodic tryptophan protein homolog (yeast)
chr16_-_15594507	1.231	ENSMUST00000115776.1 ENSMUST00000115777.3	Ube2v2	ubiquitin-conjugating enzyme E2 variant 2
chr4_-_42084291	1.203	ENSMUST00000177937.1	Gm21968	predicted gene, 21968
chr2_-_177324307	1.193	ENSMUST00000108959.2	Gm14412	predicted gene 14412
chr3_+_90341654	1.181	ENSMUST00000049382.4	Gatad2b	GATA zinc finger domain containing 2B
chrX_-_74428871	1.113	ENSMUST00000143521.1	G6pdx	glucose-6-phosphate dehydrogenase X-linked
chr7_-_127393604	1.103	ENSMUST00000165495.1 ENSMUST00000106303.2 ENSMUST00000074249.6	E430018J23Rik	RIKEN cDNA E430018J23 gene
chr7_+_29238323	1.077	ENSMUST00000108238.1 ENSMUST00000032809.3 ENSMUST00000138128.1	Yif1b	Yip1 interacting factor homolog B (S. cerevisiae)
chr11_+_106216926	1.032	ENSMUST00000021046.5	Ddx42	DEAD (Asp-Glu-Ala-Asp) box polypeptide 42
chr11_-_6200411	1.022	ENSMUST00000066496.3	Nudcd3	NudC domain containing 3
chr6_-_87809757	1.013	ENSMUST00000032134.7	Rab43	RAB43, member RAS oncogene family
chr2_-_37647199	0.992	ENSMUST00000028279.3	Strbp	spermatid perinuclear RNA binding protein
chr6_+_72347301	0.974	ENSMUST00000077783.3	0610030E20Rik	RIKEN cDNA 0610030E20 gene
chrX_+_163911401	0.969	ENSMUST00000140845.1	Ap1s2	adaptor-related protein complex 1, sigma 2 subunit
chr15_-_38078842	0.953	ENSMUST00000110336.2	Ubr5	ubiquitin protein ligase E3 component n-recognin 5
chr5_+_66676098	0.932	ENSMUST00000031131.9	Uchl1	ubiquitin carboxy-terminal hydrolase L1
chr13_-_21479441	0.929	ENSMUST00000076238.3	Gm10065	predicted gene 10065
chr15_+_68928414	0.870	ENSMUST00000022954.6	Khdrbs3	KH domain containing, RNA binding, signal transduction associated 3
chr17_-_21908092	0.849	ENSMUST00000106026.2	2210404O09Rik	RIKEN cDNA 2210404O09 gene
chr8_-_91133942	0.806	ENSMUST00000120213.1 ENSMUST00000109609.2	Aktip	thymoma viral proto-oncogene 1 interacting protein
chr18_+_32837225	0.785	ENSMUST00000166214.1 ENSMUST00000053663.9	Wdr36	WD repeat domain 36
chr3_+_88579602	0.732	ENSMUST00000035785.7	Ssr2	signal sequence receptor, beta
chr7_-_121074501	0.693	ENSMUST00000047194.2	Igsf6	immunoglobulin superfamily, member 6
chr3_-_94436574	0.667	ENSMUST00000029787.4	Oaz3	ornithine decarboxylase antizyme 3
chrX_-_94212638	0.651	ENSMUST00000113922.1	Eif2s3x	eukaryotic translation initiation factor 2, subunit 3, structural gene X-linked
chr10_+_11149406	0.646	ENSMUST00000044053.6	Shprh	SNF2 histone linker PHD RING helicase
chr6_+_42286709	0.622	ENSMUST00000163936.1	Clcn1	chloride channel 1
chr6_+_42286676	0.610	ENSMUST00000031894.6	Clcn1	chloride channel 1
chr2_-_168206875	0.598	ENSMUST00000057793.4	Adnp	activity-dependent neuroprotective protein
chr17_+_78508063	0.560	ENSMUST00000024880.9	Vit	vitrin
chr10_+_81176631	0.552	ENSMUST00000047864.9	Eef2	eukaryotic translation elongation factor 2

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
12.2	73.1	GO:1902998	macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
9.0	53.7	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
7.5	52.2	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
6.6	26.4	GO:0043490	malate-aspartate shuttle(GO:0043490)
6.0	18.1	GO:0031554	regulation of DNA-templated transcription, termination(GO:0031554)
5.5	16.6	GO:0099548	drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738) retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by nitric oxide(GO:0099548)
5.3	26.3	GO:2000255	negative regulation of male germ cell proliferation(GO:2000255)
3.9	11.8	GO:0001543	ovarian follicle rupture(GO:0001543)
3.6	10.7	GO:0042823	pyridoxal phosphate biosynthetic process(GO:0042823)
3.4	13.5	GO:1901475	pyruvate transmembrane transport(GO:1901475)
3.4	10.1	GO:1902938	regulation of intracellular calcium activated chloride channel activity(GO:1902938)
3.3	22.8	GO:1902856	negative regulation of nonmotile primary cilium assembly(GO:1902856)
3.0	15.1	GO:0042636	negative regulation of hair cycle(GO:0042636) progesterone secretion(GO:0042701) negative regulation of hair follicle development(GO:0051799) positive regulation of ovulation(GO:0060279)
2.7	18.8	GO:1990416	cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
2.6	7.8	GO:0097401	synaptic vesicle lumen acidification(GO:0097401)
2.3	11.4	GO:1903378	positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
2.1	12.7	GO:0072318	clathrin coat disassembly(GO:0072318)
2.1	6.3	GO:0060708	spongiotrophoblast differentiation(GO:0060708)
1.9	15.2	GO:0033564	anterior/posterior axon guidance(GO:0033564)
1.8	11.0	GO:0006957	complement activation, alternative pathway(GO:0006957)
1.8	17.8	GO:0061470	interleukin-21 production(GO:0032625) T follicular helper cell differentiation(GO:0061470) interleukin-21 secretion(GO:0072619)
1.7	6.6	GO:2000484	response to diacyl bacterial lipopeptide(GO:0071724) cellular response to diacyl bacterial lipopeptide(GO:0071726) positive regulation of interleukin-8 secretion(GO:2000484)
1.6	8.0	GO:0050847	progesterone receptor signaling pathway(GO:0050847)
1.6	4.7	GO:0061744	motor behavior(GO:0061744)
1.5	10.4	GO:0015862	uridine transport(GO:0015862)
1.4	7.0	GO:1902455	negative regulation of stem cell population maintenance(GO:1902455)
1.3	10.2	GO:0006027	glycosaminoglycan catabolic process(GO:0006027)
1.2	2.5	GO:0071677	positive regulation of mononuclear cell migration(GO:0071677)
1.1	3.4	GO:0009446	putrescine biosynthetic process(GO:0009446)
1.1	3.3	GO:0015882	L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
1.1	7.7	GO:0070494	regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
1.1	3.2	GO:0042275	error-free postreplication DNA repair(GO:0042275)
1.1	2.1	GO:0060558	regulation of calcidiol 1-monooxygenase activity(GO:0060558)
1.0	3.1	GO:0038165	oncostatin-M-mediated signaling pathway(GO:0038165)
1.0	2.0	GO:0031284	positive regulation of guanylate cyclase activity(GO:0031284)
1.0	4.8	GO:0071313	cellular response to caffeine(GO:0071313)
1.0	9.6	GO:0008063	Toll signaling pathway(GO:0008063)
0.9	8.5	GO:0060373	regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371) regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.8	7.4	GO:1902004	positive regulation of beta-amyloid formation(GO:1902004)
0.8	4.1	GO:0015803	branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.8	11.0	GO:0045161	neuronal ion channel clustering(GO:0045161)
0.8	7.5	GO:0006983	ER overload response(GO:0006983)
0.7	7.9	GO:1901621	negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.7	2.9	GO:0032289	central nervous system myelin formation(GO:0032289) cardiac cell fate specification(GO:0060912)
0.7	2.0	GO:2001180	regulation of interleukin-18 production(GO:0032661) negative regulation of interleukin-18 production(GO:0032701) negative regulation of interleukin-10 secretion(GO:2001180)
0.6	5.0	GO:0044539	long-chain fatty acid import(GO:0044539)
0.6	1.1	GO:0002034	angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001998) regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072)
0.5	1.6	GO:1900149	positive regulation of Schwann cell migration(GO:1900149)
0.5	4.3	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.5	3.2	GO:1901979	regulation of inward rectifier potassium channel activity(GO:1901979)
0.5	1.5	GO:0000448	cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
0.5	1.5	GO:0034310	primary alcohol catabolic process(GO:0034310)
0.5	2.9	GO:0042276	error-prone translesion synthesis(GO:0042276)
0.5	2.4	GO:0006620	posttranslational protein targeting to membrane(GO:0006620)
0.5	2.4	GO:0006048	glucosamine metabolic process(GO:0006041) UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.5	10.1	GO:0021542	dentate gyrus development(GO:0021542)
0.4	3.0	GO:0030718	germ-line stem cell population maintenance(GO:0030718)
0.4	3.2	GO:0019227	neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.4	10.4	GO:0031065	positive regulation of histone deacetylation(GO:0031065)
0.4	8.4	GO:0046033	AMP metabolic process(GO:0046033)
0.4	1.9	GO:0018125	peptidyl-cysteine methylation(GO:0018125)
0.4	10.7	GO:0071625	vocalization behavior(GO:0071625)
0.3	1.0	GO:0035526	retrograde transport, plasma membrane to Golgi(GO:0035526)
0.3	7.0	GO:2001014	regulation of skeletal muscle cell differentiation(GO:2001014)
0.3	2.3	GO:0002674	negative regulation of acute inflammatory response(GO:0002674)
0.3	3.1	GO:0097369	sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.3	1.5	GO:0021993	initiation of neural tube closure(GO:0021993)
0.3	1.4	GO:1900170	negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.3	2.1	GO:0042167	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.2	1.9	GO:0015919	peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.2	1.4	GO:0071442	positive regulation of histone H3-K14 acetylation(GO:0071442)
0.2	0.9	GO:0007412	axon target recognition(GO:0007412)
0.2	8.1	GO:0071480	cellular response to gamma radiation(GO:0071480)
0.2	3.0	GO:0006098	pentose-phosphate shunt(GO:0006098)
0.2	3.1	GO:0071803	actin filament network formation(GO:0051639) positive regulation of podosome assembly(GO:0071803)
0.2	2.2	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.2	2.4	GO:1900383	regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.2	2.3	GO:0071360	cellular response to exogenous dsRNA(GO:0071360)
0.2	0.7	GO:1902047	polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267)
0.2	2.1	GO:0014052	regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.1	1.8	GO:0006490	oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.1	0.5	GO:0070859	positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
0.1	0.4	GO:1902951	negative regulation of dendritic spine maintenance(GO:1902951)
0.1	2.0	GO:0032933	response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.1	2.7	GO:0071353	cellular response to interleukin-4(GO:0071353)
0.1	11.0	GO:0010811	positive regulation of cell-substrate adhesion(GO:0010811)
0.1	18.9	GO:0031032	actomyosin structure organization(GO:0031032)
0.1	0.6	GO:2000767	positive regulation of cytoplasmic translation(GO:2000767)
0.1	6.8	GO:0030279	negative regulation of ossification(GO:0030279)
0.1	1.3	GO:0034390	smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391)
0.1	1.9	GO:0043153	entrainment of circadian clock by photoperiod(GO:0043153)
0.1	9.2	GO:0016052	carbohydrate catabolic process(GO:0016052)
0.1	2.7	GO:0045022	early endosome to late endosome transport(GO:0045022)
0.1	0.2	GO:0060672	epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.1	1.2	GO:0000028	ribosomal small subunit assembly(GO:0000028)
0.1	1.8	GO:0007616	long-term memory(GO:0007616)
0.1	0.3	GO:0001575	globoside metabolic process(GO:0001575)
0.1	0.7	GO:0006613	cotranslational protein targeting to membrane(GO:0006613)
0.1	1.8	GO:0043171	peptide catabolic process(GO:0043171)
0.1	1.5	GO:0045943	positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.1	0.4	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0	1.0	GO:0007638	mechanosensory behavior(GO:0007638)
0.0	0.2	GO:0086023	adrenergic receptor signaling pathway involved in heart process(GO:0086023)
0.0	0.3	GO:0035095	behavioral response to nicotine(GO:0035095)
0.0	0.3	GO:0017196	N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0	1.8	GO:0010501	RNA secondary structure unwinding(GO:0010501)
0.0	4.6	GO:0007416	synapse assembly(GO:0007416)
0.0	1.7	GO:1903078	positive regulation of protein localization to plasma membrane(GO:1903078)
0.0	2.9	GO:0006888	ER to Golgi vesicle-mediated transport(GO:0006888)
0.0	0.3	GO:0032464	positive regulation of protein homooligomerization(GO:0032464)
0.0	0.1	GO:1990927	negative regulation of tumor necrosis factor secretion(GO:1904468) negative regulation of membrane invagination(GO:1905154) calcium ion regulated lysosome exocytosis(GO:1990927)
0.0	1.0	GO:0008542	visual learning(GO:0008542)
0.0	2.9	GO:0006909	phagocytosis(GO:0006909)
0.0	0.8	GO:0001895	retina homeostasis(GO:0001895)
0.0	0.1	GO:0032782	bile acid secretion(GO:0032782) response to mercury ion(GO:0046689)
0.0	0.9	GO:0033120	positive regulation of RNA splicing(GO:0033120)
0.0	0.3	GO:0034389	lipid particle organization(GO:0034389)
0.0	2.6	GO:2001235	positive regulation of apoptotic signaling pathway(GO:2001235)
0.0	0.5	GO:0000038	very long-chain fatty acid metabolic process(GO:0000038)
0.0	0.3	GO:0030835	negative regulation of actin filament depolymerization(GO:0030835)
0.0	0.0	GO:0035590	purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0	0.1	GO:0032402	establishment of melanosome localization(GO:0032401) melanosome transport(GO:0032402) pigment granule transport(GO:0051904) establishment of pigment granule localization(GO:0051905)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
10.4	73.1	GO:0034366	spherical high-density lipoprotein particle(GO:0034366)
5.0	15.1	GO:0043512	inhibin A complex(GO:0043512)
3.5	13.9	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
2.8	11.4	GO:1990452	Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
1.5	16.6	GO:0042582	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
1.2	4.8	GO:0014802	terminal cisterna(GO:0014802)
1.2	10.7	GO:0005883	neurofilament(GO:0005883)
1.1	6.6	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
1.1	3.2	GO:0031372	UBC13-MMS2 complex(GO:0031372)
0.9	7.8	GO:0042581	specific granule(GO:0042581)
0.7	10.5	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
0.7	11.0	GO:0005614	interstitial matrix(GO:0005614)
0.6	8.4	GO:0097542	ciliary tip(GO:0097542)
0.6	1.9	GO:0070381	endosome to plasma membrane transport vesicle(GO:0070381)
0.6	6.3	GO:0000805	X chromosome(GO:0000805)
0.6	7.9	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.6	11.0	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.4	2.7	GO:0070695	FHF complex(GO:0070695)
0.3	12.7	GO:0060076	postsynaptic density(GO:0014069) excitatory synapse(GO:0060076) postsynaptic specialization(GO:0099572)
0.3	2.0	GO:0034388	Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.3	12.0	GO:0035371	microtubule plus-end(GO:0035371)
0.2	22.4	GO:0005791	rough endoplasmic reticulum(GO:0005791)
0.2	1.6	GO:0060091	kinocilium(GO:0060091)
0.2	2.2	GO:0005641	nuclear envelope lumen(GO:0005641)
0.2	46.1	GO:0016323	basolateral plasma membrane(GO:0016323)
0.2	11.7	GO:0072562	blood microparticle(GO:0072562)
0.2	3.7	GO:0030992	intraciliary transport particle B(GO:0030992)
0.2	14.4	GO:0005930	axoneme(GO:0005930)
0.2	18.2	GO:0031225	anchored component of membrane(GO:0031225)
0.1	10.3	GO:0005581	collagen trimer(GO:0005581)
0.1	3.2	GO:0001891	phagocytic cup(GO:0001891)
0.1	11.8	GO:0000118	histone deacetylase complex(GO:0000118)
0.1	4.7	GO:0031672	A band(GO:0031672)
0.1	1.5	GO:0031519	PcG protein complex(GO:0031519)
0.1	13.2	GO:0005769	early endosome(GO:0005769)
0.1	2.4	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1	0.7	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1	7.0	GO:0005778	peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1	2.1	GO:0030285	integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1	2.0	GO:0005901	caveola(GO:0005901)
0.1	2.9	GO:0030134	ER to Golgi transport vesicle(GO:0030134)
0.1	2.4	GO:0031305	integral component of mitochondrial inner membrane(GO:0031305)
0.1	1.6	GO:0032391	photoreceptor connecting cilium(GO:0032391)
0.1	1.2	GO:0044815	nucleosome(GO:0000786) DNA packaging complex(GO:0044815)
0.1	4.2	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1	7.6	GO:0045202	synapse(GO:0045202)
0.1	0.4	GO:0030015	CCR4-NOT core complex(GO:0030015)
0.0	0.3	GO:0005921	gap junction(GO:0005921)
0.0	1.0	GO:0045335	phagocytic vesicle(GO:0045335)
0.0	3.2	GO:0008076	voltage-gated potassium channel complex(GO:0008076)
0.0	1.0	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.0	0.5	GO:0030061	mitochondrial crista(GO:0030061)
0.0	2.1	GO:0043195	terminal bouton(GO:0043195)
0.0	2.3	GO:0005923	bicellular tight junction(GO:0005923)
0.0	1.9	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	1.2	GO:0034707	chloride channel complex(GO:0034707)
0.0	2.5	GO:0032587	ruffle membrane(GO:0032587)
0.0	13.2	GO:0048471	perinuclear region of cytoplasm(GO:0048471)
0.0	112.6	GO:0016021	integral component of membrane(GO:0016021)
0.0	0.1	GO:0030286	dynein complex(GO:0030286)
0.0	1.0	GO:0005905	clathrin-coated pit(GO:0005905)
0.0	0.9	GO:0044306	neuron projection terminus(GO:0044306)
0.0	1.5	GO:0045111	intermediate filament cytoskeleton(GO:0045111)
0.0	2.1	GO:0030141	secretory granule(GO:0030141)
0.0	0.6	GO:0016235	aggresome(GO:0016235)
0.0	14.0	GO:0005730	nucleolus(GO:0005730)
0.0	1.6	GO:0009898	cytoplasmic side of plasma membrane(GO:0009898)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
13.4	53.7	GO:0017095	heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
6.6	26.3	GO:0004667	prostaglandin-D synthase activity(GO:0004667)
6.2	18.5	GO:0004517	nitric-oxide synthase activity(GO:0004517)
3.6	10.7	GO:0031403	lithium ion binding(GO:0031403)
3.5	20.9	GO:0015501	glutamate:sodium symporter activity(GO:0015501)
3.5	13.9	GO:0031721	haptoglobin binding(GO:0031720) hemoglobin alpha binding(GO:0031721)
3.4	13.5	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
3.1	9.2	GO:0016160	alpha-amylase activity(GO:0004556) amylase activity(GO:0016160)
3.0	73.1	GO:0051787	misfolded protein binding(GO:0051787)
2.8	8.4	GO:0046899	nucleoside triphosphate adenylate kinase activity(GO:0046899)
2.7	11.0	GO:0001851	complement component C3b binding(GO:0001851)
2.7	8.1	GO:0016167	glial cell-derived neurotrophic factor receptor activity(GO:0016167)
2.5	15.2	GO:0005042	netrin receptor activity(GO:0005042)
2.5	10.1	GO:1903135	cupric ion binding(GO:1903135)
2.5	15.1	GO:0070699	type II activin receptor binding(GO:0070699)
2.3	11.4	GO:0050816	phosphothreonine binding(GO:0050816)
2.2	6.6	GO:0071723	lipopeptide binding(GO:0071723)
2.0	7.8	GO:0072320	volume-sensitive chloride channel activity(GO:0072320)
1.9	7.7	GO:0005008	hepatocyte growth factor-activated receptor activity(GO:0005008)
1.7	5.0	GO:0043758	acetate-CoA ligase (ADP-forming) activity(GO:0043758)
1.6	4.8	GO:0005219	ryanodine-sensitive calcium-release channel activity(GO:0005219)
1.2	8.5	GO:0086006	voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
1.2	4.7	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
1.2	7.0	GO:0004887	thyroid hormone receptor activity(GO:0004887)
1.1	18.1	GO:1990226	histone methyltransferase binding(GO:1990226)
1.1	3.3	GO:0070890	L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
1.1	3.3	GO:0070052	collagen V binding(GO:0070052)
1.0	3.1	GO:0004923	leukemia inhibitory factor receptor activity(GO:0004923) oncostatin-M receptor activity(GO:0004924)
1.0	4.1	GO:0004345	glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.9	2.6	GO:0000026	alpha-1,2-mannosyltransferase activity(GO:0000026)
0.8	4.1	GO:0042979	ornithine decarboxylase regulator activity(GO:0042979)
0.8	7.9	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.7	13.0	GO:0005540	hyaluronic acid binding(GO:0005540)
0.7	4.3	GO:0042296	ISG15 transferase activity(GO:0042296)
0.6	3.2	GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.5	2.1	GO:0004074	biliverdin reductase activity(GO:0004074)
0.5	1.5	GO:0004022	alcohol dehydrogenase (NAD) activity(GO:0004022)
0.5	11.0	GO:0004385	guanylate kinase activity(GO:0004385)
0.4	2.2	GO:0005166	neurotrophin p75 receptor binding(GO:0005166)
0.4	10.4	GO:0005337	nucleoside transmembrane transporter activity(GO:0005337)
0.4	11.8	GO:0046965	retinoid X receptor binding(GO:0046965)
0.4	2.3	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.4	3.1	GO:0015386	potassium:proton antiporter activity(GO:0015386)
0.3	10.7	GO:0035255	ionotropic glutamate receptor binding(GO:0035255)
0.3	7.2	GO:0001968	fibronectin binding(GO:0001968)
0.3	7.6	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.2	0.9	GO:0031694	alpha-2A adrenergic receptor binding(GO:0031694)
0.2	1.5	GO:0051731	polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.2	0.4	GO:0001226	RNA polymerase II transcription corepressor binding(GO:0001226)
0.2	2.1	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.2	4.7	GO:0097602	cullin family protein binding(GO:0097602)
0.2	1.3	GO:0048101	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.2	3.0	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1	1.5	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1	1.5	GO:0000182	rDNA binding(GO:0000182)
0.1	4.1	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.1	2.0	GO:0031402	sodium ion binding(GO:0031402)
0.1	1.0	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1	4.1	GO:0015175	neutral amino acid transmembrane transporter activity(GO:0015175)
0.1	4.1	GO:0046875	ephrin receptor binding(GO:0046875)
0.1	0.4	GO:0042610	CD8 receptor binding(GO:0042610)
0.1	1.2	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.1	1.9	GO:0031489	myosin V binding(GO:0031489)
0.1	36.4	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.1	3.2	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631)
0.1	1.8	GO:0070006	metalloaminopeptidase activity(GO:0070006)
0.1	9.9	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.1	13.6	GO:0017124	SH3 domain binding(GO:0017124)
0.1	2.2	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.1	4.9	GO:0004004	RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.1	6.4	GO:0004860	protein kinase inhibitor activity(GO:0004860)
0.1	1.6	GO:0016881	acid-amino acid ligase activity(GO:0016881)
0.1	29.2	GO:0005509	calcium ion binding(GO:0005509)
0.1	14.1	GO:0008017	microtubule binding(GO:0008017)
0.1	0.3	GO:0016018	cyclosporin A binding(GO:0016018)
0.0	1.2	GO:0030515	snoRNA binding(GO:0030515)
0.0	0.5	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0	2.2	GO:0015485	cholesterol binding(GO:0015485)
0.0	2.4	GO:0003684	damaged DNA binding(GO:0003684)
0.0	0.6	GO:0008097	5S rRNA binding(GO:0008097)
0.0	1.8	GO:0008146	sulfotransferase activity(GO:0008146)
0.0	0.1	GO:0015166	polyol transmembrane transporter activity(GO:0015166) glycerol transmembrane transporter activity(GO:0015168) glycerol channel activity(GO:0015254)
0.0	2.4	GO:0048029	monosaccharide binding(GO:0048029)
0.0	0.3	GO:0022848	acetylcholine-gated cation channel activity(GO:0022848)
0.0	0.2	GO:0042030	ATPase inhibitor activity(GO:0042030)
0.0	0.3	GO:0015643	toxic substance binding(GO:0015643)
0.0	7.7	GO:0061630	ubiquitin protein ligase activity(GO:0061630)
0.0	2.3	GO:0008565	protein transporter activity(GO:0008565)
0.0	14.1	GO:0008289	lipid binding(GO:0008289)
0.0	1.0	GO:0003725	double-stranded RNA binding(GO:0003725)
0.0	2.2	GO:0016779	nucleotidyltransferase activity(GO:0016779)
0.0	0.3	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596) H4 histone acetyltransferase activity(GO:0010485)
0.0	3.4	GO:0003713	transcription coactivator activity(GO:0003713)
0.0	0.0	GO:0031686	A1 adenosine receptor binding(GO:0031686)
0.0	2.0	GO:0016853	isomerase activity(GO:0016853)
0.0	1.5	GO:0030246	carbohydrate binding(GO:0030246)
0.0	1.2	GO:0051117	ATPase binding(GO:0051117)
0.0	1.7	GO:0017137	Rab GTPase binding(GO:0017137)
0.0	1.0	GO:0051082	unfolded protein binding(GO:0051082)
0.0	5.4	GO:0019901	protein kinase binding(GO:0019901)
0.0	3.5	GO:0050839	cell adhesion molecule binding(GO:0050839)
0.0	4.3	GO:0003682	chromatin binding(GO:0003682)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.1	34.0	PID_IL12_STAT4_PATHWAY	IL12 signaling mediated by STAT4
1.0	18.1	PID_CIRCADIAN_PATHWAY	Circadian rhythm pathway
0.9	73.1	PID_MYC_REPRESS_PATHWAY	Validated targets of C-MYC transcriptional repression
0.4	10.5	PID_GLYPICAN_1PATHWAY	Glypican 1 network
0.4	11.4	PID_MYC_PATHWAY	C-MYC pathway
0.4	15.1	PID_ALK1_PATHWAY	ALK1 signaling events
0.4	15.2	PID_NETRIN_PATHWAY	Netrin-mediated signaling events
0.4	17.9	PID_SYNDECAN_1_PATHWAY	Syndecan-1-mediated signaling events
0.4	14.5	PID_INTEGRIN_A4B1_PATHWAY	Alpha4 beta1 integrin signaling events
0.3	18.8	PID_RHOA_PATHWAY	RhoA signaling pathway
0.3	18.3	PID_LKB1_PATHWAY	LKB1 signaling events
0.3	11.8	PID_HNF3A_PATHWAY	FOXA1 transcription factor network
0.3	2.1	PID_ANTHRAX_PATHWAY	Cellular roles of Anthrax toxin
0.3	10.4	PID_ATF2_PATHWAY	ATF-2 transcription factor network
0.1	5.0	ST_MYOCYTE_AD_PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1	2.0	PID_VEGFR1_PATHWAY	VEGFR1 specific signals
0.1	1.6	PID_EPHA2_FWD_PATHWAY	EPHA2 forward signaling
0.1	8.4	PID_AR_PATHWAY	Coregulation of Androgen receptor activity
0.1	2.0	SA_CASPASE_CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1	2.8	PID_NFAT_TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	0.9	PID_ALPHA_SYNUCLEIN_PATHWAY	Alpha-synuclein signaling
0.0	3.8	NABA_ECM_GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	2.0	PID_P53_DOWNSTREAM_PATHWAY	Direct p53 effectors
0.0	1.2	PID_HDAC_CLASSI_PATHWAY	Signaling events mediated by HDAC Class I

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.8	15.1	REACTOME_GLYCOPROTEIN_HORMONES	Genes involved in Glycoprotein hormones
2.2	11.0	REACTOME_REGULATION_OF_COMPLEMENT_CASCADE	Genes involved in Regulation of Complement cascade
1.4	53.7	REACTOME_HS_GAG_BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
1.3	6.6	REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1	Genes involved in IKK complex recruitment mediated by RIP1
1.2	11.2	REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
1.0	10.2	REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.9	18.8	REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.8	73.4	REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_	Genes involved in Response to elevated platelet cytosolic Ca2+
0.7	9.6	REACTOME_IRAK1_RECRUITS_IKK_COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.7	18.5	REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.5	13.7	REACTOME_LYSOSOME_VESICLE_BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.4	25.0	REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.4	18.1	REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.4	18.2	REACTOME_NCAM1_INTERACTIONS	Genes involved in NCAM1 interactions
0.3	7.9	REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB	Genes involved in PKA-mediated phosphorylation of CREB
0.3	13.3	REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.3	15.7	REACTOME_NETRIN1_SIGNALING	Genes involved in Netrin-1 signaling
0.3	10.4	REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.2	5.0	REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.2	10.3	REACTOME_COLLAGEN_FORMATION	Genes involved in Collagen formation
0.2	8.5	REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.2	14.0	REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.2	7.7	REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING	Genes involved in Sema4D in semaphorin signaling
0.1	2.4	REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1	1.8	REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.1	0.6	REACTOME_PEPTIDE_CHAIN_ELONGATION	Genes involved in Peptide chain elongation
0.1	7.0	REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.1	1.3	REACTOME_CA_DEPENDENT_EVENTS	Genes involved in Ca-dependent events
0.1	1.9	REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.1	2.1	REACTOME_METABOLISM_OF_PORPHYRINS	Genes involved in Metabolism of porphyrins
0.1	3.1	REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.1	2.1	REACTOME_IL1_SIGNALING	Genes involved in Interleukin-1 signaling
0.1	4.1	REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE_ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.1	2.6	REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0	1.7	REACTOME_REGULATION_OF_WATER_BALANCE_BY_RENAL_AQUAPORINS	Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0	0.5	REACTOME_STEROID_HORMONES	Genes involved in Steroid hormones
0.0	0.1	REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	2.6	REACTOME_DNA_REPAIR	Genes involved in DNA Repair
0.0	5.1	REACTOME_MRNA_PROCESSING	Genes involved in mRNA Processing
0.0	0.4	REACTOME_DEADENYLATION_OF_MRNA	Genes involved in Deadenylation of mRNA

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