Motif ID: Nhlh1

Z-value: 1.113


Transcription factors associated with Nhlh1:

Gene SymbolEntrez IDGene Name
Nhlh1 ENSMUSG00000051251.3 Nhlh1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nhlh1mm10_v2_chr1_-_172057573_1720575980.216.4e-02Click!


Activity profile for motif Nhlh1.

activity profile for motif Nhlh1


Sorted Z-values histogram for motif Nhlh1

Sorted Z-values for motif Nhlh1



Network of associatons between targets according to the STRING database.



First level regulatory network of Nhlh1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_+_56887795 6.955 ENSMUST00000022511.8
Zmym2
zinc finger, MYM-type 2
chrX_+_35888808 6.846 ENSMUST00000033419.6
Dock11
dedicator of cytokinesis 11
chr6_-_56362356 6.577 ENSMUST00000044505.7
ENSMUST00000166102.1
ENSMUST00000164037.1
ENSMUST00000114327.2
Pde1c



phosphodiesterase 1C



chr13_-_111808938 6.212 ENSMUST00000109267.2
Map3k1
mitogen-activated protein kinase kinase kinase 1
chr7_-_28302238 6.208 ENSMUST00000108315.3
Dll3
delta-like 3 (Drosophila)
chr2_+_158375638 6.140 ENSMUST00000109488.1
Snhg11
small nucleolar RNA host gene 11
chr1_-_52500679 5.786 ENSMUST00000069792.7
Nab1
Ngfi-A binding protein 1
chr9_+_83834684 5.685 ENSMUST00000070326.7
Ttk
Ttk protein kinase
chr5_+_139543889 5.125 ENSMUST00000174792.1
ENSMUST00000031523.8
Uncx

UNC homeobox

chr2_+_102658640 4.740 ENSMUST00000080210.3
Slc1a2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr8_+_105518736 4.652 ENSMUST00000034363.5
Hsd11b2
hydroxysteroid 11-beta dehydrogenase 2
chr7_+_122289297 4.520 ENSMUST00000064989.5
ENSMUST00000064921.4
Prkcb

protein kinase C, beta

chr7_+_62376979 4.396 ENSMUST00000080403.5
Magel2
melanoma antigen, family L, 2
chr1_-_84696182 4.283 ENSMUST00000049126.6
Dner
delta/notch-like EGF-related receptor
chr14_+_34673888 4.023 ENSMUST00000048263.7
Wapal
wings apart-like homolog (Drosophila)
chr6_+_14901344 3.991 ENSMUST00000115477.1
Foxp2
forkhead box P2
chr4_+_95967205 3.948 ENSMUST00000030306.7
Hook1
hook homolog 1 (Drosophila)
chr8_+_45658273 3.942 ENSMUST00000153798.1
Sorbs2
sorbin and SH3 domain containing 2
chr4_+_45184815 3.901 ENSMUST00000134280.1
ENSMUST00000044773.5
Frmpd1

FERM and PDZ domain containing 1

chr9_-_57836706 3.849 ENSMUST00000164010.1
ENSMUST00000171444.1
ENSMUST00000098686.3
Arid3b


AT rich interactive domain 3B (BRIGHT-like)


chr4_-_34882919 3.826 ENSMUST00000098163.2
ENSMUST00000047950.5
Zfp292

zinc finger protein 292

chr2_-_60963192 3.814 ENSMUST00000028347.6
Rbms1
RNA binding motif, single stranded interacting protein 1
chr9_+_67840386 3.803 ENSMUST00000077879.5
Vps13c
vacuolar protein sorting 13C (yeast)
chr11_+_117849223 3.754 ENSMUST00000081387.4
Birc5
baculoviral IAP repeat-containing 5
chr19_+_25610533 3.751 ENSMUST00000048935.4
Dmrt3
doublesex and mab-3 related transcription factor 3
chr11_-_28583995 3.746 ENSMUST00000146385.2
Ccdc85a
coiled-coil domain containing 85A
chr8_+_45658666 3.695 ENSMUST00000134675.1
ENSMUST00000139869.1
ENSMUST00000126067.1
Sorbs2


sorbin and SH3 domain containing 2


chr13_+_24638636 3.671 ENSMUST00000110384.2
ENSMUST00000058009.9
ENSMUST00000038477.6
Fam65b


family with sequence similarity 65, member B


chr1_+_174501796 3.520 ENSMUST00000030039.7
Fmn2
formin 2
chr7_+_79660196 3.460 ENSMUST00000035977.7
Ticrr
TOPBP1-interacting checkpoint and replication regulator
chr2_+_119047116 3.441 ENSMUST00000152380.1
ENSMUST00000099542.2
Casc5

cancer susceptibility candidate 5

chr12_-_40038025 3.432 ENSMUST00000101472.3
Arl4a
ADP-ribosylation factor-like 4A
chr8_+_45658731 3.415 ENSMUST00000143820.1
ENSMUST00000132139.1
Sorbs2

sorbin and SH3 domain containing 2

chr12_-_40037387 3.406 ENSMUST00000146905.1
Arl4a
ADP-ribosylation factor-like 4A
chr1_+_129273344 3.385 ENSMUST00000073527.6
ENSMUST00000040311.7
Thsd7b

thrombospondin, type I, domain containing 7B

chr1_+_6730051 3.384 ENSMUST00000043578.6
ENSMUST00000131467.1
ENSMUST00000150761.1
ENSMUST00000151281.1
St18



suppression of tumorigenicity 18



chr6_+_104492790 3.355 ENSMUST00000161446.1
ENSMUST00000161070.1
ENSMUST00000089215.5
Cntn6


contactin 6


chrX_-_133688978 3.279 ENSMUST00000149154.1
ENSMUST00000167944.1
Pcdh19

protocadherin 19

chr6_+_47244359 3.258 ENSMUST00000060839.6
Cntnap2
contactin associated protein-like 2
chr14_+_34673948 3.235 ENSMUST00000090027.3
Wapal
wings apart-like homolog (Drosophila)
chr18_-_46198810 3.224 ENSMUST00000167364.1
Trim36
tripartite motif-containing 36
chr1_-_54557595 3.206 ENSMUST00000097739.3
Pgap1
post-GPI attachment to proteins 1
chr11_+_99864476 3.164 ENSMUST00000092694.3
Gm11559
predicted gene 11559
chr11_+_117849286 3.129 ENSMUST00000093906.4
Birc5
baculoviral IAP repeat-containing 5
chr2_-_181043540 3.092 ENSMUST00000124400.1
Chrna4
cholinergic receptor, nicotinic, alpha polypeptide 4
chr5_-_66618636 3.064 ENSMUST00000162382.1
ENSMUST00000160870.1
ENSMUST00000087256.5
ENSMUST00000160103.1
ENSMUST00000162349.1
Apbb2




amyloid beta (A4) precursor protein-binding, family B, member 2




chr4_-_63403330 3.062 ENSMUST00000035724.4
Akna
AT-hook transcription factor
chr6_+_97807014 3.061 ENSMUST00000043637.7
Mitf
microphthalmia-associated transcription factor
chr9_-_27155418 3.051 ENSMUST00000167074.1
ENSMUST00000034472.8
Jam3

junction adhesion molecule 3

chrX_+_109095359 3.047 ENSMUST00000033598.8
Sh3bgrl
SH3-binding domain glutamic acid-rich protein like
chr2_-_172940299 3.026 ENSMUST00000009143.7
Bmp7
bone morphogenetic protein 7
chr11_+_77216180 3.022 ENSMUST00000037912.5
ENSMUST00000156488.1
Ssh2

slingshot homolog 2 (Drosophila)

chr4_+_95967322 2.988 ENSMUST00000107083.1
Hook1
hook homolog 1 (Drosophila)
chr8_-_122699066 2.948 ENSMUST00000127984.1
Cbfa2t3
core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)
chrX_-_23365044 2.941 ENSMUST00000115313.1
Klhl13
kelch-like 13
chr18_-_10181792 2.924 ENSMUST00000067947.5
Rock1
Rho-associated coiled-coil containing protein kinase 1
chr8_+_87472805 2.891 ENSMUST00000180700.2
ENSMUST00000182174.1
ENSMUST00000181159.1
Gm2694


predicted gene 2694


chr8_-_105471481 2.882 ENSMUST00000014990.6
Tppp3
tubulin polymerization-promoting protein family member 3
chr14_-_122465677 2.880 ENSMUST00000039118.6
Zic5
zinc finger protein of the cerebellum 5
chr5_-_66618772 2.877 ENSMUST00000162994.1
ENSMUST00000159512.1
ENSMUST00000159786.1
Apbb2


amyloid beta (A4) precursor protein-binding, family B, member 2


chr10_+_93641041 2.862 ENSMUST00000020204.4
Ntn4
netrin 4
chr5_-_72587544 2.858 ENSMUST00000031124.4
Gm5868
predicted gene 5868
chr1_+_61638819 2.816 ENSMUST00000138768.1
ENSMUST00000075374.3
Pard3b

par-3 partitioning defective 3 homolog B (C. elegans)

chrX_+_143518576 2.812 ENSMUST00000033640.7
Pak3
p21 protein (Cdc42/Rac)-activated kinase 3
chrX_+_13071500 2.801 ENSMUST00000089302.4
Usp9x
ubiquitin specific peptidase 9, X chromosome
chr2_-_172043466 2.783 ENSMUST00000087950.3
Cbln4
cerebellin 4 precursor protein
chr4_+_137862270 2.781 ENSMUST00000130407.1
Ece1
endothelin converting enzyme 1
chr4_-_91399984 2.753 ENSMUST00000102799.3
Elavl2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr3_-_144720315 2.726 ENSMUST00000163279.1
Sh3glb1
SH3-domain GRB2-like B1 (endophilin)
chr5_-_140389188 2.709 ENSMUST00000031539.7
Snx8
sorting nexin 8
chr16_-_11176270 2.704 ENSMUST00000037633.8
Zc3h7a
zinc finger CCCH type containing 7 A
chrX_-_142390491 2.701 ENSMUST00000112904.1
ENSMUST00000112903.1
ENSMUST00000033634.4
Acsl4


acyl-CoA synthetase long-chain family member 4


chr18_-_47333311 2.687 ENSMUST00000126684.1
ENSMUST00000156422.1
Sema6a

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A

chr7_-_137314394 2.685 ENSMUST00000168203.1
ENSMUST00000106118.2
ENSMUST00000169486.2
ENSMUST00000033378.5
Ebf3



early B cell factor 3



chr13_+_97071627 2.684 ENSMUST00000042517.6
Fam169a
family with sequence similarity 169, member A
chr1_-_172590463 2.652 ENSMUST00000065679.6
Slamf8
SLAM family member 8
chrX_-_38252398 2.650 ENSMUST00000089056.3
ENSMUST00000089054.4
ENSMUST00000066498.7
Tmem255a


transmembrane protein 255A


chr19_+_47014672 2.637 ENSMUST00000037636.3
Ina
internexin neuronal intermediate filament protein, alpha
chr2_-_157204483 2.632 ENSMUST00000029170.7
Rbl1
retinoblastoma-like 1 (p107)
chr5_-_66618752 2.623 ENSMUST00000162366.1
Apbb2
amyloid beta (A4) precursor protein-binding, family B, member 2
chr17_-_89910449 2.623 ENSMUST00000086423.4
Gm10184
predicted pseudogene 10184
chr6_+_56017489 2.614 ENSMUST00000052827.4
Ppp1r17
protein phosphatase 1, regulatory subunit 17
chr9_-_39604124 2.611 ENSMUST00000042485.4
ENSMUST00000141370.1
AW551984

expressed sequence AW551984

chrX_-_106485214 2.603 ENSMUST00000039447.7
Fndc3c1
fibronectin type III domain containing 3C1
chr1_+_136624901 2.592 ENSMUST00000047734.8
ENSMUST00000112046.1
Zfp281

zinc finger protein 281

chr6_+_54264839 2.584 ENSMUST00000146114.1
Chn2
chimerin (chimaerin) 2
chr1_-_127677923 2.577 ENSMUST00000160616.1
Tmem163
transmembrane protein 163
chr8_+_31091593 2.559 ENSMUST00000161713.1
Dusp26
dual specificity phosphatase 26 (putative)
chr9_-_67760208 2.559 ENSMUST00000068526.5
M5C1000I18Rik
RIKEN cDNA M5C1000I18 gene
chr2_-_39190687 2.540 ENSMUST00000142872.1
ENSMUST00000038874.5
Scai

suppressor of cancer cell invasion

chr8_+_87472838 2.531 ENSMUST00000180806.2
Gm2694
predicted gene 2694
chr1_+_74791516 2.507 ENSMUST00000006718.8
Wnt10a
wingless related MMTV integration site 10a
chr3_+_125404072 2.505 ENSMUST00000173932.1
Ndst4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr7_-_141443314 2.493 ENSMUST00000106005.2
Lrdd
leucine-rich and death domain containing
chr10_+_67979592 2.488 ENSMUST00000105437.1
Rtkn2
rhotekin 2
chr10_+_26078255 2.477 ENSMUST00000041011.3
Gm9767
predicted gene 9767
chr10_+_67979569 2.468 ENSMUST00000118160.1
Rtkn2
rhotekin 2
chr15_-_98004634 2.457 ENSMUST00000131560.1
ENSMUST00000088355.5
Col2a1

collagen, type II, alpha 1

chr12_+_53248677 2.456 ENSMUST00000101432.2
Npas3
neuronal PAS domain protein 3
chr8_-_33385470 2.453 ENSMUST00000033991.6
ENSMUST00000033990.5
Wrn

Werner syndrome homolog (human)

chr1_+_6730135 2.451 ENSMUST00000155921.1
St18
suppression of tumorigenicity 18
chr5_+_45669907 2.451 ENSMUST00000117396.1
Ncapg
non-SMC condensin I complex, subunit G
chr11_+_62820469 2.418 ENSMUST00000108703.1
Trim16
tripartite motif-containing 16
chr6_+_7555053 2.396 ENSMUST00000090679.2
ENSMUST00000184986.1
Tac1

tachykinin 1

chr7_+_25152456 2.356 ENSMUST00000098678.1
D930028M14Rik
RIKEN cDNA D930028M14 gene
chrX_+_13071470 2.353 ENSMUST00000169594.2
Usp9x
ubiquitin specific peptidase 9, X chromosome
chr15_-_98004695 2.339 ENSMUST00000023123.8
Col2a1
collagen, type II, alpha 1
chr3_+_107036156 2.319 ENSMUST00000052718.3
Kcna3
potassium voltage-gated channel, shaker-related subfamily, member 3
chr17_-_53689266 2.300 ENSMUST00000024736.7
Sgol1
shugoshin-like 1 (S. pombe)
chr10_+_94514825 2.296 ENSMUST00000065060.5
Tmcc3
transmembrane and coiled coil domains 3
chr19_-_41743665 2.290 ENSMUST00000025993.3
Slit1
slit homolog 1 (Drosophila)
chr5_+_144545883 2.264 ENSMUST00000071782.6
Nptx2
neuronal pentraxin 2
chr10_-_114801364 2.262 ENSMUST00000061632.7
Trhde
TRH-degrading enzyme
chr5_-_123749371 2.262 ENSMUST00000182955.1
ENSMUST00000182489.1
ENSMUST00000050827.7
Rsrc2


arginine/serine-rich coiled-coil 2


chr10_+_98915117 2.253 ENSMUST00000020107.7
Atp2b1
ATPase, Ca++ transporting, plasma membrane 1
chr16_-_11176056 2.249 ENSMUST00000142389.1
ENSMUST00000138185.1
Zc3h7a

zinc finger CCCH type containing 7 A

chrX_+_112600526 2.227 ENSMUST00000113409.1
Zfp711
zinc finger protein 711
chr4_-_107683576 2.199 ENSMUST00000131776.1
Dmrtb1
DMRT-like family B with proline-rich C-terminal, 1
chr17_-_23745829 2.192 ENSMUST00000046525.8
Kremen2
kringle containing transmembrane protein 2
chr18_-_47368830 2.183 ENSMUST00000019791.7
ENSMUST00000115449.2
Sema6a

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A

chr19_+_20601958 2.179 ENSMUST00000087638.3
Aldh1a1
aldehyde dehydrogenase family 1, subfamily A1
chr14_+_64588112 2.161 ENSMUST00000181808.1
A930011O12Rik
RIKEN cDNA A930011O12 gene
chr3_-_33143227 2.154 ENSMUST00000108219.1
Pex5l
peroxisomal biogenesis factor 5-like
chr3_-_25212720 2.150 ENSMUST00000091289.3
Gm10259
predicted pseudogene 10259
chr13_+_104228929 2.122 ENSMUST00000070761.3
Cenpk
centromere protein K
chr13_-_114458720 2.118 ENSMUST00000022287.5
Fst
follistatin
chr8_-_41374602 2.104 ENSMUST00000110417.1
ENSMUST00000034000.8
ENSMUST00000143057.1
Asah1


N-acylsphingosine amidohydrolase 1


chr14_+_56668242 2.101 ENSMUST00000116468.1
Mphosph8
M-phase phosphoprotein 8
chrX_-_104671048 2.098 ENSMUST00000042070.5
Zdhhc15
zinc finger, DHHC domain containing 15
chr9_+_119402444 2.070 ENSMUST00000035093.8
ENSMUST00000165044.1
Acvr2b

activin receptor IIB

chr14_+_31019125 2.052 ENSMUST00000112095.1
ENSMUST00000112098.3
ENSMUST00000112106.1
ENSMUST00000146325.1
Pbrm1



polybromo 1



chr18_-_46525940 2.038 ENSMUST00000036226.5
Fem1c
fem-1 homolog c (C.elegans)
chr11_-_6475992 2.038 ENSMUST00000179343.1
Purb
purine rich element binding protein B
chr2_+_91526756 2.036 ENSMUST00000111338.3
Ckap5
cytoskeleton associated protein 5
chr3_+_125404292 2.031 ENSMUST00000144344.1
Ndst4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr18_+_74442551 2.031 ENSMUST00000121875.1
Myo5b
myosin VB
chr4_-_97584605 2.016 ENSMUST00000107067.1
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr16_-_16599978 2.012 ENSMUST00000162671.1
Fgd4
FYVE, RhoGEF and PH domain containing 4
chr7_+_142471838 2.009 ENSMUST00000038946.2
Lsp1
lymphocyte specific 1
chr8_-_87959560 1.989 ENSMUST00000109655.2
Zfp423
zinc finger protein 423
chr14_+_31019183 1.988 ENSMUST00000052239.5
Pbrm1
polybromo 1
chrX_-_142390334 1.983 ENSMUST00000112907.1
Acsl4
acyl-CoA synthetase long-chain family member 4
chr17_+_21962552 1.978 ENSMUST00000055349.8
ENSMUST00000153985.1
Zfp943

zinc finger prtoein 943

chr4_-_97584612 1.971 ENSMUST00000107068.2
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr17_-_21962451 1.958 ENSMUST00000091879.5
Zfp942
zinc finger protein 942
chr12_-_85097080 1.951 ENSMUST00000177289.2
Prox2
prospero homeobox 2
chr18_-_35649349 1.947 ENSMUST00000025211.4
Mzb1
marginal zone B and B1 cell-specific protein 1
chr3_-_33143025 1.945 ENSMUST00000108226.1
Pex5l
peroxisomal biogenesis factor 5-like
chr1_-_84284423 1.944 ENSMUST00000176720.1
Pid1
phosphotyrosine interaction domain containing 1
chr10_+_67979709 1.942 ENSMUST00000117086.1
Rtkn2
rhotekin 2
chr12_+_11265867 1.935 ENSMUST00000020931.5
Smc6
structural maintenance of chromosomes 6
chr9_-_70657121 1.929 ENSMUST00000049031.5
Fam63b
family with sequence similarity 63, member B
chr17_-_35027909 1.928 ENSMUST00000040151.2
Sapcd1
suppressor APC domain containing 1
chr15_-_102004305 1.916 ENSMUST00000023952.8
Krt8
keratin 8
chr18_+_60925612 1.912 ENSMUST00000102888.3
ENSMUST00000025519.4
Camk2a

calcium/calmodulin-dependent protein kinase II alpha

chr11_-_64436653 1.904 ENSMUST00000177999.1
F930015N05Rik
RIKEN cDNA F930015N05 gene
chr18_+_74442500 1.897 ENSMUST00000074157.6
Myo5b
myosin VB
chr8_-_84937347 1.888 ENSMUST00000109741.2
ENSMUST00000119820.1
Mast1

microtubule associated serine/threonine kinase 1

chr10_-_62231208 1.886 ENSMUST00000047883.9
Tspan15
tetraspanin 15
chr7_+_4925802 1.880 ENSMUST00000057612.7
Ssc5d
scavenger receptor cysteine rich domain containing (5 domains)
chr10_-_85127977 1.875 ENSMUST00000050813.2
Mterfd3
MTERF domain containing 3
chr12_+_72441852 1.872 ENSMUST00000162159.1
Lrrc9
leucine rich repeat containing 9
chr7_-_102477902 1.863 ENSMUST00000061482.5
Olfr543
olfactory receptor 543
chr14_+_68083853 1.856 ENSMUST00000022639.7
Nefl
neurofilament, light polypeptide
chr2_+_155133501 1.853 ENSMUST00000029126.8
ENSMUST00000109685.1
Itch

itchy, E3 ubiquitin protein ligase

chr13_+_104178797 1.852 ENSMUST00000022225.5
ENSMUST00000069187.5
Trim23

tripartite motif-containing 23

chr8_+_40423786 1.846 ENSMUST00000049389.4
ENSMUST00000128166.1
ENSMUST00000167766.1
Zdhhc2


zinc finger, DHHC domain containing 2


chr10_-_94944578 1.843 ENSMUST00000099337.3
Plxnc1
plexin C1
chr11_+_29373618 1.838 ENSMUST00000040182.6
ENSMUST00000109477.1
Ccdc88a

coiled coil domain containing 88A

chr6_-_12749193 1.838 ENSMUST00000046121.6
ENSMUST00000172356.1
Thsd7a

thrombospondin, type I, domain containing 7A

chr3_+_29082539 1.831 ENSMUST00000119598.1
ENSMUST00000118531.1
Egfem1

EGF-like and EMI domain containing 1

chrX_+_71050160 1.831 ENSMUST00000082088.3
ENSMUST00000114629.3
Mamld1

mastermind-like domain containing 1

chr14_-_96519067 1.830 ENSMUST00000022666.7
Klhl1
kelch-like 1
chr4_-_97778042 1.825 ENSMUST00000146447.1
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr10_+_26772477 1.824 ENSMUST00000039557.7
Arhgap18
Rho GTPase activating protein 18
chr3_+_28781305 1.815 ENSMUST00000060500.7
Eif5a2
eukaryotic translation initiation factor 5A2
chr7_+_142460834 1.813 ENSMUST00000018963.4
ENSMUST00000105967.1
Lsp1

lymphocyte specific 1

chr17_-_35702297 1.812 ENSMUST00000135078.1
Ddr1
discoidin domain receptor family, member 1
chr9_+_102720287 1.811 ENSMUST00000130602.1
Amotl2
angiomotin-like 2
chr12_-_98737405 1.801 ENSMUST00000170188.1
Ptpn21
protein tyrosine phosphatase, non-receptor type 21
chr1_-_71103146 1.799 ENSMUST00000027393.7
Bard1
BRCA1 associated RING domain 1
chr19_-_29805989 1.798 ENSMUST00000177155.1
ENSMUST00000059484.7
9930021J03Rik

RIKEN cDNA 9930021J03 gene

chr1_-_10232670 1.790 ENSMUST00000088615.4
ENSMUST00000131556.1
Arfgef1

ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited)

chr11_+_35769462 1.788 ENSMUST00000018990.7
Pank3
pantothenate kinase 3
chrX_+_143664290 1.776 ENSMUST00000112868.1
Pak3
p21 protein (Cdc42/Rac)-activated kinase 3
chr14_+_14703025 1.769 ENSMUST00000057015.6
Slc4a7
solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr13_-_117025505 1.764 ENSMUST00000022239.6
Parp8
poly (ADP-ribose) polymerase family, member 8
chrX_-_162829379 1.763 ENSMUST00000041370.4
ENSMUST00000112316.2
ENSMUST00000112315.1
Txlng


taxilin gamma


chr13_-_98891036 1.762 ENSMUST00000109399.2
Tnpo1
transportin 1
chr17_+_33638056 1.762 ENSMUST00000052079.7
Pram1
PML-RAR alpha-regulated adaptor molecule 1
chr5_+_65764073 1.756 ENSMUST00000138239.1
ENSMUST00000087264.3
N4bp2

NEDD4 binding protein 2

chr10_+_80494835 1.754 ENSMUST00000051773.8
Onecut3
one cut domain, family member 3
chr17_+_25717171 1.752 ENSMUST00000172002.1
Gng13
guanine nucleotide binding protein (G protein), gamma 13
chr2_-_127133909 1.749 ENSMUST00000110387.3
Ncaph
non-SMC condensin I complex, subunit H
chr8_+_79639618 1.741 ENSMUST00000173078.1
ENSMUST00000173286.1
Otud4

OTU domain containing 4

chr14_-_104467984 1.738 ENSMUST00000053016.8
Pou4f1
POU domain, class 4, transcription factor 1
chr4_-_82859571 1.735 ENSMUST00000156055.1
ENSMUST00000030110.8
Zdhhc21

zinc finger, DHHC domain containing 21

chr17_-_25797032 1.733 ENSMUST00000165838.1
ENSMUST00000002344.6
Metrn

meteorin, glial cell differentiation regulator

chrX_-_37110257 1.732 ENSMUST00000076265.6
Upf3b
UPF3 regulator of nonsense transcripts homolog B (yeast)
chr9_-_97018823 1.731 ENSMUST00000055433.4
Spsb4
splA/ryanodine receptor domain and SOCS box containing 4

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 5.7 GO:0003349 epicardium-derived cardiac endothelial cell differentiation(GO:0003349)
1.7 5.2 GO:0021698 cerebellar cortex structural organization(GO:0021698)
1.4 7.1 GO:0007386 compartment pattern specification(GO:0007386)
1.2 3.5 GO:0070649 meiotic chromosome movement towards spindle pole(GO:0016344) formin-nucleated actin cable assembly(GO:0070649)
1.1 3.4 GO:0010814 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
1.0 3.1 GO:1903048 regulation of acetylcholine-gated cation channel activity(GO:1903048)
1.0 3.0 GO:0072076 hyaluranon cable assembly(GO:0036118) nephrogenic mesenchyme development(GO:0072076) negative regulation of glomerular mesangial cell proliferation(GO:0072125) negative regulation of glomerulus development(GO:0090194) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
1.0 6.9 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
1.0 3.9 GO:2001274 negative regulation of glucose import in response to insulin stimulus(GO:2001274)
0.9 7.4 GO:0016321 female meiosis chromosome segregation(GO:0016321)
0.9 2.8 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.9 3.5 GO:0046878 positive regulation of saliva secretion(GO:0046878)
0.9 2.6 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.8 3.3 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.8 7.4 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.8 2.3 GO:0072382 minus-end-directed vesicle transport along microtubule(GO:0072382)
0.8 0.8 GO:0034146 toll-like receptor 5 signaling pathway(GO:0034146)
0.8 3.8 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.7 6.0 GO:0098712 L-glutamate import across plasma membrane(GO:0098712)
0.7 2.1 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.7 2.7 GO:2000508 regulation of dendritic cell chemotaxis(GO:2000508)
0.7 2.0 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.7 3.9 GO:0032439 endosome localization(GO:0032439)
0.7 3.3 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.6 3.2 GO:0040009 regulation of growth rate(GO:0040009)
0.6 5.1 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.6 3.8 GO:1901525 negative regulation of macromitophagy(GO:1901525) regulation of mitophagy in response to mitochondrial depolarization(GO:1904923)
0.6 1.9 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.6 5.4 GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.6 3.0 GO:1990034 calcium ion export from cell(GO:1990034)
0.6 1.8 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.6 0.6 GO:0070094 positive regulation of glucagon secretion(GO:0070094)
0.6 4.1 GO:0051461 protein import into peroxisome matrix, docking(GO:0016560) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.6 2.9 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.6 2.2 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.6 4.5 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.6 6.7 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.5 2.2 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.5 0.5 GO:0060423 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492)
0.5 1.0 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.5 1.0 GO:2000373 regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
0.5 1.9 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.5 3.3 GO:0015791 polyol transport(GO:0015791)
0.5 0.9 GO:0048496 maintenance of organ identity(GO:0048496)
0.5 4.1 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.4 2.2 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.4 1.8 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)
0.4 0.9 GO:0010996 response to auditory stimulus(GO:0010996)
0.4 2.6 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.4 1.3 GO:0009174 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.4 1.3 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.4 2.9 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.4 5.0 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.4 1.2 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.4 4.6 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.4 3.3 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.4 2.0 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.4 0.8 GO:0061054 dermatome development(GO:0061054) regulation of dermatome development(GO:0061183)
0.4 1.6 GO:0019323 pentose catabolic process(GO:0019323)
0.4 1.2 GO:0032650 regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730) cardiac cell fate determination(GO:0060913)
0.4 2.0 GO:0061314 Notch signaling involved in heart development(GO:0061314)
0.4 2.0 GO:0019230 proprioception(GO:0019230)
0.4 1.2 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.4 5.0 GO:0051127 positive regulation of actin nucleation(GO:0051127)
0.4 0.8 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.4 3.4 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.4 2.6 GO:0060923 cardiac muscle cell fate commitment(GO:0060923)
0.4 2.6 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.4 2.2 GO:0060022 hard palate development(GO:0060022)
0.4 1.8 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.4 1.1 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.4 4.3 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.4 1.1 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.4 3.9 GO:0048733 sebaceous gland development(GO:0048733)
0.4 2.8 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.4 0.7 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.3 1.7 GO:0006537 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.3 0.3 GO:1902263 apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
0.3 1.0 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
0.3 1.4 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.3 1.0 GO:0048162 preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162)
0.3 4.0 GO:0060836 lymphatic endothelial cell differentiation(GO:0060836)
0.3 3.7 GO:0001977 renal system process involved in regulation of blood volume(GO:0001977)
0.3 2.3 GO:0021747 cochlear nucleus development(GO:0021747)
0.3 1.3 GO:0060032 notochord regression(GO:0060032)
0.3 3.3 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.3 2.3 GO:0033563 dorsal/ventral axon guidance(GO:0033563)
0.3 2.0 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.3 1.3 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.3 3.5 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.3 1.9 GO:2000483 detection of bacterium(GO:0016045) detection of other organism(GO:0098543) negative regulation of interleukin-8 secretion(GO:2000483)
0.3 1.9 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.3 0.9 GO:0035523 protein K29-linked deubiquitination(GO:0035523) protein K6-linked deubiquitination(GO:0044313)
0.3 0.9 GO:1903279 regulation of calcium:sodium antiporter activity(GO:1903279)
0.3 1.2 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.3 1.8 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.3 0.9 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.3 0.6 GO:1904058 positive regulation of sensory perception of pain(GO:1904058)
0.3 1.8 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.3 1.8 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.3 0.9 GO:0046544 regulation of natural killer cell proliferation(GO:0032817) positive regulation of natural killer cell proliferation(GO:0032819) development of secondary male sexual characteristics(GO:0046544)
0.3 1.2 GO:0097623 potassium ion export across plasma membrane(GO:0097623) regulation of potassium ion export(GO:1902302)
0.3 0.6 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.3 0.3 GO:0060295 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108) regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.3 1.2 GO:0016240 autophagosome docking(GO:0016240)
0.3 0.9 GO:0021759 globus pallidus development(GO:0021759)
0.3 1.4 GO:0002634 regulation of germinal center formation(GO:0002634)
0.3 0.6 GO:0008594 photoreceptor cell morphogenesis(GO:0008594)
0.3 3.1 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.3 1.1 GO:0021764 amygdala development(GO:0021764)
0.3 0.8 GO:0046381 CMP-N-acetylneuraminate metabolic process(GO:0046381)
0.3 0.8 GO:0035984 response to trichostatin A(GO:0035983) cellular response to trichostatin A(GO:0035984)
0.3 1.1 GO:0060025 regulation of synaptic activity(GO:0060025)
0.3 12.6 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.3 1.9 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.3 6.5 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.3 0.5 GO:0097709 connective tissue replacement(GO:0097709) regulation of connective tissue replacement(GO:1905203)
0.3 0.8 GO:0045658 eosinophil differentiation(GO:0030222) regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.3 2.1 GO:0051798 positive regulation of hair follicle development(GO:0051798)
0.3 0.8 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.3 1.0 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.3 2.9 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.3 8.3 GO:0007608 sensory perception of smell(GO:0007608)
0.3 2.6 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.3 1.3 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
0.3 1.0 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.3 0.8 GO:0030070 insulin processing(GO:0030070)
0.3 3.8 GO:0007220 Notch receptor processing(GO:0007220)
0.3 3.8 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.2 1.5 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.2 1.7 GO:0098535 positive regulation of centriole replication(GO:0046601) de novo centriole assembly(GO:0098535)
0.2 1.2 GO:0090383 phagosome acidification(GO:0090383)
0.2 0.7 GO:1903998 regulation of eating behavior(GO:1903998)
0.2 0.7 GO:0044782 cilium organization(GO:0044782)
0.2 2.1 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.2 0.2 GO:0061009 common bile duct development(GO:0061009)
0.2 0.9 GO:1903028 regulation of opsonization(GO:1903027) positive regulation of opsonization(GO:1903028)
0.2 2.1 GO:0071420 cellular response to histamine(GO:0071420)
0.2 0.5 GO:0010512 negative regulation of phosphatidylinositol biosynthetic process(GO:0010512)
0.2 0.7 GO:0021649 vestibulocochlear nerve morphogenesis(GO:0021648) vestibulocochlear nerve structural organization(GO:0021649) ganglion morphogenesis(GO:0061552) sensory neuron axon guidance(GO:0097374) dorsal root ganglion morphogenesis(GO:1904835)
0.2 0.9 GO:0048105 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
0.2 4.6 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.2 0.5 GO:0060744 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.2 1.4 GO:0043651 linoleic acid metabolic process(GO:0043651)
0.2 1.1 GO:0071600 otic vesicle morphogenesis(GO:0071600)
0.2 1.4 GO:0097680 double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.2 0.4 GO:1903207 neuron death in response to hydrogen peroxide(GO:0036476) regulation of hydrogen peroxide-induced neuron death(GO:1903207) negative regulation of hydrogen peroxide-induced neuron death(GO:1903208)
0.2 1.8 GO:0043313 regulation of neutrophil degranulation(GO:0043313) regulation of neutrophil activation(GO:1902563)
0.2 1.5 GO:0046549 phenol-containing compound catabolic process(GO:0019336) retinal cone cell development(GO:0046549)
0.2 1.5 GO:0007144 female meiosis I(GO:0007144)
0.2 1.1 GO:0001865 NK T cell differentiation(GO:0001865) regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138)
0.2 0.4 GO:1902162 regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162)
0.2 3.2 GO:0042711 maternal behavior(GO:0042711)
0.2 4.2 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.2 0.6 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.2 1.9 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.2 0.4 GO:0007066 female meiosis sister chromatid cohesion(GO:0007066)
0.2 1.9 GO:0030035 microspike assembly(GO:0030035)
0.2 1.5 GO:1990504 dense core granule exocytosis(GO:1990504)
0.2 0.6 GO:1901355 response to rapamycin(GO:1901355)
0.2 0.8 GO:0060903 positive regulation of meiosis I(GO:0060903)
0.2 0.6 GO:1903061 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051) regulation of protein lipidation(GO:1903059) positive regulation of protein lipidation(GO:1903061)
0.2 0.8 GO:0061110 dense core granule biogenesis(GO:0061110)
0.2 3.6 GO:0006312 mitotic recombination(GO:0006312)
0.2 0.6 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.2 8.9 GO:0045022 early endosome to late endosome transport(GO:0045022)
0.2 0.6 GO:0042100 B cell proliferation(GO:0042100)
0.2 0.8 GO:0031860 telomeric 3' overhang formation(GO:0031860) negative regulation of telomere capping(GO:1904354)
0.2 1.2 GO:0098964 dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964)
0.2 1.5 GO:0060736 prostate gland growth(GO:0060736)
0.2 1.1 GO:0045218 zonula adherens maintenance(GO:0045218)
0.2 2.5 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.2 0.9 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.2 0.8 GO:0002934 desmosome organization(GO:0002934)
0.2 2.2 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.2 1.1 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.2 1.6 GO:0010587 miRNA catabolic process(GO:0010587)
0.2 0.7 GO:0007256 activation of JNKK activity(GO:0007256)
0.2 0.7 GO:0070859 positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
0.2 0.5 GO:0098885 actin filament bundle distribution(GO:0070650) modification of postsynaptic actin cytoskeleton(GO:0098885)
0.2 1.4 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.2 0.3 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
0.2 1.0 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.2 1.9 GO:0070922 small RNA loading onto RISC(GO:0070922)
0.2 0.2 GO:0090594 wound healing involved in inflammatory response(GO:0002246) inflammatory response to wounding(GO:0090594)
0.2 1.9 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.2 0.3 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.2 0.3 GO:0006041 glucosamine metabolic process(GO:0006041)
0.2 1.5 GO:0046085 adenosine metabolic process(GO:0046085)
0.2 1.0 GO:0016266 O-glycan processing(GO:0016266)
0.2 1.0 GO:0045629 positive regulation of T-helper 1 cell differentiation(GO:0045627) negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.2 0.8 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.2 0.5 GO:1905049 negative regulation of metalloendopeptidase activity(GO:1904684) negative regulation of metallopeptidase activity(GO:1905049)
0.2 0.3 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020)
0.2 1.3 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.2 0.3 GO:0072053 renal inner medulla development(GO:0072053) renal outer medulla development(GO:0072054)
0.2 1.6 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.2 0.3 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.2 2.9 GO:0007638 mechanosensory behavior(GO:0007638)
0.2 0.2 GO:0048819 regulation of hair follicle maturation(GO:0048819) regulation of catagen(GO:0051794)
0.2 5.4 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.1 0.4 GO:0045176 apical protein localization(GO:0045176)
0.1 0.7 GO:0000050 urea cycle(GO:0000050) urea metabolic process(GO:0019627)
0.1 0.7 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.1 0.9 GO:0051409 response to nitrosative stress(GO:0051409)
0.1 0.7 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.1 2.2 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 0.4 GO:0019372 lipoxygenase pathway(GO:0019372)
0.1 0.6 GO:0006680 glucosylceramide catabolic process(GO:0006680) positive regulation of endodeoxyribonuclease activity(GO:0032079)
0.1 1.3 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 2.5 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.1 1.1 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.1 0.4 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.1 0.6 GO:0015889 cobalamin transport(GO:0015889)
0.1 0.8 GO:1901911 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 1.0 GO:0019240 citrulline biosynthetic process(GO:0019240)
0.1 0.5 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.1 1.5 GO:0001711 endodermal cell fate commitment(GO:0001711)
0.1 0.8 GO:1904816 positive regulation of protein localization to chromosome, telomeric region(GO:1904816)
0.1 0.8 GO:0006817 phosphate ion transport(GO:0006817)
0.1 0.4 GO:0050915 sensory perception of sour taste(GO:0050915)
0.1 0.6 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.1 1.0 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.1 1.5 GO:0070995 NADPH oxidation(GO:0070995)
0.1 1.1 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.1 1.7 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)
0.1 1.0 GO:0009435 NAD biosynthetic process(GO:0009435)
0.1 1.1 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.1 1.2 GO:2001273 regulation of glucose import in response to insulin stimulus(GO:2001273)
0.1 1.0 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.1 1.3 GO:0031268 pseudopodium organization(GO:0031268)
0.1 0.4 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1 0.5 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.1 0.5 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.1 0.5 GO:0035754 B cell chemotaxis(GO:0035754)
0.1 1.4 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 1.4 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1 1.4 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.1 1.3 GO:0003413 chondrocyte differentiation involved in endochondral bone morphogenesis(GO:0003413)
0.1 1.0 GO:1900194 negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194)
0.1 0.6 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.1 1.4 GO:0010715 regulation of extracellular matrix disassembly(GO:0010715) collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.1 0.5 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.1 2.0 GO:0015693 magnesium ion transport(GO:0015693)
0.1 0.9 GO:0097264 self proteolysis(GO:0097264)
0.1 0.3 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.1 0.8 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.1 0.2 GO:2000850 negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
0.1 0.7 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.1 1.5 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.1 2.7 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.1 0.4 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.1 2.9 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.1 0.7 GO:0015074 DNA integration(GO:0015074)
0.1 0.8 GO:0090394 negative regulation of excitatory postsynaptic potential(GO:0090394)
0.1 0.3 GO:0071415 cellular response to purine-containing compound(GO:0071415)
0.1 2.2 GO:0061157 mRNA destabilization(GO:0061157)
0.1 0.3 GO:0045819 plasmacytoid dendritic cell activation(GO:0002270) positive regulation of toll-like receptor 2 signaling pathway(GO:0034137) positive regulation of glycogen catabolic process(GO:0045819)
0.1 0.8 GO:0060033 anatomical structure regression(GO:0060033)
0.1 0.6 GO:0006172 ADP biosynthetic process(GO:0006172)
0.1 1.6 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.3 GO:0055070 copper ion homeostasis(GO:0055070)
0.1 0.6 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.1 2.9 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.1 0.3 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.1 0.7 GO:0060019 radial glial cell differentiation(GO:0060019)
0.1 0.1 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.1 0.7 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 2.1 GO:0044030 regulation of DNA methylation(GO:0044030)
0.1 1.3 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.1 1.6 GO:0043045 DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.1 1.4 GO:0032460 negative regulation of protein oligomerization(GO:0032460) negative regulation of protein homooligomerization(GO:0032463)
0.1 2.3 GO:0045103 intermediate filament-based process(GO:0045103)
0.1 0.3 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.1 0.7 GO:0006983 ER overload response(GO:0006983)
0.1 0.5 GO:0072697 protein localization to cell cortex(GO:0072697)
0.1 0.9 GO:0072189 ureter development(GO:0072189)
0.1 1.2 GO:0048368 lateral mesoderm development(GO:0048368)
0.1 0.2 GO:1903334 positive regulation of protein folding(GO:1903334)
0.1 0.2 GO:0030321 transepithelial chloride transport(GO:0030321)
0.1 0.7 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.1 0.3 GO:0006344 maintenance of chromatin silencing(GO:0006344)
0.1 2.6 GO:0043171 peptide catabolic process(GO:0043171)
0.1 0.4 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.1 0.9 GO:0048853 forebrain morphogenesis(GO:0048853)
0.1 0.3 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.1 0.5 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.1 0.2 GO:0071941 nitrogen cycle metabolic process(GO:0071941)
0.1 0.5 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.1 0.3 GO:0046006 positive regulation of activated T cell proliferation(GO:0042104) regulation of activated T cell proliferation(GO:0046006)
0.1 0.3 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.1 0.3 GO:0070305 response to cGMP(GO:0070305) cellular response to cGMP(GO:0071321) membrane depolarization during SA node cell action potential(GO:0086046)
0.1 0.6 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1 1.1 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.1 0.9 GO:2000254 regulation of male germ cell proliferation(GO:2000254)
0.1 1.4 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.1 0.4 GO:2000059 negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000059)
0.1 0.4 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1 1.8 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.1 0.3 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.1 0.8 GO:0030388 fructose 6-phosphate metabolic process(GO:0006002) fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 0.6 GO:0008334 histone mRNA metabolic process(GO:0008334)
0.1 1.7 GO:0007020 microtubule nucleation(GO:0007020)
0.1 0.4 GO:0060482 lobar bronchus development(GO:0060482)
0.1 0.4 GO:0090527 actin filament reorganization(GO:0090527)
0.1 0.6 GO:0014029 neural crest formation(GO:0014029)
0.1 2.0 GO:0035329 hippo signaling(GO:0035329)
0.1 0.6 GO:0022617 extracellular matrix disassembly(GO:0022617)
0.1 0.4 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.1 1.5 GO:0000132 establishment of mitotic spindle orientation(GO:0000132) establishment of mitotic spindle localization(GO:0040001)
0.1 1.3 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.1 0.9 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.1 0.2 GO:0072103 renal system vasculature morphogenesis(GO:0061438) kidney vasculature morphogenesis(GO:0061439) glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104)
0.1 0.2 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.1 1.3 GO:0002011 morphogenesis of an epithelial sheet(GO:0002011)
0.1 0.7 GO:0006415 translational termination(GO:0006415)
0.1 0.4 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.1 0.9 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.1 0.4 GO:0006544 glycine metabolic process(GO:0006544)
0.1 0.7 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.1 0.9 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.1 0.6 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 0.4 GO:0006020 inositol metabolic process(GO:0006020)
0.1 0.6 GO:0036297 interstrand cross-link repair(GO:0036297)
0.1 0.4 GO:0071294 cellular response to zinc ion(GO:0071294)
0.1 1.0 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.1 8.3 GO:0050821 protein stabilization(GO:0050821)
0.1 1.0 GO:0034389 lipid particle organization(GO:0034389)
0.1 0.6 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.1 0.7 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.1 0.5 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.1 1.1 GO:0006491 N-glycan processing(GO:0006491)
0.1 0.7 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.1 1.2 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.1 1.4 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.1 0.5 GO:0046512 sphingosine biosynthetic process(GO:0046512) sphingoid biosynthetic process(GO:0046520)
0.1 0.4 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.1 0.4 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.1 2.1 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.1 0.2 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.1 0.7 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.1 1.1 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.1 0.2 GO:0046541 saliva secretion(GO:0046541)
0.0 1.3 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.0 0.8 GO:0098868 endochondral bone growth(GO:0003416) bone growth(GO:0098868)
0.0 0.3 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.0 0.1 GO:0007161 calcium-independent cell-matrix adhesion(GO:0007161)
0.0 0.2 GO:0035148 tube formation(GO:0035148)
0.0 0.2 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.4 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.6 GO:0046856 phospholipid dephosphorylation(GO:0046839) phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.2 GO:0042359 vitamin D metabolic process(GO:0042359)
0.0 0.5 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.4 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.5 GO:0061245 establishment or maintenance of apical/basal cell polarity(GO:0035088) establishment or maintenance of bipolar cell polarity(GO:0061245)
0.0 0.6 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 1.0 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.7 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 1.1 GO:0090307 mitotic spindle assembly(GO:0090307)
0.0 0.1 GO:1990859 cellular response to endothelin(GO:1990859)
0.0 0.1 GO:0070944 neutrophil mediated killing of bacterium(GO:0070944)
0.0 0.5 GO:0014047 glutamate secretion(GO:0014047)
0.0 1.1 GO:1900449 regulation of glutamate receptor signaling pathway(GO:1900449)
0.0 0.3 GO:0002693 positive regulation of cellular extravasation(GO:0002693)
0.0 1.0 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.8 GO:0001569 patterning of blood vessels(GO:0001569)
0.0 0.2 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.0 0.5 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 1.5 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 0.8 GO:0016180 snRNA processing(GO:0016180)
0.0 0.3 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.0 0.2 GO:0036120 response to platelet-derived growth factor(GO:0036119) cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.0 0.1 GO:2001053 regulation of mesenchymal cell apoptotic process(GO:2001053) negative regulation of mesenchymal cell apoptotic process(GO:2001054)
0.0 0.6 GO:0007340 acrosome reaction(GO:0007340)
0.0 1.0 GO:0031960 response to corticosteroid(GO:0031960) response to glucocorticoid(GO:0051384)
0.0 0.4 GO:0001573 ganglioside metabolic process(GO:0001573)
0.0 0.3 GO:0030071 regulation of mitotic metaphase/anaphase transition(GO:0030071) regulation of metaphase/anaphase transition of cell cycle(GO:1902099)
0.0 0.2 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.0 1.3 GO:0043488 regulation of mRNA stability(GO:0043488)
0.0 0.1 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.0 1.2 GO:0048278 vesicle docking(GO:0048278)
0.0 0.1 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.0 0.1 GO:0031547 brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
0.0 0.1 GO:0046519 sphingoid metabolic process(GO:0046519)
0.0 0.2 GO:0034390 smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391)
0.0 0.9 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.2 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.7 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.1 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.2 GO:0051014 actin filament severing(GO:0051014)
0.0 0.4 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209) negative regulation of sequestering of calcium ion(GO:0051283)
0.0 0.6 GO:0097320 membrane tubulation(GO:0097320)
0.0 0.5 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.0 0.2 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.1 GO:0019805 quinolinate biosynthetic process(GO:0019805) quinolinate metabolic process(GO:0046874)
0.0 0.1 GO:0002756 MyD88-independent toll-like receptor signaling pathway(GO:0002756)
0.0 0.3 GO:0002385 organ or tissue specific immune response(GO:0002251) mucosal immune response(GO:0002385)
0.0 0.1 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.3 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.0 0.1 GO:0046077 dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate metabolic process(GO:0009138) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077)
0.0 0.1 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.8 GO:0051647 nucleus localization(GO:0051647)
0.0 0.2 GO:0003341 cilium movement(GO:0003341)
0.0 0.2 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.3 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.0 0.4 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 0.2 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 0.3 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.2 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.0 0.3 GO:0003016 respiratory system process(GO:0003016)
0.0 0.9 GO:0045727 positive regulation of translation(GO:0045727)
0.0 1.0 GO:1903051 negative regulation of proteolysis involved in cellular protein catabolic process(GO:1903051)
0.0 0.2 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.0 0.1 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.1 GO:0046098 guanine metabolic process(GO:0046098)
0.0 1.5 GO:0007286 spermatid development(GO:0007286)
0.0 0.5 GO:0051591 response to cAMP(GO:0051591)
0.0 0.1 GO:0050812 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0 0.1 GO:0016584 nucleosome positioning(GO:0016584)
0.0 1.8 GO:0016331 morphogenesis of embryonic epithelium(GO:0016331)
0.0 0.1 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.0 0.2 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.3 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.0 0.3 GO:2001222 regulation of neuron migration(GO:2001222)
0.0 0.2 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 1.3 GO:0051028 mRNA transport(GO:0051028)
0.0 0.1 GO:0048875 chemical homeostasis within a tissue(GO:0048875)
0.0 0.2 GO:0009880 embryonic pattern specification(GO:0009880)
0.0 0.1 GO:0008272 sulfate transport(GO:0008272)
0.0 1.1 GO:0007224 smoothened signaling pathway(GO:0007224)
0.0 0.2 GO:0051443 positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.0 0.3 GO:1903077 negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.0 0.3 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.0 0.1 GO:0006825 copper ion transport(GO:0006825)
0.0 0.1 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.0 0.3 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.0 0.2 GO:0046686 response to cadmium ion(GO:0046686)
0.0 0.0 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.0 0.3 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.0 0.1 GO:0001996 regulation of systemic arterial blood pressure by norepinephrine-epinephrine(GO:0001993) positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996) positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 6.9 GO:0032133 interphase microtubule organizing center(GO:0031021) chromosome passenger complex(GO:0032133)
1.0 4.1 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.9 6.5 GO:0070695 FHF complex(GO:0070695)
0.9 2.6 GO:0099573 glutamatergic postsynaptic density(GO:0099573)
0.7 3.4 GO:0033093 Weibel-Palade body(GO:0033093)
0.6 1.9 GO:0035061 interchromatin granule(GO:0035061)
0.6 5.9 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.6 1.7 GO:0000799 nuclear condensin complex(GO:0000799)
0.5 3.3 GO:0045179 apical cortex(GO:0045179)
0.5 3.1 GO:0033010 paranodal junction(GO:0033010)
0.5 4.5 GO:0005883 neurofilament(GO:0005883)
0.5 2.9 GO:0070531 BRCA1-A complex(GO:0070531)
0.5 2.5 GO:0032389 MutLalpha complex(GO:0032389)
0.4 1.3 GO:0005940 septin ring(GO:0005940)
0.4 4.8 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.4 1.8 GO:0061689 tricellular tight junction(GO:0061689)
0.4 2.5 GO:0000796 condensin complex(GO:0000796)
0.3 2.7 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.3 2.9 GO:0097427 microtubule bundle(GO:0097427)
0.3 4.1 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.3 0.9 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.3 1.2 GO:0008623 CHRAC(GO:0008623)
0.3 0.9 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.3 0.9 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.3 1.7 GO:0098536 deuterosome(GO:0098536)
0.3 2.6 GO:0097165 nuclear stress granule(GO:0097165)
0.3 3.1 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.3 1.3 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.3 1.8 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.2 0.7 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.2 1.0 GO:0060187 cell pole(GO:0060187)
0.2 1.5 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.2 1.4 GO:0000938 GARP complex(GO:0000938)
0.2 1.1 GO:0071203 WASH complex(GO:0071203)
0.2 1.4 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807)
0.2 2.9 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.2 0.9 GO:0000438 core TFIIH complex portion of holo TFIIH complex(GO:0000438)
0.2 2.6 GO:0045095 keratin filament(GO:0045095)
0.2 3.2 GO:0005662 DNA replication factor A complex(GO:0005662)
0.2 9.2 GO:0031941 filamentous actin(GO:0031941)
0.2 3.0 GO:1902711 GABA-A receptor complex(GO:1902711)
0.2 1.0 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.2 0.6 GO:0005899 insulin receptor complex(GO:0005899)
0.2 0.8 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.2 6.5 GO:0030904 retromer complex(GO:0030904)
0.2 1.6 GO:0032591 dendritic spine membrane(GO:0032591)
0.2 1.3 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.2 0.9 GO:1990037 Lewy body core(GO:1990037)
0.2 1.6 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.2 1.5 GO:0070578 RISC-loading complex(GO:0070578)
0.2 1.0 GO:0005663 DNA replication factor C complex(GO:0005663)
0.2 6.0 GO:0030673 axolemma(GO:0030673)
0.2 0.5 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.2 1.2 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.2 15.5 GO:0016605 PML body(GO:0016605)
0.1 1.5 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.1 0.4 GO:0000802 transverse filament(GO:0000802)
0.1 0.7 GO:0070876 SOSS complex(GO:0070876)
0.1 0.7 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.1 2.7 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 3.1 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 0.9 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 4.6 GO:0090544 BAF-type complex(GO:0090544)
0.1 1.1 GO:0005915 zonula adherens(GO:0005915)
0.1 0.5 GO:0032280 symmetric synapse(GO:0032280)
0.1 7.6 GO:0005871 kinesin complex(GO:0005871)
0.1 1.6 GO:1990635 proximal dendrite(GO:1990635)
0.1 1.8 GO:0032039 integrator complex(GO:0032039)
0.1 2.5 GO:0000242 pericentriolar material(GO:0000242)
0.1 1.2 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 1.6 GO:0005865 striated muscle thin filament(GO:0005865)
0.1 0.2 GO:1902636 kinociliary basal body(GO:1902636)
0.1 1.7 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 2.8 GO:0035371 microtubule plus-end(GO:0035371)
0.1 0.8 GO:0001940 male pronucleus(GO:0001940)
0.1 2.2 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.3 GO:0098855 HCN channel complex(GO:0098855)
0.1 0.4 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.1 0.7 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.1 1.9 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 1.3 GO:0045120 pronucleus(GO:0045120)
0.1 0.5 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 1.2 GO:0097539 ciliary transition fiber(GO:0097539)
0.1 0.9 GO:0030991 intraciliary transport particle A(GO:0030991)
0.1 0.8 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.1 0.5 GO:0097513 myosin II filament(GO:0097513)
0.1 1.3 GO:0097542 ciliary tip(GO:0097542)
0.1 0.9 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 0.9 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 0.7 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 0.5 GO:0016580 Sin3 complex(GO:0016580)
0.1 0.5 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 0.5 GO:0005955 calcineurin complex(GO:0005955)
0.1 1.1 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.1 0.9 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 0.8 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 0.5 GO:0044232 organelle membrane contact site(GO:0044232)
0.1 0.9 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.1 1.6 GO:0000421 autophagosome membrane(GO:0000421)
0.1 0.5 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.1 0.3 GO:0097651 phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.1 0.7 GO:0030478 actin cap(GO:0030478)
0.1 3.8 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 0.4 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 0.4 GO:0030314 junctional membrane complex(GO:0030314)
0.1 0.8 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.1 0.5 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 0.3 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 2.2 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 1.9 GO:0043034 costamere(GO:0043034)
0.1 4.3 GO:0005902 microvillus(GO:0005902)
0.1 0.9 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.1 0.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 7.3 GO:0000776 kinetochore(GO:0000776)
0.1 7.0 GO:0005923 bicellular tight junction(GO:0005923)
0.1 0.6 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 3.8 GO:0005643 nuclear pore(GO:0005643)
0.1 4.3 GO:0005814 centriole(GO:0005814)
0.1 1.7 GO:0032420 stereocilium(GO:0032420)
0.1 0.6 GO:0010369 chromocenter(GO:0010369)
0.1 1.0 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.9 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.3 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.3 GO:0051233 spindle midzone(GO:0051233)
0.0 1.3 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.2 GO:0070820 tertiary granule(GO:0070820)
0.0 5.5 GO:0032993 protein-DNA complex(GO:0032993)
0.0 1.2 GO:0036126 sperm flagellum(GO:0036126)
0.0 0.2 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.5 GO:0034451 centriolar satellite(GO:0034451)
0.0 1.2 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.4 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.5 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 1.4 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 12.1 GO:0005813 centrosome(GO:0005813)
0.0 1.8 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 3.9 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.9 GO:0001772 immunological synapse(GO:0001772)
0.0 0.1 GO:0043293 apoptosome(GO:0043293)
0.0 2.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.5 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.7 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 3.3 GO:0034399 nuclear periphery(GO:0034399)
0.0 3.1 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.3 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 3.3 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 0.1 GO:0008537 proteasome activator complex(GO:0008537)
0.0 1.0 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.5 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 0.1 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.0 0.1 GO:0002139 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141)
0.0 1.7 GO:0035770 ribonucleoprotein granule(GO:0035770)
0.0 0.2 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.2 GO:0000145 exocyst(GO:0000145)
0.0 1.1 GO:0030532 small nuclear ribonucleoprotein complex(GO:0030532)
0.0 0.9 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 0.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.1 GO:0033503 HULC complex(GO:0033503)
0.0 2.2 GO:0030027 lamellipodium(GO:0030027)
0.0 0.5 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.7 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 10.6 GO:0005730 nucleolus(GO:0005730)
0.0 3.0 GO:0016607 nuclear speck(GO:0016607)
0.0 0.2 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 0.2 GO:1990391 DNA repair complex(GO:1990391)
0.0 0.2 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.0 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.2 GO:0000795 synaptonemal complex(GO:0000795)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 6.2 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
1.1 5.7 GO:0043515 kinetochore binding(GO:0043515)
1.0 4.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
1.0 4.8 GO:0042289 MHC class II protein binding(GO:0042289)
0.9 2.6 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.8 4.1 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.8 2.4 GO:0019966 interleukin-1 binding(GO:0019966)
0.8 4.7 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.7 2.9 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.7 3.3 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.7 2.6 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.6 3.9 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.6 3.8 GO:0035184 histone threonine kinase activity(GO:0035184)
0.6 4.3 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.6 1.7 GO:0047710 bis(5'-adenosyl)-triphosphatase activity(GO:0047710)
0.6 1.7 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.5 2.5 GO:0000405 bubble DNA binding(GO:0000405)
0.5 2.5 GO:0032027 myosin light chain binding(GO:0032027)
0.5 2.4 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.5 2.3 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.5 16.2 GO:0005112 Notch binding(GO:0005112)
0.4 2.2 GO:0004594 pantothenate kinase activity(GO:0004594)
0.4 1.3 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.4 1.3 GO:0001129 RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132)
0.4 2.6 GO:0017040 ceramidase activity(GO:0017040)
0.4 4.3 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.4 1.2 GO:0034190 apolipoprotein receptor binding(GO:0034190)
0.4 2.3 GO:0004984 olfactory receptor activity(GO:0004984)
0.4 4.2 GO:0048185 activin binding(GO:0048185)
0.4 7.8 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.4 2.9 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.4 1.1 GO:0035939 microsatellite binding(GO:0035939)
0.3 2.4 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.3 1.7 GO:0004359 glutaminase activity(GO:0004359)
0.3 1.0 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.3 4.6 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0033764)
0.3 1.6 GO:0030620 U2 snRNA binding(GO:0030620)
0.3 1.6 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.3 3.1 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.3 8.2 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.3 0.9 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.3 1.5 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.3 6.5 GO:0070410 co-SMAD binding(GO:0070410)
0.3 1.7 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.3 2.3 GO:0048495 Roundabout binding(GO:0048495)
0.3 0.8 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.3 0.8 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.3 0.8 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.3 2.2 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.3 0.8 GO:0005436 sodium:phosphate symporter activity(GO:0005436) sodium:inorganic phosphate symporter activity(GO:0015319)
0.3 1.6 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.3 1.3 GO:0004849 uridine kinase activity(GO:0004849)
0.3 2.3 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.3 1.6 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.3 1.8 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.2 9.5 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.2 3.9 GO:0051010 microtubule plus-end binding(GO:0051010)
0.2 1.0 GO:0034618 arginine binding(GO:0034618)
0.2 2.6 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.2 0.7 GO:0071207 histone pre-mRNA stem-loop binding(GO:0071207)
0.2 0.7 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.2 10.1 GO:0008536 Ran GTPase binding(GO:0008536)
0.2 1.3 GO:0008494 translation activator activity(GO:0008494)
0.2 1.3 GO:0097016 L27 domain binding(GO:0097016)
0.2 0.6 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.2 1.2 GO:0043237 laminin-1 binding(GO:0043237)
0.2 1.2 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.2 1.0 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.2 1.8 GO:0070700 BMP receptor binding(GO:0070700)
0.2 0.6 GO:0051379 epinephrine binding(GO:0051379)
0.2 1.8 GO:0042301 phosphate ion binding(GO:0042301)
0.2 1.6 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.2 9.2 GO:0070888 E-box binding(GO:0070888)
0.2 0.8 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.2 0.9 GO:1904288 BAT3 complex binding(GO:1904288)
0.2 1.5 GO:0005523 tropomyosin binding(GO:0005523)
0.2 1.3 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.2 0.5 GO:0000700 mismatch base pair DNA N-glycosylase activity(GO:0000700)
0.2 2.0 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.2 2.9 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.2 2.3 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.2 3.3 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.2 1.0 GO:0023029 MHC class Ib protein binding(GO:0023029)
0.2 1.7 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.2 1.0 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.2 2.4 GO:0017154 semaphorin receptor activity(GO:0017154)
0.2 2.0 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.2 2.7 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.2 1.3 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.2 6.4 GO:0005109 frizzled binding(GO:0005109)
0.2 6.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.2 0.5 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.2 1.1 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.2 1.4 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.2 0.8 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.1 2.9 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 0.6 GO:1990254 keratin filament binding(GO:1990254)
0.1 1.8 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 0.6 GO:0070976 calcium-independent protein kinase C activity(GO:0004699) TIR domain binding(GO:0070976)
0.1 2.8 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.1 4.9 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 1.4 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 1.4 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.1 0.8 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.1 1.5 GO:0035198 miRNA binding(GO:0035198)
0.1 1.1 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.1 1.1 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1 1.7 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 0.8 GO:0034046 poly(G) binding(GO:0034046)
0.1 1.7 GO:0005522 profilin binding(GO:0005522)
0.1 0.4 GO:0008527 taste receptor activity(GO:0008527)
0.1 0.8 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 0.8 GO:0001515 opioid peptide activity(GO:0001515)
0.1 1.3 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.1 1.0 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.1 0.4 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.1 2.4 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 0.6 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.1 0.8 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 2.0 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1 1.7 GO:0017166 vinculin binding(GO:0017166)
0.1 0.5 GO:0036033 mediator complex binding(GO:0036033)
0.1 1.8 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 2.1 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 0.3 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.1 2.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 0.8 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 0.1 GO:0015464 acetylcholine receptor activity(GO:0015464)
0.1 0.3 GO:0000402 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
0.1 0.9 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.1 1.0 GO:0008227 G-protein coupled amine receptor activity(GO:0008227)
0.1 2.2 GO:0017160 Ral GTPase binding(GO:0017160)
0.1 1.2 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.1 1.0 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.1 0.6 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.1 0.5 GO:0008172 S-methyltransferase activity(GO:0008172)
0.1 0.3 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.1 0.3 GO:0001729 ceramide kinase activity(GO:0001729)
0.1 0.5 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 1.9 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 1.5 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 10.4 GO:0003774 motor activity(GO:0003774)
0.1 0.6 GO:0031419 cobalamin binding(GO:0031419)
0.1 10.8 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 0.7 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 1.0 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 1.4 GO:0035613 RNA stem-loop binding(GO:0035613)
0.1 0.5 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 2.6 GO:0017091 AU-rich element binding(GO:0017091)
0.1 4.8 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.1 0.2 GO:0004630 phospholipase D activity(GO:0004630)
0.1 0.3 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.1 0.4 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.7 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 0.2 GO:0016015 morphogen activity(GO:0016015)
0.1 0.5 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 0.6 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 1.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 1.5 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 0.1 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.1 0.2 GO:0009881 photoreceptor activity(GO:0009881)
0.1 0.5 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 0.5 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 1.4 GO:0048365 Rac GTPase binding(GO:0048365)
0.1 1.4 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.1 0.7 GO:0051787 misfolded protein binding(GO:0051787)
0.1 1.1 GO:0070628 proteasome binding(GO:0070628)
0.1 0.9 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 1.6 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 0.4 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.1 0.3 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.1 0.3 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.1 0.6 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.6 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1 2.6 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 1.3 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 1.7 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 18.6 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.1 0.4 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 0.2 GO:0016979 lipoate-protein ligase activity(GO:0016979)
0.1 0.5 GO:0051011 microtubule minus-end binding(GO:0051011)
0.1 1.2 GO:0031489 myosin V binding(GO:0031489)
0.1 0.3 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.1 0.2 GO:0098809 nitrite reductase activity(GO:0098809)
0.1 8.4 GO:0000982 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982)
0.1 6.5 GO:0001047 core promoter binding(GO:0001047)
0.1 1.3 GO:0042171 lysophosphatidic acid acyltransferase activity(GO:0042171)
0.1 0.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.2 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.1 0.7 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.1 0.5 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.1 0.2 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.1 1.2 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 1.5 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 0.6 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.9 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 3.0 GO:0035064 methylated histone binding(GO:0035064)
0.0 2.4 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.9 GO:0043274 phospholipase binding(GO:0043274)
0.0 4.2 GO:0030414 peptidase inhibitor activity(GO:0030414)
0.0 0.1 GO:0030172 troponin C binding(GO:0030172)
0.0 1.3 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.9 GO:0070064 proline-rich region binding(GO:0070064)
0.0 1.9 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.3 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.2 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 1.1 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 1.4 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.5 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 5.0 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.5 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 1.0 GO:0043175 RNA polymerase core enzyme binding(GO:0043175)
0.0 0.8 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.0 0.4 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 0.5 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.1 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.7 GO:0043236 laminin binding(GO:0043236)
0.0 0.5 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.1 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 1.8 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.3 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.6 GO:0052866 phosphatidylinositol phosphate phosphatase activity(GO:0052866)
0.0 0.3 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.1 GO:0004127 cytidylate kinase activity(GO:0004127) uridylate kinase activity(GO:0009041)
0.0 0.2 GO:0015377 cation:chloride symporter activity(GO:0015377)
0.0 1.0 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 1.0 GO:0015631 tubulin binding(GO:0015631)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 1.5 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.4 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 2.7 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.1 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.3 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.6 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.2 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 0.2 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.2 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.0 0.1 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.2 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.2 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.1 GO:2001069 glycogen binding(GO:2001069)
0.0 0.4 GO:0008483 transaminase activity(GO:0008483)
0.0 0.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 1.1 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 1.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.8 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.1 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.0 0.1 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0 0.1 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.1 GO:0061135 endopeptidase regulator activity(GO:0061135)
0.0 0.2 GO:0050308 sugar-phosphatase activity(GO:0050308)
0.0 0.1 GO:0032564 dATP binding(GO:0032564)
0.0 0.1 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.2 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.1 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 0.1 GO:0015116 sulfate transmembrane transporter activity(GO:0015116)
0.0 0.1 GO:0050733 RS domain binding(GO:0050733)
0.0 0.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.2 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.4 GO:0002039 p53 binding(GO:0002039)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 10.7 PID_TCR_JNK_PATHWAY JNK signaling in the CD4+ TCR pathway
0.5 1.1 PID_FAS_PATHWAY FAS (CD95) signaling pathway
0.5 2.1 PID_ALK1_PATHWAY ALK1 signaling events
0.4 16.9 PID_AURORA_B_PATHWAY Aurora B signaling
0.3 12.4 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.3 3.0 PID_ALK2_PATHWAY ALK2 signaling events
0.2 11.1 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.2 1.5 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.2 3.1 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.2 0.9 ST_IL_13_PATHWAY Interleukin 13 (IL-13) Pathway
0.2 16.9 PID_NOTCH_PATHWAY Notch signaling pathway
0.2 0.5 PID_RANBP2_PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 0.6 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 5.0 PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 1.1 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.1 2.3 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.1 0.4 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.1 3.8 PID_BARD1_PATHWAY BARD1 signaling events
0.1 4.4 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 3.5 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 4.2 NABA_COLLAGENS Genes encoding collagen proteins
0.1 2.7 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 1.8 PID_PS1_PATHWAY Presenilin action in Notch and Wnt signaling
0.1 1.9 PID_FAK_PATHWAY Signaling events mediated by focal adhesion kinase
0.1 0.4 PID_INTEGRIN_CS_PATHWAY Integrin family cell surface interactions
0.1 3.5 PID_ECADHERIN_NASCENT_AJ_PATHWAY E-cadherin signaling in the nascent adherens junction
0.1 2.1 PID_PI3K_PLC_TRK_PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.1 3.3 PID_ERBB4_PATHWAY ErbB4 signaling events
0.1 0.9 PID_CONE_PATHWAY Visual signal transduction: Cones
0.1 1.7 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 2.0 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 0.7 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.1 1.3 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.1 2.5 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity
0.1 1.3 PID_AURORA_A_PATHWAY Aurora A signaling
0.1 1.6 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 1.5 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.1 3.2 PID_E2F_PATHWAY E2F transcription factor network
0.0 0.5 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.5 PID_AP1_PATHWAY AP-1 transcription factor network
0.0 0.9 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.0 0.7 SA_B_CELL_RECEPTOR_COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 2.2 PID_HDAC_CLASSII_PATHWAY Signaling events mediated by HDAC Class II
0.0 2.0 PID_PLK1_PATHWAY PLK1 signaling events
0.0 0.5 ST_G_ALPHA_I_PATHWAY G alpha i Pathway
0.0 1.7 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events
0.0 0.6 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.6 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 1.3 PID_CMYB_PATHWAY C-MYB transcription factor network
0.0 0.5 PID_FGF_PATHWAY FGF signaling pathway
0.0 0.7 PID_FANCONI_PATHWAY Fanconi anemia pathway
0.0 1.4 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.9 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 1.5 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.5 PID_RB_1PATHWAY Regulation of retinoblastoma protein
0.0 0.1 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events
0.0 0.2 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.0 0.3 PID_ARF6_PATHWAY Arf6 signaling events
0.0 0.2 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.0 0.2 PID_THROMBIN_PAR1_PATHWAY PAR1-mediated thrombin signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 0.7 REACTOME_SIGNALING_BY_FGFR_IN_DISEASE Genes involved in Signaling by FGFR in disease
0.5 2.2 REACTOME_ETHANOL_OXIDATION Genes involved in Ethanol oxidation
0.4 3.1 REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.3 1.7 REACTOME_ENOS_ACTIVATION_AND_REGULATION Genes involved in eNOS activation and regulation
0.3 1.6 REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.3 2.1 REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.3 4.2 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.2 7.3 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.2 0.2 REACTOME_SIGNALING_BY_NOTCH3 Genes involved in Signaling by NOTCH3
0.2 7.1 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.2 5.0 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.2 5.0 REACTOME_KINESINS Genes involved in Kinesins
0.2 4.8 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.2 2.2 REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.2 8.3 REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS Genes involved in Trafficking of AMPA receptors
0.2 2.7 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_LATE_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.2 3.5 REACTOME_INCRETIN_SYNTHESIS_SECRETION_AND_INACTIVATION Genes involved in Incretin Synthesis, Secretion, and Inactivation
0.2 17.6 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.2 8.2 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.2 4.3 REACTOME_TRAF6_MEDIATED_NFKB_ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.2 2.2 REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.2 2.8 REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.2 2.9 REACTOME_DESTABILIZATION_OF_MRNA_BY_TRISTETRAPROLIN_TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.2 1.5 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 3.2 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1
0.1 3.0 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 5.8 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.1 3.6 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 1.3 REACTOME_CELL_SURFACE_INTERACTIONS_AT_THE_VASCULAR_WALL Genes involved in Cell surface interactions at the vascular wall
0.1 1.1 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 1.6 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 1.2 REACTOME_CALNEXIN_CALRETICULIN_CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 1.1 REACTOME_UNBLOCKING_OF_NMDA_RECEPTOR_GLUTAMATE_BINDING_AND_ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.1 3.2 REACTOME_DOUBLE_STRAND_BREAK_REPAIR Genes involved in Double-Strand Break Repair
0.1 1.7 REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 1.1 REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM Genes involved in Abacavir transport and metabolism
0.1 1.2 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.1 3.8 REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 0.9 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.1 1.5 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL
0.1 2.9 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 0.3 REACTOME_DSCAM_INTERACTIONS Genes involved in DSCAM interactions
0.1 0.5 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 0.6 REACTOME_REGULATION_OF_KIT_SIGNALING Genes involved in Regulation of KIT signaling
0.1 1.5 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 4.0 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.1 2.2 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.1 1.6 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 2.4 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.1 1.2 REACTOME_FORMATION_OF_INCISION_COMPLEX_IN_GG_NER Genes involved in Formation of incision complex in GG-NER
0.1 3.6 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.1 0.5 REACTOME_REGULATION_OF_IFNG_SIGNALING Genes involved in Regulation of IFNG signaling
0.1 1.8 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.1 1.2 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.1 1.5 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.1 0.9 REACTOME_STEROID_HORMONES Genes involved in Steroid hormones
0.1 0.9 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 0.8 REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1 0.8 REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES Genes involved in Generation of second messenger molecules
0.1 3.0 REACTOME_SIGNALING_BY_NOTCH1 Genes involved in Signaling by NOTCH1
0.1 0.5 REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1 0.7 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 1.8 REACTOME_CELL_CELL_JUNCTION_ORGANIZATION Genes involved in Cell-cell junction organization
0.1 0.5 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 0.7 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 0.2 REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING Genes involved in Spry regulation of FGF signaling
0.1 1.8 REACTOME_POST_TRANSLATIONAL_MODIFICATION_SYNTHESIS_OF_GPI_ANCHORED_PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.1 2.3 REACTOME_CLEAVAGE_OF_GROWING_TRANSCRIPT_IN_THE_TERMINATION_REGION_ Genes involved in Cleavage of Growing Transcript in the Termination Region
0.0 3.7 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.0 1.7 REACTOME_GLYCOSPHINGOLIPID_METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 1.2 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 1.1 REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 1.1 REACTOME_TRANSPORT_OF_RIBONUCLEOPROTEINS_INTO_THE_HOST_NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.4 REACTOME_GLUCOSE_TRANSPORT Genes involved in Glucose transport
0.0 0.6 REACTOME_SOS_MEDIATED_SIGNALLING Genes involved in SOS-mediated signalling
0.0 4.2 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.8 REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.5 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.7 REACTOME_FORMATION_OF_TRANSCRIPTION_COUPLED_NER_TC_NER_REPAIR_COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0 0.5 REACTOME_ACYL_CHAIN_REMODELLING_OF_PC Genes involved in Acyl chain remodelling of PC
0.0 1.5 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.3 REACTOME_G_ALPHA1213_SIGNALLING_EVENTS Genes involved in G alpha (12/13) signalling events
0.0 0.4 REACTOME_TRANSCRIPTIONAL_ACTIVITY_OF_SMAD2_SMAD3_SMAD4_HETEROTRIMER Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
0.0 1.5 REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 1.1 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.0 0.9 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.0 6.7 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.2 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.1 REACTOME_INHIBITION_OF_REPLICATION_INITIATION_OF_DAMAGED_DNA_BY_RB1_E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.4 REACTOME_ERK_MAPK_TARGETS Genes involved in ERK/MAPK targets
0.0 1.3 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.2 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_GLUCAGON_LIKE_PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 0.8 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.2 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.4 REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.6 REACTOME_IRON_UPTAKE_AND_TRANSPORT Genes involved in Iron uptake and transport
0.0 0.9 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.4 REACTOME_TRANSPORT_TO_THE_GOLGI_AND_SUBSEQUENT_MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.1 REACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins