Motif ID: Nkx6-1_Evx1_Hesx1

Z-value: 0.856

Transcription factors associated with Nkx6-1_Evx1_Hesx1:

Gene SymbolEntrez IDGene Name
Evx1 ENSMUSG00000005503.8 Evx1
Hesx1 ENSMUSG00000040726.8 Hesx1
Nkx6-1 ENSMUSG00000035187.8 Nkx6-1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nkx6-1mm10_v2_chr5_-_101665195_1016652260.181.1e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Nkx6-1_Evx1_Hesx1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_+_25773985 19.460 ENSMUST00000125667.1
Myo10
myosin X
chr5_-_62766153 14.916 ENSMUST00000076623.4
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr14_-_118052235 13.594 ENSMUST00000022725.2
Dct
dopachrome tautomerase
chr3_-_49757257 12.039 ENSMUST00000035931.7
Pcdh18
protocadherin 18
chr4_+_8690399 11.462 ENSMUST00000127476.1
Chd7
chromodomain helicase DNA binding protein 7
chr2_-_79456750 11.439 ENSMUST00000041099.4
Neurod1
neurogenic differentiation 1
chr9_+_118478182 10.608 ENSMUST00000111763.1
Eomes
eomesodermin homolog (Xenopus laevis)
chr9_+_118478344 10.095 ENSMUST00000035020.8
Eomes
eomesodermin homolog (Xenopus laevis)
chr2_+_20737306 9.829 ENSMUST00000114606.1
ENSMUST00000114608.1
Etl4

enhancer trap locus 4

chr5_-_84417359 9.397 ENSMUST00000113401.1
Epha5
Eph receptor A5
chrM_+_9870 8.976 ENSMUST00000084013.1
mt-Nd4l
mitochondrially encoded NADH dehydrogenase 4L
chrX_+_56454871 8.885 ENSMUST00000039374.2
ENSMUST00000101553.2
Ddx26b

DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B

chrM_+_11734 8.710 ENSMUST00000082418.1
mt-Nd5
mitochondrially encoded NADH dehydrogenase 5
chr2_+_116067213 8.559 ENSMUST00000152412.1
G630016G05Rik
RIKEN cDNA G630016G05 gene
chr13_+_44121167 8.518 ENSMUST00000163056.1
ENSMUST00000159595.1
Gm5083

predicted gene 5083

chr1_-_24612700 8.388 ENSMUST00000088336.1
Gm10222
predicted gene 10222
chr14_-_100149764 7.853 ENSMUST00000097079.4
Klf12
Kruppel-like factor 12
chr1_-_172027269 7.849 ENSMUST00000027837.6
ENSMUST00000111264.1
Vangl2

vang-like 2 (van gogh, Drosophila)

chr2_-_116067391 7.511 ENSMUST00000140185.1
2700033N17Rik
RIKEN cDNA 2700033N17 gene
chrM_+_10167 6.617 ENSMUST00000082414.1
mt-Nd4
mitochondrially encoded NADH dehydrogenase 4
chr7_+_29071597 6.358 ENSMUST00000180926.1
Gm26604
predicted gene, 26604
chr16_+_33684538 6.266 ENSMUST00000126532.1
Heg1
HEG homolog 1 (zebrafish)
chr1_+_139454747 6.188 ENSMUST00000053364.8
ENSMUST00000097554.3
Aspm

asp (abnormal spindle)-like, microcephaly associated (Drosophila)

chr1_-_190170671 6.116 ENSMUST00000175916.1
Prox1
prospero-related homeobox 1
chr6_-_101377897 6.036 ENSMUST00000075994.6
Pdzrn3
PDZ domain containing RING finger 3
chr1_-_172027251 5.743 ENSMUST00000138714.1
Vangl2
vang-like 2 (van gogh, Drosophila)
chr4_-_109665249 5.410 ENSMUST00000063531.4
Cdkn2c
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
chr8_-_61902669 5.345 ENSMUST00000121785.1
ENSMUST00000034057.7
Palld

palladin, cytoskeletal associated protein

chr17_-_35697971 5.118 ENSMUST00000146472.1
Ddr1
discoidin domain receptor family, member 1
chr9_+_65890237 4.987 ENSMUST00000045802.6
2810417H13Rik
RIKEN cDNA 2810417H13 gene
chr5_-_53707532 4.902 ENSMUST00000031093.3
Cckar
cholecystokinin A receptor
chrM_+_7759 4.861 ENSMUST00000082407.1
ENSMUST00000082408.1
mt-Atp8
mt-Atp6
mitochondrially encoded ATP synthase 8
mitochondrially encoded ATP synthase 6
chr4_-_155056784 4.674 ENSMUST00000131173.2
Plch2
phospholipase C, eta 2
chr10_+_18469958 4.667 ENSMUST00000162891.1
ENSMUST00000100054.3
Nhsl1

NHS-like 1

chr13_-_56252163 4.556 ENSMUST00000058475.4
Neurog1
neurogenin 1
chr11_-_98053415 4.532 ENSMUST00000017544.2
Stac2
SH3 and cysteine rich domain 2
chr16_-_63864114 4.495 ENSMUST00000064405.6
Epha3
Eph receptor A3
chr14_+_73237891 4.427 ENSMUST00000044405.6
Lpar6
lysophosphatidic acid receptor 6
chr5_-_99252839 4.330 ENSMUST00000168092.1
ENSMUST00000031276.8
Rasgef1b

RasGEF domain family, member 1B

chr15_+_55307743 4.321 ENSMUST00000023053.5
ENSMUST00000110221.2
ENSMUST00000110217.3
Col14a1


collagen, type XIV, alpha 1


chr9_+_96258697 4.312 ENSMUST00000179416.1
Tfdp2
transcription factor Dp 2
chr8_+_23411490 4.254 ENSMUST00000033952.7
Sfrp1
secreted frizzled-related protein 1
chr2_+_84734050 4.232 ENSMUST00000090729.2
Ypel4
yippee-like 4 (Drosophila)
chr3_-_88410295 4.227 ENSMUST00000056370.7
Pmf1
polyamine-modulated factor 1
chr13_+_44729535 4.131 ENSMUST00000174068.1
Jarid2
jumonji, AT rich interactive domain 2
chr6_-_57535422 4.011 ENSMUST00000042766.3
Ppm1k
protein phosphatase 1K (PP2C domain containing)
chr4_+_109978004 3.951 ENSMUST00000061187.3
Dmrta2
doublesex and mab-3 related transcription factor like family A2
chr5_+_138187485 3.880 ENSMUST00000110934.2
Cnpy4
canopy 4 homolog (zebrafish)
chr7_+_103550368 3.851 ENSMUST00000106888.1
Olfr613
olfactory receptor 613
chr17_+_17402672 3.847 ENSMUST00000115576.2
Lix1
limb expression 1 homolog (chicken)
chr7_+_123123870 3.801 ENSMUST00000094053.5
Tnrc6a
trinucleotide repeat containing 6a
chr1_-_155417394 3.516 ENSMUST00000111775.1
ENSMUST00000111774.1
Xpr1

xenotropic and polytropic retrovirus receptor 1

chr7_+_67647405 3.507 ENSMUST00000032774.8
ENSMUST00000107471.1
Ttc23

tetratricopeptide repeat domain 23

chr7_-_73541738 3.408 ENSMUST00000169922.2
Chd2
chromodomain helicase DNA binding protein 2
chr16_+_33684460 3.367 ENSMUST00000152782.1
ENSMUST00000179453.1
Heg1

HEG homolog 1 (zebrafish)

chr18_+_57468478 3.360 ENSMUST00000091892.2
Ctxn3
cortexin 3
chr2_+_125068118 3.343 ENSMUST00000070353.3
Slc24a5
solute carrier family 24, member 5
chr2_+_25372315 3.314 ENSMUST00000028329.6
ENSMUST00000114293.2
ENSMUST00000100323.2
Sapcd2


suppressor APC domain containing 2


chr12_-_55014329 3.305 ENSMUST00000172875.1
Baz1a
bromodomain adjacent to zinc finger domain 1A
chr16_+_42907563 3.275 ENSMUST00000151244.1
ENSMUST00000114694.2
Zbtb20

zinc finger and BTB domain containing 20

chr8_+_45627709 3.268 ENSMUST00000134321.1
ENSMUST00000135336.1
Sorbs2

sorbin and SH3 domain containing 2

chr4_+_97777780 3.261 ENSMUST00000107062.2
ENSMUST00000052018.5
ENSMUST00000107057.1
Nfia


nuclear factor I/A


chr9_-_96719549 3.155 ENSMUST00000128269.1
Zbtb38
zinc finger and BTB domain containing 38
chr8_-_84662841 3.138 ENSMUST00000060427.4
Ier2
immediate early response 2
chr15_+_18818895 3.028 ENSMUST00000166873.2
Cdh10
cadherin 10
chrM_+_2743 3.020 ENSMUST00000082392.1
mt-Nd1
mitochondrially encoded NADH dehydrogenase 1
chr6_+_56017489 3.007 ENSMUST00000052827.4
Ppp1r17
protein phosphatase 1, regulatory subunit 17
chr5_-_131616599 2.963 ENSMUST00000161804.1
Auts2
autism susceptibility candidate 2
chrM_+_7005 2.927 ENSMUST00000082405.1
mt-Co2
mitochondrially encoded cytochrome c oxidase II
chr12_-_54986363 2.923 ENSMUST00000173433.1
ENSMUST00000173803.1
Baz1a
Gm20403
bromodomain adjacent to zinc finger domain 1A
predicted gene 20403
chr12_-_111813834 2.916 ENSMUST00000021715.5
Xrcc3
X-ray repair complementing defective repair in Chinese hamster cells 3
chr4_-_97778042 2.911 ENSMUST00000146447.1
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr3_-_66296807 2.909 ENSMUST00000029419.7
Veph1
ventricular zone expressed PH domain-containing 1
chr5_+_64812336 2.901 ENSMUST00000166409.1
Klf3
Kruppel-like factor 3 (basic)
chr8_-_120228221 2.853 ENSMUST00000183235.1
A330074K22Rik
RIKEN cDNA A330074K22 gene
chr9_-_96719404 2.852 ENSMUST00000140121.1
Zbtb38
zinc finger and BTB domain containing 38
chr6_+_34746368 2.845 ENSMUST00000142716.1
Cald1
caldesmon 1
chr2_+_23069210 2.827 ENSMUST00000155602.1
Acbd5
acyl-Coenzyme A binding domain containing 5
chr1_-_163725123 2.738 ENSMUST00000159679.1
Mettl11b
methyltransferase like 11B
chr7_-_37772868 2.733 ENSMUST00000176205.1
Zfp536
zinc finger protein 536
chrM_-_14060 2.730 ENSMUST00000082419.1
mt-Nd6
mitochondrially encoded NADH dehydrogenase 6
chr4_-_45532470 2.691 ENSMUST00000147448.1
Shb
src homology 2 domain-containing transforming protein B
chr5_+_103754560 2.682 ENSMUST00000153165.1
ENSMUST00000031256.5
Aff1

AF4/FMR2 family, member 1

chr3_+_76075583 2.654 ENSMUST00000160261.1
Fstl5
follistatin-like 5
chr7_+_67655414 2.646 ENSMUST00000107470.1
Ttc23
tetratricopeptide repeat domain 23
chr17_-_70853482 2.602 ENSMUST00000118283.1
Tgif1
TGFB-induced factor homeobox 1
chr14_-_12345847 2.586 ENSMUST00000022262.4
Fezf2
Fez family zinc finger 2
chr14_-_47411666 2.572 ENSMUST00000111778.3
Dlgap5
discs, large (Drosophila) homolog-associated protein 5
chr5_-_124095749 2.545 ENSMUST00000031354.4
Abcb9
ATP-binding cassette, sub-family B (MDR/TAP), member 9
chr18_-_39487096 2.544 ENSMUST00000097592.2
ENSMUST00000115571.1
Nr3c1

nuclear receptor subfamily 3, group C, member 1

chr5_+_92809372 2.535 ENSMUST00000113054.2
Shroom3
shroom family member 3
chr15_+_25742314 2.493 ENSMUST00000135981.1
Myo10
myosin X
chr13_-_103764502 2.417 ENSMUST00000074616.5
Srek1
splicing regulatory glutamine/lysine-rich protein 1
chr17_-_29007925 2.399 ENSMUST00000009138.5
ENSMUST00000119274.1
Stk38

serine/threonine kinase 38

chrX_-_74246534 2.374 ENSMUST00000101454.2
ENSMUST00000033699.6
Flna

filamin, alpha

chr2_+_52038005 2.343 ENSMUST00000065927.5
Tnfaip6
tumor necrosis factor alpha induced protein 6
chr11_-_87359011 2.329 ENSMUST00000055438.4
Ppm1e
protein phosphatase 1E (PP2C domain containing)
chr4_-_43499608 2.284 ENSMUST00000136005.1
ENSMUST00000054538.6
Arhgef39

Rho guanine nucleotide exchange factor (GEF) 39

chr8_+_45658731 2.284 ENSMUST00000143820.1
ENSMUST00000132139.1
Sorbs2

sorbin and SH3 domain containing 2

chr2_+_69897255 2.279 ENSMUST00000131553.1
Ubr3
ubiquitin protein ligase E3 component n-recognin 3
chr8_+_45658666 2.278 ENSMUST00000134675.1
ENSMUST00000139869.1
ENSMUST00000126067.1
Sorbs2


sorbin and SH3 domain containing 2


chr13_-_85127514 2.226 ENSMUST00000179230.1
Gm4076
predicted gene 4076
chr6_-_54593139 2.218 ENSMUST00000046520.6
Fkbp14
FK506 binding protein 14
chr8_-_31918203 2.174 ENSMUST00000073884.4
Nrg1
neuregulin 1
chr2_+_119047129 2.163 ENSMUST00000153300.1
ENSMUST00000028799.5
Casc5

cancer susceptibility candidate 5

chr19_+_23723279 2.160 ENSMUST00000067077.1
Gm9938
predicted gene 9938
chr4_-_82850721 2.157 ENSMUST00000139401.1
Zdhhc21
zinc finger, DHHC domain containing 21
chr2_+_61593077 2.156 ENSMUST00000112495.1
ENSMUST00000112501.2
Tank

TRAF family member-associated Nf-kappa B activator

chr6_-_108185552 2.153 ENSMUST00000167338.1
ENSMUST00000172188.1
ENSMUST00000032191.9
Sumf1


sulfatase modifying factor 1


chr3_+_127553462 2.152 ENSMUST00000043108.4
4930422G04Rik
RIKEN cDNA 4930422G04 gene
chr14_+_54259227 2.145 ENSMUST00000041197.7
Abhd4
abhydrolase domain containing 4
chr9_+_13621646 2.135 ENSMUST00000034401.8
Maml2
mastermind like 2 (Drosophila)
chrX_-_102157065 2.128 ENSMUST00000056904.2
Ercc6l
excision repair cross-complementing rodent repair deficiency complementation group 6 like
chr4_-_24430838 2.125 ENSMUST00000183964.1
RP23-35K5.2
RP23-35K5.2
chr3_+_32436376 2.106 ENSMUST00000108242.1
Pik3ca
phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
chr4_+_62583568 2.093 ENSMUST00000098031.3
Rgs3
regulator of G-protein signaling 3
chr10_+_58394381 2.071 ENSMUST00000105468.1
Lims1
LIM and senescent cell antigen-like domains 1
chr7_+_64185459 2.065 ENSMUST00000177102.2
ENSMUST00000107519.1
ENSMUST00000137650.1
ENSMUST00000032737.5
ENSMUST00000107515.1
ENSMUST00000144996.1
Trpm1





transient receptor potential cation channel, subfamily M, member 1





chrX_-_60893430 2.034 ENSMUST00000135107.2
Sox3
SRY-box containing gene 3
chr10_+_127420867 1.999 ENSMUST00000064793.6
R3hdm2
R3H domain containing 2
chr4_+_80910646 1.968 ENSMUST00000055922.3
Lurap1l
leucine rich adaptor protein 1-like
chr10_-_117148474 1.951 ENSMUST00000020381.3
Frs2
fibroblast growth factor receptor substrate 2
chr5_-_62765618 1.949 ENSMUST00000159470.1
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr8_-_26119125 1.944 ENSMUST00000037182.7
Hook3
hook homolog 3 (Drosophila)
chrM_+_3906 1.936 ENSMUST00000082396.1
mt-Nd2
mitochondrially encoded NADH dehydrogenase 2
chr11_+_75532099 1.933 ENSMUST00000169547.2
Slc43a2
solute carrier family 43, member 2
chr10_+_127421208 1.921 ENSMUST00000168780.1
R3hdm2
R3H domain containing 2
chr3_+_32436151 1.877 ENSMUST00000029201.7
Pik3ca
phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
chr18_+_82914632 1.868 ENSMUST00000071233.6
Zfp516
zinc finger protein 516
chr9_-_15357692 1.859 ENSMUST00000098979.3
ENSMUST00000161132.1
5830418K08Rik

RIKEN cDNA 5830418K08 gene

chr9_-_50739365 1.855 ENSMUST00000117093.1
ENSMUST00000121634.1
Dixdc1

DIX domain containing 1

chr4_-_110292719 1.841 ENSMUST00000106601.1
Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr8_-_67818284 1.834 ENSMUST00000120071.1
Psd3
pleckstrin and Sec7 domain containing 3
chr2_+_144527718 1.826 ENSMUST00000028914.2
ENSMUST00000110017.2
Polr3f

polymerase (RNA) III (DNA directed) polypeptide F

chr9_+_89199319 1.814 ENSMUST00000138109.1
Mthfs
5, 10-methenyltetrahydrofolate synthetase
chr3_+_94413244 1.806 ENSMUST00000166032.1
ENSMUST00000045245.5
Tdrkh

tudor and KH domain containing protein

chr7_+_126776939 1.784 ENSMUST00000038614.5
ENSMUST00000170882.1
ENSMUST00000106359.1
ENSMUST00000106357.1
ENSMUST00000145762.1
ENSMUST00000132643.1
ENSMUST00000106356.1
Ypel3






yippee-like 3 (Drosophila)






chr2_+_69897220 1.778 ENSMUST00000055758.9
ENSMUST00000112251.2
Ubr3

ubiquitin protein ligase E3 component n-recognin 3

chr2_+_61593125 1.772 ENSMUST00000112494.1
Tank
TRAF family member-associated Nf-kappa B activator
chr6_+_134929118 1.764 ENSMUST00000185152.1
ENSMUST00000184504.1
RP23-45G16.5

RP23-45G16.5

chr10_+_58394361 1.760 ENSMUST00000020077.4
Lims1
LIM and senescent cell antigen-like domains 1
chr17_+_45734506 1.756 ENSMUST00000180558.1
F630040K05Rik
RIKEN cDNA F630040K05 gene
chr5_+_13398688 1.740 ENSMUST00000125629.1
Sema3a
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr6_+_37870786 1.730 ENSMUST00000120428.1
ENSMUST00000031859.7
Trim24

tripartite motif-containing 24

chr9_+_52047150 1.730 ENSMUST00000163153.1
Rdx
radixin
chr1_-_155417283 1.729 ENSMUST00000027741.5
Xpr1
xenotropic and polytropic retrovirus receptor 1
chr16_+_43247278 1.705 ENSMUST00000114691.1
ENSMUST00000079441.6
Zbtb20

zinc finger and BTB domain containing 20

chr13_-_89742244 1.700 ENSMUST00000109543.2
ENSMUST00000159337.1
ENSMUST00000159910.1
ENSMUST00000109544.2
Vcan



versican



chr8_-_67974567 1.694 ENSMUST00000098696.3
ENSMUST00000038959.9
ENSMUST00000093469.4
Psd3


pleckstrin and Sec7 domain containing 3


chr10_+_26772477 1.692 ENSMUST00000039557.7
Arhgap18
Rho GTPase activating protein 18
chr14_+_12189943 1.687 ENSMUST00000119888.1
Ptprg
protein tyrosine phosphatase, receptor type, G
chr6_+_15196949 1.686 ENSMUST00000151301.1
ENSMUST00000131414.1
ENSMUST00000140557.1
ENSMUST00000115469.1
Foxp2



forkhead box P2



chr5_-_88675190 1.684 ENSMUST00000133532.1
ENSMUST00000150438.1
Grsf1

G-rich RNA sequence binding factor 1

chr5_+_34999046 1.675 ENSMUST00000114281.1
Rgs12
regulator of G-protein signaling 12
chr3_-_19264959 1.654 ENSMUST00000121951.1
Pde7a
phosphodiesterase 7A
chr10_+_127421124 1.640 ENSMUST00000170336.1
R3hdm2
R3H domain containing 2
chr5_+_34999111 1.634 ENSMUST00000114283.1
Rgs12
regulator of G-protein signaling 12
chrX_-_60403947 1.633 ENSMUST00000033480.6
ENSMUST00000101527.2
Atp11c

ATPase, class VI, type 11C

chr3_+_94398517 1.630 ENSMUST00000050975.3
Lingo4
leucine rich repeat and Ig domain containing 4
chrM_+_14138 1.626 ENSMUST00000082421.1
mt-Cytb
mitochondrially encoded cytochrome b
chr14_+_79515618 1.617 ENSMUST00000110835.1
Elf1
E74-like factor 1
chr7_+_66365905 1.617 ENSMUST00000107486.1
Gm10974
predicted gene 10974
chr9_+_72274966 1.616 ENSMUST00000183410.1
Zfp280d
zinc finger protein 280D
chr16_-_37384915 1.601 ENSMUST00000114787.1
ENSMUST00000114782.1
ENSMUST00000023526.2
ENSMUST00000114775.1
Stxbp5l



syntaxin binding protein 5-like



chr16_-_16560201 1.601 ENSMUST00000162045.1
ENSMUST00000162124.1
ENSMUST00000161861.1
Fgd4


FYVE, RhoGEF and PH domain containing 4


chr17_+_3532554 1.600 ENSMUST00000168560.1
Cldn20
claudin 20
chr3_-_157925056 1.599 ENSMUST00000118539.1
Cth
cystathionase (cystathionine gamma-lyase)
chr4_+_128993224 1.585 ENSMUST00000030583.6
ENSMUST00000102604.4
Ak2

adenylate kinase 2

chr5_+_34999070 1.578 ENSMUST00000114280.1
Rgs12
regulator of G-protein signaling 12
chr9_-_66514567 1.564 ENSMUST00000056890.8
Fbxl22
F-box and leucine-rich repeat protein 22
chr11_+_94327984 1.552 ENSMUST00000107818.2
ENSMUST00000051221.6
Ankrd40

ankyrin repeat domain 40

chr15_+_31224371 1.522 ENSMUST00000044524.9
Dap
death-associated protein
chr12_+_55598917 1.512 ENSMUST00000051857.3
Insm2
insulinoma-associated 2
chr16_-_37384940 1.483 ENSMUST00000114781.1
ENSMUST00000114780.1
Stxbp5l

syntaxin binding protein 5-like

chr4_-_96553617 1.479 ENSMUST00000030303.5
Cyp2j6
cytochrome P450, family 2, subfamily j, polypeptide 6
chr12_+_71170589 1.451 ENSMUST00000129376.1
2700049A03Rik
RIKEN cDNA 2700049A03 gene
chr2_+_131491764 1.436 ENSMUST00000028806.5
ENSMUST00000110179.2
ENSMUST00000110189.2
ENSMUST00000110182.2
ENSMUST00000110183.2
ENSMUST00000110186.2
ENSMUST00000110188.1
Smox






spermine oxidase






chr4_-_42661893 1.428 ENSMUST00000108006.3
Il11ra2
interleukin 11 receptor, alpha chain 2
chr1_+_194619815 1.419 ENSMUST00000027952.5
Plxna2
plexin A2
chrX_-_53269786 1.409 ENSMUST00000114841.1
ENSMUST00000071023.5
Fam122b

family with sequence similarity 122, member B

chr7_-_80405425 1.399 ENSMUST00000107362.3
ENSMUST00000135306.1
Furin

furin (paired basic amino acid cleaving enzyme)

chr4_-_58553553 1.393 ENSMUST00000107575.2
ENSMUST00000107574.1
ENSMUST00000147354.1
Lpar1


lysophosphatidic acid receptor 1


chr10_+_37139558 1.370 ENSMUST00000062667.3
5930403N24Rik
RIKEN cDNA 5930403N24 gene
chr12_+_72441852 1.366 ENSMUST00000162159.1
Lrrc9
leucine rich repeat containing 9
chr16_-_55283237 1.361 ENSMUST00000036412.3
Zpld1
zona pellucida like domain containing 1
chr6_+_8520008 1.338 ENSMUST00000162567.1
ENSMUST00000161217.1
Glcci1

glucocorticoid induced transcript 1

chr1_-_132707304 1.336 ENSMUST00000043189.7
Nfasc
neurofascin
chr2_-_121235689 1.327 ENSMUST00000142400.1
Trp53bp1
transformation related protein 53 binding protein 1
chr2_+_154548888 1.313 ENSMUST00000045116.4
ENSMUST00000109709.3
1700003F12Rik

RIKEN cDNA 1700003F12 gene

chr9_-_106891401 1.308 ENSMUST00000069036.7
Manf
mesencephalic astrocyte-derived neurotrophic factor
chr3_-_123672321 1.299 ENSMUST00000172537.1
ENSMUST00000029602.6
Ndst3

N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3

chr4_+_116720920 1.280 ENSMUST00000045542.6
ENSMUST00000106459.1
Tesk2

testis-specific kinase 2

chr4_-_126968124 1.266 ENSMUST00000106108.2
Zmym4
zinc finger, MYM-type 4
chr10_-_86011833 1.266 ENSMUST00000105304.1
ENSMUST00000061699.5
Bpifc

BPI fold containing family C

chr1_+_170308802 1.248 ENSMUST00000056991.5
1700015E13Rik
RIKEN cDNA 1700015E13 gene
chr17_-_47834682 1.241 ENSMUST00000066368.6
Mdfi
MyoD family inhibitor
chr4_+_110397661 1.239 ENSMUST00000106589.2
ENSMUST00000106587.2
ENSMUST00000106591.1
ENSMUST00000106592.1
Agbl4



ATP/GTP binding protein-like 4



chr5_-_138187177 1.232 ENSMUST00000110937.1
ENSMUST00000139276.1
ENSMUST00000048698.7
ENSMUST00000123415.1
Taf6



TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor



chr11_+_23666479 1.223 ENSMUST00000143117.1
Pus10
pseudouridylate synthase 10
chr16_-_45724600 1.222 ENSMUST00000096057.4
Tagln3
transgelin 3

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
6.9 20.7 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
4.5 13.6 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
3.8 11.5 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
3.2 9.6 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
2.9 11.4 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
2.3 13.6 GO:0006570 tyrosine metabolic process(GO:0006570)
2.0 6.1 GO:0090425 hepatocyte cell migration(GO:0002194) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
2.0 2.0 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
1.6 4.9 GO:0090274 positive regulation of somatostatin secretion(GO:0090274)
1.5 4.5 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
1.4 4.3 GO:1904956 regulation of midbrain dopaminergic neuron differentiation(GO:1904956) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
1.3 4.0 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
1.2 6.2 GO:0051661 maintenance of centrosome location(GO:0051661)
1.1 4.6 GO:0021648 zygotic determination of anterior/posterior axis, embryo(GO:0007354) cranial nerve formation(GO:0021603) vestibulocochlear nerve morphogenesis(GO:0021648)
1.0 9.4 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
1.0 4.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
1.0 3.0 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
1.0 3.9 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
1.0 1.0 GO:0003162 atrioventricular node development(GO:0003162)
1.0 4.9 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.9 5.2 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) phosphate ion transmembrane transport(GO:0035435) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.9 1.7 GO:0021856 cerebral cortex tangential migration using cell-axon interactions(GO:0021824) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) facioacoustic ganglion development(GO:1903375)
0.8 3.3 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.8 2.4 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.8 2.3 GO:0019343 cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344)
0.8 3.8 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.5 4.8 GO:0021830 interneuron migration from the subpallium to the cortex(GO:0021830)
0.5 31.4 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.5 4.7 GO:0097475 motor neuron migration(GO:0097475)
0.5 1.5 GO:1902915 negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.5 2.5 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.5 11.2 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.5 1.5 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.5 6.9 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.4 1.8 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.4 1.3 GO:0002014 vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure(GO:0002014)
0.4 0.9 GO:2001187 positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187)
0.4 5.1 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.4 2.1 GO:0015692 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.4 4.1 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.4 1.2 GO:0050748 negative regulation of receptor biosynthetic process(GO:0010871) transforming growth factor-beta secretion(GO:0038044) negative regulation of lipoprotein metabolic process(GO:0050748)
0.4 1.1 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.3 1.4 GO:0090472 nerve growth factor production(GO:0032902) dibasic protein processing(GO:0090472)
0.3 1.4 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.3 1.7 GO:1902965 regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
0.3 1.3 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.3 4.3 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.3 1.0 GO:0016554 cytidine to uridine editing(GO:0016554)
0.3 2.9 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) t-circle formation(GO:0090656)
0.3 1.0 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.3 0.6 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.3 5.3 GO:0003334 keratinocyte development(GO:0003334)
0.3 1.2 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.3 1.2 GO:0002035 brain renin-angiotensin system(GO:0002035)
0.3 1.8 GO:0034587 piRNA metabolic process(GO:0034587)
0.3 2.1 GO:0030242 pexophagy(GO:0030242)
0.3 0.6 GO:0002865 negative regulation of acute inflammatory response to antigenic stimulus(GO:0002865)
0.3 0.9 GO:0050975 sensory perception of touch(GO:0050975)
0.3 1.4 GO:0046208 spermine catabolic process(GO:0046208)
0.3 1.7 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.3 1.6 GO:0002329 pre-B cell differentiation(GO:0002329)
0.3 11.4 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.3 1.6 GO:0006172 ADP biosynthetic process(GO:0006172)
0.3 0.8 GO:1903011 negative regulation of bone development(GO:1903011)
0.3 3.9 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.3 0.8 GO:0021972 corticospinal neuron axon guidance through spinal cord(GO:0021972) positive regulation of negative chemotaxis(GO:0050924) induction of negative chemotaxis(GO:0050929) negative regulation of mononuclear cell migration(GO:0071676) negative regulation of retinal ganglion cell axon guidance(GO:0090260)
0.3 0.8 GO:0048818 embryonic nail plate morphogenesis(GO:0035880) positive regulation of hair follicle maturation(GO:0048818) positive regulation of catagen(GO:0051795) frontal suture morphogenesis(GO:0060364)
0.2 1.9 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.2 2.2 GO:0048733 sebaceous gland development(GO:0048733)
0.2 1.4 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.2 16.3 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.2 4.0 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.2 3.3 GO:0072189 ureter development(GO:0072189)
0.2 0.9 GO:0042420 dopamine catabolic process(GO:0042420)
0.2 0.9 GO:0072362 regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072362)
0.2 1.8 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.2 1.8 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.2 2.2 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.2 1.3 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.2 0.9 GO:0006742 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.2 0.9 GO:0035553 oxidative single-stranded RNA demethylation(GO:0035553)
0.2 1.7 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.2 1.6 GO:0030035 microspike assembly(GO:0030035)
0.2 0.6 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.2 1.0 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.2 2.6 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.2 4.4 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.2 4.8 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.2 2.7 GO:0045624 positive regulation of T-helper cell differentiation(GO:0045624)
0.2 2.1 GO:0060013 righting reflex(GO:0060013)
0.2 4.0 GO:0033194 response to hydroperoxide(GO:0033194)
0.2 0.3 GO:0033087 negative regulation of immature T cell proliferation(GO:0033087)
0.2 0.5 GO:0060060 post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.2 0.9 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.2 7.0 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.2 0.8 GO:1904659 glucose transmembrane transport(GO:1904659)
0.2 4.6 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.2 2.1 GO:0046548 retinal rod cell development(GO:0046548)
0.2 1.9 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.2 0.8 GO:0006538 glutamate catabolic process(GO:0006538)
0.1 1.3 GO:0042118 endothelial cell activation(GO:0042118)
0.1 0.7 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.1 0.6 GO:0007113 endomitotic cell cycle(GO:0007113)
0.1 1.0 GO:0016584 nucleosome positioning(GO:0016584)
0.1 3.8 GO:0097352 autophagosome maturation(GO:0097352)
0.1 2.9 GO:0060009 Sertoli cell development(GO:0060009)
0.1 0.9 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 0.3 GO:0060686 regulation of prostatic bud formation(GO:0060685) negative regulation of prostatic bud formation(GO:0060686)
0.1 0.9 GO:0046292 formaldehyde metabolic process(GO:0046292)
0.1 3.6 GO:0007608 sensory perception of smell(GO:0007608)
0.1 1.2 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.1 0.5 GO:0002667 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911)
0.1 0.5 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.1 1.6 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1 5.5 GO:0007528 neuromuscular junction development(GO:0007528)
0.1 1.9 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.1 0.6 GO:1903056 positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.1 0.5 GO:0051189 molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.1 1.0 GO:2000671 regulation of motor neuron apoptotic process(GO:2000671)
0.1 0.7 GO:0071285 cellular response to lithium ion(GO:0071285)
0.1 1.3 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.1 2.7 GO:0031365 N-terminal protein amino acid modification(GO:0031365)
0.1 0.4 GO:0021502 neural fold elevation formation(GO:0021502)
0.1 1.2 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 0.2 GO:0050923 regulation of negative chemotaxis(GO:0050923)
0.1 0.9 GO:0051923 sulfation(GO:0051923)
0.1 1.5 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 0.4 GO:0032570 response to progesterone(GO:0032570)
0.1 0.2 GO:0036292 DNA rewinding(GO:0036292)
0.1 0.2 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1 0.8 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 1.3 GO:0008045 motor neuron axon guidance(GO:0008045)
0.1 0.3 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.1 1.2 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.1 0.9 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.1 0.8 GO:0060539 diaphragm development(GO:0060539)
0.1 0.7 GO:1900112 regulation of histone H3-K9 trimethylation(GO:1900112) negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.1 1.1 GO:0030953 astral microtubule organization(GO:0030953)
0.1 0.7 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.1 0.9 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.1 0.3 GO:0052428 modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.1 0.8 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.1 1.3 GO:0048041 cell-substrate adherens junction assembly(GO:0007045) focal adhesion assembly(GO:0048041)
0.1 0.9 GO:0034308 fatty acid elongation(GO:0030497) primary alcohol metabolic process(GO:0034308)
0.1 1.5 GO:0007606 sensory perception of chemical stimulus(GO:0007606)
0.1 0.1 GO:0042713 sperm ejaculation(GO:0042713) negative regulation of gastric acid secretion(GO:0060455)
0.1 2.3 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.1 0.4 GO:0090527 actin filament reorganization(GO:0090527)
0.1 1.5 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.1 0.5 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.1 0.6 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 0.2 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.1 0.3 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.1 1.9 GO:0009409 response to cold(GO:0009409)
0.1 1.4 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.1 0.4 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.2 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.7 GO:0010225 response to UV-C(GO:0010225)
0.0 0.7 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.1 GO:1902605 heterotrimeric G-protein complex assembly(GO:1902605)
0.0 2.3 GO:0006940 regulation of smooth muscle contraction(GO:0006940)
0.0 5.1 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.0 0.3 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.4 GO:0061013 regulation of mRNA catabolic process(GO:0061013) positive regulation of mRNA catabolic process(GO:0061014)
0.0 0.9 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 1.6 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 2.0 GO:0002066 columnar/cuboidal epithelial cell development(GO:0002066)
0.0 1.2 GO:0002053 positive regulation of mesenchymal cell proliferation(GO:0002053)
0.0 0.2 GO:2000780 negative regulation of double-strand break repair(GO:2000780)
0.0 3.2 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 1.7 GO:1901998 toxin transport(GO:1901998)
0.0 3.2 GO:0006275 regulation of DNA replication(GO:0006275)
0.0 1.2 GO:0001919 regulation of receptor recycling(GO:0001919)
0.0 0.4 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.0 0.4 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.3 GO:0007602 phototransduction(GO:0007602)
0.0 0.7 GO:0023058 desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) negative adaptation of signaling pathway(GO:0022401) adaptation of signaling pathway(GO:0023058)
0.0 1.7 GO:0009060 aerobic respiration(GO:0009060)
0.0 4.2 GO:0046488 phosphatidylinositol metabolic process(GO:0046488)
0.0 1.0 GO:0006284 base-excision repair(GO:0006284)
0.0 0.9 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.2 GO:0098734 protein depalmitoylation(GO:0002084) negative regulation of Golgi to plasma membrane protein transport(GO:0042997) negative regulation of establishment of protein localization to plasma membrane(GO:0090005) macromolecule depalmitoylation(GO:0098734)
0.0 1.3 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.3 GO:0035036 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036)
0.0 1.5 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 1.8 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 0.6 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.0 0.5 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 1.1 GO:0050868 negative regulation of T cell activation(GO:0050868)
0.0 0.1 GO:0003374 dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374) response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579)
0.0 0.6 GO:0097320 membrane tubulation(GO:0097320)
0.0 0.2 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.0 0.1 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.0 1.1 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 0.3 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.6 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.0 0.7 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 2.2 GO:0010921 regulation of phosphatase activity(GO:0010921)
0.0 1.1 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.0 0.6 GO:0042733 embryonic digit morphogenesis(GO:0042733)
0.0 0.7 GO:0008542 visual learning(GO:0008542)
0.0 0.1 GO:0009098 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.0 0.6 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.2 GO:0070475 rRNA base methylation(GO:0070475)
0.0 1.0 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 0.2 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.8 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.2 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.7 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 1.2 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.1 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 1.1 GO:0007050 cell cycle arrest(GO:0007050)
0.0 1.0 GO:0007098 centrosome cycle(GO:0007098)
0.0 0.0 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.0 0.5 GO:0016574 histone ubiquitination(GO:0016574)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.4 13.6 GO:0060187 cell pole(GO:0060187)
1.6 6.2 GO:0008623 CHRAC(GO:0008623)
1.3 4.0 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
1.2 6.2 GO:0036449 microtubule minus-end(GO:0036449)
0.7 4.2 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.5 13.6 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.5 2.4 GO:0031523 Myb complex(GO:0031523)
0.4 37.2 GO:0070469 respiratory chain(GO:0070469)
0.4 2.1 GO:0070826 paraferritin complex(GO:0070826)
0.4 1.2 GO:0034684 integrin alphav-beta5 complex(GO:0034684)
0.4 3.8 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.4 21.2 GO:0016459 myosin complex(GO:0016459)
0.3 4.9 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.3 1.3 GO:0097454 Schwann cell microvillus(GO:0097454)
0.3 1.6 GO:0097226 sperm mitochondrial sheath(GO:0097226)
0.3 2.8 GO:0030478 actin cap(GO:0030478)
0.3 1.7 GO:0005726 perichromatin fibrils(GO:0005726)
0.3 1.9 GO:0070695 FHF complex(GO:0070695)
0.3 1.8 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.2 3.5 GO:0051286 cell tip(GO:0051286)
0.2 0.6 GO:1990047 spindle matrix(GO:1990047)
0.2 1.0 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.2 3.1 GO:0005614 interstitial matrix(GO:0005614)
0.2 0.9 GO:0072487 MSL complex(GO:0072487)
0.1 0.9 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 0.4 GO:0097524 sperm plasma membrane(GO:0097524)
0.1 0.9 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.1 0.4 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.1 0.8 GO:0032807 DNA ligase IV complex(GO:0032807)
0.1 1.6 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 1.8 GO:0042788 polysomal ribosome(GO:0042788)
0.1 5.3 GO:0002102 podosome(GO:0002102)
0.1 3.1 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 0.5 GO:1990032 parallel fiber(GO:1990032)
0.1 1.1 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 4.6 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 1.9 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 15.6 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.1 1.4 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.1 8.1 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 2.0 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 0.9 GO:0032797 SMN complex(GO:0032797)
0.1 3.4 GO:0097440 apical dendrite(GO:0097440)
0.1 1.1 GO:0001772 immunological synapse(GO:0001772)
0.1 1.3 GO:0042101 T cell receptor complex(GO:0042101)
0.1 6.3 GO:0031594 neuromuscular junction(GO:0031594)
0.1 0.5 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 0.5 GO:0001739 sex chromatin(GO:0001739)
0.1 1.2 GO:0032279 asymmetric synapse(GO:0032279)
0.1 0.5 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.1 0.9 GO:0043196 varicosity(GO:0043196)
0.1 0.9 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.6 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 3.0 GO:0000786 nucleosome(GO:0000786)
0.0 1.6 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 0.7 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 2.1 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.8 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.8 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.7 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.4 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 1.3 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.6 GO:0036038 MKS complex(GO:0036038)
0.0 0.8 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.5 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.5 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 1.8 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.4 GO:0033270 paranode region of axon(GO:0033270)
0.0 4.3 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.6 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.2 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0 0.7 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.2 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 2.3 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 4.4 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.6 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.3 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.1 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.2 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.2 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 1.5 GO:0000792 heterochromatin(GO:0000792)
0.0 0.2 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.2 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.2 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.2 GO:0042588 zymogen granule(GO:0042588)
0.0 0.5 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.2 GO:0043596 nuclear replication fork(GO:0043596)
0.0 0.4 GO:0032420 stereocilium(GO:0032420)
0.0 0.9 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 6.2 GO:0005911 cell-cell junction(GO:0005911)
0.0 0.1 GO:0070652 HAUS complex(GO:0070652)
0.0 0.2 GO:0030673 axolemma(GO:0030673)
0.0 0.7 GO:0005769 early endosome(GO:0005769)
0.0 0.7 GO:0032993 protein-DNA complex(GO:0032993)
0.0 1.0 GO:0043204 perikaryon(GO:0043204)
0.0 1.5 GO:0043679 axon terminus(GO:0043679)
0.0 0.3 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 1.5 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.3 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 2.1 GO:0005681 spliceosomal complex(GO:0005681)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.2 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
1.7 13.9 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
1.1 32.1 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
1.0 13.6 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
1.0 3.9 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.8 5.8 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.8 4.7 GO:0004984 olfactory receptor activity(GO:0004984)
0.6 2.5 GO:0038049 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.6 5.4 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.6 2.4 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.6 5.1 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.6 6.1 GO:0050693 LBD domain binding(GO:0050693)
0.5 2.7 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.5 34.4 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.5 2.5 GO:0015440 peptide-transporting ATPase activity(GO:0015440)
0.5 4.0 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.5 1.5 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.5 1.4 GO:0046592 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
0.4 2.1 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.4 1.2 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.4 3.0 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.4 21.7 GO:0030507 spectrin binding(GO:0030507)
0.4 4.1 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.4 2.9 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.3 17.1 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.3 4.7 GO:0045499 chemorepellent activity(GO:0045499)
0.3 1.3 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.3 1.3 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.3 0.6 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.3 1.0 GO:0008311 double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.3 0.6 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.3 0.9 GO:0005118 sevenless binding(GO:0005118)
0.3 0.9 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.3 0.9 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.3 9.9 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.3 5.0 GO:0005540 hyaluronic acid binding(GO:0005540)
0.3 1.3 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.3 1.0 GO:0051378 serotonin binding(GO:0051378)
0.2 1.7 GO:0034056 estrogen response element binding(GO:0034056)
0.2 4.7 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.2 1.0 GO:0004126 cytidine deaminase activity(GO:0004126)
0.2 1.2 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.2 0.7 GO:0098809 nitrite reductase activity(GO:0098809)
0.2 0.7 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.2 5.1 GO:0008327 methyl-CpG binding(GO:0008327)
0.2 0.9 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.2 2.0 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) neurotrophin TRK receptor binding(GO:0005167) neurotrophin TRKA receptor binding(GO:0005168)
0.2 0.9 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.2 0.9 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.2 1.6 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.2 1.0 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.2 1.6 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.2 2.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.2 1.2 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.2 1.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.2 1.1 GO:0001849 complement component C1q binding(GO:0001849)
0.2 4.8 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.2 4.1 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.2 0.7 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.2 0.8 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.2 2.6 GO:0070410 co-SMAD binding(GO:0070410)
0.2 3.3 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 1.6 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 4.5 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1 1.2 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 4.9 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 4.6 GO:0070888 E-box binding(GO:0070888)
0.1 1.5 GO:0070513 death domain binding(GO:0070513)
0.1 2.8 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.1 1.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 2.6 GO:0042605 peptide antigen binding(GO:0042605)
0.1 4.8 GO:0032452 histone demethylase activity(GO:0032452)
0.1 0.8 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.1 1.8 GO:0005542 folic acid binding(GO:0005542)
0.1 2.9 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.1 0.9 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.1 1.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 1.4 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 1.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.6 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.1 1.8 GO:0001056 RNA polymerase III activity(GO:0001056)
0.1 0.8 GO:0015197 peptide transporter activity(GO:0015197)
0.1 1.6 GO:0070412 R-SMAD binding(GO:0070412)
0.1 2.5 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 5.5 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 2.2 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 1.2 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 1.2 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 0.2 GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
0.1 2.7 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 0.4 GO:0001515 opioid peptide activity(GO:0001515)
0.1 0.4 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.1 12.9 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 0.8 GO:0050811 GABA receptor binding(GO:0050811)
0.1 0.8 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.1 0.6 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.1 0.7 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 0.6 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 0.7 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 2.8 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.0 2.0 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.6 GO:0043495 protein anchor(GO:0043495)
0.0 0.4 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 1.2 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.5 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 3.2 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.2 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.6 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.0 3.8 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.0 2.7 GO:0008276 protein methyltransferase activity(GO:0008276)
0.0 0.4 GO:0070700 BMP receptor binding(GO:0070700)
0.0 1.2 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.7 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 1.8 GO:0004386 helicase activity(GO:0004386)
0.0 1.0 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.1 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.0 1.3 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.2 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0 0.6 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 1.0 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.2 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.4 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.0 1.0 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 2.3 GO:0051117 ATPase binding(GO:0051117)
0.0 2.3 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.5 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 6.4 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.3 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.1 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475) peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.0 0.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.1 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.3 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 0.2 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.2 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.1 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 0.1 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.4 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.1 GO:0035198 miRNA binding(GO:0035198)
0.0 2.5 GO:0051015 actin filament binding(GO:0051015)
0.0 0.2 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.2 GO:0008143 poly(A) binding(GO:0008143)
0.0 1.5 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.5 GO:0005507 copper ion binding(GO:0005507)
0.0 0.1 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.8 GO:0004004 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.4 GO:0042393 histone binding(GO:0042393)
0.0 0.4 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.1 GO:0051400 BH domain binding(GO:0051400)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 25.9 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.5 13.9 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.4 16.0 PID_ARF6_PATHWAY Arf6 signaling events
0.4 12.4 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway
0.4 21.4 PID_CD8_TCR_DOWNSTREAM_PATHWAY Downstream signaling in naïve CD8+ T cells
0.2 3.9 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.1 1.8 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.1 5.4 NABA_COLLAGENS Genes encoding collagen proteins
0.1 3.2 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.1 1.6 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.1 5.1 PID_FANCONI_PATHWAY Fanconi anemia pathway
0.1 2.1 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.1 4.0 ST_DIFFERENTIATION_PATHWAY_IN_PC12_CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.1 2.6 PID_AURORA_A_PATHWAY Aurora A signaling
0.1 8.2 PID_E2F_PATHWAY E2F transcription factor network
0.1 3.5 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.1 4.3 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.1 5.0 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.1 4.0 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.1 0.6 PID_S1P_S1P4_PATHWAY S1P4 pathway
0.1 4.3 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.1 5.0 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.1 2.1 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 1.5 PID_RAS_PATHWAY Regulation of Ras family activation
0.1 1.7 ST_GA13_PATHWAY G alpha 13 Pathway
0.1 4.2 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.7 PID_INTEGRIN_CS_PATHWAY Integrin family cell surface interactions
0.0 1.4 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 6.6 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 2.1 PID_PLK1_PATHWAY PLK1 signaling events
0.0 1.2 ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY PI3K Pathway
0.0 1.4 PID_LYSOPHOSPHOLIPID_PATHWAY LPA receptor mediated events
0.0 0.8 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.7 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.0 0.3 PID_AR_NONGENOMIC_PATHWAY Nongenotropic Androgen signaling
0.0 1.3 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.0 0.3 ST_ADRENERGIC Adrenergic Pathway
0.0 0.8 PID_ARF_3PATHWAY Arf1 pathway
0.0 0.3 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.0 0.3 PID_ER_NONGENOMIC_PATHWAY Plasma membrane estrogen receptor signaling
0.0 1.2 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.0 0.2 PID_ATM_PATHWAY ATM pathway
0.0 0.7 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.6 PID_LKB1_PATHWAY LKB1 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 10.8 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.3 1.8 REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.3 2.5 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.3 2.2 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.2 3.2 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.2 6.9 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.2 13.7 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.2 2.2 REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.2 3.9 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.2 5.7 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.2 0.5 REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.2 1.4 REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 3.8 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 5.4 REACTOME_G1_PHASE Genes involved in G1 Phase
0.1 0.9 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 1.2 REACTOME_PECAM1_INTERACTIONS Genes involved in PECAM1 interactions
0.1 0.3 REACTOME_HORMONE_LIGAND_BINDING_RECEPTORS Genes involved in Hormone ligand-binding receptors
0.1 1.5 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.1 0.8 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 3.5 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 0.5 REACTOME_DSCAM_INTERACTIONS Genes involved in DSCAM interactions
0.1 0.6 REACTOME_THROMBIN_SIGNALLING_THROUGH_PROTEINASE_ACTIVATED_RECEPTORS_PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.1 1.1 REACTOME_REGULATION_OF_KIT_SIGNALING Genes involved in Regulation of KIT signaling
0.1 1.8 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 2.0 REACTOME_PROLONGED_ERK_ACTIVATION_EVENTS Genes involved in Prolonged ERK activation events
0.1 4.0 REACTOME_RECYCLING_PATHWAY_OF_L1 Genes involved in Recycling pathway of L1
0.1 1.4 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.1 2.8 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 5.5 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.1 1.8 REACTOME_RNA_POL_III_CHAIN_ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.1 2.2 REACTOME_ENOS_ACTIVATION_AND_REGULATION Genes involved in eNOS activation and regulation
0.1 8.8 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 14.3 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.1 0.6 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 0.5 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION_IN_TLR7_8_OR_9_SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1 0.9 REACTOME_NOREPINEPHRINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 1.2 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 0.3 REACTOME_DESTABILIZATION_OF_MRNA_BY_AUF1_HNRNP_D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.1 2.4 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.1 0.7 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 1.3 REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 2.5 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 1.6 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 0.8 REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 0.5 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 0.7 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 0.3 REACTOME_OLFACTORY_SIGNALING_PATHWAY Genes involved in Olfactory Signaling Pathway
0.1 1.6 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 1.0 REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 1.6 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 2.2 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 1.6 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.7 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.6 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.1 REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.5 REACTOME_FORMATION_OF_INCISION_COMPLEX_IN_GG_NER Genes involved in Formation of incision complex in GG-NER
0.0 0.3 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.3 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.2 REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.2 REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.3 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.2 REACTOME_METABOLISM_OF_NON_CODING_RNA Genes involved in Metabolism of non-coding RNA
0.0 1.2 REACTOME_L1CAM_INTERACTIONS Genes involved in L1CAM interactions
0.0 0.2 REACTOME_KINESINS Genes involved in Kinesins
0.0 0.3 REACTOME_EXTENSION_OF_TELOMERES Genes involved in Extension of Telomeres
0.0 0.2 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.5 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening