Motif ID: Nr0b1

Z-value: 1.086


Transcription factors associated with Nr0b1:

Gene SymbolEntrez IDGene Name
Nr0b1 ENSMUSG00000025056.4 Nr0b1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr0b1mm10_v2_chrX_+_86191764_861917820.161.6e-01Click!


Activity profile for motif Nr0b1.

activity profile for motif Nr0b1


Sorted Z-values histogram for motif Nr0b1

Sorted Z-values for motif Nr0b1



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr0b1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_-_45844228 15.295 ENSMUST00000076333.5
 Phldb2
pleckstrin homology-like domain, family B, member 2
chr16_-_45844303 14.948 ENSMUST00000036355.6
 Phldb2
pleckstrin homology-like domain, family B, member 2
chr11_+_102604370 11.787 ENSMUST00000057893.5
 Fzd2
frizzled homolog 2 (Drosophila)
chr7_+_79500081 11.599 ENSMUST00000181511.2
ENSMUST00000182937.1
 AI854517

expressed sequence AI854517

chr9_+_80165079 11.015 ENSMUST00000184480.1
 Myo6
myosin VI
chr7_+_79500018 10.828 ENSMUST00000182495.1
ENSMUST00000183043.1
 AI854517

expressed sequence AI854517

chr9_+_80165013 9.873 ENSMUST00000035889.8
ENSMUST00000113268.1
 Myo6

myosin VI

chr5_+_64803513 8.975 ENSMUST00000165536.1
 Klf3
Kruppel-like factor 3 (basic)
chr1_-_9700209 8.211 ENSMUST00000088658.4
 Mybl1
myeloblastosis oncogene-like 1
chrX_-_145505175 7.854 ENSMUST00000143610.1
 Amot
angiomotin
chr18_+_35829798 6.919 ENSMUST00000060722.6
 Cxxc5
CXXC finger 5
chr4_-_132422484 6.815 ENSMUST00000102568.3
 Phactr4
phosphatase and actin regulator 4
chr17_-_70851189 6.503 ENSMUST00000059775.8
 Tgif1
TGFB-induced factor homeobox 1
chr10_-_81350389 6.474 ENSMUST00000020454.4
ENSMUST00000105324.2
ENSMUST00000154609.2
ENSMUST00000105323.1
 Hmg20b



high mobility group 20B



chr4_-_132422394 6.372 ENSMUST00000152271.1
ENSMUST00000084170.5
 Phactr4

phosphatase and actin regulator 4

chr1_+_42697146 6.189 ENSMUST00000054883.2
 Pou3f3
POU domain, class 3, transcription factor 3
chr4_+_116221633 5.918 ENSMUST00000030464.7
 Pik3r3
phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55)
chr14_+_11553523 5.879 ENSMUST00000022264.6
 Ptprg
protein tyrosine phosphatase, receptor type, G
chr13_-_29984219 5.680 ENSMUST00000146092.1
 E2f3
E2F transcription factor 3
chr3_-_123690806 5.523 ENSMUST00000154668.1
 Ndst3
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr4_+_116221689 5.459 ENSMUST00000106490.2
 Pik3r3
phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55)
chr19_-_46039442 5.181 ENSMUST00000137771.1
 Ldb1
LIM domain binding 1
chr11_+_94328242 5.181 ENSMUST00000021227.5
 Ankrd40
ankyrin repeat domain 40
chr7_+_28180226 4.912 ENSMUST00000172467.1
 Dyrk1b
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr11_+_94327984 4.824 ENSMUST00000107818.2
ENSMUST00000051221.6
 Ankrd40

ankyrin repeat domain 40

chr5_-_115436508 4.571 ENSMUST00000078701.3
 4930430O22Rik
RIKEN cDNA 4930430O22 gene
chr7_+_19094594 4.495 ENSMUST00000049454.5
 Six5
sine oculis-related homeobox 5
chr7_+_28180272 4.249 ENSMUST00000173223.1
 Dyrk1b
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr4_-_123750236 4.243 ENSMUST00000102636.3
 Akirin1
akirin 1
chr4_+_116221590 4.174 ENSMUST00000147292.1
 Pik3r3
phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55)
chr11_+_77930800 3.907 ENSMUST00000093995.3
ENSMUST00000000646.7
 Sez6

seizure related gene 6

chr3_+_86224665 3.886 ENSMUST00000107635.1
 Lrba
LPS-responsive beige-like anchor
chr2_-_54085542 3.865 ENSMUST00000100089.2
 Rprm
reprimo, TP53 dependent G2 arrest mediator candidate
chr6_+_47454320 3.635 ENSMUST00000031697.8
 Cul1
cullin 1
chr7_+_82867327 3.377 ENSMUST00000082237.5
 Mex3b
mex3 homolog B (C. elegans)
chr5_-_99037035 3.153 ENSMUST00000031277.6
 Prkg2
protein kinase, cGMP-dependent, type II
chr4_+_148130883 3.037 ENSMUST00000084129.2
 Mad2l2
MAD2 mitotic arrest deficient-like 2
chr15_-_38078842 3.013 ENSMUST00000110336.2
 Ubr5
ubiquitin protein ligase E3 component n-recognin 5
chr5_-_99037342 2.958 ENSMUST00000161490.1
 Prkg2
protein kinase, cGMP-dependent, type II
chr5_+_30913398 2.940 ENSMUST00000031055.5
 Emilin1
elastin microfibril interfacer 1
chr17_-_23745829 2.604 ENSMUST00000046525.8
 Kremen2
kringle containing transmembrane protein 2
chr14_+_75845296 2.401 ENSMUST00000142061.1
 Tpt1
tumor protein, translationally-controlled 1
chr2_+_71786923 2.378 ENSMUST00000112101.1
ENSMUST00000028522.3
 Itga6

integrin alpha 6

chr13_+_94358943 2.363 ENSMUST00000022196.3
 Ap3b1
adaptor-related protein complex 3, beta 1 subunit
chr18_+_80046854 2.262 ENSMUST00000070219.7
 Pard6g
par-6 partitioning defective 6 homolog gamma (C. elegans)
chr7_-_65371210 2.249 ENSMUST00000102592.3
 Tjp1
tight junction protein 1
chr17_-_80728026 2.224 ENSMUST00000112389.2
ENSMUST00000025089.7
 Map4k3

mitogen-activated protein kinase kinase kinase kinase 3

chr16_+_44173239 2.179 ENSMUST00000119746.1
 Gm608
predicted gene 608
chr13_-_94358818 2.145 ENSMUST00000059598.2
 Gm9776
predicted gene 9776
chr4_-_138913915 2.125 ENSMUST00000097830.3
 Otud3
OTU domain containing 3
chr17_+_29490812 2.049 ENSMUST00000024811.6
 Pim1
proviral integration site 1
chr5_+_110230975 2.045 ENSMUST00000031474.7
ENSMUST00000086674.5
 Ankle2

ankyrin repeat and LEM domain containing 2

chr11_-_70687917 2.023 ENSMUST00000108545.2
ENSMUST00000120261.1
ENSMUST00000036299.7
ENSMUST00000119120.1
ENSMUST00000100933.3
 Camta2




calmodulin binding transcription activator 2




chr12_+_49385174 1.832 ENSMUST00000110746.1
 3110039M20Rik
RIKEN cDNA 3110039M20 gene
chr11_-_74723829 1.752 ENSMUST00000102520.2
 Pafah1b1
platelet-activating factor acetylhydrolase, isoform 1b, subunit 1
chr1_+_59764264 1.674 ENSMUST00000087435.5
 Bmpr2
bone morphogenetic protein receptor, type II (serine/threonine kinase)
chr11_+_50237002 1.650 ENSMUST00000180443.1
 Gm26542
predicted gene, 26542
chr11_+_105181793 1.602 ENSMUST00000092537.3
ENSMUST00000015107.6
ENSMUST00000145048.1
 Tlk2


tousled-like kinase 2 (Arabidopsis)


chr2_+_4718145 1.465 ENSMUST00000056914.6
 Bend7
BEN domain containing 7
chr13_-_64274879 1.421 ENSMUST00000109770.1
 Cdc14b
CDC14 cell division cycle 14B
chr11_+_107547925 1.382 ENSMUST00000100305.1
ENSMUST00000075012.1
ENSMUST00000106746.1
 Helz


helicase with zinc finger domain


chr2_+_129198757 1.363 ENSMUST00000028880.3
 Slc20a1
solute carrier family 20, member 1
chr4_-_135971894 1.307 ENSMUST00000105852.1
 Lypla2
lysophospholipase 2
chr1_+_140246216 1.222 ENSMUST00000119786.1
ENSMUST00000120796.1
ENSMUST00000060201.8
ENSMUST00000120709.1
 Kcnt2



potassium channel, subfamily T, member 2



chr19_+_45015198 1.195 ENSMUST00000179108.1
 Lzts2
leucine zipper, putative tumor suppressor 2
chr5_+_121711609 1.047 ENSMUST00000051950.7
 Atxn2
ataxin 2
chr8_-_95434869 0.962 ENSMUST00000034249.6
 Gtl3
gene trap locus 3
chr15_+_35371498 0.961 ENSMUST00000048646.7
 Vps13b
vacuolar protein sorting 13B (yeast)
chr4_-_148130678 0.958 ENSMUST00000030862.4
 Draxin
dorsal inhibitory axon guidance protein
chr17_+_34898463 0.957 ENSMUST00000114033.2
ENSMUST00000078061.6
 Ehmt2

euchromatic histone lysine N-methyltransferase 2

chr15_+_80711292 0.895 ENSMUST00000067689.7
 Tnrc6b
trinucleotide repeat containing 6b
chr4_-_129696817 0.849 ENSMUST00000102588.3
 Tmem39b
transmembrane protein 39b
chr11_+_23306884 0.642 ENSMUST00000180046.1
 Usp34
ubiquitin specific peptidase 34
chr11_+_24078173 0.617 ENSMUST00000109514.1
 Bcl11a
B cell CLL/lymphoma 11A (zinc finger protein)
chr11_+_105181527 0.607 ENSMUST00000106941.2
 Tlk2
tousled-like kinase 2 (Arabidopsis)
chr19_-_6077183 0.379 ENSMUST00000025711.5
ENSMUST00000160590.1
 Vps51

vacuolar protein sorting 51 homolog (S. cerevisiae)

chr8_-_85080652 0.345 ENSMUST00000152785.1
 Wdr83
WD repeat domain containing 83
chr2_+_30066419 0.303 ENSMUST00000067996.6
 Set
SET nuclear oncogene
chr2_+_85037448 0.278 ENSMUST00000168266.1
ENSMUST00000130729.1
 Ssrp1

structure specific recognition protein 1

chr11_+_23306910 0.269 ENSMUST00000137823.1
 Usp34
ubiquitin specific peptidase 34
chr13_-_55488038 0.259 ENSMUST00000109921.2
ENSMUST00000109923.2
ENSMUST00000021950.8
 Dbn1


drebrin 1


chr8_-_85080679 0.251 ENSMUST00000093357.5
 Wdr83
WD repeat domain containing 83
chr7_+_19359740 0.202 ENSMUST00000140836.1
 Ppp1r13l
protein phosphatase 1, regulatory (inhibitor) subunit 13 like
chr5_+_31193227 0.199 ENSMUST00000031029.8
ENSMUST00000133711.1
ENSMUST00000132471.1
 Snx17


sorting nexin 17


chr9_-_44881274 0.186 ENSMUST00000002095.3
ENSMUST00000114689.1
ENSMUST00000128768.1
 Kmt2a


lysine (K)-specific methyltransferase 2A


chr8_-_105707933 0.153 ENSMUST00000013299.9
 Enkd1
enkurin domain containing 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
4.3 30.2 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
3.3 13.2 GO:2001045 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
2.4 11.8 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223) hard palate development(GO:0060022)
2.0 7.9 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
1.6 20.9 GO:0071257 cellular response to electrical stimulus(GO:0071257)
1.5 6.2 GO:0072236 DCT cell differentiation(GO:0072069) metanephric loop of Henle development(GO:0072236) metanephric DCT cell differentiation(GO:0072240)
1.3 5.2 GO:0043973 histone H3-K4 acetylation(GO:0043973)
1.0 3.0 GO:1902915 negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.9 5.7 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.9 5.5 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.9 6.1 GO:2001225 cellular hypotonic response(GO:0071476) regulation of chloride transport(GO:2001225)
0.8 2.4 GO:0048007 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.8 3.0 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.7 2.1 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.7 2.0 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.6 2.4 GO:2000383 regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.6 1.8 GO:0043622 cortical microtubule organization(GO:0043622)
0.6 3.4 GO:0072697 protein localization to cell cortex(GO:0072697)
0.6 1.7 GO:0014916 regulation of lung blood pressure(GO:0014916) negative regulation of cell proliferation involved in heart morphogenesis(GO:2000137) cell proliferation involved in heart valve development(GO:2000793)
0.5 1.0 GO:0036166 phenotypic switching(GO:0036166)
0.4 2.0 GO:2000138 positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
0.4 6.5 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.4 2.4 GO:0035878 nail development(GO:0035878)
0.4 15.6 GO:0043551 regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.4 6.5 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.3 4.5 GO:0014842 regulation of skeletal muscle satellite cell proliferation(GO:0014842)
0.2 9.2 GO:0007520 myoblast fusion(GO:0007520)
0.2 1.3 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.2 2.2 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.2 2.2 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.2 3.9 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.2 1.4 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.1 5.2 GO:1901998 toxin transport(GO:1901998)
0.1 2.9 GO:0070207 protein homotrimerization(GO:0070207)
0.1 3.6 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.1 2.0 GO:0014898 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.1 0.3 GO:0010643 cell communication by chemical coupling(GO:0010643) negative regulation of locomotion involved in locomotory behavior(GO:0090327)
0.1 1.4 GO:0006817 phosphate ion transport(GO:0006817)
0.1 0.9 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.1 1.0 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.1 1.0 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.2 GO:0043974 histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674) positive regulation of response to drug(GO:2001025)
0.0 0.9 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 2.6 GO:0030279 negative regulation of ossification(GO:0030279)
0.0 3.9 GO:0007050 cell cycle arrest(GO:0007050)
0.0 3.9 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 3.9 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0 2.2 GO:0034612 response to tumor necrosis factor(GO:0034612)
0.0 1.2 GO:1900181 negative regulation of protein localization to nucleus(GO:1900181)
0.0 0.2 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.0 9.0 GO:0000122 negative regulation of transcription from RNA polymerase II promoter(GO:0000122)
0.0 0.4 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.2 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 8.2 GO:0000278 mitotic cell cycle(GO:0000278)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 30.2 GO:0045180 basal cortex(GO:0045180)
1.6 6.5 GO:0002111 BRCA2-BRAF35 complex(GO:0002111)
0.9 3.6 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.8 20.9 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.7 15.6 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.3 1.9 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.3 1.8 GO:0000235 astral microtubule(GO:0000235)
0.3 2.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.2 2.4 GO:0045298 tubulin complex(GO:0045298)
0.2 2.4 GO:0030056 hemidesmosome(GO:0030056)
0.2 2.4 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.2 7.9 GO:0008180 COP9 signalosome(GO:0008180)
0.1 2.9 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.1 3.9 GO:0097440 apical dendrite(GO:0097440)
0.1 0.4 GO:1990745 EARP complex(GO:1990745)
0.1 0.3 GO:1902737 dendritic filopodium(GO:1902737)
0.1 12.5 GO:0030027 lamellipodium(GO:0030027)
0.0 10.4 GO:0031965 nuclear membrane(GO:0031965)
0.0 2.2 GO:0005882 intermediate filament(GO:0005882)
0.0 5.7 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 1.7 GO:0009925 basal plasma membrane(GO:0009925)
0.0 11.7 GO:0005925 focal adhesion(GO:0005925)
0.0 5.2 GO:0031252 cell leading edge(GO:0031252)
0.0 2.3 GO:0005923 bicellular tight junction(GO:0005923)
0.0 4.3 GO:0005802 trans-Golgi network(GO:0005802)
0.0 1.2 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 2.0 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.6 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 29.5 GO:0005654 nucleoplasm(GO:0005654)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 13.2 GO:0072542 protein phosphatase activator activity(GO:0072542)
2.2 15.6 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
1.6 7.9 GO:0043532 angiostatin binding(GO:0043532)
1.5 6.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
1.4 5.5 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
1.0 8.2 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.6 2.9 GO:0098634 protein binding involved in cell-matrix adhesion(GO:0098634)
0.6 5.2 GO:0030274 LIM domain binding(GO:0030274)
0.5 11.8 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.5 1.4 GO:0005436 sodium:phosphate symporter activity(GO:0005436) sodium:inorganic phosphate symporter activity(GO:0015319)
0.4 9.5 GO:0008432 JUN kinase binding(GO:0008432)
0.4 1.8 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.3 1.6 GO:0038132 neuregulin binding(GO:0038132)
0.3 6.5 GO:0000400 four-way junction DNA binding(GO:0000400)
0.2 2.2 GO:0071253 connexin binding(GO:0071253)
0.2 1.7 GO:0098821 BMP receptor activity(GO:0098821)
0.2 3.0 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.2 6.2 GO:0071837 HMG box domain binding(GO:0071837)
0.2 2.0 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.2 3.4 GO:0032794 GTPase activating protein binding(GO:0032794)
0.2 2.2 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.2 9.2 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.2 20.9 GO:0003774 motor activity(GO:0003774)
0.1 1.0 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.1 1.3 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 1.2 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 2.4 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.1 3.9 GO:0051018 protein kinase A binding(GO:0051018)
0.1 1.0 GO:0050692 DBD domain binding(GO:0050692)
0.1 2.0 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.1 6.1 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.2 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 13.9 GO:0045296 cadherin binding(GO:0045296)
0.0 5.7 GO:0001047 core promoter binding(GO:0001047)
0.0 2.2 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 22.4 GO:0043565 sequence-specific DNA binding(GO:0043565)
0.0 3.6 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 2.4 GO:0008017 microtubule binding(GO:0008017)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 14.4 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.4 15.6 PID_TRAIL_PATHWAY TRAIL signaling pathway
0.3 20.2 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.3 2.4 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.2 1.7 PID_ALK2_PATHWAY ALK2 signaling events
0.2 3.6 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin
0.1 8.2 PID_IL4_2PATHWAY IL4-mediated signaling events
0.1 2.0 PID_IL5_PATHWAY IL5-mediated signaling events
0.1 2.2 PID_NEPHRIN_NEPH1_PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.1 6.5 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.1 5.7 PID_RB_1PATHWAY Regulation of retinoblastoma protein
0.1 3.8 PID_PLK1_PATHWAY PLK1 signaling events
0.0 1.8 PID_REELIN_PATHWAY Reelin signaling pathway
0.0 2.2 PID_TNF_PATHWAY TNF receptor signaling pathway
0.0 1.0 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 15.6 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
1.1 20.9 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.5 5.7 REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.4 3.6 REACTOME_PROLACTIN_RECEPTOR_SIGNALING Genes involved in Prolactin receptor signaling
0.3 10.1 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.3 6.1 REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.2 6.5 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 5.5 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 11.7 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 1.7 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.1 2.3 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.1 6.5 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 2.4 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.9 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 1.0 REACTOME_RNA_POL_I_TRANSCRIPTION_INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 1.8 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.3 REACTOME_ELONGATION_ARREST_AND_RECOVERY Genes involved in Elongation arrest and recovery
0.0 1.9 REACTOME_DNA_REPAIR Genes involved in DNA Repair
0.0 1.4 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides