Motif ID: Nr2c2

Z-value: 1.164


Transcription factors associated with Nr2c2:

Gene SymbolEntrez IDGene Name
Nr2c2 ENSMUSG00000005893.8 Nr2c2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr2c2mm10_v2_chr6_+_92092369_92092433-0.379.9e-04Click!


Activity profile for motif Nr2c2.

activity profile for motif Nr2c2


Sorted Z-values histogram for motif Nr2c2

Sorted Z-values for motif Nr2c2



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr2c2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_+_61485431 18.339 ENSMUST00000064783.3
ENSMUST00000040522.6
Mfap4

microfibrillar-associated protein 4

chr7_+_79500081 12.704 ENSMUST00000181511.2
ENSMUST00000182937.1
AI854517

expressed sequence AI854517

chr4_-_97778042 12.683 ENSMUST00000146447.1
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr7_+_79500018 12.604 ENSMUST00000182495.1
ENSMUST00000183043.1
AI854517

expressed sequence AI854517

chr1_-_138847579 12.383 ENSMUST00000093486.3
ENSMUST00000046870.6
Lhx9

LIM homeobox protein 9

chr14_-_52020698 11.931 ENSMUST00000067549.7
Zfp219
zinc finger protein 219
chr3_-_52104891 9.230 ENSMUST00000121440.1
Maml3
mastermind like 3 (Drosophila)
chr14_+_65806066 9.126 ENSMUST00000139644.1
Pbk
PDZ binding kinase
chr1_-_120120138 9.101 ENSMUST00000112648.1
ENSMUST00000128408.1
Dbi

diazepam binding inhibitor

chr6_-_48841373 9.067 ENSMUST00000166247.1
Tmem176b
transmembrane protein 176B
chr11_+_80300866 8.371 ENSMUST00000017836.7
Rhbdl3
rhomboid, veinlet-like 3 (Drosophila)
chr17_+_35049966 8.115 ENSMUST00000007257.9
Clic1
chloride intracellular channel 1
chr13_-_24761861 7.932 ENSMUST00000006898.3
ENSMUST00000110382.2
Gmnn

geminin

chr11_-_77894096 7.875 ENSMUST00000017597.4
Pipox
pipecolic acid oxidase
chr1_-_192771060 7.755 ENSMUST00000128619.1
ENSMUST00000044190.5
Hhat

hedgehog acyltransferase

chr4_+_59581563 7.724 ENSMUST00000030078.5
Hsdl2
hydroxysteroid dehydrogenase like 2
chr4_+_59581645 7.483 ENSMUST00000107528.1
Hsdl2
hydroxysteroid dehydrogenase like 2
chr14_+_65805832 7.253 ENSMUST00000022612.3
Pbk
PDZ binding kinase
chr15_-_10713537 7.225 ENSMUST00000090339.3
Rai14
retinoic acid induced 14
chr6_+_48841476 7.159 ENSMUST00000101426.4
Tmem176a
transmembrane protein 176A
chr2_-_91931696 7.130 ENSMUST00000090602.5
Mdk
midkine
chr2_+_118598209 7.084 ENSMUST00000038341.7
Bub1b
budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)
chr2_-_91931774 7.071 ENSMUST00000069423.6
Mdk
midkine
chr2_-_91931675 7.046 ENSMUST00000111309.1
Mdk
midkine
chr1_+_191821444 7.008 ENSMUST00000027931.7
Nek2
NIMA (never in mitosis gene a)-related expressed kinase 2
chr6_+_48841633 7.001 ENSMUST00000168406.1
Tmem176a
transmembrane protein 176A
chr7_-_132813528 6.892 ENSMUST00000097999.2
Fam53b
family with sequence similarity 53, member B
chr8_+_88521344 6.837 ENSMUST00000034086.5
Nkd1
naked cuticle 1 homolog (Drosophila)
chr10_-_88146867 6.820 ENSMUST00000164121.1
ENSMUST00000164803.1
ENSMUST00000168163.1
ENSMUST00000048518.9
Parpbp



PARP1 binding protein



chr14_+_46832127 6.758 ENSMUST00000068532.8
Cgrrf1
cell growth regulator with ring finger domain 1
chr2_+_164769892 6.639 ENSMUST00000088248.6
ENSMUST00000001439.6
Ube2c

ubiquitin-conjugating enzyme E2C

chr15_+_79028212 6.618 ENSMUST00000180086.1
H1f0
H1 histone family, member 0
chr3_+_88081997 6.430 ENSMUST00000071812.5
Iqgap3
IQ motif containing GTPase activating protein 3
chr18_-_74207771 6.213 ENSMUST00000040188.8
ENSMUST00000177604.1
Ska1

spindle and kinetochore associated complex subunit 1

chr6_-_95718800 6.086 ENSMUST00000079847.5
Suclg2
succinate-Coenzyme A ligase, GDP-forming, beta subunit
chr19_+_46707443 6.013 ENSMUST00000003655.7
As3mt
arsenic (+3 oxidation state) methyltransferase
chr17_+_56303321 5.973 ENSMUST00000001258.8
Uhrf1
ubiquitin-like, containing PHD and RING finger domains, 1
chr7_-_132813095 5.942 ENSMUST00000106165.1
Fam53b
family with sequence similarity 53, member B
chr1_-_133424377 5.870 ENSMUST00000153799.1
Sox13
SRY-box containing gene 13
chr11_-_106272927 5.694 ENSMUST00000021052.9
Smarcd2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
chr14_+_31217850 5.676 ENSMUST00000090180.2
Sema3g
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
chr3_+_94342092 5.662 ENSMUST00000029794.5
Them5
thioesterase superfamily member 5
chr17_+_56303396 5.552 ENSMUST00000113038.1
Uhrf1
ubiquitin-like, containing PHD and RING finger domains, 1
chr17_-_56830916 5.469 ENSMUST00000002444.7
ENSMUST00000086801.5
Rfx2

regulatory factor X, 2 (influences HLA class II expression)

chr19_-_8929323 5.425 ENSMUST00000096242.3
Rom1
rod outer segment membrane protein 1
chr6_+_124830217 5.297 ENSMUST00000131847.1
ENSMUST00000151674.1
Cdca3

cell division cycle associated 3

chr1_+_136467958 5.006 ENSMUST00000047817.6
Kif14
kinesin family member 14
chr4_-_41697040 4.971 ENSMUST00000102962.3
ENSMUST00000084701.5
Cntfr

ciliary neurotrophic factor receptor

chr4_+_110397661 4.857 ENSMUST00000106589.2
ENSMUST00000106587.2
ENSMUST00000106591.1
ENSMUST00000106592.1
Agbl4



ATP/GTP binding protein-like 4



chr2_+_154436437 4.782 ENSMUST00000109725.1
ENSMUST00000099178.3
ENSMUST00000045270.8
ENSMUST00000109724.1
Cbfa2t2



core-binding factor, runt domain, alpha subunit 2, translocated to, 2 (human)



chr11_+_117331719 4.755 ENSMUST00000100193.1
Sept9
septin 9
chr19_+_6975048 4.712 ENSMUST00000070850.6
Ppp1r14b
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr4_+_41760454 4.672 ENSMUST00000108040.1
Il11ra1
interleukin 11 receptor, alpha chain 1
chr3_-_100969644 4.627 ENSMUST00000076941.5
Ttf2
transcription termination factor, RNA polymerase II
chr4_+_11156411 4.620 ENSMUST00000029865.3
Trp53inp1
transformation related protein 53 inducible nuclear protein 1
chr5_-_30105359 4.619 ENSMUST00000127749.3
3110082J24Rik
RIKEN cDNA 3110082J24 gene
chr4_+_110397764 4.503 ENSMUST00000097920.2
ENSMUST00000080744.6
Agbl4

ATP/GTP binding protein-like 4

chr1_-_170306332 4.487 ENSMUST00000179801.1
Gm7694
predicted gene 7694
chr10_+_77581720 4.473 ENSMUST00000009435.5
Pttg1ip
pituitary tumor-transforming 1 interacting protein
chr14_+_55853997 4.469 ENSMUST00000100529.3
Nynrin
NYN domain and retroviral integrase containing
chr4_+_97777606 4.439 ENSMUST00000075448.6
ENSMUST00000092532.6
Nfia

nuclear factor I/A

chr7_-_48881596 4.360 ENSMUST00000119223.1
E2f8
E2F transcription factor 8
chr1_-_172027269 4.236 ENSMUST00000027837.6
ENSMUST00000111264.1
Vangl2

vang-like 2 (van gogh, Drosophila)

chr9_+_119402444 4.224 ENSMUST00000035093.8
ENSMUST00000165044.1
Acvr2b

activin receptor IIB

chr17_+_57249450 4.213 ENSMUST00000019631.9
Trip10
thyroid hormone receptor interactor 10
chr1_+_132316112 4.157 ENSMUST00000082125.5
ENSMUST00000072177.7
Nuak2

NUAK family, SNF1-like kinase, 2

chr10_+_93641041 4.148 ENSMUST00000020204.4
Ntn4
netrin 4
chr4_+_97777780 4.107 ENSMUST00000107062.2
ENSMUST00000052018.5
ENSMUST00000107057.1
Nfia


nuclear factor I/A


chr13_-_59675754 4.047 ENSMUST00000022039.5
ENSMUST00000095739.2
Golm1

golgi membrane protein 1

chr1_-_163289214 4.020 ENSMUST00000183691.1
Prrx1
paired related homeobox 1
chr10_+_77581774 3.935 ENSMUST00000162429.1
Pttg1ip
pituitary tumor-transforming 1 interacting protein
chr7_+_27258725 3.890 ENSMUST00000079258.6
Numbl
numb-like
chr3_+_76075583 3.877 ENSMUST00000160261.1
Fstl5
follistatin-like 5
chr7_+_31059342 3.861 ENSMUST00000039775.7
Lgi4
leucine-rich repeat LGI family, member 4
chr11_-_118909487 3.846 ENSMUST00000117731.1
ENSMUST00000106278.2
ENSMUST00000120061.1
ENSMUST00000017576.4
Rbfox3



RNA binding protein, fox-1 homolog (C. elegans) 3



chr8_+_70282978 3.792 ENSMUST00000110124.2
Homer3
homer homolog 3 (Drosophila)
chr5_+_53590453 3.769 ENSMUST00000113865.1
Rbpj
recombination signal binding protein for immunoglobulin kappa J region
chr10_+_128790903 3.764 ENSMUST00000026411.6
Mmp19
matrix metallopeptidase 19
chr1_-_120120937 3.764 ENSMUST00000151708.1
Dbi
diazepam binding inhibitor
chr14_+_55854115 3.761 ENSMUST00000168479.1
Nynrin
NYN domain and retroviral integrase containing
chr7_+_82611777 3.721 ENSMUST00000172784.1
Adamtsl3
ADAMTS-like 3
chr7_+_45639964 3.688 ENSMUST00000148532.1
Mamstr
MEF2 activating motif and SAP domain containing transcriptional regulator
chr2_+_174415804 3.655 ENSMUST00000109075.1
ENSMUST00000016397.6
Nelfcd

negative elongation factor complex member C/D, Th1l

chr1_-_44101982 3.583 ENSMUST00000127923.1
Tex30
testis expressed 30
chr1_-_20820213 3.561 ENSMUST00000053266.9
Mcm3
minichromosome maintenance deficient 3 (S. cerevisiae)
chr15_-_76009440 3.498 ENSMUST00000170153.1
Fam83h
family with sequence similarity 83, member H
chr6_-_5256226 3.444 ENSMUST00000125686.1
ENSMUST00000031773.2
Pon3

paraoxonase 3

chr2_+_165655237 3.434 ENSMUST00000063433.7
Eya2
eyes absent 2 homolog (Drosophila)
chr1_-_172027251 3.408 ENSMUST00000138714.1
Vangl2
vang-like 2 (van gogh, Drosophila)
chr10_-_79984227 3.404 ENSMUST00000052885.7
Tmem259
transmembrane protein 259
chr2_+_158794807 3.400 ENSMUST00000029186.7
ENSMUST00000109478.2
ENSMUST00000156893.1
Dhx35


DEAH (Asp-Glu-Ala-His) box polypeptide 35


chr9_-_42399709 3.383 ENSMUST00000160940.1
Tecta
tectorin alpha
chr10_-_127288999 3.341 ENSMUST00000119078.1
Mbd6
methyl-CpG binding domain protein 6
chr9_-_42399915 3.321 ENSMUST00000042190.7
Tecta
tectorin alpha
chr12_-_54999102 3.311 ENSMUST00000173529.1
Baz1a
bromodomain adjacent to zinc finger domain 1A
chr8_-_84662841 3.298 ENSMUST00000060427.4
Ier2
immediate early response 2
chr11_-_69413675 3.203 ENSMUST00000094077.4
Kdm6b
KDM1 lysine (K)-specific demethylase 6B
chr10_-_80399478 3.181 ENSMUST00000092295.3
ENSMUST00000105349.1
Mbd3

methyl-CpG binding domain protein 3

chr9_+_118506226 3.162 ENSMUST00000084820.4
Golga4
golgi autoantigen, golgin subfamily a, 4
chr2_-_91950386 3.157 ENSMUST00000111303.1
Dgkz
diacylglycerol kinase zeta
chr1_-_119648903 3.123 ENSMUST00000163147.1
ENSMUST00000052404.6
ENSMUST00000027632.7
Epb4.1l5


erythrocyte protein band 4.1-like 5


chr1_-_44101661 3.110 ENSMUST00000152239.1
Tex30
testis expressed 30
chr1_-_172219715 3.089 ENSMUST00000170700.1
ENSMUST00000003554.4
Casq1

calsequestrin 1

chr9_+_107576915 3.077 ENSMUST00000112387.2
ENSMUST00000123005.1
ENSMUST00000010195.7
ENSMUST00000144392.1
Hyal1



hyaluronoglucosaminidase 1



chr1_-_9700209 3.053 ENSMUST00000088658.4
Mybl1
myeloblastosis oncogene-like 1
chr7_-_18616498 3.041 ENSMUST00000057810.6
Psg23
pregnancy-specific glycoprotein 23
chr11_-_100850724 3.027 ENSMUST00000004143.2
Stat5b
signal transducer and activator of transcription 5B
chr1_-_44102362 3.016 ENSMUST00000147571.1
ENSMUST00000027215.5
ENSMUST00000147661.1
Tex30


testis expressed 30


chr3_-_89418287 2.989 ENSMUST00000029679.3
Cks1b
CDC28 protein kinase 1b
chr1_-_44102433 2.975 ENSMUST00000129702.1
ENSMUST00000149502.1
ENSMUST00000156392.1
ENSMUST00000150911.1
Tex30



testis expressed 30



chr1_-_44102414 2.974 ENSMUST00000143327.1
ENSMUST00000133677.1
Tex30

testis expressed 30

chr4_+_131873608 2.969 ENSMUST00000053819.3
Srsf4
serine/arginine-rich splicing factor 4
chr12_+_3954943 2.925 ENSMUST00000020990.5
Pomc
pro-opiomelanocortin-alpha
chr7_+_44465391 2.914 ENSMUST00000035929.4
ENSMUST00000146128.1
Aspdh

aspartate dehydrogenase domain containing

chr14_+_75455957 2.912 ENSMUST00000164848.1
Siah3
seven in absentia homolog 3 (Drosophila)
chr19_-_43912392 2.908 ENSMUST00000026209.4
Dnmbp
dynamin binding protein
chr17_-_31277327 2.878 ENSMUST00000024832.7
Rsph1
radial spoke head 1 homolog (Chlamydomonas)
chr19_+_8929628 2.848 ENSMUST00000096241.4
Eml3
echinoderm microtubule associated protein like 3
chr8_-_123318553 2.819 ENSMUST00000118395.1
ENSMUST00000035495.8
Fanca

Fanconi anemia, complementation group A

chr7_+_43444104 2.817 ENSMUST00000004729.3
Etfb
electron transferring flavoprotein, beta polypeptide
chr12_+_17690793 2.810 ENSMUST00000071858.3
Hpcal1
hippocalcin-like 1
chr17_+_47672720 2.793 ENSMUST00000152724.1
Usp49
ubiquitin specific peptidase 49
chr10_-_13324250 2.741 ENSMUST00000105543.1
Phactr2
phosphatase and actin regulator 2
chr5_+_36484578 2.738 ENSMUST00000060100.1
Ccdc96
coiled-coil domain containing 96
chr4_+_118428078 2.700 ENSMUST00000006557.6
ENSMUST00000167636.1
ENSMUST00000102673.4
Elovl1


elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1


chr9_-_124424154 2.692 ENSMUST00000180270.1
Ppp2r3d
protein phosphatase 2 (formerly 2A), regulatory subunit B'', delta
chr10_-_13324160 2.683 ENSMUST00000105545.4
Phactr2
phosphatase and actin regulator 2
chrX_+_35888808 2.635 ENSMUST00000033419.6
Dock11
dedicator of cytokinesis 11
chr10_-_80399389 2.623 ENSMUST00000105348.1
Mbd3
methyl-CpG binding domain protein 3
chr15_-_89425856 2.585 ENSMUST00000109313.2
Cpt1b
carnitine palmitoyltransferase 1b, muscle
chr6_-_88875035 2.556 ENSMUST00000145944.1
Podxl2
podocalyxin-like 2
chr11_-_54962903 2.547 ENSMUST00000108885.1
ENSMUST00000102730.2
ENSMUST00000018482.6
ENSMUST00000108886.1
ENSMUST00000102731.1
Tnip1




TNFAIP3 interacting protein 1




chr2_-_25356319 2.524 ENSMUST00000028332.7
Dpp7
dipeptidylpeptidase 7
chr1_+_131527901 2.510 ENSMUST00000068613.4
Fam72a
family with sequence similarity 72, member A
chr3_+_137864573 2.499 ENSMUST00000174561.1
ENSMUST00000173790.1
H2afz

H2A histone family, member Z

chr2_-_26237368 2.485 ENSMUST00000036187.8
Qsox2
quiescin Q6 sulfhydryl oxidase 2
chr11_-_69801716 2.391 ENSMUST00000011285.4
ENSMUST00000102585.1
Fgf11

fibroblast growth factor 11

chr10_+_128303322 2.380 ENSMUST00000005825.6
Pan2
PAN2 polyA specific ribonuclease subunit homolog (S. cerevisiae)
chr10_-_79983970 2.380 ENSMUST00000124536.1
Tmem259
transmembrane protein 259
chr11_-_69900949 2.362 ENSMUST00000102580.3
2810408A11Rik
RIKEN cDNA 2810408A11 gene
chr17_-_73950172 2.349 ENSMUST00000024866.4
Xdh
xanthine dehydrogenase
chr11_+_69991633 2.329 ENSMUST00000108592.1
Gabarap
gamma-aminobutyric acid receptor associated protein
chr3_+_95164306 2.328 ENSMUST00000107217.1
ENSMUST00000168321.1
Sema6c

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C

chr11_+_101442440 2.304 ENSMUST00000107249.1
Rpl27
ribosomal protein L27
chr10_+_88147061 2.303 ENSMUST00000169309.1
Nup37
nucleoporin 37
chr3_+_95124476 2.295 ENSMUST00000131597.1
ENSMUST00000005769.6
ENSMUST00000107227.1
Tmod4


tropomodulin 4


chr2_-_158028423 2.279 ENSMUST00000029179.4
Tti1
TELO2 interacting protein 1
chr13_-_55571118 2.237 ENSMUST00000021957.6
Fam193b
family with sequence similarity 193, member B
chr17_+_27029259 2.217 ENSMUST00000053683.6
Ggnbp1
gametogenetin binding protein 1
chr10_-_80102653 2.200 ENSMUST00000042771.7
Sbno2
strawberry notch homolog 2 (Drosophila)
chr1_+_72824482 2.191 ENSMUST00000047328.4
Igfbp2
insulin-like growth factor binding protein 2
chr11_+_23666479 2.188 ENSMUST00000143117.1
Pus10
pseudouridylate synthase 10
chr4_+_133176336 2.144 ENSMUST00000105912.1
Wasf2
WAS protein family, member 2
chr2_-_160872829 2.139 ENSMUST00000176141.1
Zhx3
zinc fingers and homeoboxes 3
chr17_-_56005566 2.116 ENSMUST00000043785.6
Stap2
signal transducing adaptor family member 2
chr19_+_38395980 2.115 ENSMUST00000054098.2
Slc35g1
solute carrier family 35, member G1
chr17_-_32800938 2.107 ENSMUST00000080905.6
Zfp811
zinc finger protein 811
chr7_-_126800036 2.071 ENSMUST00000133514.1
ENSMUST00000151137.1
Aldoa

aldolase A, fructose-bisphosphate

chr8_-_4216912 2.062 ENSMUST00000177491.1
BC068157
cDNA sequence BC068157
chr11_-_100759942 2.045 ENSMUST00000107363.2
Kcnh4
potassium voltage-gated channel, subfamily H (eag-related), member 4
chr11_+_101442298 2.040 ENSMUST00000077856.6
Rpl27
ribosomal protein L27
chr18_-_88927447 2.029 ENSMUST00000147313.1
Socs6
suppressor of cytokine signaling 6
chr18_-_36744518 2.026 ENSMUST00000014438.4
Ndufa2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2
chr8_-_120228221 2.007 ENSMUST00000183235.1
A330074K22Rik
RIKEN cDNA A330074K22 gene
chr9_-_65885024 2.005 ENSMUST00000122410.1
ENSMUST00000117083.1
Trip4

thyroid hormone receptor interactor 4

chr7_-_126800354 1.962 ENSMUST00000106348.1
Aldoa
aldolase A, fructose-bisphosphate
chr2_-_84743655 1.958 ENSMUST00000181711.1
Gm19426
predicted gene, 19426
chr13_+_44729535 1.956 ENSMUST00000174068.1
Jarid2
jumonji, AT rich interactive domain 2
chr4_+_118429701 1.933 ENSMUST00000067896.3
Elovl1
elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1
chr7_-_23947237 1.921 ENSMUST00000086013.2
Gm10175
predicted gene 10175
chrX_+_10485121 1.900 ENSMUST00000076354.6
ENSMUST00000115526.1
Tspan7

tetraspanin 7

chr3_-_84582476 1.893 ENSMUST00000107687.2
ENSMUST00000098990.3
Arfip1

ADP-ribosylation factor interacting protein 1

chr2_-_30830333 1.884 ENSMUST00000041726.3
Asb6
ankyrin repeat and SOCS box-containing 6
chr4_+_129461581 1.881 ENSMUST00000048162.8
ENSMUST00000138013.1
Bsdc1

BSD domain containing 1

chr6_+_71282280 1.875 ENSMUST00000080949.7
Krcc1
lysine-rich coiled-coil 1
chr17_-_35132050 1.867 ENSMUST00000025249.6
Apom
apolipoprotein M
chr7_-_44548733 1.858 ENSMUST00000145956.1
ENSMUST00000049343.8
Pold1

polymerase (DNA directed), delta 1, catalytic subunit

chr15_-_89425795 1.855 ENSMUST00000168376.1
Cpt1b
carnitine palmitoyltransferase 1b, muscle
chr17_-_29007925 1.852 ENSMUST00000009138.5
ENSMUST00000119274.1
Stk38

serine/threonine kinase 38

chr2_+_126556128 1.849 ENSMUST00000141482.2
Slc27a2
solute carrier family 27 (fatty acid transporter), member 2
chr8_+_79028317 1.833 ENSMUST00000087927.4
ENSMUST00000098614.2
Zfp827

zinc finger protein 827

chr15_-_102189032 1.814 ENSMUST00000023805.1
Csad
cysteine sulfinic acid decarboxylase
chrX_+_9885622 1.805 ENSMUST00000067529.2
ENSMUST00000086165.3
Sytl5

synaptotagmin-like 5

chr2_+_103970115 1.798 ENSMUST00000111143.1
ENSMUST00000138815.1
Lmo2

LIM domain only 2

chr2_+_163658370 1.777 ENSMUST00000164399.1
ENSMUST00000064703.6
ENSMUST00000099105.2
ENSMUST00000152418.1
ENSMUST00000126182.1
ENSMUST00000131228.1
Pkig





protein kinase inhibitor, gamma





chr11_-_69900886 1.774 ENSMUST00000108621.2
ENSMUST00000100969.2
2810408A11Rik

RIKEN cDNA 2810408A11 gene

chr13_+_44729794 1.756 ENSMUST00000172830.1
Jarid2
jumonji, AT rich interactive domain 2
chr17_-_57247632 1.721 ENSMUST00000005975.6
Gpr108
G protein-coupled receptor 108
chr9_-_106158109 1.713 ENSMUST00000159809.1
ENSMUST00000162562.1
ENSMUST00000036382.6
ENSMUST00000112543.2
Glyctk



glycerate kinase



chr6_+_29694204 1.709 ENSMUST00000046750.7
ENSMUST00000115250.3
Tspan33

tetraspanin 33

chr11_-_69900930 1.686 ENSMUST00000018714.6
ENSMUST00000128046.1
2810408A11Rik

RIKEN cDNA 2810408A11 gene

chr11_+_23666007 1.673 ENSMUST00000058163.4
Pus10
pseudouridylate synthase 10
chr11_-_70656467 1.667 ENSMUST00000131642.1
Gm12319
predicted gene 12319
chr2_+_103970221 1.656 ENSMUST00000111140.2
ENSMUST00000111139.2
Lmo2

LIM domain only 2

chr5_-_134314378 1.650 ENSMUST00000174867.1
Gtf2i
general transcription factor II I
chr17_-_87265866 1.629 ENSMUST00000145895.1
ENSMUST00000129616.1
ENSMUST00000155904.1
ENSMUST00000151155.1
ENSMUST00000144236.1
ENSMUST00000024963.3
Mcfd2





multiple coagulation factor deficiency 2





chr1_+_171329569 1.613 ENSMUST00000142063.1
ENSMUST00000129116.1
Dedd

death effector domain-containing

chr15_+_100304782 1.613 ENSMUST00000067752.3
Mettl7a1
methyltransferase like 7A1
chr18_-_12236301 1.611 ENSMUST00000025279.5
Npc1
Niemann Pick type C1
chr3_-_79628660 1.607 ENSMUST00000120992.1
Etfdh
electron transferring flavoprotein, dehydrogenase

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
7.1 21.2 GO:0030421 defecation(GO:0030421)
3.3 23.2 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
2.6 7.9 GO:0006553 lysine metabolic process(GO:0006553)
2.6 12.9 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151)
2.5 7.6 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
2.5 12.4 GO:0035262 gonad morphogenesis(GO:0035262)
2.4 7.1 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
2.3 9.4 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
2.0 18.3 GO:0048251 elastic fiber assembly(GO:0048251)
1.8 7.0 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
1.7 5.0 GO:0021698 cerebellar cortex structural organization(GO:0021698)
1.7 5.0 GO:0003360 brainstem development(GO:0003360)
1.5 4.6 GO:1904760 myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760)
1.5 4.4 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
1.5 7.3 GO:0010993 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
1.3 3.9 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
1.3 3.8 GO:0072554 arterial endothelial cell fate commitment(GO:0060844) blood vessel endothelial cell fate commitment(GO:0060846) endothelial cell fate specification(GO:0060847) Notch signaling pathway involved in arterial endothelial cell fate commitment(GO:0060853) blood vessel lumenization(GO:0072554) blood vessel endothelial cell fate specification(GO:0097101) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) positive regulation of heart induction(GO:1901321) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
1.0 3.1 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
1.0 8.2 GO:0015074 DNA integration(GO:0015074)
1.0 3.1 GO:0036118 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
1.0 9.2 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
1.0 3.0 GO:0046544 regulation of natural killer cell proliferation(GO:0032817) positive regulation of natural killer cell proliferation(GO:0032819) development of secondary male sexual characteristics(GO:0046544)
1.0 2.9 GO:0035934 corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.9 7.4 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.9 4.5 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.9 11.5 GO:0090308 regulation of methylation-dependent chromatin silencing(GO:0090308)
0.8 4.1 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.7 4.4 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.7 2.9 GO:0006742 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.7 6.1 GO:0006105 succinyl-CoA metabolic process(GO:0006104) succinate metabolic process(GO:0006105)
0.7 6.0 GO:0042538 hyperosmotic salinity response(GO:0042538)
0.6 6.4 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.6 2.5 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.6 1.9 GO:0050748 negative regulation of lipoprotein metabolic process(GO:0050748)
0.6 1.9 GO:0045004 DNA replication proofreading(GO:0045004)
0.6 1.8 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.6 1.8 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160)
0.6 1.8 GO:0019530 taurine metabolic process(GO:0019530)
0.6 2.9 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.6 1.1 GO:0072053 renal inner medulla development(GO:0072053) renal outer medulla development(GO:0072054)
0.6 2.8 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.6 8.8 GO:0072189 ureter development(GO:0072189)
0.5 2.2 GO:0071105 response to interleukin-11(GO:0071105)
0.5 5.9 GO:0046643 regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643)
0.5 7.9 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.5 1.6 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.5 5.1 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.5 6.0 GO:0009404 toxin metabolic process(GO:0009404)
0.5 8.4 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.5 5.3 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.5 5.7 GO:0035336 long-chain fatty-acyl-CoA metabolic process(GO:0035336)
0.4 3.4 GO:0016576 histone dephosphorylation(GO:0016576)
0.4 2.1 GO:1990034 calcium ion export from cell(GO:1990034)
0.4 4.6 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.4 1.3 GO:0006578 amino-acid betaine biosynthetic process(GO:0006578)
0.4 5.3 GO:0001675 acrosome assembly(GO:0001675)
0.4 2.8 GO:0043383 negative T cell selection(GO:0043383) negative thymic T cell selection(GO:0045060)
0.4 4.0 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.4 2.8 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.4 3.2 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.4 6.3 GO:0006337 nucleosome disassembly(GO:0006337)
0.4 1.2 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.4 1.2 GO:0045014 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014) detection of glucose(GO:0051594)
0.4 2.3 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.4 4.1 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.4 1.9 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.4 4.2 GO:0060836 lymphatic endothelial cell differentiation(GO:0060836)
0.4 2.1 GO:0072081 proximal/distal pattern formation involved in nephron development(GO:0072047) specification of nephron tubule identity(GO:0072081) specification of loop of Henle identity(GO:0072086)
0.3 1.0 GO:0090118 receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118)
0.3 4.4 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.3 5.4 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.3 3.7 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.3 2.7 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.3 2.5 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.3 1.9 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.3 13.0 GO:0035411 catenin import into nucleus(GO:0035411)
0.3 5.3 GO:1904294 positive regulation of ERAD pathway(GO:1904294)
0.3 4.0 GO:0048664 neuron fate determination(GO:0048664)
0.3 3.1 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.3 4.6 GO:0006353 DNA-templated transcription, termination(GO:0006353)
0.3 1.5 GO:1990839 response to endothelin(GO:1990839)
0.3 16.4 GO:0070303 negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303)
0.3 0.6 GO:0060686 regulation of prostatic bud formation(GO:0060685) negative regulation of prostatic bud formation(GO:0060686)
0.3 1.2 GO:0002484 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway(GO:0002484) antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent(GO:0002485)
0.3 2.0 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.3 3.5 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.3 3.2 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.3 0.9 GO:0032847 positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of cellular pH reduction(GO:0032847) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.3 2.5 GO:0031547 brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
0.3 0.6 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.3 4.4 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291)
0.3 7.8 GO:0018345 protein palmitoylation(GO:0018345)
0.3 0.8 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.3 1.5 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.3 2.8 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.2 1.0 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726)
0.2 0.5 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.2 3.8 GO:0030574 collagen catabolic process(GO:0030574)
0.2 3.5 GO:0046697 decidualization(GO:0046697)
0.2 0.7 GO:1901052 sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053)
0.2 1.4 GO:0032490 detection of molecule of bacterial origin(GO:0032490)
0.2 3.8 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.2 1.3 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.2 1.5 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.2 1.0 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.2 4.8 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.2 1.1 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.2 8.1 GO:1902476 chloride transmembrane transport(GO:1902476)
0.2 0.9 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.2 0.6 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.2 1.6 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.2 0.7 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.2 1.6 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.2 0.5 GO:0070459 prolactin secretion(GO:0070459)
0.2 0.7 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.2 1.8 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.2 2.6 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.2 3.5 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.2 0.5 GO:0045056 transcytosis(GO:0045056)
0.2 2.0 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.2 0.2 GO:0060700 regulation of ribonuclease activity(GO:0060700)
0.2 0.5 GO:1905076 interleukin-17 secretion(GO:0072615) regulation of interleukin-17 secretion(GO:1905076)
0.1 0.7 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.1 0.4 GO:0003195 tricuspid valve formation(GO:0003195) right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.1 1.5 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.1 1.7 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.1 5.0 GO:0030517 negative regulation of axon extension(GO:0030517)
0.1 1.0 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1 8.6 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.1 4.2 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.1 0.3 GO:0035964 COPI-coated vesicle budding(GO:0035964)
0.1 2.1 GO:0072673 lamellipodium morphogenesis(GO:0072673)
0.1 1.2 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 0.8 GO:0090383 phagosome acidification(GO:0090383)
0.1 1.2 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.1 1.4 GO:0042098 T cell proliferation(GO:0042098)
0.1 1.2 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.1 1.1 GO:0042435 indole-containing compound biosynthetic process(GO:0042435)
0.1 0.6 GO:0060065 uterus development(GO:0060065)
0.1 1.0 GO:0031053 primary miRNA processing(GO:0031053)
0.1 2.5 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.1 0.4 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.1 3.9 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.1 1.5 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.1 1.8 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.1 4.4 GO:0015909 long-chain fatty acid transport(GO:0015909)
0.1 0.8 GO:0015879 carnitine transport(GO:0015879)
0.1 2.1 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.1 1.1 GO:0043649 dicarboxylic acid catabolic process(GO:0043649)
0.1 1.5 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 1.2 GO:0060539 diaphragm development(GO:0060539)
0.1 1.0 GO:1903961 positive regulation of anion transmembrane transport(GO:1903961)
0.1 3.0 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.1 0.2 GO:1901896 positive regulation of calcium-transporting ATPase activity(GO:1901896)
0.1 0.4 GO:0006788 heme oxidation(GO:0006788)
0.1 0.5 GO:0018002 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.1 1.5 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.1 0.7 GO:0030224 monocyte differentiation(GO:0030224)
0.1 0.4 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.1 3.6 GO:0006270 DNA replication initiation(GO:0006270)
0.1 3.0 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.1 0.4 GO:0034116 positive regulation of heterotypic cell-cell adhesion(GO:0034116)
0.1 0.6 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 3.9 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1 0.4 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.1 1.9 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.1 2.6 GO:0045773 positive regulation of axon extension(GO:0045773)
0.1 1.1 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 1.5 GO:0016311 dephosphorylation(GO:0016311)
0.1 0.8 GO:0032620 interleukin-17 production(GO:0032620)
0.1 1.9 GO:0030520 intracellular estrogen receptor signaling pathway(GO:0030520)
0.1 1.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 2.3 GO:0007411 axon guidance(GO:0007411)
0.1 2.8 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 1.1 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.1 1.2 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 2.0 GO:0000266 mitochondrial fission(GO:0000266)
0.1 2.9 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.1 2.8 GO:0044380 protein localization to cytoskeleton(GO:0044380)
0.1 0.8 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.1 0.5 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 1.3 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.1 0.6 GO:0046485 ether lipid metabolic process(GO:0046485)
0.1 1.4 GO:0009649 entrainment of circadian clock(GO:0009649)
0.1 0.4 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.1 0.6 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.1 0.4 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.1 7.0 GO:0030308 negative regulation of cell growth(GO:0030308)
0.1 0.4 GO:1902741 type I interferon secretion(GO:0072641) interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
0.1 0.7 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.1 0.6 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.1 1.1 GO:0046033 AMP metabolic process(GO:0046033)
0.1 3.2 GO:0071774 response to fibroblast growth factor(GO:0071774)
0.1 0.3 GO:1903772 regulation of viral budding via host ESCRT complex(GO:1903772)
0.1 1.3 GO:0033622 integrin activation(GO:0033622)
0.0 0.4 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.0 0.1 GO:0035963 response to interleukin-13(GO:0035962) cellular response to interleukin-13(GO:0035963)
0.0 0.9 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.0 0.7 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 2.7 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.0 0.5 GO:0061436 establishment of skin barrier(GO:0061436)
0.0 0.3 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.0 0.3 GO:0016322 neuron remodeling(GO:0016322)
0.0 1.1 GO:0048016 inositol phosphate-mediated signaling(GO:0048016)
0.0 1.2 GO:1903747 regulation of protein targeting to mitochondrion(GO:1903214) regulation of establishment of protein localization to mitochondrion(GO:1903747)
0.0 0.4 GO:0007131 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.0 0.2 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.0 0.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 1.1 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 2.3 GO:0032006 regulation of TOR signaling(GO:0032006)
0.0 0.7 GO:0042246 tissue regeneration(GO:0042246)
0.0 1.9 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 2.4 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0 1.0 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 2.6 GO:0051321 meiotic cell cycle(GO:0051321)
0.0 6.4 GO:0007059 chromosome segregation(GO:0007059)
0.0 0.3 GO:0051346 negative regulation of hydrolase activity(GO:0051346)
0.0 0.5 GO:0035066 positive regulation of histone acetylation(GO:0035066)
0.0 3.1 GO:0006997 nucleus organization(GO:0006997)
0.0 0.8 GO:0021795 cerebral cortex cell migration(GO:0021795)
0.0 5.2 GO:0051604 protein maturation(GO:0051604)
0.0 2.5 GO:0007605 sensory perception of sound(GO:0007605)
0.0 2.2 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0 0.4 GO:0006515 misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.0 0.0 GO:0003256 regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003256)
0.0 0.9 GO:0006505 GPI anchor metabolic process(GO:0006505) GPI anchor biosynthetic process(GO:0006506)
0.0 0.8 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.2 GO:2000671 regulation of motor neuron apoptotic process(GO:2000671)
0.0 0.7 GO:0015914 phospholipid transport(GO:0015914)
0.0 1.1 GO:0018022 peptidyl-lysine methylation(GO:0018022)
0.0 0.4 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 0.7 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.5 GO:0016574 histone ubiquitination(GO:0016574)
0.0 0.3 GO:0010824 regulation of centrosome duplication(GO:0010824)
0.0 0.4 GO:2000378 negative regulation of reactive oxygen species metabolic process(GO:2000378)
0.0 0.2 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 0.1 GO:0016575 histone deacetylation(GO:0016575)
0.0 7.6 GO:0000122 negative regulation of transcription from RNA polymerase II promoter(GO:0000122)
0.0 0.7 GO:0032543 mitochondrial translation(GO:0032543)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
6.1 18.3 GO:0071953 elastic fiber(GO:0071953)
1.9 7.6 GO:0060187 cell pole(GO:0060187)
1.7 5.0 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
1.2 4.8 GO:0032021 NELF complex(GO:0032021)
1.2 3.5 GO:0032588 trans-Golgi network membrane(GO:0032588)
1.1 4.4 GO:0045251 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
1.0 13.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.8 3.3 GO:0008623 CHRAC(GO:0008623)
0.8 2.4 GO:0031251 PAN complex(GO:0031251)
0.8 4.7 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.8 3.1 GO:0014802 terminal cisterna(GO:0014802)
0.8 3.8 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.6 1.9 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.5 1.9 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.5 12.9 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.5 1.8 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.4 5.8 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.4 1.6 GO:0045098 type III intermediate filament(GO:0045098)
0.4 1.6 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.4 3.7 GO:0031080 nuclear pore outer ring(GO:0031080)
0.4 2.9 GO:0001520 outer dense fiber(GO:0001520)
0.4 2.5 GO:0001740 Barr body(GO:0001740)
0.3 3.8 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.3 4.8 GO:0031105 septin complex(GO:0031105)
0.3 6.3 GO:0016514 SWI/SNF complex(GO:0016514)
0.3 2.5 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.3 6.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.3 4.0 GO:0035686 sperm fibrous sheath(GO:0035686)
0.3 1.7 GO:0045178 basal part of cell(GO:0045178)
0.3 3.5 GO:0045095 keratin filament(GO:0045095)
0.3 6.6 GO:0005680 anaphase-promoting complex(GO:0005680)
0.3 14.1 GO:0000791 euchromatin(GO:0000791)
0.3 1.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.3 2.8 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.3 1.0 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.2 1.7 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.2 5.8 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.2 3.6 GO:0042555 MCM complex(GO:0042555)
0.2 0.7 GO:0055087 Ski complex(GO:0055087)
0.2 3.7 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.2 9.1 GO:0034707 chloride channel complex(GO:0034707)
0.2 1.6 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.2 1.0 GO:0034715 U7 snRNP(GO:0005683) pICln-Sm protein complex(GO:0034715)
0.2 1.8 GO:0061574 ASAP complex(GO:0061574)
0.2 3.3 GO:0010369 chromocenter(GO:0010369)
0.2 2.1 GO:0031209 SCAR complex(GO:0031209)
0.1 0.6 GO:0000438 core TFIIH complex portion of holo TFIIH complex(GO:0000438)
0.1 1.8 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 0.7 GO:1990130 Iml1 complex(GO:1990130)
0.1 2.6 GO:0005682 U5 snRNP(GO:0005682)
0.1 2.3 GO:0097225 sperm midpiece(GO:0097225)
0.1 1.2 GO:0031931 TORC1 complex(GO:0031931)
0.1 1.1 GO:0005721 pericentric heterochromatin(GO:0005721)
0.1 4.2 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 0.6 GO:0042825 TAP complex(GO:0042825)
0.1 7.0 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.1 2.3 GO:0005865 striated muscle thin filament(GO:0005865)
0.1 0.8 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 8.9 GO:0005814 centriole(GO:0005814)
0.1 4.2 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 0.7 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.1 0.4 GO:0005663 DNA replication factor C complex(GO:0005663)
0.1 0.5 GO:0033503 HULC complex(GO:0033503)
0.1 13.4 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 1.1 GO:1904115 axon cytoplasm(GO:1904115)
0.1 3.7 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 0.5 GO:0070578 RISC-loading complex(GO:0070578)
0.1 1.0 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 1.1 GO:0030018 Z disc(GO:0030018)
0.1 3.8 GO:0005871 kinesin complex(GO:0005871)
0.1 4.1 GO:0005811 lipid particle(GO:0005811)
0.1 1.4 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.1 5.8 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 0.4 GO:0042629 mast cell granule(GO:0042629)
0.1 0.3 GO:0016580 Sin3 complex(GO:0016580)
0.1 0.4 GO:0005638 lamin filament(GO:0005638)
0.0 2.0 GO:0001772 immunological synapse(GO:0001772)
0.0 3.6 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.2 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 1.6 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 1.1 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.6 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.3 GO:0070652 HAUS complex(GO:0070652)
0.0 2.9 GO:0005776 autophagosome(GO:0005776)
0.0 2.4 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.4 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 2.1 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.4 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 6.1 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.3 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.4 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 1.4 GO:1990204 oxidoreductase complex(GO:1990204)
0.0 2.0 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.4 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.3 GO:0000813 ESCRT I complex(GO:0000813)
0.0 2.5 GO:0031225 anchored component of membrane(GO:0031225)
0.0 2.7 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 0.9 GO:0016592 mediator complex(GO:0016592)
0.0 7.5 GO:0016607 nuclear speck(GO:0016607)
0.0 0.5 GO:0030914 STAGA complex(GO:0030914)
0.0 2.7 GO:0005681 spliceosomal complex(GO:0005681)
0.0 1.6 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.7 GO:0060077 inhibitory synapse(GO:0060077)
0.0 1.3 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 7.7 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.2 GO:0000139 Golgi membrane(GO:0000139)
0.0 1.3 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.0 2.0 GO:0030141 secretory granule(GO:0030141)
0.0 1.2 GO:0016605 PML body(GO:0016605)
0.0 1.3 GO:0005581 collagen trimer(GO:0005581)
0.0 0.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 5.0 GO:0000785 chromatin(GO:0000785)
0.0 0.9 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 1.8 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.4 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.2 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.6 GO:0005604 basement membrane(GO:0005604)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
4.3 12.9 GO:0030156 benzodiazepine receptor binding(GO:0030156)
2.9 11.5 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
2.0 6.1 GO:0004774 succinate-CoA ligase activity(GO:0004774)
2.0 7.9 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
1.3 6.4 GO:0032027 myosin light chain binding(GO:0032027)
1.2 4.7 GO:0004921 interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970)
1.0 3.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.9 4.4 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.9 3.5 GO:1990254 keratin filament binding(GO:1990254)
0.9 3.4 GO:0004064 arylesterase activity(GO:0004064)
0.8 2.5 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.7 3.0 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.7 4.0 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.7 2.6 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.6 2.5 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.6 2.3 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.5 8.8 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.5 4.2 GO:0034711 inhibin binding(GO:0034711)
0.5 4.1 GO:0043237 laminin-1 binding(GO:0043237)
0.5 3.2 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.4 1.8 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.4 6.8 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.4 4.6 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.4 2.5 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.4 6.6 GO:0003680 AT DNA binding(GO:0003680)
0.4 2.0 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.4 1.6 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.4 1.5 GO:0048408 epidermal growth factor binding(GO:0048408)
0.4 2.7 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.4 3.1 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.3 1.3 GO:0004111 creatine kinase activity(GO:0004111)
0.3 1.3 GO:0070991 medium-chain-acyl-CoA dehydrogenase activity(GO:0070991)
0.3 3.2 GO:0001727 lipid kinase activity(GO:0001727)
0.3 1.8 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.3 1.5 GO:0070404 NADH binding(GO:0070404)
0.3 14.6 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.3 5.1 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.3 1.1 GO:0004103 choline kinase activity(GO:0004103)
0.3 1.1 GO:1902379 chemoattractant activity involved in axon guidance(GO:1902379)
0.3 2.2 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.3 0.8 GO:0031779 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.3 0.8 GO:0004658 propionyl-CoA carboxylase activity(GO:0004658)
0.3 1.0 GO:0033883 pyridoxal phosphatase activity(GO:0033883)
0.3 2.3 GO:0005523 tropomyosin binding(GO:0005523)
0.3 4.8 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.2 1.5 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.2 7.8 GO:0016409 palmitoyltransferase activity(GO:0016409)
0.2 0.7 GO:0046997 sarcosine dehydrogenase activity(GO:0008480) oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.2 0.7 GO:0071723 lipopeptide binding(GO:0071723)
0.2 0.6 GO:0019966 interleukin-1 binding(GO:0019966)
0.2 0.9 GO:0031893 vasopressin receptor binding(GO:0031893)
0.2 3.0 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.2 1.9 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.2 0.8 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.2 3.8 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.2 2.5 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.2 6.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.2 1.1 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.2 1.1 GO:0042731 PH domain binding(GO:0042731)
0.2 1.5 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.2 0.7 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.2 1.8 GO:0031957 fatty acid transporter activity(GO:0015245) very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.2 2.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.2 1.8 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.2 2.9 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.2 2.3 GO:0050811 GABA receptor binding(GO:0050811)
0.2 4.0 GO:0071837 HMG box domain binding(GO:0071837)
0.2 2.0 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.2 0.6 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433) tapasin binding(GO:0046980)
0.2 4.1 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.2 0.6 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.1 1.6 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 0.4 GO:0019779 Atg12 activating enzyme activity(GO:0019778) Atg8 activating enzyme activity(GO:0019779)
0.1 0.4 GO:0008384 IkappaB kinase activity(GO:0008384)
0.1 1.5 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.1 4.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 3.0 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 13.6 GO:0008083 growth factor activity(GO:0008083)
0.1 10.7 GO:0070491 repressing transcription factor binding(GO:0070491)
0.1 0.8 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.1 1.2 GO:0015197 peptide transporter activity(GO:0015197)
0.1 9.1 GO:0005254 chloride channel activity(GO:0005254)
0.1 1.4 GO:0019215 intermediate filament binding(GO:0019215)
0.1 1.5 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.4 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 0.6 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 6.3 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.1 5.3 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 0.8 GO:0042609 CD4 receptor binding(GO:0042609)
0.1 1.2 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.1 0.4 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.1 0.5 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.1 1.0 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 4.5 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.1 1.0 GO:0001055 RNA polymerase II activity(GO:0001055)
0.1 3.5 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.1 0.9 GO:0003993 acid phosphatase activity(GO:0003993)
0.1 3.7 GO:0032452 histone demethylase activity(GO:0032452)
0.1 17.2 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 3.1 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 1.0 GO:0046977 TAP binding(GO:0046977)
0.1 2.5 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 0.6 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.1 0.6 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.1 1.3 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 2.3 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1 6.0 GO:0016209 antioxidant activity(GO:0016209)
0.1 12.1 GO:0003714 transcription corepressor activity(GO:0003714)
0.1 1.8 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 0.2 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.1 2.9 GO:0016504 peptidase activator activity(GO:0016504)
0.1 0.6 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 1.9 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.5 GO:0097322 7SK snRNA binding(GO:0097322)
0.1 0.7 GO:0004622 lysophospholipase activity(GO:0004622)
0.1 1.4 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.1 1.8 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 4.3 GO:0002039 p53 binding(GO:0002039)
0.1 1.1 GO:0030546 receptor activator activity(GO:0030546)
0.1 1.7 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.1 1.5 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.1 13.5 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.1 3.8 GO:0001076 transcription factor activity, RNA polymerase II transcription factor binding(GO:0001076)
0.1 1.1 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 7.8 GO:0004386 helicase activity(GO:0004386)
0.0 0.5 GO:0019865 immunoglobulin binding(GO:0019865)
0.0 0.4 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.2 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.0 0.4 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0 0.4 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 4.9 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 2.8 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 3.5 GO:0005178 integrin binding(GO:0005178)
0.0 0.7 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.3 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.0 1.8 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.0 2.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.8 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 6.9 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.9 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 1.1 GO:0019838 growth factor binding(GO:0019838)
0.0 0.4 GO:0070403 NAD+ binding(GO:0070403)
0.0 3.9 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 0.6 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.2 GO:0042301 phosphate ion binding(GO:0042301)
0.0 1.1 GO:0016278 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.0 4.8 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 11.2 GO:0043565 sequence-specific DNA binding(GO:0043565)
0.0 0.3 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.3 GO:0034061 DNA-directed DNA polymerase activity(GO:0003887) DNA polymerase activity(GO:0034061)
0.0 1.5 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.0 0.6 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 1.5 GO:0004519 endonuclease activity(GO:0004519)
0.0 2.0 GO:0019903 protein phosphatase binding(GO:0019903)
0.0 3.2 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.3 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 8.7 GO:0003677 DNA binding(GO:0003677)
0.0 3.6 GO:0045296 cadherin binding(GO:0045296)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 21.2 PID_INTEGRIN_A4B1_PATHWAY Alpha4 beta1 integrin signaling events
0.3 2.9 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.2 3.0 PID_IL5_PATHWAY IL5-mediated signaling events
0.2 6.4 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.2 10.6 PID_PS1_PATHWAY Presenilin action in Notch and Wnt signaling
0.2 25.3 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.2 2.2 PID_IL3_PATHWAY IL3-mediated signaling events
0.2 7.1 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.1 5.4 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 8.7 PID_PLK1_PATHWAY PLK1 signaling events
0.1 4.2 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.1 7.3 PID_RAC1_PATHWAY RAC1 signaling pathway
0.1 4.7 PID_BARD1_PATHWAY BARD1 signaling events
0.1 3.2 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.1 9.4 PID_HDAC_CLASSI_PATHWAY Signaling events mediated by HDAC Class I
0.1 2.9 PID_IL1_PATHWAY IL1-mediated signaling events
0.1 4.7 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.1 5.9 PID_E2F_PATHWAY E2F transcription factor network
0.1 1.3 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.1 2.0 PID_ALK1_PATHWAY ALK1 signaling events
0.0 0.8 PID_NECTIN_PATHWAY Nectin adhesion pathway
0.0 1.6 PID_BMP_PATHWAY BMP receptor signaling
0.0 1.3 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.9 PID_IL4_2PATHWAY IL4-mediated signaling events
0.0 1.3 NABA_COLLAGENS Genes encoding collagen proteins
0.0 0.4 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.0 0.7 PID_IL6_7_PATHWAY IL6-mediated signaling events
0.0 0.2 PID_LYMPH_ANGIOGENESIS_PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 2.4 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 2.7 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.4 PID_ATR_PATHWAY ATR signaling pathway
0.0 0.3 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.0 0.6 PID_P73PATHWAY p73 transcription factor network
0.0 0.5 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.4 NABA_PROTEOGLYCANS Genes encoding proteoglycans

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 20.7 REACTOME_APC_CDC20_MEDIATED_DEGRADATION_OF_NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.8 13.0 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.7 9.2 REACTOME_ASSOCIATION_OF_LICENSING_FACTORS_WITH_THE_PRE_REPLICATIVE_COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.6 2.9 REACTOME_ANDROGEN_BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.4 6.6 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.4 2.0 REACTOME_REGULATION_OF_KIT_SIGNALING Genes involved in Regulation of KIT signaling
0.3 2.5 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION_IN_TLR7_8_OR_9_SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.3 3.1 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.3 3.0 REACTOME_PROLACTIN_RECEPTOR_SIGNALING Genes involved in Prolactin receptor signaling
0.3 5.7 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.2 3.0 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.2 4.1 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.2 3.6 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.2 4.2 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL
0.2 1.9 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.2 4.4 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.1 3.2 REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1 2.2 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 2.8 REACTOME_FANCONI_ANEMIA_PATHWAY Genes involved in Fanconi Anemia pathway
0.1 8.6 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.1 2.0 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 3.7 REACTOME_TRANSPORT_OF_RIBONUCLEOPROTEINS_INTO_THE_HOST_NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.1 1.8 REACTOME_INTEGRATION_OF_PROVIRUS Genes involved in Integration of provirus
0.1 1.1 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.1 2.4 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 3.9 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 1.1 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 3.0 REACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.1 1.0 REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1 1.8 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 1.3 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.1 1.5 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.1 1.0 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 2.5 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.1 4.1 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.1 1.5 REACTOME_MICRORNA_MIRNA_BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.1 0.4 REACTOME_REPAIR_SYNTHESIS_FOR_GAP_FILLING_BY_DNA_POL_IN_TC_NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.1 0.5 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.1 5.0 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 0.6 REACTOME_ER_PHAGOSOME_PATHWAY Genes involved in ER-Phagosome pathway
0.0 3.0 REACTOME_SCFSKP2_MEDIATED_DEGRADATION_OF_P27_P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0 2.0 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.1 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.0 0.4 REACTOME_IRAK1_RECRUITS_IKK_COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 1.5 REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.6 REACTOME_MRNA_CAPPING Genes involved in mRNA Capping
0.0 4.0 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.0 2.6 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.9 REACTOME_PEROXISOMAL_LIPID_METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.9 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.8 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.3 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.7 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.4 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 1.0 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.3 REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 1.6 REACTOME_CELL_JUNCTION_ORGANIZATION Genes involved in Cell junction organization
0.0 0.1 REACTOME_CALNEXIN_CALRETICULIN_CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.6 REACTOME_HOST_INTERACTIONS_OF_HIV_FACTORS Genes involved in Host Interactions of HIV factors
0.0 2.4 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.2 REACTOME_JNK_C_JUN_KINASES_PHOSPHORYLATION_AND_ACTIVATION_MEDIATED_BY_ACTIVATED_HUMAN_TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.4 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis