Motif ID: Nr2e3
Z-value: 0.832
Transcription factors associated with Nr2e3:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Nr2e3 | ENSMUSG00000032292.2 | Nr2e3 |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.4 | 12.1 | GO:0048133 | germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728) |
| 2.0 | 6.0 | GO:0003345 | proepicardium cell migration involved in pericardium morphogenesis(GO:0003345) |
| 1.6 | 18.7 | GO:1900383 | regulation of synaptic plasticity by receptor localization to synapse(GO:1900383) |
| 1.5 | 12.1 | GO:0005513 | detection of calcium ion(GO:0005513) |
| 1.2 | 10.8 | GO:0071420 | cellular response to histamine(GO:0071420) |
| 1.1 | 3.3 | GO:0050975 | sensory perception of touch(GO:0050975) |
| 1.0 | 8.2 | GO:0097118 | neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118) |
| 0.9 | 6.5 | GO:0014819 | regulation of skeletal muscle contraction(GO:0014819) |
| 0.9 | 8.2 | GO:0006682 | galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) |
| 0.9 | 5.4 | GO:1903056 | positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056) |
| 0.9 | 3.6 | GO:0006710 | androgen catabolic process(GO:0006710) |
| 0.7 | 2.2 | GO:0060821 | inactivation of X chromosome by DNA methylation(GO:0060821) |
| 0.6 | 1.9 | GO:2000224 | testosterone biosynthetic process(GO:0061370) regulation of testosterone biosynthetic process(GO:2000224) |
| 0.6 | 1.7 | GO:0098886 | modification of dendritic spine(GO:0098886) |
| 0.5 | 2.5 | GO:1903361 | protein localization to basolateral plasma membrane(GO:1903361) |
| 0.5 | 3.0 | GO:0060075 | regulation of resting membrane potential(GO:0060075) |
| 0.4 | 11.9 | GO:0002091 | negative regulation of receptor internalization(GO:0002091) |
| 0.4 | 5.3 | GO:2000507 | positive regulation of energy homeostasis(GO:2000507) |
| 0.4 | 2.1 | GO:1905150 | regulation of voltage-gated sodium channel activity(GO:1905150) |
| 0.4 | 2.0 | GO:0036508 | protein deglycosylation involved in glycoprotein catabolic process(GO:0035977) protein demannosylation(GO:0036507) protein alpha-1,2-demannosylation(GO:0036508) glycoprotein ERAD pathway(GO:0097466) mannose trimming involved in glycoprotein ERAD pathway(GO:1904382) |
| 0.4 | 3.8 | GO:0006027 | glycosaminoglycan catabolic process(GO:0006027) |
| 0.4 | 1.9 | GO:0043314 | negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313) |
| 0.4 | 5.3 | GO:0043011 | myeloid dendritic cell differentiation(GO:0043011) |
| 0.4 | 7.4 | GO:0014051 | gamma-aminobutyric acid secretion(GO:0014051) |
| 0.3 | 1.0 | GO:0097401 | synaptic vesicle lumen acidification(GO:0097401) |
| 0.3 | 0.9 | GO:0030070 | insulin processing(GO:0030070) |
| 0.3 | 1.5 | GO:0032346 | positive regulation of aldosterone metabolic process(GO:0032346) positive regulation of aldosterone biosynthetic process(GO:0032349) |
| 0.3 | 4.4 | GO:0048672 | positive regulation of collateral sprouting(GO:0048672) |
| 0.3 | 2.0 | GO:1903690 | negative regulation of wound healing, spreading of epidermal cells(GO:1903690) |
| 0.3 | 1.1 | GO:0036091 | positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091) |
| 0.3 | 3.8 | GO:0043517 | positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) |
| 0.2 | 1.0 | GO:0072592 | oxygen metabolic process(GO:0072592) |
| 0.2 | 1.7 | GO:0098909 | establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909) |
| 0.2 | 9.4 | GO:0010614 | negative regulation of cardiac muscle hypertrophy(GO:0010614) |
| 0.2 | 4.2 | GO:0001553 | luteinization(GO:0001553) |
| 0.2 | 4.1 | GO:0071711 | basement membrane organization(GO:0071711) |
| 0.2 | 0.7 | GO:0099566 | regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566) |
| 0.2 | 0.5 | GO:0046022 | regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022) |
| 0.2 | 1.9 | GO:0015721 | bile acid and bile salt transport(GO:0015721) |
| 0.2 | 0.8 | GO:0030951 | establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) |
| 0.1 | 0.4 | GO:2000481 | positive regulation of cAMP-dependent protein kinase activity(GO:2000481) positive regulation of dendritic cell apoptotic process(GO:2000670) |
| 0.1 | 2.2 | GO:1904424 | regulation of GTP binding(GO:1904424) |
| 0.1 | 0.8 | GO:0002317 | plasma cell differentiation(GO:0002317) |
| 0.1 | 0.3 | GO:0003289 | atrial septum primum morphogenesis(GO:0003289) |
| 0.1 | 1.1 | GO:0035428 | hexose transmembrane transport(GO:0035428) |
| 0.1 | 1.3 | GO:0032876 | negative regulation of DNA endoreduplication(GO:0032876) |
| 0.1 | 11.2 | GO:0050885 | neuromuscular process controlling balance(GO:0050885) |
| 0.1 | 0.8 | GO:0051611 | negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) |
| 0.1 | 4.0 | GO:0008045 | motor neuron axon guidance(GO:0008045) |
| 0.1 | 0.8 | GO:0090074 | negative regulation of protein homodimerization activity(GO:0090074) |
| 0.1 | 0.4 | GO:0090309 | positive regulation of methylation-dependent chromatin silencing(GO:0090309) |
| 0.1 | 1.0 | GO:0090557 | establishment of endothelial intestinal barrier(GO:0090557) |
| 0.1 | 0.5 | GO:1990564 | protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592) |
| 0.1 | 1.1 | GO:0021527 | spinal cord association neuron differentiation(GO:0021527) |
| 0.1 | 0.3 | GO:0042636 | negative regulation of hair cycle(GO:0042636) regulation of catagen(GO:0051794) negative regulation of hair follicle development(GO:0051799) |
| 0.1 | 0.5 | GO:0015014 | heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014) |
| 0.1 | 2.9 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
| 0.1 | 1.5 | GO:2000114 | regulation of establishment of cell polarity(GO:2000114) |
| 0.1 | 1.8 | GO:0010842 | retina layer formation(GO:0010842) |
| 0.1 | 1.3 | GO:0007097 | nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023) |
| 0.1 | 1.0 | GO:0046069 | cGMP catabolic process(GO:0046069) |
| 0.0 | 1.5 | GO:0043171 | peptide catabolic process(GO:0043171) |
| 0.0 | 0.5 | GO:0010839 | negative regulation of keratinocyte proliferation(GO:0010839) |
| 0.0 | 0.6 | GO:0090129 | positive regulation of synapse maturation(GO:0090129) |
| 0.0 | 0.2 | GO:0060052 | neurofilament cytoskeleton organization(GO:0060052) |
| 0.0 | 0.2 | GO:0001980 | regulation of systemic arterial blood pressure by ischemic conditions(GO:0001980) |
| 0.0 | 3.5 | GO:0018107 | peptidyl-threonine phosphorylation(GO:0018107) |
| 0.0 | 1.6 | GO:1904893 | negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893) |
| 0.0 | 0.3 | GO:0090110 | cargo loading into COPII-coated vesicle(GO:0090110) |
| 0.0 | 1.1 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
| 0.0 | 0.2 | GO:0015074 | DNA integration(GO:0015074) |
| 0.0 | 1.8 | GO:0032411 | positive regulation of transporter activity(GO:0032411) |
| 0.0 | 0.6 | GO:0051091 | positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091) |
| 0.0 | 1.5 | GO:0007613 | memory(GO:0007613) |
| 0.0 | 5.7 | GO:0007186 | G-protein coupled receptor signaling pathway(GO:0007186) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 8.2 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
| 0.8 | 4.7 | GO:0005663 | DNA replication factor C complex(GO:0005663) |
| 0.7 | 3.0 | GO:1902937 | inward rectifier potassium channel complex(GO:1902937) |
| 0.7 | 10.8 | GO:1902711 | GABA-A receptor complex(GO:1902711) |
| 0.7 | 11.7 | GO:0031045 | dense core granule(GO:0031045) |
| 0.5 | 2.0 | GO:0030981 | cortical microtubule cytoskeleton(GO:0030981) |
| 0.4 | 1.5 | GO:0070022 | transforming growth factor beta receptor homodimeric complex(GO:0070022) |
| 0.4 | 2.5 | GO:0097025 | MPP7-DLG1-LIN7 complex(GO:0097025) |
| 0.3 | 2.2 | GO:0001740 | Barr body(GO:0001740) |
| 0.3 | 4.3 | GO:0042101 | T cell receptor complex(GO:0042101) |
| 0.3 | 3.9 | GO:0030122 | AP-2 adaptor complex(GO:0030122) |
| 0.2 | 1.0 | GO:0071438 | invadopodium membrane(GO:0071438) |
| 0.2 | 2.2 | GO:0045095 | keratin filament(GO:0045095) |
| 0.2 | 1.9 | GO:0034464 | BBSome(GO:0034464) |
| 0.2 | 1.5 | GO:0071437 | invadopodium(GO:0071437) |
| 0.1 | 6.5 | GO:0005790 | smooth endoplasmic reticulum(GO:0005790) |
| 0.1 | 7.4 | GO:0034704 | calcium channel complex(GO:0034704) |
| 0.1 | 1.0 | GO:0046581 | intercellular canaliculus(GO:0046581) |
| 0.1 | 0.6 | GO:0000308 | cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308) |
| 0.1 | 0.8 | GO:0005638 | lamin filament(GO:0005638) |
| 0.1 | 37.5 | GO:0045211 | postsynaptic membrane(GO:0045211) |
| 0.1 | 6.0 | GO:0044295 | axonal growth cone(GO:0044295) |
| 0.1 | 1.0 | GO:0042581 | specific granule(GO:0042581) |
| 0.1 | 8.4 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
| 0.1 | 9.1 | GO:0016605 | PML body(GO:0016605) |
| 0.1 | 2.0 | GO:0097440 | apical dendrite(GO:0097440) |
| 0.1 | 1.1 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) |
| 0.0 | 3.6 | GO:0005811 | lipid particle(GO:0005811) |
| 0.0 | 2.0 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.0 | 7.2 | GO:0030426 | growth cone(GO:0030426) |
| 0.0 | 1.7 | GO:0048786 | presynaptic active zone(GO:0048786) |
| 0.0 | 0.2 | GO:0097512 | cardiac myofibril(GO:0097512) cardiac Troponin complex(GO:1990584) |
| 0.0 | 0.2 | GO:0000938 | GARP complex(GO:0000938) |
| 0.0 | 2.1 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.0 | 5.3 | GO:0001650 | fibrillar center(GO:0001650) |
| 0.0 | 1.9 | GO:0001669 | acrosomal vesicle(GO:0001669) |
| 0.0 | 0.6 | GO:0042734 | presynaptic membrane(GO:0042734) |
| 0.0 | 0.4 | GO:0033655 | host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655) |
| 0.0 | 0.9 | GO:0031594 | neuromuscular junction(GO:0031594) |
| 0.0 | 0.3 | GO:0030127 | COPII vesicle coat(GO:0030127) |
| 0.0 | 0.4 | GO:0005721 | pericentric heterochromatin(GO:0005721) |
| 0.0 | 11.3 | GO:0005730 | nucleolus(GO:0005730) |
| 0.0 | 1.3 | GO:0042641 | actomyosin(GO:0042641) |
| 0.0 | 4.7 | GO:0005635 | nuclear envelope(GO:0005635) |
| 0.0 | 0.9 | GO:0043204 | perikaryon(GO:0043204) |
| 0.0 | 1.2 | GO:0036064 | ciliary basal body(GO:0036064) |
| 0.0 | 0.6 | GO:0031252 | cell leading edge(GO:0031252) |
| 0.0 | 0.2 | GO:0000124 | SAGA complex(GO:0000124) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.9 | 11.7 | GO:0030348 | syntaxin-3 binding(GO:0030348) |
| 2.1 | 8.2 | GO:0047275 | glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275) |
| 1.8 | 10.8 | GO:1904315 | GABA-gated chloride ion channel activity(GO:0022851) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315) |
| 1.4 | 8.2 | GO:0070699 | type II activin receptor binding(GO:0070699) |
| 0.8 | 6.5 | GO:0086008 | voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008) |
| 0.7 | 10.9 | GO:0045499 | chemorepellent activity(GO:0045499) |
| 0.7 | 11.9 | GO:0042043 | neurexin family protein binding(GO:0042043) |
| 0.6 | 3.8 | GO:0005173 | stem cell factor receptor binding(GO:0005173) |
| 0.5 | 6.3 | GO:0015279 | store-operated calcium channel activity(GO:0015279) |
| 0.5 | 3.6 | GO:0004303 | estradiol 17-beta-dehydrogenase activity(GO:0004303) |
| 0.5 | 1.9 | GO:0015349 | thyroid hormone transmembrane transporter activity(GO:0015349) |
| 0.5 | 1.9 | GO:0004692 | cGMP-dependent protein kinase activity(GO:0004692) |
| 0.4 | 0.4 | GO:0031697 | beta-1 adrenergic receptor binding(GO:0031697) |
| 0.4 | 5.3 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
| 0.4 | 4.7 | GO:0003689 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
| 0.4 | 2.5 | GO:0097016 | L27 domain binding(GO:0097016) |
| 0.4 | 18.3 | GO:0046875 | ephrin receptor binding(GO:0046875) |
| 0.3 | 1.0 | GO:0030171 | voltage-gated proton channel activity(GO:0030171) |
| 0.3 | 3.0 | GO:0022841 | potassium ion leak channel activity(GO:0022841) |
| 0.2 | 1.0 | GO:0072320 | volume-sensitive chloride channel activity(GO:0072320) |
| 0.2 | 2.0 | GO:0004571 | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) |
| 0.2 | 3.8 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.2 | 0.7 | GO:0001639 | PLC activating G-protein coupled glutamate receptor activity(GO:0001639) G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530) |
| 0.2 | 0.5 | GO:0071568 | UFM1 transferase activity(GO:0071568) |
| 0.2 | 6.1 | GO:0042805 | actinin binding(GO:0042805) |
| 0.2 | 6.7 | GO:0070412 | R-SMAD binding(GO:0070412) |
| 0.2 | 2.0 | GO:0002162 | dystroglycan binding(GO:0002162) |
| 0.1 | 1.0 | GO:0071253 | connexin binding(GO:0071253) |
| 0.1 | 1.0 | GO:0048101 | calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101) |
| 0.1 | 0.5 | GO:0042328 | heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328) |
| 0.1 | 1.5 | GO:0035615 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
| 0.1 | 2.0 | GO:0030159 | receptor signaling complex scaffold activity(GO:0030159) |
| 0.1 | 1.1 | GO:0005355 | glucose transmembrane transporter activity(GO:0005355) |
| 0.1 | 0.2 | GO:0003858 | 3-hydroxybutyrate dehydrogenase activity(GO:0003858) |
| 0.1 | 3.5 | GO:0004712 | protein serine/threonine/tyrosine kinase activity(GO:0004712) |
| 0.1 | 7.5 | GO:0005057 | receptor signaling protein activity(GO:0005057) |
| 0.1 | 1.8 | GO:0042169 | SH2 domain binding(GO:0042169) |
| 0.1 | 0.2 | GO:0030172 | troponin C binding(GO:0030172) |
| 0.1 | 1.7 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
| 0.0 | 20.8 | GO:0001228 | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228) |
| 0.0 | 1.9 | GO:0001103 | RNA polymerase II repressing transcription factor binding(GO:0001103) |
| 0.0 | 5.3 | GO:0001191 | transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191) |
| 0.0 | 3.1 | GO:0048365 | Rac GTPase binding(GO:0048365) |
| 0.0 | 1.1 | GO:0001221 | transcription cofactor binding(GO:0001221) |
| 0.0 | 1.5 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
| 0.0 | 0.8 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
| 0.0 | 0.6 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
| 0.0 | 0.5 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
| 0.0 | 0.4 | GO:0005537 | mannose binding(GO:0005537) |
| 0.0 | 0.4 | GO:0015269 | calcium-activated potassium channel activity(GO:0015269) |
| 0.0 | 2.2 | GO:0051219 | phosphoprotein binding(GO:0051219) |
| 0.0 | 1.1 | GO:0032934 | cholesterol binding(GO:0015485) sterol binding(GO:0032934) |
| 0.0 | 1.1 | GO:0001158 | enhancer sequence-specific DNA binding(GO:0001158) |
| 0.0 | 5.5 | GO:0008017 | microtubule binding(GO:0008017) |
| 0.0 | 0.6 | GO:0005246 | calcium channel regulator activity(GO:0005246) |
| 0.0 | 0.6 | GO:0030332 | cyclin binding(GO:0030332) |
| 0.0 | 0.9 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.0 | 0.4 | GO:0008028 | monocarboxylic acid transmembrane transporter activity(GO:0008028) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 12.1 | PID_IL12_STAT4_PATHWAY | IL12 signaling mediated by STAT4 |
| 0.2 | 11.7 | SIG_CD40PATHWAYMAP | Genes related to CD40 signaling |
| 0.1 | 5.3 | PID_PI3K_PLC_TRK_PATHWAY | Trk receptor signaling mediated by PI3K and PLC-gamma |
| 0.1 | 4.7 | PID_FAS_PATHWAY | FAS (CD95) signaling pathway |
| 0.1 | 4.4 | PID_LIS1_PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 0.1 | 3.8 | PID_KIT_PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
| 0.1 | 2.2 | PID_BETA_CATENIN_DEG_PATHWAY | Degradation of beta catenin |
| 0.1 | 0.5 | ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY | PI3K Pathway |
| 0.1 | 1.9 | PID_P38_ALPHA_BETA_PATHWAY | Regulation of p38-alpha and p38-beta |
| 0.1 | 1.4 | PID_HDAC_CLASSIII_PATHWAY | Signaling events mediated by HDAC Class III |
| 0.0 | 1.2 | ST_T_CELL_SIGNAL_TRANSDUCTION | T Cell Signal Transduction |
| 0.0 | 1.3 | PID_CDC42_PATHWAY | CDC42 signaling events |
| 0.0 | 1.1 | PID_IL6_7_PATHWAY | IL6-mediated signaling events |
| 0.0 | 1.5 | SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES | Genes related to the insulin receptor pathway |
| 0.0 | 1.6 | PID_RAC1_REG_PATHWAY | Regulation of RAC1 activity |
| 0.0 | 1.0 | PID_RAC1_PATHWAY | RAC1 signaling pathway |
| 0.0 | 1.5 | PID_TGFBR_PATHWAY | TGF-beta receptor signaling |
| 0.0 | 1.0 | PID_ECADHERIN_NASCENT_AJ_PATHWAY | E-cadherin signaling in the nascent adherens junction |
| 0.0 | 1.3 | PID_PLK1_PATHWAY | PLK1 signaling events |
| 0.0 | 0.8 | PID_CASPASE_PATHWAY | Caspase cascade in apoptosis |
| 0.0 | 0.4 | PID_TCPTP_PATHWAY | Signaling events mediated by TCPTP |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.2 | 11.7 | REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE | Genes involved in Acetylcholine Neurotransmitter Release Cycle |
| 0.7 | 7.4 | REACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN1_SIGNALING | Genes involved in Role of second messengers in netrin-1 signaling |
| 0.7 | 10.8 | REACTOME_GABA_A_RECEPTOR_ACTIVATION | Genes involved in GABA A receptor activation |
| 0.5 | 1.5 | REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY | Genes involved in Endosomal/Vacuolar pathway |
| 0.4 | 3.0 | REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS | Genes involved in Tandem pore domain potassium channels |
| 0.4 | 3.8 | REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
| 0.3 | 8.2 | REACTOME_NEPHRIN_INTERACTIONS | Genes involved in Nephrin interactions |
| 0.2 | 1.9 | REACTOME_TRANSPORT_OF_ORGANIC_ANIONS | Genes involved in Transport of organic anions |
| 0.2 | 2.0 | REACTOME_CALNEXIN_CALRETICULIN_CYCLE | Genes involved in Calnexin/calreticulin cycle |
| 0.2 | 6.4 | REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
| 0.1 | 6.2 | REACTOME_CA_DEPENDENT_EVENTS | Genes involved in Ca-dependent events |
| 0.1 | 1.0 | REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS | Genes involved in Apoptotic cleavage of cell adhesion proteins |
| 0.1 | 2.2 | REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE | Genes involved in Beta-catenin phosphorylation cascade |
| 0.1 | 1.5 | REACTOME_ACTIVATION_OF_RAC | Genes involved in Activation of Rac |
| 0.1 | 2.3 | REACTOME_CGMP_EFFECTS | Genes involved in cGMP effects |
| 0.1 | 1.1 | REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
| 0.1 | 0.7 | REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
| 0.1 | 1.5 | REACTOME_GAP_JUNCTION_DEGRADATION | Genes involved in Gap junction degradation |
| 0.1 | 8.7 | REACTOME_L1CAM_INTERACTIONS | Genes involved in L1CAM interactions |
| 0.1 | 1.8 | REACTOME_DEADENYLATION_OF_MRNA | Genes involved in Deadenylation of mRNA |
| 0.0 | 1.4 | REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA | Genes involved in Circadian Repression of Expression by REV-ERBA |
| 0.0 | 0.9 | REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING | Genes involved in Insulin Synthesis and Processing |
| 0.0 | 1.3 | REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY | Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity |
| 0.0 | 0.3 | REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC | Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC |
| 0.0 | 0.8 | REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS | Genes involved in Apoptotic cleavage of cellular proteins |
| 0.0 | 0.2 | REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |
| 0.0 | 1.4 | REACTOME_G_ALPHA1213_SIGNALLING_EVENTS | Genes involved in G alpha (12/13) signalling events |
| 0.0 | 1.3 | REACTOME_MITOTIC_PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.0 | 0.5 | REACTOME_HS_GAG_BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
| 0.0 | 0.4 | REACTOME_TRANSPORT_TO_THE_GOLGI_AND_SUBSEQUENT_MODIFICATION | Genes involved in Transport to the Golgi and subsequent modification |
| 0.0 | 0.7 | REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
