Motif ID: Nr5a2

Z-value: 0.850


Transcription factors associated with Nr5a2:

Gene SymbolEntrez IDGene Name
Nr5a2 ENSMUSG00000026398.8 Nr5a2



Activity profile for motif Nr5a2.

activity profile for motif Nr5a2


Sorted Z-values histogram for motif Nr5a2

Sorted Z-values for motif Nr5a2



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr5a2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_-_77347816 6.467 ENSMUST00000184138.1
ENSMUST00000184006.1
ENSMUST00000185144.1
ENSMUST00000034910.9
Mlip



muscular LMNA-interacting protein



chr10_+_79716588 5.654 ENSMUST00000099513.1
ENSMUST00000020581.2
Hcn2

hyperpolarization-activated, cyclic nucleotide-gated K+ 2

chr9_-_77347787 5.530 ENSMUST00000184848.1
ENSMUST00000184415.1
Mlip

muscular LMNA-interacting protein

chr9_-_77347889 4.646 ENSMUST00000185039.1
Mlip
muscular LMNA-interacting protein
chr2_+_121357714 4.474 ENSMUST00000125812.1
ENSMUST00000078222.2
ENSMUST00000125221.1
ENSMUST00000150271.1
Ckmt1



creatine kinase, mitochondrial 1, ubiquitous



chr19_+_6399857 4.321 ENSMUST00000146601.1
ENSMUST00000150713.1
Rasgrp2

RAS, guanyl releasing protein 2

chr15_+_3270767 4.295 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
Sepp1



selenoprotein P, plasma, 1



chr8_+_124793013 4.114 ENSMUST00000167588.1
Trim67
tripartite motif-containing 67
chr11_-_4704334 4.046 ENSMUST00000058407.5
Uqcr10
ubiquinol-cytochrome c reductase, complex III subunit X
chr8_+_124793061 3.969 ENSMUST00000041106.7
Trim67
tripartite motif-containing 67
chr2_-_73911323 3.857 ENSMUST00000111996.1
ENSMUST00000018914.2
Atp5g3

ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9)

chr15_-_79804717 3.841 ENSMUST00000023057.8
Nptxr
neuronal pentraxin receptor
chr2_+_121358591 3.668 ENSMUST00000000317.6
ENSMUST00000129130.1
Ckmt1

creatine kinase, mitochondrial 1, ubiquitous

chr19_+_6400523 3.620 ENSMUST00000146831.1
ENSMUST00000035716.8
ENSMUST00000138555.1
ENSMUST00000167240.1
Rasgrp2



RAS, guanyl releasing protein 2



chr11_+_98741805 3.576 ENSMUST00000064187.5
Thra
thyroid hormone receptor alpha
chr16_+_18776839 3.513 ENSMUST00000043577.1
Cldn5
claudin 5
chr1_-_134235420 3.363 ENSMUST00000038191.6
ENSMUST00000086465.4
Adora1

adenosine A1 receptor

chr3_-_54915867 3.135 ENSMUST00000070342.3
Sertm1
serine rich and transmembrane domain containing 1
chr19_+_6399746 3.091 ENSMUST00000113468.1
Rasgrp2
RAS, guanyl releasing protein 2
chr7_-_110862944 3.023 ENSMUST00000033050.3
Lyve1
lymphatic vessel endothelial hyaluronan receptor 1
chr16_-_91931643 2.882 ENSMUST00000023677.3
Atp5o
ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit
chr7_+_46847128 2.848 ENSMUST00000005051.4
Ldha
lactate dehydrogenase A
chr8_+_94152607 2.826 ENSMUST00000034211.8
Mt3
metallothionein 3
chr19_-_46327121 2.823 ENSMUST00000041391.4
ENSMUST00000096029.5
Psd

pleckstrin and Sec7 domain containing

chr6_+_90550789 2.789 ENSMUST00000130418.1
ENSMUST00000032175.8
Aldh1l1

aldehyde dehydrogenase 1 family, member L1

chr18_+_6332587 2.771 ENSMUST00000097682.2
Rpl27-ps3
ribosomal protein L27, pseudogene 3
chr4_-_116017854 2.760 ENSMUST00000049095.5
Faah
fatty acid amide hydrolase
chr18_+_37955685 2.759 ENSMUST00000169498.2
Rell2
RELT-like 2
chr19_-_57314896 2.757 ENSMUST00000111524.1
Ablim1
actin-binding LIM protein 1
chr11_+_6415443 2.754 ENSMUST00000132846.1
Ppia
peptidylprolyl isomerase A
chr6_-_135168162 2.751 ENSMUST00000045855.7
Hebp1
heme binding protein 1
chrM_+_8600 2.744 ENSMUST00000082409.1
mt-Co3
mitochondrially encoded cytochrome c oxidase III
chr18_+_37955544 2.729 ENSMUST00000070709.2
ENSMUST00000177058.1
ENSMUST00000169360.2
ENSMUST00000163591.2
ENSMUST00000091932.5
Rell2




RELT-like 2




chr15_+_85116829 2.690 ENSMUST00000105085.1
Gm10923
predicted gene 10923
chr1_+_45981548 2.669 ENSMUST00000085632.2
Rpl23a-ps1
ribosomal protein 23A, pseudogene 1
chr7_-_105482197 2.632 ENSMUST00000047040.2
Prkcdbp
protein kinase C, delta binding protein
chr1_-_167393826 2.624 ENSMUST00000028005.2
Mgst3
microsomal glutathione S-transferase 3
chr2_+_140170641 2.554 ENSMUST00000044825.4
Ndufaf5
NADH dehydrogenase (ubiquinone) complex I, assembly factor 5
chr14_+_34170640 2.542 ENSMUST00000104925.3
Rpl23a-ps3
ribosomal protein L23A, pseudogene 3
chr11_+_67586520 2.524 ENSMUST00000108682.2
Gas7
growth arrest specific 7
chr4_-_139131058 2.454 ENSMUST00000143971.1
Minos1
mitochondrial inner membrane organizing system 1
chr11_+_58948890 2.453 ENSMUST00000078267.3
Hist3h2ba
histone cluster 3, H2ba
chr11_+_67586675 2.451 ENSMUST00000108680.1
Gas7
growth arrest specific 7
chr11_+_69088490 2.379 ENSMUST00000021273.6
ENSMUST00000117780.1
Vamp2

vesicle-associated membrane protein 2

chr14_-_77252327 2.368 ENSMUST00000099431.4
Gm10132
predicted gene 10132
chr1_-_52091066 2.367 ENSMUST00000105087.1
Gm3940
predicted gene 3940
chr11_+_120484613 2.343 ENSMUST00000043627.7
Mrpl12
mitochondrial ribosomal protein L12
chr19_-_7217549 2.319 ENSMUST00000039758.4
Cox8a
cytochrome c oxidase subunit VIIIa
chr15_+_85510812 2.290 ENSMUST00000079690.2
Gm4825
predicted pseudogene 4825
chr11_-_59839745 2.281 ENSMUST00000141415.1
Cops3
COP9 (constitutive photomorphogenic) homolog, subunit 3 (Arabidopsis thaliana)
chr4_+_42917234 2.255 ENSMUST00000107976.2
ENSMUST00000069184.2
N28178

expressed sequence N28178

chr1_-_51941261 2.231 ENSMUST00000097103.3
Gm8420
predicted gene 8420
chr13_-_102958084 2.182 ENSMUST00000099202.3
ENSMUST00000172264.1
Mast4

microtubule associated serine/threonine kinase family member 4

chr12_-_86988676 2.163 ENSMUST00000095521.2
Zdhhc22
zinc finger, DHHC-type containing 22
chr13_-_21501418 2.150 ENSMUST00000044043.2
Gm11273
predicted gene 11273
chr19_-_47090610 2.135 ENSMUST00000096014.3
Usmg5
upregulated during skeletal muscle growth 5
chr4_+_42916647 2.126 ENSMUST00000132173.1
ENSMUST00000107975.1
N28178

expressed sequence N28178

chr7_-_141429351 2.117 ENSMUST00000164387.1
ENSMUST00000137488.1
ENSMUST00000084436.3
Cend1


cell cycle exit and neuronal differentiation 1


chr15_-_35938009 2.084 ENSMUST00000156915.1
Cox6c
cytochrome c oxidase subunit VIc
chr10_+_14523062 2.079 ENSMUST00000096020.5
Gm10335
predicted gene 10335
chr19_-_5085483 2.055 ENSMUST00000140389.1
ENSMUST00000151413.1
ENSMUST00000077066.7
Tmem151a


transmembrane protein 151A


chr3_+_14886426 2.031 ENSMUST00000029078.7
Car2
carbonic anhydrase 2
chr2_+_19658055 2.012 ENSMUST00000052168.4
Otud1
OTU domain containing 1
chr7_+_100494044 1.997 ENSMUST00000153287.1
Ucp2
uncoupling protein 2 (mitochondrial, proton carrier)
chr7_-_19665005 1.989 ENSMUST00000055242.9
Clptm1
cleft lip and palate associated transmembrane protein 1
chr7_+_100493795 1.954 ENSMUST00000129324.1
Ucp2
uncoupling protein 2 (mitochondrial, proton carrier)
chr6_-_113531575 1.951 ENSMUST00000032425.5
Emc3
ER membrane protein complex subunit 3
chr10_+_94198955 1.939 ENSMUST00000020209.9
ENSMUST00000179990.1
Ndufa12

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12

chr8_+_120668308 1.921 ENSMUST00000181795.1
Cox4i1
cytochrome c oxidase subunit IV isoform 1
chr8_+_120668222 1.920 ENSMUST00000034276.6
ENSMUST00000181586.1
Cox4i1

cytochrome c oxidase subunit IV isoform 1

chr8_+_46490968 1.916 ENSMUST00000110372.1
ENSMUST00000130563.1
Acsl1

acyl-CoA synthetase long-chain family member 1

chr2_-_64975762 1.915 ENSMUST00000156765.1
Grb14
growth factor receptor bound protein 14
chr13_-_52929458 1.912 ENSMUST00000123599.1
Auh
AU RNA binding protein/enoyl-coenzyme A hydratase
chr15_-_35938186 1.909 ENSMUST00000014457.8
Cox6c
cytochrome c oxidase subunit VIc
chr6_+_30541582 1.902 ENSMUST00000096066.4
Cpa2
carboxypeptidase A2, pancreatic
chr10_-_125328957 1.883 ENSMUST00000063318.2
Slc16a7
solute carrier family 16 (monocarboxylic acid transporters), member 7
chr6_-_91473361 1.850 ENSMUST00000040835.7
Chchd4
coiled-coil-helix-coiled-coil-helix domain containing 4
chr12_+_105032638 1.842 ENSMUST00000021522.3
Glrx5
glutaredoxin 5 homolog (S. cerevisiae)
chr8_-_70523085 1.832 ENSMUST00000137610.1
ENSMUST00000121623.1
ENSMUST00000093456.5
ENSMUST00000118850.1
Kxd1



KxDL motif containing 1



chr8_+_71464910 1.832 ENSMUST00000048914.6
Mrpl34
mitochondrial ribosomal protein L34
chr1_-_171222435 1.818 ENSMUST00000147246.1
ENSMUST00000111326.1
ENSMUST00000138184.1
Tomm40l


translocase of outer mitochondrial membrane 40 homolog-like (yeast)


chr17_-_25868727 1.805 ENSMUST00000026828.5
Fam195a
family with sequence similarity 195, member A
chr13_+_21787461 1.793 ENSMUST00000110473.2
ENSMUST00000102982.1
Hist1h2bp

histone cluster 1, H2bp

chr19_-_3912711 1.756 ENSMUST00000075092.6
Ndufs8
NADH dehydrogenase (ubiquinone) Fe-S protein 8
chr9_-_107668967 1.755 ENSMUST00000177567.1
Slc38a3
solute carrier family 38, member 3
chr2_+_30416096 1.754 ENSMUST00000113601.3
ENSMUST00000113603.3
Ppp2r4

protein phosphatase 2A, regulatory subunit B (PR 53)

chr1_+_36691487 1.753 ENSMUST00000081180.4
Cox5b
cytochrome c oxidase subunit Vb
chr7_-_141429433 1.749 ENSMUST00000124444.1
Cend1
cell cycle exit and neuronal differentiation 1
chr19_+_6400611 1.748 ENSMUST00000113467.1
Rasgrp2
RAS, guanyl releasing protein 2
chr15_-_79285502 1.748 ENSMUST00000165408.1
Baiap2l2
BAI1-associated protein 2-like 2
chr4_+_140961203 1.742 ENSMUST00000010007.8
Sdhb
succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
chr4_-_45108038 1.737 ENSMUST00000107809.2
ENSMUST00000107808.2
ENSMUST00000107807.1
ENSMUST00000107810.2
Tomm5



translocase of outer mitochondrial membrane 5 homolog (yeast)



chr6_+_91156772 1.731 ENSMUST00000143621.1
Hdac11
histone deacetylase 11
chrX_+_142825698 1.714 ENSMUST00000112888.1
Tmem164
transmembrane protein 164
chr15_-_52478228 1.711 ENSMUST00000081993.1
Gm10020
predicted pseudogene 10020
chr7_-_100583072 1.702 ENSMUST00000152876.1
ENSMUST00000150042.1
Mrpl48

mitochondrial ribosomal protein L48

chr11_-_59839828 1.696 ENSMUST00000019517.3
Cops3
COP9 (constitutive photomorphogenic) homolog, subunit 3 (Arabidopsis thaliana)
chr1_-_171222508 1.676 ENSMUST00000005817.2
Tomm40l
translocase of outer mitochondrial membrane 40 homolog-like (yeast)
chr9_-_107710475 1.670 ENSMUST00000080560.3
Sema3f
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr1_+_131970589 1.634 ENSMUST00000027695.6
Slc45a3
solute carrier family 45, member 3
chr18_+_77773956 1.597 ENSMUST00000114748.1
Atp5a1
ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1
chr17_-_83631892 1.595 ENSMUST00000051482.1
Kcng3
potassium voltage-gated channel, subfamily G, member 3
chr9_-_106685653 1.589 ENSMUST00000163441.1
Tex264
testis expressed gene 264
chr9_-_106891870 1.571 ENSMUST00000160503.1
ENSMUST00000159620.2
ENSMUST00000160978.1
Manf


mesencephalic astrocyte-derived neurotrophic factor


chr3_-_107517321 1.548 ENSMUST00000166892.1
Slc6a17
solute carrier family 6 (neurotransmitter transporter), member 17
chr2_-_157566319 1.539 ENSMUST00000109528.2
ENSMUST00000088494.2
Blcap

bladder cancer associated protein homolog (human)

chr7_+_78783119 1.526 ENSMUST00000032840.4
Mrps11
mitochondrial ribosomal protein S11
chr19_-_5366626 1.498 ENSMUST00000025762.8
Banf1
barrier to autointegration factor 1
chr9_-_50603792 1.491 ENSMUST00000000175.4
Sdhd
succinate dehydrogenase complex, subunit D, integral membrane protein
chr14_-_103844173 1.486 ENSMUST00000022718.3
Ednrb
endothelin receptor type B
chr10_-_78464853 1.486 ENSMUST00000105385.1
Pdxk
pyridoxal (pyridoxine, vitamin B6) kinase
chr11_+_76407143 1.477 ENSMUST00000021203.6
ENSMUST00000152183.1
Timm22

translocase of inner mitochondrial membrane 22

chr10_-_80855187 1.474 ENSMUST00000035775.8
Lsm7
LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr10_-_78464969 1.474 ENSMUST00000041616.8
Pdxk
pyridoxal (pyridoxine, vitamin B6) kinase
chr13_-_21787218 1.466 ENSMUST00000091751.2
Hist1h2an
histone cluster 1, H2an
chr2_+_30416031 1.453 ENSMUST00000042055.3
Ppp2r4
protein phosphatase 2A, regulatory subunit B (PR 53)
chr11_-_69560186 1.452 ENSMUST00000004036.5
Efnb3
ephrin B3
chr19_-_60874526 1.447 ENSMUST00000025961.6
Prdx3
peroxiredoxin 3
chr11_-_3504766 1.440 ENSMUST00000044507.5
Inpp5j
inositol polyphosphate 5-phosphatase J
chr17_-_35916323 1.436 ENSMUST00000172642.1
ENSMUST00000174807.1
ENSMUST00000174349.1
ENSMUST00000025305.9
ENSMUST00000113782.3
Mrps18b




mitochondrial ribosomal protein S18B




chr5_+_117363513 1.431 ENSMUST00000111959.1
Wsb2
WD repeat and SOCS box-containing 2
chr2_+_103970115 1.418 ENSMUST00000111143.1
ENSMUST00000138815.1
Lmo2

LIM domain only 2

chr7_-_4522427 1.414 ENSMUST00000098859.3
Tnni3
troponin I, cardiac 3
chr12_+_12911986 1.412 ENSMUST00000085720.1
Rpl36-ps3
ribosomal protein L36, pseudogene 3
chr7_-_142576492 1.411 ENSMUST00000140716.1
H19
H19 fetal liver mRNA
chr14_+_58072686 1.408 ENSMUST00000022545.7
Fgf9
fibroblast growth factor 9
chr15_-_77928925 1.399 ENSMUST00000109748.2
ENSMUST00000109747.2
ENSMUST00000100486.5
ENSMUST00000005487.5
Txn2



thioredoxin 2



chr8_-_13494479 1.397 ENSMUST00000033828.5
Gas6
growth arrest specific 6
chr12_-_34291092 1.375 ENSMUST00000166546.2
Gm18025
predicted gene, 18025
chr8_+_84970068 1.361 ENSMUST00000164807.1
Prdx2
peroxiredoxin 2
chr19_-_5366285 1.359 ENSMUST00000170010.1
Banf1
barrier to autointegration factor 1
chr6_+_91156665 1.355 ENSMUST00000041736.4
Hdac11
histone deacetylase 11
chr11_+_90638127 1.354 ENSMUST00000020851.8
Cox11
cytochrome c oxidase assembly protein 11
chrX_-_141874870 1.345 ENSMUST00000182079.1
Gm15294
predicted gene 15294
chr2_+_103970221 1.344 ENSMUST00000111140.2
ENSMUST00000111139.2
Lmo2

LIM domain only 2

chr6_-_113501818 1.336 ENSMUST00000101059.1
Prrt3
proline-rich transmembrane protein 3
chr17_+_24470393 1.334 ENSMUST00000053024.6
Pgp
phosphoglycolate phosphatase
chr9_+_50603892 1.311 ENSMUST00000044051.4
Timm8b
translocase of inner mitochondrial membrane 8B
chr11_-_53430779 1.306 ENSMUST00000061326.4
ENSMUST00000109021.3
Uqcrq

ubiquinol-cytochrome c reductase, complex III subunit VII

chr9_-_44920698 1.302 ENSMUST00000043675.7
Atp5l
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit g
chr12_-_111966954 1.296 ENSMUST00000021719.5
2010107E04Rik
RIKEN cDNA 2010107E04 gene
chr2_-_147186389 1.292 ENSMUST00000109970.3
ENSMUST00000067075.5
Nkx2-2

NK2 homeobox 2

chr1_-_120074023 1.289 ENSMUST00000056089.7
Tmem37
transmembrane protein 37
chr7_-_105574324 1.281 ENSMUST00000081165.7
Apbb1
amyloid beta (A4) precursor protein-binding, family B, member 1
chr6_+_39592569 1.280 ENSMUST00000135671.1
ENSMUST00000119379.1
Ndufb2

NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2

chr18_-_15063560 1.277 ENSMUST00000168989.1
Kctd1
potassium channel tetramerisation domain containing 1
chr9_+_109832749 1.253 ENSMUST00000147777.1
ENSMUST00000035053.5
ENSMUST00000133483.1
Nme6


NME/NM23 nucleoside diphosphate kinase 6


chr2_+_32628390 1.245 ENSMUST00000156578.1
Ak1
adenylate kinase 1
chr9_+_123150941 1.244 ENSMUST00000026890.4
Clec3b
C-type lectin domain family 3, member b
chr4_-_134535382 1.241 ENSMUST00000116279.3
ENSMUST00000146808.1
Mtfr1l

mitochondrial fission regulator 1-like

chr4_+_63558748 1.240 ENSMUST00000077709.4
6330416G13Rik
RIKEN cDNA 6330416G13 gene
chr1_+_75435930 1.231 ENSMUST00000037796.7
ENSMUST00000113584.1
ENSMUST00000145166.1
ENSMUST00000143730.1
ENSMUST00000133418.1
ENSMUST00000144874.1
ENSMUST00000140287.1
Gmppa






GDP-mannose pyrophosphorylase A






chr9_-_70141484 1.230 ENSMUST00000034749.8
Fam81a
family with sequence similarity 81, member A
chr9_+_109832998 1.230 ENSMUST00000119376.1
ENSMUST00000122343.1
Nme6

NME/NM23 nucleoside diphosphate kinase 6

chr1_+_75546258 1.227 ENSMUST00000124341.1
Slc4a3
solute carrier family 4 (anion exchanger), member 3
chr6_+_91157373 1.227 ENSMUST00000155007.1
Hdac11
histone deacetylase 11
chr8_+_105701624 1.222 ENSMUST00000093195.6
Pard6a
par-6 (partitioning defective 6,) homolog alpha (C. elegans)
chr4_+_138250403 1.218 ENSMUST00000105818.1
ENSMUST00000105824.1
ENSMUST00000124239.1
Kif17
Sh2d5

kinesin family member 17
SH2 domain containing 5

chr14_+_32321987 1.207 ENSMUST00000022480.7
Ogdhl
oxoglutarate dehydrogenase-like
chr8_-_105295934 1.188 ENSMUST00000057855.3
Exoc3l
exocyst complex component 3-like
chr4_+_138250462 1.171 ENSMUST00000105823.1
Sh2d5
SH2 domain containing 5
chr13_+_98354234 1.168 ENSMUST00000105098.3
Foxd1
forkhead box D1
chr11_-_109298121 1.148 ENSMUST00000020920.3
Rgs9
regulator of G-protein signaling 9
chr15_+_76343504 1.147 ENSMUST00000023210.6
Cyc1
cytochrome c-1
chr12_-_71136611 1.137 ENSMUST00000021486.8
ENSMUST00000166120.1
Timm9

translocase of inner mitochondrial membrane 9

chr1_+_181352618 1.132 ENSMUST00000161880.1
ENSMUST00000027795.7
Cnih3

cornichon homolog 3 (Drosophila)

chr14_+_25694170 1.130 ENSMUST00000022419.6
Ppif
peptidylprolyl isomerase F (cyclophilin F)
chr4_+_123233556 1.129 ENSMUST00000040821.4
Heyl
hairy/enhancer-of-split related with YRPW motif-like
chrX_-_71492592 1.120 ENSMUST00000080035.4
Cd99l2
CD99 antigen-like 2
chr3_+_32736990 1.119 ENSMUST00000127477.1
ENSMUST00000121778.1
ENSMUST00000154257.1
Ndufb5


NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5


chr11_+_121702591 1.114 ENSMUST00000125580.1
Metrnl
meteorin, glial cell differentiation regulator-like
chr8_-_120668058 1.112 ENSMUST00000181950.1
ENSMUST00000181333.1
Emc8
Gm27021
ER membrane protein complex subunit 8
predicted gene, 27021
chr2_-_166155624 1.106 ENSMUST00000109249.2
Sulf2
sulfatase 2
chr10_-_62507737 1.105 ENSMUST00000020271.6
Srgn
serglycin
chr13_+_22043189 1.100 ENSMUST00000110452.1
Hist1h2bj
histone cluster 1, H2bj
chr11_+_74619594 1.096 ENSMUST00000100866.2
E130309D14Rik
RIKEN cDNA E130309D14 gene
chr9_+_57910974 1.092 ENSMUST00000163329.1
Ubl7
ubiquitin-like 7 (bone marrow stromal cell-derived)
chr7_+_80343091 1.091 ENSMUST00000032747.5
Hddc3
HD domain containing 3
chr2_-_131160006 1.088 ENSMUST00000103188.3
ENSMUST00000133602.1
ENSMUST00000028800.5
1700037H04Rik


RIKEN cDNA 1700037H04 gene


chr1_+_135146782 1.084 ENSMUST00000027684.4
Arl8a
ADP-ribosylation factor-like 8A
chr2_-_26604267 1.082 ENSMUST00000028286.5
Agpat2
1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)
chr9_+_108002501 1.079 ENSMUST00000035214.4
ENSMUST00000175874.1
Ip6k1

inositol hexaphosphate kinase 1

chr4_-_134535047 1.069 ENSMUST00000154769.1
Mtfr1l
mitochondrial fission regulator 1-like
chr9_+_107296843 1.058 ENSMUST00000167072.1
Cish
cytokine inducible SH2-containing protein
chr15_+_68928414 1.056 ENSMUST00000022954.6
Khdrbs3
KH domain containing, RNA binding, signal transduction associated 3
chr2_-_84678051 1.031 ENSMUST00000053664.8
ENSMUST00000111664.1
Tmx2

thioredoxin-related transmembrane protein 2

chr4_-_36136463 1.023 ENSMUST00000098151.2
Lingo2
leucine rich repeat and Ig domain containing 2
chr2_+_36136384 1.020 ENSMUST00000028250.2
Mrrf
mitochondrial ribosome recycling factor
chrX_+_20662898 1.017 ENSMUST00000001989.8
Uba1
ubiquitin-like modifier activating enzyme 1
chr8_-_120668003 1.015 ENSMUST00000181334.1
Emc8
ER membrane protein complex subunit 8
chr14_-_21848924 1.008 ENSMUST00000124549.1
Comtd1
catechol-O-methyltransferase domain containing 1
chr9_-_106891401 1.000 ENSMUST00000069036.7
Manf
mesencephalic astrocyte-derived neurotrophic factor
chrX_-_72656135 0.995 ENSMUST00000055966.6
Gabra3
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 3
chr4_-_134535268 0.990 ENSMUST00000102550.3
Mtfr1l
mitochondrial fission regulator 1-like
chr15_+_98108465 0.981 ENSMUST00000051226.6
Pfkm
phosphofructokinase, muscle
chr15_-_98728120 0.978 ENSMUST00000003445.6
Fkbp11
FK506 binding protein 11
chr7_+_120635176 0.967 ENSMUST00000033176.5
Uqcrc2
ubiquinol cytochrome c reductase core protein 2
chr2_-_26021532 0.964 ENSMUST00000136750.1
Ubac1
ubiquitin associated domain containing 1
chr4_+_138434647 0.959 ENSMUST00000044058.4
ENSMUST00000105813.1
ENSMUST00000105815.1
Mul1


mitochondrial ubiquitin ligase activator of NFKB 1


chr13_-_56296551 0.948 ENSMUST00000021970.9
Cxcl14
chemokine (C-X-C motif) ligand 14

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.9 GO:0021933 radial glia guided migration of cerebellar granule cell(GO:0021933)
1.2 3.6 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
1.1 5.7 GO:0070305 response to cGMP(GO:0070305) cellular response to cGMP(GO:0071321)
1.1 3.4 GO:0032241 positive regulation of nucleobase-containing compound transport(GO:0032241) regulation of nucleoside transport(GO:0032242) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256)
1.0 3.0 GO:0042823 pyridoxal phosphate biosynthetic process(GO:0042823)
1.0 5.8 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
1.0 2.9 GO:0019043 establishment of viral latency(GO:0019043)
0.9 2.8 GO:0042560 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.9 2.8 GO:0097212 lysosomal membrane organization(GO:0097212)
0.9 2.6 GO:0002014 vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure(GO:0002014)
0.8 2.4 GO:0002447 eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308)
0.8 6.9 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.7 1.4 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.7 2.0 GO:0035672 regulation of cellular pH reduction(GO:0032847) oligopeptide transmembrane transport(GO:0035672)
0.6 3.2 GO:0019244 lactate biosynthetic process from pyruvate(GO:0019244)
0.6 1.9 GO:1903538 meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.6 1.8 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.6 5.9 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.6 3.5 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.6 1.2 GO:0072076 nephrogenic mesenchyme development(GO:0072076)
0.6 1.7 GO:0019401 alditol biosynthetic process(GO:0019401)
0.6 1.7 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.5 1.6 GO:0001980 regulation of systemic arterial blood pressure by ischemic conditions(GO:0001980)
0.5 1.6 GO:0015772 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.5 2.6 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.5 1.5 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.5 1.9 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.5 1.4 GO:0071544 diphosphoinositol polyphosphate catabolic process(GO:0071544)
0.4 4.0 GO:1990845 adaptive thermogenesis(GO:1990845)
0.4 1.3 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.4 0.9 GO:0006106 fumarate metabolic process(GO:0006106)
0.4 17.3 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.4 1.1 GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.4 1.1 GO:2000823 regulation of androgen receptor activity(GO:2000823)
0.4 1.1 GO:0046133 pyrimidine ribonucleoside catabolic process(GO:0046133)
0.4 0.7 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100)
0.4 1.8 GO:0015817 glutamine transport(GO:0006868) histidine transport(GO:0015817) cellular response to potassium ion starvation(GO:0051365)
0.3 7.9 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.3 1.0 GO:0071649 regulation of chemokine (C-C motif) ligand 5 production(GO:0071649)
0.3 0.9 GO:2000501 natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501)
0.3 1.2 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.3 8.1 GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
0.3 0.6 GO:0042939 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.3 1.5 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.3 3.0 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.3 2.3 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.3 1.4 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.3 0.6 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.3 1.7 GO:1902287 trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.3 1.7 GO:0006172 ADP biosynthetic process(GO:0006172)
0.3 1.1 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.3 2.8 GO:0002536 respiratory burst involved in inflammatory response(GO:0002536) negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.3 4.3 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.3 1.0 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.2 0.7 GO:0010360 negative regulation of anion channel activity(GO:0010360)
0.2 2.0 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.2 4.0 GO:0000338 protein deneddylation(GO:0000338)
0.2 1.8 GO:0009249 protein lipoylation(GO:0009249)
0.2 2.5 GO:0046051 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.2 1.2 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
0.2 0.6 GO:0030210 heparin biosynthetic process(GO:0030210)
0.2 2.5 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.2 0.6 GO:1901856 negative regulation of cellular respiration(GO:1901856)
0.2 0.7 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.2 1.4 GO:0016576 histone dephosphorylation(GO:0016576)
0.2 1.7 GO:0006105 succinate metabolic process(GO:0006105)
0.2 2.6 GO:0018195 peptidyl-arginine modification(GO:0018195)
0.2 9.2 GO:0071277 cellular response to calcium ion(GO:0071277)
0.2 1.0 GO:0061622 glycolytic process through glucose-1-phosphate(GO:0061622)
0.2 1.5 GO:0016198 axon choice point recognition(GO:0016198)
0.2 1.9 GO:0044539 long-chain fatty acid import(GO:0044539)
0.2 1.1 GO:0014850 response to muscle activity(GO:0014850)
0.2 0.8 GO:0046684 response to pyrethroid(GO:0046684)
0.2 1.2 GO:1904781 positive regulation of protein localization to centrosome(GO:1904781)
0.1 0.7 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.1 1.0 GO:0032790 ribosome disassembly(GO:0032790)
0.1 0.7 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.1 2.8 GO:0034389 lipid particle organization(GO:0034389)
0.1 7.3 GO:0009060 aerobic respiration(GO:0009060)
0.1 1.0 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1 0.4 GO:0032237 activation of store-operated calcium channel activity(GO:0032237)
0.1 0.4 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
0.1 1.2 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.1 2.2 GO:0009081 branched-chain amino acid metabolic process(GO:0009081) branched-chain amino acid catabolic process(GO:0009083)
0.1 0.5 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.1 1.4 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.1 0.5 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.1 0.4 GO:1903279 regulation of calcium:sodium antiporter activity(GO:1903279)
0.1 1.1 GO:0006020 inositol metabolic process(GO:0006020)
0.1 0.4 GO:0061588 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylserine scrambling(GO:0061589) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.1 0.7 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.1 4.2 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1 0.8 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.1 0.2 GO:0009814 defense response, incompatible interaction(GO:0009814)
0.1 1.4 GO:0030238 male sex determination(GO:0030238)
0.1 0.6 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.1 4.3 GO:0014003 oligodendrocyte development(GO:0014003)
0.1 1.2 GO:0051601 exocyst localization(GO:0051601)
0.1 1.7 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 1.4 GO:0006662 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.1 2.0 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.1 1.1 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.1 2.0 GO:2000398 regulation of T cell differentiation in thymus(GO:0033081) regulation of thymocyte aggregation(GO:2000398)
0.1 1.5 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 0.7 GO:0009644 response to high light intensity(GO:0009644)
0.1 0.5 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.1 2.2 GO:0018345 protein palmitoylation(GO:0018345)
0.1 0.4 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.1 1.4 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.1 0.3 GO:0006741 NADP biosynthetic process(GO:0006741)
0.1 0.4 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 0.3 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.1 0.5 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.1 0.8 GO:0002227 innate immune response in mucosa(GO:0002227)
0.1 0.6 GO:0038203 TORC2 signaling(GO:0038203)
0.1 0.4 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.1 2.4 GO:0042168 heme metabolic process(GO:0042168)
0.1 0.3 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.1 6.7 GO:0006334 nucleosome assembly(GO:0006334)
0.1 1.5 GO:0030262 apoptotic nuclear changes(GO:0030262)
0.0 0.7 GO:0021860 pyramidal neuron development(GO:0021860)
0.0 1.1 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 1.6 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.5 GO:0051683 establishment of Golgi localization(GO:0051683)
0.0 4.0 GO:0032091 negative regulation of protein binding(GO:0032091)
0.0 4.9 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 1.1 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 2.9 GO:0051453 regulation of intracellular pH(GO:0051453)
0.0 1.3 GO:0045739 positive regulation of DNA repair(GO:0045739)
0.0 3.6 GO:0006342 chromatin silencing(GO:0006342)
0.0 1.0 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.9 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 5.0 GO:0030041 actin filament polymerization(GO:0030041)
0.0 1.9 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 0.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.8 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.8 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.0 0.4 GO:0042026 protein refolding(GO:0042026)
0.0 0.1 GO:0034982 mitochondrial protein processing(GO:0034982)
0.0 0.7 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.1 GO:1900365 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248) positive regulation of mRNA polyadenylation(GO:1900365)
0.0 0.4 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 1.0 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.3 GO:0042775 mitochondrial ATP synthesis coupled electron transport(GO:0042775)
0.0 0.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.4 GO:0098743 cartilage condensation(GO:0001502) cell aggregation(GO:0098743)
0.0 0.4 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.0 0.7 GO:0045471 response to ethanol(GO:0045471)
0.0 0.8 GO:0032418 lysosome localization(GO:0032418)
0.0 0.8 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 1.5 GO:0006626 protein targeting to mitochondrion(GO:0006626)
0.0 0.6 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.8 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.5 GO:0019233 sensory perception of pain(GO:0019233)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 5.7 GO:0098855 HCN channel complex(GO:0098855)
0.8 8.0 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.7 2.8 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.7 6.0 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.7 7.9 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.6 2.4 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.6 8.0 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.5 4.8 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.4 2.6 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.4 1.6 GO:1990584 cardiac Troponin complex(GO:1990584)
0.4 1.2 GO:1990075 periciliary membrane compartment(GO:1990075)
0.3 4.9 GO:0072546 ER membrane protein complex(GO:0072546)
0.3 1.3 GO:1990761 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.3 1.3 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.2 1.2 GO:0001652 granular component(GO:0001652)
0.2 1.0 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.2 1.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.2 3.5 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.2 1.5 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.2 1.7 GO:0042629 mast cell granule(GO:0042629)
0.2 2.8 GO:0035686 sperm fibrous sheath(GO:0035686)
0.2 2.1 GO:0045239 tricarboxylic acid cycle enzyme complex(GO:0045239)
0.2 0.7 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.2 1.7 GO:0071439 clathrin complex(GO:0071439)
0.2 1.2 GO:0001520 outer dense fiber(GO:0001520)
0.2 0.8 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.1 16.1 GO:0016605 PML body(GO:0016605)
0.1 0.4 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.1 2.8 GO:0032279 asymmetric synapse(GO:0032279)
0.1 5.8 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 0.7 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 0.4 GO:0072534 perineuronal net(GO:0072534)
0.1 1.8 GO:0031083 BLOC-1 complex(GO:0031083)
0.1 1.1 GO:0046930 pore complex(GO:0046930)
0.1 1.4 GO:1990635 proximal dendrite(GO:1990635)
0.1 6.1 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 0.6 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.1 7.1 GO:0000786 nucleosome(GO:0000786)
0.1 9.7 GO:0044455 mitochondrial membrane part(GO:0044455)
0.1 3.0 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 4.0 GO:0008180 COP9 signalosome(GO:0008180)
0.1 0.4 GO:0097226 sperm mitochondrial sheath(GO:0097226)
0.1 1.0 GO:0030057 desmosome(GO:0030057)
0.1 0.8 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 0.5 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 6.9 GO:0005604 basement membrane(GO:0005604)
0.1 0.8 GO:0005687 U4 snRNP(GO:0005687)
0.1 0.4 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 2.8 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 1.2 GO:0000145 exocyst(GO:0000145)
0.1 14.2 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.1 0.4 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.1 1.2 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.5 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.8 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.6 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.4 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.4 GO:0090533 cation-transporting ATPase complex(GO:0090533)
0.0 7.5 GO:0043209 myelin sheath(GO:0043209)
0.0 1.1 GO:0051233 spindle midzone(GO:0051233)
0.0 2.5 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.5 GO:1904115 axon cytoplasm(GO:1904115)
0.0 0.5 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 3.1 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 1.1 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 1.9 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 3.1 GO:0005884 actin filament(GO:0005884)
0.0 1.6 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 0.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.8 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.4 GO:0032420 stereocilium(GO:0032420)
0.0 2.4 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.3 GO:0002102 podosome(GO:0002102)
0.0 0.0 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 0.4 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 2.1 GO:0019898 extrinsic component of membrane(GO:0019898)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 8.9 GO:0004111 creatine kinase activity(GO:0004111)
1.4 5.7 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
1.2 3.6 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
1.0 4.0 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
1.0 3.0 GO:0031403 lithium ion binding(GO:0031403)
1.0 3.8 GO:0001847 opsonin receptor activity(GO:0001847)
0.9 2.8 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.9 2.8 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.8 3.2 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.7 5.9 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.7 15.0 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.6 1.9 GO:0043758 acetate-CoA ligase (ADP-forming) activity(GO:0043758)
0.6 10.7 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.6 4.3 GO:0015288 porin activity(GO:0015288)
0.6 1.8 GO:0015182 L-asparagine transmembrane transporter activity(GO:0015182)
0.6 3.9 GO:0016018 cyclosporin A binding(GO:0016018)
0.5 1.6 GO:0030172 troponin C binding(GO:0030172)
0.5 1.6 GO:0008515 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.5 2.0 GO:0004064 arylesterase activity(GO:0004064)
0.5 1.5 GO:0004962 endothelin receptor activity(GO:0004962)
0.5 3.4 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609) heterotrimeric G-protein binding(GO:0032795)
0.5 1.4 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.5 1.9 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.5 1.4 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.4 4.2 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.4 1.1 GO:0035939 microsatellite binding(GO:0035939)
0.3 1.3 GO:0008967 phosphoglycolate phosphatase activity(GO:0008967)
0.3 1.1 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.2 1.0 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.2 0.7 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.2 0.7 GO:0004743 pyruvate kinase activity(GO:0004743)
0.2 1.4 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.2 1.1 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2 2.8 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.2 1.5 GO:0015266 protein channel activity(GO:0015266)
0.2 4.7 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.2 1.0 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.2 1.2 GO:0033142 progesterone receptor binding(GO:0033142)
0.2 0.6 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.2 0.8 GO:2001069 glycogen binding(GO:2001069)
0.2 3.7 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.2 0.6 GO:0070052 collagen V binding(GO:0070052)
0.2 3.7 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.2 0.7 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.2 1.2 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.2 2.2 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.2 3.5 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.1 0.4 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 2.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 1.5 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.1 2.8 GO:0009055 electron carrier activity(GO:0009055)
0.1 1.7 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.3 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.1 2.6 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 1.0 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 7.6 GO:0005518 collagen binding(GO:0005518)
0.1 1.4 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.1 1.9 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 0.4 GO:0070012 oligopeptidase activity(GO:0070012)
0.1 1.9 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 1.5 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.1 0.8 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 0.6 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1 1.6 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 0.8 GO:1990446 U1 snRNP binding(GO:1990446)
0.1 10.4 GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
0.1 0.8 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.1 2.2 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 0.8 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 1.8 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 1.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 1.3 GO:0048156 tau protein binding(GO:0048156)
0.1 2.4 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 1.1 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 2.8 GO:0020037 heme binding(GO:0020037)
0.0 1.9 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 1.0 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.4 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 1.2 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 1.9 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.9 GO:0042165 neurotransmitter binding(GO:0042165)
0.0 11.6 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.5 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.2 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 0.3 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0 0.1 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.0 1.0 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 1.2 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 1.4 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.2 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.4 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 5.8 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.4 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.7 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.2 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.9 GO:0008198 ferrous iron binding(GO:0008198)
0.0 1.3 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.5 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 1.1 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.0 0.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 1.1 GO:0005507 copper ion binding(GO:0005507)
0.0 0.9 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.9 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 0.8 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 2.7 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 1.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.4 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 2.4 GO:0008168 methyltransferase activity(GO:0008168)
0.0 0.3 GO:0008009 chemokine activity(GO:0008009)
0.0 1.2 GO:0008201 heparin binding(GO:0008201)
0.0 0.2 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.4 GO:0001671 ATPase activator activity(GO:0001671)
0.0 2.9 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 0.5 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.5 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 12.0 PID_RAS_PATHWAY Regulation of Ras family activation
0.2 4.6 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 1.1 ST_INTERFERON_GAMMA_PATHWAY Interferon gamma pathway.
0.1 3.6 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 3.5 PID_INSULIN_PATHWAY Insulin Pathway
0.0 4.1 PID_HDAC_CLASSI_PATHWAY Signaling events mediated by HDAC Class I
0.0 3.2 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.3 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.7 PID_VEGFR1_PATHWAY VEGFR1 specific signals
0.0 1.8 PID_ENDOTHELIN_PATHWAY Endothelins
0.0 1.5 PID_EPHB_FWD_PATHWAY EPHB forward signaling
0.0 3.5 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.7 PID_ARF6_PATHWAY Arf6 signaling events
0.0 0.7 PID_HIV_NEF_PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 1.0 PID_FGF_PATHWAY FGF signaling pathway
0.0 1.3 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.0 2.5 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.8 PID_LKB1_PATHWAY LKB1 signaling events
0.0 0.4 PID_CD8_TCR_PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.6 PID_MTOR_4PATHWAY mTOR signaling pathway
0.0 0.3 PID_P38_ALPHA_BETA_PATHWAY Regulation of p38-alpha and p38-beta
0.0 1.4 PID_ERBB1_DOWNSTREAM_PATHWAY ErbB1 downstream signaling
0.0 0.4 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 5.6 REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.4 36.1 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT_ATP_SYNTHESIS_BY_CHEMIOSMOTIC_COUPLING_AND_HEAT_PRODUCTION_BY_UNCOUPLING_PROTEINS_ Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.4 12.8 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.3 3.4 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.3 3.4 REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.2 2.4 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.2 8.4 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.2 1.4 REACTOME_FGFR4_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.1 4.7 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.1 1.3 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 1.1 REACTOME_PYRIMIDINE_CATABOLISM Genes involved in Pyrimidine catabolism
0.1 2.7 REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1 3.9 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.1 2.2 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 0.6 REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 2.8 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.1 2.6 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.1 0.9 REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 1.9 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.1 1.2 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 5.7 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 0.4 REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 0.8 REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1 1.7 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 1.6 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.1 6.5 REACTOME_POTASSIUM_CHANNELS Genes involved in Potassium Channels
0.1 0.7 REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 1.3 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.0 1.4 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 1.8 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 3.0 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.6 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.0 1.5 REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.4 REACTOME_KERATAN_SULFATE_DEGRADATION Genes involved in Keratan sulfate degradation
0.0 3.1 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 2.3 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.1 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.0 0.6 REACTOME_PYRUVATE_METABOLISM Genes involved in Pyruvate metabolism
0.0 0.5 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.2 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 1.1 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 0.6 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.0 0.7 REACTOME_G_ALPHA_I_SIGNALLING_EVENTS Genes involved in G alpha (i) signalling events