Motif ID: Obox1
Z-value: 0.739
Transcription factors associated with Obox1:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Obox1 | ENSMUSG00000054310.10 | Obox1 |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.0 | 3.8 | GO:1901475 | pyruvate transmembrane transport(GO:1901475) |
| 0.8 | 2.5 | GO:0015747 | urate transport(GO:0015747) |
| 0.8 | 4.9 | GO:0060012 | synaptic transmission, glycinergic(GO:0060012) |
| 0.8 | 3.0 | GO:0001692 | histamine metabolic process(GO:0001692) imidazole-containing compound catabolic process(GO:0052805) |
| 0.6 | 4.3 | GO:0019532 | oxalate transport(GO:0019532) |
| 0.6 | 4.2 | GO:0098909 | regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909) |
| 0.6 | 2.3 | GO:0006478 | peptidyl-tyrosine sulfation(GO:0006478) |
| 0.6 | 7.3 | GO:0099628 | receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628) |
| 0.5 | 2.7 | GO:1902031 | regulation of NADP metabolic process(GO:1902031) |
| 0.4 | 2.4 | GO:1902998 | macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998) |
| 0.4 | 5.0 | GO:0000463 | maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) |
| 0.3 | 2.1 | GO:0035356 | cellular triglyceride homeostasis(GO:0035356) |
| 0.3 | 1.0 | GO:0042823 | pyridoxal phosphate biosynthetic process(GO:0042823) |
| 0.3 | 0.9 | GO:0046104 | thymidine metabolic process(GO:0046104) |
| 0.3 | 1.5 | GO:0043985 | histone H4-R3 methylation(GO:0043985) |
| 0.3 | 3.9 | GO:0097186 | amelogenesis(GO:0097186) |
| 0.3 | 1.2 | GO:0072531 | pyrimidine-containing compound transmembrane transport(GO:0072531) |
| 0.3 | 1.5 | GO:0060398 | regulation of growth hormone receptor signaling pathway(GO:0060398) |
| 0.3 | 1.4 | GO:1903527 | positive regulation of membrane tubulation(GO:1903527) |
| 0.3 | 1.2 | GO:0044861 | protein transport into plasma membrane raft(GO:0044861) |
| 0.3 | 3.1 | GO:0097113 | AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688) |
| 0.3 | 2.2 | GO:0051534 | negative regulation of NFAT protein import into nucleus(GO:0051534) |
| 0.3 | 0.8 | GO:0031990 | mRNA export from nucleus in response to heat stress(GO:0031990) |
| 0.3 | 2.6 | GO:0030388 | fructose 6-phosphate metabolic process(GO:0006002) fructose 1,6-bisphosphate metabolic process(GO:0030388) |
| 0.3 | 0.8 | GO:0002182 | cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248) |
| 0.2 | 1.7 | GO:0006369 | termination of RNA polymerase II transcription(GO:0006369) |
| 0.2 | 1.0 | GO:0090472 | dibasic protein processing(GO:0090472) |
| 0.2 | 0.9 | GO:2000182 | regulation of progesterone biosynthetic process(GO:2000182) |
| 0.2 | 1.7 | GO:0030223 | neutrophil differentiation(GO:0030223) |
| 0.2 | 2.5 | GO:1900383 | regulation of synaptic plasticity by receptor localization to synapse(GO:1900383) |
| 0.2 | 0.8 | GO:2000110 | protein sialylation(GO:1990743) negative regulation of macrophage apoptotic process(GO:2000110) |
| 0.2 | 3.4 | GO:0031340 | positive regulation of vesicle fusion(GO:0031340) |
| 0.2 | 2.6 | GO:0010447 | response to acidic pH(GO:0010447) |
| 0.2 | 1.0 | GO:0016266 | O-glycan processing(GO:0016266) |
| 0.2 | 0.5 | GO:1902396 | protein localization to bicellular tight junction(GO:1902396) |
| 0.2 | 1.3 | GO:0070813 | hydrogen sulfide metabolic process(GO:0070813) |
| 0.2 | 0.7 | GO:0032237 | activation of store-operated calcium channel activity(GO:0032237) |
| 0.2 | 0.6 | GO:0006244 | pyrimidine nucleotide catabolic process(GO:0006244) pyrimidine deoxyribonucleotide catabolic process(GO:0009223) |
| 0.1 | 2.6 | GO:0046069 | cGMP catabolic process(GO:0046069) |
| 0.1 | 1.0 | GO:0008272 | sulfate transport(GO:0008272) |
| 0.1 | 0.7 | GO:0006689 | ganglioside catabolic process(GO:0006689) |
| 0.1 | 0.9 | GO:2000002 | negative regulation of DNA damage checkpoint(GO:2000002) |
| 0.1 | 0.5 | GO:1900150 | neutrophil mediated cytotoxicity(GO:0070942) neutrophil mediated killing of symbiont cell(GO:0070943) regulation of defense response to fungus(GO:1900150) |
| 0.1 | 0.5 | GO:0060155 | platelet dense granule organization(GO:0060155) |
| 0.1 | 4.8 | GO:0051491 | positive regulation of filopodium assembly(GO:0051491) |
| 0.1 | 7.2 | GO:0042771 | intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771) |
| 0.1 | 2.3 | GO:0007095 | mitotic G2 DNA damage checkpoint(GO:0007095) |
| 0.1 | 0.3 | GO:0032596 | protein transport into membrane raft(GO:0032596) |
| 0.1 | 0.9 | GO:2001268 | negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268) |
| 0.1 | 1.6 | GO:0010818 | T cell chemotaxis(GO:0010818) |
| 0.1 | 0.4 | GO:2001023 | regulation of response to drug(GO:2001023) |
| 0.1 | 2.7 | GO:0015804 | neutral amino acid transport(GO:0015804) |
| 0.1 | 1.0 | GO:0014029 | neural crest formation(GO:0014029) |
| 0.1 | 1.9 | GO:0006622 | protein targeting to lysosome(GO:0006622) |
| 0.1 | 0.6 | GO:0021539 | subthalamus development(GO:0021539) |
| 0.1 | 0.3 | GO:1904049 | negative regulation of spontaneous neurotransmitter secretion(GO:1904049) |
| 0.1 | 1.7 | GO:2000310 | regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310) |
| 0.1 | 0.7 | GO:0042167 | porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149) |
| 0.1 | 0.4 | GO:0050747 | positive regulation of lipoprotein metabolic process(GO:0050747) |
| 0.1 | 1.6 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
| 0.1 | 0.5 | GO:0060136 | embryonic process involved in female pregnancy(GO:0060136) |
| 0.1 | 0.2 | GO:0052428 | modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428) |
| 0.1 | 0.7 | GO:0090503 | RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503) |
| 0.1 | 5.0 | GO:1903749 | positive regulation of establishment of protein localization to mitochondrion(GO:1903749) positive regulation of protein targeting to mitochondrion(GO:1903955) |
| 0.1 | 0.8 | GO:0090435 | protein localization to nuclear envelope(GO:0090435) |
| 0.1 | 1.4 | GO:0035987 | endodermal cell differentiation(GO:0035987) |
| 0.1 | 0.4 | GO:0006685 | sphingomyelin catabolic process(GO:0006685) |
| 0.1 | 1.5 | GO:0043171 | peptide catabolic process(GO:0043171) |
| 0.1 | 0.2 | GO:0006642 | triglyceride mobilization(GO:0006642) oncostatin-M-mediated signaling pathway(GO:0038165) |
| 0.1 | 0.2 | GO:0006543 | glutamine catabolic process(GO:0006543) |
| 0.1 | 0.3 | GO:0018002 | N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920) |
| 0.1 | 2.5 | GO:0050919 | negative chemotaxis(GO:0050919) |
| 0.1 | 0.2 | GO:0042373 | vitamin K metabolic process(GO:0042373) |
| 0.1 | 0.4 | GO:0000055 | ribosomal large subunit export from nucleus(GO:0000055) |
| 0.1 | 0.6 | GO:1903894 | regulation of IRE1-mediated unfolded protein response(GO:1903894) |
| 0.1 | 0.4 | GO:0045324 | late endosome to vacuole transport(GO:0045324) |
| 0.0 | 0.2 | GO:0007197 | adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207) |
| 0.0 | 0.6 | GO:0046036 | CTP biosynthetic process(GO:0006241) CTP metabolic process(GO:0046036) |
| 0.0 | 1.2 | GO:0071108 | protein K48-linked deubiquitination(GO:0071108) |
| 0.0 | 0.8 | GO:0031998 | regulation of fatty acid beta-oxidation(GO:0031998) |
| 0.0 | 0.3 | GO:0016255 | attachment of GPI anchor to protein(GO:0016255) |
| 0.0 | 0.3 | GO:0046007 | negative regulation of activated T cell proliferation(GO:0046007) |
| 0.0 | 1.1 | GO:0000027 | ribosomal large subunit assembly(GO:0000027) |
| 0.0 | 1.5 | GO:0008333 | endosome to lysosome transport(GO:0008333) |
| 0.0 | 0.1 | GO:0051593 | response to folic acid(GO:0051593) |
| 0.0 | 0.2 | GO:0098706 | ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706) |
| 0.0 | 3.0 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
| 0.0 | 0.2 | GO:0097680 | double-strand break repair via classical nonhomologous end joining(GO:0097680) |
| 0.0 | 0.7 | GO:0001829 | trophectodermal cell differentiation(GO:0001829) |
| 0.0 | 1.8 | GO:0080171 | lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171) |
| 0.0 | 0.4 | GO:0006353 | DNA-templated transcription, termination(GO:0006353) |
| 0.0 | 2.2 | GO:0045454 | cell redox homeostasis(GO:0045454) |
| 0.0 | 0.1 | GO:0071550 | death-inducing signaling complex assembly(GO:0071550) |
| 0.0 | 0.8 | GO:0043550 | regulation of lipid kinase activity(GO:0043550) |
| 0.0 | 0.9 | GO:0006783 | heme biosynthetic process(GO:0006783) |
| 0.0 | 1.0 | GO:0000387 | spliceosomal snRNP assembly(GO:0000387) |
| 0.0 | 2.4 | GO:0009566 | fertilization(GO:0009566) |
| 0.0 | 3.9 | GO:0035023 | regulation of Rho protein signal transduction(GO:0035023) |
| 0.0 | 3.9 | GO:0031032 | actomyosin structure organization(GO:0031032) |
| 0.0 | 0.7 | GO:0097484 | dendrite extension(GO:0097484) |
| 0.0 | 0.1 | GO:0019369 | arachidonic acid metabolic process(GO:0019369) |
| 0.0 | 0.1 | GO:0002862 | negative regulation of inflammatory response to antigenic stimulus(GO:0002862) |
| 0.0 | 3.9 | GO:0048839 | inner ear development(GO:0048839) |
| 0.0 | 0.8 | GO:0007029 | endoplasmic reticulum organization(GO:0007029) |
| 0.0 | 1.0 | GO:0046324 | regulation of glucose import(GO:0046324) |
| 0.0 | 0.4 | GO:0044458 | motile cilium assembly(GO:0044458) axonemal dynein complex assembly(GO:0070286) |
| 0.0 | 1.1 | GO:0048747 | muscle fiber development(GO:0048747) |
| 0.0 | 0.9 | GO:0035065 | regulation of histone acetylation(GO:0035065) |
| 0.0 | 5.1 | GO:0018105 | peptidyl-serine phosphorylation(GO:0018105) |
| 0.0 | 2.0 | GO:0006633 | fatty acid biosynthetic process(GO:0006633) |
| 0.0 | 0.2 | GO:0071578 | zinc II ion transmembrane import(GO:0071578) |
| 0.0 | 0.2 | GO:0030150 | protein import into mitochondrial matrix(GO:0030150) |
| 0.0 | 1.6 | GO:0006413 | translational initiation(GO:0006413) |
| 0.0 | 0.3 | GO:0002021 | response to dietary excess(GO:0002021) |
| 0.0 | 3.1 | GO:0006869 | lipid transport(GO:0006869) |
| 0.0 | 1.7 | GO:0007416 | synapse assembly(GO:0007416) |
| 0.0 | 0.0 | GO:0010958 | regulation of amino acid import(GO:0010958) |
| 0.0 | 2.0 | GO:0006457 | protein folding(GO:0006457) |
| 0.0 | 4.9 | GO:0007186 | G-protein coupled receptor signaling pathway(GO:0007186) |
| 0.0 | 0.5 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
| 0.0 | 0.9 | GO:0006888 | ER to Golgi vesicle-mediated transport(GO:0006888) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 2.6 | GO:0005945 | 6-phosphofructokinase complex(GO:0005945) |
| 0.5 | 5.0 | GO:0070545 | PeBoW complex(GO:0070545) |
| 0.4 | 3.5 | GO:0002177 | manchette(GO:0002177) |
| 0.4 | 7.3 | GO:0044224 | juxtaparanode region of axon(GO:0044224) |
| 0.3 | 2.4 | GO:0034366 | spherical high-density lipoprotein particle(GO:0034366) |
| 0.3 | 1.0 | GO:0014802 | terminal cisterna(GO:0014802) |
| 0.3 | 2.5 | GO:0034709 | methylosome(GO:0034709) |
| 0.2 | 8.5 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.2 | 1.2 | GO:0044352 | pinosome(GO:0044352) macropinosome(GO:0044354) |
| 0.2 | 0.5 | GO:0045009 | melanosome membrane(GO:0033162) chitosome(GO:0045009) |
| 0.1 | 1.9 | GO:0044754 | autolysosome(GO:0044754) |
| 0.1 | 4.4 | GO:0034707 | chloride channel complex(GO:0034707) |
| 0.1 | 0.9 | GO:0032541 | cortical endoplasmic reticulum(GO:0032541) |
| 0.1 | 1.7 | GO:0005847 | mRNA cleavage and polyadenylation specificity factor complex(GO:0005847) |
| 0.1 | 0.9 | GO:0000347 | THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445) |
| 0.1 | 3.1 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
| 0.1 | 0.8 | GO:0000138 | Golgi trans cisterna(GO:0000138) |
| 0.1 | 2.4 | GO:0097440 | apical dendrite(GO:0097440) |
| 0.1 | 0.8 | GO:0043240 | Fanconi anaemia nuclear complex(GO:0043240) |
| 0.1 | 1.4 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) |
| 0.1 | 0.7 | GO:0042582 | primary lysosome(GO:0005766) azurophil granule(GO:0042582) |
| 0.1 | 1.0 | GO:0012510 | trans-Golgi network transport vesicle membrane(GO:0012510) |
| 0.1 | 0.9 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
| 0.1 | 0.3 | GO:1990761 | growth cone lamellipodium(GO:1990761) |
| 0.1 | 0.2 | GO:0005896 | interleukin-6 receptor complex(GO:0005896) |
| 0.1 | 1.6 | GO:0030686 | 90S preribosome(GO:0030686) |
| 0.1 | 2.8 | GO:0031941 | filamentous actin(GO:0031941) |
| 0.1 | 4.2 | GO:0014704 | intercalated disc(GO:0014704) |
| 0.0 | 0.8 | GO:0033655 | host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655) |
| 0.0 | 0.6 | GO:0031143 | pseudopodium(GO:0031143) |
| 0.0 | 3.9 | GO:0005905 | clathrin-coated pit(GO:0005905) |
| 0.0 | 0.3 | GO:0042765 | GPI-anchor transamidase complex(GO:0042765) |
| 0.0 | 3.2 | GO:0005811 | lipid particle(GO:0005811) |
| 0.0 | 0.4 | GO:0000815 | ESCRT III complex(GO:0000815) |
| 0.0 | 1.4 | GO:0002102 | podosome(GO:0002102) |
| 0.0 | 1.5 | GO:0031902 | late endosome membrane(GO:0031902) |
| 0.0 | 1.0 | GO:0009897 | external side of plasma membrane(GO:0009897) |
| 0.0 | 1.8 | GO:0030136 | clathrin-coated vesicle(GO:0030136) |
| 0.0 | 1.3 | GO:0016592 | mediator complex(GO:0016592) |
| 0.0 | 0.3 | GO:0031415 | NatA complex(GO:0031415) |
| 0.0 | 0.2 | GO:0070876 | SOSS complex(GO:0070876) |
| 0.0 | 1.2 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
| 0.0 | 0.2 | GO:0005744 | mitochondrial inner membrane presequence translocase complex(GO:0005744) |
| 0.0 | 0.2 | GO:0098984 | asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984) |
| 0.0 | 0.3 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
| 0.0 | 0.4 | GO:0005666 | DNA-directed RNA polymerase III complex(GO:0005666) |
| 0.0 | 2.7 | GO:0005770 | late endosome(GO:0005770) |
| 0.0 | 4.6 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 0.0 | 2.6 | GO:0043204 | perikaryon(GO:0043204) |
| 0.0 | 1.7 | GO:0005604 | basement membrane(GO:0005604) |
| 0.0 | 1.1 | GO:0000315 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
| 0.0 | 7.8 | GO:0005635 | nuclear envelope(GO:0005635) |
| 0.0 | 0.4 | GO:0031526 | brush border membrane(GO:0031526) |
| 0.0 | 1.0 | GO:0005793 | endoplasmic reticulum-Golgi intermediate compartment(GO:0005793) |
| 0.0 | 0.5 | GO:0000314 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
| 0.0 | 12.7 | GO:0005887 | integral component of plasma membrane(GO:0005887) |
| 0.0 | 0.2 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.0 | 2.5 | GO:0045211 | postsynaptic membrane(GO:0045211) |
| 0.0 | 0.6 | GO:0008180 | COP9 signalosome(GO:0008180) |
| 0.0 | 2.0 | GO:0005840 | ribosome(GO:0005840) |
| 0.0 | 0.1 | GO:0098827 | endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827) |
| 0.0 | 0.3 | GO:0030315 | T-tubule(GO:0030315) |
| 0.0 | 0.2 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
| 0.0 | 0.1 | GO:0019773 | proteasome core complex, alpha-subunit complex(GO:0019773) |
| 0.0 | 0.7 | GO:0043195 | terminal bouton(GO:0043195) |
| 0.0 | 0.0 | GO:0031533 | mRNA cap methyltransferase complex(GO:0031533) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.6 | 4.9 | GO:0016934 | extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934) |
| 1.0 | 3.8 | GO:0050833 | pyruvate transmembrane transporter activity(GO:0050833) |
| 0.9 | 7.3 | GO:0031811 | G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812) |
| 0.9 | 2.7 | GO:0004473 | malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473) |
| 0.9 | 2.6 | GO:0003858 | 3-hydroxybutyrate dehydrogenase activity(GO:0003858) |
| 0.7 | 2.1 | GO:0003846 | 2-acylglycerol O-acyltransferase activity(GO:0003846) |
| 0.6 | 2.6 | GO:0003872 | 6-phosphofructokinase activity(GO:0003872) |
| 0.6 | 2.5 | GO:0015143 | urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702) |
| 0.6 | 2.3 | GO:0008476 | protein-tyrosine sulfotransferase activity(GO:0008476) |
| 0.4 | 2.2 | GO:0008273 | calcium, potassium:sodium antiporter activity(GO:0008273) |
| 0.4 | 7.7 | GO:0031681 | G-protein beta-subunit binding(GO:0031681) |
| 0.4 | 3.7 | GO:0035374 | chondroitin sulfate binding(GO:0035374) |
| 0.4 | 1.6 | GO:0035243 | protein-arginine omega-N symmetric methyltransferase activity(GO:0035243) |
| 0.4 | 4.3 | GO:0019531 | secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531) |
| 0.4 | 2.6 | GO:0004118 | cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) |
| 0.3 | 1.0 | GO:0015038 | glutathione disulfide oxidoreductase activity(GO:0015038) |
| 0.3 | 1.0 | GO:0001042 | RNA polymerase I core binding(GO:0001042) |
| 0.3 | 2.7 | GO:0019534 | toxin transporter activity(GO:0019534) |
| 0.3 | 1.2 | GO:0005459 | UDP-galactose transmembrane transporter activity(GO:0005459) |
| 0.3 | 0.9 | GO:0050510 | N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510) |
| 0.3 | 2.4 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
| 0.2 | 0.9 | GO:0019136 | deoxynucleoside kinase activity(GO:0019136) |
| 0.2 | 1.0 | GO:0042285 | UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285) |
| 0.2 | 1.2 | GO:0019784 | NEDD8-specific protease activity(GO:0019784) |
| 0.2 | 1.7 | GO:0008420 | CTD phosphatase activity(GO:0008420) |
| 0.2 | 1.5 | GO:0019869 | chloride channel inhibitor activity(GO:0019869) |
| 0.2 | 1.6 | GO:0005041 | low-density lipoprotein receptor activity(GO:0005041) |
| 0.2 | 0.8 | GO:0003835 | beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835) |
| 0.2 | 0.7 | GO:0004074 | biliverdin reductase activity(GO:0004074) |
| 0.2 | 0.5 | GO:0035651 | AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651) |
| 0.2 | 5.3 | GO:0043394 | proteoglycan binding(GO:0043394) |
| 0.2 | 0.6 | GO:0003883 | CTP synthase activity(GO:0003883) |
| 0.1 | 3.9 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 0.1 | 2.2 | GO:0030346 | protein phosphatase 2B binding(GO:0030346) |
| 0.1 | 3.4 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.1 | 0.7 | GO:0004563 | beta-N-acetylhexosaminidase activity(GO:0004563) |
| 0.1 | 1.3 | GO:0016701 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702) |
| 0.1 | 4.2 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
| 0.1 | 4.8 | GO:0001786 | phosphatidylserine binding(GO:0001786) |
| 0.1 | 1.0 | GO:1990446 | U1 snRNP binding(GO:1990446) |
| 0.1 | 3.8 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.1 | 2.4 | GO:0051787 | misfolded protein binding(GO:0051787) |
| 0.1 | 0.3 | GO:0034714 | type III transforming growth factor beta receptor binding(GO:0034714) |
| 0.1 | 1.0 | GO:0048406 | nerve growth factor binding(GO:0048406) |
| 0.1 | 1.0 | GO:0010181 | FMN binding(GO:0010181) |
| 0.1 | 2.4 | GO:0043539 | protein serine/threonine kinase activator activity(GO:0043539) |
| 0.1 | 1.0 | GO:0070008 | serine-type exopeptidase activity(GO:0070008) |
| 0.1 | 0.4 | GO:0008429 | phosphatidylethanolamine binding(GO:0008429) |
| 0.1 | 1.8 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
| 0.1 | 1.5 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
| 0.1 | 0.6 | GO:0008121 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
| 0.1 | 0.2 | GO:0016907 | G-protein coupled acetylcholine receptor activity(GO:0016907) |
| 0.1 | 0.2 | GO:0008823 | cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851) |
| 0.1 | 4.8 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.1 | 0.8 | GO:0035925 | mRNA 3'-UTR AU-rich region binding(GO:0035925) |
| 0.1 | 0.2 | GO:0004923 | leukemia inhibitory factor receptor activity(GO:0004923) oncostatin-M receptor activity(GO:0004924) |
| 0.1 | 0.3 | GO:1990190 | peptide-glutamate-N-acetyltransferase activity(GO:1990190) |
| 0.1 | 0.5 | GO:0001055 | RNA polymerase II activity(GO:0001055) |
| 0.1 | 1.9 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
| 0.1 | 0.2 | GO:0004090 | carbonyl reductase (NADPH) activity(GO:0004090) |
| 0.1 | 1.2 | GO:0005521 | lamin binding(GO:0005521) |
| 0.0 | 0.4 | GO:0004767 | sphingomyelin phosphodiesterase activity(GO:0004767) |
| 0.0 | 0.5 | GO:0045236 | CXCR chemokine receptor binding(GO:0045236) |
| 0.0 | 2.2 | GO:0015485 | cholesterol binding(GO:0015485) |
| 0.0 | 2.5 | GO:0046875 | ephrin receptor binding(GO:0046875) |
| 0.0 | 0.3 | GO:0004984 | olfactory receptor activity(GO:0004984) |
| 0.0 | 0.7 | GO:0015269 | calcium-activated potassium channel activity(GO:0015269) |
| 0.0 | 0.3 | GO:0003923 | GPI-anchor transamidase activity(GO:0003923) |
| 0.0 | 0.2 | GO:0004359 | glutaminase activity(GO:0004359) |
| 0.0 | 3.0 | GO:0008170 | N-methyltransferase activity(GO:0008170) |
| 0.0 | 0.6 | GO:0008253 | 5'-nucleotidase activity(GO:0008253) |
| 0.0 | 0.7 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
| 0.0 | 1.6 | GO:0005246 | calcium channel regulator activity(GO:0005246) |
| 0.0 | 1.2 | GO:0003899 | DNA-directed RNA polymerase activity(GO:0003899) |
| 0.0 | 0.4 | GO:0004000 | adenosine deaminase activity(GO:0004000) |
| 0.0 | 0.3 | GO:0008603 | cAMP-dependent protein kinase regulator activity(GO:0008603) |
| 0.0 | 1.8 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 0.0 | 0.2 | GO:0015266 | protein channel activity(GO:0015266) |
| 0.0 | 0.4 | GO:0004890 | GABA-A receptor activity(GO:0004890) |
| 0.0 | 0.3 | GO:0005537 | mannose binding(GO:0005537) |
| 0.0 | 1.7 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 0.0 | 0.8 | GO:0045182 | translation regulator activity(GO:0045182) |
| 0.0 | 0.1 | GO:0004104 | cholinesterase activity(GO:0004104) choline binding(GO:0033265) |
| 0.0 | 0.7 | GO:0035035 | histone acetyltransferase binding(GO:0035035) |
| 0.0 | 0.3 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
| 0.0 | 5.1 | GO:0005096 | GTPase activator activity(GO:0005096) |
| 0.0 | 1.9 | GO:0042626 | ATPase activity, coupled to transmembrane movement of substances(GO:0042626) |
| 0.0 | 0.7 | GO:0004693 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) |
| 0.0 | 4.3 | GO:0061630 | ubiquitin protein ligase activity(GO:0061630) |
| 0.0 | 0.4 | GO:0008198 | ferrous iron binding(GO:0008198) |
| 0.0 | 2.3 | GO:0005244 | voltage-gated ion channel activity(GO:0005244) voltage-gated channel activity(GO:0022832) |
| 0.0 | 6.1 | GO:0005509 | calcium ion binding(GO:0005509) |
| 0.0 | 0.8 | GO:0019843 | rRNA binding(GO:0019843) |
| 0.0 | 0.3 | GO:0000166 | nucleotide binding(GO:0000166) nucleoside phosphate binding(GO:1901265) |
| 0.0 | 0.3 | GO:0003725 | double-stranded RNA binding(GO:0003725) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 8.5 | PID_THROMBIN_PAR4_PATHWAY | PAR4-mediated thrombin signaling events |
| 0.2 | 7.4 | ST_GA12_PATHWAY | G alpha 12 Pathway |
| 0.1 | 1.7 | ST_G_ALPHA_S_PATHWAY | G alpha s Pathway |
| 0.1 | 3.3 | PID_P38_MKK3_6PATHWAY | p38 MAPK signaling pathway |
| 0.1 | 3.9 | PID_CDC42_REG_PATHWAY | Regulation of CDC42 activity |
| 0.1 | 7.3 | NABA_ECM_AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.1 | 2.6 | PID_HNF3B_PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.1 | 1.4 | PID_ARF_3PATHWAY | Arf1 pathway |
| 0.0 | 1.1 | PID_HDAC_CLASSIII_PATHWAY | Signaling events mediated by HDAC Class III |
| 0.0 | 2.4 | PID_MYC_REPRESS_PATHWAY | Validated targets of C-MYC transcriptional repression |
| 0.0 | 2.4 | PID_E2F_PATHWAY | E2F transcription factor network |
| 0.0 | 1.2 | PID_LIS1_PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 0.0 | 0.6 | PID_HIF1A_PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
| 0.0 | 0.5 | PID_IL23_PATHWAY | IL23-mediated signaling events |
| 0.0 | 1.3 | PID_VEGFR1_2_PATHWAY | Signaling events mediated by VEGFR1 and VEGFR2 |
| 0.0 | 0.7 | PID_EPO_PATHWAY | EPO signaling pathway |
| 0.0 | 0.2 | PID_IL27_PATHWAY | IL27-mediated signaling events |
| 0.0 | 1.0 | PID_HIF1_TFPATHWAY | HIF-1-alpha transcription factor network |
| 0.0 | 2.2 | NABA_ECM_REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.0 | 2.7 | NABA_MATRISOME_ASSOCIATED | Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors |
| 0.0 | 0.5 | PID_DELTA_NP63_PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.0 | 0.7 | PID_LKB1_PATHWAY | LKB1 signaling events |
| 0.0 | 0.3 | PID_INTEGRIN_A4B1_PATHWAY | Alpha4 beta1 integrin signaling events |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 2.2 | REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY | Genes involved in Endosomal/Vacuolar pathway |
| 0.4 | 3.8 | REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
| 0.4 | 2.5 | REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT | Genes involved in Organic cation/anion/zwitterion transport |
| 0.3 | 10.1 | REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA | Genes involved in G beta:gamma signalling through PLC beta |
| 0.3 | 5.3 | REACTOME_LIGAND_GATED_ION_CHANNEL_TRANSPORT | Genes involved in Ligand-gated ion channel transport |
| 0.2 | 3.7 | REACTOME_CRMPS_IN_SEMA3A_SIGNALING | Genes involved in CRMPs in Sema3A signaling |
| 0.1 | 2.6 | REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS | Genes involved in ABCA transporters in lipid homeostasis |
| 0.1 | 1.6 | REACTOME_METABOLISM_OF_NON_CODING_RNA | Genes involved in Metabolism of non-coding RNA |
| 0.1 | 1.5 | REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
| 0.1 | 1.0 | REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS | Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins |
| 0.1 | 2.6 | REACTOME_CGMP_EFFECTS | Genes involved in cGMP effects |
| 0.1 | 2.7 | REACTOME_BASIGIN_INTERACTIONS | Genes involved in Basigin interactions |
| 0.1 | 2.1 | REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.1 | 1.4 | REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS | Genes involved in Viral Messenger RNA Synthesis |
| 0.1 | 0.7 | REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
| 0.1 | 0.7 | REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE | Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle |
| 0.1 | 0.7 | REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |
| 0.1 | 1.6 | REACTOME_PYRIMIDINE_METABOLISM | Genes involved in Pyrimidine metabolism |
| 0.1 | 5.6 | REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK | Genes involved in NRAGE signals death through JNK |
| 0.1 | 6.5 | REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
| 0.1 | 1.7 | REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
| 0.1 | 2.6 | REACTOME_GLYCOLYSIS | Genes involved in Glycolysis |
| 0.1 | 0.5 | REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR | Genes involved in Trafficking and processing of endosomal TLR |
| 0.1 | 1.3 | REACTOME_SULFUR_AMINO_ACID_METABOLISM | Genes involved in Sulfur amino acid metabolism |
| 0.0 | 9.6 | REACTOME_FATTY_ACID_TRIACYLGLYCEROL_AND_KETONE_BODY_METABOLISM | Genes involved in Fatty acid, triacylglycerol, and ketone body metabolism |
| 0.0 | 0.9 | REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
| 0.0 | 3.2 | REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ | Genes involved in Response to elevated platelet cytosolic Ca2+ |
| 0.0 | 1.2 | REACTOME_MRNA_SPLICING_MINOR_PATHWAY | Genes involved in mRNA Splicing - Minor Pathway |
| 0.0 | 0.8 | REACTOME_G0_AND_EARLY_G1 | Genes involved in G0 and Early G1 |
| 0.0 | 0.7 | REACTOME_METABOLISM_OF_PORPHYRINS | Genes involved in Metabolism of porphyrins |
| 0.0 | 0.8 | REACTOME_TRANSPORT_TO_THE_GOLGI_AND_SUBSEQUENT_MODIFICATION | Genes involved in Transport to the Golgi and subsequent modification |
| 0.0 | 0.4 | REACTOME_RNA_POL_III_CHAIN_ELONGATION | Genes involved in RNA Polymerase III Chain Elongation |
| 0.0 | 0.7 | REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS | Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers |
| 0.0 | 2.5 | REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION | Genes involved in Factors involved in megakaryocyte development and platelet production |
| 0.0 | 0.4 | REACTOME_SYNTHESIS_OF_PC | Genes involved in Synthesis of PC |
| 0.0 | 1.6 | REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION | Genes involved in MHC class II antigen presentation |
| 0.0 | 0.2 | REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE | Genes involved in Glutamate Neurotransmitter Release Cycle |
| 0.0 | 0.2 | REACTOME_IL_6_SIGNALING | Genes involved in Interleukin-6 signaling |
| 0.0 | 1.0 | REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
| 0.0 | 0.4 | REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT | Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT) |
| 0.0 | 0.4 | REACTOME_GLYCOSPHINGOLIPID_METABOLISM | Genes involved in Glycosphingolipid metabolism |
