Motif ID: Obox3

Z-value: 0.402


Transcription factors associated with Obox3:

Gene SymbolEntrez IDGene Name
Obox3 ENSMUSG00000066772.6 Obox3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Obox3mm10_v2_chr7_-_15627876_156278760.065.8e-01Click!


Activity profile for motif Obox3.

activity profile for motif Obox3


Sorted Z-values histogram for motif Obox3

Sorted Z-values for motif Obox3



Network of associatons between targets according to the STRING database.



First level regulatory network of Obox3

PNG image of the network

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Top targets:


Showing 1 to 20 of 54 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_+_74013442 2.156 ENSMUST00000098006.2
ENSMUST00000084474.5
Frmd3

FERM domain containing 3

chr1_+_140246216 1.850 ENSMUST00000119786.1
ENSMUST00000120796.1
ENSMUST00000060201.8
ENSMUST00000120709.1
Kcnt2



potassium channel, subfamily T, member 2



chr14_-_19977040 1.757 ENSMUST00000159028.1
Gng2
guanine nucleotide binding protein (G protein), gamma 2
chr14_-_19977151 1.717 ENSMUST00000055100.7
ENSMUST00000162425.1
Gng2

guanine nucleotide binding protein (G protein), gamma 2

chr14_-_19977249 1.626 ENSMUST00000160013.1
Gng2
guanine nucleotide binding protein (G protein), gamma 2
chr14_+_61138445 1.481 ENSMUST00000089394.3
ENSMUST00000119509.1
Sacs

sacsin

chr2_+_136892168 1.469 ENSMUST00000099311.2
Slx4ip
SLX4 interacting protein
chr6_+_4902913 1.456 ENSMUST00000175889.1
ENSMUST00000168998.2
Ppp1r9a

protein phosphatase 1, regulatory (inhibitor) subunit 9A

chr13_-_23369156 1.424 ENSMUST00000125328.1
ENSMUST00000145451.1
ENSMUST00000050101.2
Zfp322a


zinc finger protein 322A


chr19_+_3767397 1.393 ENSMUST00000113974.4
ENSMUST00000113972.2
ENSMUST00000113973.1
ENSMUST00000113977.2
ENSMUST00000052699.6
ENSMUST00000113968.2
Suv420h1





suppressor of variegation 4-20 homolog 1 (Drosophila)





chr1_-_52232296 1.298 ENSMUST00000114512.1
Gls
glutaminase
chr7_-_103843154 1.167 ENSMUST00000063957.4
Hbb-bh1
hemoglobin Z, beta-like embryonic chain
chr1_-_133701881 1.160 ENSMUST00000167348.1
Gm17678
predicted gene, 17678
chr14_-_69805524 1.147 ENSMUST00000022665.2
Rhobtb2
Rho-related BTB domain containing 2
chr6_-_91807424 1.077 ENSMUST00000162300.1
Grip2
glutamate receptor interacting protein 2
chr4_+_115000174 1.054 ENSMUST00000129957.1
Stil
Scl/Tal1 interrupting locus
chr1_+_118389058 1.016 ENSMUST00000049404.6
ENSMUST00000070989.7
ENSMUST00000165223.1
ENSMUST00000178710.1
Clasp1



CLIP associating protein 1



chr2_+_69722797 0.993 ENSMUST00000090858.3
Ppig
peptidyl-prolyl isomerase G (cyclophilin G)
chr10_+_111972664 0.987 ENSMUST00000163048.1
ENSMUST00000174653.1
Krr1

KRR1, small subunit (SSU) processome component, homolog (yeast)

chr7_-_4752972 0.985 ENSMUST00000183971.1
ENSMUST00000182173.1
ENSMUST00000182738.1
ENSMUST00000184143.1
ENSMUST00000182111.1
ENSMUST00000182048.1
ENSMUST00000063324.7
Cox6b2






cytochrome c oxidase subunit VIb polypeptide 2







Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 16 of 16 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 2.0 GO:0014824 artery smooth muscle contraction(GO:0014824)
0.0 1.9 GO:0071805 potassium ion transmembrane transport(GO:0071805)
0.2 1.8 GO:0033504 floor plate development(GO:0033504)
0.5 1.5 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.3 1.3 GO:0006543 glutamine catabolic process(GO:0006543)
0.2 1.2 GO:0015671 oxygen transport(GO:0015671)
0.1 1.0 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 1.0 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 1.0 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.1 0.8 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.1 0.8 GO:0010818 T cell chemotaxis(GO:0010818)
0.0 0.8 GO:0051764 actin crosslink formation(GO:0051764)
0.2 0.5 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.0 0.5 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.1 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0 0.1 GO:0014029 neural crest formation(GO:0014029)

Gene overrepresentation in cellular_component category:

Showing 1 to 14 of 14 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 2.7 GO:0016363 nuclear matrix(GO:0016363)
0.0 2.0 GO:0043198 dendritic shaft(GO:0043198)
0.0 1.9 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 1.6 GO:0005814 centriole(GO:0005814)
0.3 1.5 GO:1990761 growth cone lamellipodium(GO:1990761)
0.1 1.2 GO:0005833 hemoglobin complex(GO:0005833)
0.3 1.0 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.1 1.0 GO:0030061 mitochondrial crista(GO:0030061)
0.0 1.0 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.8 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.8 GO:0031941 filamentous actin(GO:0031941)
0.0 0.5 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.5 GO:0030131 clathrin adaptor complex(GO:0030131)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 21 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 5.1 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 2.2 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 2.0 GO:0035254 glutamate receptor binding(GO:0035254)
0.1 1.9 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 1.5 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 1.5 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.3 1.3 GO:0004359 glutaminase activity(GO:0004359)
0.3 1.2 GO:0031721 hemoglobin alpha binding(GO:0031721)
0.2 1.0 GO:0043515 kinetochore binding(GO:0043515)
0.0 1.0 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.9 GO:0070064 proline-rich region binding(GO:0070064)
0.1 0.8 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.1 0.8 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.8 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454) histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 0.7 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.2 0.5 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.0 0.5 GO:0050699 WW domain binding(GO:0050699)
0.0 0.3 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.1 GO:0001042 RNA polymerase I core binding(GO:0001042)

Gene overrepresentation in C2:CP category:

Showing 1 to 5 of 5 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 5.1 PID_THROMBIN_PAR4_PATHWAY PAR4-mediated thrombin signaling events
0.0 3.0 PID_REG_GR_PATHWAY Glucocorticoid receptor regulatory network
0.1 1.8 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.8 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.5 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 8 of 8 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 5.1 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA Genes involved in G beta:gamma signalling through PLC beta
0.1 2.0 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 1.3 REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 1.0 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.8 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.8 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.5 REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.5 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression