---

Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr6_-_23248264	45.217	ENSMUST00000031709.5	Fezf1	Fez family zinc finger 1
chr14_+_68083853	20.675	ENSMUST00000022639.7	Nefl	neurofilament, light polypeptide
chr10_-_64090241	20.539	ENSMUST00000133588.1	Lrrtm3	leucine rich repeat transmembrane neuronal 3
chr10_-_64090265	19.904	ENSMUST00000105439.1	Lrrtm3	leucine rich repeat transmembrane neuronal 3
chr6_+_4755327	19.645	ENSMUST00000176551.1	Peg10	paternally expressed 10
chr3_+_102010138	12.721	ENSMUST00000066187.4	Nhlh2	nescient helix loop helix 2
chr12_+_72441933	11.898	ENSMUST00000161284.1	Lrrc9	leucine rich repeat containing 9
chr1_-_158958367	10.423	ENSMUST00000159861.2	Pappa2	pappalysin 2
chr12_+_72441852	8.742	ENSMUST00000162159.1	Lrrc9	leucine rich repeat containing 9
chrX_-_43274786	7.931	ENSMUST00000016294.7	Tenm1	teneurin transmembrane protein 1
chr4_+_62965560	7.345	ENSMUST00000030043.6 ENSMUST00000107415.1 ENSMUST00000064814.5	Zfp618	zinc finger protein 618
chr3_+_125404072	6.754	ENSMUST00000173932.1	Ndst4	N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr3_+_125404292	6.241	ENSMUST00000144344.1	Ndst4	N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr7_+_35802593	6.138	ENSMUST00000052454.2	E130304I02Rik	RIKEN cDNA E130304I02 gene
chrX_+_134404780	5.874	ENSMUST00000113224.2 ENSMUST00000113226.1	Drp2	dystrophin related protein 2
chr8_-_58911627	5.278	ENSMUST00000077447.4	Galntl6	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 6
chrX_+_134404543	5.142	ENSMUST00000113228.1 ENSMUST00000153424.1	Drp2	dystrophin related protein 2
chr1_+_165302625	4.990	ENSMUST00000111450.1	Gpr161	G protein-coupled receptor 161
chr8_+_58911755	4.847	ENSMUST00000062978.6	BC030500	cDNA sequence BC030500
chr18_-_72351009	4.738	ENSMUST00000073379.5	Dcc	deleted in colorectal carcinoma
chr18_-_72351029	4.725	ENSMUST00000114943.3	Dcc	deleted in colorectal carcinoma
chr19_-_57197377	4.221	ENSMUST00000111546.1	Ablim1	actin-binding LIM protein 1
chr9_-_50739365	4.184	ENSMUST00000117093.1 ENSMUST00000121634.1	Dixdc1	DIX domain containing 1
chr19_-_57197435	4.168	ENSMUST00000111550.1	Ablim1	actin-binding LIM protein 1
chr4_-_97584605	4.118	ENSMUST00000107067.1	E130114P18Rik	RIKEN cDNA E130114P18 gene
chr4_-_97584612	4.088	ENSMUST00000107068.2	E130114P18Rik	RIKEN cDNA E130114P18 gene
chr19_-_37178011	4.078	ENSMUST00000133988.1	Cpeb3	cytoplasmic polyadenylation element binding protein 3
chr19_-_57197496	3.750	ENSMUST00000111544.1	Ablim1	actin-binding LIM protein 1
chr2_-_72986716	3.745	ENSMUST00000112062.1	Gm11084	predicted gene 11084
chr13_+_93304940	3.727	ENSMUST00000109497.1 ENSMUST00000109498.1 ENSMUST00000060490.4 ENSMUST00000109492.1 ENSMUST00000109496.1 ENSMUST00000109495.1	Homer1	homer homolog 1 (Drosophila)
chr12_+_55598917	3.665	ENSMUST00000051857.3	Insm2	insulinoma-associated 2
chr13_+_93304799	3.400	ENSMUST00000080127.5	Homer1	homer homolog 1 (Drosophila)
chr3_+_8509477	3.292	ENSMUST00000029002.7	Stmn2	stathmin-like 2
chr2_-_168767136	3.276	ENSMUST00000029061.5 ENSMUST00000103074.1	Sall4	sal-like 4 (Drosophila)
chr15_-_103215285	3.248	ENSMUST00000122182.1 ENSMUST00000108813.3 ENSMUST00000127191.1	Cbx5	chromobox 5
chr11_+_120232921	3.205	ENSMUST00000122148.1 ENSMUST00000044985.7	Bahcc1	BAH domain and coiled-coil containing 1
chr7_+_75848338	2.911	ENSMUST00000092073.5 ENSMUST00000171155.2	Klhl25	kelch-like 25
chr1_-_89933290	2.838	ENSMUST00000036954.7	Gbx2	gastrulation brain homeobox 2
chr1_+_191717834	2.767	ENSMUST00000110855.1 ENSMUST00000133076.1	Lpgat1	lysophosphatidylglycerol acyltransferase 1
chr7_-_127448993	2.693	ENSMUST00000106299.1	Zfp689	zinc finger protein 689
chr14_-_55092277	2.618	ENSMUST00000036328.8	Zfhx2	zinc finger homeobox 2
chr3_+_94372794	2.616	ENSMUST00000029795.3	Rorc	RAR-related orphan receptor gamma
chr7_-_127449109	2.608	ENSMUST00000053392.4	Zfp689	zinc finger protein 689
chr1_-_54194048	2.601	ENSMUST00000120904.1	Hecw2	HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
chr12_-_46818749	2.438	ENSMUST00000021438.6	Nova1	neuro-oncological ventral antigen 1
chr15_+_92161343	2.282	ENSMUST00000068378.5	Cntn1	contactin 1
chr3_-_33082004	2.208	ENSMUST00000108225.3	Pex5l	peroxisomal biogenesis factor 5-like
chr19_-_57197556	2.066	ENSMUST00000099294.2	Ablim1	actin-binding LIM protein 1
chr10_-_112928974	2.022	ENSMUST00000099276.2	Atxn7l3b	ataxin 7-like 3B
chr8_-_8660773	1.924	ENSMUST00000001319.7	Efnb2	ephrin B2
chr8_+_20136455	1.691	ENSMUST00000179299.1 ENSMUST00000096485.4	Gm21811	predicted gene, 21811
chr4_+_109343029	1.621	ENSMUST00000030281.5	Eps15	epidermal growth factor receptor pathway substrate 15
chr5_+_92683625	1.594	ENSMUST00000168878.1	Shroom3	shroom family member 3
chr2_-_25224653	1.521	ENSMUST00000043584.4	Tubb4b	tubulin, beta 4B class IVB
chr8_-_79399513	1.433	ENSMUST00000066091.7 ENSMUST00000109885.1 ENSMUST00000066081.3	Smad1	SMAD family member 1
chr2_-_168767029	1.400	ENSMUST00000075044.3	Sall4	sal-like 4 (Drosophila)
chr3_-_79842662	1.309	ENSMUST00000029568.1	Tmem144	transmembrane protein 144
chr9_+_59589288	1.305	ENSMUST00000121266.1 ENSMUST00000118164.1	Celf6	CUGBP, Elav-like family member 6
chr7_+_25152456	1.293	ENSMUST00000098678.1	D930028M14Rik	RIKEN cDNA D930028M14 gene
chrX_-_51205990	1.234	ENSMUST00000114876.2	Mbnl3	muscleblind-like 3 (Drosophila)
chr8_+_127064107	1.210	ENSMUST00000162536.1 ENSMUST00000026921.6 ENSMUST00000162665.1 ENSMUST00000160766.1 ENSMUST00000162602.1 ENSMUST00000162531.1 ENSMUST00000160581.1 ENSMUST00000161355.1 ENSMUST00000159537.1	Pard3	par-3 (partitioning defective 3) homolog (C. elegans)
chrX_+_56609751	1.065	ENSMUST00000144068.1	Slc9a6	solute carrier family 9 (sodium/hydrogen exchanger), member 6
chr9_+_54980880	1.049	ENSMUST00000093844.3	Chrna5	cholinergic receptor, nicotinic, alpha polypeptide 5
chr2_+_163602294	1.045	ENSMUST00000171696.1 ENSMUST00000109408.3	Ttpal	tocopherol (alpha) transfer protein-like
chr5_+_63649335	0.990	ENSMUST00000159584.1	3110047P20Rik	RIKEN cDNA 3110047P20 gene
chr11_+_29373618	0.946	ENSMUST00000040182.6 ENSMUST00000109477.1	Ccdc88a	coiled coil domain containing 88A
chr13_-_54688246	0.938	ENSMUST00000122935.1 ENSMUST00000128257.1	Rnf44	ring finger protein 44
chr2_-_7081207	0.825	ENSMUST00000114923.2 ENSMUST00000182706.1	Celf2	CUGBP, Elav-like family member 2
chr16_+_32431225	0.818	ENSMUST00000115140.1	Pcyt1a	phosphate cytidylyltransferase 1, choline, alpha isoform
chr1_-_54438940	0.772	ENSMUST00000041638.6	Gtf3c3	general transcription factor IIIC, polypeptide 3
chr14_+_69029289	0.768	ENSMUST00000014957.8	Stc1	stanniocalcin 1
chr4_-_110292719	0.722	ENSMUST00000106601.1	Elavl4	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr8_+_127064022	0.676	ENSMUST00000160272.1 ENSMUST00000079777.5 ENSMUST00000162907.1	Pard3	par-3 (partitioning defective 3) homolog (C. elegans)
chr9_-_114844090	0.650	ENSMUST00000047013.3	Cmtm8	CKLF-like MARVEL transmembrane domain containing 8
chr6_-_23132981	0.605	ENSMUST00000031707.7	Aass	aminoadipate-semialdehyde synthase
chr2_+_163602331	0.588	ENSMUST00000152135.1	Ttpal	tocopherol (alpha) transfer protein-like
chr16_+_32430895	0.572	ENSMUST00000115137.1 ENSMUST00000079791.4	Pcyt1a	phosphate cytidylyltransferase 1, choline, alpha isoform
chr2_-_7081256	0.563	ENSMUST00000183209.1	Celf2	CUGBP, Elav-like family member 2
chr2_-_32451396	0.555	ENSMUST00000028160.8 ENSMUST00000113310.2	Slc25a25	solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25
chr11_+_97315716	0.526	ENSMUST00000019026.3 ENSMUST00000132168.1	Mrpl45	mitochondrial ribosomal protein L45
chr11_-_120624973	0.503	ENSMUST00000106183.2 ENSMUST00000080202.5	Sirt7	sirtuin 7
chr2_+_130277157	0.475	ENSMUST00000028890.8 ENSMUST00000159373.1	Nop56	NOP56 ribonucleoprotein
chr7_+_125444635	0.435	ENSMUST00000033010.2 ENSMUST00000135129.1	Kdm8	lysine (K)-specific demethylase 8
chr17_-_24479034	0.395	ENSMUST00000179163.1 ENSMUST00000070888.6	Mlst8	MTOR associated protein, LST8 homolog (S. cerevisiae)
chr7_+_67647405	0.385	ENSMUST00000032774.8 ENSMUST00000107471.1	Ttc23	tetratricopeptide repeat domain 23
chr7_+_45627482	0.380	ENSMUST00000057927.7	Rasip1	Ras interacting protein 1
chr18_+_35965036	0.337	ENSMUST00000176873.1 ENSMUST00000177432.1	Psd2	pleckstrin and Sec7 domain containing 2
chr9_-_29963112	0.332	ENSMUST00000075069.4	Ntm	neurotrimin
chr6_-_56704673	0.312	ENSMUST00000170382.2	Lsm5	LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr7_-_116084635	0.312	ENSMUST00000111755.3	Gm4353	predicted gene 4353
chr12_-_80260091	0.287	ENSMUST00000167327.1	Actn1	actinin, alpha 1
chr17_+_55986494	0.217	ENSMUST00000011733.8	Fsd1	fibronectin type 3 and SPRY domain-containing protein
chrX_+_101377267	0.211	ENSMUST00000052130.7	Gjb1	gap junction protein, beta 1
chr18_+_35965088	0.174	ENSMUST00000175734.1	Psd2	pleckstrin and Sec7 domain containing 2
chr17_-_46440099	0.129	ENSMUST00000166852.1	Gm5093	predicted gene 5093
chr7_+_67655414	0.051	ENSMUST00000107470.1	Ttc23	tetratricopeptide repeat domain 23
chr11_+_4902212	0.026	ENSMUST00000142543.1	Thoc5	THO complex 5
chr8_-_91801547	0.000	ENSMUST00000093312.4	Irx3	Iroquois related homeobox 3 (Drosophila)

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
7.5	45.2	GO:0021797	forebrain anterior/posterior pattern specification(GO:0021797)
6.9	20.7	GO:0045110	intermediate filament bundle assembly(GO:0045110)
2.7	40.4	GO:1902004	positive regulation of beta-amyloid formation(GO:1902004)
1.6	9.5	GO:0021965	spinal cord ventral commissure morphogenesis(GO:0021965)
1.4	4.1	GO:0002182	cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
1.1	3.3	GO:0031117	positive regulation of microtubule depolymerization(GO:0031117)
0.5	1.6	GO:0019065	receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.5	7.1	GO:2001256	regulation of store-operated calcium entry(GO:2001256)
0.5	1.4	GO:0006657	CDP-choline pathway(GO:0006657)
0.5	5.0	GO:1901621	negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.4	12.7	GO:0007617	mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.4	2.8	GO:0021555	midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.3	2.6	GO:0072615	interleukin-17 secretion(GO:0072615)
0.3	4.2	GO:0021869	forebrain ventricular zone progenitor cell division(GO:0021869)
0.3	2.2	GO:0051461	protein import into peroxisome matrix, docking(GO:0016560) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.3	1.9	GO:0003383	apical constriction(GO:0003383)
0.3	19.6	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512)
0.3	4.7	GO:0001833	inner cell mass cell proliferation(GO:0001833)
0.2	1.9	GO:1903847	regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.2	1.4	GO:0002051	osteoblast fate commitment(GO:0002051)
0.2	3.2	GO:0031507	heterochromatin assembly(GO:0031507)
0.2	0.6	GO:0006553	lysine metabolic process(GO:0006553)
0.2	0.9	GO:1903566	positive regulation of protein localization to cilium(GO:1903566)
0.2	7.9	GO:0007218	neuropeptide signaling pathway(GO:0007218)
0.2	2.8	GO:0045723	positive regulation of fatty acid biosynthetic process(GO:0045723)
0.2	14.2	GO:0030032	lamellipodium assembly(GO:0030032)
0.1	1.1	GO:0031547	brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
0.1	1.0	GO:0035095	behavioral response to nicotine(GO:0035095)
0.1	0.6	GO:0031580	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1	0.5	GO:0045896	regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.1	1.3	GO:0034219	carbohydrate transmembrane transport(GO:0034219)
0.1	11.2	GO:0060349	bone morphogenesis(GO:0060349)
0.0	1.2	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.0	2.6	GO:0006446	regulation of translational initiation(GO:0006446)
0.0	2.6	GO:0030071	regulation of mitotic metaphase/anaphase transition(GO:0030071) regulation of metaphase/anaphase transition of cell cycle(GO:1902099)
0.0	1.3	GO:0071625	vocalization behavior(GO:0071625)
0.0	0.4	GO:0070544	histone H3-K36 demethylation(GO:0070544)
0.0	1.4	GO:0006376	mRNA splice site selection(GO:0006376)
0.0	0.6	GO:0014823	response to activity(GO:0014823)
0.0	1.6	GO:0002066	columnar/cuboidal epithelial cell development(GO:0002066)
0.0	0.8	GO:0006383	transcription from RNA polymerase III promoter(GO:0006383)
0.0	0.2	GO:0015868	purine ribonucleotide transport(GO:0015868)
0.0	0.5	GO:0032011	ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0	0.3	GO:0051639	actin filament network formation(GO:0051639)
0.0	2.3	GO:0021549	cerebellum development(GO:0021549)
0.0	0.5	GO:0000154	rRNA modification(GO:0000154)
0.0	3.4	GO:0050808	synapse organization(GO:0050808)
0.0	1.8	GO:0030534	adult behavior(GO:0030534)
0.0	0.4	GO:0032008	positive regulation of TOR signaling(GO:0032008)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
6.9	20.7	GO:0033596	TSC1-TSC2 complex(GO:0033596)
0.9	9.5	GO:0032584	growth cone membrane(GO:0032584)
0.6	2.2	GO:0017071	intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.3	3.2	GO:0005677	chromatin silencing complex(GO:0005677)
0.2	1.9	GO:0033269	internode region of axon(GO:0033269)
0.2	4.1	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
0.2	1.1	GO:0044308	axonal spine(GO:0044308)
0.2	3.2	GO:0010369	chromocenter(GO:0010369)
0.2	1.4	GO:0042587	glycogen granule(GO:0042587)
0.2	1.5	GO:0045298	tubulin complex(GO:0045298)
0.2	51.6	GO:0045211	postsynaptic membrane(GO:0045211)
0.1	1.6	GO:0030122	AP-2 adaptor complex(GO:0030122)
0.1	14.5	GO:0001725	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1	0.8	GO:0000127	transcription factor TFIIIC complex(GO:0000127)
0.1	0.5	GO:0031428	box C/D snoRNP complex(GO:0031428)
0.1	0.3	GO:1990726	Lsm1-7-Pat1 complex(GO:1990726)
0.0	0.7	GO:0042788	polysomal ribosome(GO:0042788)
0.0	2.9	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	4.7	GO:0000792	heterochromatin(GO:0000792)
0.0	0.4	GO:0031931	TORC1 complex(GO:0031931)
0.0	1.4	GO:0005637	nuclear inner membrane(GO:0005637)
0.0	0.5	GO:0097610	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0	2.6	GO:0072686	mitotic spindle(GO:0072686)
0.0	3.9	GO:0055037	recycling endosome(GO:0055037)
0.0	4.2	GO:0043679	axon terminus(GO:0043679)
0.0	4.2	GO:0030027	lamellipodium(GO:0030027)
0.0	0.2	GO:0005922	connexon complex(GO:0005922)
0.0	1.6	GO:0043296	apical junction complex(GO:0043296)
0.0	59.1	GO:0005829	cytosol(GO:0005829)
0.0	2.3	GO:0043209	myelin sheath(GO:0043209)
0.0	1.9	GO:0005925	focal adhesion(GO:0005925)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.9	13.0	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
1.6	9.5	GO:0005042	netrin receptor activity(GO:0005042)
0.8	20.7	GO:0043274	phospholipase binding(GO:0043274)
0.7	2.6	GO:0008142	oxysterol binding(GO:0008142)
0.6	7.1	GO:0031802	type 5 metabotropic glutamate receptor binding(GO:0031802)
0.4	2.2	GO:0005052	peroxisome matrix targeting signal-1 binding(GO:0005052)
0.4	40.4	GO:0004860	protein kinase inhibitor activity(GO:0004860)
0.3	4.1	GO:0035925	mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.3	1.4	GO:0004105	choline-phosphate cytidylyltransferase activity(GO:0004105)
0.2	12.7	GO:0001102	RNA polymerase II activating transcription factor binding(GO:0001102)
0.2	38.4	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.2	0.8	GO:0000995	transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.2	1.4	GO:0017151	DEAD/H-box RNA helicase binding(GO:0017151)
0.1	1.1	GO:0015386	potassium:proton antiporter activity(GO:0015386)
0.1	0.5	GO:0034739	histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.1	10.4	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.1	4.0	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1	1.0	GO:0022848	acetylcholine-gated cation channel activity(GO:0022848)
0.1	0.6	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.1	0.6	GO:0015217	ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0	0.9	GO:0043422	protein kinase B binding(GO:0043422)
0.0	3.2	GO:0035064	methylated histone binding(GO:0035064)
0.0	1.9	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0	3.3	GO:0048306	calcium-dependent protein binding(GO:0048306)
0.0	1.9	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	1.6	GO:0031593	polyubiquitin binding(GO:0031593)
0.0	15.2	GO:0003779	actin binding(GO:0003779)
0.0	0.5	GO:1990226	histone methyltransferase binding(GO:1990226)
0.0	0.4	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	2.2	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0	0.7	GO:0017091	AU-rich element binding(GO:0017091)
0.0	1.4	GO:0036002	pre-mRNA binding(GO:0036002)
0.0	21.9	GO:0008270	zinc ion binding(GO:0008270)
0.0	1.3	GO:0015144	carbohydrate transmembrane transporter activity(GO:0015144) carbohydrate transporter activity(GO:1901476)
0.0	1.5	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.0	0.6	GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0	3.7	GO:0003714	transcription corepressor activity(GO:0003714)
0.0	0.2	GO:0005243	gap junction channel activity(GO:0005243)
0.0	0.5	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	3.5	GO:0061659	ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0	2.7	GO:0004930	G-protein coupled receptor activity(GO:0004930)
0.0	0.4	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	0.8	GO:0005179	hormone activity(GO:0005179)
0.0	2.8	GO:0016746	transferase activity, transferring acyl groups(GO:0016746)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	9.5	PID_NETRIN_PATHWAY	Netrin-mediated signaling events
0.2	19.6	PID_MYC_ACTIV_PATHWAY	Validated targets of C-MYC transcriptional activation
0.1	1.4	PID_ALK2_PATHWAY	ALK2 signaling events
0.1	3.2	PID_AURORA_B_PATHWAY	Aurora B signaling
0.1	1.9	PID_EPHRINB_REV_PATHWAY	Ephrin B reverse signaling
0.0	4.2	WNT_SIGNALING	Genes related to Wnt-mediated signal transduction
0.0	3.9	PID_NOTCH_PATHWAY	Notch signaling pathway
0.0	4.1	PID_BETA_CATENIN_NUC_PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.0	1.9	SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES	Genes related to the insulin receptor pathway
0.0	0.5	PID_HDAC_CLASSIII_PATHWAY	Signaling events mediated by HDAC Class III
0.0	0.4	PID_PI3KCI_AKT_PATHWAY	Class I PI3K signaling events mediated by Akt
0.0	0.3	PID_SYNDECAN_4_PATHWAY	Syndecan-4-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.9	23.7	REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING	Genes involved in DCC mediated attractive signaling
0.8	20.7	REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
0.7	10.4	REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.3	13.0	REACTOME_HS_GAG_BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.3	2.8	REACTOME_ACYL_CHAIN_REMODELLING_OF_PG	Genes involved in Acyl chain remodelling of PG
0.1	1.0	REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1	5.3	REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS	Genes involved in O-linked glycosylation of mucins
0.1	1.5	REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.1	1.9	REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1	2.3	REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0	1.4	REACTOME_SIGNALING_BY_BMP	Genes involved in Signaling by BMP
0.0	2.6	REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	0.8	REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_2_PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0	3.2	REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	0.9	REACTOME_EGFR_DOWNREGULATION	Genes involved in EGFR downregulation
0.0	0.4	REACTOME_MTORC1_MEDIATED_SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	0.3	REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.2	REACTOME_GAP_JUNCTION_ASSEMBLY	Genes involved in Gap junction assembly
0.0	0.3	REACTOME_NEPHRIN_INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.5	REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis

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