Motif ID: Pax1_Pax9
Z-value: 0.399
Transcription factors associated with Pax1_Pax9:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Pax1 | ENSMUSG00000037034.9 | Pax1 |
Pax9 | ENSMUSG00000001497.12 | Pax9 |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.2 | 3.6 | GO:1904170 | regulation of bleb assembly(GO:1904170) |
0.4 | 3.9 | GO:0033504 | floor plate development(GO:0033504) |
0.3 | 1.3 | GO:1901187 | regulation of ephrin receptor signaling pathway(GO:1901187) |
0.1 | 1.3 | GO:0042118 | endothelial cell activation(GO:0042118) |
0.1 | 0.5 | GO:1901731 | positive regulation of platelet aggregation(GO:1901731) |
0.1 | 0.2 | GO:2000793 | cell proliferation involved in heart valve development(GO:2000793) |
0.1 | 0.4 | GO:0006564 | L-serine biosynthetic process(GO:0006564) |
0.1 | 0.5 | GO:0035902 | response to immobilization stress(GO:0035902) |
0.1 | 1.4 | GO:0043923 | positive regulation by host of viral transcription(GO:0043923) |
0.1 | 1.8 | GO:0008340 | determination of adult lifespan(GO:0008340) |
0.1 | 0.4 | GO:0006172 | ADP biosynthetic process(GO:0006172) |
0.1 | 0.4 | GO:0048793 | pronephros development(GO:0048793) |
0.0 | 0.6 | GO:0070986 | left/right axis specification(GO:0070986) |
0.0 | 0.8 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) ubiquinone biosynthetic process(GO:0006744) |
0.0 | 0.2 | GO:1904936 | cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936) |
0.0 | 0.2 | GO:0009098 | branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099) |
0.0 | 0.5 | GO:0016226 | iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163) |
0.0 | 2.2 | GO:0043488 | regulation of mRNA stability(GO:0043488) |
0.0 | 1.2 | GO:1904893 | negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.7 | 3.6 | GO:0005826 | actomyosin contractile ring(GO:0005826) |
0.2 | 2.7 | GO:0042788 | polysomal ribosome(GO:0042788) |
0.1 | 0.5 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
0.0 | 3.9 | GO:0005814 | centriole(GO:0005814) |
0.0 | 1.4 | GO:0005669 | transcription factor TFIID complex(GO:0005669) |
0.0 | 0.6 | GO:0097225 | sperm midpiece(GO:0097225) |
0.0 | 1.2 | GO:0032809 | neuronal cell body membrane(GO:0032809) |
0.0 | 1.8 | GO:0090575 | RNA polymerase II transcription factor complex(GO:0090575) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 1.3 | GO:0001011 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) |
0.3 | 1.8 | GO:0015616 | DNA translocase activity(GO:0015616) |
0.1 | 0.4 | GO:0004647 | phosphoserine phosphatase activity(GO:0004647) |
0.1 | 0.4 | GO:0046899 | nucleoside triphosphate adenylate kinase activity(GO:0046899) |
0.1 | 1.4 | GO:0042809 | vitamin D receptor binding(GO:0042809) |
0.1 | 2.2 | GO:0017091 | AU-rich element binding(GO:0017091) |
0.1 | 0.2 | GO:0052740 | phosphatidylserine 1-acylhydrolase activity(GO:0052739) 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740) |
0.1 | 1.2 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
0.0 | 0.5 | GO:0015250 | water channel activity(GO:0015250) |
0.0 | 0.2 | GO:0052654 | branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656) |
0.0 | 1.3 | GO:0046875 | ephrin receptor binding(GO:0046875) |
0.0 | 0.8 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
0.0 | 0.5 | GO:0051537 | 2 iron, 2 sulfur cluster binding(GO:0051537) |
0.0 | 0.5 | GO:0000217 | DNA secondary structure binding(GO:0000217) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 3.9 | PID_HEDGEHOG_2PATHWAY | Signaling events mediated by the Hedgehog family |
0.0 | 0.5 | PID_ERB_GENOMIC_PATHWAY | Validated nuclear estrogen receptor beta network |
0.0 | 1.8 | PID_E2F_PATHWAY | E2F transcription factor network |
0.0 | 1.3 | PID_AR_PATHWAY | Coregulation of Androgen receptor activity |
0.0 | 0.6 | PID_HEDGEHOG_GLI_PATHWAY | Hedgehog signaling events mediated by Gli proteins |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 1.1 | REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS | Genes involved in Amine compound SLC transporters |
0.0 | 1.3 | REACTOME_MYOGENESIS | Genes involved in Myogenesis |
0.0 | 1.4 | REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING | Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening |
0.0 | 0.4 | REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION | Genes involved in Amino acid synthesis and interconversion (transamination) |