Motif ID: Pax1_Pax9

Z-value: 0.399

Transcription factors associated with Pax1_Pax9:

Gene SymbolEntrez IDGene Name
Pax1 ENSMUSG00000037034.9 Pax1
Pax9 ENSMUSG00000001497.12 Pax9






Network of associatons between targets according to the STRING database.



First level regulatory network of Pax1_Pax9

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_90969768 3.893 ENSMUST00000181184.1
4930544I03Rik
RIKEN cDNA 4930544I03 gene
chr9_-_22389113 3.586 ENSMUST00000040912.7
Anln
anillin, actin binding protein
chr4_-_110286581 2.188 ENSMUST00000138972.1
Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr4_+_115000156 2.174 ENSMUST00000030490.6
Stil
Scl/Tal1 interrupting locus
chr4_+_11558914 1.838 ENSMUST00000178703.1
ENSMUST00000095145.5
ENSMUST00000108306.2
ENSMUST00000070755.6
Rad54b



RAD54 homolog B (S. cerevisiae)



chr9_+_96196246 1.812 ENSMUST00000165120.2
ENSMUST00000034982.9
Tfdp2

transcription factor Dp 2

chr4_+_115000174 1.743 ENSMUST00000129957.1
Stil
Scl/Tal1 interrupting locus
chr2_+_84734050 1.675 ENSMUST00000090729.2
Ypel4
yippee-like 4 (Drosophila)
chr17_-_27909206 1.366 ENSMUST00000114848.1
Taf11
TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr18_+_69344503 1.335 ENSMUST00000114985.3
Tcf4
transcription factor 4
chr17_+_27909337 1.261 ENSMUST00000114842.1
ENSMUST00000025058.7
ENSMUST00000088027.5
Anks1


ankyrin repeat and SAM domain containing 1


chr19_-_7105729 1.235 ENSMUST00000113383.2
Flrt1
fibronectin leucine rich transmembrane protein 1
chr9_+_21337828 1.120 ENSMUST00000034697.7
Slc44a2
solute carrier family 44, member 2
chr13_-_62607499 0.971 ENSMUST00000091563.4
6720489N17Rik
RIKEN cDNA 6720489N17 gene
chr13_-_62520451 0.939 ENSMUST00000082203.6
ENSMUST00000101547.4
Zfp934

zinc finger protein 934

chr8_+_94838321 0.755 ENSMUST00000034234.8
ENSMUST00000159871.1
Coq9

coenzyme Q9 homolog (yeast)

chr5_-_31291026 0.631 ENSMUST00000041565.7
Ift172
intraflagellar transport 172
chr13_-_62777089 0.555 ENSMUST00000167516.2
Gm5141
predicted gene 5141
chr8_-_94838255 0.549 ENSMUST00000161762.1
ENSMUST00000162538.1
Ciapin1

cytokine induced apoptosis inhibitor 1

chrX_+_86191764 0.516 ENSMUST00000026036.4
Nr0b1
nuclear receptor subfamily 0, group B, member 1
chr4_-_143299498 0.502 ENSMUST00000030317.7
Pdpn
podoplanin
chr5_-_93206489 0.427 ENSMUST00000058550.8
Ccni
cyclin I
chr6_-_88518760 0.418 ENSMUST00000032168.5
Sec61a1
Sec61 alpha 1 subunit (S. cerevisiae)
chr5_-_129787175 0.399 ENSMUST00000031399.6
Psph
phosphoserine phosphatase
chr19_-_29047847 0.380 ENSMUST00000025696.4
Ak3
adenylate kinase 3
chr5_-_93206428 0.351 ENSMUST00000144514.1
Ccni
cyclin I
chr7_-_24299310 0.300 ENSMUST00000145131.1
Zfp61
zinc finger protein 61
chr2_-_33468493 0.292 ENSMUST00000113156.1
ENSMUST00000028125.5
ENSMUST00000126442.1
Zbtb43


zinc finger and BTB domain containing 43


chr2_-_36105271 0.239 ENSMUST00000112960.1
ENSMUST00000112967.5
ENSMUST00000112963.1
Lhx6


LIM homeobox protein 6


chr12_+_33957645 0.199 ENSMUST00000049089.5
Twist1
twist basic helix-loop-helix transcription factor 1
chr6_-_145048809 0.184 ENSMUST00000032402.5
Bcat1
branched chain aminotransferase 1, cytosolic
chr18_-_10706688 0.170 ENSMUST00000002549.7
ENSMUST00000117726.1
ENSMUST00000117828.1
Abhd3


abhydrolase domain containing 3


chr11_+_83753689 0.156 ENSMUST00000001002.7
Heatr6
HEAT repeat containing 6
chr7_+_48789003 0.081 ENSMUST00000118927.1
ENSMUST00000125280.1
Zdhhc13

zinc finger, DHHC domain containing 13

chr4_-_143299463 0.037 ENSMUST00000119654.1
Pdpn
podoplanin
chr9_-_97111117 0.004 ENSMUST00000085206.4
Slc25a36
solute carrier family 25, member 36

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.6 GO:1904170 regulation of bleb assembly(GO:1904170)
0.4 3.9 GO:0033504 floor plate development(GO:0033504)
0.3 1.3 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.1 1.3 GO:0042118 endothelial cell activation(GO:0042118)
0.1 0.5 GO:1901731 positive regulation of platelet aggregation(GO:1901731)
0.1 0.2 GO:2000793 cell proliferation involved in heart valve development(GO:2000793)
0.1 0.4 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.1 0.5 GO:0035902 response to immobilization stress(GO:0035902)
0.1 1.4 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.1 1.8 GO:0008340 determination of adult lifespan(GO:0008340)
0.1 0.4 GO:0006172 ADP biosynthetic process(GO:0006172)
0.1 0.4 GO:0048793 pronephros development(GO:0048793)
0.0 0.6 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.8 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120) ubiquinone biosynthetic process(GO:0006744)
0.0 0.2 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.2 GO:0009098 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.0 0.5 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 2.2 GO:0043488 regulation of mRNA stability(GO:0043488)
0.0 1.2 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.6 GO:0005826 actomyosin contractile ring(GO:0005826)
0.2 2.7 GO:0042788 polysomal ribosome(GO:0042788)
0.1 0.5 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 3.9 GO:0005814 centriole(GO:0005814)
0.0 1.4 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.6 GO:0097225 sperm midpiece(GO:0097225)
0.0 1.2 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 1.8 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.3 1.8 GO:0015616 DNA translocase activity(GO:0015616)
0.1 0.4 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.1 0.4 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.1 1.4 GO:0042809 vitamin D receptor binding(GO:0042809)
0.1 2.2 GO:0017091 AU-rich element binding(GO:0017091)
0.1 0.2 GO:0052740 phosphatidylserine 1-acylhydrolase activity(GO:0052739) 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.1 1.2 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.5 GO:0015250 water channel activity(GO:0015250)
0.0 0.2 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 1.3 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.8 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.5 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.5 GO:0000217 DNA secondary structure binding(GO:0000217)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.9 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.5 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.8 PID_E2F_PATHWAY E2F transcription factor network
0.0 1.3 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.0 0.6 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 1.3 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.0 1.4 REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.4 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)