Motif ID: Pax8
Z-value: 0.494
Transcription factors associated with Pax8:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Pax8 | ENSMUSG00000026976.9 | Pax8 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Pax8 | mm10_v2_chr2_-_24475564_24475580 | -0.07 | 5.4e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.8 | 4.8 | GO:0051987 | positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987) |
0.5 | 2.5 | GO:0072530 | purine-containing compound transmembrane transport(GO:0072530) |
0.4 | 4.8 | GO:2001269 | positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269) |
0.3 | 3.8 | GO:0014883 | transition between fast and slow fiber(GO:0014883) |
0.3 | 2.1 | GO:2000252 | negative regulation of feeding behavior(GO:2000252) |
0.3 | 1.5 | GO:0034773 | histone H4-K20 trimethylation(GO:0034773) establishment of Sertoli cell barrier(GO:0097368) |
0.1 | 0.3 | GO:0014809 | regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809) |
0.1 | 0.4 | GO:0030043 | actin filament fragmentation(GO:0030043) |
0.1 | 1.2 | GO:0031468 | nuclear envelope reassembly(GO:0031468) |
0.1 | 0.9 | GO:0019368 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
0.1 | 0.4 | GO:0032329 | serine transport(GO:0032329) |
0.1 | 1.5 | GO:0032288 | myelin assembly(GO:0032288) |
0.0 | 1.0 | GO:0000132 | establishment of mitotic spindle orientation(GO:0000132) |
0.0 | 0.1 | GO:0031053 | primary miRNA processing(GO:0031053) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.0 | 3.8 | GO:0071148 | TEAD-1-YAP complex(GO:0071148) |
0.4 | 4.8 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) mitotic spindle midzone(GO:1990023) |
0.1 | 1.5 | GO:0032593 | insulin-responsive compartment(GO:0032593) |
0.0 | 4.8 | GO:0032993 | protein-DNA complex(GO:0032993) |
0.0 | 0.3 | GO:0016010 | dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665) |
0.0 | 1.5 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.0 | 4.8 | GO:0043515 | kinetochore binding(GO:0043515) |
0.7 | 2.1 | GO:0004980 | melanocortin receptor activity(GO:0004977) melanocyte-stimulating hormone receptor activity(GO:0004980) |
0.3 | 2.5 | GO:0005338 | nucleotide-sugar transmembrane transporter activity(GO:0005338) |
0.2 | 3.8 | GO:0001134 | transcription factor activity, transcription factor recruiting(GO:0001134) |
0.2 | 1.5 | GO:0016308 | 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308) |
0.1 | 0.9 | GO:0009922 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
0.0 | 0.3 | GO:0002162 | dystroglycan binding(GO:0002162) |
0.0 | 4.8 | GO:0001047 | core promoter binding(GO:0001047) |
0.0 | 1.9 | GO:0008083 | growth factor activity(GO:0008083) |
0.0 | 1.2 | GO:0019888 | protein phosphatase regulator activity(GO:0019888) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 2.1 | PID_SYNDECAN_3_PATHWAY | Syndecan-3-mediated signaling events |
0.1 | 4.8 | PID_PLK1_PATHWAY | PLK1 signaling events |
0.0 | 0.4 | ST_TUMOR_NECROSIS_FACTOR_PATHWAY | Tumor Necrosis Factor Pathway. |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 3.8 | REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
0.1 | 1.5 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE | Genes involved in Synthesis of PIPs at the early endosome membrane |
0.0 | 0.9 | REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
0.0 | 2.1 | REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS | Genes involved in Peptide ligand-binding receptors |
0.0 | 0.3 | REACTOME_STRIATED_MUSCLE_CONTRACTION | Genes involved in Striated Muscle Contraction |