---

Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr18_+_20665250	18.515	ENSMUST00000075312.3	Ttr	transthyretin
chr13_-_84064772	8.989	ENSMUST00000182477.1	Gm17750	predicted gene, 17750
chr14_+_99298652	4.925	ENSMUST00000005279.6	Klf5	Kruppel-like factor 5
chr10_+_97565436	4.642	ENSMUST00000038160.4	Lum	lumican
chr4_-_136898803	4.244	ENSMUST00000046285.5	C1qa	complement component 1, q subcomponent, alpha polypeptide
chr9_-_79718631	3.626	ENSMUST00000180083.1	Col12a1	collagen, type XII, alpha 1
chr9_-_79718518	3.320	ENSMUST00000071750.6	Col12a1	collagen, type XII, alpha 1
chr11_+_111066154	3.125	ENSMUST00000042970.2	Kcnj2	potassium inwardly-rectifying channel, subfamily J, member 2
chr9_-_79718720	3.092	ENSMUST00000121227.1	Col12a1	collagen, type XII, alpha 1
chr2_-_162661075	3.030	ENSMUST00000109442.1 ENSMUST00000109445.2 ENSMUST00000109443.1 ENSMUST00000109441.1	Ptprt	protein tyrosine phosphatase, receptor type, T
chr5_-_104114088	3.017	ENSMUST00000031249.3	Sparcl1	SPARC-like 1
chr2_+_65620829	2.936	ENSMUST00000028377.7	Scn2a1	sodium channel, voltage-gated, type II, alpha 1
chr5_+_24364804	2.813	ENSMUST00000030834.4 ENSMUST00000115090.1	Nos3	nitric oxide synthase 3, endothelial cell
chr6_+_17491216	2.652	ENSMUST00000080469.5	Met	met proto-oncogene
chr3_-_152193803	2.392	ENSMUST00000050073.6	Dnajb4	DnaJ (Hsp40) homolog, subfamily B, member 4
chr13_+_29016267	2.325	ENSMUST00000140415.1	A330102I10Rik	RIKEN cDNA A330102I10 gene
chr14_+_70555900	2.324	ENSMUST00000163060.1	Hr	hairless
chr13_+_91461050	2.227	ENSMUST00000004094.8 ENSMUST00000042122.8	Ssbp2	single-stranded DNA binding protein 2
chr16_+_43363855	2.149	ENSMUST00000156367.1	Zbtb20	zinc finger and BTB domain containing 20
chr7_-_127824469	2.147	ENSMUST00000106267.3	Stx1b	syntaxin 1B
chr17_-_68004075	2.136	ENSMUST00000024840.5	Arhgap28	Rho GTPase activating protein 28
chr9_-_49798729	2.064	ENSMUST00000166811.2	Ncam1	neural cell adhesion molecule 1
chr9_-_49798905	1.973	ENSMUST00000114476.2	Ncam1	neural cell adhesion molecule 1
chr10_+_100015817	1.963	ENSMUST00000130190.1 ENSMUST00000020129.7	Kitl	kit ligand
chr2_-_122611238	1.947	ENSMUST00000028624.8	Gatm	glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr11_-_110168073	1.916	ENSMUST00000044850.3	Abca9	ATP-binding cassette, sub-family A (ABC1), member 9
chr14_+_123659971	1.809	ENSMUST00000049681.7	Itgbl1	integrin, beta-like 1
chr10_-_116473418	1.781	ENSMUST00000087965.4 ENSMUST00000164271.1	Kcnmb4	potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr5_+_125441546	1.705	ENSMUST00000049040.9	Bri3bp	Bri3 binding protein
chr3_-_97868242	1.639	ENSMUST00000107038.3	Pde4dip	phosphodiesterase 4D interacting protein (myomegalin)
chr11_-_83649349	1.547	ENSMUST00000001008.5	Ccl3	chemokine (C-C motif) ligand 3
chr14_-_124677089	1.490	ENSMUST00000095529.3	Fgf14	fibroblast growth factor 14
chr5_+_65131184	1.446	ENSMUST00000031089.5 ENSMUST00000101191.3	Klhl5	kelch-like 5
chr7_-_78577771	1.401	ENSMUST00000039438.7	Ntrk3	neurotrophic tyrosine kinase, receptor, type 3
chr16_-_5222257	1.176	ENSMUST00000050160.4	AU021092	expressed sequence AU021092
chr15_-_12592556	1.160	ENSMUST00000075317.5	Pdzd2	PDZ domain containing 2
chr4_-_119422355	1.138	ENSMUST00000106316.1 ENSMUST00000030385.6	Ppcs	phosphopantothenoylcysteine synthetase
chr2_-_154613425	1.082	ENSMUST00000181369.1	4930519P11Rik	RIKEN cDNA 4930519P11 gene
chr13_+_75967704	1.068	ENSMUST00000022081.1	Spata9	spermatogenesis associated 9
chr4_+_136284708	1.022	ENSMUST00000130223.1	Zfp46	zinc finger protein 46
chr19_+_55316313	0.982	ENSMUST00000095950.2	Vti1a	vesicle transport through interaction with t-SNAREs 1A
chr4_+_136284658	0.973	ENSMUST00000144217.1	Zfp46	zinc finger protein 46
chr18_+_23415400	0.941	ENSMUST00000115832.2 ENSMUST00000047954.7	Dtna	dystrobrevin alpha
chr7_-_142576492	0.939	ENSMUST00000140716.1	H19	H19 fetal liver mRNA
chr16_+_90831113	0.934	ENSMUST00000037539.7 ENSMUST00000099543.3	Eva1c	eva-1 homolog C (C. elegans)
chr17_-_46031813	0.872	ENSMUST00000024747.7	Vegfa	vascular endothelial growth factor A
chr12_-_86988676	0.856	ENSMUST00000095521.2	Zdhhc22	zinc finger, DHHC-type containing 22
chr4_-_53159885	0.779	ENSMUST00000030010.3	Abca1	ATP-binding cassette, sub-family A (ABC1), member 1
chr11_+_105126425	0.753	ENSMUST00000021030.7	Mettl2	methyltransferase like 2
chr8_-_70234401	0.747	ENSMUST00000019679.5	Armc6	armadillo repeat containing 6
chr14_-_16575456	0.725	ENSMUST00000063750.6	Rarb	retinoic acid receptor, beta
chr18_+_9707639	0.698	ENSMUST00000040069.8	Colec12	collectin sub-family member 12
chr1_+_93235836	0.696	ENSMUST00000062202.7	Sned1	sushi, nidogen and EGF-like domains 1
chr10_-_109010955	0.692	ENSMUST00000105276.1 ENSMUST00000064054.7	Syt1	synaptotagmin I
chr15_+_81400132	0.675	ENSMUST00000163754.1 ENSMUST00000041609.4	Xpnpep3	X-prolyl aminopeptidase (aminopeptidase P) 3, putative
chr8_-_48555846	0.611	ENSMUST00000110345.1 ENSMUST00000110343.1	Tenm3	teneurin transmembrane protein 3
chr19_-_6084679	0.592	ENSMUST00000161548.1	Zfpl1	zinc finger like protein 1
chr7_+_144838590	0.559	ENSMUST00000105898.1	Fgf3	fibroblast growth factor 3
chr14_+_79451791	0.551	ENSMUST00000100359.1	Zbtbd6	kelch repeat and BTB (POZ) domain containing 6
chr12_+_103532435	0.550	ENSMUST00000021631.5	Ppp4r4	protein phosphatase 4, regulatory subunit 4
chr17_-_6961156	0.546	ENSMUST00000063683.6	Tagap1	T cell activation GTPase activating protein 1
chr15_+_82016420	0.520	ENSMUST00000168581.1 ENSMUST00000170630.1 ENSMUST00000164779.1	Xrcc6	X-ray repair complementing defective repair in Chinese hamster cells 6
chr3_+_121531603	0.498	ENSMUST00000180804.1	A530020G20Rik	RIKEN cDNA A530020G20 gene
chr2_-_63184253	0.496	ENSMUST00000075052.3 ENSMUST00000112454.1	Kcnh7	potassium voltage-gated channel, subfamily H (eag-related), member 7
chr5_+_30814571	0.493	ENSMUST00000031058.8	Mapre3	microtubule-associated protein, RP/EB family, member 3
chr17_-_25081138	0.493	ENSMUST00000024984.6	Tmem204	transmembrane protein 204
chr17_+_34644805	0.491	ENSMUST00000174796.1	Fkbpl	FK506 binding protein-like
chr8_+_123373778	0.479	ENSMUST00000057934.3 ENSMUST00000108840.2	Tcf25	transcription factor 25 (basic helix-loop-helix)
chr7_-_109616548	0.477	ENSMUST00000077909.1 ENSMUST00000084738.3	St5	suppression of tumorigenicity 5
chr5_+_30814722	0.465	ENSMUST00000114724.1	Mapre3	microtubule-associated protein, RP/EB family, member 3
chr2_+_91256144	0.456	ENSMUST00000154959.1 ENSMUST00000059566.4	Pacsin3	protein kinase C and casein kinase substrate in neurons 3
chr10_+_102158858	0.448	ENSMUST00000138522.1 ENSMUST00000163753.1 ENSMUST00000138016.1	Mgat4c	mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr2_+_163994960	0.437	ENSMUST00000018470.3	Ywhab	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
chr9_+_49102720	0.434	ENSMUST00000070390.5 ENSMUST00000167095.1	Tmprss5	transmembrane protease, serine 5 (spinesin)
chr19_-_6084873	0.434	ENSMUST00000160977.1 ENSMUST00000159859.1	Zfpl1	zinc finger like protein 1
chr1_-_71653162	0.423	ENSMUST00000055226.6	Fn1	fibronectin 1
chr3_+_106034661	0.411	ENSMUST00000170669.2	Gm4540	predicted gene 4540
chr7_+_30712209	0.409	ENSMUST00000005692.6 ENSMUST00000170371.1	Atp4a	ATPase, H+/K+ exchanging, gastric, alpha polypeptide
chr8_-_71043040	0.403	ENSMUST00000170101.1	Gm17576	predicted gene, 17576
chr7_+_49778334	0.402	ENSMUST00000140656.1 ENSMUST00000032715.6	Prmt3	protein arginine N-methyltransferase 3
chr19_+_55894508	0.378	ENSMUST00000142291.1	Tcf7l2	transcription factor 7 like 2, T cell specific, HMG box
chr2_-_77170592	0.374	ENSMUST00000164114.2 ENSMUST00000049544.7	Ccdc141	coiled-coil domain containing 141
chr15_-_89477400	0.355	ENSMUST00000165199.1	Arsa	arylsulfatase A
chr3_-_120886691	0.339	ENSMUST00000182099.1 ENSMUST00000183168.1 ENSMUST00000183276.1 ENSMUST00000182124.1	6530403H02Rik	RIKEN cDNA 6530403H02 gene
chr5_-_123140135	0.329	ENSMUST00000160099.1	AI480526	expressed sequence AI480526
chr12_-_4477138	0.327	ENSMUST00000085814.3	Ncoa1	nuclear receptor coactivator 1
chr10_+_14523062	0.312	ENSMUST00000096020.5	Gm10335	predicted gene 10335
chr2_-_65567505	0.299	ENSMUST00000100069.2	Scn3a	sodium channel, voltage-gated, type III, alpha
chr2_+_39008076	0.296	ENSMUST00000112862.1 ENSMUST00000090993.5	Arpc5l	actin related protein 2/3 complex, subunit 5-like
chr7_-_127725616	0.293	ENSMUST00000076091.2	Ctf2	cardiotrophin 2
chr2_-_65567465	0.292	ENSMUST00000066432.5	Scn3a	sodium channel, voltage-gated, type III, alpha
chr15_+_12117848	0.257	ENSMUST00000128475.1 ENSMUST00000134277.1	Zfr	zinc finger RNA binding protein
chr2_-_63184170	0.244	ENSMUST00000112452.1	Kcnh7	potassium voltage-gated channel, subfamily H (eag-related), member 7
chr19_+_8741669	0.239	ENSMUST00000176314.1 ENSMUST00000073430.7 ENSMUST00000175901.1	Stx5a	syntaxin 5A
chr14_-_69732510	0.228	ENSMUST00000036381.8	Chmp7	charged multivesicular body protein 7
chr4_-_143299463	0.227	ENSMUST00000119654.1	Pdpn	podoplanin
chr4_-_120815703	0.219	ENSMUST00000120779.1	Nfyc	nuclear transcription factor-Y gamma
chr11_+_87664274	0.213	ENSMUST00000092800.5	Rnf43	ring finger protein 43
chr12_-_24493656	0.207	ENSMUST00000073088.2	Gm16372	predicted pseudogene 16372
chr2_-_76673039	0.207	ENSMUST00000002809.7	Fkbp7	FK506 binding protein 7
chr11_-_48816936	0.205	ENSMUST00000140800.1	Trim41	tripartite motif-containing 41
chr18_-_15063560	0.182	ENSMUST00000168989.1	Kctd1	potassium channel tetramerisation domain containing 1
chr13_-_106847267	0.181	ENSMUST00000057427.4	Lrrc70	leucine rich repeat containing 70
chr8_-_105484350	0.170	ENSMUST00000044286.5	Zdhhc1	zinc finger, DHHC domain containing 1
chr7_+_6371364	0.156	ENSMUST00000086323.4 ENSMUST00000108559.2	Zfp78	zinc finger protein 78
chr2_-_167043494	0.153	ENSMUST00000067584.6	Znfx1	zinc finger, NFX1-type containing 1
chrX_+_101383726	0.150	ENSMUST00000119190.1	Gjb1	gap junction protein, beta 1
chr7_-_30194150	0.150	ENSMUST00000126116.1	Capns1	calpain, small subunit 1
chr8_+_70042768	0.148	ENSMUST00000011450.6	Sugp1	SURP and G patch domain containing 1
chr1_+_87403705	0.142	ENSMUST00000172736.1	Gigyf2	GRB10 interacting GYF protein 2
chr2_-_125723387	0.136	ENSMUST00000042246.7	Shc4	SHC (Src homology 2 domain containing) family, member 4
chr9_-_50617228	0.133	ENSMUST00000147671.1 ENSMUST00000145139.1 ENSMUST00000155435.1	AU019823	expressed sequence AU019823
chr1_-_126830632	0.121	ENSMUST00000112583.1 ENSMUST00000094609.3	Nckap5	NCK-associated protein 5
chr12_+_76837408	0.118	ENSMUST00000041008.9	Fntb	farnesyltransferase, CAAX box, beta
chr9_+_46273064	0.112	ENSMUST00000156440.1 ENSMUST00000034583.6 ENSMUST00000114552.3	Zfp259	zinc finger protein 259
chr11_-_48817332	0.110	ENSMUST00000047145.7	Trim41	tripartite motif-containing 41
chr15_-_81400043	0.103	ENSMUST00000172107.1 ENSMUST00000169204.1 ENSMUST00000163382.1	St13	suppression of tumorigenicity 13
chr4_-_143299498	0.099	ENSMUST00000030317.7	Pdpn	podoplanin
chr8_-_70042685	0.089	ENSMUST00000168013.2 ENSMUST00000050561.6	Mau2	MAU2 chromatid cohesion factor homolog (C. elegans)
chr2_+_91255954	0.084	ENSMUST00000134699.1	Pacsin3	protein kinase C and casein kinase substrate in neurons 3
chr16_-_32247152	0.081	ENSMUST00000042732.5	Fbxo45	F-box protein 45
chr17_+_8165501	0.078	ENSMUST00000097419.3 ENSMUST00000024636.8	Fgfr1op	Fgfr1 oncogene partner
chr16_-_91044473	0.074	ENSMUST00000118522.1	Paxbp1	PAX3 and PAX7 binding protein 1
chr7_+_30553263	0.071	ENSMUST00000044048.7	Hspb6	heat shock protein, alpha-crystallin-related, B6
chr11_+_31872100	0.065	ENSMUST00000020543.6 ENSMUST00000109412.2	Cpeb4	cytoplasmic polyadenylation element binding protein 4
chr15_+_12117813	0.056	ENSMUST00000122941.1	Zfr	zinc finger RNA binding protein
chr6_-_59024340	0.050	ENSMUST00000173193.1	Fam13a	family with sequence similarity 13, member A
chr6_+_21949571	0.044	ENSMUST00000031680.3 ENSMUST00000115389.1 ENSMUST00000151473.1	Ing3	inhibitor of growth family, member 3
chr7_+_130577334	0.025	ENSMUST00000059145.7 ENSMUST00000084513.4	Tacc2	transforming, acidic coiled-coil containing protein 2
chr6_-_59024470	0.022	ENSMUST00000089860.5	Fam13a	family with sequence similarity 13, member A
chr1_-_126830786	0.014	ENSMUST00000162646.1	Nckap5	NCK-associated protein 5
chr11_+_101425068	0.008	ENSMUST00000040561.5	Rundc1	RUN domain containing 1
chr10_-_83648631	0.007	ENSMUST00000146876.2 ENSMUST00000176294.1	Appl2	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.7	18.5	GO:0070327	thyroid hormone transport(GO:0070327)
1.3	4.0	GO:0001928	regulation of exocyst assembly(GO:0001928)
1.2	4.6	GO:0032914	positive regulation of transforming growth factor beta1 production(GO:0032914)
1.1	2.1	GO:1904425	negative regulation of GTP binding(GO:1904425)
0.9	2.8	GO:0003100	regulation of systemic arterial blood pressure by endothelin(GO:0003100) regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900)
0.7	4.9	GO:0032534	regulation of microvillus assembly(GO:0032534)
0.6	1.9	GO:0006601	creatine biosynthetic process(GO:0006601)
0.5	2.1	GO:1904048	negative regulation of synaptic vesicle recycling(GO:1903422) regulation of spontaneous neurotransmitter secretion(GO:1904048)
0.5	2.0	GO:0033024	mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.5	1.4	GO:0048687	positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691)
0.4	3.1	GO:0014819	regulation of skeletal muscle contraction(GO:0014819)
0.4	0.8	GO:0055099	response to high density lipoprotein particle(GO:0055099)
0.4	2.7	GO:0070494	regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.3	2.5	GO:0005513	detection of calcium ion(GO:0005513)
0.3	1.5	GO:1901843	positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.3	0.9	GO:1902336	neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190) positive regulation of retinal ganglion cell axon guidance(GO:1902336)
0.3	0.8	GO:0002946	tRNA C5-cytosine methylation(GO:0002946)
0.2	1.0	GO:1903031	regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.2	4.2	GO:0006958	complement activation, classical pathway(GO:0006958)
0.2	1.5	GO:0043615	astrocyte cell migration(GO:0043615)
0.1	0.4	GO:0006931	substrate-dependent cell migration, cell attachment to substrate(GO:0006931) calcium-independent cell-matrix adhesion(GO:0007161) transforming growth factor-beta secretion(GO:0038044)
0.1	0.5	GO:0071475	cellular hyperosmotic salinity response(GO:0071475)
0.1	2.3	GO:0033169	histone H3-K9 demethylation(GO:0033169)
0.1	0.7	GO:0003406	retinal pigment epithelium development(GO:0003406)
0.1	0.6	GO:0046684	response to pyrethroid(GO:0046684)
0.1	1.0	GO:0050882	voluntary musculoskeletal movement(GO:0050882)
0.1	0.4	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.1	0.9	GO:2000653	regulation of genetic imprinting(GO:2000653)
0.1	0.6	GO:0097264	self proteolysis(GO:0097264)
0.1	1.1	GO:0015937	coenzyme A biosynthetic process(GO:0015937)
0.1	0.7	GO:0060355	positive regulation of cell adhesion molecule production(GO:0060355)
0.1	0.3	GO:1901731	positive regulation of platelet aggregation(GO:1901731)
0.1	0.6	GO:0048752	semicircular canal morphogenesis(GO:0048752)
0.1	2.1	GO:0032728	positive regulation of interferon-beta production(GO:0032728)
0.1	0.3	GO:0000429	carbon catabolite regulation of transcription from RNA polymerase II promoter(GO:0000429) carbon catabolite activation of transcription from RNA polymerase II promoter(GO:0000436)
0.0	0.4	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	0.2	GO:0038018	Wnt receptor catabolic process(GO:0038018)
0.0	0.7	GO:0003094	glomerular filtration(GO:0003094)
0.0	0.1	GO:0018343	protein farnesylation(GO:0018343)
0.0	0.6	GO:0032515	negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0	0.7	GO:0002244	hematopoietic progenitor cell differentiation(GO:0002244)
0.0	0.2	GO:0090166	Golgi disassembly(GO:0090166)
0.0	0.7	GO:0018345	protein palmitoylation(GO:0018345)
0.0	0.4	GO:0010155	regulation of proton transport(GO:0010155)
0.0	0.2	GO:0031468	nuclear envelope reassembly(GO:0031468)
0.0	0.2	GO:0015868	purine ribonucleotide transport(GO:0015868)
0.0	0.4	GO:0035036	binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036)
0.0	2.7	GO:0006457	protein folding(GO:0006457)
0.0	0.5	GO:0001945	lymph vessel development(GO:0001945)
0.0	0.4	GO:0097320	membrane tubulation(GO:0097320)
0.0	3.5	GO:0006470	protein dephosphorylation(GO:0006470)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.3	10.0	GO:0030934	collagen type XII trimer(GO:0005595) anchoring collagen complex(GO:0030934)
0.4	4.6	GO:0098643	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.2	2.1	GO:0048787	presynaptic active zone membrane(GO:0048787)
0.1	0.4	GO:0005577	fibrinogen complex(GO:0005577)
0.1	0.5	GO:0043564	Ku70:Ku80 complex(GO:0043564)
0.1	4.6	GO:0005581	collagen trimer(GO:0005581)
0.1	3.1	GO:0005790	smooth endoplasmic reticulum(GO:0005790)
0.1	0.4	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.1	0.9	GO:0016010	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0	0.4	GO:0070369	beta-catenin-TCF7L2 complex(GO:0070369)
0.0	0.9	GO:0012507	ER to Golgi transport vesicle membrane(GO:0012507)
0.0	0.7	GO:0031045	dense core granule(GO:0031045)
0.0	0.6	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
0.0	0.1	GO:0005965	protein farnesyltransferase complex(GO:0005965)
0.0	0.2	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.0	0.3	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.0	2.4	GO:0009925	basal plasma membrane(GO:0009925)
0.0	2.7	GO:0005901	caveola(GO:0005901)
0.0	1.0	GO:0035371	microtubule plus-end(GO:0035371)
0.0	0.3	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.0	1.7	GO:0005758	mitochondrial intermembrane space(GO:0005758)
0.0	2.3	GO:0000118	histone deacetylase complex(GO:0000118)
0.0	4.8	GO:0009897	external side of plasma membrane(GO:0009897)
0.0	0.2	GO:0000815	ESCRT III complex(GO:0000815)
0.0	2.0	GO:0030175	filopodium(GO:0030175)
0.0	1.4	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	1.8	GO:0008076	voltage-gated potassium channel complex(GO:0008076)
0.0	16.0	GO:0005615	extracellular space(GO:0005615)
0.0	0.1	GO:1990635	proximal dendrite(GO:1990635)
0.0	0.2	GO:0005922	connexon complex(GO:0005922)
0.0	3.0	GO:0009986	cell surface(GO:0009986)
0.0	0.6	GO:0008287	protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0	1.7	GO:0005741	mitochondrial outer membrane(GO:0005741)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.1	18.5	GO:0070324	thyroid hormone binding(GO:0070324)
0.9	2.8	GO:0004517	nitric-oxide synthase activity(GO:0004517)
0.7	2.7	GO:0005008	hepatocyte growth factor-activated receptor activity(GO:0005008)
0.4	3.1	GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.3	2.0	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.3	0.9	GO:0043183	vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.3	1.4	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.3	0.8	GO:0030226	apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.3	3.0	GO:0070097	delta-catenin binding(GO:0070097)
0.2	4.0	GO:0030275	LRR domain binding(GO:0030275)
0.2	0.7	GO:0030348	syntaxin-3 binding(GO:0030348)
0.1	2.3	GO:0042809	vitamin D receptor binding(GO:0042809)
0.1	1.8	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.1	7.7	GO:0005518	collagen binding(GO:0005518)
0.1	2.0	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.1	0.4	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1	0.8	GO:0016428	tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.1	1.9	GO:0016769	transferase activity, transferring nitrogenous groups(GO:0016769)
0.1	3.4	GO:0005484	SNAP receptor activity(GO:0005484)
0.1	0.4	GO:0045340	mercury ion binding(GO:0045340)
0.1	0.4	GO:0008556	sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.1	0.6	GO:0008329	signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.1	2.4	GO:0001671	ATPase activator activity(GO:0001671)
0.1	0.4	GO:0004065	arylsulfatase activity(GO:0004065)
0.1	0.4	GO:0035242	protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.1	0.7	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.1	0.3	GO:0033142	progesterone receptor binding(GO:0033142)
0.1	1.5	GO:0048020	CCR chemokine receptor binding(GO:0048020)
0.1	0.7	GO:0005242	inward rectifier potassium channel activity(GO:0005242)
0.1	0.5	GO:0051575	5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0	0.5	GO:0019855	calcium channel inhibitor activity(GO:0019855)
0.0	1.1	GO:0016881	acid-amino acid ligase activity(GO:0016881)
0.0	0.3	GO:0005127	ciliary neurotrophic factor receptor binding(GO:0005127)
0.0	0.4	GO:0050815	phosphoserine binding(GO:0050815)
0.0	0.1	GO:0004660	protein farnesyltransferase activity(GO:0004660)
0.0	0.6	GO:0031402	sodium ion binding(GO:0031402)
0.0	0.3	GO:0015250	water channel activity(GO:0015250)
0.0	0.7	GO:0019707	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0	0.4	GO:0045295	gamma-catenin binding(GO:0045295)
0.0	0.4	GO:0005044	scavenger receptor activity(GO:0005044)
0.0	0.1	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.0	2.2	GO:0003697	single-stranded DNA binding(GO:0003697)
0.0	1.9	GO:0042626	ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0	0.2	GO:0005243	gap junction channel activity(GO:0005243)
0.0	0.7	GO:0030145	manganese ion binding(GO:0030145)
0.0	2.1	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0	0.2	GO:0005528	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	3.7	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0	0.5	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.1	GO:0005212	structural constituent of eye lens(GO:0005212)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	18.5	PID_HNF3B_PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.2	12.7	PID_SYNDECAN_1_PATHWAY	Syndecan-1-mediated signaling events
0.1	4.6	NABA_PROTEOGLYCANS	Genes encoding proteoglycans
0.1	2.8	PID_FRA_PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1	0.9	PID_VEGF_VEGFR_PATHWAY	VEGF and VEGFR signaling network
0.1	4.0	PID_FGF_PATHWAY	FGF signaling pathway
0.0	1.8	PID_RXR_VDR_PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.0	4.9	NABA_ECM_AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	1.5	PID_IL12_2PATHWAY	IL12-mediated signaling events
0.0	0.4	PID_LYMPH_ANGIOGENESIS_PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.0	1.4	PID_SHP2_PATHWAY	SHP2 signaling
0.0	3.4	NABA_ECM_GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	0.5	PID_DNA_PK_PATHWAY	DNA-PK pathway in nonhomologous end joining
0.0	0.4	PID_A6B1_A6B4_INTEGRIN_PATHWAY	a6b1 and a6b4 Integrin signaling
0.0	0.7	SIG_CD40PATHWAYMAP	Genes related to CD40 signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	4.2	REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.5	4.6	REACTOME_KERATAN_SULFATE_DEGRADATION	Genes involved in Keratan sulfate degradation
0.3	18.5	REACTOME_AMYLOIDS	Genes involved in Amyloids
0.2	2.8	REACTOME_BOTULINUM_NEUROTOXICITY	Genes involved in Botulinum neurotoxicity
0.2	10.0	REACTOME_COLLAGEN_FORMATION	Genes involved in Collagen formation
0.1	2.8	REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1	4.0	REACTOME_NCAM1_INTERACTIONS	Genes involved in NCAM1 interactions
0.1	1.9	REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.1	1.1	REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.1	3.1	REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1	0.9	REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.1	0.8	REACTOME_HDL_MEDIATED_LIPID_TRANSPORT	Genes involved in HDL-mediated lipid transport
0.1	2.7	REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING	Genes involved in Sema4D in semaphorin signaling
0.1	1.5	REACTOME_CGMP_EFFECTS	Genes involved in cGMP effects
0.1	1.5	REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.1	5.0	REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.6	REACTOME_FGFR1_LIGAND_BINDING_AND_ACTIVATION	Genes involved in FGFR1 ligand binding and activation
0.0	0.4	REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.0	0.5	REACTOME_INTEGRATION_OF_PROVIRUS	Genes involved in Integration of provirus
0.0	0.4	REACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0	0.4	REACTOME_RAF_MAP_KINASE_CASCADE	Genes involved in RAF/MAP kinase cascade
0.0	0.4	REACTOME_N_GLYCAN_ANTENNAE_ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.7	REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	0.2	REACTOME_GAP_JUNCTION_ASSEMBLY	Genes involved in Gap junction assembly
0.0	0.4	REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES	Genes involved in Ion transport by P-type ATPases

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