Motif ID: Pitx1

Z-value: 0.873


Transcription factors associated with Pitx1:

Gene SymbolEntrez IDGene Name
Pitx1 ENSMUSG00000021506.7 Pitx1



Activity profile for motif Pitx1.

activity profile for motif Pitx1


Sorted Z-values histogram for motif Pitx1

Sorted Z-values for motif Pitx1



Network of associatons between targets according to the STRING database.



First level regulatory network of Pitx1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_93913678 13.013 ENSMUST00000093769.5
Magi1
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr13_-_97747373 10.445 ENSMUST00000123535.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr13_-_97747399 10.433 ENSMUST00000144993.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr16_-_46010212 9.323 ENSMUST00000130481.1
Plcxd2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr10_-_92165159 9.004 ENSMUST00000182567.1
ENSMUST00000181604.2
ENSMUST00000181213.1
Rmst


rhabdomyosarcoma 2 associated transcript (non-coding RNA)


chr1_-_155232710 8.669 ENSMUST00000035914.3
BC034090
cDNA sequence BC034090
chr8_+_127064022 8.385 ENSMUST00000160272.1
ENSMUST00000079777.5
ENSMUST00000162907.1
Pard3


par-3 (partitioning defective 3) homolog (C. elegans)


chr8_+_127063893 7.693 ENSMUST00000162309.1
Pard3
par-3 (partitioning defective 3) homolog (C. elegans)
chr2_+_102658640 7.614 ENSMUST00000080210.3
Slc1a2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr4_-_155010984 6.885 ENSMUST00000105631.2
ENSMUST00000139976.2
ENSMUST00000145662.2
Plch2


phospholipase C, eta 2


chr14_-_54926784 6.859 ENSMUST00000022813.6
Efs
embryonal Fyn-associated substrate
chr14_-_31640878 6.663 ENSMUST00000167066.1
ENSMUST00000127204.2
ENSMUST00000022437.8
Hacl1


2-hydroxyacyl-CoA lyase 1


chr5_+_3343893 6.611 ENSMUST00000165117.1
Cdk6
cyclin-dependent kinase 6
chr17_+_75005523 6.415 ENSMUST00000001927.5
Ltbp1
latent transforming growth factor beta binding protein 1
chr4_-_41697040 6.402 ENSMUST00000102962.3
ENSMUST00000084701.5
Cntfr

ciliary neurotrophic factor receptor

chr7_-_4752972 6.350 ENSMUST00000183971.1
ENSMUST00000182173.1
ENSMUST00000182738.1
ENSMUST00000184143.1
ENSMUST00000182111.1
ENSMUST00000182048.1
ENSMUST00000063324.7
Cox6b2






cytochrome c oxidase subunit VIb polypeptide 2






chr9_-_37433138 6.241 ENSMUST00000115038.1
Robo3
roundabout homolog 3 (Drosophila)
chr6_-_124840192 6.100 ENSMUST00000024206.5
Gnb3
guanine nucleotide binding protein (G protein), beta 3
chr2_+_119325784 6.095 ENSMUST00000102517.3
Dll4
delta-like 4 (Drosophila)
chr5_+_3344194 5.971 ENSMUST00000042410.4
Cdk6
cyclin-dependent kinase 6
chr14_-_118052235 5.760 ENSMUST00000022725.2
Dct
dopachrome tautomerase
chr2_+_38341068 5.717 ENSMUST00000133661.1
Lhx2
LIM homeobox protein 2
chr19_-_47919269 5.557 ENSMUST00000095998.5
Itprip
inositol 1,4,5-triphosphate receptor interacting protein
chr4_+_116708687 5.461 ENSMUST00000135499.1
Ccdc163
coiled-coil domain containing 163
chr14_+_26122609 5.265 ENSMUST00000100810.6
Duxbl2
doubl homeobox B-like 2
chr2_-_18048784 5.238 ENSMUST00000142856.1
Skida1
SKI/DACH domain containing 1
chr5_+_137641334 5.135 ENSMUST00000177466.1
ENSMUST00000166099.2
Sap25

sin3 associated polypeptide

chr9_+_58134535 4.902 ENSMUST00000128378.1
ENSMUST00000150820.1
ENSMUST00000167479.1
ENSMUST00000134450.1
Stra6



stimulated by retinoic acid gene 6



chr14_+_25983005 4.838 ENSMUST00000049793.8
Duxbl1
double homeobox B-like 1
chr9_+_50617516 4.206 ENSMUST00000141366.1
Pih1d2
PIH1 domain containing 2
chr4_-_42661893 4.156 ENSMUST00000108006.3
Il11ra2
interleukin 11 receptor, alpha chain 2
chr7_-_133015248 4.107 ENSMUST00000169570.1
Ctbp2
C-terminal binding protein 2
chr2_-_64097994 4.052 ENSMUST00000131615.2
Fign
fidgetin
chr7_-_15879844 3.733 ENSMUST00000172758.1
ENSMUST00000044434.6
Crx

cone-rod homeobox containing gene

chr19_-_12765447 3.714 ENSMUST00000112933.1
Cntf
ciliary neurotrophic factor
chr10_+_18407658 3.688 ENSMUST00000037341.7
Nhsl1
NHS-like 1
chr1_-_165934900 3.648 ENSMUST00000069609.5
ENSMUST00000111427.2
ENSMUST00000111426.4
Pou2f1


POU domain, class 2, transcription factor 1


chr3_+_89520152 3.490 ENSMUST00000000811.7
Kcnn3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr4_-_133968611 3.475 ENSMUST00000102552.1
Hmgn2
high mobility group nucleosomal binding domain 2
chr10_-_80421847 3.417 ENSMUST00000156244.1
Tcf3
transcription factor 3
chr4_-_52497244 3.380 ENSMUST00000114578.4
Vma21-ps
VMA21 vacuolar H+-ATPase homolog (S. cerevisiae), pseudogene
chr10_-_127288851 3.375 ENSMUST00000156208.1
ENSMUST00000026476.6
Mbd6

methyl-CpG binding domain protein 6

chr1_-_119648903 3.311 ENSMUST00000163147.1
ENSMUST00000052404.6
ENSMUST00000027632.7
Epb4.1l5


erythrocyte protein band 4.1-like 5


chr2_-_18048347 3.252 ENSMUST00000066885.5
Skida1
SKI/DACH domain containing 1
chr13_+_3361029 3.231 ENSMUST00000179981.1
Gm16505
predicted gene 16505
chr2_+_125068118 3.131 ENSMUST00000070353.3
Slc24a5
solute carrier family 24, member 5
chr15_+_4375462 3.086 ENSMUST00000061925.4
Plcxd3
phosphatidylinositol-specific phospholipase C, X domain containing 3
chr14_+_67745229 3.085 ENSMUST00000111095.2
Gnrh1
gonadotropin releasing hormone 1
chr1_-_51915968 3.003 ENSMUST00000046390.7
Myo1b
myosin IB
chrX_+_169879596 2.998 ENSMUST00000112105.1
ENSMUST00000078947.5
Mid1

midline 1

chr10_-_127288999 2.979 ENSMUST00000119078.1
Mbd6
methyl-CpG binding domain protein 6
chr4_+_144893077 2.967 ENSMUST00000154208.1
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr1_-_136230289 2.932 ENSMUST00000150163.1
ENSMUST00000144464.1
5730559C18Rik

RIKEN cDNA 5730559C18 gene

chr7_+_101969796 2.874 ENSMUST00000084852.5
Numa1
nuclear mitotic apparatus protein 1
chr4_+_144892813 2.857 ENSMUST00000105744.1
ENSMUST00000171001.1
Dhrs3

dehydrogenase/reductase (SDR family) member 3

chr4_+_144893127 2.802 ENSMUST00000142808.1
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr7_+_30553263 2.778 ENSMUST00000044048.7
Hspb6
heat shock protein, alpha-crystallin-related, B6
chr4_-_140246751 2.755 ENSMUST00000039331.8
Igsf21
immunoglobulin superfamily, member 21
chr11_+_23256566 2.747 ENSMUST00000136235.1
Xpo1
exportin 1, CRM1 homolog (yeast)
chr17_-_15375969 2.718 ENSMUST00000014917.7
Dll1
delta-like 1 (Drosophila)
chr17_+_35861318 2.698 ENSMUST00000074259.8
ENSMUST00000174873.1
Nrm

nurim (nuclear envelope membrane protein)

chr10_-_127189981 2.667 ENSMUST00000019611.7
Arhgef25
Rho guanine nucleotide exchange factor (GEF) 25
chr7_-_133123770 2.640 ENSMUST00000164896.1
ENSMUST00000171968.1
Ctbp2

C-terminal binding protein 2

chr3_-_84270782 2.624 ENSMUST00000054990.4
Trim2
tripartite motif-containing 2
chr10_+_25408346 2.516 ENSMUST00000092645.6
Epb4.1l2
erythrocyte protein band 4.1-like 2
chr9_-_100486788 2.471 ENSMUST00000098458.3
Il20rb
interleukin 20 receptor beta
chr6_+_3993776 2.421 ENSMUST00000031673.5
Gngt1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr14_+_27039001 2.407 ENSMUST00000035336.3
Il17rd
interleukin 17 receptor D
chr18_-_15718046 2.393 ENSMUST00000053017.6
Chst9
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
chr6_+_136954521 2.391 ENSMUST00000137768.1
Pde6h
phosphodiesterase 6H, cGMP-specific, cone, gamma
chr6_+_29361410 2.372 ENSMUST00000156163.1
Calu
calumenin
chr8_+_78509319 2.363 ENSMUST00000034111.8
Slc10a7
solute carrier family 10 (sodium/bile acid cotransporter family), member 7
chr5_-_5694559 2.348 ENSMUST00000115426.2
Steap2
six transmembrane epithelial antigen of prostate 2
chr13_+_113035111 2.303 ENSMUST00000180543.1
ENSMUST00000181568.1
ENSMUST00000109244.2
ENSMUST00000181117.1
ENSMUST00000181741.1
Cdc20b




cell division cycle 20B




chr3_+_55782500 2.265 ENSMUST00000075422.4
Mab21l1
mab-21-like 1 (C. elegans)
chr1_+_157458554 2.256 ENSMUST00000046743.4
ENSMUST00000119891.1
BC026585

cDNA sequence BC026585

chr7_+_16781341 2.214 ENSMUST00000108496.2
Slc1a5
solute carrier family 1 (neutral amino acid transporter), member 5
chr2_+_69670100 2.185 ENSMUST00000100050.3
Klhl41
kelch-like 41
chr4_-_141053660 2.185 ENSMUST00000040222.7
Crocc
ciliary rootlet coiled-coil, rootletin
chr5_-_134456702 2.096 ENSMUST00000073161.5
ENSMUST00000171794.2
ENSMUST00000111245.2
ENSMUST00000100654.3
ENSMUST00000167084.2
ENSMUST00000100652.3
ENSMUST00000100650.3
ENSMUST00000074114.5
Gtf2ird1







general transcription factor II I repeat domain-containing 1







chr15_+_36179530 2.002 ENSMUST00000171205.1
Spag1
sperm associated antigen 1
chr3_+_88616133 1.982 ENSMUST00000176500.1
ENSMUST00000177498.1
Arhgef2

rho/rac guanine nucleotide exchange factor (GEF) 2

chrX_-_100626568 1.977 ENSMUST00000015812.5
Pdzd11
PDZ domain containing 11
chrX_+_7909542 1.967 ENSMUST00000086274.2
Gm10490
predicted gene 10490
chr9_+_31030621 1.927 ENSMUST00000115222.2
Zbtb44
zinc finger and BTB domain containing 44
chr18_+_36281069 1.896 ENSMUST00000051301.3
Pura
purine rich element binding protein A
chr3_-_33083016 1.896 ENSMUST00000078226.3
ENSMUST00000108224.1
Pex5l

peroxisomal biogenesis factor 5-like

chr1_-_170110491 1.830 ENSMUST00000027985.2
Ddr2
discoidin domain receptor family, member 2
chr5_+_64159429 1.807 ENSMUST00000043893.6
Tbc1d1
TBC1 domain family, member 1
chr4_+_99829437 1.794 ENSMUST00000124547.1
ENSMUST00000106994.1
Efcab7

EF-hand calcium binding domain 7

chr9_-_50617428 1.786 ENSMUST00000131351.1
ENSMUST00000171462.1
AU019823

expressed sequence AU019823

chr9_+_35423582 1.764 ENSMUST00000154652.1
Cdon
cell adhesion molecule-related/down-regulated by oncogenes
chr9_-_54501496 1.700 ENSMUST00000118600.1
ENSMUST00000118163.1
Dmxl2

Dmx-like 2

chr11_+_116657106 1.620 ENSMUST00000116318.2
Gm11744
predicted gene 11744
chr7_-_25398697 1.594 ENSMUST00000105177.2
ENSMUST00000149349.1
Lipe

lipase, hormone sensitive

chr10_-_14718191 1.527 ENSMUST00000020016.4
Gje1
gap junction protein, epsilon 1
chr14_+_59201418 1.505 ENSMUST00000140136.2
ENSMUST00000142326.1
Rcbtb1

regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1

chr7_-_127725616 1.497 ENSMUST00000076091.2
Ctf2
cardiotrophin 2
chr9_+_109875541 1.438 ENSMUST00000094324.3
Cdc25a
cell division cycle 25A
chr1_+_167598450 1.426 ENSMUST00000111386.1
ENSMUST00000111384.1
Rxrg

retinoid X receptor gamma

chr11_-_51756378 1.407 ENSMUST00000109092.1
ENSMUST00000064297.4
ENSMUST00000109097.2
Sec24a


Sec24 related gene family, member A (S. cerevisiae)


chr17_+_35861343 1.400 ENSMUST00000172931.1
Nrm
nurim (nuclear envelope membrane protein)
chr4_+_15881255 1.397 ENSMUST00000029876.1
Calb1
calbindin 1
chrX_+_74424534 1.382 ENSMUST00000135165.1
ENSMUST00000114128.1
ENSMUST00000114133.2
ENSMUST00000004330.3
Ikbkg



inhibitor of kappaB kinase gamma



chr17_+_56770258 1.341 ENSMUST00000168666.2
Prr22
proline rich 22
chr10_-_117376922 1.339 ENSMUST00000177145.1
ENSMUST00000176670.1
Cpsf6

cleavage and polyadenylation specific factor 6

chr6_+_122707489 1.319 ENSMUST00000112581.1
ENSMUST00000112580.1
ENSMUST00000012540.4
Nanog


Nanog homeobox


chr1_+_74542881 1.293 ENSMUST00000113749.1
ENSMUST00000067916.6
ENSMUST00000113745.1
ENSMUST00000113747.1
ENSMUST00000113750.1
Plcd4




phospholipase C, delta 4




chr1_+_167598384 1.291 ENSMUST00000015987.3
Rxrg
retinoid X receptor gamma
chr4_-_141053704 1.276 ENSMUST00000102491.3
Crocc
ciliary rootlet coiled-coil, rootletin
chr3_-_113630068 1.261 ENSMUST00000092154.3
ENSMUST00000106536.1
ENSMUST00000106535.1
Rnpc3


RNA-binding region (RNP1, RRM) containing 3


chr11_-_100472725 1.256 ENSMUST00000056665.3
Klhl11
kelch-like 11
chr2_+_28506095 1.243 ENSMUST00000074761.4
Gm10134
predicted gene 10134
chr17_+_7925990 1.228 ENSMUST00000036370.7
Tagap
T cell activation Rho GTPase activating protein
chr10_-_22149270 1.214 ENSMUST00000179054.1
ENSMUST00000069372.6
E030030I06Rik

RIKEN cDNA E030030I06 gene

chr5_+_8422831 1.197 ENSMUST00000066921.3
Slc25a40
solute carrier family 25, member 40
chr8_-_111259192 1.184 ENSMUST00000169020.1
ENSMUST00000003404.8
Glg1

golgi apparatus protein 1

chr11_-_69398226 1.159 ENSMUST00000050140.5
Tmem88
transmembrane protein 88
chr1_-_158958367 1.142 ENSMUST00000159861.2
Pappa2
pappalysin 2
chrX_+_74424632 1.141 ENSMUST00000114129.2
ENSMUST00000132749.1
Ikbkg

inhibitor of kappaB kinase gamma

chr7_+_13398115 1.135 ENSMUST00000005791.7
Cabp5
calcium binding protein 5
chr14_+_52110939 1.108 ENSMUST00000111600.4
Rpgrip1
retinitis pigmentosa GTPase regulator interacting protein 1
chr5_+_8422908 1.084 ENSMUST00000170496.1
Slc25a40
solute carrier family 25, member 40
chr9_-_50617228 1.056 ENSMUST00000147671.1
ENSMUST00000145139.1
ENSMUST00000155435.1
AU019823


expressed sequence AU019823


chr5_-_92435219 1.054 ENSMUST00000038514.8
Nup54
nucleoporin 54
chrX_+_169685191 1.031 ENSMUST00000112104.1
ENSMUST00000112107.1
Mid1

midline 1

chr18_+_60925644 1.018 ENSMUST00000115297.1
Camk2a
calcium/calmodulin-dependent protein kinase II alpha
chr2_+_23068168 1.014 ENSMUST00000028121.7
ENSMUST00000114523.2
ENSMUST00000144088.1
Acbd5


acyl-Coenzyme A binding domain containing 5


chr13_-_116309639 1.001 ENSMUST00000036060.6
Isl1
ISL1 transcription factor, LIM/homeodomain
chr1_-_191907527 0.998 ENSMUST00000069573.5
1700034H15Rik
RIKEN cDNA 1700034H15 gene
chr14_+_64588112 0.997 ENSMUST00000181808.1
A930011O12Rik
RIKEN cDNA A930011O12 gene
chr8_-_11678728 0.885 ENSMUST00000033906.4
1700016D06Rik
RIKEN cDNA 1700016D06 gene
chr6_-_122340200 0.859 ENSMUST00000159384.1
Phc1
polyhomeotic-like 1 (Drosophila)
chr17_-_35132050 0.858 ENSMUST00000025249.6
Apom
apolipoprotein M
chr10_-_117376955 0.846 ENSMUST00000069168.6
ENSMUST00000176686.1
Cpsf6

cleavage and polyadenylation specific factor 6

chr10_-_6980376 0.821 ENSMUST00000105617.1
Ipcef1
interaction protein for cytohesin exchange factors 1
chr5_+_137787769 0.816 ENSMUST00000035852.7
Zcwpw1
zinc finger, CW type with PWWP domain 1
chr17_+_35089229 0.810 ENSMUST00000007251.7
Abhd16a
abhydrolase domain containing 16A
chr11_+_95010277 0.803 ENSMUST00000124735.1
Samd14
sterile alpha motif domain containing 14
chr15_+_18818895 0.762 ENSMUST00000166873.2
Cdh10
cadherin 10
chr12_+_37108533 0.760 ENSMUST00000041183.5
Meox2
mesenchyme homeobox 2
chr10_+_19951055 0.758 ENSMUST00000152533.1
Map3k5
mitogen-activated protein kinase kinase kinase 5
chr11_+_115900125 0.730 ENSMUST00000142089.1
ENSMUST00000131566.1
Smim5

small integral membrane protein 5

chr2_+_91259822 0.723 ENSMUST00000138470.1
Pacsin3
protein kinase C and casein kinase substrate in neurons 3
chr11_+_23256001 0.708 ENSMUST00000020538.6
ENSMUST00000109551.1
ENSMUST00000102870.1
ENSMUST00000102869.1
Xpo1



exportin 1, CRM1 homolog (yeast)



chr9_-_99876147 0.703 ENSMUST00000054819.8
Sox14
SRY-box containing gene 14
chr1_-_44218952 0.678 ENSMUST00000054801.3
Mettl21e
methyltransferase like 21E
chr3_-_57294880 0.635 ENSMUST00000171384.1
Tm4sf1
transmembrane 4 superfamily member 1
chr3_+_129199960 0.616 ENSMUST00000173645.2
Pitx2
paired-like homeodomain transcription factor 2
chr18_+_42394539 0.604 ENSMUST00000025374.3
Pou4f3
POU domain, class 4, transcription factor 3
chr11_-_106920359 0.574 ENSMUST00000167787.1
ENSMUST00000092517.2
Smurf2

SMAD specific E3 ubiquitin protein ligase 2

chr11_+_4637734 0.568 ENSMUST00000109930.2
ENSMUST00000070257.7
Ascc2

activating signal cointegrator 1 complex subunit 2

chr7_-_98656530 0.550 ENSMUST00000038359.4
2210018M11Rik
RIKEN cDNA 2210018M11 gene
chr17_-_23586214 0.516 ENSMUST00000115516.3
Zfp13
zinc finger protein 13
chr11_+_70459940 0.509 ENSMUST00000147289.1
ENSMUST00000126105.1
Zmynd15

zinc finger, MYND-type containing 15

chr15_+_102331700 0.509 ENSMUST00000113682.2
ENSMUST00000001331.6
ENSMUST00000171244.1
Myg1


melanocyte proliferating gene 1


chr7_+_35802593 0.508 ENSMUST00000052454.2
E130304I02Rik
RIKEN cDNA E130304I02 gene
chr6_+_4902913 0.498 ENSMUST00000175889.1
ENSMUST00000168998.2
Ppp1r9a

protein phosphatase 1, regulatory (inhibitor) subunit 9A

chr11_+_69995874 0.491 ENSMUST00000101526.2
Phf23
PHD finger protein 23
chr11_+_87578384 0.475 ENSMUST00000107962.1
ENSMUST00000122067.1
Sept4

septin 4

chr11_+_69995777 0.465 ENSMUST00000018716.3
Phf23
PHD finger protein 23
chr1_-_13372434 0.457 ENSMUST00000081713.4
Ncoa2
nuclear receptor coactivator 2
chrM_+_8600 0.432 ENSMUST00000082409.1
mt-Co3
mitochondrially encoded cytochrome c oxidase III
chr11_+_82388900 0.392 ENSMUST00000054245.4
ENSMUST00000092852.2
Tmem132e

transmembrane protein 132E

chr13_+_89540636 0.382 ENSMUST00000022108.7
Hapln1
hyaluronan and proteoglycan link protein 1
chr3_+_103809520 0.379 ENSMUST00000076599.1
ENSMUST00000106824.1
ENSMUST00000106823.1
ENSMUST00000047285.2
Ap4b1



adaptor-related protein complex AP-4, beta 1



chr9_+_107340593 0.379 ENSMUST00000042581.2
6430571L13Rik
RIKEN cDNA 6430571L13 gene
chr2_+_120476911 0.362 ENSMUST00000110716.1
ENSMUST00000028748.6
ENSMUST00000090028.5
ENSMUST00000110719.2
Capn3



calpain 3



chr4_+_84884418 0.358 ENSMUST00000169371.2
Cntln
centlein, centrosomal protein
chr2_-_23040137 0.354 ENSMUST00000091394.6
ENSMUST00000093171.6
Abi1

abl-interactor 1

chr7_-_80403315 0.341 ENSMUST00000147150.1
Furin
furin (paired basic amino acid cleaving enzyme)
chr2_-_101628930 0.332 ENSMUST00000099682.2
B230118H07Rik
RIKEN cDNA B230118H07 gene
chr16_-_91011093 0.330 ENSMUST00000170853.1
ENSMUST00000118390.2
Synj1

synaptojanin 1

chr2_-_23040177 0.325 ENSMUST00000114544.3
ENSMUST00000139038.1
ENSMUST00000126112.1
ENSMUST00000178908.1
ENSMUST00000078977.7
ENSMUST00000140164.1
ENSMUST00000149719.1
Abi1






abl-interactor 1






chr3_+_79884496 0.315 ENSMUST00000118853.1
Fam198b
family with sequence similarity 198, member B
chr3_-_33082004 0.262 ENSMUST00000108225.3
Pex5l
peroxisomal biogenesis factor 5-like
chr11_+_88047693 0.260 ENSMUST00000079866.4
Srsf1
serine/arginine-rich splicing factor 1
chr3_+_28781305 0.232 ENSMUST00000060500.7
Eif5a2
eukaryotic translation initiation factor 5A2
chr3_+_105973711 0.222 ENSMUST00000000573.2
Ovgp1
oviductal glycoprotein 1
chr11_-_100135928 0.194 ENSMUST00000107411.2
Krt15
keratin 15
chr13_+_59585259 0.194 ENSMUST00000168367.1
ENSMUST00000022038.7
ENSMUST00000166923.1
Naa35


N(alpha)-acetyltransferase 35, NatC auxiliary subunit


chr11_+_29718563 0.185 ENSMUST00000060992.5
Rtn4
reticulon 4
chr12_-_102439813 0.164 ENSMUST00000021607.8
Lgmn
legumain
chr9_-_110101010 0.161 ENSMUST00000062368.6
Dhx30
DEAH (Asp-Glu-Ala-His) box polypeptide 30
chr6_+_17749170 0.158 ENSMUST00000053148.7
ENSMUST00000115417.3
St7

suppression of tumorigenicity 7

chr1_+_87403705 0.152 ENSMUST00000172736.1
Gigyf2
GRB10 interacting GYF protein 2
chr18_-_25753852 0.137 ENSMUST00000025117.6
ENSMUST00000115816.2
Celf4

CUGBP, Elav-like family member 4

chr19_-_6077183 0.125 ENSMUST00000025711.5
ENSMUST00000160590.1
Vps51

vacuolar protein sorting 51 homolog (S. cerevisiae)

chr17_+_34969912 0.119 ENSMUST00000173680.1
Gm20481
predicted gene 20481
chr10_+_94198955 0.115 ENSMUST00000020209.9
ENSMUST00000179990.1
Ndufa12

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12

chr11_-_22982090 0.106 ENSMUST00000093270.5
ENSMUST00000071068.8
ENSMUST00000159081.1
ENSMUST00000160826.1
Commd1


RP23-242C19.7
COMM domain containing 1


UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 (B3gnt2), transcript variant 2, mRNA
chr6_+_4903298 0.096 ENSMUST00000035813.2
Ppp1r9a
protein phosphatase 1, regulatory (inhibitor) subunit 9A
chr3_+_103058302 0.059 ENSMUST00000029445.6
Nras
neuroblastoma ras oncogene
chr5_-_36695969 0.049 ENSMUST00000031091.9
ENSMUST00000140063.1
D5Ertd579e

DNA segment, Chr 5, ERATO Doi 579, expressed

chr9_-_108567336 0.011 ENSMUST00000074208.4
Ndufaf3
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 3
chr5_+_75574916 0.002 ENSMUST00000144270.1
ENSMUST00000005815.6
Kit

kit oncogene


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 2.7 GO:0060853 arterial endothelial cell fate commitment(GO:0060844) blood vessel endothelial cell fate commitment(GO:0060846) endothelial cell fate specification(GO:0060847) Notch signaling pathway involved in arterial endothelial cell fate commitment(GO:0060853) blood vessel endothelial cell fate specification(GO:0097101)
2.7 16.1 GO:0003383 apical constriction(GO:0003383)
2.0 6.1 GO:0072554 blood vessel lumenization(GO:0072554) negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
1.8 12.6 GO:0044838 cell quiescence(GO:0044838)
1.6 6.4 GO:0003360 brainstem development(GO:0003360)
1.6 3.1 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
1.3 6.7 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
1.2 6.2 GO:0061642 chemoattraction of axon(GO:0061642)
1.2 3.7 GO:0048687 positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691)
1.1 7.6 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
1.0 4.9 GO:0046864 retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865) alveolar primary septum development(GO:0061143)
1.0 5.8 GO:0006570 tyrosine metabolic process(GO:0006570)
0.9 3.5 GO:0032053 ciliary basal body organization(GO:0032053)
0.8 2.5 GO:0002865 immune response-inhibiting signal transduction(GO:0002765) negative regulation of acute inflammatory response to antigenic stimulus(GO:0002865)
0.8 8.6 GO:0042572 retinol metabolic process(GO:0042572)
0.8 3.1 GO:0033087 negative regulation of immature T cell proliferation(GO:0033087)
0.7 2.9 GO:1904778 regulation of metaphase plate congression(GO:0090235) regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.7 6.7 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.6 7.7 GO:0045199 maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.6 3.4 GO:0002326 B cell lineage commitment(GO:0002326)
0.6 2.2 GO:0015825 L-serine transport(GO:0015825)
0.5 1.6 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.5 3.6 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.5 2.3 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.4 4.0 GO:0035372 protein localization to microtubule(GO:0035372)
0.4 1.3 GO:1903225 regulation of endodermal cell fate specification(GO:0042663) negative regulation of endodermal cell differentiation(GO:1903225)
0.4 2.1 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.4 0.8 GO:0001757 somite specification(GO:0001757)
0.4 3.7 GO:0097475 motor neuron migration(GO:0097475)
0.4 2.2 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.4 1.1 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.3 2.7 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.3 1.0 GO:0032650 regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730) cardiac cell fate determination(GO:0060913)
0.3 0.9 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.3 2.9 GO:0070423 nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431)
0.3 1.4 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.3 1.4 GO:0072235 distal convoluted tubule development(GO:0072025) metanephric collecting duct development(GO:0072205) metanephric distal convoluted tubule development(GO:0072221) metanephric distal tubule development(GO:0072235)
0.3 0.8 GO:0046462 monoacylglycerol metabolic process(GO:0046462)
0.3 6.4 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.2 2.0 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.2 1.8 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.2 1.6 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.2 0.9 GO:0050748 negative regulation of lipoprotein metabolic process(GO:0050748)
0.2 1.0 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.2 1.9 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.2 1.7 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.2 2.8 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.2 0.6 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.2 2.5 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.2 5.6 GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.1 1.0 GO:0030242 pexophagy(GO:0030242)
0.1 3.5 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.1 0.5 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726)
0.1 4.1 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.1 0.6 GO:0021562 vestibulocochlear nerve development(GO:0021562)
0.1 0.4 GO:2001015 skeletal muscle satellite cell activation(GO:0014719) G1 to G0 transition involved in cell differentiation(GO:0070315) negative regulation of skeletal muscle cell differentiation(GO:2001015)
0.1 0.6 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.1 2.8 GO:0010667 negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.1 2.7 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.1 0.5 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.1 2.8 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.1 2.4 GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742) positive regulation of ERBB signaling pathway(GO:1901186)
0.1 0.3 GO:0090472 dibasic protein processing(GO:0090472)
0.1 0.5 GO:1904017 positive regulation of female receptivity(GO:0045925) response to Thyroglobulin triiodothyronine(GO:1904016) cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.1 18.7 GO:0016042 lipid catabolic process(GO:0016042)
0.1 0.2 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1 0.8 GO:1902170 cellular response to reactive nitrogen species(GO:1902170)
0.0 2.2 GO:0006378 mRNA polyadenylation(GO:0006378)
0.0 0.2 GO:0006624 vacuolar protein processing(GO:0006624)
0.0 1.2 GO:0010955 negative regulation of protein processing(GO:0010955) negative regulation of protein maturation(GO:1903318)
0.0 0.2 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 4.4 GO:0045580 regulation of T cell differentiation(GO:0045580)
0.0 0.1 GO:1902071 regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.0 0.2 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.7 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.2 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 3.9 GO:0060041 retina development in camera-type eye(GO:0060041)
0.0 2.0 GO:0007338 single fertilization(GO:0007338)
0.0 0.7 GO:0009649 entrainment of circadian clock(GO:0009649)
0.0 0.7 GO:0097320 membrane tubulation(GO:0097320)
0.0 0.9 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 1.4 GO:0034644 cellular response to UV(GO:0034644)
0.0 2.6 GO:0043010 camera-type eye development(GO:0043010)
0.0 2.4 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 2.4 GO:0016051 carbohydrate biosynthetic process(GO:0016051)
0.0 1.1 GO:0060349 bone morphogenesis(GO:0060349)
0.0 0.2 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.7 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.2 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 6.4 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
2.1 6.4 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
2.0 16.1 GO:0033269 internode region of axon(GO:0033269)
1.2 3.7 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.7 2.9 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.5 2.2 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.4 6.3 GO:0030061 mitochondrial crista(GO:0030061)
0.4 3.1 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.4 6.7 GO:0097470 ribbon synapse(GO:0097470)
0.3 3.5 GO:0005642 annulate lamellae(GO:0005642)
0.3 6.4 GO:0010369 chromocenter(GO:0010369)
0.3 2.2 GO:0042382 paraspeckles(GO:0042382)
0.3 15.8 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.2 4.1 GO:0005652 nuclear lamina(GO:0005652)
0.2 5.8 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.2 4.6 GO:0035253 ciliary rootlet(GO:0035253)
0.2 0.9 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.2 1.1 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.2 7.6 GO:0030673 axolemma(GO:0030673)
0.2 2.5 GO:0008385 IkappaB kinase complex(GO:0008385)
0.2 0.8 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1 0.6 GO:1990761 growth cone lamellipodium(GO:1990761)
0.1 2.2 GO:0031143 pseudopodium(GO:0031143)
0.1 1.9 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 1.5 GO:0005922 connexon complex(GO:0005922)
0.1 3.4 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 3.0 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 1.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 13.2 GO:0005923 bicellular tight junction(GO:0005923)
0.1 2.7 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.1 0.9 GO:0001739 sex chromatin(GO:0001739)
0.1 4.0 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 0.2 GO:0031417 NatC complex(GO:0031417)
0.1 1.2 GO:0005797 Golgi medial cisterna(GO:0005797)
0.1 0.5 GO:0097227 sperm annulus(GO:0097227)
0.1 0.7 GO:0031209 SCAR complex(GO:0031209)
0.1 2.4 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 2.7 GO:0031594 neuromuscular junction(GO:0031594)
0.0 1.3 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 4.1 GO:0016363 nuclear matrix(GO:0016363)
0.0 7.5 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 2.7 GO:0030016 myofibril(GO:0030016)
0.0 1.6 GO:0005811 lipid particle(GO:0005811)
0.0 0.1 GO:1990745 EARP complex(GO:1990745)
0.0 4.2 GO:0005802 trans-Golgi network(GO:0005802)
0.0 1.3 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.5 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.2 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.1 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
4.2 12.6 GO:0098770 FBXO family protein binding(GO:0098770)
1.6 6.4 GO:0050436 microfibril binding(GO:0050436)
1.3 5.2 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
1.3 7.6 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
1.1 6.4 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.9 6.6 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.9 3.5 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.8 6.7 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.8 2.5 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.8 2.4 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.8 2.3 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.7 6.7 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.7 13.0 GO:0051393 alpha-actinin binding(GO:0051393)
0.6 3.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.6 2.4 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.6 3.4 GO:0070644 vitamin D response element binding(GO:0070644)
0.5 1.9 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.5 2.7 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.4 5.8 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.4 2.2 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.4 8.2 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.4 2.5 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.4 19.2 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.3 3.5 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.3 1.6 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.3 0.9 GO:0003796 lysozyme activity(GO:0003796)
0.3 2.9 GO:0051011 microtubule minus-end binding(GO:0051011)
0.3 3.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.3 1.3 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.2 8.8 GO:0005112 Notch binding(GO:0005112)
0.2 1.8 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.2 4.2 GO:0017160 Ral GTPase binding(GO:0017160)
0.2 1.6 GO:0005212 structural constituent of eye lens(GO:0005212)
0.2 4.9 GO:0051183 vitamin transporter activity(GO:0051183)
0.1 1.9 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1 2.4 GO:0030553 cGMP binding(GO:0030553)
0.1 3.5 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.1 1.3 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.1 4.4 GO:0030332 cyclin binding(GO:0030332)
0.1 0.5 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.1 0.2 GO:0004568 chitinase activity(GO:0004568)
0.1 0.8 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 1.7 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 0.7 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.1 0.4 GO:0031432 titin binding(GO:0031432)
0.0 3.1 GO:0005179 hormone activity(GO:0005179)
0.0 1.1 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487) structural constituent of nuclear pore(GO:0017056)
0.0 4.6 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 5.9 GO:0017124 SH3 domain binding(GO:0017124)
0.0 1.0 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 1.0 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.8 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.3 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 2.7 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 1.8 GO:0017022 myosin binding(GO:0017022)
0.0 1.4 GO:0019842 vitamin binding(GO:0019842)
0.0 0.8 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 8.2 GO:0051020 GTPase binding(GO:0051020)
0.0 0.4 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 12.2 GO:0003682 chromatin binding(GO:0003682)
0.0 1.4 GO:0051087 chaperone binding(GO:0051087)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 1.2 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.9 GO:0016209 antioxidant activity(GO:0016209)
0.0 0.8 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.7 8.5 PID_CONE_PATHWAY Visual signal transduction: Cones
0.6 3.1 PID_AR_NONGENOMIC_PATHWAY Nongenotropic Androgen signaling
0.3 12.6 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.2 16.1 SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES Genes related to the insulin receptor pathway
0.2 3.5 PID_RANBP2_PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.2 8.6 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.2 1.4 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 3.4 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 0.8 SA_PTEN_PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 2.5 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.1 8.2 PID_NOTCH_PATHWAY Notch signaling pathway
0.1 3.6 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 3.2 PID_RETINOIC_ACID_PATHWAY Retinoic acid receptors-mediated signaling
0.1 1.8 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.1 5.1 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity
0.1 6.4 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.0 2.9 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.0 0.8 PID_HIV_NEF_PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.9 PID_FGF_PATHWAY FGF signaling pathway
0.0 2.5 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.4 NABA_PROTEOGLYCANS Genes encoding proteoglycans

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 REACTOME_HORMONE_LIGAND_BINDING_RECEPTORS Genes involved in Hormone ligand-binding receptors
0.8 8.8 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.7 16.1 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.5 2.4 REACTOME_OLFACTORY_SIGNALING_PATHWAY Genes involved in Olfactory Signaling Pathway
0.4 4.9 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.4 2.9 REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.4 7.1 REACTOME_INCRETIN_SYNTHESIS_SECRETION_AND_INACTIVATION Genes involved in Incretin Synthesis, Secretion, and Inactivation
0.3 2.7 REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS Genes involved in G alpha (q) signalling events
0.3 12.6 REACTOME_G1_PHASE Genes involved in G1 Phase
0.2 2.5 REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.2 6.7 REACTOME_PEROXISOMAL_LIPID_METABOLISM Genes involved in Peroxisomal lipid metabolism
0.2 9.8 REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.2 5.2 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.1 6.2 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.1 2.4 REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 3.1 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.1 1.1 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 1.6 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 3.1 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 2.2 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 3.5 REACTOME_POTASSIUM_CHANNELS Genes involved in Potassium Channels
0.0 2.7 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.3 REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 1.1 REACTOME_NEP_NS2_INTERACTS_WITH_THE_CELLULAR_EXPORT_MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.8 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.7 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.0 0.5 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.6 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 1.4 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 1.6 REACTOME_SIGNALING_BY_FGFR Genes involved in Signaling by FGFR
0.0 0.2 REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 1.2 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.2 REACTOME_STEROID_HORMONES Genes involved in Steroid hormones