Motif ID: Pitx2_Otx2

Z-value: 1.702

Transcription factors associated with Pitx2_Otx2:

Gene SymbolEntrez IDGene Name
Otx2 ENSMUSG00000021848.9 Otx2
Pitx2 ENSMUSG00000028023.10 Pitx2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Otx2mm10_v2_chr14_-_48667508_486676440.199.5e-02Click!
Pitx2mm10_v2_chr3_+_129199878_1291999130.085.1e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Pitx2_Otx2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_88898664 19.705 ENSMUST00000058011.6
Mcm2
minichromosome maintenance deficient 2 mitotin (S. cerevisiae)
chr4_-_117182623 13.234 ENSMUST00000065896.2
Kif2c
kinesin family member 2C
chr9_-_70421533 12.957 ENSMUST00000034742.6
Ccnb2
cyclin B2
chr4_+_80910646 12.774 ENSMUST00000055922.3
Lurap1l
leucine rich adaptor protein 1-like
chr8_+_127447669 11.931 ENSMUST00000159511.1
Pard3
par-3 (partitioning defective 3) homolog (C. elegans)
chr11_-_84068766 11.566 ENSMUST00000018792.5
Dusp14
dual specificity phosphatase 14
chr6_+_56017489 11.403 ENSMUST00000052827.4
Ppp1r17
protein phosphatase 1, regulatory subunit 17
chr11_-_84068554 11.030 ENSMUST00000164891.1
Dusp14
dual specificity phosphatase 14
chr11_-_106998483 11.005 ENSMUST00000124541.1
Kpna2
karyopherin (importin) alpha 2
chr6_+_34354119 10.444 ENSMUST00000038406.6
Akr1b8
aldo-keto reductase family 1, member B8
chr11_-_84069179 10.205 ENSMUST00000138208.1
Dusp14
dual specificity phosphatase 14
chr10_-_128180265 9.491 ENSMUST00000099139.1
Rbms2
RNA binding motif, single stranded interacting protein 2
chr7_+_16992708 9.108 ENSMUST00000094805.4
Ccdc8
coiled-coil domain containing 8
chr11_+_97029925 8.854 ENSMUST00000021249.4
Scrn2
secernin 2
chr14_-_47411666 8.539 ENSMUST00000111778.3
Dlgap5
discs, large (Drosophila) homolog-associated protein 5
chr18_+_34751803 8.043 ENSMUST00000181453.1
ENSMUST00000181641.1
2010110K18Rik

RIKEN cDNA 2010110K18 gene

chr7_-_99353104 7.563 ENSMUST00000169437.1
ENSMUST00000094154.4
Serpinh1

serine (or cysteine) peptidase inhibitor, clade H, member 1

chr7_-_75782080 7.546 ENSMUST00000181224.1
AU020206
expressed sequence AU020206
chr11_+_101448403 7.483 ENSMUST00000010502.6
Ifi35
interferon-induced protein 35
chr18_-_74207771 7.391 ENSMUST00000040188.8
ENSMUST00000177604.1
Ska1

spindle and kinetochore associated complex subunit 1

chrM_+_8600 7.212 ENSMUST00000082409.1
mt-Co3
mitochondrially encoded cytochrome c oxidase III
chr11_-_84068357 7.168 ENSMUST00000100705.4
Dusp14
dual specificity phosphatase 14
chr17_+_6430112 7.152 ENSMUST00000179569.1
Dynlt1b
dynein light chain Tctex-type 1B
chr18_+_34736359 7.138 ENSMUST00000105038.2
Gm3550
predicted gene 3550
chr7_-_118116128 7.030 ENSMUST00000128482.1
ENSMUST00000131840.1
Rps15a

ribosomal protein S15A

chr14_-_47418407 6.961 ENSMUST00000043296.3
Dlgap5
discs, large (Drosophila) homolog-associated protein 5
chr10_-_130280218 6.910 ENSMUST00000061571.3
Neurod4
neurogenic differentiation 4
chr4_-_130279205 6.825 ENSMUST00000120126.2
Serinc2
serine incorporator 2
chr14_+_55824795 6.816 ENSMUST00000024179.5
ENSMUST00000172271.1
Nfatc4

nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 4

chr3_-_36571952 6.794 ENSMUST00000029270.3
Ccna2
cyclin A2
chr1_+_92906959 6.726 ENSMUST00000060913.6
Dusp28
dual specificity phosphatase 28
chr9_-_114982739 6.469 ENSMUST00000053150.5
Gm9846
predicted gene 9846
chr11_-_120727226 6.463 ENSMUST00000106148.3
ENSMUST00000026144.4
Dcxr

dicarbonyl L-xylulose reductase

chr14_+_65806066 6.460 ENSMUST00000139644.1
Pbk
PDZ binding kinase
chr15_+_99006056 6.445 ENSMUST00000079818.3
Gm8973
predicted gene 8973
chr17_+_35861318 6.357 ENSMUST00000074259.8
ENSMUST00000174873.1
Nrm

nurim (nuclear envelope membrane protein)

chr2_+_164562579 6.282 ENSMUST00000017867.3
ENSMUST00000109344.2
ENSMUST00000109345.2
Wfdc2


WAP four-disulfide core domain 2


chr5_+_135725713 6.238 ENSMUST00000127096.1
Por
P450 (cytochrome) oxidoreductase
chr3_+_85915722 6.209 ENSMUST00000054148.7
Gm9790
predicted gene 9790
chr2_+_157737401 6.206 ENSMUST00000029178.6
Ctnnbl1
catenin, beta like 1
chr11_+_61956779 6.189 ENSMUST00000049836.7
Specc1
sperm antigen with calponin homology and coiled-coil domains 1
chr11_+_117199641 6.181 ENSMUST00000093907.4
Sept9
septin 9
chr11_+_101442298 6.128 ENSMUST00000077856.6
Rpl27
ribosomal protein L27
chr15_+_25752860 6.117 ENSMUST00000022882.5
ENSMUST00000135173.1
Myo10

myosin X

chr11_+_100574904 6.073 ENSMUST00000103120.4
Cnp
2',3'-cyclic nucleotide 3' phosphodiesterase
chr4_-_116994374 6.009 ENSMUST00000030446.8
Urod
uroporphyrinogen decarboxylase
chr9_-_100486788 5.953 ENSMUST00000098458.3
Il20rb
interleukin 20 receptor beta
chr4_+_154011731 5.870 ENSMUST00000169622.1
ENSMUST00000030894.8
Lrrc47

leucine rich repeat containing 47

chr19_+_6061176 5.869 ENSMUST00000162726.3
Znhit2
zinc finger, HIT domain containing 2
chr6_+_134929089 5.840 ENSMUST00000183867.1
ENSMUST00000184991.1
ENSMUST00000183905.1
RP23-45G16.5


RP23-45G16.5


chr1_-_175979114 5.792 ENSMUST00000104983.1
B020018G12Rik
RIKEN cDNA B020018G12 gene
chr15_-_102667749 5.755 ENSMUST00000075630.3
Atp5g2
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C2 (subunit 9)
chr4_-_116994354 5.739 ENSMUST00000130273.1
Urod
uroporphyrinogen decarboxylase
chr6_+_134929118 5.667 ENSMUST00000185152.1
ENSMUST00000184504.1
RP23-45G16.5

RP23-45G16.5

chr10_+_79996479 5.649 ENSMUST00000132517.1
Abca7
ATP-binding cassette, sub-family A (ABC1), member 7
chr11_-_116027961 5.643 ENSMUST00000106454.1
H3f3b
H3 histone, family 3B
chr8_+_85026833 5.382 ENSMUST00000047281.8
2310036O22Rik
RIKEN cDNA 2310036O22 gene
chr6_-_23248264 5.299 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr4_-_32923455 5.261 ENSMUST00000035719.4
ENSMUST00000084749.1
Ankrd6

ankyrin repeat domain 6

chr2_-_93957040 5.232 ENSMUST00000148314.2
Gm13889
predicted gene 13889
chr3_+_131112785 5.223 ENSMUST00000098611.3
Lef1
lymphoid enhancer binding factor 1
chr14_+_47472547 5.179 ENSMUST00000168833.1
ENSMUST00000163324.1
ENSMUST00000043112.7
Fbxo34


F-box protein 34


chr1_-_155232710 5.169 ENSMUST00000035914.3
BC034090
cDNA sequence BC034090
chr2_+_144594054 5.128 ENSMUST00000136628.1
Gm561
predicted gene 561
chr7_+_102225812 5.070 ENSMUST00000142873.1
Pgap2
post-GPI attachment to proteins 2
chr11_-_102925086 5.021 ENSMUST00000021311.9
Kif18b
kinesin family member 18B
chr2_+_174415804 5.002 ENSMUST00000109075.1
ENSMUST00000016397.6
Nelfcd

negative elongation factor complex member C/D, Th1l

chr17_-_70924958 4.977 ENSMUST00000180468.1
Gm26510
predicted gene, 26510
chr10_+_82954344 4.939 ENSMUST00000095396.3
Gm4799
predicted gene 4799
chr19_-_47919269 4.913 ENSMUST00000095998.5
Itprip
inositol 1,4,5-triphosphate receptor interacting protein
chr15_+_76879232 4.892 ENSMUST00000023179.5
Zfp7
zinc finger protein 7
chr5_-_4758216 4.887 ENSMUST00000054294.4
Fzd1
frizzled homolog 1 (Drosophila)
chr10_+_62947011 4.885 ENSMUST00000131422.1
Dna2
DNA replication helicase 2 homolog (yeast)
chr13_-_66852017 4.855 ENSMUST00000059329.6
Gm17449
predicted gene, 17449
chr17_+_24426676 4.824 ENSMUST00000024946.5
Eci1
enoyl-Coenzyme A delta isomerase 1
chr8_+_114133557 4.803 ENSMUST00000073521.5
ENSMUST00000066514.6
Nudt7

nudix (nucleoside diphosphate linked moiety X)-type motif 7

chr14_+_74735641 4.756 ENSMUST00000177283.1
Esd
esterase D/formylglutathione hydrolase
chr3_+_95111013 4.705 ENSMUST00000009102.8
Vps72
vacuolar protein sorting 72 (yeast)
chr7_+_16891755 4.693 ENSMUST00000078182.4
Gng8
guanine nucleotide binding protein (G protein), gamma 8
chr17_+_50698525 4.680 ENSMUST00000061681.7
Gm7334
predicted gene 7334
chr11_+_44617310 4.664 ENSMUST00000081265.5
ENSMUST00000101326.3
ENSMUST00000109268.1
Ebf1


early B cell factor 1


chr8_-_116993459 4.663 ENSMUST00000040484.5
Gcsh
glycine cleavage system protein H (aminomethyl carrier)
chr17_-_25727364 4.662 ENSMUST00000170070.1
ENSMUST00000048054.7
Chtf18

CTF18, chromosome transmission fidelity factor 18

chr3_+_55112080 4.636 ENSMUST00000044116.7
ENSMUST00000107971.2
ENSMUST00000118118.1
Spg20


spastic paraplegia 20, spartin (Troyer syndrome) homolog (human)


chr11_-_120796369 4.625 ENSMUST00000143139.1
ENSMUST00000129955.1
ENSMUST00000026151.4
ENSMUST00000167023.1
ENSMUST00000106133.1
ENSMUST00000106135.1
Dus1l





dihydrouridine synthase 1-like (S. cerevisiae)





chr9_+_114731177 4.610 ENSMUST00000035007.8
Cmtm6
CKLF-like MARVEL transmembrane domain containing 6
chr11_+_115403734 4.564 ENSMUST00000153983.1
ENSMUST00000106539.3
ENSMUST00000103036.4
Ict1


immature colon carcinoma transcript 1


chr7_-_118995211 4.540 ENSMUST00000008878.8
Gprc5b
G protein-coupled receptor, family C, group 5, member B
chr11_-_48826655 4.465 ENSMUST00000104959.1
Gm12184
predicted gene 12184
chr14_+_73173825 4.423 ENSMUST00000166875.1
Rcbtb2
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr9_+_66060169 4.402 ENSMUST00000034947.5
Ppib
peptidylprolyl isomerase B
chr11_-_73138245 4.381 ENSMUST00000052140.2
Gsg2
germ cell-specific gene 2
chr15_-_82244716 4.367 ENSMUST00000089155.4
ENSMUST00000089157.3
Cenpm

centromere protein M

chr16_-_46010212 4.348 ENSMUST00000130481.1
Plcxd2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr9_+_18427543 4.306 ENSMUST00000053326.9
Gm5612
predicted gene 5612
chr10_-_92722356 4.278 ENSMUST00000020163.6
Nedd1
neural precursor cell expressed, developmentally down-regulated gene 1
chr8_+_123062942 4.223 ENSMUST00000142541.1
ENSMUST00000125975.1
Spg7

spastic paraplegia 7 homolog (human)

chr15_+_102460076 4.221 ENSMUST00000164688.1
Prr13
proline rich 13
chr6_+_47920476 4.173 ENSMUST00000009411.8
Zfp212
Zinc finger protein 212
chr2_-_151973840 4.159 ENSMUST00000109865.1
ENSMUST00000109864.1
Fam110a

family with sequence similarity 110, member A

chr1_-_119648903 4.117 ENSMUST00000163147.1
ENSMUST00000052404.6
ENSMUST00000027632.7
Epb4.1l5


erythrocyte protein band 4.1-like 5


chr17_+_29090969 4.117 ENSMUST00000119901.1
Cdkn1a
cyclin-dependent kinase inhibitor 1A (P21)
chr10_+_128238034 4.087 ENSMUST00000105245.2
Timeless
timeless circadian clock 1
chr6_+_149582012 4.000 ENSMUST00000144085.2
Gm21814
predicted gene, 21814
chr2_-_180954676 3.966 ENSMUST00000148905.1
ENSMUST00000103053.3
ENSMUST00000108873.2
Nkain4


Na+/K+ transporting ATPase interacting 4


chr8_+_114133635 3.955 ENSMUST00000147605.1
ENSMUST00000134593.1
Nudt7

nudix (nucleoside diphosphate linked moiety X)-type motif 7

chr17_-_25880236 3.926 ENSMUST00000176696.1
ENSMUST00000095487.5
Wfikkn1

WAP, FS, Ig, KU, and NTR-containing protein 1

chr10_-_80320506 3.910 ENSMUST00000020341.8
2310011J03Rik
RIKEN cDNA 2310011J03 gene
chr10_+_20347788 3.908 ENSMUST00000169712.1
Mtfr2
mitochondrial fission regulator 2
chr16_-_4719078 3.894 ENSMUST00000120056.1
ENSMUST00000074970.7
Nmral1

NmrA-like family domain containing 1

chr10_+_128908907 3.860 ENSMUST00000105229.1
Cd63
CD63 antigen
chr17_-_6655939 3.858 ENSMUST00000179554.1
Dynlt1f
dynein light chain Tctex-type 1F
chr15_-_36308956 3.796 ENSMUST00000090170.4
Rpl7a-ps3
ribosomal protein L7A, pseudogene 3
chr6_-_124814288 3.788 ENSMUST00000172132.2
Tpi1
triosephosphate isomerase 1
chr4_-_140246751 3.767 ENSMUST00000039331.8
Igsf21
immunoglobulin superfamily, member 21
chr16_-_4719148 3.756 ENSMUST00000115851.3
Nmral1
NmrA-like family domain containing 1
chr17_-_35673738 3.755 ENSMUST00000001565.8
Gtf2h4
general transcription factor II H, polypeptide 4
chr10_+_80292453 3.727 ENSMUST00000068408.7
ENSMUST00000062674.6
Rps15

ribosomal protein S15

chr2_-_155582656 3.723 ENSMUST00000126322.1
Gss
glutathione synthetase
chr12_-_69159109 3.719 ENSMUST00000037023.8
Rps29
ribosomal protein S29
chr2_-_34913976 3.718 ENSMUST00000028232.3
Phf19
PHD finger protein 19
chr7_-_126792469 3.692 ENSMUST00000032936.6
Ppp4c
protein phosphatase 4, catalytic subunit
chr11_+_32205411 3.629 ENSMUST00000039601.3
ENSMUST00000149043.1
Snrnp25

small nuclear ribonucleoprotein 25 (U11/U12)

chr9_-_44344159 3.620 ENSMUST00000077353.7
Hmbs
hydroxymethylbilane synthase
chr6_-_72235559 3.584 ENSMUST00000042646.7
Atoh8
atonal homolog 8 (Drosophila)
chr19_+_33822908 3.567 ENSMUST00000042061.6
Gm5519
predicted pseudogene 5519
chr17_-_35121990 3.524 ENSMUST00000173915.1
ENSMUST00000172765.2
Csnk2b

casein kinase 2, beta polypeptide

chr11_-_58801944 3.522 ENSMUST00000094156.4
ENSMUST00000060581.3
Fam183b

family with sequence similarity 183, member B

chr15_+_76380492 3.454 ENSMUST00000096385.4
ENSMUST00000160728.1
ENSMUST00000162319.1
Mroh1


maestro heat-like repeat family member 1


chr11_+_116848901 3.423 ENSMUST00000143184.1
Mettl23
methyltransferase like 23
chr13_-_97747373 3.421 ENSMUST00000123535.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr5_-_121618865 3.418 ENSMUST00000041252.6
ENSMUST00000111776.1
Acad12

acyl-Coenzyme A dehydrogenase family, member 12

chr2_-_132247747 3.406 ENSMUST00000110163.1
ENSMUST00000180286.1
ENSMUST00000028816.2
Tmem230


transmembrane protein 230


chr5_+_3343893 3.398 ENSMUST00000165117.1
Cdk6
cyclin-dependent kinase 6
chr5_+_134932351 3.387 ENSMUST00000047196.7
ENSMUST00000111221.2
ENSMUST00000111219.1
ENSMUST00000068617.5
ENSMUST00000111218.1
ENSMUST00000136246.1
Wbscr27





Williams Beuren syndrome chromosome region 27 (human)





chr2_-_28466266 3.376 ENSMUST00000127683.1
ENSMUST00000086370.4
1700007K13Rik

RIKEN cDNA 1700007K13 gene

chr9_-_20898592 3.376 ENSMUST00000004206.8
Eif3g
eukaryotic translation initiation factor 3, subunit G
chr9_-_27155418 3.358 ENSMUST00000167074.1
ENSMUST00000034472.8
Jam3

junction adhesion molecule 3

chr3_-_63899437 3.351 ENSMUST00000159188.1
ENSMUST00000177143.1
Plch1

phospholipase C, eta 1

chr6_+_42350000 3.349 ENSMUST00000164375.1
Zyx
zyxin
chr11_-_106999482 3.345 ENSMUST00000018506.6
Kpna2
karyopherin (importin) alpha 2
chr3_-_90243073 3.338 ENSMUST00000107369.1
Creb3l4
cAMP responsive element binding protein 3-like 4
chr5_+_107900502 3.323 ENSMUST00000082223.6
Rpl5
ribosomal protein L5
chr5_-_93206428 3.317 ENSMUST00000144514.1
Ccni
cyclin I
chr7_-_140116395 3.316 ENSMUST00000026538.6
Echs1
enoyl Coenzyme A hydratase, short chain, 1, mitochondrial
chr5_+_137778849 3.299 ENSMUST00000126126.1
ENSMUST00000031739.4
Ppp1r35

protein phosphatase 1, regulatory subunit 35

chr11_-_40695203 3.253 ENSMUST00000101347.3
Mat2b
methionine adenosyltransferase II, beta
chr7_-_34812677 3.219 ENSMUST00000078686.6
Chst8
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
chr5_+_38260372 3.199 ENSMUST00000119047.1
Tmem128
transmembrane protein 128
chr4_-_138913915 3.197 ENSMUST00000097830.3
Otud3
OTU domain containing 3
chr7_-_143460989 3.190 ENSMUST00000167912.1
ENSMUST00000037287.6
Cdkn1c

cyclin-dependent kinase inhibitor 1C (P57)

chr6_+_42349826 3.189 ENSMUST00000070635.6
Zyx
zyxin
chr9_+_37208291 3.161 ENSMUST00000034632.8
Tmem218
transmembrane protein 218
chr19_+_10206033 3.159 ENSMUST00000166412.1
Tmem258
transmembrane protein 258
chr5_-_93206489 3.144 ENSMUST00000058550.8
Ccni
cyclin I
chr1_-_75219245 3.133 ENSMUST00000079464.6
Tuba4a
tubulin, alpha 4A
chr17_+_6601671 3.130 ENSMUST00000092966.4
Dynlt1c
dynein light chain Tctex-type 1C
chr7_+_27486910 3.129 ENSMUST00000008528.7
Sertad1
SERTA domain containing 1
chr15_-_5121172 3.126 ENSMUST00000090488.2
Gm10250
predicted pseudogene 10250
chr4_-_45489794 3.121 ENSMUST00000146236.1
Shb
src homology 2 domain-containing transforming protein B
chr7_-_30194150 3.120 ENSMUST00000126116.1
Capns1
calpain, small subunit 1
chr11_-_106999369 3.117 ENSMUST00000106768.1
ENSMUST00000144834.1
Kpna2

karyopherin (importin) alpha 2

chr15_+_80948484 3.114 ENSMUST00000023043.2
ENSMUST00000168756.1
ENSMUST00000164806.1
Adsl


adenylosuccinate lyase


chr12_-_28635914 3.088 ENSMUST00000074267.3
Rps7
ribosomal protein S7
chr10_-_127522428 3.084 ENSMUST00000026470.4
Shmt2
serine hydroxymethyltransferase 2 (mitochondrial)
chr6_+_83349446 3.081 ENSMUST00000136501.1
Bola3
bolA-like 3 (E. coli)
chr14_+_121878591 3.078 ENSMUST00000039803.5
Ubac2
ubiquitin associated domain containing 2
chr7_-_45128725 3.067 ENSMUST00000150350.1
Rpl13a
ribosomal protein L13A
chr16_-_38550173 3.059 ENSMUST00000036210.6
Poglut1
protein O-glucosyltransferase 1
chr8_-_71511762 3.058 ENSMUST00000048452.4
Plvap
plasmalemma vesicle associated protein
chr7_+_141131268 3.057 ENSMUST00000026568.8
Ptdss2
phosphatidylserine synthase 2
chr1_-_139377041 3.054 ENSMUST00000059825.5
Crb1
crumbs homolog 1 (Drosophila)
chr7_-_15946070 3.052 ENSMUST00000044158.8
Gltscr2
glioma tumor suppressor candidate region gene 2
chr2_-_118762607 3.039 ENSMUST00000059997.8
A430105I19Rik
RIKEN cDNA A430105I19 gene
chr17_+_35861343 3.034 ENSMUST00000172931.1
Nrm
nurim (nuclear envelope membrane protein)
chr4_-_15945359 2.989 ENSMUST00000029877.8
Decr1
2,4-dienoyl CoA reductase 1, mitochondrial
chr2_+_32757234 2.982 ENSMUST00000009707.7
ENSMUST00000177382.1
ENSMUST00000140999.1
Tor2a


torsin family 2, member A


chr7_-_118116171 2.959 ENSMUST00000131374.1
Rps15a
ribosomal protein S15A
chr10_+_18407658 2.954 ENSMUST00000037341.7
Nhsl1
NHS-like 1
chr9_-_78489141 2.949 ENSMUST00000154207.1
Eef1a1
eukaryotic translation elongation factor 1 alpha 1
chr5_-_44099220 2.944 ENSMUST00000165909.1
Prom1
prominin 1
chr13_-_51203065 2.943 ENSMUST00000091708.4
Hist1h2al
histone cluster 1, H2al
chr15_+_79670856 2.940 ENSMUST00000023062.3
Tomm22
translocase of outer mitochondrial membrane 22 homolog (yeast)
chr5_+_138116903 2.923 ENSMUST00000062350.8
ENSMUST00000110961.2
ENSMUST00000080732.3
ENSMUST00000110960.2
ENSMUST00000142185.1
ENSMUST00000136425.1
ENSMUST00000110959.1
Zscan21






zinc finger and SCAN domain containing 21






chr14_+_27039001 2.919 ENSMUST00000035336.3
Il17rd
interleukin 17 receptor D
chr6_-_71144338 2.913 ENSMUST00000074241.7
ENSMUST00000160918.1
Thnsl2

threonine synthase-like 2 (bacterial)

chr4_+_41762309 2.913 ENSMUST00000108042.2
Il11ra1
interleukin 11 receptor, alpha chain 1
chr6_-_88874045 2.906 ENSMUST00000038409.5
Podxl2
podocalyxin-like 2
chr7_+_45639964 2.901 ENSMUST00000148532.1
Mamstr
MEF2 activating motif and SAP domain containing transcriptional regulator
chr4_+_115000156 2.896 ENSMUST00000030490.6
Stil
Scl/Tal1 interrupting locus
chr5_-_127617372 2.892 ENSMUST00000031367.8
Slc15a4
solute carrier family 15, member 4
chr5_-_134456702 2.891 ENSMUST00000073161.5
ENSMUST00000171794.2
ENSMUST00000111245.2
ENSMUST00000100654.3
ENSMUST00000167084.2
ENSMUST00000100652.3
ENSMUST00000100650.3
ENSMUST00000074114.5
Gtf2ird1







general transcription factor II I repeat domain-containing 1







chr7_-_19573343 2.889 ENSMUST00000051364.3
Gemin7
gem (nuclear organelle) associated protein 7
chr4_-_117156144 2.876 ENSMUST00000102696.4
Rps8
ribosomal protein S8
chr6_-_85933379 2.869 ENSMUST00000162660.1
Nat8b
N-acetyltransferase 8B
chr18_-_20682963 2.868 ENSMUST00000165229.2
Gm10269
predicted gene 10269
chr4_+_62559825 2.864 ENSMUST00000065870.7
Rgs3
regulator of G-protein signaling 3
chr5_-_123012874 2.864 ENSMUST00000172729.1
Kdm2b
lysine (K)-specific demethylase 2B
chr9_+_107576915 2.842 ENSMUST00000112387.2
ENSMUST00000123005.1
ENSMUST00000010195.7
ENSMUST00000144392.1
Hyal1



hyaluronoglucosaminidase 1



chr6_-_114969986 2.840 ENSMUST00000139640.1
Vgll4
vestigial like 4 (Drosophila)

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.5 10.4 GO:0016095 polyprenol catabolic process(GO:0016095) terpenoid catabolic process(GO:0016115) primary alcohol catabolic process(GO:0034310)
3.0 8.9 GO:0042732 D-xylose metabolic process(GO:0042732)
2.9 8.8 GO:0015938 coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034) acetyl-CoA catabolic process(GO:0046356)
2.6 13.2 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
2.3 13.9 GO:0046502 uroporphyrinogen III metabolic process(GO:0046502)
2.3 6.8 GO:2000297 negative regulation of synapse maturation(GO:2000297)
2.0 11.9 GO:0003383 apical constriction(GO:0003383)
2.0 6.0 GO:0002865 immune response-inhibiting signal transduction(GO:0002765) negative regulation of acute inflammatory response to antigenic stimulus(GO:0002865)
2.0 19.7 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
1.7 5.2 GO:0032696 negative regulation of interleukin-13 production(GO:0032696) trachea submucosa development(GO:0061152) trachea gland development(GO:0061153) odontoblast differentiation(GO:0071895) regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
1.7 5.2 GO:1902071 regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
1.6 4.9 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
1.6 4.8 GO:0050713 negative regulation of interleukin-1 beta secretion(GO:0050713)
1.6 4.8 GO:0046294 formaldehyde catabolic process(GO:0046294)
1.6 6.2 GO:0046210 nitrate catabolic process(GO:0043602) nitric oxide catabolic process(GO:0046210) cellular organohalogen metabolic process(GO:0090345) cellular organofluorine metabolic process(GO:0090346)
1.6 4.7 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
1.6 4.7 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
1.5 4.6 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
1.5 5.8 GO:1902990 mitotic telomere maintenance via semi-conservative replication(GO:1902990)
1.4 5.6 GO:1902340 telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340)
1.4 4.1 GO:1904975 response to bleomycin(GO:1904975) cellular response to bleomycin(GO:1904976)
1.3 3.8 GO:0019405 alditol catabolic process(GO:0019405)
1.3 2.5 GO:0008300 isoprenoid catabolic process(GO:0008300)
1.1 3.4 GO:0016237 lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) suppression by virus of host autophagy(GO:0039521) negative regulation of sphingolipid biosynthesis involved in cellular sphingolipid homeostasis(GO:0090157)
1.1 5.6 GO:1902995 apolipoprotein A-I-mediated signaling pathway(GO:0038027) regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995)
1.1 39.1 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
1.1 3.3 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630) positive regulation of aminoacyl-tRNA ligase activity(GO:1903632) regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
1.1 5.4 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
1.1 3.3 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
1.1 7.6 GO:0003433 chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
1.1 3.2 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
1.0 3.1 GO:0050787 glycolate metabolic process(GO:0009441) enzyme active site formation via L-cysteine sulfinic acid(GO:0018323) primary alcohol biosynthetic process(GO:0034309) cellular response to glyoxal(GO:0036471) glycolate biosynthetic process(GO:0046295) detoxification of mercury ion(GO:0050787) negative regulation of TRAIL-activated apoptotic signaling pathway(GO:1903122) regulation of pyrroline-5-carboxylate reductase activity(GO:1903167) positive regulation of pyrroline-5-carboxylate reductase activity(GO:1903168) regulation of tyrosine 3-monooxygenase activity(GO:1903176) positive regulation of tyrosine 3-monooxygenase activity(GO:1903178) L-dopa metabolic process(GO:1903184) L-dopa biosynthetic process(GO:1903185) glyoxal metabolic process(GO:1903189) regulation of L-dopa biosynthetic process(GO:1903195) positive regulation of L-dopa biosynthetic process(GO:1903197) regulation of L-dopa decarboxylase activity(GO:1903198) positive regulation of L-dopa decarboxylase activity(GO:1903200) positive regulation of cellular amino acid biosynthetic process(GO:2000284)
1.0 5.1 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
1.0 2.9 GO:0072139 glomerular parietal epithelial cell differentiation(GO:0072139)
1.0 6.8 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
1.0 2.9 GO:0006566 threonine metabolic process(GO:0006566)
1.0 2.9 GO:1904046 seryl-tRNA aminoacylation(GO:0006434) negative regulation of vascular endothelial growth factor production(GO:1904046)
0.9 5.7 GO:0048318 axial mesoderm development(GO:0048318)
0.9 2.8 GO:0036118 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.9 4.7 GO:0019236 response to pheromone(GO:0019236)
0.9 2.7 GO:0006545 glycine biosynthetic process(GO:0006545)
0.9 2.7 GO:0046462 monoacylglycerol metabolic process(GO:0046462)
0.9 2.7 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.9 2.7 GO:0036233 glycine import(GO:0036233)
0.9 5.3 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.9 3.5 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.9 1.7 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.8 2.5 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.8 7.4 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.8 2.5 GO:0006272 leading strand elongation(GO:0006272) DNA replication proofreading(GO:0045004)
0.8 4.1 GO:0033499 galactose catabolic process via UDP-galactose(GO:0033499)
0.8 5.7 GO:1904627 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.8 1.6 GO:1903519 apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.8 3.9 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.8 18.0 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.8 3.9 GO:2000680 regulation of rubidium ion transport(GO:2000680)
0.8 3.1 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.8 4.5 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.7 2.2 GO:0006868 glutamine transport(GO:0006868)
0.7 3.7 GO:0061085 regulation of histone H3-K27 methylation(GO:0061085) positive regulation of histone H3-K27 methylation(GO:0061087)
0.7 8.1 GO:0018065 protein-cofactor linkage(GO:0018065)
0.7 2.2 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.7 2.2 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.7 2.1 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)
0.7 2.0 GO:2000409 positive regulation of T cell extravasation(GO:2000409)
0.7 3.4 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.7 2.7 GO:0045950 negative regulation of mitotic recombination(GO:0045950)
0.6 2.4 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.6 2.3 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.6 2.3 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.6 5.8 GO:1904667 negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.6 2.3 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.6 2.9 GO:0015817 histidine transport(GO:0015817)
0.6 2.9 GO:0021993 initiation of neural tube closure(GO:0021993)
0.6 1.1 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.6 5.1 GO:0033504 floor plate development(GO:0033504)
0.6 1.7 GO:0006667 sphinganine metabolic process(GO:0006667)
0.6 2.2 GO:0006203 dGTP catabolic process(GO:0006203) dATP catabolic process(GO:0046061)
0.6 4.4 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.6 2.2 GO:0006788 heme oxidation(GO:0006788)
0.5 3.7 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.5 6.9 GO:0035881 amacrine cell differentiation(GO:0035881)
0.5 1.6 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.5 3.6 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.5 2.6 GO:0019244 lactate biosynthetic process from pyruvate(GO:0019244)
0.5 1.5 GO:0001978 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978)
0.5 2.5 GO:0019614 catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.5 5.0 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.5 1.5 GO:0036166 phenotypic switching(GO:0036166)
0.5 1.5 GO:1904953 Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904953)
0.5 1.9 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726)
0.5 1.4 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.5 1.4 GO:1901856 negative regulation of cellular respiration(GO:1901856)
0.5 1.4 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.5 2.8 GO:2000210 positive regulation of anoikis(GO:2000210)
0.5 1.4 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.5 2.3 GO:0007256 activation of JNKK activity(GO:0007256)
0.4 5.3 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.4 0.9 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.4 3.5 GO:0071493 cellular response to UV-B(GO:0071493)
0.4 2.2 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.4 1.3 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.4 3.4 GO:0002051 osteoblast fate commitment(GO:0002051)
0.4 2.1 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.4 2.5 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.4 2.5 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.4 6.0 GO:0006085 acetyl-CoA biosynthetic process(GO:0006085)
0.4 1.2 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.4 3.2 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.4 2.8 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.4 1.6 GO:0030043 actin filament fragmentation(GO:0030043)
0.4 2.3 GO:0036006 response to macrophage colony-stimulating factor(GO:0036005) cellular response to macrophage colony-stimulating factor stimulus(GO:0036006)
0.4 1.9 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.4 1.9 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.4 1.5 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.4 3.4 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.4 3.0 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.4 2.6 GO:0051024 positive regulation of immunoglobulin secretion(GO:0051024)
0.4 3.0 GO:0097475 motor neuron migration(GO:0097475)
0.4 1.8 GO:0006741 NADP biosynthetic process(GO:0006741)
0.4 1.4 GO:0006624 vacuolar protein processing(GO:0006624)
0.4 0.7 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.4 2.5 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.4 2.1 GO:0086028 bundle of His cell to Purkinje myocyte signaling(GO:0086028) bundle of His cell action potential(GO:0086043)
0.4 2.1 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.3 3.1 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.3 9.3 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.3 1.7 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.3 3.4 GO:0071763 nuclear membrane organization(GO:0071763)
0.3 0.7 GO:0003274 endocardial cushion fusion(GO:0003274)
0.3 1.3 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.3 1.3 GO:1903772 regulation of viral budding via host ESCRT complex(GO:1903772)
0.3 1.0 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.3 2.0 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.3 1.3 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.3 2.5 GO:0008343 adult feeding behavior(GO:0008343)
0.3 1.0 GO:0021972 corticospinal neuron axon guidance through spinal cord(GO:0021972) positive regulation of negative chemotaxis(GO:0050924) induction of negative chemotaxis(GO:0050929) negative regulation of mononuclear cell migration(GO:0071676) regulation of retinal ganglion cell axon guidance(GO:0090259) negative regulation of retinal ganglion cell axon guidance(GO:0090260)
0.3 0.6 GO:0090202 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.3 0.9 GO:1990523 bone regeneration(GO:1990523)
0.3 6.5 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.3 3.1 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.3 2.2 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.3 2.8 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.3 3.1 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.3 1.2 GO:0030576 Cajal body organization(GO:0030576)
0.3 3.3 GO:0006228 UTP biosynthetic process(GO:0006228)
0.3 1.2 GO:0033087 negative regulation of immature T cell proliferation(GO:0033087)
0.3 3.5 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.3 3.8 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.3 7.5 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.3 7.1 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.3 2.3 GO:1901162 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.3 0.3 GO:0046544 development of secondary male sexual characteristics(GO:0046544)
0.3 2.5 GO:0060338 regulation of type I interferon-mediated signaling pathway(GO:0060338)
0.3 1.4 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.3 1.7 GO:0060330 regulation of response to interferon-gamma(GO:0060330)
0.3 0.8 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
0.3 9.7 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.3 1.3 GO:0048539 bone marrow development(GO:0048539)
0.3 1.3 GO:0019321 pentose metabolic process(GO:0019321)
0.3 1.6 GO:0021539 subthalamus development(GO:0021539)
0.3 1.1 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.3 1.1 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.3 2.6 GO:0006271 DNA strand elongation involved in DNA replication(GO:0006271)
0.3 3.6 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.3 3.6 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.3 2.0 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.3 0.8 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.3 2.0 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.3 2.5 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.2 0.7 GO:1904719 excitatory chemical synaptic transmission(GO:0098976) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.2 1.0 GO:0080184 response to stilbenoid(GO:0035634) response to phenylpropanoid(GO:0080184)
0.2 1.0 GO:0006166 purine ribonucleoside salvage(GO:0006166)
0.2 1.0 GO:0015822 ornithine transport(GO:0015822)
0.2 2.2 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.2 1.9 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.2 0.9 GO:0015705 iodide transport(GO:0015705)
0.2 1.9 GO:0071494 cellular response to UV-C(GO:0071494)
0.2 1.2 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.2 5.2 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.2 1.6 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.2 1.4 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.2 11.8 GO:0009060 aerobic respiration(GO:0009060)
0.2 1.4 GO:0032229 negative regulation of synaptic transmission, GABAergic(GO:0032229)
0.2 0.9 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.2 1.6 GO:0042148 strand invasion(GO:0042148)
0.2 0.9 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.2 1.6 GO:0015675 nickel cation transport(GO:0015675)
0.2 3.4 GO:0055070 copper ion homeostasis(GO:0055070)
0.2 2.5 GO:0032988 ribonucleoprotein complex disassembly(GO:0032988)
0.2 2.4 GO:0070836 caveola assembly(GO:0070836)
0.2 0.9 GO:0018201 peptidyl-glycine modification(GO:0018201)
0.2 1.3 GO:0035878 nail development(GO:0035878)
0.2 2.2 GO:0006825 copper ion transport(GO:0006825)
0.2 2.2 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.2 3.2 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.2 6.3 GO:0006739 NADP metabolic process(GO:0006739)
0.2 1.9 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.2 1.2 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.2 0.8 GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.2 1.0 GO:0018002 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.2 1.4 GO:0036506 maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.2 2.7 GO:0043249 erythrocyte maturation(GO:0043249)
0.2 8.9 GO:0043029 T cell homeostasis(GO:0043029)
0.2 1.8 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.2 0.8 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.2 2.0 GO:0030322 stabilization of membrane potential(GO:0030322)
0.2 3.5 GO:0006625 protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.2 1.8 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.2 0.6 GO:0090669 telomerase RNA stabilization(GO:0090669)
0.2 2.3 GO:0051601 exocyst localization(GO:0051601)
0.2 1.5 GO:1990000 amyloid fibril formation(GO:1990000)
0.2 3.4 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.2 0.6 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.2 0.8 GO:0002339 B cell selection(GO:0002339)
0.2 2.8 GO:0042407 cristae formation(GO:0042407)
0.2 2.8 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.2 1.3 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.2 0.9 GO:0015960 diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966)
0.2 6.8 GO:0016572 histone phosphorylation(GO:0016572)
0.2 1.3 GO:0045945 positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.2 1.6 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.2 2.9 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.2 0.5 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.2 7.1 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.2 10.3 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.2 0.5 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.2 2.8 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.2 0.7 GO:0090343 positive regulation of cell aging(GO:0090343) positive regulation of cellular senescence(GO:2000774)
0.2 4.0 GO:0016180 snRNA processing(GO:0016180)
0.2 3.1 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.2 2.7 GO:0042438 melanin biosynthetic process(GO:0042438)
0.2 0.5 GO:0070488 regulation of integrin biosynthetic process(GO:0045113) neutrophil aggregation(GO:0070488)
0.2 1.0 GO:0030223 neutrophil differentiation(GO:0030223)
0.2 1.2 GO:0031953 negative regulation of protein autophosphorylation(GO:0031953)
0.2 1.0 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
0.2 0.3 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.2 1.5 GO:0070874 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.2 1.1 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291)
0.2 3.2 GO:0016486 peptide hormone processing(GO:0016486)
0.2 1.6 GO:0039702 viral budding via host ESCRT complex(GO:0039702)
0.2 17.2 GO:0010921 regulation of phosphatase activity(GO:0010921)
0.2 0.8 GO:0071294 cellular response to zinc ion(GO:0071294)
0.1 1.8 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.1 0.4 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.1 0.9 GO:0044331 cell-cell adhesion mediated by cadherin(GO:0044331)
0.1 1.9 GO:0043248 proteasome assembly(GO:0043248)
0.1 1.0 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.1 4.3 GO:0071539 protein localization to centrosome(GO:0071539)
0.1 1.9 GO:0071353 response to interleukin-4(GO:0070670) cellular response to interleukin-4(GO:0071353)
0.1 1.3 GO:0016926 protein desumoylation(GO:0016926)
0.1 1.2 GO:0000963 mitochondrial RNA processing(GO:0000963)
0.1 1.2 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.1 5.8 GO:0000132 establishment of mitotic spindle orientation(GO:0000132)
0.1 4.0 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.1 1.7 GO:0001522 pseudouridine synthesis(GO:0001522)
0.1 0.3 GO:1904058 positive regulation of sensory perception of pain(GO:1904058)
0.1 0.8 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.1 2.9 GO:0001779 natural killer cell differentiation(GO:0001779)
0.1 3.4 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.1 2.2 GO:0009261 purine ribonucleotide catabolic process(GO:0009154) ribonucleotide catabolic process(GO:0009261)
0.1 8.6 GO:1901799 negative regulation of proteasomal protein catabolic process(GO:1901799)
0.1 1.4 GO:0036035 osteoclast development(GO:0036035)
0.1 4.5 GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.1 1.2 GO:1901838 regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901836) positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.1 0.8 GO:0060325 head morphogenesis(GO:0060323) face morphogenesis(GO:0060325)
0.1 3.3 GO:1903427 negative regulation of reactive oxygen species biosynthetic process(GO:1903427)
0.1 0.4 GO:2000645 negative regulation of receptor catabolic process(GO:2000645)
0.1 2.1 GO:0000338 protein deneddylation(GO:0000338)
0.1 2.6 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.1 0.5 GO:0042373 vitamin K metabolic process(GO:0042373)
0.1 2.2 GO:0006783 heme biosynthetic process(GO:0006783)
0.1 2.0 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.1 0.9 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.1 0.6 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 2.0 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.1 2.1 GO:0045760 positive regulation of action potential(GO:0045760)
0.1 0.9 GO:0042989 sequestering of actin monomers(GO:0042989)
0.1 1.0 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.1 4.5 GO:0008089 anterograde axonal transport(GO:0008089)
0.1 1.3 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.1 1.2 GO:0036037 CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 1.7 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.1 0.2 GO:1902969 mitotic DNA replication(GO:1902969)
0.1 1.3 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 1.3 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.1 0.6 GO:0090383 phagosome acidification(GO:0090383)
0.1 0.8 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.1 1.6 GO:0070527 platelet aggregation(GO:0070527)
0.1 2.1 GO:0044783 mitotic G1 DNA damage checkpoint(GO:0031571) G1 DNA damage checkpoint(GO:0044783)
0.1 1.4 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.1 1.2 GO:0021796 cerebral cortex regionalization(GO:0021796) embryonic brain development(GO:1990403)
0.1 2.6 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.1 0.6 GO:0018344 protein geranylgeranylation(GO:0018344)
0.1 11.7 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.1 0.2 GO:1901355 response to rapamycin(GO:1901355)
0.1 0.9 GO:0035646 endosome to melanosome transport(GO:0035646) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757)
0.1 0.6 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.1 1.8 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.1 0.8 GO:0042136 neurotransmitter biosynthetic process(GO:0042136)
0.1 1.1 GO:0006337 nucleosome disassembly(GO:0006337)
0.1 0.6 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.1 2.3 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.1 9.7 GO:0031109 microtubule polymerization or depolymerization(GO:0031109)
0.1 1.0 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.1 0.3 GO:0061303 cardiac ventricle formation(GO:0003211) soft palate development(GO:0060023) cornea development in camera-type eye(GO:0061303)
0.1 1.6 GO:0071806 intracellular protein transmembrane transport(GO:0065002) protein transmembrane transport(GO:0071806)
0.1 0.5 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.1 7.1 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.1 1.2 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.1 1.6 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.1 0.4 GO:0021940 positive regulation of cerebellar granule cell precursor proliferation(GO:0021940)
0.1 0.7 GO:0006144 purine nucleobase metabolic process(GO:0006144)
0.1 2.3 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.1 2.5 GO:0015909 long-chain fatty acid transport(GO:0015909)
0.1 4.2 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.1 1.0 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.1 1.0 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.1 1.4 GO:0003334 keratinocyte development(GO:0003334)
0.1 0.9 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.1 4.3 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.1 2.4 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.1 3.0 GO:0009214 cyclic nucleotide catabolic process(GO:0009214)
0.1 0.7 GO:0035413 positive regulation of catenin import into nucleus(GO:0035413)
0.1 1.0 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.1 0.3 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.1 3.8 GO:0035019 somatic stem cell population maintenance(GO:0035019)
0.1 0.8 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 3.5 GO:0045454 cell redox homeostasis(GO:0045454)
0.1 0.8 GO:0033108 mitochondrial respiratory chain complex assembly(GO:0033108)
0.1 0.5 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.1 1.8 GO:0001702 gastrulation with mouth forming second(GO:0001702)
0.1 0.9 GO:0007398 ectoderm development(GO:0007398)
0.1 0.6 GO:0021554 optic nerve development(GO:0021554)
0.1 0.7 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.1 0.6 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 1.4 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.1 0.3 GO:0051593 response to folic acid(GO:0051593)
0.1 0.4 GO:0030903 notochord development(GO:0030903)
0.1 1.5 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.1 1.0 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1 0.3 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.1 1.0 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.1 0.4 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.1 1.0 GO:0000266 mitochondrial fission(GO:0000266)
0.1 0.2 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.1 0.5 GO:0070475 rRNA base methylation(GO:0070475)
0.1 0.6 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.1 2.9 GO:0016925 protein sumoylation(GO:0016925)
0.1 0.6 GO:0006270 DNA replication initiation(GO:0006270)
0.1 2.0 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.1 0.2 GO:0050975 sensory perception of touch(GO:0050975)
0.1 0.3 GO:0033227 dsRNA transport(GO:0033227)
0.1 0.2 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.1 0.5 GO:0046548 retinal rod cell development(GO:0046548)
0.1 2.1 GO:0006749 glutathione metabolic process(GO:0006749)
0.1 0.2 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.1 2.9 GO:0032543 mitochondrial translation(GO:0032543)
0.1 1.0 GO:0030262 apoptotic nuclear changes(GO:0030262)
0.1 1.5 GO:1901796 regulation of signal transduction by p53 class mediator(GO:1901796)
0.1 1.1 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.1 1.9 GO:0046579 positive regulation of Ras protein signal transduction(GO:0046579)
0.1 0.5 GO:0001675 acrosome assembly(GO:0001675)
0.1 0.3 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0 0.1 GO:0070103 regulation of interleukin-6-mediated signaling pathway(GO:0070103) negative regulation of interleukin-6-mediated signaling pathway(GO:0070104)
0.0 0.4 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.6 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.8 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 2.5 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 1.2 GO:0014003 oligodendrocyte development(GO:0014003)
0.0 0.5 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.0 0.4 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0 0.9 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.4 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 1.5 GO:0051881 regulation of mitochondrial membrane potential(GO:0051881)
0.0 2.5 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.9 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.0 0.3 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.0 1.8 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0 1.0 GO:0045026 plasma membrane fusion(GO:0045026)
0.0 1.1 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.5 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.5 GO:0045070 positive regulation of viral genome replication(GO:0045070)
0.0 0.7 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.0 1.1 GO:0007566 embryo implantation(GO:0007566)
0.0 0.2 GO:0006265 DNA topological change(GO:0006265) UV protection(GO:0009650)
0.0 0.1 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.1 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.0 0.2 GO:0010820 positive regulation of T cell chemotaxis(GO:0010820)
0.0 1.2 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.1 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.0 0.1 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.0 0.2 GO:0006449 regulation of translational termination(GO:0006449)
0.0 1.9 GO:0000082 G1/S transition of mitotic cell cycle(GO:0000082)
0.0 0.1 GO:0030202 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.1 GO:0045056 transcytosis(GO:0045056)
0.0 2.1 GO:0051028 mRNA transport(GO:0051028)
0.0 0.2 GO:2000096 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095) positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.6 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.2 GO:1902017 regulation of cilium assembly(GO:1902017)
0.0 0.5 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 2.1 GO:0016331 morphogenesis of embryonic epithelium(GO:0016331)
0.0 0.8 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.3 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.0 GO:0030473 nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration(GO:0021817) nuclear migration along microtubule(GO:0030473)
0.0 0.1 GO:0044375 regulation of peroxisome size(GO:0044375)
0.0 0.9 GO:0000187 activation of MAPK activity(GO:0000187)
0.0 0.6 GO:0001942 hair follicle development(GO:0001942) skin epidermis development(GO:0098773)
0.0 0.2 GO:0051642 centrosome localization(GO:0051642)
0.0 0.3 GO:0018345 protein palmitoylation(GO:0018345)
0.0 1.0 GO:0048489 synaptic vesicle transport(GO:0048489) establishment of synaptic vesicle localization(GO:0097480)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 19.4 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
1.8 5.3 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
1.7 5.2 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
1.6 6.3 GO:0032021 NELF complex(GO:0032021)
1.5 9.1 GO:1990393 3M complex(GO:1990393)
1.5 11.9 GO:0033269 internode region of axon(GO:0033269)
1.4 4.1 GO:0070557 PCNA-p21 complex(GO:0070557)
1.4 9.5 GO:0001940 male pronucleus(GO:0001940)
1.2 3.5 GO:0000814 ESCRT II complex(GO:0000814)
1.2 6.9 GO:0097504 Gemini of coiled bodies(GO:0097504)
1.1 3.3 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
1.1 4.3 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
1.1 4.2 GO:0005745 m-AAA complex(GO:0005745)
1.0 2.9 GO:0071914 prominosome(GO:0071914)
1.0 2.9 GO:1990047 spindle matrix(GO:1990047)
1.0 3.9 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
1.0 2.9 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.9 3.8 GO:0000438 core TFIIH complex portion of holo TFIIH complex(GO:0000438)
0.9 2.8 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.9 3.4 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.8 5.0 GO:0000235 astral microtubule(GO:0000235)
0.8 7.4 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.8 15.5 GO:0031616 spindle pole centrosome(GO:0031616)
0.8 4.8 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.8 3.1 GO:0070552 BRISC complex(GO:0070552)
0.8 6.1 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.7 7.1 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.7 9.9 GO:0005652 nuclear lamina(GO:0005652)
0.7 8.5 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.6 1.9 GO:0000801 central element(GO:0000801)
0.6 2.4 GO:0030891 VCB complex(GO:0030891)
0.6 43.3 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.6 7.4 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.6 8.5 GO:0031105 septin complex(GO:0031105)
0.6 2.3 GO:0043005 neuron projection(GO:0043005)
0.6 3.4 GO:0033010 paranodal junction(GO:0033010)
0.6 28.9 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.6 5.0 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.5 19.8 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.5 3.5 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.5 1.5 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.5 3.0 GO:0005796 Golgi lumen(GO:0005796)
0.5 1.5 GO:0000811 GINS complex(GO:0000811)
0.5 2.5 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.5 5.2 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.5 4.7 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.5 1.4 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.5 1.9 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.5 6.4 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.5 6.3 GO:0000974 Prp19 complex(GO:0000974)
0.4 0.9 GO:0001520 outer dense fiber(GO:0001520)
0.4 5.3 GO:0042575 DNA polymerase complex(GO:0042575)
0.4 1.7 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.4 1.6 GO:0014802 terminal cisterna(GO:0014802)
0.4 3.2 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.4 12.7 GO:0035371 microtubule plus-end(GO:0035371)
0.4 4.1 GO:0005688 U6 snRNP(GO:0005688)
0.4 2.1 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.3 4.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.3 1.3 GO:0035339 SPOTS complex(GO:0035339)
0.3 3.9 GO:0044666 MLL3/4 complex(GO:0044666)
0.3 0.6 GO:0042555 MCM complex(GO:0042555)
0.3 1.6 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.3 1.3 GO:0097447 dendritic tree(GO:0097447)
0.3 2.8 GO:0061617 MICOS complex(GO:0061617)
0.3 2.8 GO:0045252 dihydrolipoyl dehydrogenase complex(GO:0045240) oxoglutarate dehydrogenase complex(GO:0045252)
0.3 2.1 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.3 1.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.3 2.3 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.3 2.7 GO:0000243 commitment complex(GO:0000243)
0.3 12.8 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.3 1.8 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.3 0.5 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.3 2.6 GO:0005682 U5 snRNP(GO:0005682)
0.3 2.5 GO:0070545 PeBoW complex(GO:0070545)
0.2 1.2 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.2 1.2 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.2 3.8 GO:0032039 integrator complex(GO:0032039)
0.2 1.4 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.2 0.9 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.2 0.9 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.2 5.6 GO:0001891 phagocytic cup(GO:0001891)
0.2 2.4 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.2 1.5 GO:0090543 Flemming body(GO:0090543)
0.2 1.1 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.2 17.5 GO:0005643 nuclear pore(GO:0005643)
0.2 3.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.2 1.3 GO:0070847 core mediator complex(GO:0070847)
0.2 2.1 GO:0000815 ESCRT III complex(GO:0000815)
0.2 1.4 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.2 3.7 GO:0000145 exocyst(GO:0000145)
0.2 3.6 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.2 6.5 GO:1990204 oxidoreductase complex(GO:1990204)
0.2 2.5 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.2 1.1 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.2 8.2 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.2 1.5 GO:1990909 Wnt signalosome(GO:1990909)
0.2 2.0 GO:0000812 Swr1 complex(GO:0000812)
0.2 1.7 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.2 1.4 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.2 5.6 GO:0000788 nuclear nucleosome(GO:0000788)
0.2 1.5 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.2 1.8 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.2 1.5 GO:0005798 Golgi-associated vesicle(GO:0005798)
0.2 0.3 GO:0098576 lumenal side of membrane(GO:0098576)
0.2 4.3 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.2 0.5 GO:0001533 cornified envelope(GO:0001533)
0.2 0.6 GO:0071797 LUBAC complex(GO:0071797)
0.2 3.1 GO:0071011 precatalytic spliceosome(GO:0071011)
0.2 0.8 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.2 1.6 GO:0046930 pore complex(GO:0046930) Bcl-2 family protein complex(GO:0097136)
0.2 8.2 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 1.3 GO:0000813 ESCRT I complex(GO:0000813)
0.1 0.6 GO:0045335 phagocytic vesicle(GO:0045335)
0.1 0.4 GO:0005588 collagen type V trimer(GO:0005588)
0.1 1.9 GO:0031209 SCAR complex(GO:0031209)
0.1 3.6 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1 2.2 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.1 1.5 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 1.8 GO:0031011 Ino80 complex(GO:0031011)
0.1 0.5 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.1 5.3 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 6.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 0.3 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.1 1.3 GO:0016272 prefoldin complex(GO:0016272)
0.1 1.1 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 4.4 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 1.8 GO:0031528 microvillus membrane(GO:0031528)
0.1 0.7 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 6.1 GO:0016459 myosin complex(GO:0016459)
0.1 0.6 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.1 6.9 GO:0005925 focal adhesion(GO:0005925)
0.1 6.2 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1 0.9 GO:0031941 filamentous actin(GO:0031941)
0.1 2.1 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.1 0.7 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.1 7.2 GO:0005811 lipid particle(GO:0005811)
0.1 5.8 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 19.4 GO:0005759 mitochondrial matrix(GO:0005759)
0.1 1.4 GO:0030061 mitochondrial crista(GO:0030061)
0.1 3.4 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.1 0.8 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.1 1.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 29.3 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.1 2.1 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 0.3 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.1 0.5 GO:0034719 SMN-Sm protein complex(GO:0034719)
0.1 1.3 GO:0030008 TRAPP complex(GO:0030008)
0.1 0.8 GO:0097427 microtubule bundle(GO:0097427)
0.1 1.2 GO:0005839 proteasome core complex(GO:0005839)
0.1 3.0 GO:0090544 BAF-type complex(GO:0090544)
0.1 0.9 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 1.9 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 1.4 GO:0031527 filopodium membrane(GO:0031527)
0.1 1.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 1.0 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 1.5 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 0.9 GO:0000781 chromosome, telomeric region(GO:0000781)
0.1 0.9 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 3.2 GO:0005902 microvillus(GO:0005902)
0.1 2.6 GO:0035097 histone methyltransferase complex(GO:0035097)
0.1 1.0 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1 1.2 GO:0030914 STAGA complex(GO:0030914)
0.1 4.8 GO:0000776 kinetochore(GO:0000776)
0.1 0.5 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 1.2 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.3 GO:0043235 receptor complex(GO:0043235)
0.1 0.2 GO:0000439 core TFIIH complex(GO:0000439)
0.1 4.0 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 0.6 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.1 0.5 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.1 2.2 GO:0031519 PcG protein complex(GO:0031519)
0.1 5.1 GO:0005814 centriole(GO:0005814)
0.1 0.3 GO:0035253 ciliary rootlet(GO:0035253)
0.1 0.7 GO:0031083 BLOC-1 complex(GO:0031083)
0.1 2.8 GO:0031526 brush border membrane(GO:0031526)
0.0 1.8 GO:0000786 nucleosome(GO:0000786)
0.0 7.0 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 1.4 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 1.9 GO:0005903 brush border(GO:0005903)
0.0 2.2 GO:0005871 kinesin complex(GO:0005871)
0.0 3.1 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 0.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 3.3 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.6 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.7 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.3 GO:0061700 GATOR2 complex(GO:0061700)
0.0 2.9 GO:0030496 midbody(GO:0030496)
0.0 2.1 GO:0014704 intercalated disc(GO:0014704)
0.0 2.8 GO:0030426 growth cone(GO:0030426)
0.0 2.0 GO:0043197 dendritic spine(GO:0043197)
0.0 1.2 GO:0097546 ciliary base(GO:0097546)
0.0 1.4 GO:0016363 nuclear matrix(GO:0016363)
0.0 1.2 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.4 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.8 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.5 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 0.5 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.4 GO:0012505 endomembrane system(GO:0012505)
0.0 0.4 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 1.3 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.9 GO:0034707 chloride channel complex(GO:0034707)
0.0 1.2 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 2.2 GO:0055037 recycling endosome(GO:0055037)
0.0 0.4 GO:0005840 ribosome(GO:0005840)
0.0 1.9 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 0.4 GO:0002102 podosome(GO:0002102)
0.0 18.6 GO:0005739 mitochondrion(GO:0005739)
0.0 0.3 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.1 GO:0035859 Seh1-associated complex(GO:0035859)
0.0 1.1 GO:0005604 basement membrane(GO:0005604)
0.0 0.1 GO:0031143 pseudopodium(GO:0031143)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 8.8 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
2.7 40.0 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
2.1 10.4 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
1.9 5.7 GO:0098770 FBXO family protein binding(GO:0098770)
1.9 5.6 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
1.6 4.8 GO:0018738 S-formylglutathione hydrolase activity(GO:0018738)
1.6 12.6 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
1.6 6.2 GO:0016708 nitric oxide dioxygenase activity(GO:0008941) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor(GO:0016708) iron-cytochrome-c reductase activity(GO:0047726)
1.5 7.4 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
1.5 2.9 GO:0070905 serine binding(GO:0070905)
1.4 19.7 GO:0003688 DNA replication origin binding(GO:0003688)
1.4 4.1 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
1.3 9.1 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
1.3 5.2 GO:0050436 microfibril binding(GO:0050436)
1.3 6.3 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
1.2 3.7 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
1.2 4.9 GO:0003998 acylphosphatase activity(GO:0003998)
1.2 3.6 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
1.1 3.4 GO:0019779 Atg12 activating enzyme activity(GO:0019778) Atg8 activating enzyme activity(GO:0019779)
1.0 3.1 GO:0036470 tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478)
1.0 5.1 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
1.0 3.1 GO:0030158 protein xylosyltransferase activity(GO:0030158)
1.0 6.0 GO:0004920 interleukin-10 receptor activity(GO:0004920)
1.0 2.9 GO:0030368 interleukin-17 receptor activity(GO:0030368)
1.0 2.9 GO:0004828 serine-tRNA ligase activity(GO:0004828)
1.0 4.8 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
1.0 5.8 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
1.0 1.0 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.9 2.8 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.9 2.8 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.9 2.7 GO:0008732 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.9 5.2 GO:0030284 estrogen receptor activity(GO:0030284)
0.8 2.5 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.8 4.2 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.8 5.0 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.8 2.5 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.8 3.2 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.8 3.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.8 4.5 GO:0042731 PH domain binding(GO:0042731)
0.8 12.8 GO:0051010 microtubule plus-end binding(GO:0051010)
0.8 2.3 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.8 3.0 GO:0004921 interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970)
0.7 2.1 GO:0005436 sodium:phosphate symporter activity(GO:0005436) sodium:inorganic phosphate symporter activity(GO:0015319)
0.7 7.4 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.7 5.3 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.7 0.7 GO:0005402 cation:sugar symporter activity(GO:0005402)
0.6 2.6 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.6 2.4 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441)
0.6 2.4 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.6 1.8 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.6 8.9 GO:0016805 dipeptidase activity(GO:0016805)
0.6 7.7 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.6 1.8 GO:0003979 UDP-glucose 6-dehydrogenase activity(GO:0003979)
0.6 2.9 GO:0005290 L-histidine transmembrane transporter activity(GO:0005290)
0.6 1.7 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.6 2.3 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.6 6.8 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.6 1.7 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.6 2.8 GO:0034602 oxoglutarate dehydrogenase (NAD+) activity(GO:0034602)
0.6 2.2 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.5 4.3 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.5 3.8 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.5 2.1 GO:0035877 death effector domain binding(GO:0035877)
0.5 1.5 GO:0004936 alpha-adrenergic receptor activity(GO:0004936)
0.5 4.0 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.5 14.9 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.5 5.0 GO:0015266 protein channel activity(GO:0015266)
0.5 1.4 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.5 5.2 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.5 2.3 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.5 1.4 GO:0098973 structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.5 2.3 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.4 1.3 GO:0034618 arginine binding(GO:0034618)
0.4 2.2 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.4 3.0 GO:0000403 Y-form DNA binding(GO:0000403)
0.4 3.0 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.4 2.1 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.4 4.9 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.4 6.9 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.4 1.2 GO:0070140 isopeptidase activity(GO:0070122) ubiquitin-like protein-specific isopeptidase activity(GO:0070138) SUMO-specific isopeptidase activity(GO:0070140)
0.4 8.9 GO:0016675 oxidoreductase activity, acting on a heme group of donors(GO:0016675)
0.4 7.2 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.4 1.6 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.4 8.4 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.4 1.5 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.4 1.9 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.4 66.2 GO:0003735 structural constituent of ribosome(GO:0003735)
0.4 1.5 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.4 2.6 GO:0008428 ribonuclease inhibitor activity(GO:0008428)
0.4 12.2 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.4 1.8 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.4 1.8 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.3 1.4 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.3 1.7 GO:0030620 U2 snRNA binding(GO:0030620)
0.3 1.4 GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038)
0.3 2.0 GO:0048039 ubiquinone binding(GO:0048039)
0.3 1.0 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.3 3.9 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.3 1.0 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.3 2.9 GO:0044388 small protein activating enzyme binding(GO:0044388)
0.3 0.6 GO:0019153 protein-disulfide reductase (glutathione) activity(GO:0019153)
0.3 0.9 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.3 1.7 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.3 2.5 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.3 0.8 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.3 1.4 GO:0016531 metallochaperone activity(GO:0016530) copper chaperone activity(GO:0016531)
0.3 3.5 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.3 2.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.3 1.9 GO:0004075 biotin carboxylase activity(GO:0004075)
0.3 2.4 GO:0008420 CTD phosphatase activity(GO:0008420)
0.3 6.0 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.3 0.8 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.3 2.5 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.3 12.4 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.3 5.8 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.3 4.5 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.2 1.0 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.2 4.6 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.2 0.9 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.2 0.7 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.2 3.7 GO:0016594 glycine binding(GO:0016594)
0.2 1.4 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.2 1.4 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.2 2.5 GO:0008430 selenium binding(GO:0008430)
0.2 1.6 GO:0000150 recombinase activity(GO:0000150)
0.2 7.5 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.2 1.6 GO:0015099 nickel cation transmembrane transporter activity(GO:0015099)
0.2 4.5 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.2 2.5 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.2 3.8 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.2 1.5 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.2 9.5 GO:0016831 carboxy-lyase activity(GO:0016831)
0.2 0.9 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.2 2.0 GO:0005212 structural constituent of eye lens(GO:0005212)
0.2 4.1 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.2 1.1 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.2 9.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.2 1.0 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.2 1.6 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.2 2.8 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.2 2.9 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.2 3.1 GO:0070034 telomerase RNA binding(GO:0070034)
0.2 1.9 GO:0001055 RNA polymerase II activity(GO:0001055)
0.2 1.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.2 2.2 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.2 9.8 GO:0016651 oxidoreductase activity, acting on NAD(P)H(GO:0016651)
0.2 1.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.2 2.0 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.2 3.0 GO:0070402 NADPH binding(GO:0070402)
0.2 1.6 GO:0051434 BH3 domain binding(GO:0051434)
0.2 2.4 GO:0070300 phosphatidic acid binding(GO:0070300)
0.2 2.2 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.2 3.2 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.2 3.6 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.2 2.7 GO:1990226 histone methyltransferase binding(GO:1990226)
0.2 0.7 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.2 0.3 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.2 1.6 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.2 3.8 GO:0032183 SUMO binding(GO:0032183)
0.1 3.3 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.1 3.7 GO:0070182 DNA polymerase binding(GO:0070182)
0.1 2.5 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1 1.3 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.1 0.6 GO:0008422 beta-glucosidase activity(GO:0008422)
0.1 0.6 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.1 1.5 GO:0048185 activin binding(GO:0048185)
0.1 5.6 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 2.1 GO:0016504 peptidase activator activity(GO:0016504)
0.1 1.3 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.1 0.9 GO:0051400 BH domain binding(GO:0051400)
0.1 0.4 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.1 2.5 GO:0005521 lamin binding(GO:0005521)
0.1 2.9 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 0.5 GO:0050347 trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347)
0.1 0.2 GO:0051870 methotrexate binding(GO:0051870)
0.1 1.3 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 1.5 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.1 0.8 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 5.4 GO:0004112 cyclic-nucleotide phosphodiesterase activity(GO:0004112)
0.1 1.2 GO:1990405 protein antigen binding(GO:1990405)
0.1 13.5 GO:0003774 motor activity(GO:0003774)
0.1 2.5 GO:0043422 protein kinase B binding(GO:0043422)
0.1 3.7 GO:0070063 RNA polymerase binding(GO:0070063)
0.1 1.0 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.1 1.2 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.1 1.8 GO:0003951 NAD+ kinase activity(GO:0003951)
0.1 3.4 GO:0097472 cyclin-dependent protein kinase activity(GO:0097472)
0.1 0.6 GO:0050811 GABA receptor binding(GO:0050811)
0.1 0.6 GO:0050694 galactose 3-O-sulfotransferase activity(GO:0050694)
0.1 0.5 GO:0050544 arachidonic acid binding(GO:0050544)
0.1 1.7 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 0.3 GO:0001129 RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132)
0.1 1.6 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.1 8.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 1.5 GO:0005537 mannose binding(GO:0005537)
0.1 2.5 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 1.8 GO:0070628 proteasome binding(GO:0070628)
0.1 0.5 GO:0001032 RNA polymerase III type 3 promoter DNA binding(GO:0001032)
0.1 1.9 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.1 0.9 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.1 1.6 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.1 1.2 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 0.6 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1 0.3 GO:0016854 racemase and epimerase activity(GO:0016854)
0.1 1.6 GO:0035497 cAMP response element binding(GO:0035497)
0.1 2.0 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 2.8 GO:0005109 frizzled binding(GO:0005109)
0.1 1.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 1.7 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 0.2 GO:0043199 sulfate binding(GO:0043199)
0.1 0.9 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.1 2.0 GO:0031491 nucleosome binding(GO:0031491)
0.1 0.2 GO:0008176 tRNA (guanine-N7-)-methyltransferase activity(GO:0008176)
0.1 0.8 GO:0004497 monooxygenase activity(GO:0004497)
0.1 0.4 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.1 0.2 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.1 0.3 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1 23.6 GO:0045296 cadherin binding(GO:0045296)
0.1 10.4 GO:0019887 protein kinase regulator activity(GO:0019887)
0.1 2.1 GO:0042162 telomeric DNA binding(GO:0042162)
0.1 0.5 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 2.5 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 0.3 GO:0004104 cholinesterase activity(GO:0004104) choline binding(GO:0033265)
0.1 1.9 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.1 2.9 GO:0070888 E-box binding(GO:0070888)
0.1 1.2 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 0.2 GO:0008097 5S rRNA binding(GO:0008097)
0.1 1.0 GO:0034185 apolipoprotein binding(GO:0034185)
0.1 2.1 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 3.9 GO:0035064 methylated histone binding(GO:0035064)
0.1 1.4 GO:0070717 poly-purine tract binding(GO:0070717)
0.1 0.8 GO:0031490 chromatin DNA binding(GO:0031490)
0.1 0.4 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 3.7 GO:0002020 protease binding(GO:0002020)
0.1 1.1 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 9.9 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 2.2 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.1 1.0 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.6 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.3 GO:0008301 DNA binding, bending(GO:0008301)
0.0 1.4 GO:0005112 Notch binding(GO:0005112)
0.0 2.0 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 1.2 GO:0015295 solute:proton symporter activity(GO:0015295)
0.0 0.1 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.0 0.9 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.7 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.4 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 2.3 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 3.3 GO:0051015 actin filament binding(GO:0051015)
0.0 0.4 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.7 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 1.8 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.5 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 1.3 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 1.3 GO:0016835 carbon-oxygen lyase activity(GO:0016835)
0.0 1.0 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.5 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0 1.7 GO:0008237 metallopeptidase activity(GO:0008237)
0.0 1.6 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977)
0.0 2.1 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.3 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.5 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 3.0 GO:0000149 SNARE binding(GO:0000149)
0.0 1.4 GO:0051087 chaperone binding(GO:0051087)
0.0 0.3 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.4 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.5 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 1.1 GO:0032947 protein complex scaffold(GO:0032947)
0.0 0.4 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.5 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.7 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.3 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 2.4 GO:0005198 structural molecule activity(GO:0005198)
0.0 0.3 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.4 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.3 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 2.0 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.0 0.4 GO:0097602 cullin family protein binding(GO:0097602)
0.0 1.1 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 0.5 GO:0016209 antioxidant activity(GO:0016209)
0.0 0.4 GO:0016876 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.8 GO:0050660 flavin adenine dinucleotide binding(GO:0050660)
0.0 0.4 GO:0005504 fatty acid binding(GO:0005504)
0.0 1.0 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.4 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.5 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.3 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.2 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.8 GO:0001076 transcription factor activity, RNA polymerase II transcription factor binding(GO:0001076)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 9.5 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.6 18.3 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.6 4.1 SA_G1_AND_S_PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.5 25.2 PID_ATR_PATHWAY ATR signaling pathway
0.5 2.4 SA_PTEN_PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.4 16.5 PID_AURORA_A_PATHWAY Aurora A signaling
0.4 12.2 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.4 3.5 PID_NFKAPPAB_ATYPICAL_PATHWAY Atypical NF-kappaB pathway
0.3 13.4 PID_AURORA_B_PATHWAY Aurora B signaling
0.3 5.1 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.2 2.9 NABA_COLLAGENS Genes encoding collagen proteins
0.2 4.5 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.2 11.7 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.2 4.8 PID_MYC_PATHWAY C-MYC pathway
0.2 5.3 PID_ERBB2_ERBB3_PATHWAY ErbB2/ErbB3 signaling events
0.2 2.0 PID_ALK2_PATHWAY ALK2 signaling events
0.2 5.8 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.2 1.9 PID_S1P_S1P4_PATHWAY S1P4 pathway
0.2 5.6 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.2 15.5 SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.1 4.4 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.1 1.9 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.1 1.5 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin
0.1 5.0 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events
0.1 3.2 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.1 0.8 SA_FAS_SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 1.1 PID_AR_NONGENOMIC_PATHWAY Nongenotropic Androgen signaling
0.1 1.6 PID_SYNDECAN_2_PATHWAY Syndecan-2-mediated signaling events
0.1 3.8 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 2.8 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 5.9 PID_RB_1PATHWAY Regulation of retinoblastoma protein
0.1 2.7 PID_BARD1_PATHWAY BARD1 signaling events
0.1 2.3 ST_JNK_MAPK_PATHWAY JNK MAPK Pathway
0.1 4.4 PID_VEGFR1_2_PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.1 5.2 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.1 1.6 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.1 1.8 PID_P38_ALPHA_BETA_PATHWAY Regulation of p38-alpha and p38-beta
0.1 1.7 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.1 5.4 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.1 1.6 ST_TUMOR_NECROSIS_FACTOR_PATHWAY Tumor Necrosis Factor Pathway.
0.1 2.1 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.1 3.4 PID_REG_GR_PATHWAY Glucocorticoid receptor regulatory network
0.1 0.7 PID_IL23_PATHWAY IL23-mediated signaling events
0.1 1.8 PID_ECADHERIN_NASCENT_AJ_PATHWAY E-cadherin signaling in the nascent adherens junction
0.1 0.7 PID_IL12_2PATHWAY IL12-mediated signaling events
0.1 1.3 PID_INSULIN_PATHWAY Insulin Pathway
0.0 0.1 PID_IL27_PATHWAY IL27-mediated signaling events
0.0 0.5 SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES Genes related to the insulin receptor pathway
0.0 2.0 PID_E2F_PATHWAY E2F transcription factor network
0.0 1.9 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.0 0.8 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.0 0.6 PID_PRL_SIGNALING_EVENTS_PATHWAY Signaling events mediated by PRL
0.0 1.2 PID_CD8_TCR_DOWNSTREAM_PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 5.9 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.0 5.1 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.8 PID_ARF6_PATHWAY Arf6 signaling events
0.0 1.1 ST_FAS_SIGNALING_PATHWAY Fas Signaling Pathway
0.0 1.3 PID_P53_REGULATION_PATHWAY p53 pathway
0.0 0.7 PID_CXCR4_PATHWAY CXCR4-mediated signaling events
0.0 0.6 PID_FANCONI_PATHWAY Fanconi anemia pathway
0.0 1.2 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.0 0.6 PID_BMP_PATHWAY BMP receptor signaling
0.0 0.6 PID_HDAC_CLASSII_PATHWAY Signaling events mediated by HDAC Class II
0.0 0.3 ST_T_CELL_SIGNAL_TRANSDUCTION T Cell Signal Transduction
0.0 0.2 PID_NFAT_3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 21.2 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
1.2 19.8 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.9 19.7 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.8 2.5 REACTOME_SIGNALING_BY_CONSTITUTIVELY_ACTIVE_EGFR Genes involved in Signaling by constitutively active EGFR
0.8 4.7 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.7 5.2 REACTOME_REPAIR_SYNTHESIS_FOR_GAP_FILLING_BY_DNA_POL_IN_TC_NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.7 11.1 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.6 70.0 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.6 15.7 REACTOME_KINESINS Genes involved in Kinesins
0.5 11.2 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.5 4.9 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.5 1.5 REACTOME_HORMONE_LIGAND_BINDING_RECEPTORS Genes involved in Hormone ligand-binding receptors
0.5 27.1 REACTOME_SCFSKP2_MEDIATED_DEGRADATION_OF_P27_P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.4 2.8 REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.4 2.9 REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.3 4.8 REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM Genes involved in Cytokine Signaling in Immune system
0.3 5.5 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.3 9.6 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.3 6.9 REACTOME_METABOLISM_OF_NON_CODING_RNA Genes involved in Metabolism of non-coding RNA
0.3 18.7 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.3 16.5 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.3 3.6 REACTOME_GLUCAGON_TYPE_LIGAND_RECEPTORS Genes involved in Glucagon-type ligand receptors
0.2 4.0 REACTOME_FORMATION_OF_INCISION_COMPLEX_IN_GG_NER Genes involved in Formation of incision complex in GG-NER
0.2 4.1 REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.2 2.2 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.2 3.1 REACTOME_NFKB_ACTIVATION_THROUGH_FADD_RIP1_PATHWAY_MEDIATED_BY_CASPASE_8_AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.2 2.8 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.2 6.3 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.2 11.0 REACTOME_PHASE_II_CONJUGATION Genes involved in Phase II conjugation
0.2 2.8 REACTOME_EXTENSION_OF_TELOMERES Genes involved in Extension of Telomeres
0.2 17.3 REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.2 5.6 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.2 2.3 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.2 5.2 REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.2 3.1 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.2 2.9 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.2 6.5 REACTOME_ADP_SIGNALLING_THROUGH_P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.2 4.2 REACTOME_PYRUVATE_METABOLISM Genes involved in Pyruvate metabolism
0.2 5.7 REACTOME_G1_PHASE Genes involved in G1 Phase
0.2 5.7 REACTOME_IRON_UPTAKE_AND_TRANSPORT Genes involved in Iron uptake and transport
0.2 5.5 REACTOME_FATTY_ACYL_COA_BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.2 2.2 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 2.9 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 2.6 REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 12.4 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 1.6 REACTOME_ACTIVATION_OF_THE_PRE_REPLICATIVE_COMPLEX Genes involved in Activation of the pre-replicative complex
0.1 2.6 REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1 1.8 REACTOME_FANCONI_ANEMIA_PATHWAY Genes involved in Fanconi Anemia pathway
0.1 3.3 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.1 1.3 REACTOME_ELONGATION_ARREST_AND_RECOVERY Genes involved in Elongation arrest and recovery
0.1 1.2 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 5.8 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.1 1.5 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 2.6 REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.1 5.6 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening
0.1 2.3 REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.1 1.4 REACTOME_STEROID_HORMONES Genes involved in Steroid hormones
0.1 3.8 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 1.4 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 2.6 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 3.6 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 1.3 REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 1.2 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 0.9 REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION Genes involved in Extracellular matrix organization
0.1 2.2 REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1 1.0 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 1.1 REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.1 3.1 REACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING Genes involved in Pre-NOTCH Expression and Processing
0.1 1.2 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 1.2 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.1 1.6 REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS Genes involved in G alpha (z) signalling events
0.1 1.5 REACTOME_SPHINGOLIPID_METABOLISM Genes involved in Sphingolipid metabolism
0.1 5.0 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 1.7 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.1 0.9 REACTOME_PHOSPHORYLATION_OF_THE_APC_C Genes involved in Phosphorylation of the APC/C
0.1 0.9 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 2.5 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 1.0 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.1 1.2 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.4 REACTOME_DESTABILIZATION_OF_MRNA_BY_AUF1_HNRNP_D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.7 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.0 2.0 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 1.5 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 2.0 REACTOME_SIGNALING_BY_FGFR Genes involved in Signaling by FGFR
0.0 0.8 REACTOME_PYRIMIDINE_METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.8 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.6 REACTOME_DESTABILIZATION_OF_MRNA_BY_KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.8 REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 1.8 REACTOME_TRANSLATION Genes involved in Translation
0.0 0.9 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.3 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.3 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.5 REACTOME_DAG_AND_IP3_SIGNALING Genes involved in DAG and IP3 signaling
0.0 0.5 REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.4 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.4 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 1.1 REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.5 REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.4 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.0 0.7 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.1 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.8 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production