Motif ID: Pou2f1
Z-value: 0.669

Transcription factors associated with Pou2f1:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Pou2f1 | ENSMUSG00000026565.12 | Pou2f1 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Pou2f1 | mm10_v2_chr1_-_166002613_166002678 | -0.19 | 9.1e-02 | Click! |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 80 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 7.5 | GO:0010614 | negative regulation of cardiac muscle hypertrophy(GO:0010614) |
0.1 | 5.7 | GO:0008542 | visual learning(GO:0008542) |
0.3 | 3.8 | GO:0048934 | peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935) |
0.1 | 3.6 | GO:0045599 | negative regulation of fat cell differentiation(GO:0045599) |
1.1 | 3.4 | GO:0007521 | muscle cell fate determination(GO:0007521) cellular response to parathyroid hormone stimulus(GO:0071374) positive regulation of macrophage apoptotic process(GO:2000111) |
0.0 | 3.2 | GO:0000086 | G2/M transition of mitotic cell cycle(GO:0000086) |
0.1 | 3.1 | GO:0045063 | T-helper 1 cell differentiation(GO:0045063) |
0.0 | 2.7 | GO:0051965 | positive regulation of synapse assembly(GO:0051965) |
0.0 | 2.5 | GO:0002377 | immunoglobulin production(GO:0002377) |
0.0 | 2.5 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
0.7 | 2.0 | GO:0051754 | meiotic sister chromatid cohesion, centromeric(GO:0051754) |
0.0 | 2.0 | GO:0006342 | chromatin silencing(GO:0006342) |
0.1 | 1.9 | GO:0006883 | cellular sodium ion homeostasis(GO:0006883) |
0.6 | 1.7 | GO:0072284 | cervix development(GO:0060067) metanephric S-shaped body morphogenesis(GO:0072284) anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744) |
0.1 | 1.7 | GO:0043552 | positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552) |
0.3 | 1.6 | GO:0097680 | double-strand break repair via classical nonhomologous end joining(GO:0097680) |
0.4 | 1.5 | GO:0019287 | isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287) |
0.3 | 1.5 | GO:1903378 | positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378) |
0.3 | 1.4 | GO:0034421 | post-translational protein acetylation(GO:0034421) |
0.1 | 1.4 | GO:0006910 | phagocytosis, recognition(GO:0006910) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 50 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 7.3 | GO:0016605 | PML body(GO:0016605) |
0.0 | 5.2 | GO:0043679 | axon terminus(GO:0043679) |
0.0 | 3.6 | GO:0016363 | nuclear matrix(GO:0016363) |
0.0 | 3.4 | GO:0030017 | sarcomere(GO:0030017) |
0.6 | 2.8 | GO:0000308 | cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308) |
0.5 | 2.0 | GO:0000942 | condensed nuclear chromosome outer kinetochore(GO:0000942) |
0.3 | 1.6 | GO:0005958 | DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807) |
0.4 | 1.5 | GO:1990452 | Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452) |
0.1 | 1.4 | GO:0042571 | immunoglobulin complex, circulating(GO:0042571) |
0.1 | 1.4 | GO:0031618 | nuclear pericentric heterochromatin(GO:0031618) |
0.0 | 1.4 | GO:0032391 | photoreceptor connecting cilium(GO:0032391) |
0.2 | 1.1 | GO:0097149 | centralspindlin complex(GO:0097149) |
0.2 | 1.1 | GO:0000235 | astral microtubule(GO:0000235) |
0.1 | 1.1 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) |
0.0 | 1.1 | GO:0030285 | integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563) |
0.3 | 1.0 | GO:0070022 | transforming growth factor beta receptor homodimeric complex(GO:0070022) |
0.0 | 1.0 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
0.0 | 1.0 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
0.1 | 0.9 | GO:0035686 | sperm fibrous sheath(GO:0035686) |
0.0 | 0.9 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 70 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 7.3 | GO:0001191 | transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191) |
0.3 | 5.7 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
0.0 | 3.6 | GO:0003714 | transcription corepressor activity(GO:0003714) |
0.2 | 3.4 | GO:0003680 | AT DNA binding(GO:0003680) |
0.0 | 3.3 | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) |
0.1 | 2.8 | GO:0030332 | cyclin binding(GO:0030332) |
0.0 | 1.9 | GO:0004879 | RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531) |
0.1 | 1.7 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
0.0 | 1.7 | GO:0004843 | thiol-dependent ubiquitin-specific protease activity(GO:0004843) |
0.3 | 1.6 | GO:0003910 | DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910) |
0.3 | 1.5 | GO:0050816 | phosphothreonine binding(GO:0050816) |
0.2 | 1.4 | GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468) |
0.1 | 1.4 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
0.3 | 1.2 | GO:0030348 | syntaxin-3 binding(GO:0030348) |
0.0 | 1.1 | GO:0043539 | protein serine/threonine kinase activator activity(GO:0043539) |
0.0 | 1.1 | GO:0008307 | structural constituent of muscle(GO:0008307) |
0.0 | 1.1 | GO:0004540 | ribonuclease activity(GO:0004540) |
0.0 | 1.1 | GO:0017048 | Rho GTPase binding(GO:0017048) |
0.3 | 1.0 | GO:0004510 | tryptophan 5-monooxygenase activity(GO:0004510) |
0.1 | 1.0 | GO:0035615 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
Gene overrepresentation in C2:CP category:
Showing 1 to 20 of 23 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 5.7 | PID_AP1_PATHWAY | AP-1 transcription factor network |
0.1 | 3.8 | PID_AURORA_B_PATHWAY | Aurora B signaling |
0.0 | 3.8 | NABA_ECM_AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
0.1 | 3.4 | PID_MAPK_TRK_PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
0.1 | 3.2 | PID_P38_MK2_PATHWAY | p38 signaling mediated by MAPKAP kinases |
0.0 | 3.2 | NABA_SECRETED_FACTORS | Genes encoding secreted soluble factors |
0.1 | 1.7 | SA_B_CELL_RECEPTOR_COMPLEXES | Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases. |
0.1 | 1.6 | PID_DNA_PK_PATHWAY | DNA-PK pathway in nonhomologous end joining |
0.1 | 1.5 | PID_MYC_PATHWAY | C-MYC pathway |
0.0 | 1.2 | SIG_CD40PATHWAYMAP | Genes related to CD40 signaling |
0.0 | 1.1 | PID_GLYPICAN_1PATHWAY | Glypican 1 network |
0.0 | 1.1 | PID_FCER1_PATHWAY | Fc-epsilon receptor I signaling in mast cells |
0.0 | 1.1 | PID_PLK1_PATHWAY | PLK1 signaling events |
0.0 | 1.0 | PID_TGFBR_PATHWAY | TGF-beta receptor signaling |
0.0 | 0.9 | PID_SHP2_PATHWAY | SHP2 signaling |
0.0 | 0.9 | PID_RAC1_PATHWAY | RAC1 signaling pathway |
0.0 | 0.7 | PID_IL5_PATHWAY | IL5-mediated signaling events |
0.0 | 0.7 | PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY | Signaling mediated by p38-alpha and p38-beta |
0.0 | 0.6 | PID_HEDGEHOG_GLI_PATHWAY | Hedgehog signaling events mediated by Gli proteins |
0.0 | 0.4 | PID_P38_MKK3_6PATHWAY | p38 MAPK signaling pathway |
Gene overrepresentation in C2:CP:REACTOME category:
Showing 1 to 20 of 30 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 4.6 | REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS | Genes involved in Peptide ligand-binding receptors |
0.1 | 3.4 | REACTOME_ERK_MAPK_TARGETS | Genes involved in ERK/MAPK targets |
0.1 | 3.1 | REACTOME_OTHER_SEMAPHORIN_INTERACTIONS | Genes involved in Other semaphorin interactions |
0.0 | 2.9 | REACTOME_MITOTIC_PROMETAPHASE | Genes involved in Mitotic Prometaphase |
0.0 | 2.6 | REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
0.0 | 2.2 | REACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE | Genes involved in GPVI-mediated activation cascade |
0.1 | 2.1 | REACTOME_PACKAGING_OF_TELOMERE_ENDS | Genes involved in Packaging Of Telomere Ends |
0.1 | 1.9 | REACTOME_CHOLESTEROL_BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
0.1 | 1.6 | REACTOME_INTEGRATION_OF_PROVIRUS | Genes involved in Integration of provirus |
0.0 | 1.6 | REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS | Genes involved in Adherens junctions interactions |
0.0 | 1.5 | REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
0.1 | 1.2 | REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE | Genes involved in Acetylcholine Neurotransmitter Release Cycle |
0.0 | 1.1 | REACTOME_STRIATED_MUSCLE_CONTRACTION | Genes involved in Striated Muscle Contraction |
0.1 | 1.0 | REACTOME_AMINE_DERIVED_HORMONES | Genes involved in Amine-derived hormones |
0.1 | 1.0 | REACTOME_GAP_JUNCTION_DEGRADATION | Genes involved in Gap junction degradation |
0.0 | 0.9 | REACTOME_N_GLYCAN_ANTENNAE_ELONGATION | Genes involved in N-Glycan antennae elongation |
0.1 | 0.8 | REACTOME_PROLACTIN_RECEPTOR_SIGNALING | Genes involved in Prolactin receptor signaling |
0.0 | 0.7 | REACTOME_ACTIVATION_OF_RAC | Genes involved in Activation of Rac |
0.0 | 0.7 | REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA | Genes involved in Circadian Repression of Expression by REV-ERBA |
0.0 | 0.7 | REACTOME_GLYCOLYSIS | Genes involved in Glycolysis |