Motif ID: Pou2f3

Z-value: 0.739


Transcription factors associated with Pou2f3:

Gene SymbolEntrez IDGene Name
Pou2f3 ENSMUSG00000032015.9 Pou2f3



Activity profile for motif Pou2f3.

activity profile for motif Pou2f3


Sorted Z-values histogram for motif Pou2f3

Sorted Z-values for motif Pou2f3



Network of associatons between targets according to the STRING database.



First level regulatory network of Pou2f3

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_+_66219909 5.826 ENSMUST00000029421.5
 Ptx3
pentraxin related gene
chrX_-_23266751 5.523 ENSMUST00000115316.2
 Klhl13
kelch-like 13
chr9_-_58313189 4.941 ENSMUST00000061799.8
 Loxl1
lysyl oxidase-like 1
chr13_+_94173992 4.509 ENSMUST00000121618.1
 Lhfpl2
lipoma HMGIC fusion partner-like 2
chr3_+_53845086 3.777 ENSMUST00000108014.1
 Gm10985
predicted gene 10985
chr6_-_23248264 3.357 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr6_+_34476207 3.235 ENSMUST00000045372.5
ENSMUST00000138668.1
ENSMUST00000139067.1
 Bpgm


2,3-bisphosphoglycerate mutase


chr18_-_82406777 3.066 ENSMUST00000065224.6
 Galr1
galanin receptor 1
chr1_-_144177259 2.706 ENSMUST00000111941.1
ENSMUST00000052375.1
 Rgs13

regulator of G-protein signaling 13

chr10_+_26229707 2.694 ENSMUST00000060716.5
ENSMUST00000164660.1
 Samd3

sterile alpha motif domain containing 3

chr15_-_78773452 2.677 ENSMUST00000018313.5
 Mfng
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr3_-_63851251 2.608 ENSMUST00000162269.2
ENSMUST00000159676.2
ENSMUST00000175947.1
 Plch1


phospholipase C, eta 1


chrX_+_142227923 2.403 ENSMUST00000042329.5
 Nxt2
nuclear transport factor 2-like export factor 2
chr1_-_166002613 2.350 ENSMUST00000177358.1
ENSMUST00000160908.1
ENSMUST00000027850.8
ENSMUST00000160260.2
 Pou2f1



POU domain, class 2, transcription factor 1



chr6_+_125215551 2.333 ENSMUST00000032487.7
ENSMUST00000100942.2
ENSMUST00000063588.8
 Vamp1


vesicle-associated membrane protein 1


chr5_-_109558957 2.283 ENSMUST00000044579.7
 Crlf2
cytokine receptor-like factor 2
chr12_+_118846329 2.283 ENSMUST00000063918.2
 Sp8
trans-acting transcription factor 8
chr12_+_38780284 2.240 ENSMUST00000162563.1
ENSMUST00000161164.1
ENSMUST00000160996.1
 Etv1


ets variant gene 1


chr14_+_26122609 2.220 ENSMUST00000100810.6
 Duxbl2
doubl homeobox B-like 2
chrX_+_142228177 2.200 ENSMUST00000112914.1
 Nxt2
nuclear transport factor 2-like export factor 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 96 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 5.9 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
1.2 5.8 GO:0052428 modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.0 4.8 GO:0000910 cytokinesis(GO:0000910)
0.0 4.0 GO:0051028 mRNA transport(GO:0051028)
0.6 3.7 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.6 3.4 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
1.1 3.2 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
1.0 3.1 GO:0051464 positive regulation of cortisol secretion(GO:0051464)
0.3 2.7 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 2.4 GO:0048015 phosphatidylinositol-mediated signaling(GO:0048015) inositol lipid-mediated signaling(GO:0048017)
0.3 2.3 GO:0035745 T-helper 2 cell cytokine production(GO:0035745)
0.1 2.3 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 2.2 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.3 2.1 GO:0060923 cardiac muscle cell fate commitment(GO:0060923)
0.0 2.0 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.6 1.9 GO:0019343 cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344)
0.3 1.9 GO:2001170 negative regulation of ATP biosynthetic process(GO:2001170)
0.1 1.9 GO:0035493 SNARE complex assembly(GO:0035493)
0.1 1.8 GO:1904707 positive regulation of vascular smooth muscle cell proliferation(GO:1904707)
0.0 1.8 GO:0006940 regulation of smooth muscle contraction(GO:0006940)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 42 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 4.9 GO:0005604 basement membrane(GO:0005604)
0.0 3.7 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.1 2.8 GO:0005605 basal lamina(GO:0005605)
0.1 2.6 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.5 2.3 GO:0070820 tertiary granule(GO:0070820)
0.0 2.0 GO:0005657 replication fork(GO:0005657)
0.4 1.9 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.2 1.8 GO:0030478 actin cap(GO:0030478)
0.2 1.7 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.2 1.5 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.2 1.5 GO:0043219 lateral loop(GO:0043219)
0.4 1.4 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.3 1.3 GO:1990357 terminal web(GO:1990357)
0.1 1.3 GO:0000974 Prp19 complex(GO:0000974)
0.0 1.3 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 1.2 GO:0035861 site of double-strand break(GO:0035861)
0.2 1.1 GO:0032133 chromosome passenger complex(GO:0032133)
0.1 1.0 GO:0001739 sex chromatin(GO:0001739)
0.1 0.9 GO:0016035 zeta DNA polymerase complex(GO:0016035)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 66 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 5.8 GO:0001849 complement component C1q binding(GO:0001849)
0.4 4.9 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 4.6 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 3.7 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
1.1 3.2 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.8 3.1 GO:0004966 galanin receptor activity(GO:0004966)
0.9 2.7 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 2.6 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 2.5 GO:0005112 Notch binding(GO:0005112)
0.1 2.3 GO:0005484 SNAP receptor activity(GO:0005484)
0.6 1.9 GO:0098809 nitrite reductase activity(GO:0098809)
0.2 1.9 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
0.6 1.8 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661)
0.0 1.8 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.2 1.7 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.1 1.7 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.1 1.5 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 1.5 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.3 1.4 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.3 1.4 GO:0050816 phosphothreonine binding(GO:0050816)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 21 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 7.2 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 6.7 PID_AURORA_B_PATHWAY Aurora B signaling
0.1 5.8 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 5.2 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 2.8 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 2.5 PID_NOTCH_PATHWAY Notch signaling pathway
0.0 2.2 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 2.1 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.1 2.0 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.5 PID_AP1_PATHWAY AP-1 transcription factor network
0.0 1.5 SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES Genes related to the insulin receptor pathway
0.0 1.3 PID_MYC_PATHWAY C-MYC pathway
0.0 1.2 ST_P38_MAPK_PATHWAY p38 MAPK Pathway
0.0 1.0 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.0 0.8 PID_IL27_PATHWAY IL27-mediated signaling events
0.0 0.8 PID_ANGIOPOIETIN_RECEPTOR_PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.7 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.7 PID_E2F_PATHWAY E2F transcription factor network
0.0 0.6 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.0 0.5 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 31 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.7 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1 3.8 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 3.1 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.2 2.7 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.2 2.5 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.2 2.3 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 1.8 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 1.7 REACTOME_BASIGIN_INTERACTIONS Genes involved in Basigin interactions
0.0 1.7 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 1.6 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 1.5 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.1 1.3 REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 1.3 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.1 1.2 REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.4 1.1 REACTOME_APC_C_CDH1_MEDIATED_DEGRADATION_OF_CDC20_AND_OTHER_APC_C_CDH1_TARGETED_PROTEINS_IN_LATE_MITOSIS_EARLY_G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.1 1.1 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 1.1 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.0 1.1 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 1.0 REACTOME_GLYCOSPHINGOLIPID_METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.9 REACTOME_DNA_REPAIR Genes involved in DNA Repair