• All motifs sorted by activity significance
• All samples sorted alphabetically
• Mean activities
• All promoters sorted by FOV

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
• Download the whole report

Motif ID: Pou3f2

Z-value: 1.041

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr7_+_51621830	19.512	ENSMUST00000032710.5	Slc17a6	solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6
chr6_-_23248264	13.514	ENSMUST00000031709.5	Fezf1	Fez family zinc finger 1
chr19_+_60144682	11.699	ENSMUST00000065383.4	E330013P04Rik	RIKEN cDNA E330013P04 gene
chr4_-_110286581	11.538	ENSMUST00000138972.1	Elavl4	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr14_-_47418407	11.197	ENSMUST00000043296.3	Dlgap5	discs, large (Drosophila) homolog-associated protein 5
chr18_+_5593566	11.156	ENSMUST00000160910.1	Zeb1	zinc finger E-box binding homeobox 1
chr11_+_23256566	9.959	ENSMUST00000136235.1	Xpo1	exportin 1, CRM1 homolog (yeast)
chr3_-_36571952	9.917	ENSMUST00000029270.3	Ccna2	cyclin A2
chr2_-_60125651	9.339	ENSMUST00000112550.1	Baz2b	bromodomain adjacent to zinc finger domain, 2B
chr4_-_109665249	9.279	ENSMUST00000063531.4	Cdkn2c	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
chr16_-_36784784	8.214	ENSMUST00000165531.1	Slc15a2	solute carrier family 15 (H+/peptide transporter), member 2
chr16_-_36784924	7.474	ENSMUST00000168279.1 ENSMUST00000164579.1 ENSMUST00000023616.2	Slc15a2	solute carrier family 15 (H+/peptide transporter), member 2
chr2_-_62483637	6.976	ENSMUST00000136686.1 ENSMUST00000102733.3	Gcg	glucagon
chr10_-_69352886	6.960	ENSMUST00000119827.1 ENSMUST00000020099.5	Cdk1	cyclin-dependent kinase 1
chrX_-_145505136	6.595	ENSMUST00000112835.1	Amot	angiomotin
chr14_+_99046406	6.404	ENSMUST00000022656.6	Bora	bora, aurora kinase A activator
chr3_+_88207308	6.296	ENSMUST00000180582.1	Gm3764	predicted gene 3764
chrX_-_145505175	6.126	ENSMUST00000143610.1	Amot	angiomotin
chr3_+_88206786	6.091	ENSMUST00000181134.1 ENSMUST00000181550.1	Gm3764	predicted gene 3764
chr1_-_139377094	5.843	ENSMUST00000131586.1 ENSMUST00000145244.1	Crb1	crumbs homolog 1 (Drosophila)
chr19_+_38930909	5.616	ENSMUST00000025965.5	Hells	helicase, lymphoid specific
chr12_+_52699297	5.451	ENSMUST00000095737.3	Akap6	A kinase (PRKA) anchor protein 6
chr7_+_75610038	5.313	ENSMUST00000125771.1	Akap13	A kinase (PRKA) anchor protein 13
chr14_+_84443553	5.064	ENSMUST00000071370.5	Pcdh17	protocadherin 17
chrX_-_162159717	4.885	ENSMUST00000087085.3	Nhs	Nance-Horan syndrome (human)
chr12_-_91384403	4.334	ENSMUST00000141429.1	Cep128	centrosomal protein 128
chr6_+_34384218	4.238	ENSMUST00000038383.7 ENSMUST00000115051.1	Akr1b10	aldo-keto reductase family 1, member B10 (aldose reductase)
chr1_+_150392794	4.225	ENSMUST00000124973.2	Tpr	translocated promoter region
chr13_+_44840686	4.193	ENSMUST00000173906.1	Jarid2	jumonji, AT rich interactive domain 2
chr9_-_105521147	3.776	ENSMUST00000176770.1 ENSMUST00000085133.6	Atp2c1	ATPase, Ca++-sequestering
chr2_+_61593077	3.776	ENSMUST00000112495.1 ENSMUST00000112501.2	Tank	TRAF family member-associated Nf-kappa B activator
chr3_-_157925056	3.696	ENSMUST00000118539.1	Cth	cystathionase (cystathionine gamma-lyase)
chr5_-_111761697	3.652	ENSMUST00000129146.1 ENSMUST00000137398.1 ENSMUST00000129065.1	E130006D01Rik	RIKEN cDNA E130006D01 gene
chr16_+_36875119	3.642	ENSMUST00000135406.1 ENSMUST00000114812.1 ENSMUST00000134616.1 ENSMUST00000023534.6	Golgb1 Golgb1	golgi autoantigen, golgin subfamily b, macrogolgin 1 golgi autoantigen, golgin subfamily b, macrogolgin 1
chr12_+_71170589	3.445	ENSMUST00000129376.1	2700049A03Rik	RIKEN cDNA 2700049A03 gene
chr14_-_88471396	3.441	ENSMUST00000061628.5	Pcdh20	protocadherin 20
chr3_+_88965812	3.430	ENSMUST00000090933.4	Ash1l	ash1 (absent, small, or homeotic)-like (Drosophila)
chr1_+_74661714	3.376	ENSMUST00000042125.8 ENSMUST00000141119.1	Ttll4	tubulin tyrosine ligase-like family, member 4
chr18_+_4920509	3.124	ENSMUST00000126977.1	Svil	supervillin
chr15_+_36179530	3.097	ENSMUST00000171205.1	Spag1	sperm associated antigen 1
chr7_-_140822124	3.090	ENSMUST00000106052.1 ENSMUST00000080651.6	Zfp941	zinc finger protein 941
chr11_+_23256001	2.965	ENSMUST00000020538.6 ENSMUST00000109551.1 ENSMUST00000102870.1 ENSMUST00000102869.1	Xpo1	exportin 1, CRM1 homolog (yeast)
chr2_+_80315461	2.938	ENSMUST00000028392.7	Dnajc10	DnaJ (Hsp40) homolog, subfamily C, member 10
chr1_+_74661794	2.829	ENSMUST00000129890.1	Ttll4	tubulin tyrosine ligase-like family, member 4
chr8_-_41041828	2.764	ENSMUST00000051379.7	Mtus1	mitochondrial tumor suppressor 1
chr3_+_95929246	2.635	ENSMUST00000165307.1 ENSMUST00000015893.6	Anp32e	acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr14_-_16575456	2.626	ENSMUST00000063750.6	Rarb	retinoic acid receptor, beta
chr7_-_133015248	2.616	ENSMUST00000169570.1	Ctbp2	C-terminal binding protein 2
chr10_+_57794335	2.545	ENSMUST00000151623.1 ENSMUST00000020022.7	Smpdl3a	sphingomyelin phosphodiesterase, acid-like 3A
chr3_+_95929325	2.281	ENSMUST00000171368.1 ENSMUST00000168106.1	Anp32e	acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr10_-_53630439	2.228	ENSMUST00000075540.5	Mcm9	minichromosome maintenance complex component 9
chr14_+_79515618	2.134	ENSMUST00000110835.1	Elf1	E74-like factor 1
chr9_+_44981779	1.996	ENSMUST00000034602.7	Cd3d	CD3 antigen, delta polypeptide
chr9_+_88839164	1.983	ENSMUST00000163255.2	Trim43c	tripartite motif-containing 43C
chr8_+_85171322	1.960	ENSMUST00000076896.5	Gm6531	predicted gene 6531
chr1_-_150465563	1.938	ENSMUST00000164600.1 ENSMUST00000111902.2 ENSMUST00000111901.2 ENSMUST00000006171.9	Prg4	proteoglycan 4 (megakaryocyte stimulating factor, articular superficial zone protein)
chr3_-_51560816	1.828	ENSMUST00000037141.7	Setd7	SET domain containing (lysine methyltransferase) 7
chr7_+_16781341	1.801	ENSMUST00000108496.2	Slc1a5	solute carrier family 1 (neutral amino acid transporter), member 5
chr1_-_156036473	1.700	ENSMUST00000097527.3 ENSMUST00000027738.7	Tor1aip1	torsin A interacting protein 1
chr12_-_31351368	1.674	ENSMUST00000110857.3	Dld	dihydrolipoamide dehydrogenase
chr11_-_98625661	1.659	ENSMUST00000104933.1	Gm12355	predicted gene 12355
chr2_+_140152043	1.545	ENSMUST00000104994.2	Gm17374	predicted gene, 17374
chr9_+_88581036	1.427	ENSMUST00000164661.2	Trim43a	tripartite motif-containing 43A
chrX_+_164419782	1.409	ENSMUST00000033754.7	Piga	phosphatidylinositol glycan anchor biosynthesis, class A
chr8_-_41054771	1.328	ENSMUST00000093534.4	Mtus1	mitochondrial tumor suppressor 1
chr17_-_83514311	1.316	ENSMUST00000167741.1 ENSMUST00000025095.7	Cox7a2l	cytochrome c oxidase subunit VIIa polypeptide 2-like
chr5_+_86804508	1.256	ENSMUST00000038384.7	Ythdc1	YTH domain containing 1
chr9_-_89092835	1.219	ENSMUST00000167113.1	Trim43b	tripartite motif-containing 43B
chr1_-_52490736	1.209	ENSMUST00000170269.1	Nab1	Ngfi-A binding protein 1
chr2_-_136387929	1.196	ENSMUST00000035264.2 ENSMUST00000077200.3	Pak7	p21 protein (Cdc42/Rac)-activated kinase 7
chr1_-_150392719	1.189	ENSMUST00000006167.6 ENSMUST00000094477.2 ENSMUST00000097547.3	BC003331	cDNA sequence BC003331
chr14_+_73138755	1.124	ENSMUST00000171070.1	Rcbtb2	regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr6_-_99632376	1.124	ENSMUST00000176255.1	Gm20696	predicted gene 20696
chr12_+_51377560	1.106	ENSMUST00000021335.5	Scfd1	Sec1 family domain containing 1
chrX_+_96456362	1.073	ENSMUST00000079322.5 ENSMUST00000113838.1	Heph	hephaestin
chr4_+_11758147	1.013	ENSMUST00000029871.5 ENSMUST00000108303.1	Cdh17	cadherin 17
chr6_+_29694204	0.964	ENSMUST00000046750.7 ENSMUST00000115250.3	Tspan33	tetraspanin 33
chr2_+_104590453	0.942	ENSMUST00000028599.7	Cstf3	cleavage stimulation factor, 3' pre-RNA, subunit 3
chr17_-_24163668	0.939	ENSMUST00000040735.5	Amdhd2	amidohydrolase domain containing 2
chr3_+_66985680	0.914	ENSMUST00000065047.6	Rsrc1	arginine/serine-rich coiled-coil 1
chr5_+_14025305	0.898	ENSMUST00000073957.6	Sema3e	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr11_-_23519181	0.896	ENSMUST00000020527.5	1700093K21Rik	RIKEN cDNA 1700093K21 gene
chr18_-_43477764	0.747	ENSMUST00000057110.9	Eif3j2	eukaryotic translation initiation factor 3, subunit J2
chr6_-_134887783	0.743	ENSMUST00000066107.6	Gpr19	G protein-coupled receptor 19
chr7_+_119690026	0.611	ENSMUST00000047045.8	Acsm4	acyl-CoA synthetase medium-chain family member 4
chr16_-_17561240	0.434	ENSMUST00000065125.5 ENSMUST00000100123.3 ENSMUST00000023442.6	4930451C15Rik	RIKEN cDNA 4930451C15 gene
chr5_+_107497762	0.391	ENSMUST00000152474.1 ENSMUST00000060553.7	A830010M20Rik	RIKEN cDNA A830010M20 gene
chr17_-_6449571	0.354	ENSMUST00000180035.1	Tmem181b-ps	transmembrane protein 181B, pseudogene
chr16_+_44867097	0.350	ENSMUST00000102805.3	Cd200r2	Cd200 receptor 2
chr3_+_66985700	0.244	ENSMUST00000046542.6 ENSMUST00000162693.1	Rsrc1	arginine/serine-rich coiled-coil 1
chr5_+_107497718	0.224	ENSMUST00000112671.2	A830010M20Rik	RIKEN cDNA A830010M20 gene
chr19_+_47067721	0.212	ENSMUST00000026027.5	Taf5	TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr3_+_103809520	0.187	ENSMUST00000076599.1 ENSMUST00000106824.1 ENSMUST00000106823.1 ENSMUST00000047285.2	Ap4b1	adaptor-related protein complex AP-4, beta 1
chr16_-_36874806	0.093	ENSMUST00000075946.5	Eaf2	ELL associated factor 2
chr5_-_24527276	0.067	ENSMUST00000088311.4	Gbx1	gastrulation brain homeobox 1
chr6_+_8209216	0.061	ENSMUST00000040017.7	Mios	missing oocyte, meiosis regulator, homolog (Drosophila)
chr3_+_66985947	0.041	ENSMUST00000161726.1 ENSMUST00000160504.1	Rsrc1	arginine/serine-rich coiled-coil 1
chr1_+_167618246	0.027	ENSMUST00000111380.1	Rxrg	retinoid X receptor gamma
chr2_-_84650760	0.024	ENSMUST00000111691.1	Ctnnd1	catenin (cadherin associated protein), delta 1
chr19_+_44203265	0.005	ENSMUST00000026220.5	Scd3	stearoyl-coenzyme A desaturase 3

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.2	12.7	GO:0003365	establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
3.1	15.7	GO:0042891	antibiotic transport(GO:0042891) dipeptide transport(GO:0042938)
2.3	13.5	GO:0021797	forebrain anterior/posterior pattern specification(GO:0021797)
2.2	19.5	GO:0098700	neurotransmitter loading into synaptic vesicle(GO:0098700)
1.6	12.9	GO:0000056	ribosomal small subunit export from nucleus(GO:0000056)
1.4	4.2	GO:0032240	RNA import into nucleus(GO:0006404) mRNA export from nucleus in response to heat stress(GO:0031990) negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
1.4	5.5	GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
1.2	11.2	GO:0048752	semicircular canal morphogenesis(GO:0048752)
1.2	3.7	GO:0019343	cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344)
1.0	7.0	GO:0035948	positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072366)
0.9	3.8	GO:0055071	cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071)
0.9	3.8	GO:2000158	positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.9	5.3	GO:0071883	activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.8	5.6	GO:0031508	pericentric heterochromatin assembly(GO:0031508)
0.8	7.0	GO:0090166	Golgi disassembly(GO:0090166)
0.7	6.2	GO:0018095	protein polyglutamylation(GO:0018095)
0.6	1.7	GO:0009106	lipoate metabolic process(GO:0009106)
0.5	3.4	GO:0002674	negative regulation of acute inflammatory response(GO:0002674)
0.5	1.9	GO:0045409	negative regulation of interleukin-6 biosynthetic process(GO:0045409)
0.5	1.8	GO:0015825	L-serine transport(GO:0015825)
0.4	2.6	GO:0003406	retinal pigment epithelium development(GO:0003406)
0.4	2.9	GO:0034975	protein folding in endoplasmic reticulum(GO:0034975)
0.4	2.5	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.4	5.1	GO:2000807	regulation of synaptic vesicle clustering(GO:2000807)
0.3	9.3	GO:0045736	negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.3	1.0	GO:0002314	germinal center B cell differentiation(GO:0002314)
0.3	4.2	GO:0051574	positive regulation of histone H3-K9 methylation(GO:0051574)
0.3	9.9	GO:0016572	histone phosphorylation(GO:0016572)
0.3	2.6	GO:0048386	positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.2	1.8	GO:0018026	peptidyl-lysine monomethylation(GO:0018026)
0.2	2.0	GO:0045059	positive thymic T cell selection(GO:0045059)
0.2	4.9	GO:0043486	histone exchange(GO:0043486)
0.2	6.4	GO:0060236	regulation of mitotic spindle organization(GO:0060236)
0.2	1.7	GO:0071763	nuclear membrane organization(GO:0071763)
0.2	2.1	GO:0050860	negative regulation of T cell receptor signaling pathway(GO:0050860)
0.2	4.1	GO:0010758	regulation of macrophage chemotaxis(GO:0010758)
0.2	0.9	GO:1901072	glucosamine-containing compound catabolic process(GO:1901072)
0.1	11.5	GO:0043488	regulation of mRNA stability(GO:0043488)
0.1	4.2	GO:0042462	eye photoreceptor cell development(GO:0042462)
0.1	1.1	GO:1902902	negative regulation of autophagosome assembly(GO:1902902)
0.1	1.3	GO:0002082	regulation of oxidative phosphorylation(GO:0002082)
0.1	2.2	GO:0006270	DNA replication initiation(GO:0006270)
0.1	4.1	GO:0002088	lens development in camera-type eye(GO:0002088)
0.0	3.4	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0	3.1	GO:0007338	single fertilization(GO:0007338)
0.0	1.2	GO:0036075	endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0	1.4	GO:0006506	GPI anchor biosynthetic process(GO:0006506)
0.0	1.0	GO:0046677	response to antibiotic(GO:0046677)
0.0	1.3	GO:0006376	mRNA splice site selection(GO:0006376)
0.0	0.9	GO:0006379	mRNA cleavage(GO:0006379)
0.0	0.9	GO:2000249	regulation of actin cytoskeleton reorganization(GO:2000249)
0.0	0.1	GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0	0.1	GO:0019230	proprioception(GO:0019230)
0.0	3.4	GO:0007224	smoothened signaling pathway(GO:0007224)
0.0	3.1	GO:0007519	skeletal muscle tissue development(GO:0007519)
0.0	0.2	GO:0006367	transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0	1.0	GO:0072659	protein localization to plasma membrane(GO:0072659) protein localization to cell periphery(GO:1990778)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.4	9.9	GO:0001940	male pronucleus(GO:0001940)
1.2	12.9	GO:0005642	annulate lamellae(GO:0005642)
0.8	4.2	GO:0044615	nuclear pore nuclear basket(GO:0044615)
0.8	19.5	GO:0030285	integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.8	11.5	GO:0042788	polysomal ribosome(GO:0042788)
0.7	6.4	GO:0072687	meiotic spindle(GO:0072687)
0.6	11.2	GO:0031616	spindle pole centrosome(GO:0031616)
0.5	2.0	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.4	5.5	GO:0005640	nuclear outer membrane(GO:0005640)
0.3	12.7	GO:0008180	COP9 signalosome(GO:0008180)
0.2	2.9	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.2	1.7	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
0.2	5.6	GO:0005721	pericentric heterochromatin(GO:0005721)
0.2	4.2	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.1	2.2	GO:0042555	MCM complex(GO:0042555)
0.1	2.6	GO:0097470	ribbon synapse(GO:0097470)
0.1	7.0	GO:0005876	spindle microtubule(GO:0005876)
0.1	1.0	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.1	1.4	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1	4.7	GO:0005801	cis-Golgi network(GO:0005801)
0.1	7.8	GO:0005814	centriole(GO:0005814)
0.1	5.8	GO:0005902	microvillus(GO:0005902)
0.1	3.1	GO:0043034	costamere(GO:0043034)
0.1	5.3	GO:0030864	cortical actin cytoskeleton(GO:0030864)
0.0	1.3	GO:0005746	mitochondrial respiratory chain(GO:0005746)
0.0	0.3	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0	7.2	GO:0005667	transcription factor complex(GO:0005667)
0.0	1.1	GO:0001669	acrosomal vesicle(GO:0001669)
0.0	1.1	GO:0016323	basolateral plasma membrane(GO:0016323)
0.0	1.7	GO:0005923	bicellular tight junction(GO:0005923)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
5.2	15.7	GO:0042936	dipeptide transporter activity(GO:0042936)
2.5	12.7	GO:0043532	angiostatin binding(GO:0043532)
1.3	12.9	GO:0005049	nuclear export signal receptor activity(GO:0005049)
1.0	19.5	GO:0005313	L-glutamate transmembrane transporter activity(GO:0005313)
0.9	3.8	GO:0015410	manganese-transporting ATPase activity(GO:0015410)
0.9	3.8	GO:0035800	deubiquitinase activator activity(GO:0035800)
0.8	4.2	GO:0004032	alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.8	6.2	GO:0070739	protein-glutamic acid ligase activity(GO:0070739)
0.7	9.3	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.6	3.4	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.5	5.3	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.5	1.0	GO:0035673	oligopeptide transmembrane transporter activity(GO:0035673)
0.5	7.0	GO:0035173	histone kinase activity(GO:0035173)
0.5	3.7	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
0.4	5.5	GO:0043495	protein anchor(GO:0043495)
0.3	1.7	GO:0034604	pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.3	2.6	GO:0016618	hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.3	2.5	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.3	11.5	GO:0017091	AU-rich element binding(GO:0017091)
0.2	11.2	GO:0070888	E-box binding(GO:0070888)
0.2	9.9	GO:0097472	cyclin-dependent protein kinase activity(GO:0097472)
0.2	1.1	GO:0004322	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.2	0.6	GO:0003996	acyl-CoA ligase activity(GO:0003996)
0.2	4.2	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
0.2	2.9	GO:0016671	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.1	1.8	GO:0022889	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1	2.7	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.1	1.4	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1	1.3	GO:1990247	N6-methyladenosine-containing RNA binding(GO:1990247)
0.1	1.9	GO:0030247	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1	4.2	GO:0032452	histone demethylase activity(GO:0032452)
0.1	1.7	GO:0005521	lamin binding(GO:0005521)
0.1	13.5	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1	1.3	GO:0004129	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0	1.8	GO:0018024	histone-lysine N-methyltransferase activity(GO:0018024)
0.0	0.9	GO:0030215	semaphorin receptor binding(GO:0030215)
0.0	6.4	GO:0004386	helicase activity(GO:0004386)
0.0	2.1	GO:0005179	hormone activity(GO:0005179)
0.0	6.0	GO:0004721	phosphoprotein phosphatase activity(GO:0004721)
0.0	4.9	GO:0042393	histone binding(GO:0042393)
0.0	0.9	GO:0019213	deacetylase activity(GO:0019213)
0.0	3.1	GO:0051015	actin filament binding(GO:0051015)
0.0	1.1	GO:0019905	syntaxin binding(GO:0019905)
0.0	1.2	GO:0048365	Rac GTPase binding(GO:0048365)
0.0	7.3	GO:0005509	calcium ion binding(GO:0005509)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	7.0	SA_G2_AND_M_PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.7	9.9	SA_REG_CASCADE_OF_CYCLIN_EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.6	11.1	PID_RANBP2_PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.3	11.2	PID_AURORA_A_PATHWAY	Aurora A signaling
0.2	11.2	PID_ILK_PATHWAY	Integrin-linked kinase signaling
0.1	7.0	PID_HNF3A_PATHWAY	FOXA1 transcription factor network
0.1	5.6	PID_DELTA_NP63_PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.1	6.4	PID_PLK1_PATHWAY	PLK1 signaling events
0.1	7.1	PID_E2F_PATHWAY	E2F transcription factor network
0.1	5.3	PID_THROMBIN_PAR1_PATHWAY	PAR1-mediated thrombin signaling events
0.1	2.7	PID_RETINOIC_ACID_PATHWAY	Retinoic acid receptors-mediated signaling
0.1	2.1	PID_ANGIOPOIETIN_RECEPTOR_PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.1	2.9	ST_T_CELL_SIGNAL_TRANSDUCTION	T Cell Signal Transduction
0.0	1.7	ST_JNK_MAPK_PATHWAY	JNK MAPK Pathway
0.0	1.8	PID_P53_REGULATION_PATHWAY	p53 pathway
0.0	2.6	WNT_SIGNALING	Genes related to Wnt-mediated signal transduction
0.0	1.1	PID_AR_PATHWAY	Coregulation of Androgen receptor activity

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.8	29.8	REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.5	30.5	REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.4	7.0	REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.4	12.7	REACTOME_SIGNALING_BY_HIPPO	Genes involved in Signaling by Hippo
0.3	2.0	REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.2	9.3	REACTOME_G1_PHASE	Genes involved in G1 Phase
0.2	3.8	REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.2	3.7	REACTOME_SULFUR_AMINO_ACID_METABOLISM	Genes involved in Sulfur amino acid metabolism
0.1	4.2	REACTOME_NEP_NS2_INTERACTS_WITH_THE_CELLULAR_EXPORT_MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.1	1.7	REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1	3.8	REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES	Genes involved in Ion transport by P-type ATPases
0.1	1.2	REACTOME_ACTIVATION_OF_RAC	Genes involved in Activation of Rac
0.1	0.9	REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.1	1.4	REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	1.1	REACTOME_METAL_ION_SLC_TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.0	0.9	REACTOME_OTHER_SEMAPHORIN_INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	2.0	REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK	Genes involved in NRAGE signals death through JNK
0.0	1.3	REACTOME_RESPIRATORY_ELECTRON_TRANSPORT	Genes involved in Respiratory electron transport

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