Motif ID: Pou3f3

Z-value: 0.223


Transcription factors associated with Pou3f3:

Gene SymbolEntrez IDGene Name
Pou3f3 ENSMUSG00000045515.2 Pou3f3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pou3f3mm10_v2_chr1_+_42697146_42697146-0.065.8e-01Click!


Activity profile for motif Pou3f3.

activity profile for motif Pou3f3


Sorted Z-values histogram for motif Pou3f3

Sorted Z-values for motif Pou3f3



Network of associatons between targets according to the STRING database.



First level regulatory network of Pou3f3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_+_26331150 1.242 ENSMUST00000099182.2
 A830092H15Rik
RIKEN cDNA A830092H15 gene
chr13_-_83729544 1.062 ENSMUST00000181705.1
 Gm26803
predicted gene, 26803
chr4_+_101986626 0.966 ENSMUST00000106914.1
 Gm12789
predicted gene 12789
chr15_-_84065329 0.747 ENSMUST00000156187.1
 Efcab6
EF-hand calcium binding domain 6
chr6_+_96115249 0.729 ENSMUST00000075080.5
 Fam19a1
family with sequence similarity 19, member A1
chr17_-_50094277 0.624 ENSMUST00000113195.1
 Rftn1
raftlin lipid raft linker 1
chr6_+_17463749 0.543 ENSMUST00000115443.1
 Met
met proto-oncogene
chr5_+_66676098 0.520 ENSMUST00000031131.9
 Uchl1
ubiquitin carboxy-terminal hydrolase L1
chr18_-_33463615 0.496 ENSMUST00000051087.8
 Nrep
neuronal regeneration related protein
chr13_+_63014934 0.407 ENSMUST00000091560.4
 2010111I01Rik
RIKEN cDNA 2010111I01 gene
chr3_+_83766300 0.313 ENSMUST00000029625.7
 Sfrp2
secreted frizzled-related protein 2
chr8_-_105295934 0.302 ENSMUST00000057855.3
 Exoc3l
exocyst complex component 3-like
chr2_+_164823001 0.275 ENSMUST00000132282.1
 Zswim1
zinc finger SWIM-type containing 1
chr5_-_66514815 0.259 ENSMUST00000161879.1
ENSMUST00000159357.1
 Apbb2

amyloid beta (A4) precursor protein-binding, family B, member 2

chr13_+_72628831 0.225 ENSMUST00000169028.1
 Irx2
Iroquois related homeobox 2 (Drosophila)
chr11_-_61579637 0.207 ENSMUST00000147501.1
ENSMUST00000146455.1
ENSMUST00000108711.1
ENSMUST00000108712.1
ENSMUST00000001063.8
ENSMUST00000108713.1
ENSMUST00000179936.1
ENSMUST00000178202.1
 Epn2







epsin 2







chr2_-_154372702 0.139 ENSMUST00000028990.3
ENSMUST00000109730.2
 Cdk5rap1

CDK5 regulatory subunit associated protein 1

chrX_+_150594420 0.123 ENSMUST00000112713.2
 Pfkfb1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr2_-_30359278 0.119 ENSMUST00000163668.2
ENSMUST00000028214.8
ENSMUST00000113621.3
 Sh3glb2


SH3-domain GRB2-like endophilin B2


chr13_+_63015167 0.118 ENSMUST00000021911.8
 2010111I01Rik
RIKEN cDNA 2010111I01 gene
chr2_-_30359190 0.086 ENSMUST00000100215.4
ENSMUST00000113620.3
 Sh3glb2

SH3-domain GRB2-like endophilin B2

chr1_+_34160253 0.064 ENSMUST00000183302.1
 Dst
dystonin
chr4_-_149137536 0.031 ENSMUST00000176124.1
ENSMUST00000177408.1
ENSMUST00000105695.1
ENSMUST00000030813.3
 Apitd1



apoptosis-inducing, TAF9-like domain 1



chr3_-_146108047 0.009 ENSMUST00000160285.1
 Wdr63
WD repeat domain 63
chr7_-_126792469 0.007 ENSMUST00000032936.6
 Ppp4c
protein phosphatase 4, catalytic subunit
chr11_+_88294043 0.003 ENSMUST00000037268.4
 1700106J16Rik
RIKEN cDNA 1700106J16 gene

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0007412 axon target recognition(GO:0007412)
0.1 0.6 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.1 0.3 GO:1904956 dermatome development(GO:0061054) sclerotome development(GO:0061056) regulation of dermatome development(GO:0061183) regulation of midbrain dopaminergic neuron differentiation(GO:1904956) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.1 0.5 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.1 0.2 GO:0072272 proximal/distal pattern formation involved in metanephric nephron development(GO:0072272)
0.0 0.1 GO:1900864 positive regulation of translational fidelity(GO:0045903) mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.0 0.3 GO:0051601 exocyst localization(GO:0051601)
0.0 0.5 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.0 0.1 GO:0031673 H zone(GO:0031673)
0.0 0.3 GO:0000145 exocyst(GO:0000145)
0.0 0.2 GO:0030128 clathrin coat of endocytic vesicle(GO:0030128) clathrin-coated endocytic vesicle membrane(GO:0030669)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.1 0.5 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.0 0.3 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.5 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.1 GO:0070095 fructose-6-phosphate binding(GO:0070095)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.0 0.5 PID_ARF6_PATHWAY Arf6 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING Genes involved in Sema4D in semaphorin signaling