Motif ID: Pparg_Rxrg
Z-value: 1.842
Transcription factors associated with Pparg_Rxrg:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Pparg | ENSMUSG00000000440.6 | Pparg |
| Rxrg | ENSMUSG00000015843.4 | Rxrg |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Rxrg | mm10_v2_chr1_+_167598384_167598411 | 0.15 | 2.0e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 13.1 | 39.4 | GO:0006553 | lysine metabolic process(GO:0006553) |
| 6.1 | 24.5 | GO:1902724 | positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728) |
| 4.6 | 18.5 | GO:0060729 | intestinal epithelial structure maintenance(GO:0060729) |
| 4.2 | 12.7 | GO:0006601 | creatine biosynthetic process(GO:0006601) |
| 4.2 | 37.9 | GO:0033314 | mitotic DNA replication checkpoint(GO:0033314) |
| 4.0 | 16.1 | GO:0035609 | C-terminal protein deglutamylation(GO:0035609) |
| 4.0 | 71.6 | GO:0033539 | fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539) |
| 3.9 | 11.7 | GO:0097089 | methyl-branched fatty acid metabolic process(GO:0097089) |
| 3.8 | 11.4 | GO:0003162 | atrioventricular node development(GO:0003162) |
| 3.3 | 16.7 | GO:0035262 | gonad morphogenesis(GO:0035262) |
| 3.3 | 23.2 | GO:2001199 | negative regulation of dendritic cell differentiation(GO:2001199) |
| 3.2 | 12.6 | GO:2001045 | closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045) |
| 3.1 | 9.4 | GO:0051754 | meiotic sister chromatid cohesion, centromeric(GO:0051754) |
| 3.1 | 15.6 | GO:0032901 | positive regulation of neurotrophin production(GO:0032901) |
| 3.1 | 9.3 | GO:0070315 | G1 to G0 transition involved in cell differentiation(GO:0070315) |
| 3.1 | 9.2 | GO:0090274 | positive regulation of somatostatin secretion(GO:0090274) |
| 3.0 | 8.9 | GO:0019074 | viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074) |
| 2.9 | 8.7 | GO:0045004 | DNA replication proofreading(GO:0045004) |
| 2.5 | 22.9 | GO:0071493 | cellular response to UV-B(GO:0071493) |
| 2.4 | 7.2 | GO:0016095 | polyprenol catabolic process(GO:0016095) terpenoid catabolic process(GO:0016115) primary alcohol catabolic process(GO:0034310) |
| 2.3 | 7.0 | GO:0003360 | brainstem development(GO:0003360) |
| 2.3 | 18.2 | GO:0016576 | histone dephosphorylation(GO:0016576) |
| 2.2 | 8.6 | GO:0030997 | regulation of centriole-centriole cohesion(GO:0030997) |
| 2.1 | 6.3 | GO:0032918 | polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918) |
| 2.1 | 2.1 | GO:0061324 | canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) |
| 2.0 | 8.0 | GO:0021698 | cerebellar cortex structural organization(GO:0021698) |
| 2.0 | 11.9 | GO:0032483 | regulation of Rab protein signal transduction(GO:0032483) |
| 1.9 | 15.4 | GO:0035542 | regulation of SNARE complex assembly(GO:0035542) |
| 1.9 | 5.7 | GO:2001187 | natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187) |
| 1.8 | 18.4 | GO:0031119 | tRNA pseudouridine synthesis(GO:0031119) |
| 1.8 | 5.4 | GO:0060084 | synaptic transmission involved in micturition(GO:0060084) |
| 1.8 | 5.4 | GO:0019676 | ammonia assimilation cycle(GO:0019676) |
| 1.8 | 17.8 | GO:0042573 | retinoic acid metabolic process(GO:0042573) |
| 1.8 | 5.3 | GO:0002678 | positive regulation of chronic inflammatory response(GO:0002678) |
| 1.8 | 10.6 | GO:2000483 | detection of bacterium(GO:0016045) detection of other organism(GO:0098543) negative regulation of interleukin-8 secretion(GO:2000483) |
| 1.7 | 6.9 | GO:0019355 | nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628) |
| 1.7 | 29.3 | GO:0051988 | regulation of attachment of spindle microtubules to kinetochore(GO:0051988) |
| 1.7 | 16.6 | GO:1901386 | negative regulation of voltage-gated calcium channel activity(GO:1901386) |
| 1.5 | 6.0 | GO:0006145 | purine nucleobase catabolic process(GO:0006145) |
| 1.5 | 4.5 | GO:0036500 | ATF6-mediated unfolded protein response(GO:0036500) |
| 1.4 | 5.6 | GO:1904778 | regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778) |
| 1.4 | 4.2 | GO:1904211 | membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211) |
| 1.4 | 6.8 | GO:1904684 | negative regulation of metalloendopeptidase activity(GO:1904684) |
| 1.3 | 4.0 | GO:0072734 | response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734) |
| 1.3 | 5.3 | GO:0042414 | epinephrine metabolic process(GO:0042414) |
| 1.3 | 3.9 | GO:0007228 | positive regulation of hh target transcription factor activity(GO:0007228) |
| 1.3 | 3.8 | GO:0070779 | D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779) |
| 1.2 | 7.4 | GO:0032229 | positive regulation of gamma-aminobutyric acid secretion(GO:0014054) negative regulation of synaptic transmission, GABAergic(GO:0032229) |
| 1.2 | 3.6 | GO:0097500 | receptor localization to nonmotile primary cilium(GO:0097500) |
| 1.2 | 9.4 | GO:0045656 | negative regulation of monocyte differentiation(GO:0045656) |
| 1.2 | 4.7 | GO:0010510 | regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) |
| 1.1 | 7.7 | GO:0032596 | protein transport into membrane raft(GO:0032596) |
| 1.1 | 7.6 | GO:0071294 | cellular response to zinc ion(GO:0071294) |
| 1.1 | 6.5 | GO:0045743 | positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743) |
| 1.0 | 5.2 | GO:1903215 | negative regulation of protein targeting to mitochondrion(GO:1903215) |
| 1.0 | 5.1 | GO:0048682 | axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682) |
| 1.0 | 7.1 | GO:0060372 | regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372) |
| 1.0 | 3.0 | GO:0014809 | regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809) |
| 1.0 | 6.8 | GO:0051151 | negative regulation of smooth muscle cell differentiation(GO:0051151) |
| 1.0 | 4.8 | GO:0034196 | acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197) |
| 0.9 | 4.6 | GO:0036151 | phosphatidylcholine acyl-chain remodeling(GO:0036151) |
| 0.9 | 8.3 | GO:1902715 | positive regulation of interferon-gamma secretion(GO:1902715) |
| 0.9 | 3.7 | GO:0002337 | B-1a B cell differentiation(GO:0002337) |
| 0.9 | 3.6 | GO:2000048 | negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048) |
| 0.9 | 3.6 | GO:0035937 | estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864) |
| 0.9 | 2.6 | GO:1901896 | positive regulation of calcium-transporting ATPase activity(GO:1901896) |
| 0.8 | 1.7 | GO:0042940 | D-amino acid transport(GO:0042940) |
| 0.8 | 5.0 | GO:0032196 | regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529) transposition(GO:0032196) |
| 0.8 | 2.5 | GO:1900108 | negative regulation of nodal signaling pathway(GO:1900108) |
| 0.8 | 1.6 | GO:0034382 | chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830) |
| 0.8 | 0.8 | GO:0060455 | negative regulation of gastric acid secretion(GO:0060455) |
| 0.8 | 5.6 | GO:0007296 | vitellogenesis(GO:0007296) |
| 0.8 | 4.8 | GO:0032929 | negative regulation of superoxide anion generation(GO:0032929) |
| 0.8 | 3.9 | GO:1903232 | melanosome assembly(GO:1903232) |
| 0.8 | 8.7 | GO:0060575 | intestinal epithelial cell differentiation(GO:0060575) |
| 0.8 | 1.5 | GO:0002489 | antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489) |
| 0.7 | 3.0 | GO:1901668 | regulation of superoxide dismutase activity(GO:1901668) |
| 0.7 | 32.7 | GO:1902476 | chloride transmembrane transport(GO:1902476) |
| 0.7 | 2.9 | GO:2001185 | regulation of CD8-positive, alpha-beta T cell activation(GO:2001185) |
| 0.7 | 8.0 | GO:2001269 | positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269) |
| 0.7 | 8.0 | GO:0019368 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
| 0.7 | 5.7 | GO:0007016 | cytoskeletal anchoring at plasma membrane(GO:0007016) |
| 0.7 | 4.3 | GO:0000098 | sulfur amino acid catabolic process(GO:0000098) |
| 0.7 | 11.9 | GO:0030574 | collagen catabolic process(GO:0030574) |
| 0.7 | 4.8 | GO:0001773 | myeloid dendritic cell activation(GO:0001773) myeloid dendritic cell differentiation(GO:0043011) |
| 0.7 | 2.1 | GO:2000620 | positive regulation of histone H4-K16 acetylation(GO:2000620) |
| 0.7 | 2.7 | GO:0071475 | cellular hyperosmotic salinity response(GO:0071475) negative regulation of t-circle formation(GO:1904430) |
| 0.7 | 4.8 | GO:0060903 | positive regulation of meiosis I(GO:0060903) |
| 0.7 | 3.3 | GO:0035022 | positive regulation of Rac protein signal transduction(GO:0035022) |
| 0.6 | 3.2 | GO:0015671 | oxygen transport(GO:0015671) |
| 0.6 | 0.6 | GO:0039519 | modulation by virus of host autophagy(GO:0039519) |
| 0.6 | 1.3 | GO:2000157 | regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157) |
| 0.6 | 1.9 | GO:0071072 | negative regulation of phospholipid biosynthetic process(GO:0071072) |
| 0.6 | 10.2 | GO:0048368 | lateral mesoderm development(GO:0048368) |
| 0.6 | 5.1 | GO:0051231 | mitotic spindle elongation(GO:0000022) spindle elongation(GO:0051231) mitotic spindle midzone assembly(GO:0051256) |
| 0.6 | 3.7 | GO:1901072 | glucosamine-containing compound catabolic process(GO:1901072) |
| 0.6 | 6.7 | GO:0032494 | response to peptidoglycan(GO:0032494) |
| 0.6 | 1.8 | GO:1903048 | regulation of acetylcholine-gated cation channel activity(GO:1903048) |
| 0.6 | 4.1 | GO:1904217 | regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222) |
| 0.6 | 5.9 | GO:0060059 | embryonic retina morphogenesis in camera-type eye(GO:0060059) |
| 0.6 | 6.4 | GO:0034501 | protein localization to kinetochore(GO:0034501) |
| 0.6 | 6.3 | GO:1903818 | positive regulation of voltage-gated potassium channel activity(GO:1903818) |
| 0.6 | 1.7 | GO:0014063 | negative regulation of serotonin secretion(GO:0014063) |
| 0.6 | 4.0 | GO:0033567 | DNA replication, Okazaki fragment processing(GO:0033567) |
| 0.6 | 1.7 | GO:0060129 | thyroid-stimulating hormone-secreting cell differentiation(GO:0060129) |
| 0.6 | 2.8 | GO:0090272 | negative regulation of fibroblast growth factor production(GO:0090272) |
| 0.6 | 2.8 | GO:1990839 | response to endothelin(GO:1990839) |
| 0.5 | 3.8 | GO:0035701 | hematopoietic stem cell migration(GO:0035701) |
| 0.5 | 2.7 | GO:2000680 | regulation of rubidium ion transport(GO:2000680) |
| 0.5 | 6.4 | GO:0046643 | regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643) |
| 0.5 | 2.1 | GO:1903265 | positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265) |
| 0.5 | 1.5 | GO:0035964 | COPI-coated vesicle budding(GO:0035964) |
| 0.5 | 1.5 | GO:0015920 | lipopolysaccharide transport(GO:0015920) |
| 0.5 | 4.0 | GO:0038030 | non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030) non-canonical Wnt signaling pathway via JNK cascade(GO:0038031) |
| 0.5 | 1.9 | GO:0060020 | Bergmann glial cell differentiation(GO:0060020) |
| 0.5 | 5.8 | GO:0009404 | toxin metabolic process(GO:0009404) |
| 0.5 | 2.9 | GO:0006703 | estrogen biosynthetic process(GO:0006703) |
| 0.5 | 2.9 | GO:0006172 | ADP biosynthetic process(GO:0006172) |
| 0.5 | 5.7 | GO:2000507 | positive regulation of energy homeostasis(GO:2000507) |
| 0.5 | 1.4 | GO:0019405 | alditol catabolic process(GO:0019405) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166) |
| 0.5 | 2.9 | GO:0046826 | negative regulation of protein export from nucleus(GO:0046826) |
| 0.5 | 23.2 | GO:0015914 | phospholipid transport(GO:0015914) |
| 0.5 | 2.3 | GO:0030240 | skeletal muscle thin filament assembly(GO:0030240) |
| 0.4 | 1.3 | GO:0006669 | sphinganine-1-phosphate biosynthetic process(GO:0006669) |
| 0.4 | 1.8 | GO:0002072 | optic cup morphogenesis involved in camera-type eye development(GO:0002072) |
| 0.4 | 5.3 | GO:0007250 | activation of NF-kappaB-inducing kinase activity(GO:0007250) |
| 0.4 | 1.3 | GO:0001928 | regulation of exocyst assembly(GO:0001928) |
| 0.4 | 2.1 | GO:0034379 | very-low-density lipoprotein particle assembly(GO:0034379) |
| 0.4 | 4.2 | GO:1901409 | positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409) |
| 0.4 | 1.7 | GO:0046726 | positive regulation by virus of viral protein levels in host cell(GO:0046726) |
| 0.4 | 1.7 | GO:0055071 | cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071) |
| 0.4 | 1.7 | GO:0042373 | vitamin K metabolic process(GO:0042373) |
| 0.4 | 2.5 | GO:0098734 | protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734) |
| 0.4 | 1.6 | GO:0035752 | lysosomal lumen pH elevation(GO:0035752) |
| 0.4 | 3.2 | GO:0071557 | histone H3-K27 demethylation(GO:0071557) |
| 0.4 | 1.6 | GO:0015793 | glycerol transport(GO:0015793) |
| 0.4 | 9.3 | GO:0030866 | cortical actin cytoskeleton organization(GO:0030866) |
| 0.4 | 18.3 | GO:0043001 | Golgi to plasma membrane protein transport(GO:0043001) |
| 0.4 | 1.1 | GO:0021577 | hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589) |
| 0.4 | 1.5 | GO:2000562 | negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562) |
| 0.4 | 1.9 | GO:0071500 | cellular response to nitrosative stress(GO:0071500) |
| 0.4 | 1.5 | GO:0060907 | positive regulation of macrophage cytokine production(GO:0060907) |
| 0.4 | 1.5 | GO:2000192 | negative regulation of fatty acid transport(GO:2000192) |
| 0.4 | 1.1 | GO:2000018 | regulation of male gonad development(GO:2000018) positive regulation of male gonad development(GO:2000020) |
| 0.4 | 3.0 | GO:1903003 | positive regulation of protein deubiquitination(GO:1903003) |
| 0.4 | 7.4 | GO:0006353 | DNA-templated transcription, termination(GO:0006353) |
| 0.4 | 5.4 | GO:2001275 | positive regulation of glucose import in response to insulin stimulus(GO:2001275) |
| 0.4 | 3.3 | GO:1903351 | response to dopamine(GO:1903350) cellular response to dopamine(GO:1903351) |
| 0.4 | 1.1 | GO:0071963 | establishment or maintenance of cell polarity regulating cell shape(GO:0071963) |
| 0.4 | 0.7 | GO:0070309 | lens fiber cell morphogenesis(GO:0070309) |
| 0.4 | 3.2 | GO:1900364 | negative regulation of mRNA polyadenylation(GO:1900364) |
| 0.3 | 1.0 | GO:0032020 | ISG15-protein conjugation(GO:0032020) |
| 0.3 | 15.9 | GO:0035411 | catenin import into nucleus(GO:0035411) |
| 0.3 | 2.7 | GO:0048386 | positive regulation of retinoic acid receptor signaling pathway(GO:0048386) |
| 0.3 | 2.4 | GO:0030242 | pexophagy(GO:0030242) |
| 0.3 | 14.7 | GO:2001222 | regulation of neuron migration(GO:2001222) |
| 0.3 | 3.3 | GO:0021869 | forebrain ventricular zone progenitor cell division(GO:0021869) |
| 0.3 | 1.3 | GO:1903966 | monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966) |
| 0.3 | 1.0 | GO:0042732 | D-xylose metabolic process(GO:0042732) |
| 0.3 | 3.2 | GO:0046339 | diacylglycerol metabolic process(GO:0046339) |
| 0.3 | 4.5 | GO:0071257 | cellular response to electrical stimulus(GO:0071257) |
| 0.3 | 1.9 | GO:0006957 | complement activation, alternative pathway(GO:0006957) |
| 0.3 | 4.2 | GO:0019363 | pyridine nucleotide biosynthetic process(GO:0019363) |
| 0.3 | 1.6 | GO:1904690 | regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690) |
| 0.3 | 2.9 | GO:0048312 | intracellular distribution of mitochondria(GO:0048312) |
| 0.3 | 1.3 | GO:0021882 | regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898) |
| 0.3 | 1.2 | GO:2000252 | negative regulation of feeding behavior(GO:2000252) |
| 0.3 | 1.2 | GO:0060800 | regulation of cell differentiation involved in embryonic placenta development(GO:0060800) |
| 0.3 | 3.4 | GO:0007141 | male meiosis I(GO:0007141) |
| 0.3 | 1.8 | GO:1903071 | positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071) |
| 0.3 | 0.6 | GO:0090086 | negative regulation of protein deubiquitination(GO:0090086) |
| 0.3 | 9.1 | GO:0031116 | positive regulation of microtubule polymerization(GO:0031116) |
| 0.3 | 2.7 | GO:0045579 | positive regulation of B cell differentiation(GO:0045579) |
| 0.3 | 6.3 | GO:0071392 | cellular response to estradiol stimulus(GO:0071392) |
| 0.3 | 19.2 | GO:0008156 | negative regulation of DNA replication(GO:0008156) |
| 0.3 | 3.0 | GO:0030388 | fructose 1,6-bisphosphate metabolic process(GO:0030388) |
| 0.3 | 2.4 | GO:0070940 | dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940) |
| 0.3 | 0.9 | GO:0002175 | protein localization to paranode region of axon(GO:0002175) |
| 0.3 | 5.0 | GO:0030220 | platelet formation(GO:0030220) |
| 0.3 | 4.4 | GO:0046855 | inositol phosphate dephosphorylation(GO:0046855) |
| 0.3 | 1.2 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
| 0.3 | 7.3 | GO:0032292 | myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292) |
| 0.3 | 4.0 | GO:0045603 | positive regulation of endothelial cell differentiation(GO:0045603) |
| 0.3 | 2.3 | GO:0007216 | G-protein coupled glutamate receptor signaling pathway(GO:0007216) |
| 0.3 | 2.5 | GO:0010866 | regulation of triglyceride biosynthetic process(GO:0010866) |
| 0.3 | 1.1 | GO:0051152 | positive regulation of smooth muscle cell differentiation(GO:0051152) |
| 0.3 | 2.7 | GO:0008298 | intracellular mRNA localization(GO:0008298) |
| 0.3 | 0.3 | GO:0097029 | mature conventional dendritic cell differentiation(GO:0097029) |
| 0.3 | 0.5 | GO:1902166 | negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166) |
| 0.3 | 4.3 | GO:0045947 | negative regulation of translational initiation(GO:0045947) |
| 0.3 | 0.3 | GO:1902953 | positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953) |
| 0.3 | 8.0 | GO:0060351 | cartilage development involved in endochondral bone morphogenesis(GO:0060351) |
| 0.3 | 1.6 | GO:0060539 | diaphragm development(GO:0060539) |
| 0.3 | 7.7 | GO:0034508 | centromere complex assembly(GO:0034508) |
| 0.3 | 1.1 | GO:1990022 | RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022) |
| 0.3 | 1.1 | GO:0003365 | establishment of cell polarity involved in ameboidal cell migration(GO:0003365) |
| 0.3 | 0.8 | GO:0045819 | plasmacytoid dendritic cell activation(GO:0002270) positive regulation of glycogen catabolic process(GO:0045819) |
| 0.3 | 1.0 | GO:0006014 | D-ribose metabolic process(GO:0006014) |
| 0.3 | 1.0 | GO:0060290 | transdifferentiation(GO:0060290) |
| 0.3 | 8.9 | GO:0048025 | negative regulation of mRNA splicing, via spliceosome(GO:0048025) |
| 0.3 | 8.5 | GO:0050853 | B cell receptor signaling pathway(GO:0050853) |
| 0.3 | 2.8 | GO:1904262 | negative regulation of TORC1 signaling(GO:1904262) |
| 0.3 | 10.3 | GO:0035307 | positive regulation of protein dephosphorylation(GO:0035307) |
| 0.2 | 0.7 | GO:1902605 | heterotrimeric G-protein complex assembly(GO:1902605) |
| 0.2 | 2.7 | GO:0046784 | viral mRNA export from host cell nucleus(GO:0046784) |
| 0.2 | 8.3 | GO:0007588 | excretion(GO:0007588) |
| 0.2 | 1.0 | GO:0060406 | positive regulation of penile erection(GO:0060406) |
| 0.2 | 0.5 | GO:0002484 | antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway(GO:0002484) antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent(GO:0002485) |
| 0.2 | 0.7 | GO:1903363 | negative regulation of cellular protein catabolic process(GO:1903363) |
| 0.2 | 4.4 | GO:0001967 | suckling behavior(GO:0001967) |
| 0.2 | 1.1 | GO:0071947 | protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947) |
| 0.2 | 7.9 | GO:0045746 | negative regulation of Notch signaling pathway(GO:0045746) |
| 0.2 | 1.8 | GO:0007020 | microtubule nucleation(GO:0007020) |
| 0.2 | 2.0 | GO:2001238 | positive regulation of extrinsic apoptotic signaling pathway(GO:2001238) |
| 0.2 | 6.6 | GO:0015909 | long-chain fatty acid transport(GO:0015909) |
| 0.2 | 1.9 | GO:0018095 | protein polyglutamylation(GO:0018095) |
| 0.2 | 1.1 | GO:0060279 | positive regulation of ovulation(GO:0060279) |
| 0.2 | 0.6 | GO:0021631 | optic nerve morphogenesis(GO:0021631) |
| 0.2 | 2.8 | GO:1902187 | negative regulation of viral release from host cell(GO:1902187) |
| 0.2 | 0.8 | GO:0090309 | positive regulation of methylation-dependent chromatin silencing(GO:0090309) |
| 0.2 | 2.5 | GO:0050901 | leukocyte tethering or rolling(GO:0050901) |
| 0.2 | 1.6 | GO:1900194 | receptor guanylyl cyclase signaling pathway(GO:0007168) negative regulation of oocyte maturation(GO:1900194) |
| 0.2 | 1.6 | GO:0007252 | I-kappaB phosphorylation(GO:0007252) |
| 0.2 | 0.6 | GO:0090285 | negative regulation of protein glycosylation in Golgi(GO:0090285) |
| 0.2 | 4.9 | GO:0050873 | brown fat cell differentiation(GO:0050873) |
| 0.2 | 4.7 | GO:0071300 | cellular response to retinoic acid(GO:0071300) |
| 0.2 | 0.8 | GO:0009212 | dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) dTTP metabolic process(GO:0046075) |
| 0.2 | 0.8 | GO:0098902 | regulation of membrane depolarization during action potential(GO:0098902) regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900825) |
| 0.2 | 0.8 | GO:0046604 | positive regulation of mitotic centrosome separation(GO:0046604) |
| 0.2 | 0.4 | GO:1905049 | negative regulation of metallopeptidase activity(GO:1905049) |
| 0.2 | 4.1 | GO:0048026 | positive regulation of mRNA splicing, via spliceosome(GO:0048026) |
| 0.2 | 3.2 | GO:0043486 | histone exchange(GO:0043486) |
| 0.2 | 1.8 | GO:0090344 | negative regulation of cell aging(GO:0090344) |
| 0.2 | 2.0 | GO:0050892 | intestinal absorption(GO:0050892) |
| 0.2 | 4.6 | GO:0000289 | nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289) |
| 0.2 | 1.4 | GO:1902231 | positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231) |
| 0.2 | 1.8 | GO:0060259 | regulation of feeding behavior(GO:0060259) |
| 0.2 | 0.5 | GO:0045925 | positive regulation of female receptivity(GO:0045925) |
| 0.2 | 0.7 | GO:0010224 | response to UV-B(GO:0010224) |
| 0.2 | 10.7 | GO:0032092 | positive regulation of protein binding(GO:0032092) |
| 0.2 | 4.6 | GO:0018345 | protein palmitoylation(GO:0018345) |
| 0.2 | 0.3 | GO:1903961 | positive regulation of anion transmembrane transport(GO:1903961) |
| 0.2 | 2.4 | GO:0061029 | eyelid development in camera-type eye(GO:0061029) |
| 0.2 | 2.7 | GO:0010758 | regulation of macrophage chemotaxis(GO:0010758) |
| 0.2 | 0.8 | GO:0019885 | antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885) |
| 0.2 | 0.5 | GO:2000858 | mineralocorticoid secretion(GO:0035931) aldosterone secretion(GO:0035932) regulation of mineralocorticoid secretion(GO:2000855) positive regulation of mineralocorticoid secretion(GO:2000857) regulation of aldosterone secretion(GO:2000858) positive regulation of aldosterone secretion(GO:2000860) |
| 0.2 | 2.5 | GO:0006893 | Golgi to plasma membrane transport(GO:0006893) |
| 0.2 | 0.8 | GO:0061718 | NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718) |
| 0.2 | 3.6 | GO:0045669 | positive regulation of osteoblast differentiation(GO:0045669) |
| 0.2 | 0.6 | GO:0060690 | epithelial cell differentiation involved in salivary gland development(GO:0060690) |
| 0.2 | 6.7 | GO:0050830 | defense response to Gram-positive bacterium(GO:0050830) |
| 0.2 | 4.2 | GO:0000132 | establishment of mitotic spindle orientation(GO:0000132) |
| 0.2 | 1.1 | GO:0051418 | interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418) |
| 0.1 | 0.7 | GO:0050912 | detection of chemical stimulus involved in sensory perception(GO:0050907) detection of chemical stimulus involved in sensory perception of taste(GO:0050912) |
| 0.1 | 3.4 | GO:0051497 | negative regulation of stress fiber assembly(GO:0051497) |
| 0.1 | 2.2 | GO:0048096 | chromatin-mediated maintenance of transcription(GO:0048096) |
| 0.1 | 1.3 | GO:0031639 | plasminogen activation(GO:0031639) |
| 0.1 | 12.9 | GO:0090090 | negative regulation of canonical Wnt signaling pathway(GO:0090090) |
| 0.1 | 0.4 | GO:0000429 | carbon catabolite regulation of transcription from RNA polymerase II promoter(GO:0000429) regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) carbon catabolite activation of transcription from RNA polymerase II promoter(GO:0000436) carbon catabolite activation of transcription(GO:0045991) positive regulation of transcription by glucose(GO:0046016) |
| 0.1 | 3.4 | GO:0006904 | vesicle docking involved in exocytosis(GO:0006904) |
| 0.1 | 0.8 | GO:0090050 | positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) |
| 0.1 | 0.3 | GO:0089700 | protein kinase D signaling(GO:0089700) |
| 0.1 | 8.1 | GO:0006749 | glutathione metabolic process(GO:0006749) |
| 0.1 | 2.5 | GO:0007271 | synaptic transmission, cholinergic(GO:0007271) |
| 0.1 | 7.7 | GO:0051489 | regulation of filopodium assembly(GO:0051489) |
| 0.1 | 1.3 | GO:0019835 | cytolysis(GO:0019835) |
| 0.1 | 3.3 | GO:0030513 | positive regulation of BMP signaling pathway(GO:0030513) |
| 0.1 | 0.4 | GO:0090205 | cell chemotaxis to fibroblast growth factor(GO:0035766) endothelial cell chemotaxis to fibroblast growth factor(GO:0035768) positive regulation of cholesterol biosynthetic process(GO:0045542) branch elongation involved in ureteric bud branching(GO:0060681) positive regulation of cholesterol metabolic process(GO:0090205) regulation of cell chemotaxis to fibroblast growth factor(GO:1904847) regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000544) |
| 0.1 | 1.5 | GO:0048642 | negative regulation of skeletal muscle tissue development(GO:0048642) |
| 0.1 | 1.4 | GO:0046622 | positive regulation of organ growth(GO:0046622) |
| 0.1 | 2.5 | GO:0090200 | positive regulation of release of cytochrome c from mitochondria(GO:0090200) |
| 0.1 | 2.2 | GO:0043551 | regulation of phosphatidylinositol 3-kinase activity(GO:0043551) |
| 0.1 | 0.4 | GO:0006436 | tryptophanyl-tRNA aminoacylation(GO:0006436) |
| 0.1 | 9.2 | GO:0030177 | positive regulation of Wnt signaling pathway(GO:0030177) |
| 0.1 | 0.5 | GO:0032959 | inositol trisphosphate biosynthetic process(GO:0032959) |
| 0.1 | 0.6 | GO:0042256 | mature ribosome assembly(GO:0042256) |
| 0.1 | 1.0 | GO:0071447 | cellular response to hydroperoxide(GO:0071447) |
| 0.1 | 1.9 | GO:0043567 | regulation of insulin-like growth factor receptor signaling pathway(GO:0043567) |
| 0.1 | 0.7 | GO:1903300 | negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300) |
| 0.1 | 14.1 | GO:0007160 | cell-matrix adhesion(GO:0007160) |
| 0.1 | 0.7 | GO:0070236 | negative regulation of activation-induced cell death of T cells(GO:0070236) |
| 0.1 | 0.8 | GO:0030728 | ovulation(GO:0030728) |
| 0.1 | 1.1 | GO:0010043 | response to zinc ion(GO:0010043) |
| 0.1 | 1.1 | GO:1903504 | regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504) |
| 0.1 | 3.3 | GO:0006829 | zinc II ion transport(GO:0006829) |
| 0.1 | 6.3 | GO:0043488 | regulation of mRNA stability(GO:0043488) |
| 0.1 | 0.6 | GO:0031953 | negative regulation of protein autophosphorylation(GO:0031953) |
| 0.1 | 0.4 | GO:0036462 | TRAIL-activated apoptotic signaling pathway(GO:0036462) |
| 0.1 | 0.5 | GO:0008655 | pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097) |
| 0.1 | 0.4 | GO:0090282 | positive regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071931) positive regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0090282) |
| 0.1 | 3.3 | GO:0045670 | regulation of osteoclast differentiation(GO:0045670) |
| 0.1 | 0.8 | GO:0016559 | peroxisome fission(GO:0016559) |
| 0.1 | 0.6 | GO:0031584 | activation of phospholipase D activity(GO:0031584) |
| 0.1 | 0.8 | GO:0007000 | nucleolus organization(GO:0007000) |
| 0.1 | 1.3 | GO:0043407 | negative regulation of MAP kinase activity(GO:0043407) |
| 0.1 | 0.9 | GO:0006450 | regulation of translational fidelity(GO:0006450) |
| 0.1 | 0.9 | GO:0000463 | maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) |
| 0.1 | 0.2 | GO:0032510 | endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510) |
| 0.1 | 2.1 | GO:0045604 | regulation of epidermal cell differentiation(GO:0045604) |
| 0.1 | 0.8 | GO:2000637 | positive regulation of gene silencing by miRNA(GO:2000637) |
| 0.1 | 2.1 | GO:0043666 | regulation of phosphoprotein phosphatase activity(GO:0043666) |
| 0.1 | 0.6 | GO:0042136 | neurotransmitter biosynthetic process(GO:0042136) |
| 0.1 | 1.0 | GO:0000729 | DNA double-strand break processing(GO:0000729) |
| 0.1 | 0.5 | GO:0006451 | selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451) |
| 0.1 | 0.8 | GO:1904294 | positive regulation of ERAD pathway(GO:1904294) |
| 0.1 | 0.4 | GO:0048227 | plasma membrane to endosome transport(GO:0048227) |
| 0.1 | 0.8 | GO:0030813 | positive regulation of nucleotide catabolic process(GO:0030813) positive regulation of glycolytic process(GO:0045821) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197) |
| 0.1 | 0.2 | GO:1903912 | regulation of translation in response to endoplasmic reticulum stress(GO:0036490) regulation of translation initiation in response to endoplasmic reticulum stress(GO:0036491) eiF2alpha phosphorylation in response to endoplasmic reticulum stress(GO:0036492) negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912) |
| 0.1 | 1.3 | GO:0045116 | protein neddylation(GO:0045116) |
| 0.1 | 1.6 | GO:0016578 | histone deubiquitination(GO:0016578) |
| 0.1 | 0.4 | GO:0015879 | carnitine transport(GO:0015879) |
| 0.1 | 0.4 | GO:0045667 | regulation of osteoblast differentiation(GO:0045667) |
| 0.1 | 2.4 | GO:0006891 | intra-Golgi vesicle-mediated transport(GO:0006891) |
| 0.1 | 0.5 | GO:0010032 | meiotic chromosome condensation(GO:0010032) |
| 0.1 | 0.5 | GO:0033119 | negative regulation of RNA splicing(GO:0033119) |
| 0.1 | 0.6 | GO:0097186 | amelogenesis(GO:0097186) |
| 0.1 | 4.1 | GO:0060021 | palate development(GO:0060021) |
| 0.1 | 0.2 | GO:0032074 | negative regulation of nuclease activity(GO:0032074) |
| 0.1 | 0.9 | GO:0050819 | negative regulation of coagulation(GO:0050819) |
| 0.1 | 0.9 | GO:0001964 | startle response(GO:0001964) |
| 0.1 | 0.6 | GO:0090141 | positive regulation of mitochondrial fission(GO:0090141) |
| 0.1 | 1.5 | GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146) |
| 0.1 | 0.9 | GO:0043968 | histone H2A acetylation(GO:0043968) |
| 0.1 | 0.3 | GO:0071985 | multivesicular body sorting pathway(GO:0071985) |
| 0.1 | 2.7 | GO:1901379 | regulation of potassium ion transmembrane transport(GO:1901379) |
| 0.1 | 0.4 | GO:0050829 | defense response to Gram-negative bacterium(GO:0050829) |
| 0.0 | 0.5 | GO:0009650 | UV protection(GO:0009650) |
| 0.0 | 0.7 | GO:0061003 | positive regulation of dendritic spine morphogenesis(GO:0061003) |
| 0.0 | 0.4 | GO:0002052 | positive regulation of neuroblast proliferation(GO:0002052) |
| 0.0 | 0.7 | GO:0014898 | muscle hypertrophy in response to stress(GO:0003299) cardiac muscle hypertrophy in response to stress(GO:0014898) |
| 0.0 | 2.4 | GO:0080171 | lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171) |
| 0.0 | 2.5 | GO:0010389 | regulation of G2/M transition of mitotic cell cycle(GO:0010389) |
| 0.0 | 0.2 | GO:2001241 | positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241) |
| 0.0 | 0.9 | GO:1990126 | retrograde transport, endosome to plasma membrane(GO:1990126) |
| 0.0 | 7.4 | GO:0007266 | Rho protein signal transduction(GO:0007266) |
| 0.0 | 0.4 | GO:2000671 | regulation of motor neuron apoptotic process(GO:2000671) |
| 0.0 | 0.7 | GO:0043248 | proteasome assembly(GO:0043248) |
| 0.0 | 0.8 | GO:0051560 | mitochondrial calcium ion homeostasis(GO:0051560) |
| 0.0 | 0.2 | GO:0046415 | urate metabolic process(GO:0046415) |
| 0.0 | 0.2 | GO:0070164 | negative regulation of adiponectin secretion(GO:0070164) |
| 0.0 | 1.6 | GO:0006505 | GPI anchor metabolic process(GO:0006505) GPI anchor biosynthetic process(GO:0006506) |
| 0.0 | 0.2 | GO:0006646 | phosphatidylethanolamine biosynthetic process(GO:0006646) |
| 0.0 | 0.4 | GO:0036075 | endochondral ossification(GO:0001958) replacement ossification(GO:0036075) endochondral bone morphogenesis(GO:0060350) |
| 0.0 | 1.5 | GO:0035914 | skeletal muscle cell differentiation(GO:0035914) |
| 0.0 | 0.1 | GO:0051099 | positive regulation of binding(GO:0051099) |
| 0.0 | 0.1 | GO:0042760 | very long-chain fatty acid catabolic process(GO:0042760) |
| 0.0 | 0.3 | GO:0098779 | mitophagy in response to mitochondrial depolarization(GO:0098779) |
| 0.0 | 0.7 | GO:0032011 | ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012) |
| 0.0 | 1.1 | GO:0006096 | glycolytic process(GO:0006096) ATP generation from ADP(GO:0006757) |
| 0.0 | 0.7 | GO:0015985 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
| 0.0 | 0.2 | GO:0008053 | mitochondrial fusion(GO:0008053) mitochondrial protein processing(GO:0034982) |
| 0.0 | 0.5 | GO:0048278 | vesicle docking(GO:0048278) |
| 0.0 | 0.0 | GO:0033364 | mast cell secretory granule organization(GO:0033364) |
| 0.0 | 0.1 | GO:0030854 | positive regulation of granulocyte differentiation(GO:0030854) |
| 0.0 | 0.5 | GO:0035335 | peptidyl-tyrosine dephosphorylation(GO:0035335) |
| 0.0 | 0.3 | GO:0097034 | mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034) |
| 0.0 | 1.1 | GO:0032006 | regulation of TOR signaling(GO:0032006) |
| 0.0 | 0.4 | GO:0000002 | mitochondrial genome maintenance(GO:0000002) |
| 0.0 | 1.1 | GO:0007601 | visual perception(GO:0007601) |
| 0.0 | 0.1 | GO:0006654 | phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473) |
| 0.0 | 0.1 | GO:0048733 | sebaceous gland development(GO:0048733) |
| 0.0 | 0.7 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
| 0.0 | 0.6 | GO:0000462 | maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462) |
| 0.0 | 0.1 | GO:0044314 | protein K27-linked ubiquitination(GO:0044314) |
| 0.0 | 0.5 | GO:0006284 | base-excision repair(GO:0006284) |
| 0.0 | 0.3 | GO:0007608 | sensory perception of smell(GO:0007608) |
| 0.0 | 1.1 | GO:0043484 | regulation of RNA splicing(GO:0043484) |
| 0.0 | 0.2 | GO:0006693 | prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693) |
| 0.0 | 0.2 | GO:0000038 | very long-chain fatty acid metabolic process(GO:0000038) |
| 0.0 | 0.3 | GO:0030968 | endoplasmic reticulum unfolded protein response(GO:0030968) |
| 0.0 | 0.4 | GO:0000387 | spliceosomal snRNP assembly(GO:0000387) |
| 0.0 | 0.5 | GO:0003341 | cilium movement(GO:0003341) |
| 0.0 | 0.2 | GO:0006783 | heme biosynthetic process(GO:0006783) |
| 0.0 | 0.6 | GO:0046488 | phosphatidylinositol metabolic process(GO:0046488) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 6.5 | 19.4 | GO:0071953 | elastic fiber(GO:0071953) |
| 4.8 | 19.3 | GO:0045251 | mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251) |
| 4.3 | 21.3 | GO:0097149 | centralspindlin complex(GO:0097149) |
| 3.1 | 9.3 | GO:0071149 | TEAD-2-YAP complex(GO:0071149) |
| 2.3 | 7.0 | GO:0097059 | CNTFR-CLCF1 complex(GO:0097059) |
| 2.3 | 11.4 | GO:0002193 | MAML1-RBP-Jkappa- ICN1 complex(GO:0002193) |
| 1.9 | 5.7 | GO:0045009 | melanosome membrane(GO:0033162) chitosome(GO:0045009) |
| 1.8 | 23.7 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) |
| 1.7 | 8.7 | GO:0008622 | epsilon DNA polymerase complex(GO:0008622) |
| 1.6 | 3.2 | GO:0005833 | hemoglobin complex(GO:0005833) |
| 1.6 | 4.7 | GO:0005967 | mitochondrial pyruvate dehydrogenase complex(GO:0005967) |
| 1.3 | 5.4 | GO:0032021 | NELF complex(GO:0032021) |
| 1.3 | 11.5 | GO:0030478 | actin cap(GO:0030478) |
| 0.9 | 6.3 | GO:0001740 | Barr body(GO:0001740) |
| 0.9 | 2.6 | GO:0031251 | PAN complex(GO:0031251) |
| 0.9 | 5.1 | GO:0043256 | laminin complex(GO:0043256) |
| 0.8 | 3.4 | GO:0034991 | nuclear meiotic cohesin complex(GO:0034991) |
| 0.8 | 3.0 | GO:0014802 | terminal cisterna(GO:0014802) |
| 0.7 | 5.7 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
| 0.7 | 14.1 | GO:0000145 | exocyst(GO:0000145) |
| 0.7 | 2.1 | GO:1990851 | Wnt-Frizzled-LRP5/6 complex(GO:1990851) |
| 0.7 | 2.7 | GO:0043564 | Ku70:Ku80 complex(GO:0043564) |
| 0.7 | 2.7 | GO:0097487 | multivesicular body, internal vesicle(GO:0097487) |
| 0.7 | 7.2 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
| 0.6 | 1.3 | GO:0051286 | cell tip(GO:0051286) |
| 0.6 | 3.6 | GO:0016035 | zeta DNA polymerase complex(GO:0016035) |
| 0.6 | 3.0 | GO:1990130 | Iml1 complex(GO:1990130) |
| 0.6 | 6.5 | GO:0042571 | immunoglobulin complex, circulating(GO:0042571) |
| 0.6 | 2.9 | GO:0097226 | sperm mitochondrial sheath(GO:0097226) |
| 0.6 | 2.8 | GO:1990037 | Lewy body core(GO:1990037) |
| 0.5 | 4.7 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
| 0.5 | 6.0 | GO:0043205 | microfibril(GO:0001527) fibril(GO:0043205) |
| 0.5 | 8.0 | GO:0051233 | spindle midzone(GO:0051233) |
| 0.5 | 2.9 | GO:0070531 | BRCA1-A complex(GO:0070531) |
| 0.5 | 4.7 | GO:0001739 | sex chromatin(GO:0001739) |
| 0.4 | 1.7 | GO:1990452 | Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452) |
| 0.4 | 4.1 | GO:0032982 | myosin filament(GO:0032982) |
| 0.4 | 6.0 | GO:0042788 | polysomal ribosome(GO:0042788) |
| 0.4 | 65.6 | GO:0090575 | RNA polymerase II transcription factor complex(GO:0090575) |
| 0.4 | 16.0 | GO:0034707 | chloride channel complex(GO:0034707) |
| 0.4 | 5.7 | GO:0042101 | T cell receptor complex(GO:0042101) |
| 0.3 | 2.3 | GO:0042825 | TAP complex(GO:0042825) |
| 0.3 | 66.0 | GO:0005777 | peroxisome(GO:0005777) microbody(GO:0042579) |
| 0.3 | 3.6 | GO:0043240 | Fanconi anaemia nuclear complex(GO:0043240) |
| 0.3 | 8.8 | GO:0045334 | clathrin-coated endocytic vesicle(GO:0045334) |
| 0.3 | 4.2 | GO:0044322 | endoplasmic reticulum quality control compartment(GO:0044322) |
| 0.3 | 5.6 | GO:0097431 | mitotic spindle pole(GO:0097431) |
| 0.3 | 2.2 | GO:0001520 | outer dense fiber(GO:0001520) |
| 0.3 | 2.7 | GO:0000347 | THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445) |
| 0.3 | 1.1 | GO:0000931 | gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274) |
| 0.3 | 1.9 | GO:0097165 | nuclear stress granule(GO:0097165) |
| 0.3 | 0.5 | GO:0042585 | germinal vesicle(GO:0042585) |
| 0.3 | 2.8 | GO:0061700 | Seh1-associated complex(GO:0035859) GATOR2 complex(GO:0061700) |
| 0.2 | 3.9 | GO:0031082 | BLOC complex(GO:0031082) |
| 0.2 | 26.7 | GO:0005814 | centriole(GO:0005814) |
| 0.2 | 1.7 | GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex(GO:0031465) |
| 0.2 | 0.7 | GO:0030934 | collagen type XII trimer(GO:0005595) anchoring collagen complex(GO:0030934) |
| 0.2 | 11.3 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
| 0.2 | 20.7 | GO:0000922 | spindle pole(GO:0000922) |
| 0.2 | 0.9 | GO:0097454 | Schwann cell microvillus(GO:0097454) |
| 0.2 | 7.6 | GO:0001772 | immunological synapse(GO:0001772) |
| 0.2 | 0.9 | GO:0097450 | astrocyte end-foot(GO:0097450) |
| 0.2 | 0.9 | GO:0030906 | retromer, cargo-selective complex(GO:0030906) |
| 0.2 | 4.3 | GO:0010369 | chromocenter(GO:0010369) |
| 0.2 | 3.1 | GO:0031528 | microvillus membrane(GO:0031528) |
| 0.2 | 2.4 | GO:0044666 | MLL3/4 complex(GO:0044666) |
| 0.2 | 1.2 | GO:0030056 | hemidesmosome(GO:0030056) |
| 0.2 | 1.9 | GO:0016460 | myosin II complex(GO:0016460) |
| 0.2 | 1.5 | GO:0031931 | TORC1 complex(GO:0031931) |
| 0.2 | 2.4 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.2 | 1.3 | GO:0071012 | catalytic step 1 spliceosome(GO:0071012) |
| 0.2 | 2.3 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
| 0.2 | 3.5 | GO:0005942 | phosphatidylinositol 3-kinase complex(GO:0005942) |
| 0.2 | 2.5 | GO:0017119 | Golgi transport complex(GO:0017119) |
| 0.2 | 4.6 | GO:0097038 | perinuclear endoplasmic reticulum(GO:0097038) |
| 0.2 | 1.3 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
| 0.2 | 2.9 | GO:0071564 | npBAF complex(GO:0071564) |
| 0.2 | 4.8 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
| 0.2 | 7.0 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
| 0.2 | 2.6 | GO:0005682 | U5 snRNP(GO:0005682) |
| 0.1 | 2.8 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
| 0.1 | 2.0 | GO:0000506 | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506) |
| 0.1 | 0.7 | GO:0034715 | U7 snRNP(GO:0005683) pICln-Sm protein complex(GO:0034715) |
| 0.1 | 0.4 | GO:0030690 | Noc1p-Noc2p complex(GO:0030690) |
| 0.1 | 4.5 | GO:0030673 | axolemma(GO:0030673) |
| 0.1 | 4.1 | GO:0044798 | nuclear transcription factor complex(GO:0044798) |
| 0.1 | 2.3 | GO:0005721 | pericentric heterochromatin(GO:0005721) |
| 0.1 | 1.4 | GO:0035631 | CD40 receptor complex(GO:0035631) |
| 0.1 | 7.2 | GO:0005811 | lipid particle(GO:0005811) |
| 0.1 | 3.9 | GO:0030496 | midbody(GO:0030496) |
| 0.1 | 7.1 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
| 0.1 | 3.7 | GO:1990391 | DNA repair complex(GO:1990391) |
| 0.1 | 1.3 | GO:0035253 | ciliary rootlet(GO:0035253) |
| 0.1 | 0.9 | GO:0030991 | intraciliary transport particle A(GO:0030991) |
| 0.1 | 4.8 | GO:0005844 | polysome(GO:0005844) |
| 0.1 | 13.7 | GO:0001650 | fibrillar center(GO:0001650) |
| 0.1 | 11.5 | GO:0032993 | protein-DNA complex(GO:0032993) |
| 0.1 | 2.9 | GO:0016592 | mediator complex(GO:0016592) |
| 0.1 | 1.1 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
| 0.1 | 7.9 | GO:0005903 | brush border(GO:0005903) |
| 0.1 | 0.7 | GO:0070765 | gamma-secretase complex(GO:0070765) |
| 0.1 | 5.3 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
| 0.1 | 1.4 | GO:0065010 | extracellular membrane-bounded organelle(GO:0065010) |
| 0.1 | 5.7 | GO:0030136 | clathrin-coated vesicle(GO:0030136) |
| 0.1 | 3.0 | GO:0005720 | nuclear heterochromatin(GO:0005720) |
| 0.1 | 21.4 | GO:0016607 | nuclear speck(GO:0016607) |
| 0.1 | 0.7 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
| 0.1 | 0.9 | GO:0042612 | MHC class I protein complex(GO:0042612) |
| 0.1 | 1.4 | GO:0016581 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
| 0.1 | 8.8 | GO:0005741 | mitochondrial outer membrane(GO:0005741) |
| 0.1 | 0.8 | GO:1904115 | axon cytoplasm(GO:1904115) |
| 0.1 | 5.8 | GO:0071013 | catalytic step 2 spliceosome(GO:0071013) |
| 0.1 | 2.7 | GO:0001669 | acrosomal vesicle(GO:0001669) |
| 0.1 | 3.9 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
| 0.1 | 43.5 | GO:0005694 | chromosome(GO:0005694) |
| 0.1 | 0.2 | GO:0005745 | m-AAA complex(GO:0005745) |
| 0.1 | 3.1 | GO:0016529 | sarcoplasmic reticulum(GO:0016529) |
| 0.1 | 0.7 | GO:0008541 | proteasome regulatory particle, lid subcomplex(GO:0008541) |
| 0.1 | 2.9 | GO:0042645 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
| 0.1 | 3.4 | GO:0005793 | endoplasmic reticulum-Golgi intermediate compartment(GO:0005793) |
| 0.1 | 0.9 | GO:0030992 | intraciliary transport particle B(GO:0030992) |
| 0.1 | 5.2 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.1 | 2.2 | GO:0016459 | myosin complex(GO:0016459) |
| 0.1 | 1.2 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
| 0.1 | 4.9 | GO:0005681 | spliceosomal complex(GO:0005681) |
| 0.1 | 0.8 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.1 | 0.7 | GO:0032045 | guanyl-nucleotide exchange factor complex(GO:0032045) |
| 0.1 | 1.4 | GO:0005865 | striated muscle thin filament(GO:0005865) myofilament(GO:0036379) |
| 0.1 | 1.1 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 0.1 | 1.9 | GO:0005901 | caveola(GO:0005901) |
| 0.0 | 1.4 | GO:0016591 | DNA-directed RNA polymerase II, holoenzyme(GO:0016591) |
| 0.0 | 5.1 | GO:0030176 | integral component of endoplasmic reticulum membrane(GO:0030176) |
| 0.0 | 0.2 | GO:0098574 | cytoplasmic side of lysosomal membrane(GO:0098574) |
| 0.0 | 1.1 | GO:0035097 | histone methyltransferase complex(GO:0035097) |
| 0.0 | 3.1 | GO:0045121 | membrane raft(GO:0045121) membrane microdomain(GO:0098857) |
| 0.0 | 0.9 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.0 | 0.8 | GO:0032040 | small-subunit processome(GO:0032040) |
| 0.0 | 0.3 | GO:0005795 | Golgi stack(GO:0005795) |
| 0.0 | 1.0 | GO:0097014 | axoneme(GO:0005930) ciliary plasm(GO:0097014) |
| 0.0 | 12.3 | GO:0005730 | nucleolus(GO:0005730) |
| 0.0 | 0.8 | GO:0031201 | SNARE complex(GO:0031201) |
| 0.0 | 4.3 | GO:0016604 | nuclear body(GO:0016604) |
| 0.0 | 0.1 | GO:0031227 | intrinsic component of endoplasmic reticulum membrane(GO:0031227) |
| 0.0 | 78.6 | GO:0005634 | nucleus(GO:0005634) |
| 0.0 | 1.0 | GO:0000315 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
| 0.0 | 0.0 | GO:0042588 | zymogen granule(GO:0042588) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 9.8 | 39.4 | GO:0016647 | oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647) |
| 5.9 | 35.6 | GO:0010997 | anaphase-promoting complex binding(GO:0010997) |
| 5.5 | 11.0 | GO:0070991 | medium-chain-acyl-CoA dehydrogenase activity(GO:0070991) |
| 3.9 | 11.8 | GO:0017099 | very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099) |
| 3.2 | 9.7 | GO:0008310 | single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310) |
| 3.1 | 9.4 | GO:1990050 | phosphatidic acid transporter activity(GO:1990050) |
| 2.9 | 14.4 | GO:0043515 | kinetochore binding(GO:0043515) |
| 2.8 | 19.6 | GO:0016918 | retinal binding(GO:0016918) |
| 2.6 | 10.5 | GO:0004174 | electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649) |
| 2.5 | 7.6 | GO:0030171 | voltage-gated proton channel activity(GO:0030171) |
| 2.5 | 12.6 | GO:0072542 | protein phosphatase activator activity(GO:0072542) |
| 2.5 | 7.4 | GO:0005332 | gamma-aminobutyric acid:sodium symporter activity(GO:0005332) |
| 2.5 | 7.4 | GO:0098770 | FBXO family protein binding(GO:0098770) |
| 2.4 | 9.8 | GO:0008422 | beta-glucosidase activity(GO:0008422) |
| 2.4 | 21.4 | GO:0031730 | CCR5 chemokine receptor binding(GO:0031730) |
| 2.3 | 29.5 | GO:0003995 | acyl-CoA dehydrogenase activity(GO:0003995) |
| 2.1 | 8.5 | GO:0043546 | molybdenum ion binding(GO:0030151) molybdopterin cofactor binding(GO:0043546) |
| 2.1 | 6.3 | GO:0004145 | diamine N-acetyltransferase activity(GO:0004145) |
| 1.8 | 7.2 | GO:0004032 | alditol:NADP+ 1-oxidoreductase activity(GO:0004032) |
| 1.8 | 9.0 | GO:0004095 | carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416) |
| 1.8 | 5.3 | GO:1990450 | linear polyubiquitin binding(GO:1990450) |
| 1.7 | 6.9 | GO:0004515 | nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515) |
| 1.5 | 4.6 | GO:0030156 | benzodiazepine receptor binding(GO:0030156) |
| 1.5 | 12.3 | GO:0005095 | GTPase inhibitor activity(GO:0005095) |
| 1.5 | 8.9 | GO:0009374 | biotin binding(GO:0009374) |
| 1.4 | 11.6 | GO:0046790 | virion binding(GO:0046790) |
| 1.4 | 5.4 | GO:0016842 | amidine-lyase activity(GO:0016842) |
| 1.3 | 5.3 | GO:0003941 | L-serine ammonia-lyase activity(GO:0003941) |
| 1.3 | 3.9 | GO:0005118 | sevenless binding(GO:0005118) |
| 1.3 | 14.2 | GO:0008430 | selenium binding(GO:0008430) |
| 1.3 | 3.8 | GO:0016494 | C-X-C chemokine receptor activity(GO:0016494) |
| 1.2 | 5.0 | GO:0047844 | deoxycytidine deaminase activity(GO:0047844) |
| 1.2 | 3.6 | GO:0050501 | hyaluronan synthase activity(GO:0050501) |
| 1.2 | 12.9 | GO:0031957 | very long-chain fatty acid-CoA ligase activity(GO:0031957) |
| 1.2 | 4.7 | GO:0004740 | pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740) |
| 1.1 | 5.7 | GO:0035240 | dopamine binding(GO:0035240) |
| 1.1 | 8.9 | GO:0048403 | brain-derived neurotrophic factor binding(GO:0048403) |
| 1.1 | 5.6 | GO:0070051 | fibrinogen binding(GO:0070051) |
| 1.1 | 18.4 | GO:0009982 | pseudouridine synthase activity(GO:0009982) |
| 1.0 | 17.4 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
| 1.0 | 19.2 | GO:0035497 | cAMP response element binding(GO:0035497) |
| 1.0 | 4.0 | GO:0004064 | arylesterase activity(GO:0004064) |
| 0.9 | 5.4 | GO:0004897 | ciliary neurotrophic factor receptor activity(GO:0004897) |
| 0.9 | 3.6 | GO:0034647 | histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647) |
| 0.9 | 7.1 | GO:0086008 | voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008) |
| 0.9 | 2.6 | GO:0005219 | ryanodine-sensitive calcium-release channel activity(GO:0005219) |
| 0.9 | 9.4 | GO:0019992 | diacylglycerol binding(GO:0019992) |
| 0.8 | 2.5 | GO:0008823 | cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851) |
| 0.8 | 3.2 | GO:0031721 | hemoglobin alpha binding(GO:0031721) |
| 0.7 | 4.4 | GO:0042731 | PH domain binding(GO:0042731) |
| 0.7 | 8.0 | GO:0009922 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
| 0.7 | 7.2 | GO:0022848 | acetylcholine-gated cation channel activity(GO:0022848) |
| 0.7 | 2.8 | GO:0048408 | epidermal growth factor binding(GO:0048408) |
| 0.7 | 2.1 | GO:0071936 | coreceptor activity involved in Wnt signaling pathway(GO:0071936) |
| 0.7 | 8.2 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
| 0.7 | 12.2 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
| 0.7 | 4.0 | GO:0003910 | DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910) |
| 0.6 | 8.3 | GO:0005522 | profilin binding(GO:0005522) |
| 0.6 | 8.9 | GO:1990825 | sequence-specific mRNA binding(GO:1990825) |
| 0.6 | 5.7 | GO:0030274 | LIM domain binding(GO:0030274) |
| 0.6 | 3.8 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
| 0.6 | 1.2 | GO:0004075 | biotin carboxylase activity(GO:0004075) |
| 0.6 | 10.9 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
| 0.6 | 14.5 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
| 0.5 | 4.7 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
| 0.5 | 2.1 | GO:0016971 | flavin-linked sulfhydryl oxidase activity(GO:0016971) |
| 0.5 | 3.5 | GO:0046935 | 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935) |
| 0.5 | 3.0 | GO:0004332 | fructose-bisphosphate aldolase activity(GO:0004332) |
| 0.5 | 1.5 | GO:0070892 | lipoteichoic acid receptor activity(GO:0070892) |
| 0.5 | 4.4 | GO:0097200 | cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200) |
| 0.5 | 9.3 | GO:0001134 | transcription factor activity, transcription factor recruiting(GO:0001134) |
| 0.5 | 3.3 | GO:0004303 | estradiol 17-beta-dehydrogenase activity(GO:0004303) |
| 0.5 | 3.3 | GO:0031432 | titin binding(GO:0031432) |
| 0.5 | 6.5 | GO:0070742 | C2H2 zinc finger domain binding(GO:0070742) |
| 0.5 | 2.8 | GO:0046912 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912) |
| 0.5 | 3.2 | GO:0071558 | histone demethylase activity (H3-K27 specific)(GO:0071558) |
| 0.5 | 1.4 | GO:0008384 | IkappaB kinase activity(GO:0008384) |
| 0.5 | 4.6 | GO:0001727 | lipid kinase activity(GO:0001727) |
| 0.4 | 6.7 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.4 | 15.2 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.4 | 3.0 | GO:0031995 | insulin-like growth factor II binding(GO:0031995) |
| 0.4 | 22.1 | GO:0001102 | RNA polymerase II activating transcription factor binding(GO:0001102) |
| 0.4 | 8.0 | GO:0005044 | scavenger receptor activity(GO:0005044) |
| 0.4 | 33.9 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.4 | 1.7 | GO:0015410 | manganese-transporting ATPase activity(GO:0015410) |
| 0.4 | 1.6 | GO:0035473 | lipase binding(GO:0035473) |
| 0.4 | 6.5 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
| 0.4 | 2.4 | GO:0070728 | leucine binding(GO:0070728) |
| 0.4 | 7.6 | GO:0005035 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
| 0.4 | 18.2 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.4 | 1.6 | GO:0015254 | glycerol channel activity(GO:0015254) |
| 0.4 | 2.3 | GO:0046978 | TAP1 binding(GO:0046978) TAP2 binding(GO:0046979) |
| 0.4 | 1.1 | GO:0005105 | type 1 fibroblast growth factor receptor binding(GO:0005105) |
| 0.3 | 16.8 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
| 0.3 | 20.2 | GO:0005548 | phospholipid transporter activity(GO:0005548) |
| 0.3 | 3.8 | GO:0016861 | intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861) |
| 0.3 | 5.4 | GO:0008253 | 5'-nucleotidase activity(GO:0008253) |
| 0.3 | 1.3 | GO:0016774 | phosphotransferase activity, carboxyl group as acceptor(GO:0016774) |
| 0.3 | 3.6 | GO:0048531 | beta-1,3-galactosyltransferase activity(GO:0048531) |
| 0.3 | 1.3 | GO:0032896 | palmitoyl-CoA 9-desaturase activity(GO:0032896) |
| 0.3 | 1.6 | GO:0016941 | natriuretic peptide receptor activity(GO:0016941) |
| 0.3 | 1.3 | GO:0036435 | K48-linked polyubiquitin binding(GO:0036435) |
| 0.3 | 1.0 | GO:0031686 | A1 adenosine receptor binding(GO:0031686) |
| 0.3 | 1.3 | GO:0004096 | aminoacylase activity(GO:0004046) catalase activity(GO:0004096) |
| 0.3 | 1.6 | GO:0016803 | ether hydrolase activity(GO:0016803) |
| 0.3 | 4.0 | GO:0004300 | enoyl-CoA hydratase activity(GO:0004300) |
| 0.3 | 6.4 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
| 0.3 | 2.7 | GO:0030550 | acetylcholine receptor inhibitor activity(GO:0030550) |
| 0.3 | 12.1 | GO:0033613 | activating transcription factor binding(GO:0033613) |
| 0.3 | 18.5 | GO:0070491 | repressing transcription factor binding(GO:0070491) |
| 0.3 | 4.1 | GO:0022889 | L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889) |
| 0.3 | 0.6 | GO:0019211 | phosphatase activator activity(GO:0019211) |
| 0.3 | 4.8 | GO:0042800 | histone methyltransferase activity (H3-K4 specific)(GO:0042800) |
| 0.3 | 7.0 | GO:0097602 | cullin family protein binding(GO:0097602) |
| 0.3 | 2.7 | GO:0051575 | 5'-deoxyribose-5-phosphate lyase activity(GO:0051575) |
| 0.3 | 0.8 | GO:0000402 | open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402) |
| 0.3 | 10.7 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.3 | 0.8 | GO:0033592 | RNA strand annealing activity(GO:0033592) |
| 0.2 | 0.7 | GO:0008527 | taste receptor activity(GO:0008527) |
| 0.2 | 2.5 | GO:0008474 | palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599) |
| 0.2 | 3.7 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
| 0.2 | 8.3 | GO:0005112 | Notch binding(GO:0005112) |
| 0.2 | 5.1 | GO:0008143 | poly(A) binding(GO:0008143) |
| 0.2 | 1.9 | GO:0070739 | protein-glutamic acid ligase activity(GO:0070739) |
| 0.2 | 7.4 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
| 0.2 | 13.8 | GO:0005254 | chloride channel activity(GO:0005254) |
| 0.2 | 1.4 | GO:0002054 | nucleobase binding(GO:0002054) |
| 0.2 | 0.9 | GO:0043208 | glycosphingolipid binding(GO:0043208) |
| 0.2 | 1.4 | GO:0008239 | dipeptidyl-peptidase activity(GO:0008239) |
| 0.2 | 26.5 | GO:0004725 | protein tyrosine phosphatase activity(GO:0004725) |
| 0.2 | 7.2 | GO:0008307 | structural constituent of muscle(GO:0008307) |
| 0.2 | 2.4 | GO:0003689 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
| 0.2 | 1.7 | GO:0070324 | thyroid hormone binding(GO:0070324) |
| 0.2 | 6.5 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
| 0.2 | 7.5 | GO:0000975 | regulatory region DNA binding(GO:0000975) transcription regulatory region DNA binding(GO:0044212) |
| 0.2 | 2.3 | GO:0004017 | adenylate kinase activity(GO:0004017) |
| 0.2 | 1.0 | GO:0004839 | ubiquitin activating enzyme activity(GO:0004839) |
| 0.2 | 0.6 | GO:0004028 | 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028) |
| 0.2 | 0.6 | GO:0004616 | phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616) |
| 0.2 | 1.0 | GO:0004499 | N,N-dimethylaniline monooxygenase activity(GO:0004499) |
| 0.2 | 2.8 | GO:0001848 | complement binding(GO:0001848) |
| 0.2 | 0.6 | GO:0071633 | dihydroceramidase activity(GO:0071633) |
| 0.2 | 1.5 | GO:1990380 | Lys48-specific deubiquitinase activity(GO:1990380) |
| 0.2 | 2.0 | GO:0017176 | phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176) |
| 0.2 | 0.6 | GO:0031752 | D5 dopamine receptor binding(GO:0031752) |
| 0.2 | 0.9 | GO:0086080 | protein binding involved in heterotypic cell-cell adhesion(GO:0086080) |
| 0.2 | 1.6 | GO:1990247 | N6-methyladenosine-containing RNA binding(GO:1990247) |
| 0.2 | 6.3 | GO:0017091 | AU-rich element binding(GO:0017091) |
| 0.2 | 1.6 | GO:0004128 | cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128) |
| 0.2 | 19.8 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 0.2 | 0.7 | GO:0015226 | amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226) |
| 0.2 | 5.4 | GO:0031435 | mitogen-activated protein kinase kinase kinase binding(GO:0031435) |
| 0.2 | 0.6 | GO:0004694 | eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694) |
| 0.2 | 2.2 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
| 0.2 | 1.1 | GO:0061665 | SUMO ligase activity(GO:0061665) |
| 0.2 | 7.8 | GO:0050660 | flavin adenine dinucleotide binding(GO:0050660) |
| 0.2 | 0.8 | GO:0004382 | guanosine-diphosphatase activity(GO:0004382) |
| 0.2 | 1.7 | GO:0008227 | G-protein coupled amine receptor activity(GO:0008227) |
| 0.2 | 0.5 | GO:0008311 | double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311) |
| 0.2 | 7.8 | GO:0008528 | G-protein coupled peptide receptor activity(GO:0008528) |
| 0.1 | 2.7 | GO:0047555 | 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555) |
| 0.1 | 0.3 | GO:0008131 | primary amine oxidase activity(GO:0008131) |
| 0.1 | 13.1 | GO:0005178 | integrin binding(GO:0005178) |
| 0.1 | 0.6 | GO:0019003 | GDP binding(GO:0019003) |
| 0.1 | 3.7 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 0.1 | 2.6 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
| 0.1 | 1.8 | GO:0043495 | protein anchor(GO:0043495) |
| 0.1 | 0.8 | GO:0033192 | calmodulin-dependent protein phosphatase activity(GO:0033192) |
| 0.1 | 0.6 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) |
| 0.1 | 3.7 | GO:0019707 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
| 0.1 | 1.6 | GO:0005149 | interleukin-1 receptor binding(GO:0005149) |
| 0.1 | 21.9 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
| 0.1 | 0.7 | GO:0008479 | queuine tRNA-ribosyltransferase activity(GO:0008479) |
| 0.1 | 0.4 | GO:0004830 | tryptophan-tRNA ligase activity(GO:0004830) |
| 0.1 | 1.1 | GO:0051011 | microtubule minus-end binding(GO:0051011) |
| 0.1 | 5.9 | GO:0005249 | voltage-gated potassium channel activity(GO:0005249) |
| 0.1 | 1.1 | GO:0045125 | bioactive lipid receptor activity(GO:0045125) |
| 0.1 | 0.4 | GO:0004035 | alkaline phosphatase activity(GO:0004035) |
| 0.1 | 1.0 | GO:0004745 | retinol dehydrogenase activity(GO:0004745) |
| 0.1 | 3.7 | GO:0016504 | peptidase activator activity(GO:0016504) |
| 0.1 | 1.6 | GO:0046527 | glucosyltransferase activity(GO:0046527) |
| 0.1 | 0.5 | GO:0004849 | uridine kinase activity(GO:0004849) |
| 0.1 | 4.5 | GO:0030170 | pyridoxal phosphate binding(GO:0030170) |
| 0.1 | 0.8 | GO:0003993 | acid phosphatase activity(GO:0003993) |
| 0.1 | 7.4 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.1 | 1.8 | GO:0050431 | transforming growth factor beta binding(GO:0050431) |
| 0.1 | 3.1 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
| 0.1 | 0.5 | GO:0033142 | progesterone receptor binding(GO:0033142) |
| 0.1 | 2.8 | GO:0000993 | RNA polymerase II core binding(GO:0000993) |
| 0.1 | 0.4 | GO:0004565 | beta-galactosidase activity(GO:0004565) |
| 0.1 | 3.8 | GO:0031593 | polyubiquitin binding(GO:0031593) |
| 0.1 | 5.4 | GO:0004540 | ribonuclease activity(GO:0004540) |
| 0.1 | 20.5 | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) |
| 0.1 | 0.5 | GO:0035368 | selenocysteine insertion sequence binding(GO:0035368) |
| 0.1 | 0.5 | GO:0042609 | CD4 receptor binding(GO:0042609) |
| 0.1 | 0.6 | GO:0001055 | RNA polymerase II activity(GO:0001055) |
| 0.1 | 0.2 | GO:0036132 | 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522) |
| 0.1 | 1.8 | GO:0031491 | nucleosome binding(GO:0031491) |
| 0.1 | 7.3 | GO:0003774 | motor activity(GO:0003774) |
| 0.1 | 0.8 | GO:0048038 | quinone binding(GO:0048038) |
| 0.1 | 2.4 | GO:0043028 | cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028) |
| 0.1 | 0.3 | GO:0031735 | CCR10 chemokine receptor binding(GO:0031735) |
| 0.1 | 1.6 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
| 0.1 | 1.5 | GO:0004129 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
| 0.1 | 0.7 | GO:0030296 | protein tyrosine kinase activator activity(GO:0030296) |
| 0.1 | 0.7 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
| 0.1 | 1.7 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
| 0.1 | 9.4 | GO:0042393 | histone binding(GO:0042393) |
| 0.1 | 2.3 | GO:0030332 | cyclin binding(GO:0030332) |
| 0.1 | 5.3 | GO:0001047 | core promoter binding(GO:0001047) |
| 0.1 | 9.1 | GO:0004386 | helicase activity(GO:0004386) |
| 0.1 | 1.8 | GO:0004177 | aminopeptidase activity(GO:0004177) |
| 0.1 | 4.4 | GO:0003714 | transcription corepressor activity(GO:0003714) |
| 0.1 | 0.5 | GO:0046977 | TAP binding(GO:0046977) |
| 0.1 | 0.7 | GO:0002161 | aminoacyl-tRNA editing activity(GO:0002161) |
| 0.1 | 1.3 | GO:0048487 | beta-tubulin binding(GO:0048487) |
| 0.1 | 3.7 | GO:0008081 | phosphoric diester hydrolase activity(GO:0008081) |
| 0.1 | 0.3 | GO:0004984 | olfactory receptor activity(GO:0004984) |
| 0.1 | 0.3 | GO:0042975 | peroxisome proliferator activated receptor binding(GO:0042975) |
| 0.0 | 1.0 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
| 0.0 | 0.5 | GO:0070181 | small ribosomal subunit rRNA binding(GO:0070181) |
| 0.0 | 0.2 | GO:0015143 | urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702) |
| 0.0 | 0.1 | GO:0019966 | interleukin-1 binding(GO:0019966) |
| 0.0 | 8.9 | GO:0008017 | microtubule binding(GO:0008017) |
| 0.0 | 12.8 | GO:0003682 | chromatin binding(GO:0003682) |
| 0.0 | 0.2 | GO:0004103 | choline kinase activity(GO:0004103) |
| 0.0 | 1.5 | GO:0003823 | antigen binding(GO:0003823) |
| 0.0 | 8.2 | GO:0061659 | ubiquitin-like protein ligase activity(GO:0061659) |
| 0.0 | 1.1 | GO:0051087 | chaperone binding(GO:0051087) |
| 0.0 | 0.9 | GO:0008200 | ion channel inhibitor activity(GO:0008200) |
| 0.0 | 0.2 | GO:0051959 | dynein light intermediate chain binding(GO:0051959) |
| 0.0 | 0.1 | GO:0008392 | arachidonic acid epoxygenase activity(GO:0008392) |
| 0.0 | 1.6 | GO:0017022 | myosin binding(GO:0017022) |
| 0.0 | 1.1 | GO:0001104 | RNA polymerase II transcription cofactor activity(GO:0001104) |
| 0.0 | 1.4 | GO:0003705 | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705) |
| 0.0 | 0.2 | GO:0003906 | DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906) |
| 0.0 | 0.6 | GO:0017025 | TBP-class protein binding(GO:0017025) |
| 0.0 | 0.7 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
| 0.0 | 0.6 | GO:0005310 | dicarboxylic acid transmembrane transporter activity(GO:0005310) |
| 0.0 | 0.8 | GO:0030544 | Hsp70 protein binding(GO:0030544) |
| 0.0 | 1.3 | GO:0000981 | RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981) |
| 0.0 | 8.7 | GO:0005525 | GTP binding(GO:0005525) |
| 0.0 | 0.5 | GO:0009055 | electron carrier activity(GO:0009055) |
| 0.0 | 0.7 | GO:0004527 | exonuclease activity(GO:0004527) |
| 0.0 | 0.5 | GO:0035326 | enhancer binding(GO:0035326) |
| 0.0 | 0.4 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
| 0.0 | 3.2 | GO:0044822 | mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822) |
| 0.0 | 0.8 | GO:0005484 | SNAP receptor activity(GO:0005484) |
| 0.0 | 5.5 | GO:0043565 | sequence-specific DNA binding(GO:0043565) |
| 0.0 | 0.8 | GO:0048306 | calcium-dependent protein binding(GO:0048306) |
| 0.0 | 0.3 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
| 0.0 | 0.3 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.0 | 0.1 | GO:0005078 | MAP-kinase scaffold activity(GO:0005078) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.3 | 79.3 | PID_PLK1_PATHWAY | PLK1 signaling events |
| 1.2 | 21.4 | ST_STAT3_PATHWAY | STAT3 Pathway |
| 0.9 | 1.7 | PID_BETA_CATENIN_DEG_PATHWAY | Degradation of beta catenin |
| 0.9 | 40.3 | PID_HNF3B_PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.6 | 5.1 | PID_INTEGRIN4_PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.6 | 1.1 | ST_JAK_STAT_PATHWAY | Jak-STAT Pathway |
| 0.4 | 8.5 | PID_ERBB1_RECEPTOR_PROXIMAL_PATHWAY | EGF receptor (ErbB1) signaling pathway |
| 0.3 | 10.4 | PID_WNT_SIGNALING_PATHWAY | Wnt signaling network |
| 0.3 | 10.0 | PID_NEPHRIN_NEPH1_PATHWAY | Nephrin/Neph1 signaling in the kidney podocyte |
| 0.3 | 9.8 | PID_NETRIN_PATHWAY | Netrin-mediated signaling events |
| 0.3 | 43.9 | NABA_ECM_GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.3 | 9.3 | PID_INSULIN_GLUCOSE_PATHWAY | Insulin-mediated glucose transport |
| 0.3 | 16.7 | PID_PS1_PATHWAY | Presenilin action in Notch and Wnt signaling |
| 0.3 | 12.0 | PID_TRAIL_PATHWAY | TRAIL signaling pathway |
| 0.3 | 8.6 | PID_FOXM1_PATHWAY | FOXM1 transcription factor network |
| 0.3 | 7.4 | PID_IL2_STAT5_PATHWAY | IL2 signaling events mediated by STAT5 |
| 0.2 | 9.2 | PID_BARD1_PATHWAY | BARD1 signaling events |
| 0.2 | 5.7 | PID_P38_MK2_PATHWAY | p38 signaling mediated by MAPKAP kinases |
| 0.2 | 5.7 | PID_HDAC_CLASSIII_PATHWAY | Signaling events mediated by HDAC Class III |
| 0.2 | 4.7 | PID_INTEGRIN_A9B1_PATHWAY | Alpha9 beta1 integrin signaling events |
| 0.2 | 3.0 | ST_WNT_CA2_CYCLIC_GMP_PATHWAY | Wnt/Ca2+/cyclic GMP signaling. |
| 0.2 | 3.3 | PID_WNT_NONCANONICAL_PATHWAY | Noncanonical Wnt signaling pathway |
| 0.2 | 9.9 | PID_ECADHERIN_STABILIZATION_PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
| 0.2 | 1.9 | PID_INTEGRIN2_PATHWAY | Beta2 integrin cell surface interactions |
| 0.2 | 7.8 | ST_T_CELL_SIGNAL_TRANSDUCTION | T Cell Signal Transduction |
| 0.2 | 3.3 | PID_EPHRINB_REV_PATHWAY | Ephrin B reverse signaling |
| 0.1 | 3.0 | PID_HIF1_TFPATHWAY | HIF-1-alpha transcription factor network |
| 0.1 | 4.1 | ST_ERK1_ERK2_MAPK_PATHWAY | ERK1/ERK2 MAPK Pathway |
| 0.1 | 0.8 | PID_SYNDECAN_3_PATHWAY | Syndecan-3-mediated signaling events |
| 0.1 | 5.3 | PID_P75_NTR_PATHWAY | p75(NTR)-mediated signaling |
| 0.1 | 1.5 | PID_FOXO_PATHWAY | FoxO family signaling |
| 0.1 | 11.7 | NABA_ECM_REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.1 | 2.1 | PID_ATM_PATHWAY | ATM pathway |
| 0.1 | 1.9 | PID_ECADHERIN_NASCENT_AJ_PATHWAY | E-cadherin signaling in the nascent adherens junction |
| 0.1 | 0.1 | PID_TCR_RAS_PATHWAY | Ras signaling in the CD4+ TCR pathway |
| 0.1 | 0.8 | PID_AMB2_NEUTROPHILS_PATHWAY | amb2 Integrin signaling |
| 0.1 | 2.7 | PID_MET_PATHWAY | Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) |
| 0.1 | 1.1 | PID_HEDGEHOG_GLI_PATHWAY | Hedgehog signaling events mediated by Gli proteins |
| 0.1 | 0.6 | PID_THROMBIN_PAR4_PATHWAY | PAR4-mediated thrombin signaling events |
| 0.1 | 2.8 | NABA_COLLAGENS | Genes encoding collagen proteins |
| 0.1 | 3.3 | WNT_SIGNALING | Genes related to Wnt-mediated signal transduction |
| 0.1 | 1.5 | PID_FGF_PATHWAY | FGF signaling pathway |
| 0.1 | 2.0 | PID_AP1_PATHWAY | AP-1 transcription factor network |
| 0.1 | 1.0 | PID_FRA_PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
| 0.1 | 5.3 | PID_P53_DOWNSTREAM_PATHWAY | Direct p53 effectors |
| 0.1 | 0.7 | ST_WNT_BETA_CATENIN_PATHWAY | Wnt/beta-catenin Pathway |
| 0.1 | 0.8 | PID_DELTA_NP63_PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.1 | 0.7 | PID_P38_GAMMA_DELTA_PATHWAY | Signaling mediated by p38-gamma and p38-delta |
| 0.1 | 3.1 | PID_ERA_GENOMIC_PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.0 | 0.4 | PID_ANTHRAX_PATHWAY | Cellular roles of Anthrax toxin |
| 0.0 | 0.7 | PID_IL6_7_PATHWAY | IL6-mediated signaling events |
| 0.0 | 1.1 | PID_IL12_2PATHWAY | IL12-mediated signaling events |
| 0.0 | 2.1 | PID_P53_REGULATION_PATHWAY | p53 pathway |
| 0.0 | 2.0 | PID_AR_TF_PATHWAY | Regulation of Androgen receptor activity |
| 0.0 | 0.7 | PID_ARF6_PATHWAY | Arf6 signaling events |
| 0.0 | 0.2 | PID_TOLL_ENDOGENOUS_PATHWAY | Endogenous TLR signaling |
| 0.0 | 0.5 | PID_RB_1PATHWAY | Regulation of retinoblastoma protein |
| 0.0 | 0.3 | PID_GLYPICAN_1PATHWAY | Glypican 1 network |
| 0.0 | 0.2 | PID_ARF6_DOWNSTREAM_PATHWAY | Arf6 downstream pathway |
| 0.0 | 0.6 | PID_BMP_PATHWAY | BMP receptor signaling |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.3 | 56.8 | REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION | Genes involved in Mitochondrial Fatty Acid Beta-Oxidation |
| 1.8 | 21.4 | REACTOME_IL_6_SIGNALING | Genes involved in Interleukin-6 signaling |
| 1.5 | 11.7 | REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol |
| 1.2 | 19.5 | REACTOME_ASSOCIATION_OF_LICENSING_FACTORS_WITH_THE_PRE_REPLICATIVE_COMPLEX | Genes involved in Association of licensing factors with the pre-replicative complex |
| 1.1 | 6.5 | REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
| 0.9 | 7.2 | REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS | Genes involved in Presynaptic nicotinic acetylcholine receptors |
| 0.8 | 18.0 | REACTOME_APC_CDC20_MEDIATED_DEGRADATION_OF_NEK2A | Genes involved in APC-Cdc20 mediated degradation of Nek2A |
| 0.6 | 8.3 | REACTOME_IRAK1_RECRUITS_IKK_COMPLEX | Genes involved in IRAK1 recruits IKK complex |
| 0.6 | 16.4 | REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS | Genes involved in Regulation of gene expression in beta cells |
| 0.6 | 6.8 | REACTOME_AMINE_DERIVED_HORMONES | Genes involved in Amine-derived hormones |
| 0.6 | 11.3 | REACTOME_GAP_JUNCTION_DEGRADATION | Genes involved in Gap junction degradation |
| 0.6 | 1.7 | REACTOME_DOWNSTREAM_SIGNALING_EVENTS_OF_B_CELL_RECEPTOR_BCR | Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR) |
| 0.5 | 5.9 | REACTOME_PURINE_CATABOLISM | Genes involved in Purine catabolism |
| 0.5 | 10.5 | REACTOME_EARLY_PHASE_OF_HIV_LIFE_CYCLE | Genes involved in Early Phase of HIV Life Cycle |
| 0.5 | 7.5 | REACTOME_REPAIR_SYNTHESIS_FOR_GAP_FILLING_BY_DNA_POL_IN_TC_NER | Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER |
| 0.5 | 4.8 | REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS | Genes involved in Na+/Cl- dependent neurotransmitter transporters |
| 0.5 | 17.2 | REACTOME_SMOOTH_MUSCLE_CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.4 | 16.4 | REACTOME_MYOGENESIS | Genes involved in Myogenesis |
| 0.4 | 3.6 | REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
| 0.3 | 9.4 | REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
| 0.3 | 4.4 | REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX | Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex |
| 0.3 | 3.5 | REACTOME_IL_7_SIGNALING | Genes involved in Interleukin-7 signaling |
| 0.3 | 4.9 | REACTOME_METABOLISM_OF_POLYAMINES | Genes involved in Metabolism of polyamines |
| 0.3 | 12.2 | REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS | Genes involved in Voltage gated Potassium channels |
| 0.3 | 5.8 | REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE | Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle |
| 0.3 | 8.9 | REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
| 0.3 | 10.6 | REACTOME_INTEGRIN_ALPHAIIB_BETA3_SIGNALING | Genes involved in Integrin alphaIIb beta3 signaling |
| 0.2 | 3.2 | REACTOME_STRIATED_MUSCLE_CONTRACTION | Genes involved in Striated Muscle Contraction |
| 0.2 | 13.8 | REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
| 0.2 | 10.4 | REACTOME_MRNA_3_END_PROCESSING | Genes involved in mRNA 3'-end processing |
| 0.2 | 6.6 | REACTOME_DEADENYLATION_OF_MRNA | Genes involved in Deadenylation of mRNA |
| 0.2 | 16.3 | REACTOME_RESPIRATORY_ELECTRON_TRANSPORT | Genes involved in Respiratory electron transport |
| 0.2 | 4.8 | REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
| 0.2 | 1.7 | REACTOME_PROLACTIN_RECEPTOR_SIGNALING | Genes involved in Prolactin receptor signaling |
| 0.2 | 1.2 | REACTOME_COMMON_PATHWAY | Genes involved in Common Pathway |
| 0.2 | 1.4 | REACTOME_PYRIMIDINE_CATABOLISM | Genes involved in Pyrimidine catabolism |
| 0.2 | 1.6 | REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS | Genes involved in Passive Transport by Aquaporins |
| 0.2 | 3.0 | REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| 0.2 | 7.7 | REACTOME_GLYCOLYSIS | Genes involved in Glycolysis |
| 0.2 | 1.5 | REACTOME_FGFR4_LIGAND_BINDING_AND_ACTIVATION | Genes involved in FGFR4 ligand binding and activation |
| 0.2 | 1.6 | REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA | Genes involved in Activation of Chaperone Genes by ATF6-alpha |
| 0.2 | 3.6 | REACTOME_FANCONI_ANEMIA_PATHWAY | Genes involved in Fanconi Anemia pathway |
| 0.2 | 7.0 | REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS | Genes involved in O-linked glycosylation of mucins |
| 0.2 | 3.3 | REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII | Genes involved in CREB phosphorylation through the activation of CaMKII |
| 0.2 | 1.1 | REACTOME_REGULATION_OF_IFNG_SIGNALING | Genes involved in Regulation of IFNG signaling |
| 0.2 | 27.3 | REACTOME_SIGNALING_BY_RHO_GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.2 | 5.4 | REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS | Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus |
| 0.2 | 2.0 | REACTOME_ACTIVATION_OF_RAC | Genes involved in Activation of Rac |
| 0.1 | 3.9 | REACTOME_PEROXISOMAL_LIPID_METABOLISM | Genes involved in Peroxisomal lipid metabolism |
| 0.1 | 1.0 | REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT | Genes involved in Regulation of beta-cell development |
| 0.1 | 4.3 | REACTOME_G1_PHASE | Genes involved in G1 Phase |
| 0.1 | 4.2 | REACTOME_INTERFERON_ALPHA_BETA_SIGNALING | Genes involved in Interferon alpha/beta signaling |
| 0.1 | 2.3 | REACTOME_ACTIVATION_OF_GENES_BY_ATF4 | Genes involved in Activation of Genes by ATF4 |
| 0.1 | 1.4 | REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS | Genes involved in Extrinsic Pathway for Apoptosis |
| 0.1 | 3.1 | REACTOME_PIP3_ACTIVATES_AKT_SIGNALING | Genes involved in PIP3 activates AKT signaling |
| 0.1 | 1.3 | REACTOME_P38MAPK_EVENTS | Genes involved in p38MAPK events |
| 0.1 | 1.4 | REACTOME_AMINE_LIGAND_BINDING_RECEPTORS | Genes involved in Amine ligand-binding receptors |
| 0.1 | 2.9 | REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
| 0.1 | 6.7 | REACTOME_COLLAGEN_FORMATION | Genes involved in Collagen formation |
| 0.1 | 0.3 | REACTOME_ACTIVATION_OF_CHAPERONES_BY_ATF6_ALPHA | Genes involved in Activation of Chaperones by ATF6-alpha |
| 0.1 | 1.1 | REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES | Genes involved in Recruitment of NuMA to mitotic centrosomes |
| 0.1 | 7.8 | REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS | Genes involved in Peptide ligand-binding receptors |
| 0.1 | 0.5 | REACTOME_PECAM1_INTERACTIONS | Genes involved in PECAM1 interactions |
| 0.1 | 3.1 | REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS | Genes involved in Integrin cell surface interactions |
| 0.1 | 3.4 | REACTOME_MEIOSIS | Genes involved in Meiosis |
| 0.1 | 2.7 | REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING | Genes involved in Negative regulators of RIG-I/MDA5 signaling |
| 0.1 | 1.4 | REACTOME_REGULATION_OF_KIT_SIGNALING | Genes involved in Regulation of KIT signaling |
| 0.1 | 1.2 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE | Genes involved in Synthesis of PIPs at the early endosome membrane |
| 0.1 | 2.1 | REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS | Genes involved in Activation of ATR in response to replication stress |
| 0.1 | 6.4 | REACTOME_CELL_JUNCTION_ORGANIZATION | Genes involved in Cell junction organization |
| 0.1 | 1.0 | REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
| 0.1 | 0.8 | REACTOME_RAF_MAP_KINASE_CASCADE | Genes involved in RAF/MAP kinase cascade |
| 0.1 | 0.9 | REACTOME_INTERFERON_GAMMA_SIGNALING | Genes involved in Interferon gamma signaling |
| 0.1 | 0.7 | REACTOME_PROCESSING_OF_CAPPED_INTRONLESS_PRE_MRNA | Genes involved in Processing of Capped Intronless Pre-mRNA |
| 0.1 | 0.7 | REACTOME_ELONGATION_ARREST_AND_RECOVERY | Genes involved in Elongation arrest and recovery |
| 0.1 | 1.6 | REACTOME_MEIOTIC_RECOMBINATION | Genes involved in Meiotic Recombination |
| 0.1 | 4.3 | REACTOME_DNA_REPAIR | Genes involved in DNA Repair |
| 0.1 | 1.6 | REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI | Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) |
| 0.1 | 1.1 | REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS | Genes involved in Phase 1 - Functionalization of compounds |
| 0.1 | 0.8 | REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
| 0.1 | 2.6 | REACTOME_INTERFERON_SIGNALING | Genes involved in Interferon Signaling |
| 0.1 | 1.3 | REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER | Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter |
| 0.0 | 3.3 | REACTOME_ANTIGEN_PROCESSING_CROSS_PRESENTATION | Genes involved in Antigen processing-Cross presentation |
| 0.0 | 1.7 | REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES | Genes involved in Ion transport by P-type ATPases |
| 0.0 | 1.1 | REACTOME_SIGNALING_BY_HIPPO | Genes involved in Signaling by Hippo |
| 0.0 | 1.1 | REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
| 0.0 | 0.2 | REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR | Genes involved in Trafficking and processing of endosomal TLR |
| 0.0 | 1.5 | REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.0 | 0.4 | REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.0 | 0.4 | REACTOME_JNK_C_JUN_KINASES_PHOSPHORYLATION_AND_ACTIVATION_MEDIATED_BY_ACTIVATED_HUMAN_TAK1 | Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 |
| 0.0 | 0.3 | REACTOME_SIGNALING_BY_CONSTITUTIVELY_ACTIVE_EGFR | Genes involved in Signaling by constitutively active EGFR |
| 0.0 | 0.1 | REACTOME_RIG_I_MDA5_MEDIATED_INDUCTION_OF_IFN_ALPHA_BETA_PATHWAYS | Genes involved in RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways |
| 0.0 | 0.6 | REACTOME_SIGNALING_BY_BMP | Genes involved in Signaling by BMP |
| 0.0 | 0.7 | REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS | Genes involved in Class A/1 (Rhodopsin-like receptors) |
| 0.0 | 0.4 | REACTOME_CHOLESTEROL_BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
| 0.0 | 0.2 | REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
| 0.0 | 0.4 | REACTOME_CGMP_EFFECTS | Genes involved in cGMP effects |
| 0.0 | 0.8 | REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS | Genes involved in Amino acid and oligopeptide SLC transporters |
| 0.0 | 0.7 | REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
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