Motif ID: Prdm14

Z-value: 0.360


Transcription factors associated with Prdm14:

Gene SymbolEntrez IDGene Name
Prdm14 ENSMUSG00000042414.7 Prdm14



Activity profile for motif Prdm14.

activity profile for motif Prdm14


Sorted Z-values histogram for motif Prdm14

Sorted Z-values for motif Prdm14



Network of associatons between targets according to the STRING database.



First level regulatory network of Prdm14

PNG image of the network

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Top targets:


Showing 1 to 20 of 38 entries
PromoterScoreRefseqGene SymbolGene Name
chr16_+_43235856 3.220 ENSMUST00000146708.1
Zbtb20
zinc finger and BTB domain containing 20
chr12_+_74297474 2.897 ENSMUST00000072100.3
Dbpht2
DNA binding protein with his-thr domain
chr6_+_72355425 2.591 ENSMUST00000069695.2
ENSMUST00000132243.1
Tmem150a

transmembrane protein 150A

chr10_-_128744014 2.075 ENSMUST00000026414.7
Dgka
diacylglycerol kinase, alpha
chr15_+_18818895 1.767 ENSMUST00000166873.2
Cdh10
cadherin 10
chr9_+_94669876 1.588 ENSMUST00000033463.9
Slc9a9
solute carrier family 9 (sodium/hydrogen exchanger), member 9
chr4_-_88438900 1.440 ENSMUST00000132493.1
ENSMUST00000030221.2
ENSMUST00000151280.1
Ptplad2


protein tyrosine phosphatase-like A domain containing 2


chr4_+_119814495 1.402 ENSMUST00000106307.2
Hivep3
human immunodeficiency virus type I enhancer binding protein 3
chrX_+_99042581 1.308 ENSMUST00000036606.7
Stard8
START domain containing 8
chr7_+_18987518 1.118 ENSMUST00000063563.7
Nanos2
nanos homolog 2 (Drosophila)
chr7_+_114745685 1.079 ENSMUST00000136645.1
ENSMUST00000169913.1
Insc

inscuteable homolog (Drosophila)

chr8_+_46492789 1.028 ENSMUST00000110371.1
Acsl1
acyl-CoA synthetase long-chain family member 1
chr15_+_99601372 1.024 ENSMUST00000023754.5
Aqp6
aquaporin 6
chr11_-_89302545 0.999 ENSMUST00000061728.3
Nog
noggin
chr17_+_33555719 0.892 ENSMUST00000087605.5
ENSMUST00000174695.1
Myo1f

myosin IF

chr18_+_37307445 0.792 ENSMUST00000056712.2
Pcdhb4
protocadherin beta 4
chr15_-_76307231 0.790 ENSMUST00000023222.6
ENSMUST00000164189.1
Oplah

5-oxoprolinase (ATP-hydrolysing)

chr15_-_76307101 0.709 ENSMUST00000171340.1
Oplah
5-oxoprolinase (ATP-hydrolysing)
chr7_+_27810813 0.574 ENSMUST00000080175.6
Zfp626
zinc finger protein 626
chr18_-_15063560 0.560 ENSMUST00000168989.1
Kctd1
potassium channel tetramerisation domain containing 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 20 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.2 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 2.6 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.2 2.1 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 1.8 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.2 1.6 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 1.5 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 1.4 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.2 1.1 GO:0044838 germ-line stem cell population maintenance(GO:0030718) cell quiescence(GO:0044838)
0.0 1.1 GO:0000132 establishment of mitotic spindle orientation(GO:0000132)
0.2 1.0 GO:2000313 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.1 1.0 GO:0044539 long-chain fatty acid import(GO:0044539)
0.1 1.0 GO:0006833 water transport(GO:0006833)
0.1 0.9 GO:0043312 neutrophil degranulation(GO:0043312)
0.1 0.7 GO:0071494 cellular response to UV-C(GO:0071494)
0.1 0.6 GO:0052695 cellular glucuronidation(GO:0052695)
0.1 0.6 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.4 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.4 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 0.2 GO:0042256 mature ribosome assembly(GO:0042256)
0.0 0.1 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)

Gene overrepresentation in cellular_component category:

Showing 1 to 4 of 4 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.8 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 1.6 GO:0055037 recycling endosome(GO:0055037)
0.0 1.0 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.9 GO:0031941 filamentous actin(GO:0031941)

Gene overrepresentation in molecular_function category:

Showing 1 to 15 of 15 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.2 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.2 2.1 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.2 1.6 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.4 1.5 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.3 1.0 GO:0043758 acetate-CoA ligase (ADP-forming) activity(GO:0043758)
0.1 1.0 GO:0015250 water channel activity(GO:0015250)
0.0 1.0 GO:0019955 cytokine binding(GO:0019955)
0.0 0.7 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 0.6 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.6 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.5 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.1 0.4 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.2 GO:0033592 RNA strand annealing activity(GO:0033592)
0.0 0.2 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.2 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)

Gene overrepresentation in C2:CP category:

Showing 1 to 2 of 2 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.1 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.0 PID_BMP_PATHWAY BMP receptor signaling

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 10 of 10 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.1 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 1.8 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.6 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 1.5 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.1 1.0 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 1.0 REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 1.0 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.0 0.6 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.5 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.4 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC