Motif ID: Prdm4

Z-value: 0.473


Transcription factors associated with Prdm4:

Gene SymbolEntrez IDGene Name
Prdm4 ENSMUSG00000035529.9 Prdm4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Prdm4mm10_v2_chr10_-_85916902_859170060.009.7e-01Click!


Activity profile for motif Prdm4.

activity profile for motif Prdm4


Sorted Z-values histogram for motif Prdm4

Sorted Z-values for motif Prdm4



Network of associatons between targets according to the STRING database.



First level regulatory network of Prdm4

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_+_102604370 10.615 ENSMUST00000057893.5
 Fzd2
frizzled homolog 2 (Drosophila)
chr1_+_74391479 6.939 ENSMUST00000027367.7
 Ctdsp1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr10_+_126978690 5.558 ENSMUST00000105256.2
 Ctdsp2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr5_-_4758216 4.534 ENSMUST00000054294.4
 Fzd1
frizzled homolog 1 (Drosophila)
chr10_+_26822560 3.063 ENSMUST00000135866.1
 Arhgap18
Rho GTPase activating protein 18
chr19_-_4163285 1.364 ENSMUST00000118483.1
ENSMUST00000025749.7
 Rps6kb2

ribosomal protein S6 kinase, polypeptide 2

chr17_+_24473884 1.324 ENSMUST00000054946.3
ENSMUST00000164508.1
 Bricd5

BRICHOS domain containing 5

chr5_-_142817654 1.014 ENSMUST00000151477.1
 Tnrc18
trinucleotide repeat containing 18
chr11_-_69369377 0.636 ENSMUST00000092971.6
ENSMUST00000108661.1
 Chd3

chromodomain helicase DNA binding protein 3

chr5_-_142817387 0.545 ENSMUST00000036253.6
 Tnrc18
trinucleotide repeat containing 18
chr9_+_17030045 0.417 ENSMUST00000164523.2
 Gm5611
predicted gene 5611
chr5_-_144965793 0.384 ENSMUST00000110677.1
ENSMUST00000085684.4
ENSMUST00000100461.2
 Smurf1


SMAD specific E3 ubiquitin protein ligase 1


chr7_-_30743681 0.104 ENSMUST00000182634.1
 Gapdhs
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr8_+_27042555 0.083 ENSMUST00000033875.8
ENSMUST00000098851.4
 Prosc

proline synthetase co-transcribed


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 15.1 GO:0060022 hard palate development(GO:0060022)
0.2 12.5 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.1 0.4 GO:0071211 protein targeting to vacuole involved in autophagy(GO:0071211)
0.1 1.6 GO:0031507 heterochromatin assembly(GO:0031507)
0.1 1.4 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 3.1 GO:0030833 regulation of actin filament polymerization(GO:0030833)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 15.1 GO:0005925 focal adhesion(GO:0005925)
0.0 0.6 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 12.5 GO:0008420 CTD phosphatase activity(GO:0008420)
0.7 15.1 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.5 1.4 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.1 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.4 GO:0070411 I-SMAD binding(GO:0070411)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 15.1 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.4 12.5 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.0 PID_HDAC_CLASSI_PATHWAY Signaling events mediated by HDAC Class I

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 15.1 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 5.6 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 1.4 REACTOME_PIP3_ACTIVATES_AKT_SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.4 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 3.1 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases