Motif ID: Rad21_Smc3

Z-value: 0.788

Transcription factors associated with Rad21_Smc3:

Gene SymbolEntrez IDGene Name
Rad21 ENSMUSG00000022314.9 Rad21
Smc3 ENSMUSG00000024974.10 Smc3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Smc3mm10_v2_chr19_+_53600377_53600435-0.342.9e-03Click!
Rad21mm10_v2_chr15_-_51991679_51991760-0.075.6e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Rad21_Smc3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_-_110168204 8.589 ENSMUST00000003754.6
Calb2
calbindin 2
chr11_-_114795888 7.292 ENSMUST00000000206.3
Btbd17
BTB (POZ) domain containing 17
chr2_-_117342709 6.070 ENSMUST00000173541.1
ENSMUST00000172901.1
ENSMUST00000173252.1
Rasgrp1


RAS guanyl releasing protein 1


chr7_+_35119285 5.803 ENSMUST00000042985.9
Cebpa
CCAAT/enhancer binding protein (C/EBP), alpha
chr8_+_119446719 5.145 ENSMUST00000098363.3
Necab2
N-terminal EF-hand calcium binding protein 2
chr18_-_34007206 5.114 ENSMUST00000025234.5
Epb4.1l4a
erythrocyte protein band 4.1-like 4a
chr2_+_157914618 4.787 ENSMUST00000109523.1
Vstm2l
V-set and transmembrane domain containing 2-like
chr9_-_42944479 4.704 ENSMUST00000114865.1
Grik4
glutamate receptor, ionotropic, kainate 4
chr7_+_16891755 4.498 ENSMUST00000078182.4
Gng8
guanine nucleotide binding protein (G protein), gamma 8
chr7_+_25686994 4.313 ENSMUST00000002678.9
Tgfb1
transforming growth factor, beta 1
chr7_-_19698206 4.113 ENSMUST00000172808.1
ENSMUST00000174191.1
Apoe

apolipoprotein E

chr2_+_172550991 4.026 ENSMUST00000170744.1
Tfap2c
transcription factor AP-2, gamma
chr11_-_59964936 4.012 ENSMUST00000062405.7
Rasd1
RAS, dexamethasone-induced 1
chr7_-_19698383 3.862 ENSMUST00000173739.1
Apoe
apolipoprotein E
chr3_+_90612869 3.841 ENSMUST00000001051.4
S100a6
S100 calcium binding protein A6 (calcyclin)
chr8_+_87473116 3.702 ENSMUST00000182650.1
ENSMUST00000182758.1
ENSMUST00000181898.1
Gm2694


predicted gene 2694


chr7_-_15967470 3.599 ENSMUST00000144956.1
ENSMUST00000098799.3
Ehd2

EH-domain containing 2

chr3_+_104789011 3.537 ENSMUST00000002303.5
ENSMUST00000106787.1
ENSMUST00000176347.1
Rhoc


ras homolog gene family, member C


chr5_+_91517615 3.403 ENSMUST00000040576.9
Parm1
prostate androgen-regulated mucin-like protein 1
chr8_+_87472805 3.396 ENSMUST00000180700.2
ENSMUST00000182174.1
ENSMUST00000181159.1
Gm2694


predicted gene 2694


chr7_-_79594924 3.356 ENSMUST00000172788.1
Rhcg
Rhesus blood group-associated C glycoprotein
chr4_-_45530330 3.316 ENSMUST00000061986.5
Shb
src homology 2 domain-containing transforming protein B
chr17_-_33890584 3.297 ENSMUST00000114361.2
ENSMUST00000173492.1
Kifc1

kinesin family member C1

chr9_-_96889381 3.289 ENSMUST00000112951.2
ENSMUST00000126411.1
ENSMUST00000078478.1
ENSMUST00000119141.1
ENSMUST00000120101.1
Acpl2




acid phosphatase-like 2




chr17_+_47737030 3.271 ENSMUST00000086932.3
Tfeb
transcription factor EB
chr5_+_17574268 3.232 ENSMUST00000030568.7
Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr2_-_158146385 3.227 ENSMUST00000103122.3
Tgm2
transglutaminase 2, C polypeptide
chr17_+_26917091 3.219 ENSMUST00000078961.4
Kifc5b
kinesin family member C5B
chr2_+_167538192 3.180 ENSMUST00000052631.7
Snai1
snail homolog 1 (Drosophila)
chr13_-_113046357 3.156 ENSMUST00000022282.3
Gpx8
glutathione peroxidase 8 (putative)
chr1_+_192190771 3.007 ENSMUST00000078470.5
ENSMUST00000110844.1
Kcnh1

potassium voltage-gated channel, subfamily H (eag-related), member 1

chr17_-_33890539 2.964 ENSMUST00000173386.1
Kifc1
kinesin family member C1
chr4_+_41762309 2.935 ENSMUST00000108042.2
Il11ra1
interleukin 11 receptor, alpha chain 1
chr14_+_47472547 2.922 ENSMUST00000168833.1
ENSMUST00000163324.1
ENSMUST00000043112.7
Fbxo34


F-box protein 34


chr4_+_41755210 2.853 ENSMUST00000108038.1
ENSMUST00000084695.4
Galt

galactose-1-phosphate uridyl transferase

chr9_+_123478693 2.830 ENSMUST00000026269.2
Limd1
LIM domains containing 1
chr11_+_78826575 2.818 ENSMUST00000147875.2
ENSMUST00000141321.1
Lyrm9

LYR motif containing 9

chr3_+_90220783 2.790 ENSMUST00000065418.6
Rab13
RAB13, member RAS oncogene family
chr17_-_56036546 2.717 ENSMUST00000003268.9
Sh3gl1
SH3-domain GRB2-like 1
chr9_-_86464900 2.715 ENSMUST00000121189.1
Ube2cbp
ubiquitin-conjugating enzyme E2C binding protein
chr3_-_84155762 2.674 ENSMUST00000047368.6
Mnd1
meiotic nuclear divisions 1 homolog (S. cerevisiae)
chr14_+_47472628 2.603 ENSMUST00000095941.2
Fbxo34
F-box protein 34
chr9_-_86464944 2.566 ENSMUST00000034986.7
Ube2cbp
ubiquitin-conjugating enzyme E2C binding protein
chr10_-_31445921 2.559 ENSMUST00000000305.5
Tpd52l1
tumor protein D52-like 1
chr8_+_87472838 2.548 ENSMUST00000180806.2
Gm2694
predicted gene 2694
chr7_-_127026479 2.522 ENSMUST00000032916.4
Maz
MYC-associated zinc finger protein (purine-binding transcription factor)
chr13_-_35027077 2.502 ENSMUST00000170538.1
ENSMUST00000163280.1
Eci2

enoyl-Coenzyme A delta isomerase 2

chr7_+_31059342 2.499 ENSMUST00000039775.7
Lgi4
leucine-rich repeat LGI family, member 4
chr8_-_122432924 2.455 ENSMUST00000017604.8
Cyba
cytochrome b-245, alpha polypeptide
chr19_+_43752996 2.432 ENSMUST00000026199.7
ENSMUST00000112047.3
ENSMUST00000153295.1
Cutc


cutC copper transporter homolog (E.coli)


chr8_-_122678653 2.428 ENSMUST00000134045.1
Cbfa2t3
core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)
chrX_-_140600497 2.392 ENSMUST00000112996.2
Tsc22d3
TSC22 domain family, member 3
chr5_+_30921556 2.392 ENSMUST00000031053.8
Khk
ketohexokinase
chr9_+_66158206 2.377 ENSMUST00000034944.2
Dapk2
death-associated protein kinase 2
chr5_+_147957310 2.370 ENSMUST00000085558.4
ENSMUST00000129092.1
Mtus2

microtubule associated tumor suppressor candidate 2

chr11_+_69632927 2.367 ENSMUST00000018909.3
Fxr2
fragile X mental retardation, autosomal homolog 2
chr5_-_36398090 2.332 ENSMUST00000037370.7
ENSMUST00000070720.6
Sorcs2

sortilin-related VPS10 domain containing receptor 2

chr2_-_91963507 2.308 ENSMUST00000028667.3
Dgkz
diacylglycerol kinase zeta
chr11_-_69880971 2.275 ENSMUST00000050555.3
Kctd11
potassium channel tetramerisation domain containing 11
chr11_-_115813621 2.265 ENSMUST00000041684.4
ENSMUST00000156812.1
Caskin2

CASK-interacting protein 2

chr2_+_26586607 2.238 ENSMUST00000174211.1
ENSMUST00000145575.2
ENSMUST00000173920.1
Egfl7


EGF-like domain 7


chr5_+_30921825 2.235 ENSMUST00000117435.1
Khk
ketohexokinase
chr5_+_30921867 2.227 ENSMUST00000123885.1
Khk
ketohexokinase
chr8_+_70282978 2.081 ENSMUST00000110124.2
Homer3
homer homolog 3 (Drosophila)
chr1_-_193273099 2.035 ENSMUST00000009777.2
G0s2
G0/G1 switch gene 2
chr12_-_84876479 2.020 ENSMUST00000163189.1
ENSMUST00000110254.2
ENSMUST00000002073.6
Ltbp2


latent transforming growth factor beta binding protein 2


chr10_-_10558199 2.003 ENSMUST00000019974.3
Rab32
RAB32, member RAS oncogene family
chr16_-_84735742 2.001 ENSMUST00000116584.1
Mrpl39
mitochondrial ribosomal protein L39
chr14_-_46788267 1.974 ENSMUST00000015903.4
Cnih1
cornichon homolog 1 (Drosophila)
chr15_-_99705490 1.961 ENSMUST00000163472.2
Gm17349
predicted gene, 17349
chr13_+_98354234 1.960 ENSMUST00000105098.3
Foxd1
forkhead box D1
chr4_-_132345686 1.928 ENSMUST00000030726.6
Rcc1
regulator of chromosome condensation 1
chr2_+_172550761 1.922 ENSMUST00000099058.3
Tfap2c
transcription factor AP-2, gamma
chr4_+_140701466 1.914 ENSMUST00000038893.5
ENSMUST00000138808.1
Rcc2

regulator of chromosome condensation 2

chr5_-_130024280 1.897 ENSMUST00000161640.1
ENSMUST00000161884.1
ENSMUST00000161094.1
Asl


argininosuccinate lyase


chr4_-_126468580 1.884 ENSMUST00000097888.3
Ago1
argonaute RISC catalytic subunit 1
chr17_+_56613392 1.870 ENSMUST00000080492.5
Rpl36
ribosomal protein L36
chr9_-_108452377 1.854 ENSMUST00000035232.7
Klhdc8b
kelch domain containing 8B
chr3_-_5576233 1.825 ENSMUST00000059021.4
Pex2
peroxisomal biogenesis factor 2
chr17_+_45563928 1.809 ENSMUST00000041353.6
Slc35b2
solute carrier family 35, member B2
chr4_-_132345715 1.806 ENSMUST00000084250.4
Rcc1
regulator of chromosome condensation 1
chr7_-_109170308 1.788 ENSMUST00000036992.7
Lmo1
LIM domain only 1
chr19_-_6969746 1.785 ENSMUST00000025912.8
Plcb3
phospholipase C, beta 3
chr5_+_140331860 1.779 ENSMUST00000071881.3
ENSMUST00000050205.5
ENSMUST00000110827.1
Nudt1


nudix (nucleoside diphosphate linked moiety X)-type motif 1


chr3_-_5576111 1.779 ENSMUST00000165309.1
ENSMUST00000164828.1
ENSMUST00000071280.5
Pex2


peroxisomal biogenesis factor 2


chr7_+_108934405 1.763 ENSMUST00000033342.6
Eif3f
eukaryotic translation initiation factor 3, subunit F
chr4_+_122995944 1.734 ENSMUST00000106252.2
Mycl
v-myc myelocytomatosis viral oncogene homolog, lung carcinoma derived (avian)
chr3_-_121171678 1.727 ENSMUST00000170781.1
ENSMUST00000039761.5
ENSMUST00000106467.1
ENSMUST00000106466.3
ENSMUST00000164925.2
Rwdd3




RWD domain containing 3




chrX_-_102189371 1.727 ENSMUST00000033683.7
Rps4x
ribosomal protein S4, X-linked
chr19_+_46304709 1.653 ENSMUST00000073116.5
Nfkb2
nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100
chr2_+_91096744 1.640 ENSMUST00000132741.2
Spi1
spleen focus forming virus (SFFV) proviral integration oncogene
chr3_-_87768932 1.626 ENSMUST00000173184.1
ENSMUST00000172621.1
ENSMUST00000174759.1
ENSMUST00000172590.1
ENSMUST00000079083.5
Pear1




platelet endothelial aggregation receptor 1




chr3_-_96708524 1.625 ENSMUST00000029742.5
ENSMUST00000171249.1
Nudt17

nudix (nucleoside diphosphate linked moiety X)-type motif 17

chr5_+_114707760 1.615 ENSMUST00000094441.4
Tchp
trichoplein, keratin filament binding
chr17_+_65783355 1.605 ENSMUST00000073104.4
ENSMUST00000160664.1
ENSMUST00000162272.1
Ppp4r1


protein phosphatase 4, regulatory subunit 1


chr16_-_10785525 1.595 ENSMUST00000038099.4
Socs1
suppressor of cytokine signaling 1
chr4_-_45108038 1.594 ENSMUST00000107809.2
ENSMUST00000107808.2
ENSMUST00000107807.1
ENSMUST00000107810.2
Tomm5



translocase of outer mitochondrial membrane 5 homolog (yeast)



chr11_+_114668524 1.584 ENSMUST00000106602.3
ENSMUST00000077915.3
ENSMUST00000106599.1
ENSMUST00000082092.4
Rpl38



ribosomal protein L38



chr2_+_29619692 1.571 ENSMUST00000095087.4
ENSMUST00000091146.5
ENSMUST00000102872.4
Rapgef1


Rap guanine nucleotide exchange factor (GEF) 1


chr9_-_50528641 1.563 ENSMUST00000034570.5
Pts
6-pyruvoyl-tetrahydropterin synthase
chr5_-_117115972 1.529 ENSMUST00000086471.5
ENSMUST00000166397.1
Suds3

suppressor of defective silencing 3 homolog (S. cerevisiae)

chr14_+_122181694 1.528 ENSMUST00000026625.5
Clybl
citrate lyase beta like
chr12_-_101028983 1.526 ENSMUST00000068411.3
ENSMUST00000085096.3
Ccdc88c

coiled-coil domain containing 88C

chr11_-_102579071 1.524 ENSMUST00000107080.1
Gm11627
predicted gene 11627
chr9_+_120110349 1.498 ENSMUST00000035106.5
Slc25a38
solute carrier family 25, member 38
chr11_+_63133068 1.497 ENSMUST00000108700.1
Pmp22
peripheral myelin protein 22
chr10_-_127030813 1.491 ENSMUST00000040560.4
Tsfm
Ts translation elongation factor, mitochondrial
chr8_-_84937347 1.488 ENSMUST00000109741.2
ENSMUST00000119820.1
Mast1

microtubule associated serine/threonine kinase 1

chr8_+_85171322 1.481 ENSMUST00000076896.5
Gm6531
predicted gene 6531
chr5_-_143315360 1.445 ENSMUST00000046418.2
E130309D02Rik
RIKEN cDNA E130309D02 gene
chr14_-_77036641 1.431 ENSMUST00000062789.8
Lacc1
laccase (multicopper oxidoreductase) domain containing 1
chr8_+_71464910 1.426 ENSMUST00000048914.6
Mrpl34
mitochondrial ribosomal protein L34
chr1_+_91366412 1.411 ENSMUST00000086861.5
Fam132b
family with sequence similarity 132, member B
chr13_+_35741313 1.408 ENSMUST00000163595.2
Cdyl
chromodomain protein, Y chromosome-like
chr7_-_45136231 1.399 ENSMUST00000124300.1
ENSMUST00000085377.5
Rpl13a
Flt3l
ribosomal protein L13A
FMS-like tyrosine kinase 3 ligand
chr4_+_86575668 1.394 ENSMUST00000091064.6
Rraga
Ras-related GTP binding A
chr7_+_141455198 1.386 ENSMUST00000164016.1
ENSMUST00000064151.6
ENSMUST00000169665.1
Pnpla2


patatin-like phospholipase domain containing 2


chr11_-_69579320 1.385 ENSMUST00000048139.5
Wrap53
WD repeat containing, antisense to Trp53
chr6_-_137169678 1.366 ENSMUST00000119610.1
Rerg
RAS-like, estrogen-regulated, growth-inhibitor
chr14_-_69707493 1.366 ENSMUST00000121142.1
R3hcc1
R3H domain and coiled-coil containing 1
chr16_+_18052860 1.366 ENSMUST00000143343.1
Dgcr6
DiGeorge syndrome critical region gene 6
chr7_-_34655500 1.360 ENSMUST00000032709.1
Kctd15
potassium channel tetramerisation domain containing 15
chr5_-_5749317 1.336 ENSMUST00000015796.2
Steap1
six transmembrane epithelial antigen of the prostate 1
chr3_+_142560351 1.330 ENSMUST00000106221.1
Gbp3
guanylate binding protein 3
chr4_-_89311021 1.324 ENSMUST00000097981.4
Cdkn2b
cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
chr11_+_68901538 1.315 ENSMUST00000073471.6
ENSMUST00000101014.2
ENSMUST00000128952.1
ENSMUST00000167436.1
Rpl26



ribosomal protein L26



chr16_+_96467606 1.305 ENSMUST00000061739.8
Pcp4
Purkinje cell protein 4
chr7_+_44896125 1.303 ENSMUST00000166552.1
ENSMUST00000168207.1
Fuz

fuzzy homolog (Drosophila)

chr7_+_44896077 1.299 ENSMUST00000071207.7
ENSMUST00000166849.1
ENSMUST00000168712.1
ENSMUST00000168389.1
Fuz



fuzzy homolog (Drosophila)



chr19_+_7417586 1.297 ENSMUST00000159348.1
2700081O15Rik
RIKEN cDNA 2700081O15 gene
chr14_+_57999305 1.296 ENSMUST00000180534.1
3110083C13Rik
RIKEN cDNA 3110083C13 gene
chr5_+_64160207 1.281 ENSMUST00000101195.2
Tbc1d1
TBC1 domain family, member 1
chr19_-_28963863 1.279 ENSMUST00000161813.1
4430402I18Rik
RIKEN cDNA 4430402I18 gene
chr6_-_137169710 1.276 ENSMUST00000117919.1
Rerg
RAS-like, estrogen-regulated, growth-inhibitor
chr18_+_73863672 1.273 ENSMUST00000134847.1
Mro
maestro
chr13_-_54565299 1.273 ENSMUST00000153065.1
ENSMUST00000126295.1
ENSMUST00000143144.1
ENSMUST00000132136.1
4833439L19Rik



RIKEN cDNA 4833439L19 gene



chr5_+_36484578 1.273 ENSMUST00000060100.1
Ccdc96
coiled-coil domain containing 96
chr4_-_137796350 1.249 ENSMUST00000030551.4
Alpl
alkaline phosphatase, liver/bone/kidney
chr5_-_137502402 1.248 ENSMUST00000111035.1
ENSMUST00000031728.4
Pop7

processing of precursor 7, ribonuclease P family, (S. cerevisiae)

chr1_+_34459746 1.233 ENSMUST00000027302.7
Ptpn18
protein tyrosine phosphatase, non-receptor type 18
chr15_-_76511951 1.196 ENSMUST00000023214.4
Dgat1
diacylglycerol O-acyltransferase 1
chr12_+_24708984 1.179 ENSMUST00000154588.1
Rrm2
ribonucleotide reductase M2
chr3_+_135281221 1.179 ENSMUST00000120397.1
ENSMUST00000171974.1
ENSMUST00000029817.7
Bdh2


3-hydroxybutyrate dehydrogenase, type 2


chr13_-_53286052 1.174 ENSMUST00000021918.8
Ror2
receptor tyrosine kinase-like orphan receptor 2
chr19_-_24280551 1.144 ENSMUST00000081333.4
Fxn
frataxin
chr6_+_120836201 1.141 ENSMUST00000009256.2
Bcl2l13
BCL2-like 13 (apoptosis facilitator)
chr2_+_165655237 1.132 ENSMUST00000063433.7
Eya2
eyes absent 2 homolog (Drosophila)
chr5_+_149678224 1.126 ENSMUST00000100404.3
B3galtl
beta 1,3-galactosyltransferase-like
chr5_+_64159429 1.124 ENSMUST00000043893.6
Tbc1d1
TBC1 domain family, member 1
chr7_-_139616309 1.123 ENSMUST00000166503.1
ENSMUST00000093991.3
E030019B06Rik

RIKEN cDNA E030019B06 gene

chr8_-_69890967 1.121 ENSMUST00000152938.1
Yjefn3
YjeF N-terminal domain containing 3
chr18_+_12643329 1.119 ENSMUST00000025294.7
Ttc39c
tetratricopeptide repeat domain 39C
chr3_-_95142346 1.116 ENSMUST00000013851.3
Tnfaip8l2
tumor necrosis factor, alpha-induced protein 8-like 2
chr10_+_94036001 1.107 ENSMUST00000020208.4
Fgd6
FYVE, RhoGEF and PH domain containing 6
chr18_-_3281036 1.078 ENSMUST00000049942.6
ENSMUST00000139537.1
ENSMUST00000124747.1
Crem


cAMP responsive element modulator


chr4_+_155831272 1.075 ENSMUST00000139651.1
ENSMUST00000084097.5
Aurkaip1

aurora kinase A interacting protein 1

chr19_-_10880370 1.066 ENSMUST00000133303.1
Tmem109
transmembrane protein 109
chr19_+_40612392 1.065 ENSMUST00000134063.1
Entpd1
ectonucleoside triphosphate diphosphohydrolase 1
chr2_+_19344820 1.060 ENSMUST00000150514.1
ENSMUST00000136456.1
4930447M23Rik

RIKEN cDNA 4930447M23 gene

chr8_+_40926220 1.057 ENSMUST00000034004.9
Pdgfrl
platelet-derived growth factor receptor-like
chr1_+_172481788 1.051 ENSMUST00000127052.1
Igsf9
immunoglobulin superfamily, member 9
chr13_-_54565368 1.050 ENSMUST00000026989.8
4833439L19Rik
RIKEN cDNA 4833439L19 gene
chr2_-_122369130 1.050 ENSMUST00000151130.1
ENSMUST00000125826.1
Shf

Src homology 2 domain containing F

chr2_+_167688915 1.047 ENSMUST00000070642.3
Cebpb
CCAAT/enhancer binding protein (C/EBP), beta
chr1_+_161969284 1.041 ENSMUST00000160881.1
ENSMUST00000159648.1
Pigc

phosphatidylinositol glycan anchor biosynthesis, class C

chr11_+_61956779 1.039 ENSMUST00000049836.7
Specc1
sperm antigen with calponin homology and coiled-coil domains 1
chr11_+_78178105 1.031 ENSMUST00000147819.1
Tlcd1
TLC domain containing 1
chr3_+_89246397 1.030 ENSMUST00000168900.1
Krtcap2
keratinocyte associated protein 2
chr12_+_24708241 1.023 ENSMUST00000020980.5
Rrm2
ribonucleotide reductase M2
chr1_+_172482199 1.022 ENSMUST00000135267.1
ENSMUST00000052629.6
ENSMUST00000111235.2
Igsf9


immunoglobulin superfamily, member 9


chr6_+_85154992 1.021 ENSMUST00000089584.5
Spr-ps1
sepiapterin reductase pseudogene 1
chr19_-_10240689 1.009 ENSMUST00000088013.5
Myrf
myelin regulatory factor
chr15_+_102470632 1.008 ENSMUST00000077037.5
ENSMUST00000078404.7
ENSMUST00000108838.3
Pcbp2


poly(rC) binding protein 2


chr8_+_92674289 1.007 ENSMUST00000034185.6
Irx6
Iroquois related homeobox 6 (Drosophila)
chr10_-_80577285 0.987 ENSMUST00000038558.8
Klf16
Kruppel-like factor 16
chr11_-_70982987 0.987 ENSMUST00000078528.6
C1qbp
complement component 1, q subcomponent binding protein
chr2_+_70661556 0.985 ENSMUST00000112201.1
ENSMUST00000028509.4
ENSMUST00000133432.1
ENSMUST00000112205.1
Gorasp2



golgi reassembly stacking protein 2



chr18_+_74216118 0.981 ENSMUST00000025444.6
Cxxc1
CXXC finger 1 (PHD domain)
chr17_+_29490812 0.976 ENSMUST00000024811.6
Pim1
proviral integration site 1
chr9_+_45906513 0.974 ENSMUST00000039059.6
Pcsk7
proprotein convertase subtilisin/kexin type 7
chr12_-_112674193 0.973 ENSMUST00000001780.3
Akt1
thymoma viral proto-oncogene 1
chr17_+_28232723 0.955 ENSMUST00000002320.8
Ppard
peroxisome proliferator activator receptor delta
chr14_+_77036746 0.951 ENSMUST00000048208.3
ENSMUST00000095625.4
Ccdc122

coiled-coil domain containing 122

chr6_-_85915653 0.928 ENSMUST00000161198.2
Cml1
camello-like 1
chr12_-_17176888 0.916 ENSMUST00000170580.1
Kcnf1
potassium voltage-gated channel, subfamily F, member 1
chr10_-_105841323 0.914 ENSMUST00000046638.9
Mettl25
methyltransferase like 25
chr10_+_121033960 0.908 ENSMUST00000020439.4
ENSMUST00000175867.1
Wif1

Wnt inhibitory factor 1

chr11_+_105975204 0.901 ENSMUST00000001964.7
Ace
angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
chr3_+_118562129 0.898 ENSMUST00000039177.7
Dpyd
dihydropyrimidine dehydrogenase
chr5_+_115559467 0.897 ENSMUST00000086519.5
Rplp0
ribosomal protein, large, P0
chr8_-_70873477 0.896 ENSMUST00000007865.5
Ccdc124
coiled-coil domain containing 124
chr13_-_55536504 0.896 ENSMUST00000021956.8
Ddx41
DEAD (Asp-Glu-Ala-Asp) box polypeptide 41
chr5_-_114128171 0.895 ENSMUST00000053657.6
ENSMUST00000112279.1
Alkbh2

alkB, alkylation repair homolog 2 (E. coli)

chr1_-_132367879 0.894 ENSMUST00000142609.1
Tmcc2
transmembrane and coiled-coil domains 2
chr11_+_98682554 0.893 ENSMUST00000017365.8
Psmd3
proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
chr5_+_115559505 0.888 ENSMUST00000156359.1
ENSMUST00000152976.1
Rplp0

ribosomal protein, large, P0

chr9_+_111439063 0.888 ENSMUST00000111879.3
Dclk3
doublecortin-like kinase 3
chr12_+_113156403 0.870 ENSMUST00000049271.8
4930427A07Rik
RIKEN cDNA 4930427A07 gene
chr5_+_107900859 0.868 ENSMUST00000153590.1
Rpl5
ribosomal protein L5
chr4_+_48540067 0.865 ENSMUST00000064807.2
Msantd3
Myb/SANT-like DNA-binding domain containing 3

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 8.0 GO:1903002 regulation of lipid transport across blood brain barrier(GO:1903000) positive regulation of lipid transport across blood brain barrier(GO:1903002)
2.5 7.6 GO:0009814 defense response, incompatible interaction(GO:0009814)
2.3 6.9 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) glycolytic process through fructose-1-phosphate(GO:0061625)
2.1 6.3 GO:0072382 minus-end-directed vesicle transport along microtubule(GO:0072382)
2.0 5.9 GO:0060598 dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis(GO:0060598)
1.7 5.1 GO:0060167 regulation of adenosine receptor signaling pathway(GO:0060167) regulation of G-protein coupled receptor internalization(GO:1904020)
1.1 3.4 GO:0070634 transepithelial ammonium transport(GO:0070634)
1.1 3.2 GO:0018199 peptidyl-glutamine modification(GO:0018199)
1.0 7.7 GO:0000050 urea cycle(GO:0000050) urea metabolic process(GO:0019627)
1.0 2.9 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.9 3.6 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.9 4.5 GO:0019236 response to pheromone(GO:0019236)
0.9 2.6 GO:2000314 negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.8 2.4 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.7 2.9 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.7 7.5 GO:0032825 positive regulation of natural killer cell differentiation(GO:0032825)
0.7 2.0 GO:0072076 nephrogenic mesenchyme development(GO:0072076)
0.6 1.8 GO:0046061 dATP catabolic process(GO:0046061)
0.6 1.7 GO:1902071 positive regulation of cellular response to hypoxia(GO:1900039) regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.5 3.2 GO:0003350 pulmonary myocardium development(GO:0003350)
0.5 2.2 GO:0006776 vitamin A metabolic process(GO:0006776)
0.5 1.6 GO:0010533 regulation of activation of Janus kinase activity(GO:0010533)
0.5 1.5 GO:0036233 glycine import(GO:0036233)
0.5 1.0 GO:2000510 positive regulation of dendritic cell chemotaxis(GO:2000510)
0.5 2.5 GO:1903232 melanosome assembly(GO:1903232)
0.5 2.5 GO:0003105 negative regulation of glomerular filtration(GO:0003105) positive regulation of NAD(P)H oxidase activity(GO:0033864) positive regulation of toll-like receptor 2 signaling pathway(GO:0034137)
0.5 1.9 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.5 1.4 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630) positive regulation of aminoacyl-tRNA ligase activity(GO:1903632) regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.5 2.8 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.4 1.8 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.4 1.8 GO:0031161 phosphatidylinositol catabolic process(GO:0031161)
0.4 1.3 GO:1902162 regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162)
0.4 2.8 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.4 1.2 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.4 2.3 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.4 3.3 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.4 2.5 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.3 2.4 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.3 1.4 GO:0010891 negative regulation of sequestering of triglyceride(GO:0010891) positive regulation of triglyceride catabolic process(GO:0010898)
0.3 2.0 GO:0032202 telomere assembly(GO:0032202)
0.3 0.7 GO:0032493 response to bacterial lipoprotein(GO:0032493)
0.3 1.0 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.3 3.0 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.3 1.6 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.3 1.3 GO:0060709 glycogen cell differentiation involved in embryonic placenta development(GO:0060709)
0.3 1.9 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.3 0.9 GO:2000170 positive regulation of peptidyl-cysteine S-nitrosylation(GO:2000170)
0.3 0.9 GO:0046104 thymidine metabolic process(GO:0046104) deoxyribonucleoside catabolic process(GO:0046121)
0.3 1.1 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.3 2.3 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.3 1.6 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.3 0.5 GO:0090202 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.3 1.3 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.3 0.8 GO:0002432 granuloma formation(GO:0002432)
0.2 0.7 GO:0036090 cleavage furrow ingression(GO:0036090)
0.2 2.9 GO:0001779 natural killer cell differentiation(GO:0001779)
0.2 2.9 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.2 3.5 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.2 1.2 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223) regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.2 1.4 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.2 0.7 GO:0042097 interleukin-4 biosynthetic process(GO:0042097) regulation of interleukin-4 biosynthetic process(GO:0045402)
0.2 1.1 GO:0019230 proprioception(GO:0019230)
0.2 1.6 GO:0048318 axial mesoderm development(GO:0048318)
0.2 1.8 GO:0051503 adenine nucleotide transport(GO:0051503)
0.2 4.2 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.2 4.0 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.2 1.5 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.2 2.7 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.2 0.6 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.2 0.8 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.2 0.6 GO:0035799 ureter maturation(GO:0035799)
0.2 0.8 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.2 1.0 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.2 0.9 GO:0035511 oxidative DNA demethylation(GO:0035511)
0.2 1.1 GO:2001170 negative regulation of ATP biosynthetic process(GO:2001170)
0.2 0.7 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.2 1.7 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.2 1.0 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.2 0.3 GO:0003383 apical constriction(GO:0003383)
0.2 0.5 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.2 0.8 GO:0032364 oxygen homeostasis(GO:0032364)
0.2 1.7 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.2 0.8 GO:0002667 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) negative regulation of protein kinase C signaling(GO:0090038)
0.1 0.4 GO:0015886 heme transport(GO:0015886)
0.1 1.1 GO:0016576 histone dephosphorylation(GO:0016576)
0.1 1.0 GO:2000138 positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
0.1 0.5 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
0.1 1.6 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.1 1.3 GO:0033603 positive regulation of dopamine secretion(GO:0033603)
0.1 1.9 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.1 0.4 GO:0060160 negative regulation of dopamine receptor signaling pathway(GO:0060160)
0.1 1.6 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.1 0.5 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.1 2.2 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.1 1.3 GO:0060253 negative regulation of glial cell proliferation(GO:0060253)
0.1 0.2 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100)
0.1 2.6 GO:0001539 cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285)
0.1 2.5 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1 1.4 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.1 0.7 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.1 1.3 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.1 1.3 GO:0044406 adhesion of symbiont to host(GO:0044406)
0.1 0.8 GO:0015670 carbon dioxide transport(GO:0015670)
0.1 1.5 GO:0032288 myelin assembly(GO:0032288)
0.1 0.3 GO:0021759 globus pallidus development(GO:0021759)
0.1 0.7 GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.1 2.5 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.1 0.3 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.1 0.9 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.1 0.6 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 0.7 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.1 0.4 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.1 0.3 GO:0032439 endosome localization(GO:0032439)
0.1 2.0 GO:0044550 secondary metabolite biosynthetic process(GO:0044550)
0.1 1.1 GO:0002467 germinal center formation(GO:0002467)
0.1 3.0 GO:0007131 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.1 0.7 GO:0006228 UTP biosynthetic process(GO:0006228)
0.1 0.2 GO:0072319 abscission(GO:0009838) vesicle uncoating(GO:0072319) positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.1 0.5 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.1 0.3 GO:0002755 MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
0.1 0.4 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1 0.4 GO:0003431 growth plate cartilage chondrocyte differentiation(GO:0003418) growth plate cartilage chondrocyte development(GO:0003431)
0.1 5.3 GO:0051865 protein autoubiquitination(GO:0051865)
0.1 0.2 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.1 3.7 GO:0051290 protein heterotetramerization(GO:0051290)
0.1 1.8 GO:0071353 response to interleukin-4(GO:0070670) cellular response to interleukin-4(GO:0071353)
0.1 3.4 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.1 0.8 GO:0010825 positive regulation of centrosome duplication(GO:0010825)
0.1 2.3 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.1 2.0 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.1 3.3 GO:0071277 cellular response to calcium ion(GO:0071277)
0.1 0.8 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.1 0.8 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.1 0.2 GO:1900864 tRNA wobble position uridine thiolation(GO:0002143) mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.1 0.3 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.1 0.3 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.1 0.4 GO:0070423 nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431)
0.1 0.2 GO:0006083 acetate metabolic process(GO:0006083)
0.1 0.6 GO:0036296 cellular response to increased oxygen levels(GO:0036295) response to increased oxygen levels(GO:0036296)
0.1 0.8 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.3 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
0.0 0.6 GO:0045351 type I interferon biosynthetic process(GO:0045351)
0.0 0.3 GO:1904355 positive regulation of telomere capping(GO:1904355)
0.0 2.9 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.5 GO:0032402 melanosome transport(GO:0032402)
0.0 0.6 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 2.0 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.0 0.3 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 2.4 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.5 GO:0090201 negative regulation of release of cytochrome c from mitochondria(GO:0090201)
0.0 1.6 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.2 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.3 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 1.1 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.0 0.6 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.1 GO:0006751 glutathione catabolic process(GO:0006751)
0.0 0.2 GO:0006621 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0 0.2 GO:0046645 positive regulation of gamma-delta T cell differentiation(GO:0045588) positive regulation of gamma-delta T cell activation(GO:0046645)
0.0 0.6 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.7 GO:0034389 lipid particle organization(GO:0034389)
0.0 1.1 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 1.2 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 1.8 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.0 0.5 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.9 GO:0032933 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.7 GO:0014002 astrocyte development(GO:0014002)
0.0 0.1 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
0.0 0.2 GO:0072086 specification of loop of Henle identity(GO:0072086)
0.0 0.1 GO:1903207 neuron death in response to hydrogen peroxide(GO:0036476) regulation of hydrogen peroxide-induced neuron death(GO:1903207) negative regulation of hydrogen peroxide-induced neuron death(GO:1903208)
0.0 0.2 GO:0001980 regulation of systemic arterial blood pressure by ischemic conditions(GO:0001980)
0.0 0.7 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.0 1.1 GO:0031648 protein destabilization(GO:0031648)
0.0 1.3 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.7 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.6 GO:0030262 apoptotic nuclear changes(GO:0030262)
0.0 0.3 GO:0019985 translesion synthesis(GO:0019985)
0.0 1.3 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.3 GO:0033273 response to vitamin(GO:0033273)
0.0 0.9 GO:0042491 auditory receptor cell differentiation(GO:0042491)
0.0 0.9 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 2.5 GO:2001235 positive regulation of apoptotic signaling pathway(GO:2001235)
0.0 0.1 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.0 0.3 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0 0.8 GO:0018279 peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.2 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.9 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.0 0.1 GO:0060431 primary lung bud formation(GO:0060431)
0.0 0.5 GO:0061036 positive regulation of cartilage development(GO:0061036)
0.0 0.2 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 1.1 GO:0050868 negative regulation of T cell activation(GO:0050868)
0.0 0.4 GO:0000469 cleavage involved in rRNA processing(GO:0000469)
0.0 0.1 GO:0072718 response to cisplatin(GO:0072718)
0.0 1.5 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.1 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.7 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.3 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.3 GO:0031297 replication fork processing(GO:0031297)
0.0 0.5 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.5 GO:0038202 TORC1 signaling(GO:0038202)
0.0 0.2 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.0 0.1 GO:0051014 actin filament severing(GO:0051014)
0.0 0.2 GO:0003351 epithelial cilium movement(GO:0003351)
0.0 0.9 GO:1900181 negative regulation of protein localization to nucleus(GO:1900181)
0.0 0.8 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 0.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.7 GO:0030593 neutrophil chemotaxis(GO:0030593)
0.0 0.1 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.0 0.1 GO:0070266 necroptotic process(GO:0070266)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 8.0 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
2.3 6.9 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.8 4.7 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.7 2.0 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.5 2.5 GO:0043020 NADPH oxidase complex(GO:0043020)
0.5 1.5 GO:0071438 integrin alpha3-beta1 complex(GO:0034667) invadopodium membrane(GO:0071438)
0.5 1.4 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.4 2.2 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.4 1.6 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.4 4.7 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.4 0.7 GO:0034679 integrin alpha9-beta1 complex(GO:0034679)
0.3 8.6 GO:0005921 gap junction(GO:0005921)
0.3 2.0 GO:0045179 apical cortex(GO:0045179)
0.3 1.6 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.3 3.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.3 6.3 GO:0031616 spindle pole centrosome(GO:0031616)
0.3 1.4 GO:1990131 Iml1 complex(GO:1990130) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.2 1.7 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.2 1.2 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.2 1.8 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.2 1.6 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.2 1.9 GO:1990023 mitotic spindle midzone(GO:1990023)
0.2 2.8 GO:0032593 insulin-responsive compartment(GO:0032593)
0.2 1.1 GO:0097452 GAIT complex(GO:0097452)
0.2 0.8 GO:0097361 CIA complex(GO:0097361)
0.2 2.6 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.1 1.9 GO:0070852 cell body fiber(GO:0070852)
0.1 1.3 GO:0005883 neurofilament(GO:0005883)
0.1 1.5 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 3.1 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 8.5 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 6.3 GO:0045171 intercellular bridge(GO:0045171)
0.1 1.4 GO:0005687 U4 snRNP(GO:0005687)
0.1 0.4 GO:0030677 ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.1 0.7 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 0.5 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 0.3 GO:0035101 FACT complex(GO:0035101)
0.1 0.7 GO:0070187 telosome(GO:0070187)
0.1 0.7 GO:0042825 TAP complex(GO:0042825)
0.1 4.0 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 1.6 GO:0097225 sperm midpiece(GO:0097225)
0.1 5.0 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 2.0 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 1.6 GO:0001891 phagocytic cup(GO:0001891)
0.1 0.7 GO:0000813 ESCRT I complex(GO:0000813)
0.1 3.0 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 3.6 GO:0032420 stereocilium(GO:0032420)
0.1 0.5 GO:0097255 R2TP complex(GO:0097255)
0.1 0.7 GO:0016272 prefoldin complex(GO:0016272)
0.1 0.5 GO:0071203 WASH complex(GO:0071203)
0.1 1.5 GO:0016580 Sin3 complex(GO:0016580)
0.1 0.8 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 1.1 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 4.7 GO:0005844 polysome(GO:0005844)
0.1 0.8 GO:0030057 desmosome(GO:0030057)
0.1 1.5 GO:0043218 compact myelin(GO:0043218)
0.1 0.8 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1 5.1 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.1 0.4 GO:0030914 STAGA complex(GO:0030914)
0.1 0.7 GO:0002080 acrosomal membrane(GO:0002080)
0.1 1.1 GO:0005605 basal lamina(GO:0005605)
0.1 5.5 GO:0072562 blood microparticle(GO:0072562)
0.1 2.1 GO:0060077 inhibitory synapse(GO:0060077)
0.1 0.3 GO:0070876 SOSS complex(GO:0070876)
0.1 0.8 GO:0005869 dynactin complex(GO:0005869)
0.1 0.5 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 3.7 GO:0045178 basal part of cell(GO:0045178)
0.1 0.5 GO:0031931 TORC1 complex(GO:0031931)
0.1 0.6 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.1 0.8 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 1.2 GO:0031082 BLOC complex(GO:0031082)
0.0 0.7 GO:0070938 contractile ring(GO:0070938)
0.0 0.3 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 4.9 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.2 GO:1990584 cardiac Troponin complex(GO:1990584)
0.0 1.4 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.9 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.3 GO:0031933 telomeric heterochromatin(GO:0031933)
0.0 1.3 GO:0043034 costamere(GO:0043034)
0.0 0.2 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 1.3 GO:0001772 immunological synapse(GO:0001772)
0.0 0.2 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.8 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 1.4 GO:0015030 Cajal body(GO:0015030)
0.0 1.3 GO:0044429 mitochondrial envelope(GO:0005740) mitochondrial part(GO:0044429)
0.0 0.5 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.2 GO:0090543 Flemming body(GO:0090543)
0.0 1.8 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.4 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 5.6 GO:0001726 ruffle(GO:0001726)
0.0 0.3 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.4 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.4 GO:1990635 proximal dendrite(GO:1990635)
0.0 1.5 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.4 GO:0030125 clathrin vesicle coat(GO:0030125)
0.0 0.4 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.1 GO:1990037 Lewy body core(GO:1990037)
0.0 1.9 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.3 GO:0031105 septin complex(GO:0031105)
0.0 0.2 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.1 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.0 0.3 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 1.3 GO:0005811 lipid particle(GO:0005811)
0.0 0.5 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 3.7 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 1.4 GO:0005840 ribosome(GO:0005840)
0.0 0.3 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.5 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.0 0.1 GO:0070069 cytochrome complex(GO:0070069)
0.0 0.3 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.7 GO:0031519 PcG protein complex(GO:0031519)
0.0 6.0 GO:0005667 transcription factor complex(GO:0005667)
0.0 3.3 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 0.5 GO:1990391 DNA repair complex(GO:1990391)
0.0 1.1 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 1.3 GO:0031514 motile cilium(GO:0031514)
0.0 1.5 GO:0036064 ciliary basal body(GO:0036064)
0.0 4.0 GO:0019866 mitochondrial inner membrane(GO:0005743) organelle inner membrane(GO:0019866)
0.0 1.4 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.6 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.2 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 3.2 GO:0005925 focal adhesion(GO:0005925)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 8.0 GO:0046911 hydroxyapatite binding(GO:0046848) metal chelating activity(GO:0046911) phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
2.3 6.9 GO:0004454 ketohexokinase activity(GO:0004454)
1.3 5.1 GO:0031687 A2A adenosine receptor binding(GO:0031687)
1.1 4.3 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.8 3.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.7 2.9 GO:0004921 interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970)
0.7 2.0 GO:0035651 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.7 7.3 GO:0019992 diacylglycerol binding(GO:0019992)
0.6 3.7 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.6 2.5 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.6 1.8 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.5 2.5 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.5 3.0 GO:0043426 MRF binding(GO:0043426)
0.5 1.9 GO:0016842 amidine-lyase activity(GO:0016842)
0.4 6.3 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.4 1.3 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.4 2.2 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.4 1.3 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.4 3.8 GO:0005523 tropomyosin binding(GO:0005523)
0.4 1.2 GO:0098973 structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.4 5.8 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013)
0.3 1.0 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.3 1.0 GO:0016501 prostacyclin receptor activity(GO:0016501)
0.3 0.9 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
0.3 1.2 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.3 0.9 GO:0051747 cytosine C-5 DNA demethylase activity(GO:0051747)
0.3 1.6 GO:0051525 NFAT protein binding(GO:0051525)
0.3 2.9 GO:0070569 uridylyltransferase activity(GO:0070569)
0.3 1.5 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.2 1.0 GO:0030984 kininogen binding(GO:0030984)
0.2 2.3 GO:0001727 lipid kinase activity(GO:0001727)
0.2 1.1 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.2 0.9 GO:0070573 tripeptidyl-peptidase activity(GO:0008240) metallodipeptidase activity(GO:0070573)
0.2 1.7 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.2 0.6 GO:0019966 interleukin-1 binding(GO:0019966)
0.2 1.4 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.2 1.6 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.2 1.8 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.2 0.8 GO:0035473 lipase binding(GO:0035473)
0.2 3.4 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.2 1.2 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.2 1.0 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.2 3.0 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.2 3.0 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.2 0.8 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.2 0.8 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.2 1.0 GO:0045322 unmethylated CpG binding(GO:0045322)
0.2 3.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.2 1.0 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.2 1.7 GO:0004526 ribonuclease P activity(GO:0004526)
0.2 2.0 GO:0008301 DNA binding, bending(GO:0008301)
0.2 1.4 GO:1990446 U1 snRNP binding(GO:1990446)
0.1 1.0 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.9 GO:0002054 nucleobase binding(GO:0002054)
0.1 0.4 GO:0015232 heme transporter activity(GO:0015232)
0.1 1.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 3.2 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 1.3 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.1 2.3 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.1 0.4 GO:0031750 D3 dopamine receptor binding(GO:0031750)
0.1 0.6 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1 5.7 GO:0030332 cyclin binding(GO:0030332)
0.1 4.4 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 1.4 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 0.7 GO:0046978 TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.1 1.1 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
0.1 0.8 GO:0051879 Hsp90 protein binding(GO:0051879)
0.1 1.9 GO:0035198 miRNA binding(GO:0035198)
0.1 1.3 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.1 1.1 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 1.5 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.1 1.8 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 2.9 GO:0043236 laminin binding(GO:0043236)
0.1 0.5 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1 1.4 GO:0070034 telomerase RNA binding(GO:0070034)
0.1 2.1 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.1 0.3 GO:0008802 betaine-aldehyde dehydrogenase activity(GO:0008802)
0.1 14.4 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 1.0 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 1.9 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 3.0 GO:0005507 copper ion binding(GO:0005507)
0.1 0.2 GO:0042610 CD8 receptor binding(GO:0042610)
0.1 0.6 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 2.5 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 0.5 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 0.7 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.1 2.3 GO:0005112 Notch binding(GO:0005112)
0.1 0.8 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 0.6 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.1 0.2 GO:0030172 troponin C binding(GO:0030172)
0.1 0.8 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 1.9 GO:0003954 NADH dehydrogenase activity(GO:0003954)
0.1 5.4 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.1 0.2 GO:0046923 ER retention sequence binding(GO:0046923)
0.1 0.2 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.1 1.6 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.1 1.8 GO:0031369 translation initiation factor binding(GO:0031369)
0.1 0.8 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.2 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.1 0.2 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.1 0.3 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.2 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.6 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 1.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.9 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.3 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.0 0.7 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.6 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.1 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.0 1.5 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.1 GO:0004477 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.0 0.3 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.5 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 2.7 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 3.5 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.0 2.5 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.3 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 0.2 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.2 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 0.2 GO:0048256 flap endonuclease activity(GO:0048256)
0.0 10.6 GO:0005525 GTP binding(GO:0005525)
0.0 0.9 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.6 GO:0001047 core promoter binding(GO:0001047)
0.0 1.7 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.6 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.5 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.2 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.3 GO:0005537 mannose binding(GO:0005537)
0.0 0.6 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 3.6 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 1.2 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.3 GO:0051400 BH domain binding(GO:0051400)
0.0 3.3 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.1 GO:0008242 omega peptidase activity(GO:0008242)
0.0 0.8 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.9 GO:0032934 cholesterol binding(GO:0015485) sterol binding(GO:0032934)
0.0 0.5 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.2 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.1 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.0 0.3 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.2 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 1.0 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.5 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.7 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.0 0.1 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.4 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.4 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 1.0 GO:0004004 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.5 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 3.5 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.5 GO:0030507 spectrin binding(GO:0030507)
0.0 0.1 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.5 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 1.7 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.5 GO:0046332 SMAD binding(GO:0046332)
0.0 1.1 GO:0051117 ATPase binding(GO:0051117)
0.0 1.2 GO:0005125 cytokine activity(GO:0005125)
0.0 0.0 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.9 GO:0051087 chaperone binding(GO:0051087)
0.0 0.4 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.8 GO:0019902 phosphatase binding(GO:0019902)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 5.2 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.2 8.2 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.2 5.9 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.2 4.2 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.1 3.5 PID_PRL_SIGNALING_EVENTS_PATHWAY Signaling events mediated by PRL
0.1 8.0 ST_T_CELL_SIGNAL_TRANSDUCTION T Cell Signal Transduction
0.1 8.5 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 0.9 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 1.0 PID_IL5_PATHWAY IL5-mediated signaling events
0.1 1.9 PID_AR_NONGENOMIC_PATHWAY Nongenotropic Androgen signaling
0.1 3.2 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 3.2 PID_IL4_2PATHWAY IL4-mediated signaling events
0.1 3.7 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.1 2.1 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.1 2.6 PID_FAK_PATHWAY Signaling events mediated by focal adhesion kinase
0.1 1.7 PID_AURORA_A_PATHWAY Aurora A signaling
0.1 1.7 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.1 1.5 PID_A6B1_A6B4_INTEGRIN_PATHWAY a6b1 and a6b4 Integrin signaling
0.0 1.5 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 5.4 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.8 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 3.4 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.1 PID_TCR_JNK_PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 2.2 PID_E2F_PATHWAY E2F transcription factor network
0.0 0.9 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.0 0.2 ST_TYPE_I_INTERFERON_PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.5 PID_PI3KCI_AKT_PATHWAY Class I PI3K signaling events mediated by Akt
0.0 3.7 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.0 PID_PS1_PATHWAY Presenilin action in Notch and Wnt signaling
0.0 1.3 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.0 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.0 1.4 PID_P53_REGULATION_PATHWAY p53 pathway
0.0 1.8 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.6 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.2 PID_CXCR4_PATHWAY CXCR4-mediated signaling events
0.0 1.0 PID_P73PATHWAY p73 transcription factor network
0.0 0.3 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.0 0.3 SIG_CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.7 PID_TELOMERASE_PATHWAY Regulation of Telomerase
0.0 0.2 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.0 0.3 PID_FANCONI_PATHWAY Fanconi anemia pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 8.5 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.3 4.7 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.2 3.5 REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.2 1.8 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.2 2.4 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.2 4.3 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.2 3.4 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.2 5.5 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.2 3.7 REACTOME_HOST_INTERACTIONS_OF_HIV_FACTORS Genes involved in Host Interactions of HIV factors
0.2 4.5 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA Genes involved in G beta:gamma signalling through PLC beta
0.1 1.6 REACTOME_REGULATION_OF_IFNG_SIGNALING Genes involved in Regulation of IFNG signaling
0.1 0.7 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.1 1.0 REACTOME_PD1_SIGNALING Genes involved in PD-1 signaling
0.1 3.5 REACTOME_KINESINS Genes involved in Kinesins
0.1 4.0 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 1.0 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 1.8 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 2.2 REACTOME_G1_S_SPECIFIC_TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.1 3.0 REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 11.7 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.1 1.0 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.1 0.9 REACTOME_PYRIMIDINE_CATABOLISM Genes involved in Pyrimidine catabolism
0.1 1.6 REACTOME_ARMS_MEDIATED_ACTIVATION Genes involved in ARMS-mediated activation
0.1 0.7 REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.1 0.8 REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 1.7 REACTOME_RIP_MEDIATED_NFKB_ACTIVATION_VIA_DAI Genes involved in RIP-mediated NFkB activation via DAI
0.1 1.0 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 1.3 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.1 0.3 REACTOME_INHIBITION_OF_REPLICATION_INITIATION_OF_DAMAGED_DNA_BY_RB1_E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.1 0.6 REACTOME_FRS2_MEDIATED_CASCADE Genes involved in FRS2-mediated cascade
0.1 1.9 REACTOME_EXTENSION_OF_TELOMERES Genes involved in Extension of Telomeres
0.1 1.1 REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS Genes involved in Activation of BH3-only proteins
0.1 2.1 REACTOME_BASIGIN_INTERACTIONS Genes involved in Basigin interactions
0.1 2.7 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.1 0.3 REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX_UPON_TLR7_8_OR_9_STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 1.3 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.7 REACTOME_SIGNAL_TRANSDUCTION_BY_L1 Genes involved in Signal transduction by L1
0.0 1.4 REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 2.2 REACTOME_MEIOTIC_RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.2 REACTOME_ETHANOL_OXIDATION Genes involved in Ethanol oxidation
0.0 1.3 REACTOME_G1_PHASE Genes involved in G1 Phase
0.0 2.4 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 3.4 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.8 REACTOME_CA_DEPENDENT_EVENTS Genes involved in Ca-dependent events
0.0 1.1 REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 1.5 REACTOME_MRNA_SPLICING_MINOR_PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 2.0 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.0 0.4 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.5 REACTOME_CD28_DEPENDENT_PI3K_AKT_SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 0.4 REACTOME_P38MAPK_EVENTS Genes involved in p38MAPK events
0.0 0.6 REACTOME_INTERFERON_GAMMA_SIGNALING Genes involved in Interferon gamma signaling
0.0 0.3 REACTOME_REGULATION_OF_WATER_BALANCE_BY_RENAL_AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 1.2 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 1.3 REACTOME_GLUCOSE_METABOLISM Genes involved in Glucose metabolism
0.0 1.7 REACTOME_GLYCEROPHOSPHOLIPID_BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 0.2 REACTOME_METABOLISM_OF_NON_CODING_RNA Genes involved in Metabolism of non-coding RNA
0.0 0.8 REACTOME_CDK_MEDIATED_PHOSPHORYLATION_AND_REMOVAL_OF_CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.0 0.1 REACTOME_G_PROTEIN_ACTIVATION Genes involved in G-protein activation
0.0 1.0 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.7 REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES Genes involved in Metabolism of amino acids and derivatives