Motif ID: Rarb

Z-value: 0.526


Transcription factors associated with Rarb:

Gene SymbolEntrez IDGene Name
Rarb ENSMUSG00000017491.8 Rarb

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Rarbmm10_v2_chr14_-_16575456_16575501-0.075.6e-01Click!


Activity profile for motif Rarb.

activity profile for motif Rarb


Sorted Z-values histogram for motif Rarb

Sorted Z-values for motif Rarb



Network of associatons between targets according to the STRING database.



First level regulatory network of Rarb

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_116031047 11.379 ENSMUST00000106612.1
 Sox6
SRY-box containing gene 6
chr1_+_90203980 10.422 ENSMUST00000065587.4
ENSMUST00000159654.1
 Ackr3

atypical chemokine receptor 3

chr3_+_88081997 10.121 ENSMUST00000071812.5
 Iqgap3
IQ motif containing GTPase activating protein 3
chr1_+_191821444 7.851 ENSMUST00000027931.7
 Nek2
NIMA (never in mitosis gene a)-related expressed kinase 2
chr5_+_92897981 7.386 ENSMUST00000113051.2
 Shroom3
shroom family member 3
chr3_-_52104891 7.329 ENSMUST00000121440.1
 Maml3
mastermind like 3 (Drosophila)
chr10_-_92722356 4.366 ENSMUST00000020163.6
 Nedd1
neural precursor cell expressed, developmentally down-regulated gene 1
chr2_-_163417092 2.876 ENSMUST00000127038.1
 Oser1
oxidative stress responsive serine rich 1
chr1_+_4807823 2.547 ENSMUST00000027036.4
ENSMUST00000119612.2
ENSMUST00000137887.1
ENSMUST00000115529.1
ENSMUST00000150971.1
 Lypla1




lysophospholipase 1




chr18_+_65582390 1.961 ENSMUST00000169679.1
ENSMUST00000183326.1
 Zfp532

zinc finger protein 532

chr2_+_30281043 1.635 ENSMUST00000143119.2
 RP23-395P6.9
RP23-395P6.9
chr15_-_98662858 1.553 ENSMUST00000162384.1
ENSMUST00000003450.8
 Ddx23

DEAD (Asp-Glu-Ala-Asp) box polypeptide 23

chr16_+_38346986 1.382 ENSMUST00000050273.8
ENSMUST00000120495.1
ENSMUST00000119704.1
 Cox17

Gm21987
cytochrome c oxidase assembly protein 17

predicted gene 21987
chr7_+_108934405 1.272 ENSMUST00000033342.6
 Eif3f
eukaryotic translation initiation factor 3, subunit F
chr7_+_127904079 0.888 ENSMUST00000071056.7
 Bckdk
branched chain ketoacid dehydrogenase kinase
chr1_+_24177610 0.691 ENSMUST00000054588.8
 Col9a1
collagen, type IX, alpha 1
chr19_-_8786272 0.571 ENSMUST00000176610.1
ENSMUST00000177056.1
 Taf6l

TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor

chr8_+_106683052 0.474 ENSMUST00000048359.4
 Tango6
transport and golgi organization 6
chr19_-_8786245 0.426 ENSMUST00000177216.1
 Taf6l
TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor
chr10_+_43524080 0.357 ENSMUST00000057649.6
 Gm9803
predicted gene 9803
chr11_+_105178765 0.223 ENSMUST00000106939.2
 Tlk2
tousled-like kinase 2 (Arabidopsis)
chr3_+_108186332 0.151 ENSMUST00000050909.6
ENSMUST00000106659.2
ENSMUST00000106656.1
ENSMUST00000106661.2
 Amigo1



adhesion molecule with Ig like domain 1



chr19_-_8786408 0.012 ENSMUST00000176496.1
 Taf6l
TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 7.9 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
1.0 11.4 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
1.0 10.1 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.7 7.3 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.5 1.4 GO:1904959 regulation of electron carrier activity(GO:1904732) regulation of cytochrome-c oxidase activity(GO:1904959)
0.4 2.5 GO:0098734 protein depalmitoylation(GO:0002084) negative regulation of Golgi to plasma membrane protein transport(GO:0042997) negative regulation of establishment of protein localization to plasma membrane(GO:0090005) macromolecule depalmitoylation(GO:0098734)
0.3 10.4 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.1 4.4 GO:0071539 protein localization to centrosome(GO:0071539)
0.1 1.3 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.1 7.4 GO:0002066 columnar/cuboidal epithelial cell development(GO:0002066)
0.1 0.9 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 0.7 GO:0003417 growth plate cartilage development(GO:0003417)
0.0 2.9 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.0 1.6 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.2 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 1.0 GO:0043966 histone H3 acetylation(GO:0043966)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.4 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.2 0.9 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.2 0.7 GO:0005594 collagen type IX trimer(GO:0005594)
0.1 1.3 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 10.1 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 10.4 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 7.9 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.1 1.6 GO:0005682 U5 snRNP(GO:0005682)
0.1 7.4 GO:0043296 apical junction complex(GO:0043296)
0.0 1.0 GO:0030914 STAGA complex(GO:0030914)
0.0 11.4 GO:0005667 transcription factor complex(GO:0005667)
0.0 7.3 GO:0016607 nuclear speck(GO:0016607)
0.0 1.4 GO:0005758 mitochondrial intermembrane space(GO:0005758)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.5 10.4 GO:0016494 C-X-C chemokine receptor activity(GO:0016494) C-X-C chemokine binding(GO:0019958)
2.5 10.1 GO:0032027 myosin light chain binding(GO:0032027)
0.3 2.5 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.2 1.4 GO:0016531 copper chaperone activity(GO:0016531)
0.1 11.4 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 7.4 GO:0051015 actin filament binding(GO:0051015)
0.0 7.9 GO:0019903 protein phosphatase binding(GO:0019903)
0.0 1.3 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 8.3 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 1.6 GO:0004004 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 7.9 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.1 10.1 PID_RAC1_PATHWAY RAC1 signaling pathway
0.0 0.7 NABA_COLLAGENS Genes encoding collagen proteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.4 REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.4 7.3 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.3 7.9 REACTOME_APC_CDC20_MEDIATED_DEGRADATION_OF_NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.0 1.2 REACTOME_ENOS_ACTIVATION_AND_REGULATION Genes involved in eNOS activation and regulation
0.0 1.6 REACTOME_MRNA_SPLICING_MINOR_PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 1.4 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.0 1.3 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.7 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions