Motif ID: Rhox11
Z-value: 0.447
Transcription factors associated with Rhox11:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Rhox11 | ENSMUSG00000051038.9 | Rhox11 |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.2 | 3.6 | GO:1902071 | positive regulation of cellular response to hypoxia(GO:1900039) regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071) |
| 1.0 | 5.1 | GO:2000346 | negative regulation of hepatocyte proliferation(GO:2000346) |
| 1.0 | 5.8 | GO:0003350 | pulmonary myocardium development(GO:0003350) |
| 0.8 | 7.8 | GO:0033314 | mitotic DNA replication checkpoint(GO:0033314) |
| 0.4 | 2.1 | GO:1903566 | positive regulation of protein localization to cilium(GO:1903566) |
| 0.4 | 2.1 | GO:0032901 | positive regulation of neurotrophin production(GO:0032901) |
| 0.3 | 2.0 | GO:1904491 | protein localization to ciliary transition zone(GO:1904491) |
| 0.2 | 3.3 | GO:1902004 | positive regulation of beta-amyloid formation(GO:1902004) |
| 0.2 | 0.6 | GO:0038165 | oncostatin-M-mediated signaling pathway(GO:0038165) |
| 0.2 | 0.8 | GO:0014042 | positive regulation of neuron maturation(GO:0014042) |
| 0.2 | 1.5 | GO:0018344 | protein geranylgeranylation(GO:0018344) |
| 0.1 | 0.9 | GO:1903071 | positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071) |
| 0.1 | 0.6 | GO:0038018 | Wnt receptor catabolic process(GO:0038018) |
| 0.1 | 1.1 | GO:1902570 | protein localization to nucleolus(GO:1902570) |
| 0.1 | 1.1 | GO:1902083 | negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083) |
| 0.1 | 0.4 | GO:0006432 | phenylalanyl-tRNA aminoacylation(GO:0006432) |
| 0.1 | 0.5 | GO:0034720 | histone H3-K4 demethylation(GO:0034720) |
| 0.1 | 0.5 | GO:0034316 | negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316) |
| 0.1 | 0.9 | GO:2000381 | negative regulation of mesoderm development(GO:2000381) |
| 0.1 | 1.0 | GO:0032880 | regulation of protein localization(GO:0032880) |
| 0.0 | 2.9 | GO:0051489 | regulation of filopodium assembly(GO:0051489) |
| 0.0 | 0.2 | GO:0044351 | macropinocytosis(GO:0044351) |
| 0.0 | 0.4 | GO:0006968 | cellular defense response(GO:0006968) |
| 0.0 | 0.2 | GO:0003065 | positive regulation of heart rate by epinephrine(GO:0003065) |
| 0.0 | 2.0 | GO:0007338 | single fertilization(GO:0007338) |
| 0.0 | 0.2 | GO:0042730 | fibrinolysis(GO:0042730) |
| 0.0 | 2.0 | GO:0043473 | pigmentation(GO:0043473) |
| 0.0 | 2.1 | GO:0007631 | feeding behavior(GO:0007631) |
| 0.0 | 0.2 | GO:2001197 | regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197) |
| 0.0 | 0.4 | GO:0010842 | retina layer formation(GO:0010842) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 2.0 | GO:0031084 | BLOC-2 complex(GO:0031084) |
| 0.3 | 1.5 | GO:0005968 | Rab-protein geranylgeranyltransferase complex(GO:0005968) |
| 0.2 | 0.9 | GO:1990037 | Lewy body core(GO:1990037) |
| 0.1 | 0.8 | GO:0031314 | extrinsic component of mitochondrial inner membrane(GO:0031314) |
| 0.1 | 0.4 | GO:0009328 | phenylalanine-tRNA ligase complex(GO:0009328) |
| 0.0 | 2.9 | GO:0016459 | myosin complex(GO:0016459) |
| 0.0 | 2.0 | GO:0035869 | ciliary transition zone(GO:0035869) |
| 0.0 | 0.3 | GO:0070652 | HAUS complex(GO:0070652) |
| 0.0 | 4.2 | GO:0005814 | centriole(GO:0005814) |
| 0.0 | 0.2 | GO:0001739 | sex chromatin(GO:0001739) |
| 0.0 | 0.2 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) |
| 0.0 | 2.3 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.0 | 1.1 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
| 0.0 | 2.5 | GO:0000776 | kinetochore(GO:0000776) |
| 0.0 | 1.5 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
| 0.0 | 0.6 | GO:0032590 | dendrite membrane(GO:0032590) |
| 0.0 | 3.3 | GO:0005802 | trans-Golgi network(GO:0005802) |
| 0.0 | 0.2 | GO:0045180 | basal cortex(GO:0045180) |
| 0.0 | 5.1 | GO:0005911 | cell-cell junction(GO:0005911) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.3 | 7.8 | GO:0010997 | anaphase-promoting complex binding(GO:0010997) |
| 0.4 | 5.8 | GO:0038191 | neuropilin binding(GO:0038191) |
| 0.3 | 2.1 | GO:0048403 | brain-derived neurotrophic factor binding(GO:0048403) |
| 0.2 | 0.6 | GO:0004923 | leukemia inhibitory factor receptor activity(GO:0004923) oncostatin-M receptor activity(GO:0004924) |
| 0.2 | 1.1 | GO:0005087 | Ran guanyl-nucleotide exchange factor activity(GO:0005087) |
| 0.1 | 0.5 | GO:0034647 | histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647) |
| 0.1 | 0.3 | GO:0000253 | 3-keto sterol reductase activity(GO:0000253) |
| 0.1 | 0.8 | GO:1901612 | phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612) |
| 0.1 | 2.1 | GO:0043422 | protein kinase B binding(GO:0043422) |
| 0.1 | 0.4 | GO:0004826 | phenylalanine-tRNA ligase activity(GO:0004826) |
| 0.1 | 1.5 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
| 0.1 | 0.4 | GO:0046703 | natural killer cell lectin-like receptor binding(GO:0046703) |
| 0.1 | 3.3 | GO:0001540 | beta-amyloid binding(GO:0001540) |
| 0.1 | 2.9 | GO:0030507 | spectrin binding(GO:0030507) |
| 0.0 | 0.5 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
| 0.0 | 0.2 | GO:0097027 | ubiquitin-protein transferase activator activity(GO:0097027) |
| 0.0 | 2.5 | GO:0052689 | carboxylic ester hydrolase activity(GO:0052689) |
| 0.0 | 0.2 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) calcium-dependent protein kinase activity(GO:0010857) |
| 0.0 | 0.6 | GO:0005109 | frizzled binding(GO:0005109) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 10.3 | PID_PLK1_PATHWAY | PLK1 signaling events |
| 0.1 | 5.1 | PID_ILK_PATHWAY | Integrin-linked kinase signaling |
| 0.1 | 2.9 | PID_NETRIN_PATHWAY | Netrin-mediated signaling events |
| 0.0 | 5.8 | NABA_ECM_AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.0 | 0.2 | PID_INTEGRIN2_PATHWAY | Beta2 integrin cell surface interactions |
| 0.0 | 1.1 | PID_MET_PATHWAY | Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 5.1 | REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 0.0 | 2.9 | REACTOME_NETRIN1_SIGNALING | Genes involved in Netrin-1 signaling |
| 0.0 | 0.9 | REACTOME_ACTIVATION_OF_GENES_BY_ATF4 | Genes involved in Activation of Genes by ATF4 |
| 0.0 | 2.5 | REACTOME_MITOTIC_PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.0 | 0.9 | REACTOME_RECYCLING_PATHWAY_OF_L1 | Genes involved in Recycling pathway of L1 |
| 0.0 | 0.2 | REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN | Genes involved in Platelet Adhesion to exposed collagen |
| 0.0 | 0.2 | REACTOME_P38MAPK_EVENTS | Genes involved in p38MAPK events |
| 0.0 | 0.3 | REACTOME_CHOLESTEROL_BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
