Motif ID: Runx2_Bcl11a
Z-value: 1.605
Transcription factors associated with Runx2_Bcl11a:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Bcl11a | ENSMUSG00000000861.9 | Bcl11a |
| Runx2 | ENSMUSG00000039153.10 | Runx2 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Bcl11a | mm10_v2_chr11_+_24078173_24078219 | -0.41 | 1.9e-04 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.7 | 14.0 | GO:0046110 | xanthine metabolic process(GO:0046110) |
| 4.0 | 12.0 | GO:1903279 | regulation of calcium:sodium antiporter activity(GO:1903279) |
| 3.9 | 19.5 | GO:0034162 | toll-like receptor 9 signaling pathway(GO:0034162) |
| 3.5 | 10.5 | GO:0014738 | regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900) |
| 3.4 | 10.3 | GO:0050703 | interleukin-1 alpha secretion(GO:0050703) |
| 3.4 | 10.2 | GO:0072378 | blood coagulation, fibrin clot formation(GO:0072378) |
| 3.0 | 33.0 | GO:0042572 | retinol metabolic process(GO:0042572) |
| 2.9 | 26.5 | GO:0043615 | astrocyte cell migration(GO:0043615) |
| 2.9 | 8.6 | GO:0038095 | positive regulation of mast cell cytokine production(GO:0032765) Fc-epsilon receptor signaling pathway(GO:0038095) |
| 2.7 | 16.4 | GO:0006957 | complement activation, alternative pathway(GO:0006957) |
| 2.5 | 7.6 | GO:2000170 | positive regulation of peptidyl-cysteine S-nitrosylation(GO:2000170) |
| 2.5 | 12.3 | GO:0019852 | L-ascorbic acid metabolic process(GO:0019852) |
| 2.4 | 17.1 | GO:0045650 | negative regulation of macrophage differentiation(GO:0045650) |
| 2.4 | 7.2 | GO:0036292 | positive regulation of prostaglandin biosynthetic process(GO:0031394) DNA rewinding(GO:0036292) neutrophil clearance(GO:0097350) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280) |
| 2.3 | 7.0 | GO:1904020 | regulation of G-protein coupled receptor internalization(GO:1904020) |
| 2.2 | 11.0 | GO:0045347 | negative regulation of MHC class II biosynthetic process(GO:0045347) negative regulation of cytolysis(GO:0045918) |
| 2.2 | 6.6 | GO:0033364 | mast cell secretory granule organization(GO:0033364) |
| 2.2 | 6.5 | GO:2000642 | negative regulation of early endosome to late endosome transport(GO:2000642) |
| 2.1 | 6.4 | GO:0021837 | motogenic signaling involved in postnatal olfactory bulb interneuron migration(GO:0021837) positive regulation of mitotic cell cycle DNA replication(GO:1903465) |
| 2.0 | 6.0 | GO:2000297 | negative regulation of synapse maturation(GO:2000297) |
| 1.9 | 13.0 | GO:0038028 | insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) |
| 1.8 | 10.8 | GO:0097646 | calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647) |
| 1.8 | 12.5 | GO:0019532 | oxalate transport(GO:0019532) |
| 1.7 | 5.1 | GO:0038145 | macrophage colony-stimulating factor signaling pathway(GO:0038145) |
| 1.6 | 4.9 | GO:2000016 | negative regulation of determination of dorsal identity(GO:2000016) |
| 1.6 | 11.4 | GO:0043553 | negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) |
| 1.5 | 7.7 | GO:0060414 | aorta smooth muscle tissue morphogenesis(GO:0060414) |
| 1.5 | 3.0 | GO:2000501 | natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501) |
| 1.5 | 4.5 | GO:0051342 | regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344) |
| 1.5 | 4.5 | GO:0010752 | signal complex assembly(GO:0007172) regulation of cGMP-mediated signaling(GO:0010752) |
| 1.5 | 4.5 | GO:0050975 | sensory perception of touch(GO:0050975) |
| 1.5 | 4.4 | GO:0015920 | lipopolysaccharide transport(GO:0015920) |
| 1.3 | 4.0 | GO:0048687 | positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) |
| 1.3 | 2.6 | GO:0007621 | negative regulation of female receptivity(GO:0007621) |
| 1.3 | 5.1 | GO:0035937 | androgen catabolic process(GO:0006710) estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864) |
| 1.3 | 5.1 | GO:0021564 | glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564) |
| 1.2 | 14.2 | GO:0032000 | positive regulation of fatty acid beta-oxidation(GO:0032000) |
| 1.2 | 8.2 | GO:0015862 | uridine transport(GO:0015862) |
| 1.1 | 8.0 | GO:0070494 | regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495) |
| 1.1 | 4.4 | GO:0032910 | transforming growth factor beta3 production(GO:0032907) regulation of transforming growth factor beta3 production(GO:0032910) |
| 1.1 | 5.5 | GO:0043314 | negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313) |
| 1.1 | 4.3 | GO:0001550 | ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) |
| 1.1 | 7.5 | GO:0061718 | NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718) |
| 1.0 | 4.2 | GO:1900533 | medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535) |
| 1.0 | 3.0 | GO:0032829 | regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) |
| 1.0 | 6.0 | GO:0033600 | negative regulation of mammary gland epithelial cell proliferation(GO:0033600) regulation of branching involved in mammary gland duct morphogenesis(GO:0060762) |
| 1.0 | 3.9 | GO:0010813 | neuropeptide catabolic process(GO:0010813) |
| 1.0 | 4.9 | GO:0051182 | coenzyme transport(GO:0051182) |
| 0.9 | 2.8 | GO:0017055 | negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055) |
| 0.9 | 5.7 | GO:0006452 | translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905) |
| 0.9 | 2.8 | GO:0030300 | regulation of intestinal cholesterol absorption(GO:0030300) |
| 0.9 | 6.5 | GO:0009449 | gamma-aminobutyric acid biosynthetic process(GO:0009449) |
| 0.9 | 4.4 | GO:2000255 | negative regulation of male germ cell proliferation(GO:2000255) |
| 0.9 | 4.3 | GO:2000427 | positive regulation of apoptotic cell clearance(GO:2000427) |
| 0.8 | 6.7 | GO:0098707 | positive regulation of oligodendrocyte progenitor proliferation(GO:0070447) ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707) |
| 0.8 | 4.2 | GO:0042636 | negative regulation of hair cycle(GO:0042636) negative regulation of hair follicle development(GO:0051799) positive regulation of ovulation(GO:0060279) |
| 0.8 | 6.1 | GO:1901387 | positive regulation of voltage-gated calcium channel activity(GO:1901387) |
| 0.7 | 6.0 | GO:0030388 | fructose 1,6-bisphosphate metabolic process(GO:0030388) |
| 0.7 | 2.2 | GO:0060217 | hemangioblast cell differentiation(GO:0060217) |
| 0.7 | 2.1 | GO:1905051 | regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053) |
| 0.7 | 4.9 | GO:0043569 | negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569) |
| 0.7 | 3.4 | GO:0015671 | oxygen transport(GO:0015671) |
| 0.7 | 1.4 | GO:0001803 | type III hypersensitivity(GO:0001802) regulation of type III hypersensitivity(GO:0001803) positive regulation of type III hypersensitivity(GO:0001805) |
| 0.7 | 3.4 | GO:0032687 | negative regulation of interferon-alpha production(GO:0032687) |
| 0.7 | 2.7 | GO:1904048 | negative regulation of synaptic vesicle recycling(GO:1903422) regulation of spontaneous neurotransmitter secretion(GO:1904048) |
| 0.7 | 3.4 | GO:0030951 | establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) |
| 0.7 | 2.0 | GO:0071638 | negative regulation of monocyte chemotactic protein-1 production(GO:0071638) |
| 0.7 | 3.3 | GO:0001705 | ectoderm formation(GO:0001705) |
| 0.6 | 2.5 | GO:0019355 | nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628) |
| 0.6 | 6.1 | GO:0015701 | bicarbonate transport(GO:0015701) |
| 0.6 | 2.4 | GO:0060431 | primary lung bud formation(GO:0060431) |
| 0.6 | 2.4 | GO:0070317 | negative regulation of G0 to G1 transition(GO:0070317) |
| 0.6 | 2.4 | GO:1904425 | negative regulation of GTP binding(GO:1904425) |
| 0.6 | 1.1 | GO:1904529 | regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616) |
| 0.6 | 1.7 | GO:0071929 | alpha-tubulin acetylation(GO:0071929) |
| 0.6 | 1.7 | GO:0014809 | regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809) |
| 0.5 | 2.7 | GO:1904721 | regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721) |
| 0.5 | 4.2 | GO:0071361 | cellular response to ethanol(GO:0071361) |
| 0.5 | 1.0 | GO:2000097 | regulation of smooth muscle cell-matrix adhesion(GO:2000097) |
| 0.5 | 6.3 | GO:1901841 | regulation of high voltage-gated calcium channel activity(GO:1901841) |
| 0.5 | 1.0 | GO:0090071 | negative regulation of ribosome biogenesis(GO:0090071) |
| 0.5 | 5.4 | GO:0051923 | sulfation(GO:0051923) |
| 0.5 | 3.5 | GO:0030579 | ubiquitin-dependent SMAD protein catabolic process(GO:0030579) |
| 0.5 | 1.5 | GO:0035622 | intrahepatic bile duct development(GO:0035622) cholangiocyte proliferation(GO:1990705) |
| 0.5 | 4.9 | GO:0000042 | protein targeting to Golgi(GO:0000042) |
| 0.5 | 1.9 | GO:0010693 | negative regulation of alkaline phosphatase activity(GO:0010693) |
| 0.5 | 1.9 | GO:0051725 | protein de-ADP-ribosylation(GO:0051725) |
| 0.5 | 1.0 | GO:0021759 | globus pallidus development(GO:0021759) |
| 0.5 | 3.3 | GO:0010968 | regulation of microtubule nucleation(GO:0010968) |
| 0.5 | 0.9 | GO:0006703 | estrogen biosynthetic process(GO:0006703) |
| 0.4 | 1.3 | GO:0016554 | cytidine to uridine editing(GO:0016554) |
| 0.4 | 2.6 | GO:2000258 | negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258) |
| 0.4 | 3.8 | GO:0021894 | cerebral cortex GABAergic interneuron development(GO:0021894) |
| 0.4 | 2.1 | GO:0043985 | histone H4-R3 methylation(GO:0043985) |
| 0.4 | 1.2 | GO:0006550 | isoleucine catabolic process(GO:0006550) |
| 0.4 | 1.6 | GO:0061526 | regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579) acetylcholine secretion, neurotransmission(GO:0014055) regulation of acetylcholine secretion, neurotransmission(GO:0014056) positive regulation of synaptic transmission, cholinergic(GO:0032224) acetylcholine secretion(GO:0061526) |
| 0.4 | 1.6 | GO:0090472 | dibasic protein processing(GO:0090472) |
| 0.4 | 2.4 | GO:0044375 | regulation of peroxisome size(GO:0044375) |
| 0.4 | 2.3 | GO:0055064 | chloride ion homeostasis(GO:0055064) |
| 0.4 | 1.1 | GO:0036092 | phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092) |
| 0.4 | 2.6 | GO:0097428 | protein maturation by iron-sulfur cluster transfer(GO:0097428) |
| 0.4 | 1.8 | GO:0014053 | negative regulation of gamma-aminobutyric acid secretion(GO:0014053) |
| 0.4 | 1.5 | GO:0045903 | positive regulation of translational fidelity(GO:0045903) |
| 0.4 | 16.2 | GO:0045744 | negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744) |
| 0.4 | 1.4 | GO:0007412 | axon target recognition(GO:0007412) |
| 0.4 | 1.1 | GO:0032497 | detection of lipopolysaccharide(GO:0032497) |
| 0.4 | 1.4 | GO:0001867 | complement activation, lectin pathway(GO:0001867) |
| 0.4 | 6.0 | GO:0010669 | epithelial structure maintenance(GO:0010669) |
| 0.3 | 2.4 | GO:0006561 | proline biosynthetic process(GO:0006561) |
| 0.3 | 0.7 | GO:0010726 | positive regulation of hydrogen peroxide metabolic process(GO:0010726) |
| 0.3 | 1.4 | GO:0019509 | L-methionine biosynthetic process from methylthioadenosine(GO:0019509) |
| 0.3 | 2.0 | GO:0002606 | dendritic cell antigen processing and presentation(GO:0002468) regulation of dendritic cell antigen processing and presentation(GO:0002604) positive regulation of dendritic cell antigen processing and presentation(GO:0002606) |
| 0.3 | 1.3 | GO:0071157 | negative regulation of cell cycle arrest(GO:0071157) |
| 0.3 | 1.0 | GO:0035526 | retrograde transport, plasma membrane to Golgi(GO:0035526) |
| 0.3 | 3.8 | GO:0043011 | myeloid dendritic cell differentiation(GO:0043011) |
| 0.3 | 2.2 | GO:0034316 | negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316) |
| 0.3 | 1.5 | GO:0019659 | fermentation(GO:0006113) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661) |
| 0.3 | 2.4 | GO:0061042 | vascular wound healing(GO:0061042) |
| 0.3 | 1.5 | GO:0034638 | phosphatidylcholine catabolic process(GO:0034638) |
| 0.3 | 2.7 | GO:0048619 | embryonic hindgut morphogenesis(GO:0048619) |
| 0.3 | 2.4 | GO:0019388 | galactose catabolic process(GO:0019388) |
| 0.3 | 1.2 | GO:0071475 | cellular hyperosmotic salinity response(GO:0071475) |
| 0.3 | 2.0 | GO:0006627 | protein processing involved in protein targeting to mitochondrion(GO:0006627) |
| 0.3 | 6.4 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
| 0.3 | 1.6 | GO:1990928 | response to amino acid starvation(GO:1990928) |
| 0.3 | 17.9 | GO:0038083 | peptidyl-tyrosine autophosphorylation(GO:0038083) |
| 0.3 | 0.8 | GO:1900020 | regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020) |
| 0.3 | 1.6 | GO:0051503 | adenine nucleotide transport(GO:0051503) |
| 0.3 | 2.6 | GO:0031665 | negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665) |
| 0.3 | 2.0 | GO:0033564 | anterior/posterior axon guidance(GO:0033564) |
| 0.3 | 2.0 | GO:0036376 | sodium ion export from cell(GO:0036376) |
| 0.2 | 2.2 | GO:0035887 | aortic smooth muscle cell differentiation(GO:0035887) |
| 0.2 | 1.0 | GO:0014819 | regulation of skeletal muscle contraction(GO:0014819) |
| 0.2 | 2.6 | GO:0002347 | response to tumor cell(GO:0002347) |
| 0.2 | 1.0 | GO:0060398 | regulation of growth hormone receptor signaling pathway(GO:0060398) |
| 0.2 | 1.9 | GO:0045541 | negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206) |
| 0.2 | 0.7 | GO:0035964 | COPI-coated vesicle budding(GO:0035964) |
| 0.2 | 5.3 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
| 0.2 | 2.1 | GO:0070236 | negative regulation of activation-induced cell death of T cells(GO:0070236) |
| 0.2 | 14.8 | GO:0003073 | regulation of systemic arterial blood pressure(GO:0003073) |
| 0.2 | 0.9 | GO:0060838 | lymphatic endothelial cell fate commitment(GO:0060838) |
| 0.2 | 0.7 | GO:0060672 | epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672) |
| 0.2 | 1.8 | GO:0071372 | cellular response to follicle-stimulating hormone stimulus(GO:0071372) |
| 0.2 | 3.0 | GO:0030213 | hyaluronan biosynthetic process(GO:0030213) |
| 0.2 | 1.5 | GO:0031508 | pericentric heterochromatin assembly(GO:0031508) |
| 0.2 | 2.5 | GO:0000244 | spliceosomal tri-snRNP complex assembly(GO:0000244) |
| 0.2 | 2.3 | GO:0034551 | respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033) |
| 0.2 | 1.7 | GO:0071670 | smooth muscle cell chemotaxis(GO:0071670) |
| 0.2 | 2.3 | GO:2000766 | negative regulation of cytoplasmic translation(GO:2000766) |
| 0.2 | 1.0 | GO:0045039 | protein import into mitochondrial inner membrane(GO:0045039) |
| 0.2 | 6.0 | GO:0030325 | adrenal gland development(GO:0030325) |
| 0.2 | 1.2 | GO:0035360 | positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360) |
| 0.2 | 0.8 | GO:0002579 | positive regulation of antigen processing and presentation(GO:0002579) |
| 0.2 | 0.6 | GO:0019046 | release from viral latency(GO:0019046) |
| 0.2 | 1.4 | GO:0098909 | establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909) |
| 0.2 | 5.0 | GO:0015991 | ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662) |
| 0.2 | 3.3 | GO:0046597 | negative regulation of viral entry into host cell(GO:0046597) |
| 0.2 | 2.9 | GO:2000251 | positive regulation of actin cytoskeleton reorganization(GO:2000251) |
| 0.2 | 0.8 | GO:0031017 | exocrine pancreas development(GO:0031017) |
| 0.2 | 0.6 | GO:0046340 | diacylglycerol catabolic process(GO:0046340) |
| 0.2 | 1.0 | GO:0070070 | proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072) |
| 0.2 | 1.7 | GO:0061470 | interleukin-21 production(GO:0032625) T follicular helper cell differentiation(GO:0061470) interleukin-21 secretion(GO:0072619) |
| 0.2 | 1.9 | GO:2000653 | regulation of genetic imprinting(GO:2000653) |
| 0.2 | 0.5 | GO:1902396 | protein localization to bicellular tight junction(GO:1902396) |
| 0.2 | 3.9 | GO:0010574 | regulation of vascular endothelial growth factor production(GO:0010574) |
| 0.2 | 2.7 | GO:0042178 | xenobiotic catabolic process(GO:0042178) |
| 0.2 | 2.6 | GO:0006767 | water-soluble vitamin metabolic process(GO:0006767) |
| 0.2 | 1.0 | GO:0032957 | inositol trisphosphate metabolic process(GO:0032957) |
| 0.2 | 0.9 | GO:0016255 | attachment of GPI anchor to protein(GO:0016255) |
| 0.2 | 0.5 | GO:1901856 | negative regulation of cellular respiration(GO:1901856) |
| 0.2 | 0.8 | GO:0072675 | osteoclast fusion(GO:0072675) |
| 0.2 | 0.5 | GO:0001757 | somite specification(GO:0001757) |
| 0.1 | 0.4 | GO:0090202 | transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579) |
| 0.1 | 0.4 | GO:0071707 | immunoglobulin heavy chain V-D-J recombination(GO:0071707) |
| 0.1 | 0.7 | GO:0051012 | microtubule sliding(GO:0051012) negative regulation of nonmotile primary cilium assembly(GO:1902856) |
| 0.1 | 0.4 | GO:0006419 | alanyl-tRNA aminoacylation(GO:0006419) |
| 0.1 | 2.9 | GO:0032967 | positive regulation of collagen biosynthetic process(GO:0032967) |
| 0.1 | 1.1 | GO:0070886 | positive regulation of calcineurin-NFAT signaling cascade(GO:0070886) |
| 0.1 | 1.4 | GO:0030212 | hyaluronan metabolic process(GO:0030212) |
| 0.1 | 1.1 | GO:0060732 | positive regulation of inositol phosphate biosynthetic process(GO:0060732) |
| 0.1 | 0.5 | GO:0006121 | mitochondrial electron transport, succinate to ubiquinone(GO:0006121) |
| 0.1 | 0.6 | GO:1901097 | negative regulation of autophagosome maturation(GO:1901097) |
| 0.1 | 0.9 | GO:0007296 | vitellogenesis(GO:0007296) |
| 0.1 | 1.0 | GO:0021612 | facial nerve structural organization(GO:0021612) |
| 0.1 | 0.8 | GO:0070234 | positive regulation of T cell apoptotic process(GO:0070234) |
| 0.1 | 2.5 | GO:0001921 | positive regulation of receptor recycling(GO:0001921) |
| 0.1 | 7.8 | GO:0050810 | regulation of steroid biosynthetic process(GO:0050810) |
| 0.1 | 1.0 | GO:0032020 | ISG15-protein conjugation(GO:0032020) |
| 0.1 | 0.9 | GO:0006729 | tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146) |
| 0.1 | 0.5 | GO:0046654 | tetrahydrofolate biosynthetic process(GO:0046654) |
| 0.1 | 0.7 | GO:0006616 | SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616) |
| 0.1 | 4.9 | GO:0006890 | retrograde vesicle-mediated transport, Golgi to ER(GO:0006890) |
| 0.1 | 0.8 | GO:0090234 | regulation of centromere complex assembly(GO:0090230) regulation of kinetochore assembly(GO:0090234) |
| 0.1 | 1.9 | GO:0019835 | cytolysis(GO:0019835) |
| 0.1 | 1.2 | GO:0006465 | signal peptide processing(GO:0006465) |
| 0.1 | 0.9 | GO:0032049 | cardiolipin biosynthetic process(GO:0032049) |
| 0.1 | 0.6 | GO:0007256 | activation of JNKK activity(GO:0007256) |
| 0.1 | 4.5 | GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184) |
| 0.1 | 1.2 | GO:0044406 | adhesion of symbiont to host(GO:0044406) |
| 0.1 | 0.4 | GO:0015705 | iodide transport(GO:0015705) |
| 0.1 | 1.1 | GO:0060394 | negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394) |
| 0.1 | 0.9 | GO:0035372 | protein localization to microtubule(GO:0035372) |
| 0.1 | 4.2 | GO:0097031 | NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031) |
| 0.1 | 0.4 | GO:0052490 | suppression by virus of host apoptotic process(GO:0019050) negative regulation by symbiont of host apoptotic process(GO:0033668) modulation by virus of host apoptotic process(GO:0039526) response to cycloheximide(GO:0046898) negative regulation by symbiont of host programmed cell death(GO:0052041) negative regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052490) |
| 0.1 | 0.3 | GO:1990046 | positive regulation of mitochondrial DNA replication(GO:0090297) regulation of cardiolipin metabolic process(GO:1900208) positive regulation of cardiolipin metabolic process(GO:1900210) positive regulation of mitochondrial DNA metabolic process(GO:1901860) stress-induced mitochondrial fusion(GO:1990046) |
| 0.1 | 0.5 | GO:0006384 | transcription initiation from RNA polymerase III promoter(GO:0006384) |
| 0.1 | 0.4 | GO:0006447 | regulation of translational initiation by iron(GO:0006447) positive regulation of translational initiation by iron(GO:0045994) |
| 0.1 | 0.8 | GO:0036506 | maintenance of unfolded protein(GO:0036506) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378) |
| 0.1 | 0.6 | GO:0035948 | positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072366) |
| 0.1 | 1.0 | GO:0043144 | snoRNA processing(GO:0043144) |
| 0.1 | 0.6 | GO:0035331 | negative regulation of hippo signaling(GO:0035331) |
| 0.1 | 0.4 | GO:0015744 | succinate transport(GO:0015744) |
| 0.1 | 1.1 | GO:0061469 | regulation of type B pancreatic cell proliferation(GO:0061469) |
| 0.1 | 0.3 | GO:0009165 | nucleotide biosynthetic process(GO:0009165) |
| 0.1 | 0.4 | GO:0006421 | asparaginyl-tRNA aminoacylation(GO:0006421) |
| 0.1 | 1.0 | GO:0007190 | activation of adenylate cyclase activity(GO:0007190) |
| 0.1 | 3.6 | GO:0071277 | cellular response to calcium ion(GO:0071277) |
| 0.1 | 0.8 | GO:0071549 | cellular response to dexamethasone stimulus(GO:0071549) |
| 0.1 | 6.8 | GO:0030032 | lamellipodium assembly(GO:0030032) |
| 0.1 | 0.7 | GO:0046415 | urate metabolic process(GO:0046415) |
| 0.1 | 2.6 | GO:1900026 | positive regulation of substrate adhesion-dependent cell spreading(GO:1900026) |
| 0.1 | 0.7 | GO:0018026 | peptidyl-lysine monomethylation(GO:0018026) |
| 0.1 | 0.5 | GO:0006122 | mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122) |
| 0.1 | 0.9 | GO:1902170 | cellular response to reactive nitrogen species(GO:1902170) |
| 0.1 | 0.7 | GO:0032510 | endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510) |
| 0.1 | 1.3 | GO:0045056 | transcytosis(GO:0045056) |
| 0.1 | 1.1 | GO:0006359 | regulation of transcription from RNA polymerase III promoter(GO:0006359) |
| 0.1 | 0.6 | GO:0070475 | rRNA base methylation(GO:0070475) |
| 0.1 | 0.5 | GO:1903894 | regulation of IRE1-mediated unfolded protein response(GO:1903894) |
| 0.1 | 0.2 | GO:0035672 | phospholipid efflux(GO:0033700) oligopeptide transmembrane transport(GO:0035672) drug export(GO:0046618) |
| 0.1 | 0.3 | GO:0015825 | L-serine transport(GO:0015825) |
| 0.1 | 0.7 | GO:1903025 | regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025) |
| 0.1 | 1.2 | GO:0090201 | negative regulation of release of cytochrome c from mitochondria(GO:0090201) |
| 0.1 | 0.2 | GO:0043379 | rRNA export from nucleus(GO:0006407) memory T cell differentiation(GO:0043379) |
| 0.1 | 0.3 | GO:0060055 | angiogenesis involved in wound healing(GO:0060055) |
| 0.1 | 0.5 | GO:0033689 | negative regulation of osteoblast proliferation(GO:0033689) |
| 0.1 | 2.6 | GO:0071346 | cellular response to interferon-gamma(GO:0071346) |
| 0.1 | 2.4 | GO:0010862 | positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862) |
| 0.1 | 0.6 | GO:0044130 | negative regulation of growth of symbiont in host(GO:0044130) negative regulation of growth of symbiont involved in interaction with host(GO:0044146) |
| 0.1 | 0.7 | GO:0035428 | hexose transmembrane transport(GO:0035428) |
| 0.1 | 1.4 | GO:0045776 | negative regulation of blood pressure(GO:0045776) |
| 0.1 | 2.7 | GO:0045670 | regulation of osteoclast differentiation(GO:0045670) |
| 0.1 | 0.5 | GO:0036265 | RNA (guanine-N7)-methylation(GO:0036265) |
| 0.1 | 1.1 | GO:0030150 | protein import into mitochondrial matrix(GO:0030150) |
| 0.1 | 0.6 | GO:1903301 | fructose 2,6-bisphosphate metabolic process(GO:0006003) positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301) |
| 0.1 | 1.5 | GO:0051926 | negative regulation of calcium ion transport(GO:0051926) |
| 0.1 | 0.2 | GO:0035330 | regulation of hippo signaling(GO:0035330) |
| 0.1 | 0.6 | GO:1903800 | positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800) |
| 0.1 | 0.3 | GO:0006363 | termination of RNA polymerase I transcription(GO:0006363) |
| 0.1 | 0.6 | GO:0042989 | sequestering of actin monomers(GO:0042989) |
| 0.1 | 1.2 | GO:0006744 | ubiquinone biosynthetic process(GO:0006744) |
| 0.1 | 0.8 | GO:0003215 | cardiac right ventricle morphogenesis(GO:0003215) |
| 0.1 | 1.0 | GO:0033006 | regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304) |
| 0.1 | 2.3 | GO:0001541 | ovarian follicle development(GO:0001541) |
| 0.1 | 1.1 | GO:0006047 | UDP-N-acetylglucosamine metabolic process(GO:0006047) |
| 0.1 | 2.2 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
| 0.1 | 9.3 | GO:0007416 | synapse assembly(GO:0007416) |
| 0.1 | 1.0 | GO:0046069 | cGMP catabolic process(GO:0046069) |
| 0.1 | 0.5 | GO:0033152 | immunoglobulin V(D)J recombination(GO:0033152) |
| 0.1 | 1.2 | GO:0097178 | ruffle assembly(GO:0097178) |
| 0.1 | 0.7 | GO:0043508 | negative regulation of JUN kinase activity(GO:0043508) |
| 0.1 | 1.4 | GO:0002089 | lens morphogenesis in camera-type eye(GO:0002089) |
| 0.1 | 1.2 | GO:0006891 | intra-Golgi vesicle-mediated transport(GO:0006891) |
| 0.1 | 1.0 | GO:0071625 | vocalization behavior(GO:0071625) |
| 0.1 | 0.8 | GO:0032464 | positive regulation of protein homooligomerization(GO:0032464) |
| 0.0 | 0.3 | GO:0061092 | involuntary skeletal muscle contraction(GO:0003011) detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962) regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092) |
| 0.0 | 0.8 | GO:0002115 | store-operated calcium entry(GO:0002115) |
| 0.0 | 0.9 | GO:0034389 | lipid particle organization(GO:0034389) |
| 0.0 | 0.3 | GO:0071630 | nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630) |
| 0.0 | 1.3 | GO:0018345 | protein palmitoylation(GO:0018345) |
| 0.0 | 2.4 | GO:0002181 | cytoplasmic translation(GO:0002181) |
| 0.0 | 0.7 | GO:0048268 | clathrin coat assembly(GO:0048268) |
| 0.0 | 0.3 | GO:0017196 | N-terminal peptidyl-methionine acetylation(GO:0017196) |
| 0.0 | 0.8 | GO:0010614 | negative regulation of cardiac muscle hypertrophy(GO:0010614) |
| 0.0 | 0.9 | GO:0031648 | protein destabilization(GO:0031648) |
| 0.0 | 0.7 | GO:0097435 | fibril organization(GO:0097435) |
| 0.0 | 1.3 | GO:0050830 | defense response to Gram-positive bacterium(GO:0050830) |
| 0.0 | 0.3 | GO:0007016 | cytoskeletal anchoring at plasma membrane(GO:0007016) |
| 0.0 | 0.6 | GO:1904872 | regulation of telomerase RNA localization to Cajal body(GO:1904872) positive regulation of telomerase RNA localization to Cajal body(GO:1904874) |
| 0.0 | 1.3 | GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146) |
| 0.0 | 0.4 | GO:0048642 | negative regulation of skeletal muscle tissue development(GO:0048642) |
| 0.0 | 0.5 | GO:0051044 | positive regulation of membrane protein ectodomain proteolysis(GO:0051044) |
| 0.0 | 1.1 | GO:0010972 | negative regulation of G2/M transition of mitotic cell cycle(GO:0010972) |
| 0.0 | 0.4 | GO:0006383 | transcription from RNA polymerase III promoter(GO:0006383) |
| 0.0 | 0.2 | GO:2000096 | positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096) |
| 0.0 | 0.1 | GO:0098501 | polynucleotide dephosphorylation(GO:0098501) |
| 0.0 | 1.5 | GO:0010811 | positive regulation of cell-substrate adhesion(GO:0010811) |
| 0.0 | 0.9 | GO:2000785 | regulation of autophagosome assembly(GO:2000785) |
| 0.0 | 0.3 | GO:0051085 | chaperone mediated protein folding requiring cofactor(GO:0051085) |
| 0.0 | 0.4 | GO:0046498 | S-adenosylhomocysteine metabolic process(GO:0046498) |
| 0.0 | 0.6 | GO:0043171 | peptide catabolic process(GO:0043171) |
| 0.0 | 0.8 | GO:0015844 | monoamine transport(GO:0015844) |
| 0.0 | 0.1 | GO:0000973 | posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973) |
| 0.0 | 0.5 | GO:0031935 | regulation of chromatin silencing(GO:0031935) |
| 0.0 | 0.4 | GO:0000387 | spliceosomal snRNP assembly(GO:0000387) |
| 0.0 | 0.1 | GO:1902775 | mitochondrial large ribosomal subunit assembly(GO:1902775) |
| 0.0 | 0.1 | GO:0097084 | vascular smooth muscle cell development(GO:0097084) |
| 0.0 | 0.9 | GO:0006818 | hydrogen transport(GO:0006818) |
| 0.0 | 2.0 | GO:0051607 | defense response to virus(GO:0051607) |
| 0.0 | 0.0 | GO:0032782 | bile acid secretion(GO:0032782) |
| 0.0 | 0.2 | GO:0045947 | negative regulation of translational initiation(GO:0045947) |
| 0.0 | 0.1 | GO:1901223 | negative regulation of NIK/NF-kappaB signaling(GO:1901223) |
| 0.0 | 0.2 | GO:0014067 | negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067) |
| 0.0 | 0.8 | GO:0021766 | hippocampus development(GO:0021766) |
| 0.0 | 0.4 | GO:0045214 | sarcomere organization(GO:0045214) |
| 0.0 | 0.4 | GO:0070536 | protein K63-linked deubiquitination(GO:0070536) |
| 0.0 | 0.3 | GO:0009268 | response to pH(GO:0009268) |
| 0.0 | 0.2 | GO:2000369 | regulation of clathrin-mediated endocytosis(GO:2000369) |
| 0.0 | 0.1 | GO:1902176 | negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902176) |
| 0.0 | 0.1 | GO:0015819 | lysine transport(GO:0015819) ornithine transport(GO:0015822) |
| 0.0 | 0.0 | GO:0018171 | peptidyl-cysteine oxidation(GO:0018171) |
| 0.0 | 0.1 | GO:0070571 | negative regulation of neuron projection regeneration(GO:0070571) |
| 0.0 | 0.1 | GO:0001682 | tRNA 5'-leader removal(GO:0001682) |
| 0.0 | 0.8 | GO:0008088 | axo-dendritic transport(GO:0008088) |
| 0.0 | 0.4 | GO:0072583 | clathrin-mediated endocytosis(GO:0072583) |
| 0.0 | 0.1 | GO:0050909 | sensory perception of taste(GO:0050909) |
| 0.0 | 0.0 | GO:0072344 | rescue of stalled ribosome(GO:0072344) |
| 0.0 | 0.1 | GO:0015937 | coenzyme A biosynthetic process(GO:0015937) |
| 0.0 | 0.2 | GO:1902653 | cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 11.7 | 46.8 | GO:0031838 | haptoglobin-hemoglobin complex(GO:0031838) |
| 2.6 | 26.3 | GO:0032009 | early phagosome(GO:0032009) |
| 2.2 | 10.8 | GO:1903440 | calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440) |
| 2.0 | 14.0 | GO:0005890 | sodium:potassium-exchanging ATPase complex(GO:0005890) |
| 1.7 | 13.8 | GO:0042629 | mast cell granule(GO:0042629) |
| 1.7 | 5.1 | GO:1990682 | CSF1-CSF1R complex(GO:1990682) |
| 1.4 | 4.2 | GO:0043512 | inhibin A complex(GO:0043512) |
| 1.3 | 6.5 | GO:0038039 | G-protein coupled receptor heterodimeric complex(GO:0038039) |
| 1.3 | 15.6 | GO:0020005 | symbiont-containing vacuole membrane(GO:0020005) |
| 1.2 | 4.9 | GO:0042567 | insulin-like growth factor ternary complex(GO:0042567) |
| 1.1 | 3.4 | GO:0044299 | C-fiber(GO:0044299) |
| 1.0 | 9.2 | GO:0031254 | uropod(GO:0001931) cell trailing edge(GO:0031254) |
| 1.0 | 2.9 | GO:0038045 | large latent transforming growth factor-beta complex(GO:0038045) |
| 0.9 | 4.5 | GO:0034751 | aryl hydrocarbon receptor complex(GO:0034751) |
| 0.8 | 6.7 | GO:0097433 | dense body(GO:0097433) |
| 0.7 | 2.2 | GO:0033193 | Lsd1/2 complex(GO:0033193) |
| 0.7 | 1.5 | GO:0005868 | cytoplasmic dynein complex(GO:0005868) |
| 0.6 | 1.7 | GO:0045098 | type III intermediate filament(GO:0045098) |
| 0.5 | 5.7 | GO:0005642 | annulate lamellae(GO:0005642) |
| 0.5 | 8.6 | GO:0017146 | NMDA selective glutamate receptor complex(GO:0017146) |
| 0.5 | 3.5 | GO:0000220 | vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220) |
| 0.5 | 1.5 | GO:0051233 | spindle midzone(GO:0051233) |
| 0.5 | 42.4 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.5 | 3.4 | GO:0005638 | lamin filament(GO:0005638) |
| 0.4 | 4.8 | GO:0016471 | vacuolar proton-transporting V-type ATPase complex(GO:0016471) |
| 0.4 | 8.1 | GO:0097225 | sperm midpiece(GO:0097225) |
| 0.4 | 3.8 | GO:0097208 | alveolar lamellar body(GO:0097208) |
| 0.4 | 1.7 | GO:0014802 | terminal cisterna(GO:0014802) |
| 0.4 | 1.7 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.4 | 10.1 | GO:0030137 | COPI-coated vesicle(GO:0030137) |
| 0.4 | 6.3 | GO:0097228 | sperm principal piece(GO:0097228) |
| 0.4 | 1.1 | GO:0034272 | phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272) |
| 0.4 | 2.5 | GO:0030130 | clathrin coat of trans-Golgi network vesicle(GO:0030130) |
| 0.4 | 1.1 | GO:0034457 | Mpp10 complex(GO:0034457) |
| 0.3 | 4.5 | GO:0005614 | interstitial matrix(GO:0005614) |
| 0.3 | 1.6 | GO:0012510 | trans-Golgi network transport vesicle membrane(GO:0012510) |
| 0.3 | 3.1 | GO:0071439 | clathrin complex(GO:0071439) |
| 0.3 | 2.7 | GO:0048787 | presynaptic active zone membrane(GO:0048787) |
| 0.3 | 2.6 | GO:0042581 | specific granule(GO:0042581) |
| 0.3 | 2.9 | GO:0034709 | methylosome(GO:0034709) |
| 0.3 | 1.2 | GO:0043564 | Ku70:Ku80 complex(GO:0043564) |
| 0.3 | 1.4 | GO:0071144 | SMAD2-SMAD3 protein complex(GO:0071144) |
| 0.3 | 3.1 | GO:0042582 | primary lysosome(GO:0005766) azurophil granule(GO:0042582) |
| 0.3 | 0.3 | GO:0070820 | tertiary granule(GO:0070820) |
| 0.3 | 4.5 | GO:0031528 | microvillus membrane(GO:0031528) |
| 0.3 | 0.8 | GO:0042720 | mitochondrial inner membrane peptidase complex(GO:0042720) |
| 0.3 | 12.8 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.2 | 6.3 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
| 0.2 | 9.2 | GO:0048786 | presynaptic active zone(GO:0048786) |
| 0.2 | 1.0 | GO:0042583 | chromaffin granule(GO:0042583) |
| 0.2 | 1.0 | GO:0042719 | mitochondrial intermembrane space protein transporter complex(GO:0042719) |
| 0.2 | 2.4 | GO:0033270 | paranode region of axon(GO:0033270) juxtaparanode region of axon(GO:0044224) |
| 0.2 | 1.0 | GO:0097513 | myosin II filament(GO:0097513) |
| 0.2 | 0.6 | GO:0043540 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540) |
| 0.2 | 2.3 | GO:0098643 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
| 0.2 | 1.0 | GO:1990462 | omegasome(GO:1990462) |
| 0.2 | 4.3 | GO:0001891 | phagocytic cup(GO:0001891) |
| 0.2 | 0.9 | GO:1990604 | IRE1-TRAF2-ASK1 complex(GO:1990604) |
| 0.2 | 2.0 | GO:0000176 | nuclear exosome (RNase complex)(GO:0000176) |
| 0.2 | 0.2 | GO:1990812 | growth cone filopodium(GO:1990812) |
| 0.2 | 2.9 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
| 0.2 | 0.5 | GO:0046581 | intercellular canaliculus(GO:0046581) |
| 0.2 | 0.9 | GO:0042765 | GPI-anchor transamidase complex(GO:0042765) |
| 0.2 | 4.3 | GO:0031430 | M band(GO:0031430) |
| 0.1 | 1.2 | GO:0005787 | signal peptidase complex(GO:0005787) |
| 0.1 | 0.6 | GO:0090661 | box H/ACA telomerase RNP complex(GO:0090661) |
| 0.1 | 2.2 | GO:0016010 | dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665) |
| 0.1 | 13.0 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
| 0.1 | 31.8 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 0.1 | 0.9 | GO:0031467 | Cul7-RING ubiquitin ligase complex(GO:0031467) |
| 0.1 | 0.9 | GO:0042734 | presynaptic membrane(GO:0042734) |
| 0.1 | 1.4 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 0.1 | 0.4 | GO:0097512 | cardiac myofibril(GO:0097512) |
| 0.1 | 1.8 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
| 0.1 | 0.8 | GO:0071818 | BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379) |
| 0.1 | 2.2 | GO:0071564 | npBAF complex(GO:0071564) |
| 0.1 | 0.3 | GO:0001405 | presequence translocase-associated import motor(GO:0001405) |
| 0.1 | 1.8 | GO:0030008 | TRAPP complex(GO:0030008) |
| 0.1 | 2.4 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.1 | 1.0 | GO:0000243 | commitment complex(GO:0000243) |
| 0.1 | 0.8 | GO:0089701 | U2AF(GO:0089701) |
| 0.1 | 0.8 | GO:0042613 | MHC class II protein complex(GO:0042613) |
| 0.1 | 1.7 | GO:1902711 | GABA-A receptor complex(GO:1902711) |
| 0.1 | 1.8 | GO:0031229 | integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) |
| 0.1 | 1.2 | GO:0043240 | Fanconi anaemia nuclear complex(GO:0043240) |
| 0.1 | 2.3 | GO:0005666 | DNA-directed RNA polymerase III complex(GO:0005666) |
| 0.1 | 0.5 | GO:0043527 | tRNA methyltransferase complex(GO:0043527) |
| 0.1 | 0.3 | GO:0005916 | fascia adherens(GO:0005916) |
| 0.1 | 0.3 | GO:0033186 | CAF-1 complex(GO:0033186) |
| 0.1 | 3.3 | GO:0032391 | photoreceptor connecting cilium(GO:0032391) |
| 0.1 | 0.4 | GO:1990130 | Iml1 complex(GO:1990130) |
| 0.1 | 4.2 | GO:0045271 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
| 0.1 | 0.4 | GO:0005744 | mitochondrial inner membrane presequence translocase complex(GO:0005744) |
| 0.1 | 2.5 | GO:0031941 | filamentous actin(GO:0031941) |
| 0.1 | 0.1 | GO:0043293 | apoptosome(GO:0043293) |
| 0.1 | 19.5 | GO:0045177 | apical part of cell(GO:0045177) |
| 0.1 | 0.2 | GO:0071001 | U4/U6 snRNP(GO:0071001) |
| 0.1 | 0.6 | GO:0031143 | pseudopodium(GO:0031143) |
| 0.1 | 0.5 | GO:0005958 | DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807) |
| 0.1 | 1.4 | GO:0005847 | mRNA cleavage and polyadenylation specificity factor complex(GO:0005847) |
| 0.1 | 0.6 | GO:0061574 | ASAP complex(GO:0061574) |
| 0.1 | 0.3 | GO:0002189 | ribose phosphate diphosphokinase complex(GO:0002189) |
| 0.1 | 1.3 | GO:0005921 | gap junction(GO:0005921) |
| 0.1 | 1.4 | GO:0071339 | MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339) |
| 0.1 | 0.5 | GO:0000127 | transcription factor TFIIIC complex(GO:0000127) |
| 0.1 | 2.1 | GO:0000314 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
| 0.1 | 0.7 | GO:0031080 | nuclear pore outer ring(GO:0031080) |
| 0.1 | 0.4 | GO:0097255 | R2TP complex(GO:0097255) |
| 0.1 | 1.3 | GO:0044298 | neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298) |
| 0.1 | 0.7 | GO:0035686 | sperm fibrous sheath(GO:0035686) |
| 0.1 | 4.6 | GO:0005604 | basement membrane(GO:0005604) |
| 0.1 | 6.9 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.1 | 50.1 | GO:0005615 | extracellular space(GO:0005615) |
| 0.1 | 0.4 | GO:0005903 | brush border(GO:0005903) |
| 0.1 | 5.7 | GO:0016605 | PML body(GO:0016605) |
| 0.1 | 1.0 | GO:0035253 | ciliary rootlet(GO:0035253) |
| 0.1 | 0.4 | GO:0097165 | nuclear stress granule(GO:0097165) |
| 0.1 | 0.5 | GO:0042587 | glycogen granule(GO:0042587) |
| 0.1 | 1.4 | GO:0016328 | lateral plasma membrane(GO:0016328) |
| 0.1 | 3.9 | GO:0031975 | nuclear envelope(GO:0005635) envelope(GO:0031975) |
| 0.1 | 5.3 | GO:0043204 | perikaryon(GO:0043204) |
| 0.1 | 0.5 | GO:0016272 | prefoldin complex(GO:0016272) |
| 0.1 | 1.6 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.1 | 0.2 | GO:0033596 | TSC1-TSC2 complex(GO:0033596) |
| 0.1 | 0.5 | GO:0005750 | mitochondrial respiratory chain complex III(GO:0005750) |
| 0.0 | 11.9 | GO:0019898 | extrinsic component of membrane(GO:0019898) |
| 0.0 | 6.6 | GO:0043235 | receptor complex(GO:0043235) |
| 0.0 | 0.6 | GO:0098799 | outer mitochondrial membrane protein complex(GO:0098799) |
| 0.0 | 0.5 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
| 0.0 | 1.3 | GO:0035371 | microtubule plus-end(GO:0035371) |
| 0.0 | 0.4 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
| 0.0 | 2.1 | GO:0001669 | acrosomal vesicle(GO:0001669) |
| 0.0 | 0.4 | GO:0031011 | Ino80 complex(GO:0031011) |
| 0.0 | 2.3 | GO:0030496 | midbody(GO:0030496) |
| 0.0 | 1.0 | GO:0005684 | U2-type spliceosomal complex(GO:0005684) |
| 0.0 | 1.5 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
| 0.0 | 0.3 | GO:0005685 | U1 snRNP(GO:0005685) |
| 0.0 | 0.3 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
| 0.0 | 1.5 | GO:0005793 | endoplasmic reticulum-Golgi intermediate compartment(GO:0005793) |
| 0.0 | 5.5 | GO:0005769 | early endosome(GO:0005769) |
| 0.0 | 0.4 | GO:0005865 | striated muscle thin filament(GO:0005865) |
| 0.0 | 6.7 | GO:0005925 | focal adhesion(GO:0005925) |
| 0.0 | 0.4 | GO:0097440 | apical dendrite(GO:0097440) |
| 0.0 | 8.8 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
| 0.0 | 0.3 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.0 | 1.6 | GO:0030426 | growth cone(GO:0030426) |
| 0.0 | 1.1 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 0.0 | 0.5 | GO:0008180 | COP9 signalosome(GO:0008180) |
| 0.0 | 0.3 | GO:0031414 | N-terminal protein acetyltransferase complex(GO:0031414) |
| 0.0 | 0.3 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
| 0.0 | 0.1 | GO:0036126 | sperm flagellum(GO:0036126) |
| 0.0 | 0.1 | GO:0036157 | outer dynein arm(GO:0036157) |
| 0.0 | 0.7 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.0 | 0.1 | GO:0030677 | ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681) |
| 0.0 | 0.7 | GO:0005811 | lipid particle(GO:0005811) |
| 0.0 | 0.5 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
| 0.0 | 0.2 | GO:0031514 | motile cilium(GO:0031514) |
| 0.0 | 0.6 | GO:0005923 | bicellular tight junction(GO:0005923) occluding junction(GO:0070160) |
| 0.0 | 1.3 | GO:0005740 | mitochondrial envelope(GO:0005740) |
| 0.0 | 18.2 | GO:0070062 | extracellular exosome(GO:0070062) |
| 0.0 | 1.5 | GO:0031301 | integral component of organelle membrane(GO:0031301) |
| 0.0 | 0.1 | GO:0031595 | nuclear proteasome complex(GO:0031595) cytosolic proteasome complex(GO:0031597) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 11.7 | 46.8 | GO:0031721 | haptoglobin binding(GO:0031720) hemoglobin alpha binding(GO:0031721) |
| 4.7 | 32.9 | GO:0052650 | NADP-retinol dehydrogenase activity(GO:0052650) |
| 4.1 | 16.4 | GO:0001851 | complement component C3b binding(GO:0001851) |
| 4.1 | 12.2 | GO:0036313 | phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313) |
| 3.5 | 14.0 | GO:0030151 | molybdenum ion binding(GO:0030151) |
| 2.9 | 11.4 | GO:0031727 | CCR2 chemokine receptor binding(GO:0031727) |
| 2.8 | 8.5 | GO:0015038 | glutathione disulfide oxidoreductase activity(GO:0015038) |
| 2.6 | 10.2 | GO:0003810 | protein-glutamine gamma-glutamyltransferase activity(GO:0003810) |
| 2.2 | 11.0 | GO:0048248 | CXCR3 chemokine receptor binding(GO:0048248) |
| 2.2 | 10.8 | GO:0097643 | amylin receptor activity(GO:0097643) |
| 1.9 | 7.6 | GO:0070573 | tripeptidyl-peptidase activity(GO:0008240) metallodipeptidase activity(GO:0070573) |
| 1.8 | 5.4 | GO:0050656 | 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656) |
| 1.8 | 7.2 | GO:0004859 | phospholipase inhibitor activity(GO:0004859) phospholipase A2 inhibitor activity(GO:0019834) |
| 1.8 | 5.3 | GO:0004517 | nitric-oxide synthase activity(GO:0004517) |
| 1.7 | 6.6 | GO:0050786 | RAGE receptor binding(GO:0050786) |
| 1.6 | 6.5 | GO:0004111 | creatine kinase activity(GO:0004111) |
| 1.6 | 6.3 | GO:0005008 | hepatocyte growth factor-activated receptor activity(GO:0005008) |
| 1.5 | 4.5 | GO:0036004 | GAF domain binding(GO:0036004) |
| 1.5 | 1.5 | GO:0051429 | corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430) |
| 1.5 | 4.5 | GO:0001875 | lipopolysaccharide receptor activity(GO:0001875) |
| 1.4 | 14.0 | GO:0008556 | sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556) |
| 1.4 | 32.9 | GO:0048020 | CCR chemokine receptor binding(GO:0048020) |
| 1.2 | 6.1 | GO:0008865 | fructokinase activity(GO:0008865) mannokinase activity(GO:0019158) |
| 1.2 | 18.8 | GO:0035325 | Toll-like receptor binding(GO:0035325) |
| 1.1 | 3.4 | GO:0070890 | L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890) |
| 1.1 | 3.4 | GO:0005344 | oxygen transporter activity(GO:0005344) |
| 1.1 | 12.5 | GO:0019531 | secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531) |
| 1.1 | 4.4 | GO:0004667 | prostaglandin-D synthase activity(GO:0004667) |
| 1.1 | 6.5 | GO:0004965 | G-protein coupled GABA receptor activity(GO:0004965) |
| 1.0 | 17.9 | GO:0050811 | GABA receptor binding(GO:0050811) |
| 1.0 | 6.0 | GO:0004332 | fructose-bisphosphate aldolase activity(GO:0004332) |
| 1.0 | 3.9 | GO:0030984 | kininogen binding(GO:0030984) |
| 1.0 | 5.8 | GO:0004920 | interleukin-10 receptor activity(GO:0004920) |
| 1.0 | 6.7 | GO:0015091 | ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510) |
| 0.9 | 2.8 | GO:0002153 | steroid receptor RNA activator RNA binding(GO:0002153) |
| 0.9 | 6.5 | GO:0004351 | glutamate decarboxylase activity(GO:0004351) |
| 0.9 | 2.6 | GO:0031752 | D3 dopamine receptor binding(GO:0031750) D5 dopamine receptor binding(GO:0031752) |
| 0.9 | 1.7 | GO:0004105 | choline-phosphate cytidylyltransferase activity(GO:0004105) |
| 0.8 | 7.6 | GO:0030550 | acetylcholine receptor inhibitor activity(GO:0030550) |
| 0.8 | 18.3 | GO:0005520 | insulin-like growth factor binding(GO:0005520) |
| 0.8 | 4.9 | GO:0051185 | coenzyme transporter activity(GO:0051185) |
| 0.8 | 4.0 | GO:0005030 | neurotrophin receptor activity(GO:0005030) |
| 0.8 | 3.1 | GO:0001847 | opsonin receptor activity(GO:0001847) |
| 0.7 | 6.4 | GO:0005007 | fibroblast growth factor-activated receptor activity(GO:0005007) |
| 0.7 | 4.9 | GO:0098821 | BMP receptor activity(GO:0098821) |
| 0.7 | 4.2 | GO:0070699 | type II activin receptor binding(GO:0070699) |
| 0.7 | 6.0 | GO:0030274 | LIM domain binding(GO:0030274) |
| 0.7 | 2.0 | GO:1990050 | phosphatidic acid transporter activity(GO:1990050) |
| 0.6 | 4.5 | GO:0043423 | 3-phosphoinositide-dependent protein kinase binding(GO:0043423) |
| 0.6 | 3.1 | GO:0004563 | beta-N-acetylhexosaminidase activity(GO:0004563) |
| 0.6 | 2.5 | GO:0004515 | nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515) |
| 0.6 | 2.4 | GO:0097003 | adipokinetic hormone receptor activity(GO:0097003) |
| 0.6 | 2.4 | GO:0004735 | pyrroline-5-carboxylate reductase activity(GO:0004735) |
| 0.6 | 7.7 | GO:0010314 | phosphatidylinositol-5-phosphate binding(GO:0010314) |
| 0.6 | 2.4 | GO:0050436 | microfibril binding(GO:0050436) |
| 0.6 | 6.9 | GO:0008553 | hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553) |
| 0.5 | 4.3 | GO:0005025 | transforming growth factor beta receptor activity, type I(GO:0005025) |
| 0.5 | 2.1 | GO:0035243 | protein-arginine omega-N symmetric methyltransferase activity(GO:0035243) |
| 0.5 | 1.6 | GO:0046964 | 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964) |
| 0.5 | 7.0 | GO:0071855 | neuropeptide receptor binding(GO:0071855) |
| 0.5 | 0.5 | GO:0004637 | phosphoribosylamine-glycine ligase activity(GO:0004637) |
| 0.5 | 9.1 | GO:0005337 | nucleoside transmembrane transporter activity(GO:0005337) |
| 0.5 | 14.3 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
| 0.5 | 1.9 | GO:0004999 | vasoactive intestinal polypeptide receptor activity(GO:0004999) |
| 0.5 | 8.4 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) |
| 0.5 | 2.8 | GO:0016453 | acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453) |
| 0.5 | 4.6 | GO:0044548 | S100 protein binding(GO:0044548) |
| 0.5 | 2.7 | GO:0060698 | endoribonuclease inhibitor activity(GO:0060698) |
| 0.4 | 13.0 | GO:0043539 | insulin-like growth factor receptor binding(GO:0005159) protein serine/threonine kinase activator activity(GO:0043539) |
| 0.4 | 1.3 | GO:0004126 | cytidine deaminase activity(GO:0004126) |
| 0.4 | 1.7 | GO:0010484 | H3 histone acetyltransferase activity(GO:0010484) |
| 0.4 | 1.3 | GO:0008330 | protein tyrosine/threonine phosphatase activity(GO:0008330) |
| 0.4 | 1.2 | GO:0008534 | oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534) |
| 0.4 | 2.4 | GO:0035381 | extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381) |
| 0.4 | 6.2 | GO:0017070 | U6 snRNA binding(GO:0017070) |
| 0.4 | 5.6 | GO:0031210 | phosphatidylcholine binding(GO:0031210) |
| 0.4 | 4.4 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
| 0.4 | 13.6 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
| 0.4 | 1.8 | GO:0070404 | NADH binding(GO:0070404) |
| 0.4 | 1.1 | GO:0001032 | RNA polymerase III type 3 promoter DNA binding(GO:0001032) |
| 0.4 | 11.7 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
| 0.4 | 1.4 | GO:0031694 | alpha-2A adrenergic receptor binding(GO:0031694) |
| 0.4 | 1.1 | GO:0030519 | snoRNP binding(GO:0030519) |
| 0.3 | 4.2 | GO:0036042 | long-chain fatty acyl-CoA binding(GO:0036042) |
| 0.3 | 2.1 | GO:0004118 | cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) |
| 0.3 | 2.1 | GO:0043426 | MRF binding(GO:0043426) |
| 0.3 | 2.0 | GO:0005042 | netrin receptor activity(GO:0005042) |
| 0.3 | 1.0 | GO:0071723 | lipopeptide binding(GO:0071723) |
| 0.3 | 1.0 | GO:0051765 | inositol tetrakisphosphate kinase activity(GO:0051765) |
| 0.3 | 1.3 | GO:0004528 | phosphodiesterase I activity(GO:0004528) |
| 0.3 | 3.8 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
| 0.3 | 1.0 | GO:0008329 | signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187) |
| 0.3 | 10.0 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
| 0.3 | 1.8 | GO:0005004 | GPI-linked ephrin receptor activity(GO:0005004) |
| 0.3 | 5.0 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.3 | 4.6 | GO:0070411 | I-SMAD binding(GO:0070411) |
| 0.3 | 0.9 | GO:0001010 | transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010) |
| 0.3 | 1.4 | GO:0019770 | IgG receptor activity(GO:0019770) |
| 0.3 | 0.8 | GO:0005118 | sevenless binding(GO:0005118) |
| 0.3 | 2.6 | GO:0016151 | nickel cation binding(GO:0016151) |
| 0.3 | 1.8 | GO:0050897 | cobalt ion binding(GO:0050897) |
| 0.3 | 2.5 | GO:0070181 | small ribosomal subunit rRNA binding(GO:0070181) |
| 0.2 | 1.5 | GO:1990932 | 5.8S rRNA binding(GO:1990932) |
| 0.2 | 0.7 | GO:0004887 | thyroid hormone receptor activity(GO:0004887) |
| 0.2 | 1.6 | GO:0030619 | U1 snRNA binding(GO:0030619) |
| 0.2 | 1.9 | GO:0032051 | clathrin light chain binding(GO:0032051) |
| 0.2 | 0.9 | GO:0004459 | L-lactate dehydrogenase activity(GO:0004459) |
| 0.2 | 2.3 | GO:1990715 | mRNA CDS binding(GO:1990715) |
| 0.2 | 1.6 | GO:0001609 | G-protein coupled adenosine receptor activity(GO:0001609) |
| 0.2 | 1.5 | GO:0004614 | phosphoglucomutase activity(GO:0004614) |
| 0.2 | 1.1 | GO:0008761 | UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761) |
| 0.2 | 0.8 | GO:0016936 | galactoside binding(GO:0016936) |
| 0.2 | 2.5 | GO:0032050 | clathrin heavy chain binding(GO:0032050) |
| 0.2 | 1.2 | GO:0052654 | branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656) |
| 0.2 | 1.0 | GO:0004839 | ubiquitin activating enzyme activity(GO:0004839) |
| 0.2 | 0.9 | GO:0034235 | GPI anchor binding(GO:0034235) |
| 0.2 | 1.5 | GO:0016846 | carbon-sulfur lyase activity(GO:0016846) |
| 0.2 | 2.9 | GO:0005035 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
| 0.2 | 1.4 | GO:0016308 | 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308) |
| 0.2 | 0.7 | GO:0015143 | urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702) |
| 0.2 | 4.4 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.2 | 0.5 | GO:0080084 | polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003) RNA polymerase III type 1 promoter DNA binding(GO:0001030) RNA polymerase III type 2 promoter DNA binding(GO:0001031) 5S rDNA binding(GO:0080084) |
| 0.2 | 0.5 | GO:0008176 | tRNA (guanine-N7-)-methyltransferase activity(GO:0008176) |
| 0.2 | 3.4 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
| 0.2 | 7.7 | GO:0070888 | E-box binding(GO:0070888) |
| 0.2 | 2.7 | GO:0017134 | fibroblast growth factor binding(GO:0017134) |
| 0.2 | 6.3 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
| 0.2 | 1.6 | GO:0048406 | nerve growth factor binding(GO:0048406) |
| 0.2 | 1.4 | GO:0004185 | serine-type carboxypeptidase activity(GO:0004185) |
| 0.2 | 2.0 | GO:0030296 | protein tyrosine kinase activator activity(GO:0030296) |
| 0.2 | 1.7 | GO:0019215 | intermediate filament binding(GO:0019215) |
| 0.2 | 2.3 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
| 0.2 | 13.4 | GO:0008083 | growth factor activity(GO:0008083) |
| 0.1 | 0.9 | GO:0097001 | ceramide binding(GO:0097001) |
| 0.1 | 2.1 | GO:0031702 | angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702) |
| 0.1 | 4.4 | GO:0031369 | translation initiation factor binding(GO:0031369) |
| 0.1 | 0.4 | GO:0004813 | alanine-tRNA ligase activity(GO:0004813) |
| 0.1 | 1.8 | GO:0004576 | oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
| 0.1 | 0.6 | GO:0042134 | rRNA primary transcript binding(GO:0042134) |
| 0.1 | 0.7 | GO:0003831 | beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831) |
| 0.1 | 1.4 | GO:0001055 | RNA polymerase II activity(GO:0001055) |
| 0.1 | 1.2 | GO:0043995 | histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972) |
| 0.1 | 0.4 | GO:0017153 | sodium:dicarboxylate symporter activity(GO:0017153) |
| 0.1 | 1.7 | GO:0031681 | G-protein beta-subunit binding(GO:0031681) |
| 0.1 | 0.6 | GO:0019865 | immunoglobulin binding(GO:0019865) |
| 0.1 | 3.8 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
| 0.1 | 0.4 | GO:0030172 | troponin C binding(GO:0030172) |
| 0.1 | 1.1 | GO:0034713 | type I transforming growth factor beta receptor binding(GO:0034713) |
| 0.1 | 1.3 | GO:0005243 | gap junction channel activity(GO:0005243) |
| 0.1 | 4.3 | GO:0001671 | ATPase activator activity(GO:0001671) |
| 0.1 | 3.1 | GO:0001784 | phosphotyrosine binding(GO:0001784) |
| 0.1 | 1.2 | GO:0051575 | 5'-deoxyribose-5-phosphate lyase activity(GO:0051575) |
| 0.1 | 0.5 | GO:0031800 | type 3 metabotropic glutamate receptor binding(GO:0031800) |
| 0.1 | 0.4 | GO:0015111 | iodide transmembrane transporter activity(GO:0015111) |
| 0.1 | 1.0 | GO:0005432 | calcium:sodium antiporter activity(GO:0005432) |
| 0.1 | 1.9 | GO:0051087 | chaperone binding(GO:0051087) |
| 0.1 | 0.4 | GO:0070644 | vitamin D response element binding(GO:0070644) |
| 0.1 | 1.2 | GO:0004016 | adenylate cyclase activity(GO:0004016) |
| 0.1 | 0.9 | GO:0019956 | chemokine binding(GO:0019956) |
| 0.1 | 0.8 | GO:1990405 | protein antigen binding(GO:1990405) |
| 0.1 | 1.8 | GO:0070566 | adenylyltransferase activity(GO:0070566) |
| 0.1 | 1.0 | GO:0001161 | intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213) |
| 0.1 | 1.1 | GO:0031005 | filamin binding(GO:0031005) |
| 0.1 | 0.7 | GO:0050431 | transforming growth factor beta binding(GO:0050431) |
| 0.1 | 1.5 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
| 0.1 | 0.4 | GO:0001094 | TFIID-class transcription factor binding(GO:0001094) |
| 0.1 | 1.1 | GO:0035004 | 1-phosphatidylinositol-3-kinase activity(GO:0016303) phosphatidylinositol 3-kinase activity(GO:0035004) |
| 0.1 | 0.4 | GO:0015450 | P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450) |
| 0.1 | 0.6 | GO:0070095 | fructose-6-phosphate binding(GO:0070095) |
| 0.1 | 0.8 | GO:0050733 | pre-mRNA 3'-splice site binding(GO:0030628) RS domain binding(GO:0050733) |
| 0.1 | 0.2 | GO:0004022 | alcohol dehydrogenase (NAD) activity(GO:0004022) |
| 0.1 | 2.2 | GO:0005518 | collagen binding(GO:0005518) |
| 0.1 | 0.5 | GO:1990599 | 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599) |
| 0.1 | 5.9 | GO:0008201 | heparin binding(GO:0008201) |
| 0.1 | 3.2 | GO:0050840 | extracellular matrix binding(GO:0050840) |
| 0.1 | 3.8 | GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374) |
| 0.1 | 0.4 | GO:0000400 | four-way junction DNA binding(GO:0000400) |
| 0.1 | 2.2 | GO:0019838 | growth factor binding(GO:0019838) |
| 0.1 | 0.3 | GO:0004749 | ribose phosphate diphosphokinase activity(GO:0004749) |
| 0.1 | 0.8 | GO:0015279 | store-operated calcium channel activity(GO:0015279) |
| 0.1 | 0.4 | GO:0052629 | phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629) |
| 0.1 | 2.4 | GO:0043621 | protein self-association(GO:0043621) |
| 0.1 | 1.0 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
| 0.1 | 2.2 | GO:0004714 | transmembrane receptor protein tyrosine kinase activity(GO:0004714) |
| 0.1 | 0.7 | GO:0005355 | glucose transmembrane transporter activity(GO:0005355) |
| 0.1 | 2.7 | GO:0015485 | cholesterol binding(GO:0015485) |
| 0.1 | 2.2 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.1 | 2.7 | GO:0005484 | SNAP receptor activity(GO:0005484) |
| 0.1 | 6.7 | GO:0001191 | transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191) |
| 0.1 | 5.2 | GO:0008236 | serine-type peptidase activity(GO:0008236) |
| 0.1 | 0.2 | GO:0009881 | photoreceptor activity(GO:0009881) |
| 0.1 | 3.4 | GO:0097110 | scaffold protein binding(GO:0097110) |
| 0.1 | 1.2 | GO:0071949 | FAD binding(GO:0071949) |
| 0.1 | 0.2 | GO:0042910 | xenobiotic-transporting ATPase activity(GO:0008559) oligopeptide transmembrane transporter activity(GO:0035673) xenobiotic transporter activity(GO:0042910) sphingolipid transporter activity(GO:0046624) |
| 0.1 | 0.1 | GO:0004140 | dephospho-CoA kinase activity(GO:0004140) |
| 0.1 | 0.4 | GO:0051434 | BH3 domain binding(GO:0051434) |
| 0.0 | 0.3 | GO:0051525 | NFAT protein binding(GO:0051525) |
| 0.0 | 0.3 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
| 0.0 | 0.1 | GO:0008527 | taste receptor activity(GO:0008527) |
| 0.0 | 1.3 | GO:0019707 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
| 0.0 | 0.9 | GO:0008188 | neuropeptide receptor activity(GO:0008188) |
| 0.0 | 0.3 | GO:0015266 | protein channel activity(GO:0015266) |
| 0.0 | 0.3 | GO:1901612 | phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612) |
| 0.0 | 0.6 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
| 0.0 | 0.6 | GO:0001056 | RNA polymerase III activity(GO:0001056) |
| 0.0 | 0.9 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.0 | 0.3 | GO:0001054 | RNA polymerase I activity(GO:0001054) |
| 0.0 | 0.4 | GO:0036312 | phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312) |
| 0.0 | 0.8 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
| 0.0 | 1.1 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
| 0.0 | 1.4 | GO:0030544 | Hsp70 protein binding(GO:0030544) |
| 0.0 | 0.3 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
| 0.0 | 1.7 | GO:0031593 | polyubiquitin binding(GO:0031593) |
| 0.0 | 0.8 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 0.0 | 0.4 | GO:0003899 | DNA-directed RNA polymerase activity(GO:0003899) |
| 0.0 | 1.4 | GO:0016278 | lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279) |
| 0.0 | 0.8 | GO:0005112 | Notch binding(GO:0005112) |
| 0.0 | 0.7 | GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) |
| 0.0 | 3.8 | GO:0008237 | metallopeptidase activity(GO:0008237) |
| 0.0 | 0.8 | GO:0005080 | protein kinase C binding(GO:0005080) |
| 0.0 | 2.3 | GO:0051082 | unfolded protein binding(GO:0051082) |
| 0.0 | 0.6 | GO:0070034 | telomerase RNA binding(GO:0070034) |
| 0.0 | 0.5 | GO:0031491 | nucleosome binding(GO:0031491) |
| 0.0 | 1.0 | GO:0051059 | NF-kappaB binding(GO:0051059) |
| 0.0 | 0.4 | GO:0016866 | intramolecular transferase activity(GO:0016866) |
| 0.0 | 0.4 | GO:0036442 | hydrogen-exporting ATPase activity(GO:0036442) |
| 0.0 | 0.3 | GO:0035612 | AP-2 adaptor complex binding(GO:0035612) |
| 0.0 | 2.8 | GO:0052689 | carboxylic ester hydrolase activity(GO:0052689) |
| 0.0 | 0.5 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
| 0.0 | 0.3 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
| 0.0 | 0.1 | GO:0045236 | CXCR chemokine receptor binding(GO:0045236) |
| 0.0 | 0.6 | GO:0003785 | actin monomer binding(GO:0003785) |
| 0.0 | 1.4 | GO:0017124 | SH3 domain binding(GO:0017124) |
| 0.0 | 0.3 | GO:0015299 | solute:proton antiporter activity(GO:0015299) |
| 0.0 | 5.0 | GO:0008022 | protein C-terminus binding(GO:0008022) |
| 0.0 | 0.3 | GO:0022889 | L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889) |
| 0.0 | 5.7 | GO:0030695 | GTPase regulator activity(GO:0030695) |
| 0.0 | 1.0 | GO:0019843 | rRNA binding(GO:0019843) |
| 0.0 | 0.1 | GO:0016286 | small conductance calcium-activated potassium channel activity(GO:0016286) |
| 0.0 | 0.1 | GO:0046403 | polynucleotide 3'-phosphatase activity(GO:0046403) |
| 0.0 | 0.1 | GO:0000064 | L-ornithine transmembrane transporter activity(GO:0000064) |
| 0.0 | 0.4 | GO:0016780 | phosphotransferase activity, for other substituted phosphate groups(GO:0016780) |
| 0.0 | 0.3 | GO:0004596 | peptide alpha-N-acetyltransferase activity(GO:0004596) |
| 0.0 | 1.0 | GO:0004722 | protein serine/threonine phosphatase activity(GO:0004722) |
| 0.0 | 1.2 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.0 | 1.3 | GO:0047485 | protein N-terminus binding(GO:0047485) |
| 0.0 | 0.2 | GO:0034237 | protein kinase A regulatory subunit binding(GO:0034237) |
| 0.0 | 0.7 | GO:0051219 | phosphoprotein binding(GO:0051219) |
| 0.0 | 0.7 | GO:0044325 | ion channel binding(GO:0044325) |
| 0.0 | 0.1 | GO:0004526 | ribonuclease P activity(GO:0004526) |
| 0.0 | 0.4 | GO:0016876 | aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.0 | 10.0 | SA_MMP_CYTOKINE_CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
| 0.6 | 4.5 | SA_PTEN_PATHWAY | PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate. |
| 0.5 | 14.4 | PID_INTEGRIN_A9B1_PATHWAY | Alpha9 beta1 integrin signaling events |
| 0.5 | 15.5 | NABA_PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.4 | 83.3 | NABA_SECRETED_FACTORS | Genes encoding secreted soluble factors |
| 0.3 | 6.8 | PID_HEDGEHOG_2PATHWAY | Signaling events mediated by the Hedgehog family |
| 0.3 | 12.7 | PID_FGF_PATHWAY | FGF signaling pathway |
| 0.3 | 8.6 | ST_GA12_PATHWAY | G alpha 12 Pathway |
| 0.3 | 12.2 | SIG_IL4RECEPTOR_IN_B_LYPHOCYTES | Genes related to IL4 rceptor signaling in B lymphocytes |
| 0.3 | 11.4 | PID_SHP2_PATHWAY | SHP2 signaling |
| 0.3 | 3.2 | PID_INTEGRIN2_PATHWAY | Beta2 integrin cell surface interactions |
| 0.2 | 3.8 | PID_PI3K_PLC_TRK_PATHWAY | Trk receptor signaling mediated by PI3K and PLC-gamma |
| 0.2 | 14.5 | PID_TAP63_PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.2 | 10.4 | PID_ENDOTHELIN_PATHWAY | Endothelins |
| 0.2 | 2.4 | PID_ECADHERIN_KERATINOCYTE_PATHWAY | E-cadherin signaling in keratinocytes |
| 0.2 | 9.1 | PID_BMP_PATHWAY | BMP receptor signaling |
| 0.2 | 1.7 | PID_AR_NONGENOMIC_PATHWAY | Nongenotropic Androgen signaling |
| 0.2 | 2.6 | ST_B_CELL_ANTIGEN_RECEPTOR | B Cell Antigen Receptor |
| 0.2 | 0.4 | SA_TRKA_RECEPTOR | The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth. |
| 0.2 | 22.8 | NABA_ECM_AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.2 | 0.2 | PID_S1P_S1P1_PATHWAY | S1P1 pathway |
| 0.2 | 2.2 | ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY | PI3K Pathway |
| 0.1 | 3.1 | PID_ALPHA_SYNUCLEIN_PATHWAY | Alpha-synuclein signaling |
| 0.1 | 3.2 | PID_IL2_STAT5_PATHWAY | IL2 signaling events mediated by STAT5 |
| 0.1 | 5.0 | PID_CDC42_REG_PATHWAY | Regulation of CDC42 activity |
| 0.1 | 12.0 | PID_PDGFRB_PATHWAY | PDGFR-beta signaling pathway |
| 0.1 | 5.5 | PID_TCR_PATHWAY | TCR signaling in naïve CD4+ T cells |
| 0.1 | 18.4 | NABA_ECM_GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.1 | 2.8 | PID_PTP1B_PATHWAY | Signaling events mediated by PTP1B |
| 0.1 | 5.3 | PID_ERBB1_INTERNALIZATION_PATHWAY | Internalization of ErbB1 |
| 0.1 | 4.4 | PID_BARD1_PATHWAY | BARD1 signaling events |
| 0.1 | 9.2 | PID_HIF1_TFPATHWAY | HIF-1-alpha transcription factor network |
| 0.1 | 1.8 | PID_EPHA_FWDPATHWAY | EPHA forward signaling |
| 0.1 | 2.1 | PID_MYC_PATHWAY | C-MYC pathway |
| 0.1 | 1.5 | PID_TRAIL_PATHWAY | TRAIL signaling pathway |
| 0.1 | 2.0 | PID_MET_PATHWAY | Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) |
| 0.1 | 2.5 | PID_ARF_3PATHWAY | Arf1 pathway |
| 0.1 | 5.5 | PID_RHOA_REG_PATHWAY | Regulation of RhoA activity |
| 0.1 | 3.3 | PID_RXR_VDR_PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
| 0.1 | 4.6 | PID_MYC_REPRESS_PATHWAY | Validated targets of C-MYC transcriptional repression |
| 0.1 | 1.0 | PID_PI3KCI_AKT_PATHWAY | Class I PI3K signaling events mediated by Akt |
| 0.1 | 4.6 | PID_LKB1_PATHWAY | LKB1 signaling events |
| 0.1 | 1.1 | PID_TOLL_ENDOGENOUS_PATHWAY | Endogenous TLR signaling |
| 0.1 | 3.6 | PID_AR_PATHWAY | Coregulation of Androgen receptor activity |
| 0.1 | 2.2 | PID_AR_TF_PATHWAY | Regulation of Androgen receptor activity |
| 0.1 | 3.5 | PID_BETA_CATENIN_NUC_PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
| 0.1 | 1.3 | PID_TNF_PATHWAY | TNF receptor signaling pathway |
| 0.1 | 2.6 | PID_CASPASE_PATHWAY | Caspase cascade in apoptosis |
| 0.1 | 1.0 | PID_IL6_7_PATHWAY | IL6-mediated signaling events |
| 0.1 | 1.1 | PID_HIF2PATHWAY | HIF-2-alpha transcription factor network |
| 0.1 | 2.7 | PID_REG_GR_PATHWAY | Glucocorticoid receptor regulatory network |
| 0.1 | 2.9 | PID_ERA_GENOMIC_PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.1 | 1.0 | PID_HNF3A_PATHWAY | FOXA1 transcription factor network |
| 0.0 | 0.8 | PID_CIRCADIAN_PATHWAY | Circadian rhythm pathway |
| 0.0 | 2.2 | PID_P53_REGULATION_PATHWAY | p53 pathway |
| 0.0 | 0.2 | PID_AMB2_NEUTROPHILS_PATHWAY | amb2 Integrin signaling |
| 0.0 | 0.9 | PID_TCR_CALCIUM_PATHWAY | Calcium signaling in the CD4+ TCR pathway |
| 0.0 | 0.6 | SIG_CD40PATHWAYMAP | Genes related to CD40 signaling |
| 0.0 | 0.3 | PID_MAPK_TRK_PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
| 0.0 | 0.4 | PID_INTEGRIN_A4B1_PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.0 | 0.2 | PID_ERBB2_ERBB3_PATHWAY | ErbB2/ErbB3 signaling events |
| 0.0 | 0.5 | PID_DNA_PK_PATHWAY | DNA-PK pathway in nonhomologous end joining |
| 0.0 | 1.0 | PID_CMYB_PATHWAY | C-MYB transcription factor network |
| 0.0 | 0.8 | PID_TELOMERASE_PATHWAY | Regulation of Telomerase |
| 0.0 | 0.2 | ST_WNT_BETA_CATENIN_PATHWAY | Wnt/beta-catenin Pathway |
| 0.0 | 1.4 | NABA_ECM_REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.0 | 0.5 | WNT_SIGNALING | Genes related to Wnt-mediated signal transduction |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.1 | 16.4 | REACTOME_REGULATION_OF_COMPLEMENT_CASCADE | Genes involved in Regulation of Complement cascade |
| 3.5 | 21.3 | REACTOME_COMMON_PATHWAY | Genes involved in Common Pathway |
| 3.1 | 18.5 | REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS | Genes involved in Creation of C4 and C2 activators |
| 2.2 | 19.5 | REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR | Genes involved in Trafficking and processing of endosomal TLR |
| 1.6 | 37.4 | REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 1.0 | 4.2 | REACTOME_GLYCOPROTEIN_HORMONES | Genes involved in Glycoprotein hormones |
| 1.0 | 16.5 | REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| 0.8 | 14.4 | REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
| 0.8 | 7.9 | REACTOME_KERATAN_SULFATE_DEGRADATION | Genes involved in Keratan sulfate degradation |
| 0.8 | 5.4 | REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES | Genes involved in Cytosolic sulfonation of small molecules |
| 0.7 | 7.5 | REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS | Genes involved in G alpha (z) signalling events |
| 0.6 | 6.4 | REACTOME_SIGNALING_BY_ACTIVATED_POINT_MUTANTS_OF_FGFR1 | Genes involved in Signaling by activated point mutants of FGFR1 |
| 0.6 | 17.1 | REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING | Genes involved in DCC mediated attractive signaling |
| 0.6 | 12.2 | REACTOME_SOS_MEDIATED_SIGNALLING | Genes involved in SOS-mediated signalling |
| 0.5 | 3.8 | REACTOME_THE_NLRP3_INFLAMMASOME | Genes involved in The NLRP3 inflammasome |
| 0.5 | 6.7 | REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
| 0.5 | 14.0 | REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS | Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis |
| 0.4 | 4.5 | REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS | Genes involved in Signal regulatory protein (SIRP) family interactions |
| 0.4 | 9.2 | REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
| 0.4 | 10.9 | REACTOME_GLUTATHIONE_CONJUGATION | Genes involved in Glutathione conjugation |
| 0.4 | 4.8 | REACTOME_CS_DS_DEGRADATION | Genes involved in CS/DS degradation |
| 0.3 | 7.3 | REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION | Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation |
| 0.3 | 9.2 | REACTOME_CA_DEPENDENT_EVENTS | Genes involved in Ca-dependent events |
| 0.3 | 7.7 | REACTOME_DARPP_32_EVENTS | Genes involved in DARPP-32 events |
| 0.3 | 6.4 | REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION | Genes involved in GABA synthesis, release, reuptake and degradation |
| 0.3 | 7.9 | REACTOME_RAP1_SIGNALLING | Genes involved in Rap1 signalling |
| 0.3 | 2.7 | REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
| 0.3 | 3.4 | REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |
| 0.3 | 3.4 | REACTOME_HDL_MEDIATED_LIPID_TRANSPORT | Genes involved in HDL-mediated lipid transport |
| 0.3 | 10.6 | REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES | Genes involved in Transport of vitamins, nucleosides, and related molecules |
| 0.2 | 3.4 | REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE | Genes involved in Beta-catenin phosphorylation cascade |
| 0.2 | 2.7 | REACTOME_IL_7_SIGNALING | Genes involved in Interleukin-7 signaling |
| 0.2 | 8.4 | REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES | Genes involved in Ion transport by P-type ATPases |
| 0.2 | 4.1 | REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS | Genes involved in ABCA transporters in lipid homeostasis |
| 0.2 | 5.1 | REACTOME_SIGNALING_BY_PDGF | Genes involved in Signaling by PDGF |
| 0.2 | 2.0 | REACTOME_MRNA_DECAY_BY_3_TO_5_EXORIBONUCLEASE | Genes involved in mRNA Decay by 3' to 5' Exoribonuclease |
| 0.2 | 5.0 | REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 0.2 | 1.4 | REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
| 0.2 | 1.0 | REACTOME_PLATELET_CALCIUM_HOMEOSTASIS | Genes involved in Platelet calcium homeostasis |
| 0.2 | 1.5 | REACTOME_PLC_BETA_MEDIATED_EVENTS | Genes involved in PLC beta mediated events |
| 0.2 | 2.0 | REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS | Genes involved in Role of DCC in regulating apoptosis |
| 0.2 | 2.8 | REACTOME_MTORC1_MEDIATED_SIGNALLING | Genes involved in mTORC1-mediated signalling |
| 0.2 | 6.5 | REACTOME_GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
| 0.2 | 4.0 | REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS | Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers |
| 0.2 | 6.8 | REACTOME_GLUCOSE_TRANSPORT | Genes involved in Glucose transport |
| 0.1 | 7.9 | REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
| 0.1 | 4.2 | REACTOME_SIGNALING_BY_BMP | Genes involved in Signaling by BMP |
| 0.1 | 13.4 | REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
| 0.1 | 2.5 | REACTOME_GAP_JUNCTION_DEGRADATION | Genes involved in Gap junction degradation |
| 0.1 | 1.1 | REACTOME_TRAF6_MEDIATED_INDUCTION_OF_TAK1_COMPLEX | Genes involved in TRAF6 mediated induction of TAK1 complex |
| 0.1 | 1.9 | REACTOME_METABOLISM_OF_POLYAMINES | Genes involved in Metabolism of polyamines |
| 0.1 | 1.6 | REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS | Genes involved in Nucleotide-like (purinergic) receptors |
| 0.1 | 2.1 | REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS | Genes involved in Processing of Intronless Pre-mRNAs |
| 0.1 | 1.5 | REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR | Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor |
| 0.1 | 2.3 | REACTOME_RNA_POL_III_CHAIN_ELONGATION | Genes involved in RNA Polymerase III Chain Elongation |
| 0.1 | 1.4 | REACTOME_SIGNALING_BY_NODAL | Genes involved in Signaling by NODAL |
| 0.1 | 2.1 | REACTOME_CGMP_EFFECTS | Genes involved in cGMP effects |
| 0.1 | 2.5 | REACTOME_METABOLISM_OF_NON_CODING_RNA | Genes involved in Metabolism of non-coding RNA |
| 0.1 | 1.1 | REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER | Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter |
| 0.1 | 1.7 | REACTOME_GABA_A_RECEPTOR_ACTIVATION | Genes involved in GABA A receptor activation |
| 0.1 | 1.2 | REACTOME_COPI_MEDIATED_TRANSPORT | Genes involved in COPI Mediated Transport |
| 0.1 | 3.6 | REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING | Genes involved in Sema4D in semaphorin signaling |
| 0.1 | 1.6 | REACTOME_INTEGRATION_OF_PROVIRUS | Genes involved in Integration of provirus |
| 0.1 | 3.4 | REACTOME_INTERFERON_ALPHA_BETA_SIGNALING | Genes involved in Interferon alpha/beta signaling |
| 0.1 | 5.1 | REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
| 0.1 | 3.8 | REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS | Genes involved in Voltage gated Potassium channels |
| 0.1 | 0.9 | REACTOME_ACYL_CHAIN_REMODELLING_OF_PG | Genes involved in Acyl chain remodelling of PG |
| 0.1 | 3.8 | REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
| 0.1 | 5.6 | REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ | Genes involved in Response to elevated platelet cytosolic Ca2+ |
| 0.1 | 12.4 | REACTOME_SIGNALING_BY_RHO_GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.1 | 3.8 | REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT | Genes involved in Mitochondrial Protein Import |
| 0.1 | 1.1 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE | Genes involved in Synthesis of PIPs at the early endosome membrane |
| 0.1 | 1.7 | REACTOME_SYNTHESIS_OF_PC | Genes involved in Synthesis of PC |
| 0.1 | 4.9 | REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.1 | 0.6 | REACTOME_NFKB_IS_ACTIVATED_AND_SIGNALS_SURVIVAL | Genes involved in NF-kB is activated and signals survival |
| 0.1 | 1.7 | REACTOME_INTERFERON_GAMMA_SIGNALING | Genes involved in Interferon gamma signaling |
| 0.1 | 1.1 | REACTOME_CRMPS_IN_SEMA3A_SIGNALING | Genes involved in CRMPs in Sema3A signaling |
| 0.1 | 3.0 | REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
| 0.1 | 1.1 | REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN | Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin |
| 0.1 | 0.4 | REACTOME_INFLAMMASOMES | Genes involved in Inflammasomes |
| 0.1 | 4.2 | REACTOME_RESPIRATORY_ELECTRON_TRANSPORT | Genes involved in Respiratory electron transport |
| 0.1 | 2.6 | REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS | Genes involved in Apoptotic cleavage of cellular proteins |
| 0.1 | 1.2 | REACTOME_FANCONI_ANEMIA_PATHWAY | Genes involved in Fanconi Anemia pathway |
| 0.1 | 0.6 | REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC | Genes involved in Formation of tubulin folding intermediates by CCT/TriC |
| 0.0 | 4.2 | REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION | Genes involved in MHC class II antigen presentation |
| 0.0 | 0.5 | REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC | Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC |
| 0.0 | 0.8 | REACTOME_KERATAN_SULFATE_BIOSYNTHESIS | Genes involved in Keratan sulfate biosynthesis |
| 0.0 | 0.4 | REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
| 0.0 | 1.1 | REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING | Genes involved in Negative regulators of RIG-I/MDA5 signaling |
| 0.0 | 2.3 | REACTOME_COLLAGEN_FORMATION | Genes involved in Collagen formation |
| 0.0 | 0.8 | REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
| 0.0 | 0.5 | REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE | Genes involved in Cytochrome P450 - arranged by substrate type |
| 0.0 | 0.5 | REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
| 0.0 | 0.6 | REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
| 0.0 | 0.4 | REACTOME_P38MAPK_EVENTS | Genes involved in p38MAPK events |
| 0.0 | 0.7 | REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS | Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis |
| 0.0 | 0.2 | REACTOME_RIG_I_MDA5_MEDIATED_INDUCTION_OF_IFN_ALPHA_BETA_PATHWAYS | Genes involved in RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways |
| 0.0 | 0.4 | REACTOME_PYRUVATE_METABOLISM | Genes involved in Pyruvate metabolism |
| 0.0 | 0.7 | REACTOME_SYNTHESIS_OF_PA | Genes involved in Synthesis of PA |
| 0.0 | 2.1 | REACTOME_NONSENSE_MEDIATED_DECAY_ENHANCED_BY_THE_EXON_JUNCTION_COMPLEX | Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex |
| 0.0 | 1.8 | REACTOME_ASPARAGINE_N_LINKED_GLYCOSYLATION | Genes involved in Asparagine N-linked glycosylation |
| 0.0 | 0.4 | REACTOME_ERK_MAPK_TARGETS | Genes involved in ERK/MAPK targets |
| 0.0 | 0.7 | REACTOME_POST_TRANSLATIONAL_MODIFICATION_SYNTHESIS_OF_GPI_ANCHORED_PROTEINS | Genes involved in Post-translational modification: synthesis of GPI-anchored proteins |
| 0.0 | 0.3 | REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS | Genes involved in Glycogen breakdown (glycogenolysis) |
| 0.0 | 0.6 | REACTOME_EXTENSION_OF_TELOMERES | Genes involved in Extension of Telomeres |
| 0.0 | 1.3 | REACTOME_G_ALPHA_S_SIGNALLING_EVENTS | Genes involved in G alpha (s) signalling events |
| 0.0 | 0.2 | REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT | Genes involved in ABC-family proteins mediated transport |
| 0.0 | 0.4 | REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION | Genes involved in Mitochondrial tRNA aminoacylation |
| 0.0 | 0.2 | REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
| 0.0 | 0.2 | REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
| 0.0 | 0.2 | REACTOME_PYRUVATE_METABOLISM_AND_CITRIC_ACID_TCA_CYCLE | Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle |
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