Motif ID: Scrt1
Z-value: 1.396

Transcription factors associated with Scrt1:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Scrt1 | ENSMUSG00000048385.8 | Scrt1 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Scrt1 | mm10_v2_chr15_-_76521902_76522129 | -0.21 | 6.6e-02 | Click! |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 117 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.1 | 35.7 | GO:0030953 | astral microtubule organization(GO:0030953) |
5.6 | 16.9 | GO:0071579 | regulation of zinc ion transport(GO:0071579) |
5.5 | 16.6 | GO:1904274 | tricellular tight junction assembly(GO:1904274) |
5.2 | 15.7 | GO:0061349 | Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333) hypophysis morphogenesis(GO:0048850) cervix development(GO:0060067) planar cell polarity pathway involved in outflow tract morphogenesis(GO:0061347) planar cell polarity pathway involved in ventricular septum morphogenesis(GO:0061348) planar cell polarity pathway involved in cardiac right atrium morphogenesis(GO:0061349) planar cell polarity pathway involved in cardiac muscle tissue morphogenesis(GO:0061350) planar cell polarity pathway involved in pericardium morphogenesis(GO:0061354) |
0.5 | 15.3 | GO:0097150 | neuronal stem cell population maintenance(GO:0097150) |
1.1 | 14.3 | GO:0035881 | amacrine cell differentiation(GO:0035881) |
1.5 | 13.7 | GO:0002318 | myeloid progenitor cell differentiation(GO:0002318) |
2.7 | 13.6 | GO:0032901 | positive regulation of neurotrophin production(GO:0032901) |
0.1 | 13.2 | GO:0051592 | response to calcium ion(GO:0051592) |
0.9 | 12.3 | GO:1901741 | positive regulation of myoblast fusion(GO:1901741) |
2.9 | 11.6 | GO:0006982 | response to lipid hydroperoxide(GO:0006982) cellular response to lipid hydroperoxide(GO:0071449) |
2.2 | 11.0 | GO:0048852 | diencephalon morphogenesis(GO:0048852) |
0.1 | 11.0 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
2.7 | 10.9 | GO:0010637 | negative regulation of mitochondrial fusion(GO:0010637) |
1.7 | 10.0 | GO:0032483 | regulation of Rab protein signal transduction(GO:0032483) |
3.3 | 9.9 | GO:0051464 | positive regulation of cortisol secretion(GO:0051464) |
2.5 | 9.8 | GO:0038128 | ERBB2 signaling pathway(GO:0038128) |
1.5 | 9.3 | GO:0003383 | apical constriction(GO:0003383) |
0.7 | 9.3 | GO:0021891 | olfactory bulb interneuron development(GO:0021891) |
0.9 | 9.0 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 71 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 35.5 | GO:0005813 | centrosome(GO:0005813) |
0.1 | 27.4 | GO:0044798 | nuclear transcription factor complex(GO:0044798) |
0.1 | 21.3 | GO:0055037 | recycling endosome(GO:0055037) |
0.0 | 20.9 | GO:0005887 | integral component of plasma membrane(GO:0005887) |
0.2 | 19.4 | GO:0005778 | peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903) |
2.8 | 16.6 | GO:0061689 | tricellular tight junction(GO:0061689) |
2.7 | 13.7 | GO:0033010 | paranodal junction(GO:0033010) |
0.2 | 13.6 | GO:0005776 | autophagosome(GO:0005776) |
0.0 | 11.6 | GO:0005925 | focal adhesion(GO:0005925) |
0.3 | 11.0 | GO:0060077 | inhibitory synapse(GO:0060077) |
0.1 | 10.6 | GO:0000786 | nucleosome(GO:0000786) |
0.0 | 10.3 | GO:0005681 | spliceosomal complex(GO:0005681) |
1.2 | 9.3 | GO:0033269 | internode region of axon(GO:0033269) |
1.1 | 9.1 | GO:0005664 | origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664) |
0.8 | 8.6 | GO:0032426 | stereocilium tip(GO:0032426) |
0.1 | 8.4 | GO:0005741 | mitochondrial outer membrane(GO:0005741) |
0.1 | 8.2 | GO:0016605 | PML body(GO:0016605) |
0.0 | 8.1 | GO:0000790 | nuclear chromatin(GO:0000790) |
0.1 | 7.8 | GO:0005871 | kinesin complex(GO:0005871) |
0.2 | 6.9 | GO:0090544 | BAF-type complex(GO:0090544) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 85 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 61.1 | GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) |
0.5 | 22.4 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
0.4 | 18.9 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
0.6 | 16.9 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
0.7 | 16.4 | GO:0098632 | protein binding involved in cell-cell adhesion(GO:0098632) |
0.0 | 15.8 | GO:0019904 | protein domain specific binding(GO:0019904) |
5.2 | 15.7 | GO:0005110 | frizzled-2 binding(GO:0005110) |
0.8 | 14.4 | GO:0030169 | low-density lipoprotein particle binding(GO:0030169) |
0.1 | 14.3 | GO:0001158 | enhancer sequence-specific DNA binding(GO:0001158) |
1.7 | 13.6 | GO:0048403 | brain-derived neurotrophic factor binding(GO:0048403) |
0.6 | 11.7 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
0.5 | 11.6 | GO:0004602 | glutathione peroxidase activity(GO:0004602) |
0.1 | 10.5 | GO:0008186 | RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186) |
2.5 | 9.9 | GO:0004966 | galanin receptor activity(GO:0004966) |
0.5 | 9.4 | GO:0035198 | miRNA binding(GO:0035198) |
0.2 | 9.3 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
2.3 | 9.1 | GO:0046920 | alpha-(1->3)-fucosyltransferase activity(GO:0046920) |
0.6 | 9.1 | GO:0003688 | DNA replication origin binding(GO:0003688) |
0.0 | 8.9 | GO:0016491 | oxidoreductase activity(GO:0016491) |
0.7 | 8.6 | GO:0017081 | chloride channel regulator activity(GO:0017081) |
Gene overrepresentation in C2:CP category:
Showing 1 to 20 of 28 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.8 | 34.4 | PID_AURORA_A_PATHWAY | Aurora A signaling |
0.6 | 28.0 | PID_WNT_NONCANONICAL_PATHWAY | Noncanonical Wnt signaling pathway |
0.7 | 14.0 | PID_P38_GAMMA_DELTA_PATHWAY | Signaling mediated by p38-gamma and p38-delta |
1.0 | 13.7 | PID_INTEGRIN2_PATHWAY | Beta2 integrin cell surface interactions |
0.3 | 9.3 | PID_PRL_SIGNALING_EVENTS_PATHWAY | Signaling events mediated by PRL |
0.2 | 9.0 | PID_ATR_PATHWAY | ATR signaling pathway |
0.1 | 8.9 | SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES | Genes related to the insulin receptor pathway |
0.1 | 8.6 | PID_TXA2PATHWAY | Thromboxane A2 receptor signaling |
0.0 | 7.7 | NABA_SECRETED_FACTORS | Genes encoding secreted soluble factors |
0.1 | 7.5 | PID_RAC1_REG_PATHWAY | Regulation of RAC1 activity |
0.1 | 4.0 | PID_HDAC_CLASSIII_PATHWAY | Signaling events mediated by HDAC Class III |
0.1 | 3.8 | PID_FANCONI_PATHWAY | Fanconi anemia pathway |
0.1 | 3.1 | PID_IL12_STAT4_PATHWAY | IL12 signaling mediated by STAT4 |
0.0 | 3.1 | PID_ERA_GENOMIC_PATHWAY | Validated nuclear estrogen receptor alpha network |
0.1 | 3.0 | PID_NEPHRIN_NEPH1_PATHWAY | Nephrin/Neph1 signaling in the kidney podocyte |
0.0 | 2.7 | PID_TELOMERASE_PATHWAY | Regulation of Telomerase |
0.0 | 2.7 | NABA_ECM_REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
0.1 | 2.5 | PID_RXR_VDR_PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
0.0 | 2.4 | PID_SMAD2_3NUCLEAR_PATHWAY | Regulation of nuclear SMAD2/3 signaling |
0.0 | 1.6 | PID_P53_DOWNSTREAM_PATHWAY | Direct p53 effectors |
Gene overrepresentation in C2:CP:REACTOME category:
Showing 1 to 20 of 34 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 15.7 | REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
0.2 | 13.7 | REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS | Genes involved in Integrin cell surface interactions |
0.6 | 12.2 | REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION | Genes involved in TRAF6 mediated IRF7 activation |
0.4 | 11.6 | REACTOME_GLUTATHIONE_CONJUGATION | Genes involved in Glutathione conjugation |
0.7 | 10.5 | REACTOME_UNWINDING_OF_DNA | Genes involved in Unwinding of DNA |
0.4 | 10.4 | REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION | Genes involved in Pre-NOTCH Transcription and Translation |
0.3 | 9.3 | REACTOME_TIGHT_JUNCTION_INTERACTIONS | Genes involved in Tight junction interactions |
0.1 | 7.6 | REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS | Genes involved in Peptide ligand-binding receptors |
0.2 | 6.5 | REACTOME_PACKAGING_OF_TELOMERE_ENDS | Genes involved in Packaging Of Telomere Ends |
0.0 | 6.1 | REACTOME_SIGNALING_BY_RHO_GTPASES | Genes involved in Signaling by Rho GTPases |
0.1 | 4.7 | REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
0.4 | 3.8 | REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY | Genes involved in Regulation of the Fanconi anemia pathway |
0.1 | 3.7 | REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS | Genes involved in O-linked glycosylation of mucins |
0.0 | 3.7 | REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES | Genes involved in Metabolism of amino acids and derivatives |
0.2 | 3.2 | REACTOME_SULFUR_AMINO_ACID_METABOLISM | Genes involved in Sulfur amino acid metabolism |
0.4 | 3.0 | REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS | Genes involved in Apoptotic cleavage of cell adhesion proteins |
0.1 | 2.8 | REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION | Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription |
0.0 | 2.2 | REACTOME_COLLAGEN_FORMATION | Genes involved in Collagen formation |
0.0 | 2.0 | REACTOME_PEPTIDE_CHAIN_ELONGATION | Genes involved in Peptide chain elongation |
0.1 | 1.9 | REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_2_PROMOTER | Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter |