Motif ID: Scrt1

Z-value: 1.396


Transcription factors associated with Scrt1:

Gene SymbolEntrez IDGene Name
Scrt1 ENSMUSG00000048385.8 Scrt1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Scrt1mm10_v2_chr15_-_76521902_76522129-0.216.6e-02Click!


Activity profile for motif Scrt1.

activity profile for motif Scrt1


Sorted Z-values histogram for motif Scrt1

Sorted Z-values for motif Scrt1



Network of associatons between targets according to the STRING database.



First level regulatory network of Scrt1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_185454803 16.887 ENSMUST00000061093.6
Slc30a10
solute carrier family 30, member 10
chr14_+_28511344 15.677 ENSMUST00000112272.1
Wnt5a
wingless-related MMTV integration site 5A
chr5_-_114273702 14.296 ENSMUST00000144050.1
ENSMUST00000044790.5
Foxn4

forkhead box N4

chr5_+_33658567 13.891 ENSMUST00000114426.3
Tacc3
transforming, acidic coiled-coil containing protein 3
chr9_+_91368811 13.801 ENSMUST00000173054.1
Zic4
zinc finger protein of the cerebellum 4
chr9_-_27155418 13.715 ENSMUST00000167074.1
ENSMUST00000034472.8
Jam3

junction adhesion molecule 3

chr11_-_100355383 13.568 ENSMUST00000146878.2
Hap1
huntingtin-associated protein 1
chr9_+_91368970 13.130 ENSMUST00000172646.1
Zic4
zinc finger protein of the cerebellum 4
chr6_+_128375456 12.684 ENSMUST00000100926.2
4933413G19Rik
RIKEN cDNA 4933413G19 gene
chr6_+_138140521 11.603 ENSMUST00000120939.1
ENSMUST00000120302.1
Mgst1

microsomal glutathione S-transferase 1

chr5_+_33658550 11.301 ENSMUST00000152847.1
Tacc3
transforming, acidic coiled-coil containing protein 3
chr3_+_34649987 11.040 ENSMUST00000099151.2
Sox2
SRY-box containing gene 2
chr11_-_101466222 10.858 ENSMUST00000040430.7
Vat1
vesicle amine transport protein 1 homolog (T californica)
chr5_+_33658123 10.501 ENSMUST00000074849.6
ENSMUST00000079534.4
Tacc3

transforming, acidic coiled-coil containing protein 3

chr18_-_82406777 9.874 ENSMUST00000065224.6
Galr1
galanin receptor 1
chr4_-_19570073 9.814 ENSMUST00000029885.4
Cpne3
copine III
chr10_+_26229707 9.541 ENSMUST00000060716.5
ENSMUST00000164660.1
Samd3

sterile alpha motif domain containing 3

chr7_-_44815658 9.318 ENSMUST00000107893.1
Atf5
activating transcription factor 5
chr8_+_127064107 9.277 ENSMUST00000162536.1
ENSMUST00000026921.6
ENSMUST00000162665.1
ENSMUST00000160766.1
ENSMUST00000162602.1
ENSMUST00000162531.1
ENSMUST00000160581.1
ENSMUST00000161355.1
ENSMUST00000159537.1
Pard3








par-3 (partitioning defective 3) homolog (C. elegans)








chr6_-_88898664 9.100 ENSMUST00000058011.6
Mcm2
minichromosome maintenance deficient 2 mitotin (S. cerevisiae)
chr8_+_31187317 9.073 ENSMUST00000066173.5
ENSMUST00000161788.1
ENSMUST00000110527.2
ENSMUST00000161502.1
Fut10



fucosyltransferase 10



chr9_-_96862903 8.949 ENSMUST00000121077.1
ENSMUST00000124923.1
Acpl2

acid phosphatase-like 2

chr13_-_23991158 8.887 ENSMUST00000021770.7
Scgn
secretagogin, EF-hand calcium binding protein
chr2_+_92915080 8.622 ENSMUST00000028648.2
Syt13
synaptotagmin XIII
chr11_+_115163333 8.597 ENSMUST00000021077.3
Slc9a3r1
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
chr14_+_32028989 8.000 ENSMUST00000022460.4
Galnt15
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 15
chr4_-_116123618 7.968 ENSMUST00000102704.3
ENSMUST00000102705.3
Rad54l

RAD54 like (S. cerevisiae)

chr7_+_110221697 7.840 ENSMUST00000033325.7
Swap70
SWA-70 protein
chr2_+_131234043 7.794 ENSMUST00000041362.5
ENSMUST00000110199.2
Mavs

mitochondrial antiviral signaling protein

chr2_+_72285637 7.649 ENSMUST00000090824.5
ENSMUST00000135469.1
Zak

sterile alpha motif and leucine zipper containing kinase AZK

chr13_-_81633119 7.537 ENSMUST00000126444.1
ENSMUST00000128585.1
ENSMUST00000146749.1
ENSMUST00000095585.4
Gpr98



G protein-coupled receptor 98



chr14_+_60634719 7.490 ENSMUST00000022566.7
ENSMUST00000159729.1
Spata13

spermatogenesis associated 13

chr1_-_87156127 7.427 ENSMUST00000160810.1
Ecel1
endothelin converting enzyme-like 1
chr3_+_90537306 7.113 ENSMUST00000107335.1
S100a16
S100 calcium binding protein A16
chr3_+_90537242 7.065 ENSMUST00000098911.3
S100a16
S100 calcium binding protein A16
chr17_+_26917091 6.885 ENSMUST00000078961.4
Kifc5b
kinesin family member C5B
chr7_-_30973367 6.545 ENSMUST00000108116.3
Lsr
lipolysis stimulated lipoprotein receptor
chr5_-_137116177 6.534 ENSMUST00000054384.5
ENSMUST00000152207.1
Trim56

tripartite motif-containing 56

chr11_-_6444352 6.460 ENSMUST00000093346.5
ENSMUST00000109737.2
H2afv

H2A histone family, member V

chr7_-_144939823 6.387 ENSMUST00000093962.4
Ccnd1
cyclin D1
chr2_-_168590315 6.353 ENSMUST00000109184.1
Nfatc2
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2
chr18_-_14682756 6.238 ENSMUST00000040964.6
ENSMUST00000092041.3
ENSMUST00000040924.7
Ss18


synovial sarcoma translocation, Chromosome 18


chr2_-_168590191 5.972 ENSMUST00000029057.6
ENSMUST00000074618.3
Nfatc2

nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2

chr1_-_173942445 5.848 ENSMUST00000042228.8
ENSMUST00000081216.5
ENSMUST00000129829.1
ENSMUST00000123708.1
ENSMUST00000111210.2
Ifi203



Mndal
interferon activated gene 203



myeloid nuclear differentiation antigen like
chr1_+_172482199 5.557 ENSMUST00000135267.1
ENSMUST00000052629.6
ENSMUST00000111235.2
Igsf9


immunoglobulin superfamily, member 9


chr7_-_30973399 5.513 ENSMUST00000098553.4
ENSMUST00000147431.1
Lsr

lipolysis stimulated lipoprotein receptor

chr5_+_137630116 5.474 ENSMUST00000175968.1
Lrch4
leucine-rich repeats and calponin homology (CH) domain containing 4
chr2_-_38287347 5.455 ENSMUST00000102787.3
Dennd1a
DENN/MADD domain containing 1A
chr1_+_172481788 5.430 ENSMUST00000127052.1
Igsf9
immunoglobulin superfamily, member 9
chr3_+_121426495 5.371 ENSMUST00000029773.8
Cnn3
calponin 3, acidic
chr14_-_72709534 5.259 ENSMUST00000162478.1
Fndc3a
fibronectin type III domain containing 3A
chr17_-_25570678 5.074 ENSMUST00000025003.3
ENSMUST00000173447.1
Sox8

SRY-box containing gene 8

chr14_+_26579535 4.823 ENSMUST00000037585.7
Dennd6a
DENN/MADD domain containing 6A
chr6_-_120357422 4.740 ENSMUST00000032283.5
Ccdc77
coiled-coil domain containing 77
chr7_-_44669308 4.700 ENSMUST00000148487.1
Myh14
myosin, heavy polypeptide 14
chr6_-_120357440 4.675 ENSMUST00000112703.1
Ccdc77
coiled-coil domain containing 77
chr7_-_30973464 4.588 ENSMUST00000001279.8
Lsr
lipolysis stimulated lipoprotein receptor
chr12_-_91779129 4.586 ENSMUST00000170077.1
Ston2
stonin 2
chr2_-_38287174 4.498 ENSMUST00000130472.1
Dennd1a
DENN/MADD domain containing 1A
chr7_-_133776772 4.377 ENSMUST00000033290.5
Dhx32
DEAH (Asp-Glu-Ala-His) box polypeptide 32
chr2_-_127788854 4.364 ENSMUST00000028857.7
ENSMUST00000110357.1
Nphp1

nephronophthisis 1 (juvenile) homolog (human)

chr9_-_108578657 4.233 ENSMUST00000068700.5
Wdr6
WD repeat domain 6
chr2_-_170142673 4.191 ENSMUST00000109155.1
Zfp217
zinc finger protein 217
chr13_+_23756937 4.163 ENSMUST00000102965.2
Hist1h4b
histone cluster 1, H4b
chr6_-_120357342 4.108 ENSMUST00000163827.1
Ccdc77
coiled-coil domain containing 77
chrX_-_133981765 4.104 ENSMUST00000113297.2
ENSMUST00000174542.1
ENSMUST00000033608.8
ENSMUST00000113294.1
Sytl4



synaptotagmin-like 4



chr17_+_53584124 4.030 ENSMUST00000164390.1
Kat2b
K(lysine) acetyltransferase 2B
chr3_-_57301919 4.029 ENSMUST00000029376.8
Tm4sf1
transmembrane 4 superfamily member 1
chr7_-_133776681 4.013 ENSMUST00000130182.1
ENSMUST00000106139.1
Dhx32

DEAH (Asp-Glu-Ala-His) box polypeptide 32

chr15_-_66500857 4.005 ENSMUST00000023006.6
Lrrc6
leucine rich repeat containing 6 (testis)
chr12_-_85339346 3.944 ENSMUST00000040992.7
Nek9
NIMA (never in mitosis gene a)-related expressed kinase 9
chrX_+_169879596 3.935 ENSMUST00000112105.1
ENSMUST00000078947.5
Mid1

midline 1

chr19_-_5912834 3.932 ENSMUST00000136983.1
Dpf2
D4, zinc and double PHD fingers family 2
chr17_-_25844417 3.697 ENSMUST00000176591.1
Rhot2
ras homolog gene family, member T2
chr19_-_24861828 3.615 ENSMUST00000047666.4
Pgm5
phosphoglucomutase 5
chr3_+_88325023 3.547 ENSMUST00000177005.1
0610031J06Rik
RIKEN cDNA 0610031J06 gene
chr8_+_71488103 3.525 ENSMUST00000007754.6
ENSMUST00000168847.1
Gtpbp3

GTP binding protein 3

chr9_+_59656368 3.507 ENSMUST00000034834.9
ENSMUST00000163694.2
Pkm

pyruvate kinase, muscle

chr11_+_120491840 3.480 ENSMUST00000026899.3
Slc25a10
solute carrier family 25 (mitochondrial carrier, dicarboxylate transporter), member 10
chr19_-_5912771 3.459 ENSMUST00000118623.1
Dpf2
D4, zinc and double PHD fingers family 2
chr8_-_84893887 3.273 ENSMUST00000003907.7
ENSMUST00000182458.1
ENSMUST00000109745.1
ENSMUST00000142748.1
Gcdh



glutaryl-Coenzyme A dehydrogenase



chr17_+_44188564 3.236 ENSMUST00000024755.5
Clic5
chloride intracellular channel 5
chr5_-_3473178 3.225 ENSMUST00000168422.1
Gm17590
predicted gene, 17590
chr10_-_107123585 3.173 ENSMUST00000165067.1
ENSMUST00000044668.4
Acss3

acyl-CoA synthetase short-chain family member 3

chr15_-_101054399 3.142 ENSMUST00000178140.1
Fignl2
fidgetin-like 2
chr11_+_53770458 3.100 ENSMUST00000138913.1
ENSMUST00000123376.1
ENSMUST00000019043.6
ENSMUST00000133291.1
Irf1



interferon regulatory factor 1



chr1_+_131867224 3.098 ENSMUST00000112386.1
ENSMUST00000027693.7
Rab7l1

RAB7, member RAS oncogene family-like 1

chr12_+_113098199 3.075 ENSMUST00000009099.6
ENSMUST00000109723.1
ENSMUST00000109726.1
ENSMUST00000109727.2
ENSMUST00000069690.4
Mta1




metastasis associated 1




chr2_-_5862923 3.030 ENSMUST00000071016.2
Gm13199
predicted gene 13199
chr7_-_65370908 2.982 ENSMUST00000032729.6
Tjp1
tight junction protein 1
chr18_+_59062282 2.968 ENSMUST00000165666.2
A730017C20Rik
RIKEN cDNA A730017C20 gene
chr2_-_170427828 2.944 ENSMUST00000013667.2
ENSMUST00000109152.2
ENSMUST00000068137.4
Bcas1


breast carcinoma amplified sequence 1


chr16_-_23225334 2.911 ENSMUST00000055369.4
BC106179
cDNA sequence BC106179
chr1_+_52630692 2.855 ENSMUST00000165859.1
Tmem194b
transmembrane protein 194B
chr18_+_59062462 2.845 ENSMUST00000058633.2
ENSMUST00000175897.1
ENSMUST00000118510.1
ENSMUST00000175830.1
A730017C20Rik



RIKEN cDNA A730017C20 gene



chrX_-_72274747 2.842 ENSMUST00000064780.3
Gabre
gamma-aminobutyric acid (GABA) A receptor, subunit epsilon
chr17_-_25844514 2.823 ENSMUST00000176709.1
Rhot2
ras homolog gene family, member T2
chr4_-_151044564 2.779 ENSMUST00000103204.4
Per3
period circadian clock 3
chr1_-_156036473 2.756 ENSMUST00000097527.3
ENSMUST00000027738.7
Tor1aip1

torsin A interacting protein 1

chr5_+_137629169 2.695 ENSMUST00000176667.1
Lrch4
leucine-rich repeats and calponin homology (CH) domain containing 4
chr9_+_110880192 2.695 ENSMUST00000130386.1
Als2cl
ALS2 C-terminal like
chr11_+_99864476 2.689 ENSMUST00000092694.3
Gm11559
predicted gene 11559
chr6_-_86669136 2.676 ENSMUST00000001184.7
Mxd1
MAX dimerization protein 1
chr11_+_102881204 2.662 ENSMUST00000021307.3
ENSMUST00000159834.1
Ccdc103

coiled-coil domain containing 103

chr2_-_153529941 2.633 ENSMUST00000035346.7
8430427H17Rik
RIKEN cDNA 8430427H17 gene
chr18_+_56432116 2.619 ENSMUST00000070166.5
Gramd3
GRAM domain containing 3
chr12_-_17011727 2.581 ENSMUST00000095823.2
2410004P03Rik
RIKEN cDNA 2410004P03 gene
chr17_-_65951156 2.549 ENSMUST00000024906.4
Twsg1
twisted gastrulation homolog 1 (Drosophila)
chr17_+_28272191 2.546 ENSMUST00000169040.1
Ppard
peroxisome proliferator activator receptor delta
chr4_+_98923845 2.542 ENSMUST00000091358.4
Usp1
ubiquitin specific peptidase 1
chr17_-_55712571 2.502 ENSMUST00000086876.5
Pot1b
protection of telomeres 1B
chr12_+_3572379 2.491 ENSMUST00000173199.1
ENSMUST00000164578.2
ENSMUST00000174479.1
ENSMUST00000173240.1
ENSMUST00000174663.1
ENSMUST00000173736.1
Dtnb





dystrobrevin, beta





chr16_-_85901118 2.473 ENSMUST00000023611.5
Adamts5
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2)
chr4_+_125066672 2.379 ENSMUST00000052183.6
Snip1
Smad nuclear interacting protein 1
chr13_+_22043189 2.347 ENSMUST00000110452.1
Hist1h2bj
histone cluster 1, H2bj
chr1_+_88227005 2.286 ENSMUST00000061013.6
ENSMUST00000113130.1
Mroh2a

maestro heat-like repeat family member 2A

chr9_-_13245741 2.253 ENSMUST00000110582.2
Jrkl
jerky homolog-like (mouse)
chr1_+_160195215 2.229 ENSMUST00000135680.1
ENSMUST00000097193.2
Mrps14

mitochondrial ribosomal protein S14

chr19_-_8880883 2.204 ENSMUST00000096253.5
AI462493
expressed sequence AI462493
chr13_-_74482943 2.119 ENSMUST00000074369.6
Zfp825
zinc finger protein 825
chr4_+_111719975 2.111 ENSMUST00000038868.7
ENSMUST00000070513.6
ENSMUST00000153746.1
Spata6


spermatogenesis associated 6


chr5_-_137611429 2.091 ENSMUST00000031731.7
Pcolce
procollagen C-endopeptidase enhancer protein
chr7_-_133782721 2.077 ENSMUST00000063669.1
Dhx32
DEAH (Asp-Glu-Ala-His) box polypeptide 32
chr18_+_24205303 2.031 ENSMUST00000000430.7
Galnt1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1
chr19_+_6364557 2.001 ENSMUST00000155973.1
Sf1
splicing factor 1
chr15_-_78305603 1.992 ENSMUST00000096356.3
Csf2rb2
colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)
chr2_-_28583189 1.947 ENSMUST00000113889.2
Gtf3c5
general transcription factor IIIC, polypeptide 5
chr14_+_54883377 1.942 ENSMUST00000022806.3
ENSMUST00000172844.1
ENSMUST00000133397.2
ENSMUST00000134077.1
Bcl2l2


Gm20521
BCL2-like 2


predicted gene 20521
chr5_-_116288944 1.933 ENSMUST00000086483.3
Ccdc60
coiled-coil domain containing 60
chr13_-_22042949 1.925 ENSMUST00000091741.4
Hist1h2ag
histone cluster 1, H2ag
chr17_-_25081138 1.920 ENSMUST00000024984.6
Tmem204
transmembrane protein 204
chr6_+_146888481 1.913 ENSMUST00000016631.7
ENSMUST00000111623.2
Ppfibp1

PTPRF interacting protein, binding protein 1 (liprin beta 1)

chr8_-_70700070 1.851 ENSMUST00000116172.1
Gm11175
predicted gene 11175
chr5_-_137611372 1.845 ENSMUST00000054564.6
Pcolce
procollagen C-endopeptidase enhancer protein
chr3_-_133091764 1.804 ENSMUST00000029651.4
Gstcd
glutathione S-transferase, C-terminal domain containing
chr6_-_85765744 1.780 ENSMUST00000050780.7
Cml3
camello-like 3
chr5_-_31241215 1.778 ENSMUST00000068997.3
Gm9970
predicted gene 9970
chr3_+_107036156 1.663 ENSMUST00000052718.3
Kcna3
potassium voltage-gated channel, shaker-related subfamily, member 3
chr4_-_135494615 1.639 ENSMUST00000102549.3
Nipal3
NIPA-like domain containing 3
chr19_-_5388656 1.636 ENSMUST00000044207.4
Sart1
squamous cell carcinoma antigen recognized by T cells 1
chr18_+_24205722 1.632 ENSMUST00000170243.1
Galnt1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1
chr18_+_48045329 1.614 ENSMUST00000076155.4
Gm5506
predicted gene 5506
chr6_-_53820764 1.594 ENSMUST00000127748.2
Tril
TLR4 interactor with leucine-rich repeats
chr11_-_115187827 1.581 ENSMUST00000103041.1
Nat9
N-acetyltransferase 9 (GCN5-related, putative)
chr3_-_133092029 1.567 ENSMUST00000080583.5
Gstcd
glutathione S-transferase, C-terminal domain containing
chr16_+_23226014 1.565 ENSMUST00000178797.1
St6gal1
beta galactoside alpha 2,6 sialyltransferase 1
chr19_+_6335093 1.547 ENSMUST00000078137.5
Men1
multiple endocrine neoplasia 1
chr6_-_124779686 1.534 ENSMUST00000147669.1
ENSMUST00000128697.1
ENSMUST00000032218.3
ENSMUST00000112475.2
Lrrc23



leucine rich repeat containing 23



chr11_-_119355484 1.519 ENSMUST00000100172.2
ENSMUST00000005173.4
Sgsh

N-sulfoglucosamine sulfohydrolase (sulfamidase)

chr3_-_95687846 1.515 ENSMUST00000015994.3
ENSMUST00000148854.1
ENSMUST00000117782.1
Adamtsl4


ADAMTS-like 4


chr2_+_150909565 1.508 ENSMUST00000028948.4
Gins1
GINS complex subunit 1 (Psf1 homolog)
chr16_+_20696175 1.480 ENSMUST00000128273.1
Fam131a
family with sequence similarity 131, member A
chr9_+_110880157 1.478 ENSMUST00000084926.2
Als2cl
ALS2 C-terminal like
chr8_-_119558718 1.458 ENSMUST00000081381.4
ENSMUST00000098362.3
Mbtps1

membrane-bound transcription factor peptidase, site 1

chr11_+_68968107 1.450 ENSMUST00000102606.3
ENSMUST00000018884.5
Slc25a35

solute carrier family 25, member 35

chr1_-_165194310 1.420 ENSMUST00000043338.4
Sft2d2
SFT2 domain containing 2
chr9_-_22117123 1.402 ENSMUST00000013966.6
Elof1
elongation factor 1 homolog (ELF1, S. cerevisiae)
chr15_+_80948484 1.399 ENSMUST00000023043.2
ENSMUST00000168756.1
ENSMUST00000164806.1
Adsl


adenylosuccinate lyase


chr3_+_133091840 1.373 ENSMUST00000029650.8
Ints12
integrator complex subunit 12
chr3_-_122984404 1.360 ENSMUST00000090379.2
Usp53
ubiquitin specific peptidase 53
chr4_-_135494499 1.346 ENSMUST00000105856.2
Nipal3
NIPA-like domain containing 3
chr9_+_6168638 1.318 ENSMUST00000058692.7
Pdgfd
platelet-derived growth factor, D polypeptide
chr4_+_98923908 1.282 ENSMUST00000169053.1
Usp1
ubiquitin specific peptidase 1
chr19_+_37436707 1.279 ENSMUST00000128184.1
Hhex
hematopoietically expressed homeobox
chr19_+_6334979 1.265 ENSMUST00000113504.3
ENSMUST00000113502.3
ENSMUST00000079327.5
ENSMUST00000056391.8
ENSMUST00000113501.1
ENSMUST00000113500.1
ENSMUST00000166909.1
Men1






multiple endocrine neoplasia 1






chr2_-_62646146 1.265 ENSMUST00000112459.3
ENSMUST00000028259.5
Ifih1

interferon induced with helicase C domain 1

chr4_+_111720187 1.265 ENSMUST00000084354.3
Spata6
spermatogenesis associated 6
chr10_+_116301374 1.249 ENSMUST00000092167.5
Ptprb
protein tyrosine phosphatase, receptor type, B
chr2_+_112265809 1.240 ENSMUST00000110991.2
Slc12a6
solute carrier family 12, member 6
chr15_-_76014318 1.212 ENSMUST00000060807.5
Fam83h
family with sequence similarity 83, member H
chr7_-_139683797 1.206 ENSMUST00000129990.1
ENSMUST00000130453.1
9330101J02Rik

RIKEN cDNA 9330101J02 gene

chr2_-_39005574 1.196 ENSMUST00000080861.5
Rpl35
ribosomal protein L35
chr11_+_101070012 1.190 ENSMUST00000001802.9
Naglu
alpha-N-acetylglucosaminidase (Sanfilippo disease IIIB)
chr1_+_164503306 1.185 ENSMUST00000181831.1
Gm26685
predicted gene, 26685
chr5_+_118169712 1.123 ENSMUST00000054836.6
Hrk
harakiri, BCL2 interacting protein (contains only BH3 domain)
chr11_-_102880981 1.081 ENSMUST00000107060.1
Eftud2
elongation factor Tu GTP binding domain containing 2
chr12_-_40134175 1.045 ENSMUST00000078481.7
ENSMUST00000002640.5
Scin

scinderin

chr15_-_98004634 1.031 ENSMUST00000131560.1
ENSMUST00000088355.5
Col2a1

collagen, type II, alpha 1

chr3_-_67375163 1.030 ENSMUST00000166353.1
Gm17402
predicted gene, 17402
chr10_-_81266906 1.016 ENSMUST00000046114.4
Mrpl54
mitochondrial ribosomal protein L54
chr3_-_108840477 1.008 ENSMUST00000106596.3
ENSMUST00000102621.4
Stxbp3a

syntaxin binding protein 3A

chr17_-_35115428 0.993 ENSMUST00000172854.1
ENSMUST00000062657.4
Ly6g5b

lymphocyte antigen 6 complex, locus G5B

chr16_-_17561240 0.993 ENSMUST00000065125.5
ENSMUST00000100123.3
ENSMUST00000023442.6
4930451C15Rik


RIKEN cDNA 4930451C15 gene


chr19_-_21652779 0.975 ENSMUST00000179768.1
ENSMUST00000178523.1
ENSMUST00000038830.3
1110059E24Rik


RIKEN cDNA 1110059E24 gene


chr7_-_19399859 0.952 ENSMUST00000047170.3
ENSMUST00000108459.2
Klc3

kinesin light chain 3

chr11_+_101425068 0.942 ENSMUST00000040561.5
Rundc1
RUN domain containing 1
chr5_-_41844168 0.933 ENSMUST00000050556.7
Bod1l
biorientation of chromosomes in cell division 1-like
chr7_-_41393260 0.865 ENSMUST00000071804.7
AI987944
expressed sequence AI987944
chr4_+_109676568 0.852 ENSMUST00000102724.4
Faf1
Fas-associated factor 1
chr1_+_75521521 0.850 ENSMUST00000027414.9
ENSMUST00000113553.1
Stk11ip

serine/threonine kinase 11 interacting protein

chr11_-_102880925 0.805 ENSMUST00000021306.7
Eftud2
elongation factor Tu GTP binding domain containing 2
chr9_-_50739365 0.761 ENSMUST00000117093.1
ENSMUST00000121634.1
Dixdc1

DIX domain containing 1

chr13_-_76098606 0.751 ENSMUST00000120573.1
Arsk
arylsulfatase K
chr5_+_136116631 0.740 ENSMUST00000111127.1
ENSMUST00000041366.7
ENSMUST00000111129.1
Polr2j


polymerase (RNA) II (DNA directed) polypeptide J


chr1_-_121332571 0.739 ENSMUST00000071064.6
Insig2
insulin induced gene 2
chr3_-_151749877 0.716 ENSMUST00000029671.7
Ifi44
interferon-induced protein 44
chr5_-_116288978 0.715 ENSMUST00000050178.6
Ccdc60
coiled-coil domain containing 60
chr5_-_138171248 0.707 ENSMUST00000153867.1
Mcm7
minichromosome maintenance deficient 7 (S. cerevisiae)
chr6_-_148831448 0.681 ENSMUST00000048418.7
Ipo8
importin 8
chr3_-_95315086 0.678 ENSMUST00000098867.3
Gm10691
predicted gene 10691

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
5.6 16.9 GO:0071579 regulation of zinc ion transport(GO:0071579)
5.5 16.6 GO:1904274 tricellular tight junction assembly(GO:1904274)
5.2 15.7 GO:0061349 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333) hypophysis morphogenesis(GO:0048850) cervix development(GO:0060067) planar cell polarity pathway involved in outflow tract morphogenesis(GO:0061347) planar cell polarity pathway involved in ventricular septum morphogenesis(GO:0061348) planar cell polarity pathway involved in cardiac right atrium morphogenesis(GO:0061349) planar cell polarity pathway involved in cardiac muscle tissue morphogenesis(GO:0061350) planar cell polarity pathway involved in pericardium morphogenesis(GO:0061354)
3.3 9.9 GO:0051464 positive regulation of cortisol secretion(GO:0051464)
2.9 11.6 GO:0006982 response to lipid hydroperoxide(GO:0006982) cellular response to lipid hydroperoxide(GO:0071449)
2.9 8.6 GO:0042939 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
2.7 10.9 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
2.7 13.6 GO:0032901 positive regulation of neurotrophin production(GO:0032901)
2.6 7.8 GO:0071649 regulation of chemokine (C-C motif) ligand 5 production(GO:0071649)
2.5 9.8 GO:0038128 ERBB2 signaling pathway(GO:0038128)
2.2 11.0 GO:0048852 diencephalon morphogenesis(GO:0048852)
2.1 35.7 GO:0030953 astral microtubule organization(GO:0030953)
1.7 5.1 GO:0072034 renal vesicle induction(GO:0072034)
1.7 10.0 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
1.6 7.8 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
1.5 9.3 GO:0003383 apical constriction(GO:0003383)
1.5 13.7 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
1.5 4.4 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
1.2 4.8 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
1.1 14.3 GO:0035881 amacrine cell differentiation(GO:0035881)
1.0 3.1 GO:2000564 CD8-positive, alpha-beta T cell proliferation(GO:0035740) negative regulation of regulatory T cell differentiation(GO:0045590) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
1.0 3.1 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.9 6.4 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
0.9 9.0 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.9 12.3 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.9 3.5 GO:0015744 succinate transport(GO:0015744)
0.8 2.5 GO:2000562 negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.8 2.5 GO:0048239 negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.8 4.1 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.8 3.2 GO:0002024 diet induced thermogenesis(GO:0002024)
0.8 4.0 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.7 3.7 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.7 9.3 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.6 2.5 GO:0006776 vitamin A metabolic process(GO:0006776)
0.6 6.7 GO:0036159 outer dynein arm assembly(GO:0036158) inner dynein arm assembly(GO:0036159)
0.6 3.5 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.5 15.3 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.5 1.5 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.5 6.5 GO:0045199 maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.5 3.9 GO:0035372 protein localization to microtubule(GO:0035372)
0.5 5.4 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.5 1.4 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.4 1.3 GO:0035696 monocyte extravasation(GO:0035696) regulation of monocyte extravasation(GO:2000437)
0.4 1.6 GO:2000110 protein sialylation(GO:1990743) negative regulation of macrophage apoptotic process(GO:2000110)
0.4 6.5 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.4 2.8 GO:0002051 osteoblast fate commitment(GO:0002051)
0.3 3.8 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.3 1.9 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.3 1.3 GO:0061010 gall bladder development(GO:0061010)
0.3 1.3 GO:0035547 interferon-beta secretion(GO:0035546) regulation of interferon-beta secretion(GO:0035547) positive regulation of interferon-beta secretion(GO:0035549)
0.3 2.8 GO:0071763 nuclear membrane organization(GO:0071763)
0.3 1.6 GO:0045583 regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585)
0.3 3.0 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.3 5.3 GO:0060009 Sertoli cell development(GO:0060009)
0.2 8.6 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.2 6.5 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.2 1.1 GO:0051365 cellular response to potassium ion starvation(GO:0051365)
0.2 4.2 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.2 3.3 GO:0035337 fatty-acyl-CoA metabolic process(GO:0035337)
0.2 1.5 GO:1902969 mitotic DNA replication(GO:1902969)
0.2 7.4 GO:0003016 respiratory system process(GO:0003016)
0.2 3.4 GO:0044458 motile cilium assembly(GO:0044458)
0.2 4.7 GO:0003009 skeletal muscle contraction(GO:0003009)
0.2 4.3 GO:0008340 determination of adult lifespan(GO:0008340)
0.2 1.2 GO:0035826 rubidium ion transport(GO:0035826) cellular hypotonic response(GO:0071476)
0.2 3.0 GO:0015693 magnesium ion transport(GO:0015693)
0.2 5.8 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.2 2.0 GO:0030238 male sex determination(GO:0030238)
0.1 1.0 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.1 0.9 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.1 11.0 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 13.2 GO:0051592 response to calcium ion(GO:0051592)
0.1 1.2 GO:0046548 retinal rod cell development(GO:0046548)
0.1 2.3 GO:0006334 nucleosome assembly(GO:0006334)
0.1 0.8 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.1 2.8 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 3.1 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.1 0.6 GO:0051013 microtubule severing(GO:0051013)
0.1 1.0 GO:0060174 limb bud formation(GO:0060174)
0.1 1.2 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.1 1.2 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.1 1.4 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 1.9 GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030947)
0.1 1.6 GO:0034142 toll-like receptor 4 signaling pathway(GO:0034142)
0.1 0.4 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.1 4.4 GO:0010507 negative regulation of autophagy(GO:0010507)
0.1 4.6 GO:0030032 lamellipodium assembly(GO:0030032)
0.1 1.2 GO:0016180 snRNA processing(GO:0016180)
0.1 0.5 GO:0006560 proline metabolic process(GO:0006560)
0.0 1.9 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 3.8 GO:0007569 cell aging(GO:0007569)
0.0 0.3 GO:1990504 dense core granule exocytosis(GO:1990504)
0.0 0.9 GO:0031297 replication fork processing(GO:0031297)
0.0 4.9 GO:0006342 chromatin silencing(GO:0006342)
0.0 2.3 GO:0007032 endosome organization(GO:0007032)
0.0 1.4 GO:0010996 response to auditory stimulus(GO:0010996)
0.0 3.2 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 3.5 GO:0006400 tRNA modification(GO:0006400)
0.0 1.2 GO:0044380 protein localization to cytoskeleton(GO:0044380)
0.0 0.5 GO:0090201 negative regulation of release of cytochrome c from mitochondria(GO:0090201)
0.0 0.1 GO:0002159 desmosome assembly(GO:0002159) adherens junction maintenance(GO:0034334) intermediate filament bundle assembly(GO:0045110) maintenance of organ identity(GO:0048496)
0.0 1.7 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.0 0.2 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 2.4 GO:1903749 positive regulation of establishment of protein localization to mitochondrion(GO:1903749) positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 8.8 GO:0000398 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0 1.5 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 0.5 GO:0043276 anoikis(GO:0043276)
0.0 2.5 GO:0042742 defense response to bacterium(GO:0042742)
0.0 0.1 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.0 3.6 GO:0006006 glucose metabolic process(GO:0006006)
0.0 0.6 GO:0007179 transforming growth factor beta receptor signaling pathway(GO:0007179) cellular response to transforming growth factor beta stimulus(GO:0071560)
0.0 0.9 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.2 GO:0042407 cristae formation(GO:0042407)
0.0 1.9 GO:0008380 RNA splicing(GO:0008380)
0.0 0.5 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
0.0 0.2 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 2.7 GO:0051260 protein homooligomerization(GO:0051260)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 16.6 GO:0061689 tricellular tight junction(GO:0061689)
2.7 13.7 GO:0033010 paranodal junction(GO:0033010)
1.2 9.3 GO:0033269 internode region of axon(GO:0033269)
1.1 9.1 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.8 4.7 GO:0097513 myosin II filament(GO:0097513)
0.8 8.6 GO:0032426 stereocilium tip(GO:0032426)
0.5 1.5 GO:0000811 GINS complex(GO:0000811)
0.4 3.0 GO:0046581 intercellular canaliculus(GO:0046581)
0.3 11.0 GO:0060077 inhibitory synapse(GO:0060077)
0.3 1.6 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.3 2.5 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.2 1.9 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.2 19.4 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.2 6.5 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.2 4.0 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.2 1.9 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.2 6.9 GO:0090544 BAF-type complex(GO:0090544)
0.2 6.6 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.2 1.6 GO:0000138 Golgi trans cisterna(GO:0000138)
0.2 13.6 GO:0005776 autophagosome(GO:0005776)
0.1 1.2 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 10.6 GO:0000786 nucleosome(GO:0000786)
0.1 21.3 GO:0055037 recycling endosome(GO:0055037)
0.1 27.4 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.1 6.9 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 3.5 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.1 3.1 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 4.4 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.1 7.8 GO:0005871 kinesin complex(GO:0005871)
0.1 4.3 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.1 1.9 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 1.2 GO:0045095 keratin filament(GO:0045095)
0.1 3.2 GO:0032420 stereocilium(GO:0032420)
0.1 0.9 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1 4.0 GO:0005929 cilium(GO:0005929)
0.1 1.5 GO:0005614 interstitial matrix(GO:0005614)
0.1 4.2 GO:0008180 COP9 signalosome(GO:0008180)
0.1 8.2 GO:0016605 PML body(GO:0016605)
0.1 1.0 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 4.6 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.1 1.2 GO:0032039 integrator complex(GO:0032039)
0.1 3.0 GO:0030667 secretory granule membrane(GO:0030667)
0.1 2.8 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 5.5 GO:0032587 ruffle membrane(GO:0032587)
0.1 35.5 GO:0005813 centrosome(GO:0005813)
0.1 5.3 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 2.2 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 8.4 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.1 0.2 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 4.2 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 1.2 GO:0043235 receptor complex(GO:0043235)
0.0 10.3 GO:0005681 spliceosomal complex(GO:0005681)
0.0 4.7 GO:0031514 motile cilium(GO:0031514)
0.0 0.7 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 1.4 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 1.6 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.5 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 3.5 GO:0061695 transferase complex, transferring phosphorus-containing groups(GO:0061695)
0.0 8.1 GO:0000790 nuclear chromatin(GO:0000790)
0.0 11.6 GO:0005925 focal adhesion(GO:0005925)
0.0 20.9 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 0.7 GO:0012505 endomembrane system(GO:0012505)
0.0 1.5 GO:0005795 Golgi stack(GO:0005795)
0.0 4.6 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.4 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 1.0 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.1 GO:0030057 desmosome(GO:0030057)
0.0 1.2 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 4.1 GO:0031012 extracellular matrix(GO:0031012)
0.0 1.0 GO:0009897 external side of plasma membrane(GO:0009897)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
5.2 15.7 GO:0005110 frizzled-2 binding(GO:0005110)
2.5 9.9 GO:0004966 galanin receptor activity(GO:0004966)
2.3 9.1 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
1.7 13.6 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
1.6 7.8 GO:0050700 CARD domain binding(GO:0050700)
1.2 3.5 GO:0004743 pyruvate kinase activity(GO:0004743)
1.2 3.5 GO:0015140 malate transmembrane transporter activity(GO:0015140)
1.1 3.2 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.8 2.5 GO:0016501 prostacyclin receptor activity(GO:0016501)
0.8 14.4 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.7 16.4 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.7 3.4 GO:0032027 myosin light chain binding(GO:0032027)
0.7 4.0 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.7 8.0 GO:0036310 annealing helicase activity(GO:0036310)
0.7 8.6 GO:0017081 chloride channel regulator activity(GO:0017081)
0.6 9.1 GO:0003688 DNA replication origin binding(GO:0003688)
0.6 1.9 GO:0000992 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003) RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034)
0.6 11.7 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.6 16.9 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.5 22.4 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.5 3.6 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.5 2.0 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.5 9.4 GO:0035198 miRNA binding(GO:0035198)
0.5 11.6 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.5 2.8 GO:0000403 Y-form DNA binding(GO:0000403)
0.4 18.9 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.4 2.5 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.3 1.4 GO:0016842 amidine-lyase activity(GO:0016842)
0.3 4.7 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.3 1.6 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.3 1.2 GO:1990254 keratin filament binding(GO:1990254)
0.3 4.2 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.2 6.4 GO:0070064 proline-rich region binding(GO:0070064)
0.2 7.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.2 1.0 GO:0042289 MHC class II protein binding(GO:0042289)
0.2 9.3 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.2 3.3 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.2 0.5 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.2 1.2 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.2 2.8 GO:0004890 GABA-A receptor activity(GO:0004890)
0.2 3.0 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.2 1.5 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.2 0.5 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.1 2.0 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.1 10.5 GO:0008186 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.1 1.9 GO:0051400 BH domain binding(GO:0051400)
0.1 2.5 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.1 2.8 GO:0005521 lamin binding(GO:0005521)
0.1 1.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 6.2 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 3.1 GO:0016887 ATPase activity(GO:0016887)
0.1 1.2 GO:0015929 hexosaminidase activity(GO:0015929)
0.1 14.3 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.1 1.6 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.1 8.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 7.8 GO:0003777 microtubule motor activity(GO:0003777)
0.1 1.7 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 3.1 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1 61.1 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977)
0.1 0.6 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 0.7 GO:0001055 RNA polymerase II activity(GO:0001055)
0.1 0.5 GO:0071253 connexin binding(GO:0071253)
0.1 3.1 GO:0016504 peptidase activator activity(GO:0016504)
0.1 3.2 GO:0005254 chloride channel activity(GO:0005254)
0.1 5.5 GO:0005178 integrin binding(GO:0005178)
0.1 1.4 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.2 GO:0005244 voltage-gated ion channel activity(GO:0005244) voltage-gated channel activity(GO:0022832)
0.0 0.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 4.1 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.5 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.9 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 1.3 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 4.3 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.5 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.0 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 15.8 GO:0019904 protein domain specific binding(GO:0019904)
0.0 5.4 GO:0045296 cadherin binding(GO:0045296)
0.0 1.2 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.6 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 1.1 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.0 0.2 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 1.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 8.9 GO:0016491 oxidoreductase activity(GO:0016491)
0.0 6.0 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.6 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 13.7 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.8 34.4 PID_AURORA_A_PATHWAY Aurora A signaling
0.7 14.0 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.6 28.0 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway
0.3 9.3 PID_PRL_SIGNALING_EVENTS_PATHWAY Signaling events mediated by PRL
0.2 9.0 PID_ATR_PATHWAY ATR signaling pathway
0.1 4.0 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.1 8.6 PID_TXA2PATHWAY Thromboxane A2 receptor signaling
0.1 3.0 PID_NEPHRIN_NEPH1_PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.1 3.8 PID_FANCONI_PATHWAY Fanconi anemia pathway
0.1 8.9 SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES Genes related to the insulin receptor pathway
0.1 3.1 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.1 7.5 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity
0.1 2.5 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 1.3 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 2.7 PID_TELOMERASE_PATHWAY Regulation of Telomerase
0.0 3.1 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.0 2.4 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 7.7 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.0 1.1 PID_ATF2_PATHWAY ATF-2 transcription factor network
0.0 1.3 NABA_COLLAGENS Genes encoding collagen proteins
0.0 0.5 PID_TRAIL_PATHWAY TRAIL signaling pathway
0.0 2.7 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.5 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.9 ST_FAS_SIGNALING_PATHWAY Fas Signaling Pathway
0.0 1.6 PID_P53_DOWNSTREAM_PATHWAY Direct p53 effectors
0.0 0.8 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.2 PID_NETRIN_PATHWAY Netrin-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 10.5 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.6 12.2 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.4 11.6 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.4 3.0 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.4 3.8 REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.4 10.4 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.3 9.3 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.2 15.7 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.2 6.5 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.2 3.2 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.2 1.6 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.2 13.7 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 4.7 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 1.5 REACTOME_ACTIVATION_OF_CHAPERONES_BY_ATF6_ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.1 3.7 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.1 1.4 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 0.8 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 7.6 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 2.8 REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1 0.5 REACTOME_FGFR4_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.1 1.9 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_2_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.1 1.5 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.1 0.7 REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 1.9 REACTOME_MRNA_SPLICING_MINOR_PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.5 REACTOME_NFKB_ACTIVATION_THROUGH_FADD_RIP1_PATHWAY_MEDIATED_BY_CASPASE_8_AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 2.2 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 1.7 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.6 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 1.0 REACTOME_KINESINS Genes involved in Kinesins
0.0 6.1 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 3.7 REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 2.0 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.0 0.2 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.5 REACTOME_MRNA_3_END_PROCESSING Genes involved in mRNA 3'-end processing