Motif ID: Scrt1

Z-value: 1.396


Transcription factors associated with Scrt1:

Gene SymbolEntrez IDGene Name
Scrt1 ENSMUSG00000048385.8 Scrt1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Scrt1mm10_v2_chr15_-_76521902_76522129-0.216.6e-02Click!


Activity profile for motif Scrt1.

activity profile for motif Scrt1


Sorted Z-values histogram for motif Scrt1

Sorted Z-values for motif Scrt1



Network of associatons between targets according to the STRING database.



First level regulatory network of Scrt1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_185454803 16.887 ENSMUST00000061093.6
Slc30a10
solute carrier family 30, member 10
chr14_+_28511344 15.677 ENSMUST00000112272.1
Wnt5a
wingless-related MMTV integration site 5A
chr5_-_114273702 14.296 ENSMUST00000144050.1
ENSMUST00000044790.5
Foxn4

forkhead box N4

chr5_+_33658567 13.891 ENSMUST00000114426.3
Tacc3
transforming, acidic coiled-coil containing protein 3
chr9_+_91368811 13.801 ENSMUST00000173054.1
Zic4
zinc finger protein of the cerebellum 4
chr9_-_27155418 13.715 ENSMUST00000167074.1
ENSMUST00000034472.8
Jam3

junction adhesion molecule 3

chr11_-_100355383 13.568 ENSMUST00000146878.2
Hap1
huntingtin-associated protein 1
chr9_+_91368970 13.130 ENSMUST00000172646.1
Zic4
zinc finger protein of the cerebellum 4
chr6_+_128375456 12.684 ENSMUST00000100926.2
4933413G19Rik
RIKEN cDNA 4933413G19 gene
chr6_+_138140521 11.603 ENSMUST00000120939.1
ENSMUST00000120302.1
Mgst1

microsomal glutathione S-transferase 1

chr5_+_33658550 11.301 ENSMUST00000152847.1
Tacc3
transforming, acidic coiled-coil containing protein 3
chr3_+_34649987 11.040 ENSMUST00000099151.2
Sox2
SRY-box containing gene 2
chr11_-_101466222 10.858 ENSMUST00000040430.7
Vat1
vesicle amine transport protein 1 homolog (T californica)
chr5_+_33658123 10.501 ENSMUST00000074849.6
ENSMUST00000079534.4
Tacc3

transforming, acidic coiled-coil containing protein 3

chr18_-_82406777 9.874 ENSMUST00000065224.6
Galr1
galanin receptor 1
chr4_-_19570073 9.814 ENSMUST00000029885.4
Cpne3
copine III
chr10_+_26229707 9.541 ENSMUST00000060716.5
ENSMUST00000164660.1
Samd3

sterile alpha motif domain containing 3

chr7_-_44815658 9.318 ENSMUST00000107893.1
Atf5
activating transcription factor 5
chr8_+_127064107 9.277 ENSMUST00000162536.1
ENSMUST00000026921.6
ENSMUST00000162665.1
ENSMUST00000160766.1
ENSMUST00000162602.1
ENSMUST00000162531.1
ENSMUST00000160581.1
ENSMUST00000161355.1
ENSMUST00000159537.1
Pard3








par-3 (partitioning defective 3) homolog (C. elegans)








chr6_-_88898664 9.100 ENSMUST00000058011.6
Mcm2
minichromosome maintenance deficient 2 mitotin (S. cerevisiae)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 117 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.1 35.7 GO:0030953 astral microtubule organization(GO:0030953)
5.6 16.9 GO:0071579 regulation of zinc ion transport(GO:0071579)
5.5 16.6 GO:1904274 tricellular tight junction assembly(GO:1904274)
5.2 15.7 GO:0061349 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333) hypophysis morphogenesis(GO:0048850) cervix development(GO:0060067) planar cell polarity pathway involved in outflow tract morphogenesis(GO:0061347) planar cell polarity pathway involved in ventricular septum morphogenesis(GO:0061348) planar cell polarity pathway involved in cardiac right atrium morphogenesis(GO:0061349) planar cell polarity pathway involved in cardiac muscle tissue morphogenesis(GO:0061350) planar cell polarity pathway involved in pericardium morphogenesis(GO:0061354)
0.5 15.3 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
1.1 14.3 GO:0035881 amacrine cell differentiation(GO:0035881)
1.5 13.7 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
2.7 13.6 GO:0032901 positive regulation of neurotrophin production(GO:0032901)
0.1 13.2 GO:0051592 response to calcium ion(GO:0051592)
0.9 12.3 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
2.9 11.6 GO:0006982 response to lipid hydroperoxide(GO:0006982) cellular response to lipid hydroperoxide(GO:0071449)
2.2 11.0 GO:0048852 diencephalon morphogenesis(GO:0048852)
0.1 11.0 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
2.7 10.9 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
1.7 10.0 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
3.3 9.9 GO:0051464 positive regulation of cortisol secretion(GO:0051464)
2.5 9.8 GO:0038128 ERBB2 signaling pathway(GO:0038128)
1.5 9.3 GO:0003383 apical constriction(GO:0003383)
0.7 9.3 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.9 9.0 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 71 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 35.5 GO:0005813 centrosome(GO:0005813)
0.1 27.4 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.1 21.3 GO:0055037 recycling endosome(GO:0055037)
0.0 20.9 GO:0005887 integral component of plasma membrane(GO:0005887)
0.2 19.4 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
2.8 16.6 GO:0061689 tricellular tight junction(GO:0061689)
2.7 13.7 GO:0033010 paranodal junction(GO:0033010)
0.2 13.6 GO:0005776 autophagosome(GO:0005776)
0.0 11.6 GO:0005925 focal adhesion(GO:0005925)
0.3 11.0 GO:0060077 inhibitory synapse(GO:0060077)
0.1 10.6 GO:0000786 nucleosome(GO:0000786)
0.0 10.3 GO:0005681 spliceosomal complex(GO:0005681)
1.2 9.3 GO:0033269 internode region of axon(GO:0033269)
1.1 9.1 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.8 8.6 GO:0032426 stereocilium tip(GO:0032426)
0.1 8.4 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.1 8.2 GO:0016605 PML body(GO:0016605)
0.0 8.1 GO:0000790 nuclear chromatin(GO:0000790)
0.1 7.8 GO:0005871 kinesin complex(GO:0005871)
0.2 6.9 GO:0090544 BAF-type complex(GO:0090544)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 85 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 61.1 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977)
0.5 22.4 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.4 18.9 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.6 16.9 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.7 16.4 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 15.8 GO:0019904 protein domain specific binding(GO:0019904)
5.2 15.7 GO:0005110 frizzled-2 binding(GO:0005110)
0.8 14.4 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.1 14.3 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
1.7 13.6 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.6 11.7 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.5 11.6 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 10.5 GO:0008186 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
2.5 9.9 GO:0004966 galanin receptor activity(GO:0004966)
0.5 9.4 GO:0035198 miRNA binding(GO:0035198)
0.2 9.3 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
2.3 9.1 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.6 9.1 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 8.9 GO:0016491 oxidoreductase activity(GO:0016491)
0.7 8.6 GO:0017081 chloride channel regulator activity(GO:0017081)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 28 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 34.4 PID_AURORA_A_PATHWAY Aurora A signaling
0.6 28.0 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway
0.7 14.0 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
1.0 13.7 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.3 9.3 PID_PRL_SIGNALING_EVENTS_PATHWAY Signaling events mediated by PRL
0.2 9.0 PID_ATR_PATHWAY ATR signaling pathway
0.1 8.9 SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES Genes related to the insulin receptor pathway
0.1 8.6 PID_TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 7.7 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.1 7.5 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity
0.1 4.0 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.1 3.8 PID_FANCONI_PATHWAY Fanconi anemia pathway
0.1 3.1 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.0 3.1 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.1 3.0 PID_NEPHRIN_NEPH1_PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 2.7 PID_TELOMERASE_PATHWAY Regulation of Telomerase
0.0 2.7 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 2.5 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 2.4 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 1.6 PID_P53_DOWNSTREAM_PATHWAY Direct p53 effectors

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 34 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 15.7 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.2 13.7 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.6 12.2 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.4 11.6 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.7 10.5 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.4 10.4 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.3 9.3 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.1 7.6 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.2 6.5 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.0 6.1 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.1 4.7 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.4 3.8 REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.1 3.7 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.0 3.7 REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.2 3.2 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.4 3.0 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 2.8 REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 2.2 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 2.0 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.1 1.9 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_2_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter