Motif ID: Scrt2

Z-value: 1.117


Transcription factors associated with Scrt2:

Gene SymbolEntrez IDGene Name
Scrt2 ENSMUSG00000060257.2 Scrt2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Scrt2mm10_v2_chr2_+_152081529_152081624-0.689.4e-12Click!


Activity profile for motif Scrt2.

activity profile for motif Scrt2


Sorted Z-values histogram for motif Scrt2

Sorted Z-values for motif Scrt2



Network of associatons between targets according to the STRING database.



First level regulatory network of Scrt2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_+_111066154 21.096 ENSMUST00000042970.2
 Kcnj2
potassium inwardly-rectifying channel, subfamily J, member 2
chr3_-_53657339 17.169 ENSMUST00000091137.4
 Frem2
Fras1 related extracellular matrix protein 2
chr18_-_58209926 11.989 ENSMUST00000025497.6
 Fbn2
fibrillin 2
chr11_-_55419898 11.636 ENSMUST00000108858.1
ENSMUST00000141530.1
 Sparc

secreted acidic cysteine rich glycoprotein

chr15_-_71727815 11.512 ENSMUST00000022953.8
 Fam135b
family with sequence similarity 135, member B
chr7_+_126847908 11.240 ENSMUST00000147257.1
ENSMUST00000139174.1
 Doc2a

double C2, alpha

chr8_+_76902277 10.869 ENSMUST00000109912.1
ENSMUST00000128862.1
ENSMUST00000109911.1
 Nr3c2


nuclear receptor subfamily 3, group C, member 2


chr5_+_118169712 10.505 ENSMUST00000054836.6
 Hrk
harakiri, BCL2 interacting protein (contains only BH3 domain)
chr8_-_71537402 10.320 ENSMUST00000051672.7
 Bst2
bone marrow stromal cell antigen 2
chr9_+_45370185 10.142 ENSMUST00000085939.6
 Fxyd6
FXYD domain-containing ion transport regulator 6
chr12_-_40037387 9.727 ENSMUST00000146905.1
 Arl4a
ADP-ribosylation factor-like 4A
chr17_-_25570678 9.381 ENSMUST00000025003.3
ENSMUST00000173447.1
 Sox8

SRY-box containing gene 8

chr12_-_4592927 8.120 ENSMUST00000170816.1
 Gm3625
predicted gene 3625
chr11_+_103649498 8.065 ENSMUST00000057870.2
 Rprml
reprimo-like
chr19_-_57008187 7.261 ENSMUST00000118800.1
ENSMUST00000111584.2
ENSMUST00000122359.1
ENSMUST00000148049.1
 Afap1l2



actin filament associated protein 1-like 2



chr15_+_34306666 6.458 ENSMUST00000163455.2
ENSMUST00000022947.5
 Matn2

matrilin 2

chr4_-_119538769 6.227 ENSMUST00000079611.6
 AA415398
expressed sequence AA415398
chr15_+_6422240 5.809 ENSMUST00000163082.1
 Dab2
disabled 2, mitogen-responsive phosphoprotein
chrX_-_152769461 5.773 ENSMUST00000101141.2
ENSMUST00000062317.4
 Shroom2

shroom family member 2

chr16_+_42907563 5.542 ENSMUST00000151244.1
ENSMUST00000114694.2
 Zbtb20

zinc finger and BTB domain containing 20

chr7_+_81523531 5.501 ENSMUST00000181903.1
 2900076A07Rik
RIKEN cDNA 2900076A07 gene
chr10_-_79614012 5.453 ENSMUST00000059699.7
ENSMUST00000178228.1
 C2cd4c

C2 calcium-dependent domain containing 4C

chr11_+_53770458 5.247 ENSMUST00000138913.1
ENSMUST00000123376.1
ENSMUST00000019043.6
ENSMUST00000133291.1
 Irf1



interferon regulatory factor 1



chr7_+_81523555 5.006 ENSMUST00000180385.1
ENSMUST00000180879.1
ENSMUST00000181164.1
ENSMUST00000181264.1
 2900076A07Rik



RIKEN cDNA 2900076A07 gene



chr10_+_116177351 4.899 ENSMUST00000155606.1
ENSMUST00000128399.1
 Ptprr

protein tyrosine phosphatase, receptor type, R

chr6_-_23839137 4.874 ENSMUST00000166458.2
ENSMUST00000142913.2
ENSMUST00000115357.1
ENSMUST00000069074.7
ENSMUST00000115361.2
ENSMUST00000018122.7
ENSMUST00000115355.1
ENSMUST00000115356.2
 Cadps2







Ca2+-dependent activator protein for secretion 2







chrX_+_150547375 4.840 ENSMUST00000066337.6
ENSMUST00000112715.1
 Alas2

aminolevulinic acid synthase 2, erythroid

chr8_-_84147858 4.825 ENSMUST00000117424.2
ENSMUST00000040383.8
 Cc2d1a

coiled-coil and C2 domain containing 1A

chr12_+_4592992 4.586 ENSMUST00000062580.7
 Itsn2
intersectin 2
chr2_-_164443177 4.584 ENSMUST00000017153.3
 Sdc4
syndecan 4
chr2_-_60881360 4.159 ENSMUST00000164147.1
ENSMUST00000112509.1
 Rbms1

RNA binding motif, single stranded interacting protein 1

chr7_+_107370728 4.139 ENSMUST00000137663.1
ENSMUST00000073459.5
 Syt9

synaptotagmin IX

chr9_+_94669876 4.102 ENSMUST00000033463.9
 Slc9a9
solute carrier family 9 (sodium/hydrogen exchanger), member 9
chr3_-_89101907 4.046 ENSMUST00000081848.8
 Fdps
farnesyl diphosphate synthetase
chrX_+_153139941 3.829 ENSMUST00000039720.4
ENSMUST00000144175.2
 Rragb

Ras-related GTP binding B

chr18_-_82406777 3.686 ENSMUST00000065224.6
 Galr1
galanin receptor 1
chrX_-_101085352 3.683 ENSMUST00000101362.1
ENSMUST00000073927.4
 Slc7a3

solute carrier family 7 (cationic amino acid transporter, y+ system), member 3

chr2_+_107290590 3.609 ENSMUST00000037012.2
 Kcna4
potassium voltage-gated channel, shaker-related subfamily, member 4
chr6_-_135168162 3.478 ENSMUST00000045855.7
 Hebp1
heme binding protein 1
chr19_+_26753588 3.371 ENSMUST00000177116.1
 Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr9_-_78108587 3.364 ENSMUST00000162625.1
ENSMUST00000159099.1
 Fbxo9

f-box protein 9

chr10_+_56377300 3.208 ENSMUST00000068581.7
 Gja1
gap junction protein, alpha 1
chr17_-_24533709 2.916 ENSMUST00000061764.7
 Rab26
RAB26, member RAS oncogene family
chr7_-_127946725 2.791 ENSMUST00000118755.1
ENSMUST00000094026.3
 Prss36

protease, serine, 36

chr6_-_53820764 2.767 ENSMUST00000127748.2
 Tril
TLR4 interactor with leucine-rich repeats
chr2_+_31950257 2.756 ENSMUST00000001920.7
 Aif1l
allograft inflammatory factor 1-like
chr10_-_116473418 2.730 ENSMUST00000087965.4
ENSMUST00000164271.1
 Kcnmb4

potassium large conductance calcium-activated channel, subfamily M, beta member 4

chr19_-_61228396 2.722 ENSMUST00000076046.6
 Csf2ra
colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
chr7_-_25250720 2.646 ENSMUST00000116343.2
ENSMUST00000045847.8
 Erf

Ets2 repressor factor

chr3_-_122984404 2.633 ENSMUST00000090379.2
 Usp53
ubiquitin specific peptidase 53
chr7_+_123377982 2.322 ENSMUST00000033025.5
 Lcmt1
leucine carboxyl methyltransferase 1
chr5_+_37245792 2.283 ENSMUST00000031004.7
 Crmp1
collapsin response mediator protein 1
chrX_+_85048309 2.247 ENSMUST00000113991.1
ENSMUST00000113992.2
 Dmd

dystrophin, muscular dystrophy

chr3_-_57301919 2.176 ENSMUST00000029376.8
 Tm4sf1
transmembrane 4 superfamily member 1
chr5_-_137611372 2.165 ENSMUST00000054564.6
 Pcolce
procollagen C-endopeptidase enhancer protein
chr3_+_130180882 2.138 ENSMUST00000106353.1
ENSMUST00000080335.4
 Col25a1

collagen, type XXV, alpha 1

chr3_-_95315086 2.065 ENSMUST00000098867.3
 Gm10691
predicted gene 10691
chr1_-_79440039 2.063 ENSMUST00000049972.4
 Scg2
secretogranin II
chr4_+_15265798 2.001 ENSMUST00000062684.8
 Tmem64
transmembrane protein 64
chr13_+_97241096 1.984 ENSMUST00000041623.7
 Enc1
ectodermal-neural cortex 1
chr5_+_66676098 1.893 ENSMUST00000031131.9
 Uchl1
ubiquitin carboxy-terminal hydrolase L1
chr4_-_129189512 1.891 ENSMUST00000117965.1
ENSMUST00000106061.2
ENSMUST00000072431.6
 S100pbp


S100P binding protein


chr5_-_137611429 1.854 ENSMUST00000031731.7
 Pcolce
procollagen C-endopeptidase enhancer protein
chr3_-_108840477 1.749 ENSMUST00000106596.3
ENSMUST00000102621.4
 Stxbp3a

syntaxin binding protein 3A

chr4_-_129189646 1.589 ENSMUST00000106059.1
 S100pbp
S100P binding protein
chr13_+_21945084 1.546 ENSMUST00000176511.1
ENSMUST00000102978.1
ENSMUST00000152258.2
 Zfp184


zinc finger protein 184 (Kruppel-like)


chr4_+_129189760 1.532 ENSMUST00000106054.2
ENSMUST00000001365.2
 Yars

tyrosyl-tRNA synthetase

chr5_-_123684289 1.467 ENSMUST00000111564.1
ENSMUST00000063905.5
 Clip1

CAP-GLY domain containing linker protein 1

chr11_+_101070012 1.432 ENSMUST00000001802.9
 Naglu
alpha-N-acetylglucosaminidase (Sanfilippo disease IIIB)
chr18_-_3281036 1.373 ENSMUST00000049942.6
ENSMUST00000139537.1
ENSMUST00000124747.1
 Crem


cAMP responsive element modulator


chr4_-_45084538 1.353 ENSMUST00000052236.6
 Fbxo10
F-box protein 10
chr2_-_148732457 1.353 ENSMUST00000028926.6
 Napb
N-ethylmaleimide sensitive fusion protein attachment protein beta
chr16_-_92466081 1.285 ENSMUST00000060005.8
 Rcan1
regulator of calcineurin 1
chr4_-_129189600 1.264 ENSMUST00000117497.1
ENSMUST00000117350.1
 S100pbp

S100P binding protein

chrX_-_36645359 1.235 ENSMUST00000051906.6
 Akap17b
A kinase (PRKA) anchor protein 17B
chr3_+_81036360 1.227 ENSMUST00000029652.3
 Pdgfc
platelet-derived growth factor, C polypeptide
chr17_+_44188564 1.062 ENSMUST00000024755.5
 Clic5
chloride intracellular channel 5
chr5_-_31241215 1.061 ENSMUST00000068997.3
 Gm9970
predicted gene 9970
chr5_-_138171813 1.050 ENSMUST00000155902.1
ENSMUST00000148879.1
 Mcm7

minichromosome maintenance deficient 7 (S. cerevisiae)

chr13_+_83732438 0.972 ENSMUST00000182701.1
 C130071C03Rik
RIKEN cDNA C130071C03 gene
chr7_-_45830776 0.944 ENSMUST00000107723.2
ENSMUST00000131384.1
 Grwd1

glutamate-rich WD repeat containing 1

chr2_-_32260138 0.936 ENSMUST00000002625.8
 Uck1
uridine-cytidine kinase 1
chr11_-_106612928 0.910 ENSMUST00000042780.7
 Tex2
testis expressed gene 2
chr2_+_91256813 0.898 ENSMUST00000144394.1
ENSMUST00000028694.5
ENSMUST00000168916.1
ENSMUST00000156919.1
 Pacsin3



protein kinase C and casein kinase substrate in neurons 3



chr16_+_3884629 0.889 ENSMUST00000176233.1
 Gm20695
predicted gene 20695
chr2_+_91257323 0.837 ENSMUST00000111349.2
ENSMUST00000131711.1
 Pacsin3

protein kinase C and casein kinase substrate in neurons 3

chr17_-_56183887 0.800 ENSMUST00000019723.7
 D17Wsu104e
DNA segment, Chr 17, Wayne State University 104, expressed
chr12_+_65036319 0.784 ENSMUST00000120580.1
 Prpf39
PRP39 pre-mRNA processing factor 39 homolog (yeast)
chr5_+_138171997 0.781 ENSMUST00000019662.4
ENSMUST00000151318.1
 Ap4m1

adaptor-related protein complex AP-4, mu 1

chr12_-_86884808 0.751 ENSMUST00000038422.6
 Irf2bpl
interferon regulatory factor 2 binding protein-like
chr16_+_17070127 0.735 ENSMUST00000115729.1
 Ypel1
yippee-like 1 (Drosophila)
chr2_-_66634952 0.581 ENSMUST00000100064.2
ENSMUST00000100063.2
 Scn9a

sodium channel, voltage-gated, type IX, alpha

chr13_+_109260481 0.515 ENSMUST00000153234.1
 Pde4d
phosphodiesterase 4D, cAMP specific
chr5_-_138171216 0.438 ENSMUST00000147920.1
 Mcm7
minichromosome maintenance deficient 7 (S. cerevisiae)
chr13_-_98206151 0.393 ENSMUST00000109426.1
 Arhgef28
Rho guanine nucleotide exchange factor (GEF) 28
chr5_-_138171248 0.267 ENSMUST00000153867.1
 Mcm7
minichromosome maintenance deficient 7 (S. cerevisiae)
chr9_+_6168638 0.243 ENSMUST00000058692.7
 Pdgfd
platelet-derived growth factor, D polypeptide
chr4_+_149518216 0.209 ENSMUST00000030839.6
 Ctnnbip1
catenin beta interacting protein 1
chr15_+_31276491 0.195 ENSMUST00000068987.5
 Fam136b-ps
family with sequence similarity 136, member B, pseudogene
chr1_+_120602405 0.182 ENSMUST00000079721.7
 En1
engrailed 1
chr18_-_3281712 0.112 ENSMUST00000182204.1
ENSMUST00000154705.1
ENSMUST00000182833.1
ENSMUST00000151084.1
 Crem



cAMP responsive element modulator



chr2_-_38287347 0.102 ENSMUST00000102787.3
 Dennd1a
DENN/MADD domain containing 1A
chr10_-_61979073 0.060 ENSMUST00000105453.1
ENSMUST00000105452.2
ENSMUST00000105454.2
 Col13a1


collagen, type XIII, alpha 1


chr7_-_100855403 0.009 ENSMUST00000156855.1
 Relt
RELT tumor necrosis factor receptor

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 23.3 GO:0014819 regulation of skeletal muscle contraction(GO:0014819)
3.1 9.4 GO:0072034 renal vesicle induction(GO:0072034)
2.6 10.3 GO:1901252 regulation of intracellular transport of viral material(GO:1901252)
2.4 12.0 GO:0071692 protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694)
2.1 10.5 GO:0051365 cellular response to potassium ion starvation(GO:0051365)
1.7 5.2 GO:2000564 CD8-positive, alpha-beta T cell proliferation(GO:0035740) negative regulation of regulatory T cell differentiation(GO:0045590) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
1.5 5.8 GO:0035026 leading edge cell differentiation(GO:0035026)
1.2 3.7 GO:0051464 positive regulation of cortisol secretion(GO:0051464)
1.2 4.9 GO:0038128 ERBB2 signaling pathway(GO:0038128)
1.1 3.2 GO:0003104 positive regulation of glomerular filtration(GO:0003104) cell communication by chemical coupling(GO:0010643)
0.9 1.9 GO:0007412 axon target recognition(GO:0007412)
0.9 4.6 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.7 3.7 GO:0015822 ornithine transport(GO:0015822)
0.7 4.9 GO:1990504 dense core granule exocytosis(GO:1990504)
0.7 2.0 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.6 10.9 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.6 2.3 GO:0006481 C-terminal protein methylation(GO:0006481)
0.6 2.3 GO:1904529 regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
0.5 2.6 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.5 4.0 GO:0016114 terpenoid biosynthetic process(GO:0016114)
0.5 2.0 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.5 5.8 GO:0045217 cell-cell junction maintenance(GO:0045217)
0.5 4.1 GO:0097369 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.5 1.4 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.4 2.1 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.4 3.8 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.4 4.6 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.4 3.4 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.4 2.1 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.3 2.7 GO:0005513 detection of calcium ion(GO:0005513)
0.3 1.3 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.3 11.1 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.3 1.2 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.3 11.6 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
0.3 7.3 GO:0032757 positive regulation of interleukin-8 production(GO:0032757)
0.3 4.8 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.3 1.1 GO:0002024 diet induced thermogenesis(GO:0002024)
0.3 9.7 GO:0050873 brown fat cell differentiation(GO:0050873)
0.2 2.7 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011)
0.2 10.1 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.2 0.9 GO:0008655 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.2 1.8 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.2 2.8 GO:0034142 toll-like receptor 4 signaling pathway(GO:0034142)
0.2 5.5 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 0.2 GO:0035696 monocyte extravasation(GO:0035696) regulation of monocyte extravasation(GO:2000437)
0.1 6.5 GO:0031102 neuron projection regeneration(GO:0031102) response to axon injury(GO:0048678)
0.1 1.7 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 0.8 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 1.4 GO:0046548 retinal rod cell development(GO:0046548)
0.1 3.5 GO:0042168 heme metabolic process(GO:0042168)
0.1 3.4 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.1 2.9 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.1 0.8 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.1 1.3 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.1 2.6 GO:0010996 response to auditory stimulus(GO:0010996)
0.1 0.9 GO:0006337 nucleosome disassembly(GO:0006337)
0.1 0.4 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.1 0.5 GO:0010649 regulation of cell communication by electrical coupling(GO:0010649) regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
0.1 13.2 GO:0048839 inner ear development(GO:0048839)
0.0 0.8 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.2 GO:0061743 motor learning(GO:0061743)
0.0 0.2 GO:0045657 positive regulation of monocyte differentiation(GO:0045657)
0.0 1.5 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 1.5 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.0 4.3 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 0.6 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.0 4.0 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 11.6 GO:0031092 platelet alpha granule membrane(GO:0031092)
1.5 5.8 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.9 12.0 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.8 3.8 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.5 2.8 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.4 21.1 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.4 6.2 GO:0031045 dense core granule(GO:0031045)
0.4 3.2 GO:0005916 fascia adherens(GO:0005916)
0.3 1.4 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.3 1.3 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.2 20.8 GO:0005604 basement membrane(GO:0005604)
0.2 3.4 GO:0071564 npBAF complex(GO:0071564)
0.2 3.6 GO:0032279 asymmetric synapse(GO:0032279)
0.2 6.8 GO:0043034 costamere(GO:0043034)
0.2 8.1 GO:0031941 filamentous actin(GO:0031941)
0.1 1.8 GO:0042555 MCM complex(GO:0042555)
0.1 1.5 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1 10.3 GO:0031225 anchored component of membrane(GO:0031225)
0.1 0.8 GO:0000243 commitment complex(GO:0000243)
0.1 14.6 GO:0070382 exocytic vesicle(GO:0070382)
0.0 3.4 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.1 GO:0034707 chloride channel complex(GO:0034707)
0.0 2.2 GO:0005581 collagen trimer(GO:0005581)
0.0 0.6 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 8.9 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 4.1 GO:0055037 recycling endosome(GO:0055037)
0.0 2.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 8.5 GO:0043235 receptor complex(GO:0043235)
0.0 4.8 GO:0001650 fibrillar center(GO:0001650)
0.0 0.9 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 2.5 GO:0005884 actin filament(GO:0005884)
0.0 0.8 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.2 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 9.4 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 3.9 GO:0016607 nuclear speck(GO:0016607)
0.0 1.7 GO:0005802 trans-Golgi network(GO:0005802)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 21.1 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
1.6 4.8 GO:0016748 succinyltransferase activity(GO:0016748)
1.0 2.9 GO:0019002 GMP binding(GO:0019002)
0.9 3.7 GO:0004966 galanin receptor activity(GO:0004966)
0.9 3.7 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.9 4.6 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.9 10.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.8 3.2 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075) gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.7 4.0 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.6 2.3 GO:0003880 protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
0.6 7.3 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.5 4.1 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.5 1.9 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.4 5.3 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.4 16.5 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.3 1.4 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.3 9.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.2 10.1 GO:0017080 sodium channel regulator activity(GO:0017080)
0.2 15.7 GO:0005518 collagen binding(GO:0005518)
0.2 1.3 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.2 0.9 GO:0004849 uridine kinase activity(GO:0004849)
0.2 2.3 GO:0031005 filamin binding(GO:0031005)
0.2 10.9 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.2 2.7 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.2 2.8 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.2 2.2 GO:0002162 dystroglycan binding(GO:0002162)
0.1 1.7 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.1 1.4 GO:0015929 hexosaminidase activity(GO:0015929)
0.1 1.5 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.1 2.1 GO:0042056 chemoattractant activity(GO:0042056)
0.1 9.4 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.1 1.3 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 9.3 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.1 0.9 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 3.4 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.1 6.0 GO:0008013 beta-catenin binding(GO:0008013)
0.1 3.8 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 3.5 GO:0020037 heme binding(GO:0020037)
0.1 2.7 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 1.8 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 5.0 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 1.5 GO:0016876 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 2.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 2.1 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 9.3 GO:0003924 GTPase activity(GO:0003924)
0.0 0.6 GO:0031402 voltage-gated sodium channel activity(GO:0005248) sodium ion binding(GO:0031402)
0.0 9.2 GO:0005509 calcium ion binding(GO:0005509)
0.0 1.1 GO:0005254 chloride channel activity(GO:0005254)
0.0 0.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.8 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 2.6 GO:0003714 transcription corepressor activity(GO:0003714)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 34.1 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.2 21.8 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.2 5.2 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.2 10.5 PID_ATF2_PATHWAY ATF-2 transcription factor network
0.1 1.5 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 2.7 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.1 5.8 PID_TGFBR_PATHWAY TGF-beta receptor signaling
0.1 3.2 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.1 2.9 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.1 1.9 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.1 5.2 PID_MTOR_4PATHWAY mTOR signaling pathway
0.0 1.8 PID_ATR_PATHWAY ATR signaling pathway
0.0 3.4 PID_E2F_PATHWAY E2F transcription factor network
0.0 1.3 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.0 0.2 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 21.1 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.5 9.0 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.3 5.2 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.2 4.8 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.2 4.6 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.2 1.2 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.2 4.0 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.2 10.9 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 11.4 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 2.3 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 1.8 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.1 2.7 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.1 3.7 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 2.2 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.1 7.2 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 2.7 REACTOME_IL_RECEPTOR_SHC_SIGNALING Genes involved in Interleukin receptor SHC signaling
0.1 1.5 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.1 3.4 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 0.9 REACTOME_PYRIMIDINE_METABOLISM Genes involved in Pyrimidine metabolism
0.0 1.6 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.5 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.0 1.3 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase