---

Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr3_-_85722474	20.948	ENSMUST00000119077.1	Fam160a1	family with sequence similarity 160, member A1
chr13_+_94083490	14.384	ENSMUST00000156071.1	Lhfpl2	lipoma HMGIC fusion partner-like 2
chr15_-_75894474	9.802	ENSMUST00000023237.6	Naprt1	nicotinate phosphoribosyltransferase domain containing 1
chr1_+_139454747	9.268	ENSMUST00000053364.8 ENSMUST00000097554.3	Aspm	asp (abnormal spindle)-like, microcephaly associated (Drosophila)
chr5_+_139423151	6.658	ENSMUST00000066211.4	Gper1	G protein-coupled estrogen receptor 1
chr9_+_65141154	6.543	ENSMUST00000034961.4	Igdcc3	immunoglobulin superfamily, DCC subclass, member 3
chrX_-_142966709	6.302	ENSMUST00000041317.2	Ammecr1	Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr7_-_80115294	6.195	ENSMUST00000107384.3	Idh2	isocitrate dehydrogenase 2 (NADP+), mitochondrial
chr7_-_126676357	5.982	ENSMUST00000106371.1 ENSMUST00000106372.3 ENSMUST00000155419.1	Sult1a1	sulfotransferase family 1A, phenol-preferring, member 1
chr15_-_82244716	5.597	ENSMUST00000089155.4 ENSMUST00000089157.3	Cenpm	centromere protein M
chr4_-_32950813	5.065	ENSMUST00000084750.1 ENSMUST00000084748.2	Ankrd6	ankyrin repeat domain 6
chr9_+_72958785	4.989	ENSMUST00000098567.2 ENSMUST00000034734.8	Dyx1c1	dyslexia susceptibility 1 candidate 1 homolog (human)
chr7_-_126676428	4.875	ENSMUST00000106373.1	Sult1a1	sulfotransferase family 1A, phenol-preferring, member 1
chr18_+_56432116	4.824	ENSMUST00000070166.5	Gramd3	GRAM domain containing 3
chrX_+_169685191	4.198	ENSMUST00000112104.1 ENSMUST00000112107.1	Mid1	midline 1
chr3_+_94398517	3.305	ENSMUST00000050975.3	Lingo4	leucine rich repeat and Ig domain containing 4
chr10_-_128180265	3.294	ENSMUST00000099139.1	Rbms2	RNA binding motif, single stranded interacting protein 2
chr15_+_98571004	3.253	ENSMUST00000023728.6	4930415O20Rik	RIKEN cDNA 4930415O20 gene
chr8_+_57455898	2.665	ENSMUST00000034023.3	Scrg1	scrapie responsive gene 1
chr2_+_131491764	2.614	ENSMUST00000028806.5 ENSMUST00000110179.2 ENSMUST00000110189.2 ENSMUST00000110182.2 ENSMUST00000110183.2 ENSMUST00000110186.2 ENSMUST00000110188.1	Smox	spermine oxidase
chr3_-_37724321	2.432	ENSMUST00000108105.1 ENSMUST00000079755.4 ENSMUST00000099128.1	Gm5148	predicted gene 5148
chr17_-_56716788	2.215	ENSMUST00000067931.5	Vmac	vimentin-type intermediate filament associated coiled-coil protein
chr1_+_136467958	2.190	ENSMUST00000047817.6	Kif14	kinesin family member 14
chr3_+_88207308	2.116	ENSMUST00000180582.1	Gm3764	predicted gene 3764
chr7_-_141168671	1.976	ENSMUST00000106033.3	Rnh1	ribonuclease/angiogenin inhibitor 1
chr8_-_4275886	1.884	ENSMUST00000003029.7	Timm44	translocase of inner mitochondrial membrane 44
chr2_+_106693185	1.755	ENSMUST00000111063.1	Mpped2	metallophosphoesterase domain containing 2
chr2_-_13271419	1.735	ENSMUST00000028059.2	Rsu1	Ras suppressor protein 1
chr2_-_13271268	1.733	ENSMUST00000137670.1 ENSMUST00000114791.2	Rsu1	Ras suppressor protein 1
chr17_-_56717681	1.637	ENSMUST00000164907.1	Vmac	vimentin-type intermediate filament associated coiled-coil protein
chr1_-_118982551	1.564	ENSMUST00000159678.1	Gli2	GLI-Kruppel family member GLI2
chr3_+_130068390	1.460	ENSMUST00000076703.6	Gm9396	predicted gene 9396
chr4_+_133176336	1.440	ENSMUST00000105912.1	Wasf2	WAS protein family, member 2
chr11_-_69695521	1.255	ENSMUST00000181261.1	Tnfsf12	tumor necrosis factor (ligand) superfamily, member 12
chr13_+_104229366	1.192	ENSMUST00000022227.6	Cenpk	centromere protein K
chr6_+_38534823	1.171	ENSMUST00000019833.4	1110001J03Rik	RIKEN cDNA 1110001J03 gene
chr6_+_48537560	1.069	ENSMUST00000040361.5	Atp6v0e2	ATPase, H+ transporting, lysosomal V0 subunit E2
chr10_+_24595623	0.804	ENSMUST00000176228.1 ENSMUST00000129142.1	Ctgf	connective tissue growth factor
chr4_+_11758147	0.783	ENSMUST00000029871.5 ENSMUST00000108303.1	Cdh17	cadherin 17
chr15_-_76206309	0.778	ENSMUST00000073418.6 ENSMUST00000171634.1 ENSMUST00000076442.5	Plec	plectin
chr14_+_57798182	0.689	ENSMUST00000111269.1	Sap18	Sin3-associated polypeptide 18
chr4_-_43030440	0.685	ENSMUST00000135660.1	Stoml2	stomatin (Epb7.2)-like 2
chr7_+_30232310	0.648	ENSMUST00000108193.1 ENSMUST00000108192.1	Polr2i	polymerase (RNA) II (DNA directed) polypeptide I
chr9_+_104002546	0.602	ENSMUST00000035167.8 ENSMUST00000117054.1	Nphp3	nephronophthisis 3 (adolescent)
chr5_-_106926245	0.585	ENSMUST00000117588.1	Hfm1	HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae)
chr6_-_115675871	0.548	ENSMUST00000112949.1	Raf1	v-raf-leukemia viral oncogene 1
chr12_+_30584429	0.544	ENSMUST00000057151.8	Tmem18	transmembrane protein 18
chr16_-_45724600	0.447	ENSMUST00000096057.4	Tagln3	transgelin 3
chr12_+_84773262	0.423	ENSMUST00000021667.5	Isca2	iron-sulfur cluster assembly 2 homolog (S. cerevisiae)
chr8_+_84831522	0.417	ENSMUST00000036734.5	Gadd45gip1	growth arrest and DNA-damage-inducible, gamma interacting protein 1
chr11_-_99230998	0.403	ENSMUST00000103133.3	Smarce1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
chr9_-_70503718	0.380	ENSMUST00000034739.5	Rnf111	ring finger 111
chr10_-_78487842	0.370	ENSMUST00000069431.4	Gm9978	predicted gene 9978
chr8_+_69832633	0.306	ENSMUST00000131637.2 ENSMUST00000081503.6	Pbx4	pre B cell leukemia homeobox 4
chr5_+_21543525	0.285	ENSMUST00000035651.4	Lrrc17	leucine rich repeat containing 17
chr14_+_58893465	0.284	ENSMUST00000079960.1	Rpl13-ps3	ribosomal protein L13, pseudogene 3
chr17_+_25133385	0.241	ENSMUST00000040729.2	Clcn7	chloride channel 7
chr19_-_23075853	0.221	ENSMUST00000181623.1	C330002G04Rik	RIKEN cDNA C330002G04 gene
chr17_+_40811089	0.192	ENSMUST00000024721.7	Rhag	Rhesus blood group-associated A glycoprotein
chr8_+_71951038	0.184	ENSMUST00000131237.1 ENSMUST00000136516.1 ENSMUST00000109997.2 ENSMUST00000132848.1	Zfp961	zinc finger protein 961
chr19_-_55315980	0.162	ENSMUST00000076891.5	Zdhhc6	zinc finger, DHHC domain containing 6
chrY_-_6237995	0.157	ENSMUST00000177612.1	Gm21746	predicted gene, 21746
chr9_+_119341487	0.157	ENSMUST00000175743.1 ENSMUST00000176397.1	Acaa1a	acetyl-Coenzyme A acyltransferase 1A
chr11_-_87826023	0.140	ENSMUST00000103177.3	Lpo	lactoperoxidase
chr7_-_101903783	0.137	ENSMUST00000106969.1	Tomt	transmembrane O-methyltransferase
chr2_+_158028481	0.123	ENSMUST00000103123.3	Rprd1b	regulation of nuclear pre-mRNA domain containing 1B
chr5_+_23787691	0.118	ENSMUST00000030852.6 ENSMUST00000120869.1 ENSMUST00000117783.1 ENSMUST00000115113.2	Rint1	RAD50 interactor 1
chr16_-_18235074	0.069	ENSMUST00000076957.5	Zdhhc8	zinc finger, DHHC domain containing 8
chr14_+_57798156	0.057	ENSMUST00000128764.1	Sap18	Sin3-associated polypeptide 18
chr9_+_98422961	0.040	ENSMUST00000052068.9	Rbp1	retinol binding protein 1, cellular
chr10_+_100488289	0.006	ENSMUST00000164751.1	Cep290	centrosomal protein 290
chr5_-_62765618	0.002	ENSMUST00000159470.1	Arap2	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.1	6.2	GO:0006097	glyoxylate cycle(GO:0006097) negative regulation of glial cell migration(GO:1903976)
1.9	9.3	GO:0051661	maintenance of centrosome location(GO:0051661)
1.7	6.7	GO:1904706	regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579) negative regulation of vascular smooth muscle cell proliferation(GO:1904706) positive regulation of vascular smooth muscle cell differentiation(GO:1905065)
1.0	10.9	GO:0051923	sulfation(GO:0051923)
0.5	2.2	GO:0021698	cerebellar cortex structural organization(GO:0021698)
0.5	2.6	GO:0046208	spermine catabolic process(GO:0046208)
0.5	4.2	GO:0035372	protein localization to microtubule(GO:0035372)
0.5	5.0	GO:0036159	outer dynein arm assembly(GO:0036158) inner dynein arm assembly(GO:0036159)
0.4	1.6	GO:0060032	notochord regression(GO:0060032)
0.3	5.1	GO:2000096	positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.3	0.8	GO:0002314	germinal center B cell differentiation(GO:0002314)
0.2	0.7	GO:1990046	positive regulation of mitochondrial DNA replication(GO:0090297) regulation of cardiolipin metabolic process(GO:1900208) positive regulation of cardiolipin metabolic process(GO:1900210) stress-induced mitochondrial fusion(GO:1990046)
0.2	0.8	GO:0070318	positive regulation of G0 to G1 transition(GO:0070318)
0.2	0.6	GO:0035469	determination of pancreatic left/right asymmetry(GO:0035469) maintenance of organ identity(GO:0048496)
0.2	0.8	GO:0031581	hemidesmosome assembly(GO:0031581)
0.2	0.5	GO:0071550	death-inducing signaling complex assembly(GO:0071550)
0.1	1.9	GO:0030150	protein import into mitochondrial matrix(GO:0030150)
0.1	0.3	GO:0001193	maintenance of transcriptional fidelity during DNA-templated transcription elongation(GO:0001192) maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter(GO:0001193)
0.1	1.4	GO:0035855	megakaryocyte development(GO:0035855)
0.1	0.4	GO:0097428	protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1	0.3	GO:0048539	bone marrow development(GO:0048539)
0.1	0.4	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1	5.6	GO:0050885	neuromuscular process controlling balance(GO:0050885)
0.1	0.6	GO:0000712	resolution of meiotic recombination intermediates(GO:0000712)
0.0	0.1	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0	3.5	GO:2000179	positive regulation of neural precursor cell proliferation(GO:2000179)
0.0	0.4	GO:1903862	positive regulation of oxidative phosphorylation(GO:1903862)
0.0	0.1	GO:0072425	signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434)
0.0	3.3	GO:0051965	positive regulation of synapse assembly(GO:0051965)
0.0	0.1	GO:0019614	catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.0	0.4	GO:0006337	nucleosome disassembly(GO:0006337)
0.0	0.2	GO:0015670	carbon dioxide transport(GO:0015670)
0.0	0.6	GO:0015991	ATP hydrolysis coupled proton transport(GO:0015991)
0.0	1.3	GO:2001238	positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.0	0.1	GO:0070940	dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0	0.0	GO:0006776	vitamin A metabolic process(GO:0006776)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.9	9.3	GO:0036449	microtubule minus-end(GO:0036449)
1.0	3.9	GO:0045098	type III intermediate filament(GO:0045098)
0.7	6.7	GO:0032591	dendritic spine membrane(GO:0032591)
0.7	2.0	GO:0032311	angiogenin-PRI complex(GO:0032311)
0.2	0.6	GO:0097543	ciliary inversin compartment(GO:0097543)
0.1	9.0	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.1	1.6	GO:0097542	ciliary tip(GO:0097542)
0.1	1.4	GO:0031209	SCAR complex(GO:0031209)
0.1	1.1	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.1	0.7	GO:0061574	ASAP complex(GO:0061574)
0.1	0.8	GO:0030056	hemidesmosome(GO:0030056)
0.1	2.2	GO:0051233	spindle midzone(GO:0051233)
0.1	0.1	GO:0070939	Dsl1p complex(GO:0070939)
0.0	0.7	GO:0042101	T cell receptor complex(GO:0042101)
0.0	6.8	GO:0000776	kinetochore(GO:0000776)
0.0	0.5	GO:0031143	pseudopodium(GO:0031143)
0.0	6.4	GO:0005777	peroxisome(GO:0005777) microbody(GO:0042579)
0.0	0.4	GO:0071564	npBAF complex(GO:0071564)
0.0	0.8	GO:0005801	cis-Golgi network(GO:0005801)
0.0	0.3	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0	0.3	GO:0001741	XY body(GO:0001741)
0.0	2.4	GO:0044306	neuron projection terminus(GO:0044306)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.6	10.9	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
2.1	6.2	GO:0004450	isocitrate dehydrogenase (NADP+) activity(GO:0004450)
1.1	6.7	GO:0030284	estrogen receptor activity(GO:0030284)
0.9	2.6	GO:0046592	polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
0.3	0.8	GO:0035673	oligopeptide transmembrane transporter activity(GO:0035673)
0.3	3.9	GO:0019215	intermediate filament binding(GO:0019215)
0.2	2.0	GO:0008428	ribonuclease inhibitor activity(GO:0008428)
0.1	0.7	GO:1901612	phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612)
0.1	5.0	GO:0030331	estrogen receptor binding(GO:0030331)
0.1	0.4	GO:0032184	SUMO polymer binding(GO:0032184)
0.1	2.2	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1	1.6	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.1	1.0	GO:0030506	ankyrin binding(GO:0030506)
0.1	1.3	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.1	GO:0016206	catechol O-methyltransferase activity(GO:0016206)
0.0	9.3	GO:0005516	calmodulin binding(GO:0005516)
0.0	0.2	GO:0008410	CoA-transferase activity(GO:0008410)
0.0	0.8	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.0	4.2	GO:0051219	phosphoprotein binding(GO:0051219)
0.0	0.6	GO:0046961	proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0	0.5	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.0	1.9	GO:0051087	chaperone binding(GO:0051087)
0.0	0.4	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
0.0	0.2	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.0	0.4	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	5.1	ST_WNT_BETA_CATENIN_PATHWAY	Wnt/beta-catenin Pathway
0.1	1.6	PID_HEDGEHOG_2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.5	PID_TCR_RAS_PATHWAY	Ras signaling in the CD4+ TCR pathway
0.0	0.4	PID_ERB_GENOMIC_PATHWAY	Validated nuclear estrogen receptor beta network
0.0	1.4	PID_ECADHERIN_NASCENT_AJ_PATHWAY	E-cadherin signaling in the nascent adherens junction
0.0	0.8	PID_AMB2_NEUTROPHILS_PATHWAY	amb2 Integrin signaling
0.0	0.7	PID_HEDGEHOG_GLI_PATHWAY	Hedgehog signaling events mediated by Gli proteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.6	10.9	REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.3	6.2	REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.2	2.6	REACTOME_METABOLISM_OF_POLYAMINES	Genes involved in Metabolism of polyamines
0.1	3.5	REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.1	6.8	REACTOME_MITOTIC_PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	1.9	REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT	Genes involved in Mitochondrial Protein Import
0.0	0.5	REACTOME_RAF_MAP_KINASE_CASCADE	Genes involved in RAF/MAP kinase cascade
0.0	0.8	REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.8	REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.3	REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS	Genes involved in Viral Messenger RNA Synthesis

---