Z-value: 0.637
Transcription factors associated with Smad3:
Activity-expression correlation:
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Showing 1 to 20 of 83 entries
Promoter Score Refseq Gene Symbol Gene Name
chr5_-_53707532
11.044
ENSMUST00000031093.3
Cckar
cholecystokinin A receptor
chr7_+_51880312
5.042
ENSMUST00000145049.1
Gas2
growth arrest specific 2
chr14_-_62456286
4.831
ENSMUST00000165651.1 ENSMUST00000022501.3
Gucy1b2
guanylate cyclase 1, soluble, beta 2
chr13_-_21832194
4.304
ENSMUST00000102979.1
Hist1h4n
histone cluster 1, H4n
chr13_+_23533869
4.121
ENSMUST00000073261.2
Hist1h2af
histone cluster 1, H2af
chr18_-_74207771
3.952
ENSMUST00000040188.8 ENSMUST00000177604.1
Ska1
spindle and kinetochore associated complex subunit 1
chr13_-_21750505
3.235
ENSMUST00000102983.1
Hist1h4k
histone cluster 1, H4k
chr13_-_23551648
3.121
ENSMUST00000102971.1
Hist1h4f
histone cluster 1, H4f
chrX_-_7188713
3.105
ENSMUST00000004428.7
Clcn5
chloride channel 5
chr13_+_21735055
2.921
ENSMUST00000087714.4
Hist1h4j
histone cluster 1, H4j
chr13_+_23531044
2.877
ENSMUST00000102972.3
Hist1h4h
histone cluster 1, H4h
chr6_-_72235559
2.693
ENSMUST00000042646.7
Atoh8
atonal homolog 8 (Drosophila)
chr9_-_66514567
2.660
ENSMUST00000056890.8
Fbxl22
F-box and leucine-rich repeat protein 22
chr5_+_75574916
2.634
ENSMUST00000144270.1 ENSMUST00000005815.6
Kit
kit oncogene
chr5_+_114774677
2.500
ENSMUST00000102578.4
Ankrd13a
ankyrin repeat domain 13a
chr19_-_47919269
2.488
ENSMUST00000095998.5
Itprip
inositol 1,4,5-triphosphate receptor interacting protein
chr13_+_23581563
2.480
ENSMUST00000102968.1
Hist1h4d
histone cluster 1, H4d
chr13_+_22043189
2.364
ENSMUST00000110452.1
Hist1h2bj
histone cluster 1, H2bj
chr13_-_22042949
2.255
ENSMUST00000091741.4
Hist1h2ag
histone cluster 1, H2ag
chr13_-_21833575
2.201
ENSMUST00000081342.5
Hist1h2ap
histone cluster 1, H2ap
Gene overrepresentation in biological_process category:
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Showing 1 to 20 of 33 entries
Log-likelihood per target Total log-likelihood Term Description
1.0
18.9
GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.1
12.3
GO:0006342 chromatin silencing(GO:0006342)
3.7
11.0
GO:0090274 positive regulation of somatostatin secretion(GO:0090274)
0.0
6.4
GO:0007050 cell cycle arrest(GO:0007050)
0.1
4.8
GO:0006182 cGMP biosynthetic process(GO:0006182)
0.0
4.4
GO:0006334 nucleosome assembly(GO:0006334)
0.3
4.0
GO:0002227 innate immune response in mucosa(GO:0002227)
0.0
4.0
GO:0031110 regulation of microtubule polymerization or depolymerization(GO:0031110)
0.3
3.3
GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.1
3.1
GO:1902476 chloride transmembrane transport(GO:1902476)
0.2
2.7
GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.9
2.6
GO:1904347 intestine smooth muscle contraction(GO:0014827) regulation of gastro-intestinal system smooth muscle contraction(GO:1904304) regulation of small intestine smooth muscle contraction(GO:1904347) small intestine smooth muscle contraction(GO:1990770)
0.1
2.5
GO:0016578 histone deubiquitination(GO:0016578)
0.1
2.4
GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.4
1.6
GO:0046655 glycine biosynthetic process(GO:0006545) folic acid metabolic process(GO:0046655)
0.0
1.6
GO:0042742 defense response to bacterium(GO:0042742)
0.2
1.3
GO:0072697 protein localization to cell cortex(GO:0072697)
0.0
1.0
GO:0035082 axoneme assembly(GO:0035082)
0.3
0.9
GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.1
0.9
GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
Gene overrepresentation in cellular_component category:
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Showing 1 to 19 of 19 entries
Log-likelihood per target Total log-likelihood Term Description
0.5
14.9
GO:0000788 nuclear nucleosome(GO:0000788)
0.3
13.2
GO:0000786 nucleosome(GO:0000786)
0.1
8.8
GO:0043195 terminal bouton(GO:0043195)
0.0
6.3
GO:0000790 nuclear chromatin(GO:0000790)
0.3
4.8
GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.3
4.0
GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0
3.1
GO:0044306 neuron projection terminus(GO:0044306)
0.0
2.7
GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0
2.7
GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.2
2.5
GO:0070938 contractile ring(GO:0070938)
0.2
1.9
GO:0001520 outer dense fiber(GO:0001520)
0.0
1.2
GO:0001669 acrosomal vesicle(GO:0001669)
0.0
0.9
GO:0030018 Z disc(GO:0030018)
0.0
0.9
GO:0000118 histone deacetylase complex(GO:0000118)
0.1
0.6
GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0
0.5
GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0
0.3
GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0
0.2
GO:0031310 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.0
0.2
GO:0030056 hemidesmosome(GO:0030056)
Gene overrepresentation in molecular_function category:
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Showing 1 to 20 of 26 entries
Log-likelihood per target Total log-likelihood Term Description
0.1
21.4
GO:0042393 histone binding(GO:0042393)
0.2
11.0
GO:0008528 G-protein coupled peptide receptor activity(GO:0008528)
0.0
9.0
GO:0008017 microtubule binding(GO:0008017)
0.0
6.3
GO:0046982 protein heterodimerization activity(GO:0046982)
0.3
4.8
GO:0004383 guanylate cyclase activity(GO:0004383)
0.6
3.3
GO:0001069 regulatory region RNA binding(GO:0001069)
0.2
3.1
GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.4
2.8
GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1
2.7
GO:0070888 E-box binding(GO:0070888)
0.3
2.6
GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0
2.5
GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.5
1.6
GO:0051870 methotrexate binding(GO:0051870)
0.0
1.6
GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1
1.3
GO:0032794 GTPase activating protein binding(GO:0032794)
0.1
1.0
GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0
0.9
GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0
0.9
GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0
0.8
GO:0004601 peroxidase activity(GO:0004601)
0.0
0.7
GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0
0.6
GO:0070016 armadillo repeat domain binding(GO:0070016)
Gene overrepresentation in C2:CP category:
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Showing 1 to 5 of 5 entries
Log-likelihood per target Total log-likelihood Term Description
0.1
5.0
PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.0
2.6
PID_KIT_PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0
1.6
PID_E2F_PATHWAY E2F transcription factor network
0.0
1.6
NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0
0.5
NABA_COLLAGENS Genes encoding collagen proteins
Gene overrepresentation in C2:CP:REACTOME category:
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Showing 1 to 9 of 9 entries
