Motif ID: Sox11

Z-value: 0.545


Transcription factors associated with Sox11:

Gene SymbolEntrez IDGene Name
Sox11 ENSMUSG00000063632.5 Sox11

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sox11mm10_v2_chr12_-_27342696_273427260.664.4e-11Click!


Activity profile for motif Sox11.

activity profile for motif Sox11


Sorted Z-values histogram for motif Sox11

Sorted Z-values for motif Sox11



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox11

PNG image of the network

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Top targets:


Showing 1 to 20 of 67 entries
PromoterScoreRefseqGene SymbolGene Name
chr14_-_47418407 7.453 ENSMUST00000043296.3
 Dlgap5
discs, large (Drosophila) homolog-associated protein 5
chr9_+_65890237 6.448 ENSMUST00000045802.6
 2810417H13Rik
RIKEN cDNA 2810417H13 gene
chr6_-_23248264 5.039 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr2_-_79456750 5.016 ENSMUST00000041099.4
 Neurod1
neurogenic differentiation 1
chr1_+_82233112 4.564 ENSMUST00000023262.5
 Gm9747
predicted gene 9747
chr16_-_50330987 4.089 ENSMUST00000114488.1
 Bbx
bobby sox homolog (Drosophila)
chr5_+_64812336 4.049 ENSMUST00000166409.1
 Klf3
Kruppel-like factor 3 (basic)
chr2_+_154548888 3.879 ENSMUST00000045116.4
ENSMUST00000109709.3
 1700003F12Rik

RIKEN cDNA 1700003F12 gene

chr4_-_97584605 3.820 ENSMUST00000107067.1
 E130114P18Rik
RIKEN cDNA E130114P18 gene
chr4_-_97584612 3.798 ENSMUST00000107068.2
 E130114P18Rik
RIKEN cDNA E130114P18 gene
chr9_+_52047150 3.112 ENSMUST00000163153.1
 Rdx
radixin
chr7_+_70388305 2.727 ENSMUST00000080024.5
 B130024G19Rik
RIKEN cDNA B130024G19 gene
chr7_-_73541738 2.176 ENSMUST00000169922.2
 Chd2
chromodomain helicase DNA binding protein 2
chr11_-_64436653 2.063 ENSMUST00000177999.1
 F930015N05Rik
RIKEN cDNA F930015N05 gene
chr2_+_15055274 2.054 ENSMUST00000069870.3
 Arl5b
ADP-ribosylation factor-like 5B
chr11_-_50292302 1.911 ENSMUST00000059458.4
 Maml1
mastermind like 1 (Drosophila)
chr5_-_131616599 1.792 ENSMUST00000161804.1
 Auts2
autism susceptibility candidate 2
chr15_+_76797628 1.770 ENSMUST00000165535.2
 Gm17271
predicted gene, 17271
chr7_+_83631959 1.677 ENSMUST00000075418.7
ENSMUST00000117410.1
 Stard5

StAR-related lipid transfer (START) domain containing 5

chr10_+_17796256 1.656 ENSMUST00000037964.6
 Txlnb
taxilin beta

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 30 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.3 5.0 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.8 5.0 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 4.0 GO:0060348 bone development(GO:0060348)
0.4 3.1 GO:1902965 regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
0.1 2.7 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.1 2.2 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.6 1.9 GO:0003162 atrioventricular node development(GO:0003162)
0.6 1.8 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.1 1.7 GO:0070508 sterol import(GO:0035376) cholesterol import(GO:0070508)
0.0 1.6 GO:0043407 negative regulation of MAP kinase activity(GO:0043407)
0.3 1.5 GO:1904659 glucose transmembrane transport(GO:1904659)
0.0 1.5 GO:0010842 retina layer formation(GO:0010842)
0.1 1.3 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.4 1.2 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.2 0.9 GO:0030043 actin filament fragmentation(GO:0030043)
0.1 0.8 GO:2000009 negative regulation of protein localization to cell surface(GO:2000009)
0.0 0.8 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.8 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.8 GO:0002088 lens development in camera-type eye(GO:0002088)
0.2 0.6 GO:1990046 positive regulation of mitochondrial DNA replication(GO:0090297) regulation of cardiolipin metabolic process(GO:1900208) positive regulation of cardiolipin metabolic process(GO:1900210) stress-induced mitochondrial fusion(GO:1990046)

Gene overrepresentation in cellular_component category:

Showing 1 to 14 of 14 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 7.5 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 5.0 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.2 3.1 GO:0051286 cell tip(GO:0051286)
0.0 2.7 GO:0044295 axonal growth cone(GO:0044295)
0.4 1.9 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 1.3 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.4 1.2 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.8 GO:0005922 connexon complex(GO:0005922)
0.0 0.8 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.7 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 0.6 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 0.6 GO:0072487 MSL complex(GO:0072487)
0.0 0.6 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.1 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 23 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 7.5 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.1 5.0 GO:0070888 E-box binding(GO:0070888)
0.0 4.6 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 3.1 GO:0051117 ATPase binding(GO:0051117)
0.0 2.2 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.1 1.9 GO:0042605 peptide antigen binding(GO:0042605)
0.6 1.7 GO:0032052 bile acid binding(GO:0032052)
0.0 1.7 GO:0019905 syntaxin binding(GO:0019905)
0.0 1.6 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1 1.5 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.1 1.3 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 1.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.8 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.7 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.6 GO:1901612 phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612)
0.0 0.6 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.6 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.6 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.5 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.1 0.4 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)

Gene overrepresentation in C2:CP category:

Showing 1 to 7 of 7 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 7.5 PID_AURORA_A_PATHWAY Aurora A signaling
0.1 3.1 ST_GA13_PATHWAY G alpha 13 Pathway
0.1 2.7 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.9 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.0 1.3 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 1.2 NABA_COLLAGENS Genes encoding collagen proteins
0.0 0.9 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 8 of 8 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 5.0 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.1 3.1 REACTOME_RECYCLING_PATHWAY_OF_L1 Genes involved in Recycling pathway of L1
0.1 2.7 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.1 1.9 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 1.7 REACTOME_STEROID_HORMONES Genes involved in Steroid hormones
0.0 1.2 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.8 REACTOME_MRNA_3_END_PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.2 REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM Genes involved in Abacavir transport and metabolism