Motif ID: Sox11

Z-value: 0.545


Transcription factors associated with Sox11:

Gene SymbolEntrez IDGene Name
Sox11 ENSMUSG00000063632.5 Sox11

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sox11mm10_v2_chr12_-_27342696_273427260.664.4e-11Click!


Activity profile for motif Sox11.

activity profile for motif Sox11


Sorted Z-values histogram for motif Sox11

Sorted Z-values for motif Sox11



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox11

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_-_47418407 7.453 ENSMUST00000043296.3
Dlgap5
discs, large (Drosophila) homolog-associated protein 5
chr9_+_65890237 6.448 ENSMUST00000045802.6
2810417H13Rik
RIKEN cDNA 2810417H13 gene
chr6_-_23248264 5.039 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr2_-_79456750 5.016 ENSMUST00000041099.4
Neurod1
neurogenic differentiation 1
chr1_+_82233112 4.564 ENSMUST00000023262.5
Gm9747
predicted gene 9747
chr16_-_50330987 4.089 ENSMUST00000114488.1
Bbx
bobby sox homolog (Drosophila)
chr5_+_64812336 4.049 ENSMUST00000166409.1
Klf3
Kruppel-like factor 3 (basic)
chr2_+_154548888 3.879 ENSMUST00000045116.4
ENSMUST00000109709.3
1700003F12Rik

RIKEN cDNA 1700003F12 gene

chr4_-_97584605 3.820 ENSMUST00000107067.1
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr4_-_97584612 3.798 ENSMUST00000107068.2
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr9_+_52047150 3.112 ENSMUST00000163153.1
Rdx
radixin
chr7_+_70388305 2.727 ENSMUST00000080024.5
B130024G19Rik
RIKEN cDNA B130024G19 gene
chr7_-_73541738 2.176 ENSMUST00000169922.2
Chd2
chromodomain helicase DNA binding protein 2
chr11_-_64436653 2.063 ENSMUST00000177999.1
F930015N05Rik
RIKEN cDNA F930015N05 gene
chr2_+_15055274 2.054 ENSMUST00000069870.3
Arl5b
ADP-ribosylation factor-like 5B
chr11_-_50292302 1.911 ENSMUST00000059458.4
Maml1
mastermind like 1 (Drosophila)
chr5_-_131616599 1.792 ENSMUST00000161804.1
Auts2
autism susceptibility candidate 2
chr15_+_76797628 1.770 ENSMUST00000165535.2
Gm17271
predicted gene, 17271
chr7_+_83631959 1.677 ENSMUST00000075418.7
ENSMUST00000117410.1
Stard5

StAR-related lipid transfer (START) domain containing 5

chr10_+_17796256 1.656 ENSMUST00000037964.6
Txlnb
taxilin beta
chr16_-_38341812 1.627 ENSMUST00000114740.2
ENSMUST00000023501.8
Maats1

MYCBP-associated, testis expressed 1

chr17_-_29007925 1.601 ENSMUST00000009138.5
ENSMUST00000119274.1
Stk38

serine/threonine kinase 38

chr10_-_76110956 1.527 ENSMUST00000120757.1
Slc5a4b
solute carrier family 5 (neutral amino acid transporters, system A), member 4b
chr9_-_16378231 1.504 ENSMUST00000082170.5
Fat3
FAT tumor suppressor homolog 3 (Drosophila)
chr16_-_44558864 1.481 ENSMUST00000023370.4
Boc
biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein
chr13_-_41487306 1.480 ENSMUST00000021794.6
Nedd9
neural precursor cell expressed, developmentally down-regulated gene 9
chr14_-_52213379 1.330 ENSMUST00000140603.1
Chd8
chromodomain helicase DNA binding protein 8
chr5_-_148552783 1.279 ENSMUST00000079324.7
ENSMUST00000164904.1
Ubl3

ubiquitin-like 3

chr16_-_44558879 1.205 ENSMUST00000114634.1
Boc
biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein
chr1_-_45503282 1.153 ENSMUST00000086430.4
Col5a2
collagen, type V, alpha 2
chr6_-_42693030 1.040 ENSMUST00000045140.4
Fam115a
family with sequence similarity 115, member A
chr6_-_12109583 0.983 ENSMUST00000080891.5
Gm6578
predicted gene 6578
chr6_-_42693087 0.951 ENSMUST00000121083.1
Fam115a
family with sequence similarity 115, member A
chr12_-_54862783 0.896 ENSMUST00000078124.7
Cfl2
cofilin 2, muscle
chr2_-_36136602 0.884 ENSMUST00000122456.1
Rbm18
RNA binding motif protein 18
chrX_-_37104523 0.840 ENSMUST00000130324.1
Upf3b
UPF3 regulator of nonsense transcripts homolog B (yeast)
chr10_+_115569986 0.823 ENSMUST00000173620.1
A930009A15Rik
RIKEN cDNA A930009A15 gene
chrX_+_166344692 0.802 ENSMUST00000112223.1
ENSMUST00000112224.1
ENSMUST00000112229.2
ENSMUST00000112228.1
ENSMUST00000112227.2
ENSMUST00000112226.2
Gpm6b





glycoprotein m6b





chr10_-_14718191 0.786 ENSMUST00000020016.4
Gje1
gap junction protein, epsilon 1
chr7_-_55962466 0.777 ENSMUST00000032635.7
ENSMUST00000152649.1
Nipa2

non imprinted in Prader-Willi/Angelman syndrome 2 homolog (human)

chr16_+_8830093 0.752 ENSMUST00000023150.5
1810013L24Rik
RIKEN cDNA 1810013L24 gene
chr3_+_60877002 0.718 ENSMUST00000099086.2
Gm8325
predicted pseudogene 8325
chr1_+_44119952 0.714 ENSMUST00000114709.2
Bivm
basic, immunoglobulin-like variable motif containing
chrM_+_7005 0.686 ENSMUST00000082405.1
mt-Co2
mitochondrially encoded cytochrome c oxidase II
chr3_+_28805436 0.667 ENSMUST00000043867.5
Rpl22l1
ribosomal protein L22 like 1
chr2_-_36136773 0.651 ENSMUST00000028251.3
Rbm18
RNA binding motif protein 18
chr3_+_67430096 0.645 ENSMUST00000077271.6
ENSMUST00000161009.1
Gfm1

G elongation factor, mitochondrial 1

chr4_-_43030440 0.616 ENSMUST00000135660.1
Stoml2
stomatin (Epb7.2)-like 2
chr2_-_156111954 0.606 ENSMUST00000142960.2
ENSMUST00000136296.2
ENSMUST00000059647.5
ENSMUST00000109604.2
ENSMUST00000138068.1
ENSMUST00000128499.1
Cpne1

Rbm12



copine I

RNA binding motif protein 12



chr7_-_105737376 0.605 ENSMUST00000098148.4
Rrp8
ribosomal RNA processing 8, methyltransferase, homolog (yeast)
chr5_+_121795034 0.577 ENSMUST00000162327.1
Atxn2
ataxin 2
chr9_+_101074727 0.571 ENSMUST00000085177.3
Msl2
male-specific lethal 2 homolog (Drosophila)
chr10_+_119992916 0.497 ENSMUST00000105261.2
Grip1
glutamate receptor interacting protein 1
chr9_+_107888129 0.436 ENSMUST00000035202.2
Mon1a
MON1 homolog A (yeast)
chr13_+_24327415 0.407 ENSMUST00000167746.1
Cmah
cytidine monophospho-N-acetylneuraminic acid hydroxylase
chr2_-_86347764 0.312 ENSMUST00000099894.2
Olfr1055
olfactory receptor 1055
chr13_+_40859768 0.297 ENSMUST00000110191.2
Gcnt2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr4_-_123139929 0.249 ENSMUST00000030404.4
Ppie
peptidylprolyl isomerase E (cyclophilin E)
chr4_+_21848039 0.186 ENSMUST00000098238.2
ENSMUST00000108229.1
Sfrs18

serine/arginine-rich splicing factor 18

chr19_-_46969474 0.179 ENSMUST00000086961.7
Nt5c2
5'-nucleotidase, cytosolic II
chr16_+_65520503 0.155 ENSMUST00000176330.1
ENSMUST00000004964.8
ENSMUST00000176038.1
Pou1f1


POU domain, class 1, transcription factor 1


chrM_+_7759 0.150 ENSMUST00000082407.1
ENSMUST00000082408.1
mt-Atp8
mt-Atp6
mitochondrially encoded ATP synthase 8
mitochondrially encoded ATP synthase 6
chr11_+_4873951 0.095 ENSMUST00000038570.2
Nipsnap1
4-nitrophenylphosphatase domain and non-neuronal SNAP25-like protein homolog 1 (C. elegans)
chr10_+_24869982 0.084 ENSMUST00000092646.6
Med23
mediator complex subunit 23
chr11_-_106193511 0.021 ENSMUST00000007444.7
ENSMUST00000152008.1
ENSMUST00000103072.3
ENSMUST00000106867.1
Strada



STE20-related kinase adaptor alpha



chr13_-_99516537 0.017 ENSMUST00000064762.4
Map1b
microtubule-associated protein 1B
chr8_-_83442648 0.014 ENSMUST00000167525.1
Scoc
short coiled-coil protein

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 5.0 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.8 5.0 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.6 1.9 GO:0003162 atrioventricular node development(GO:0003162)
0.6 1.8 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.4 3.1 GO:1902965 regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
0.4 1.2 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.3 1.5 GO:1904659 glucose transmembrane transport(GO:1904659)
0.2 0.9 GO:0030043 actin filament fragmentation(GO:0030043)
0.2 0.6 GO:1990046 positive regulation of mitochondrial DNA replication(GO:0090297) regulation of cardiolipin metabolic process(GO:1900208) positive regulation of cardiolipin metabolic process(GO:1900210) stress-induced mitochondrial fusion(GO:1990046)
0.2 0.6 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.2 0.6 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.1 0.4 GO:0046381 CMP-N-acetylneuraminate metabolic process(GO:0046381)
0.1 1.3 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.1 2.2 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.1 1.7 GO:0070508 sterol import(GO:0035376) cholesterol import(GO:0070508)
0.1 2.7 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.1 0.6 GO:0046015 regulation of transcription by glucose(GO:0046015)
0.1 0.3 GO:0036438 maintenance of lens transparency(GO:0036438)
0.1 0.8 GO:2000009 negative regulation of protein localization to cell surface(GO:2000009)
0.1 0.2 GO:0060126 somatotropin secreting cell differentiation(GO:0060126)
0.0 1.5 GO:0010842 retina layer formation(GO:0010842)
0.0 0.8 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.6 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 0.1 GO:2000409 positive regulation of T cell extravasation(GO:2000409)
0.0 0.6 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.8 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 1.6 GO:0043407 negative regulation of MAP kinase activity(GO:0043407)
0.0 4.0 GO:0060348 bone development(GO:0060348)
0.0 0.2 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.8 GO:0002088 lens development in camera-type eye(GO:0002088)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0005588 collagen type V trimer(GO:0005588)
0.4 1.9 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.4 7.5 GO:0031616 spindle pole centrosome(GO:0031616)
0.2 3.1 GO:0051286 cell tip(GO:0051286)
0.1 0.6 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 0.6 GO:0072487 MSL complex(GO:0072487)
0.1 0.8 GO:0005922 connexon complex(GO:0005922)
0.0 0.7 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 2.7 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.6 GO:0042101 T cell receptor complex(GO:0042101)
0.0 1.3 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 5.0 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.8 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.1 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0032052 bile acid binding(GO:0032052)
0.1 0.4 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.1 5.0 GO:0070888 E-box binding(GO:0070888)
0.1 1.5 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.1 0.3 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 0.6 GO:1901612 phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612)
0.1 1.9 GO:0042605 peptide antigen binding(GO:0042605)
0.1 1.3 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 0.3 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 1.6 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.8 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 7.5 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.0 0.6 GO:0050692 DBD domain binding(GO:0050692)
0.0 1.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.7 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.6 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 4.6 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 3.1 GO:0051117 ATPase binding(GO:0051117)
0.0 0.5 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.6 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 1.7 GO:0019905 syntaxin binding(GO:0019905)
0.0 2.2 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.0 0.2 GO:0008253 5'-nucleotidase activity(GO:0008253)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 7.5 PID_AURORA_A_PATHWAY Aurora A signaling
0.1 2.7 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.1 3.1 ST_GA13_PATHWAY G alpha 13 Pathway
0.0 1.9 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.0 1.2 NABA_COLLAGENS Genes encoding collagen proteins
0.0 0.9 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.3 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.0 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.1 1.7 REACTOME_STEROID_HORMONES Genes involved in Steroid hormones
0.1 1.9 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 2.7 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.1 3.1 REACTOME_RECYCLING_PATHWAY_OF_L1 Genes involved in Recycling pathway of L1
0.0 1.2 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.8 REACTOME_MRNA_3_END_PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.2 REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM Genes involved in Abacavir transport and metabolism