Motif ID: Sox13

Z-value: 0.339


Transcription factors associated with Sox13:

Gene SymbolEntrez IDGene Name
Sox13 ENSMUSG00000070643.5 Sox13

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sox13mm10_v2_chr1_-_133424377_1334244040.271.6e-02Click!


Activity profile for motif Sox13.

activity profile for motif Sox13


Sorted Z-values histogram for motif Sox13

Sorted Z-values for motif Sox13



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox13

PNG image of the network

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Top targets:


Showing 1 to 20 of 39 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_-_84773381 7.714 ENSMUST00000109764.1
Nfix
nuclear factor I/X
chr1_+_19103022 4.053 ENSMUST00000037294.7
Tfap2d
transcription factor AP-2, delta
chr7_+_96210107 3.593 ENSMUST00000138760.1
Tenm4
teneurin transmembrane protein 4
chr18_+_69593361 2.319 ENSMUST00000114978.2
ENSMUST00000114977.1
Tcf4

transcription factor 4

chr2_+_25180737 1.920 ENSMUST00000104999.2
Nrarp
Notch-regulated ankyrin repeat protein
chr12_+_36314160 1.828 ENSMUST00000041407.5
Sostdc1
sclerostin domain containing 1
chr8_-_11008458 1.781 ENSMUST00000040514.6
Irs2
insulin receptor substrate 2
chr3_+_34649987 1.291 ENSMUST00000099151.2
Sox2
SRY-box containing gene 2
chr7_-_132813095 1.091 ENSMUST00000106165.1
Fam53b
family with sequence similarity 53, member B
chr17_-_68004075 1.062 ENSMUST00000024840.5
Arhgap28
Rho GTPase activating protein 28
chr18_+_37355271 1.041 ENSMUST00000051163.1
Pcdhb8
protocadherin beta 8
chr18_+_64887690 1.040 ENSMUST00000163516.1
Nedd4l
neural precursor cell expressed, developmentally down-regulated gene 4-like
chr2_-_36104060 0.871 ENSMUST00000112961.3
ENSMUST00000112966.3
Lhx6

LIM homeobox protein 6

chr7_+_24271568 0.606 ENSMUST00000032696.6
Zfp93
zinc finger protein 93
chr15_-_50890396 0.593 ENSMUST00000185183.1
Trps1
trichorhinophalangeal syndrome I (human)
chr1_-_93101825 0.535 ENSMUST00000112958.2
Kif1a
kinesin family member 1A
chr7_-_84679346 0.510 ENSMUST00000069537.2
ENSMUST00000178385.1
Zfand6

zinc finger, AN1-type domain 6

chr5_-_8367982 0.503 ENSMUST00000088761.4
ENSMUST00000115386.1
ENSMUST00000050166.7
ENSMUST00000046838.7
ENSMUST00000115388.2
ENSMUST00000088744.5
ENSMUST00000115385.1
Adam22






a disintegrin and metallopeptidase domain 22






chr11_-_77489666 0.499 ENSMUST00000037593.7
ENSMUST00000092892.3
Ankrd13b

ankyrin repeat domain 13b

chr7_-_105787567 0.493 ENSMUST00000144189.1
Dchs1
dachsous 1 (Drosophila)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 23 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 7.7 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1 4.1 GO:0030901 midbrain development(GO:0030901)
0.9 3.6 GO:0032289 central nervous system myelin formation(GO:0032289) cardiac cell fate specification(GO:0060912)
0.2 2.3 GO:0042118 endothelial cell activation(GO:0042118)
0.2 1.9 GO:0014807 regulation of somitogenesis(GO:0014807)
0.6 1.8 GO:2000016 negative regulation of determination of dorsal identity(GO:2000016)
0.2 1.8 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.2 1.3 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.3 1.1 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.0 1.1 GO:0035411 catenin import into nucleus(GO:0035411)
0.2 1.0 GO:2001286 regulation of caveolin-mediated endocytosis(GO:2001286)
0.0 1.0 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 0.9 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.1 0.5 GO:0003192 mitral valve formation(GO:0003192) cell migration involved in endocardial cushion formation(GO:0003273) condensed mesenchymal cell proliferation(GO:0072137)
0.0 0.5 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.5 GO:0006625 protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0 0.5 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.1 0.3 GO:0016240 autophagosome docking(GO:0016240)
0.0 0.3 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.3 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)

Gene overrepresentation in cellular_component category:

Showing 1 to 3 of 3 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 8.3 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.8 GO:0005871 kinesin complex(GO:0005871)
0.1 0.3 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)

Gene overrepresentation in molecular_function category:

Showing 1 to 10 of 10 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 8.2 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.6 2.3 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.3 1.8 GO:0098821 BMP receptor activity(GO:0098821)
0.0 1.8 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 1.3 GO:0035198 miRNA binding(GO:0035198)
0.1 1.0 GO:0019871 potassium channel inhibitor activity(GO:0019870) sodium channel inhibitor activity(GO:0019871)
0.1 0.4 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.3 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.3 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.2 GO:0004111 creatine kinase activity(GO:0004111)

Gene overrepresentation in C2:CP category:

Showing 1 to 5 of 5 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.3 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.0 1.8 PID_EPO_PATHWAY EPO signaling pathway
0.0 1.6 PID_BMP_PATHWAY BMP receptor signaling
0.0 1.0 PID_TGFBR_PATHWAY TGF-beta receptor signaling
0.0 0.3 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 3 of 3 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.3 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.1 1.8 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.0 0.3 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects