Motif ID: Sox14

Z-value: 1.058


Transcription factors associated with Sox14:

Gene SymbolEntrez IDGene Name
Sox14 ENSMUSG00000053747.8 Sox14

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sox14mm10_v2_chr9_-_99876147_998761930.019.2e-01Click!


Activity profile for motif Sox14.

activity profile for motif Sox14


Sorted Z-values histogram for motif Sox14

Sorted Z-values for motif Sox14



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox14

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_23248264 17.592 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr12_+_109546333 10.055 ENSMUST00000166636.2
Meg3
maternally expressed 3
chr12_+_109546409 9.206 ENSMUST00000143847.1
Meg3
maternally expressed 3
chr4_+_62965560 8.717 ENSMUST00000030043.6
ENSMUST00000107415.1
ENSMUST00000064814.5
Zfp618


zinc finger protein 618


chr12_+_109545390 8.203 ENSMUST00000146701.1
Meg3
maternally expressed 3
chr4_+_13751297 7.728 ENSMUST00000105566.2
Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr10_-_6980376 7.152 ENSMUST00000105617.1
Ipcef1
interaction protein for cytohesin exchange factors 1
chr4_+_102254739 6.192 ENSMUST00000106907.2
Pde4b
phosphodiesterase 4B, cAMP specific
chr11_+_67586520 5.902 ENSMUST00000108682.2
Gas7
growth arrest specific 7
chr13_-_58113592 5.793 ENSMUST00000160860.1
Klhl3
kelch-like 3
chr11_+_67586675 5.411 ENSMUST00000108680.1
Gas7
growth arrest specific 7
chr13_-_14523178 5.223 ENSMUST00000110516.2
Hecw1
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
chrX_-_167209149 4.910 ENSMUST00000112176.1
Tmsb4x
thymosin, beta 4, X chromosome
chr16_+_52031549 4.871 ENSMUST00000114471.1
Cblb
Casitas B-lineage lymphoma b
chr14_-_98169542 4.562 ENSMUST00000069334.7
ENSMUST00000071533.6
Dach1

dachshund 1 (Drosophila)

chr2_-_102186322 4.502 ENSMUST00000111222.1
ENSMUST00000058790.5
Ldlrad3

low density lipoprotein receptor class A domain containing 3

chr12_-_32061221 4.307 ENSMUST00000003079.5
ENSMUST00000036497.9
Prkar2b

protein kinase, cAMP dependent regulatory, type II beta

chr9_+_65265173 4.171 ENSMUST00000048762.1
Cilp
cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
chr1_-_12991109 4.055 ENSMUST00000115403.2
ENSMUST00000115402.1
Slco5a1

solute carrier organic anion transporter family, member 5A1

chr14_-_104467984 4.020 ENSMUST00000053016.8
Pou4f1
POU domain, class 4, transcription factor 1
chr2_+_143546144 3.991 ENSMUST00000028905.9
Pcsk2
proprotein convertase subtilisin/kexin type 2
chr13_+_93304940 3.911 ENSMUST00000109497.1
ENSMUST00000109498.1
ENSMUST00000060490.4
ENSMUST00000109492.1
ENSMUST00000109496.1
ENSMUST00000109495.1
Homer1





homer homolog 1 (Drosophila)





chr13_+_5861489 3.806 ENSMUST00000000080.6
Klf6
Kruppel-like factor 6
chr15_+_88751649 3.512 ENSMUST00000041297.8
Zbed4
zinc finger, BED domain containing 4
chr1_+_146497614 3.399 ENSMUST00000132847.1
ENSMUST00000166814.1
Brinp3

bone morphogenetic protein/retinoic acid inducible neural specific 3

chr14_-_7483762 3.366 ENSMUST00000164366.1
Gm3752
predicted gene 3752
chr17_-_79355082 3.314 ENSMUST00000068958.7
Cdc42ep3
CDC42 effector protein (Rho GTPase binding) 3
chr6_-_48445678 3.252 ENSMUST00000114556.1
Zfp467
zinc finger protein 467
chr13_-_89742244 3.252 ENSMUST00000109543.2
ENSMUST00000159337.1
ENSMUST00000159910.1
ENSMUST00000109544.2
Vcan



versican



chr7_-_144939823 3.235 ENSMUST00000093962.4
Ccnd1
cyclin D1
chr15_-_95528702 3.178 ENSMUST00000166170.1
Nell2
NEL-like 2
chr1_+_131962941 3.111 ENSMUST00000177943.1
Slc45a3
solute carrier family 45, member 3
chr11_-_12037391 3.062 ENSMUST00000093321.5
Grb10
growth factor receptor bound protein 10
chr6_-_99028251 3.050 ENSMUST00000177437.1
ENSMUST00000177229.1
ENSMUST00000113321.1
ENSMUST00000124058.1
Foxp1



forkhead box P1



chr6_-_82774448 3.014 ENSMUST00000000642.4
Hk2
hexokinase 2
chr6_+_120666388 2.973 ENSMUST00000112686.1
Cecr2
cat eye syndrome chromosome region, candidate 2
chr5_+_108065742 2.899 ENSMUST00000081567.4
ENSMUST00000170319.1
ENSMUST00000112626.1
Mtf2


metal response element binding transcription factor 2


chr15_-_95528228 2.823 ENSMUST00000075275.2
Nell2
NEL-like 2
chr16_-_96082513 2.795 ENSMUST00000113827.1
Brwd1
bromodomain and WD repeat domain containing 1
chr3_-_88458876 2.713 ENSMUST00000147200.1
ENSMUST00000169222.1
Sema4a

sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A

chr18_-_46198810 2.695 ENSMUST00000167364.1
Trim36
tripartite motif-containing 36
chr3_-_88459047 2.685 ENSMUST00000165898.1
ENSMUST00000127436.1
Sema4a

sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A

chr11_+_119022962 2.584 ENSMUST00000026662.7
Cbx2
chromobox 2
chr14_+_59201418 2.574 ENSMUST00000140136.2
ENSMUST00000142326.1
Rcbtb1

regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1

chr5_+_108065696 2.488 ENSMUST00000172045.1
Mtf2
metal response element binding transcription factor 2
chr6_-_48445373 2.432 ENSMUST00000114563.1
ENSMUST00000114558.1
ENSMUST00000101443.3
ENSMUST00000114564.1
Zfp467



zinc finger protein 467



chr8_+_45507768 2.431 ENSMUST00000067065.7
ENSMUST00000098788.3
ENSMUST00000067107.7
ENSMUST00000171337.2
ENSMUST00000138049.1
ENSMUST00000141039.1
Sorbs2





sorbin and SH3 domain containing 2





chr10_+_37139558 2.428 ENSMUST00000062667.3
5930403N24Rik
RIKEN cDNA 5930403N24 gene
chr7_+_90426312 2.405 ENSMUST00000061391.7
Ccdc89
coiled-coil domain containing 89
chr3_-_33083016 2.398 ENSMUST00000078226.3
ENSMUST00000108224.1
Pex5l

peroxisomal biogenesis factor 5-like

chr5_-_28467093 2.372 ENSMUST00000002708.3
Shh
sonic hedgehog
chr11_-_69822144 2.366 ENSMUST00000045771.6
Spem1
sperm maturation 1
chr3_-_105053125 2.353 ENSMUST00000077548.5
Cttnbp2nl
CTTNBP2 N-terminal like
chr1_-_60566708 2.328 ENSMUST00000027168.5
ENSMUST00000090293.4
ENSMUST00000140485.1
Raph1


Ras association (RalGDS/AF-6) and pleckstrin homology domains 1


chr11_+_24076529 2.285 ENSMUST00000148087.1
Gm12063
predicted gene 12063
chr8_-_105289465 2.241 ENSMUST00000171788.1
ENSMUST00000014981.6
4931428F04Rik

RIKEN cDNA 4931428F04 gene

chr8_+_36993551 2.216 ENSMUST00000098825.3
AI429214
expressed sequence AI429214
chr13_+_93304799 2.178 ENSMUST00000080127.5
Homer1
homer homolog 1 (Drosophila)
chr9_-_35570393 2.164 ENSMUST00000115110.4
Hyls1
hydrolethalus syndrome 1
chr10_-_29144194 2.134 ENSMUST00000070359.2
Gm9996
predicted gene 9996
chr9_-_70503718 2.133 ENSMUST00000034739.5
Rnf111
ring finger 111
chr9_+_53771499 2.130 ENSMUST00000048670.8
Slc35f2
solute carrier family 35, member F2
chr12_-_10900296 2.074 ENSMUST00000085735.2
Pgk1-rs7
phosphoglycerate kinase-1, related sequence-7
chr6_+_54039558 2.040 ENSMUST00000046856.7
Chn2
chimerin (chimaerin) 2
chr4_-_109202217 2.018 ENSMUST00000160774.1
ENSMUST00000030288.7
ENSMUST00000162787.2
Osbpl9


oxysterol binding protein-like 9


chr18_-_46212595 2.013 ENSMUST00000037011.4
Trim36
tripartite motif-containing 36
chr5_-_110387090 2.009 ENSMUST00000056124.6
Fbrsl1
fibrosin-like 1
chr1_+_65186727 1.954 ENSMUST00000097707.4
ENSMUST00000081154.7
Pikfyve

phosphoinositide kinase, FYVE finger containing

chr12_-_54986328 1.936 ENSMUST00000038926.6
Baz1a
bromodomain adjacent to zinc finger domain 1A
chr3_+_55461758 1.931 ENSMUST00000070418.4
Dclk1
doublecortin-like kinase 1
chr2_+_3114220 1.901 ENSMUST00000072955.5
Fam171a1
family with sequence similarity 171, member A1
chr19_+_40831248 1.841 ENSMUST00000025983.6
ENSMUST00000120057.1
Ccnj

cyclin J

chr11_-_78165521 1.827 ENSMUST00000017530.3
Traf4
TNF receptor associated factor 4
chr13_-_102905740 1.795 ENSMUST00000167462.1
Mast4
microtubule associated serine/threonine kinase family member 4
chr3_-_127837419 1.792 ENSMUST00000051737.6
Ap1ar
adaptor-related protein complex 1 associated regulatory protein
chr12_+_31265279 1.774 ENSMUST00000002979.8
ENSMUST00000170495.1
Lamb1

laminin B1

chr1_+_193173469 1.773 ENSMUST00000161235.1
ENSMUST00000110831.2
ENSMUST00000178744.1
A130010J15Rik


RIKEN cDNA A130010J15 gene


chr2_-_27426992 1.756 ENSMUST00000056176.7
Vav2
vav 2 oncogene
chr12_-_86726439 1.750 ENSMUST00000021682.8
Angel1
angel homolog 1 (Drosophila)
chr2_+_181763315 1.733 ENSMUST00000081125.4
Myt1
myelin transcription factor 1
chr1_+_134182150 1.713 ENSMUST00000156873.1
Chi3l1
chitinase 3-like 1
chr1_+_134182404 1.703 ENSMUST00000153856.1
ENSMUST00000082060.3
ENSMUST00000133701.1
ENSMUST00000132873.1
Chi3l1



chitinase 3-like 1



chr1_+_160906372 1.700 ENSMUST00000161609.1
Rc3h1
RING CCCH (C3H) domains 1
chr17_+_55445550 1.667 ENSMUST00000025000.3
St6gal2
beta galactoside alpha 2,6 sialyltransferase 2
chr14_-_72602945 1.655 ENSMUST00000162825.1
Fndc3a
fibronectin type III domain containing 3A
chr2_-_103797617 1.654 ENSMUST00000028607.6
Caprin1
cell cycle associated protein 1
chr12_-_54986363 1.635 ENSMUST00000173433.1
ENSMUST00000173803.1
Baz1a
Gm20403
bromodomain adjacent to zinc finger domain 1A
predicted gene 20403
chr15_+_99702278 1.631 ENSMUST00000023759.4
Smarcd1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
chr14_-_121698417 1.622 ENSMUST00000040700.7
Dock9
dedicator of cytokinesis 9
chr13_-_23745511 1.616 ENSMUST00000091752.2
Hist1h3c
histone cluster 1, H3c
chr12_+_31265234 1.604 ENSMUST00000169088.1
Lamb1
laminin B1
chr11_+_23256001 1.593 ENSMUST00000020538.6
ENSMUST00000109551.1
ENSMUST00000102870.1
ENSMUST00000102869.1
Xpo1



exportin 1, CRM1 homolog (yeast)



chr3_-_105052948 1.592 ENSMUST00000098763.2
Cttnbp2nl
CTTNBP2 N-terminal like
chr4_+_57434247 1.580 ENSMUST00000102905.1
Palm2
paralemmin 2
chr17_-_28486082 1.567 ENSMUST00000079413.3
Fkbp5
FK506 binding protein 5
chr2_+_104590453 1.561 ENSMUST00000028599.7
Cstf3
cleavage stimulation factor, 3' pre-RNA, subunit 3
chr4_+_59626189 1.560 ENSMUST00000070150.4
ENSMUST00000052420.6
E130308A19Rik

RIKEN cDNA E130308A19 gene

chr3_+_65109343 1.481 ENSMUST00000159525.1
ENSMUST00000049230.8
Kcnab1

potassium voltage-gated channel, shaker-related subfamily, beta member 1

chr6_-_50261743 1.460 ENSMUST00000101405.3
ENSMUST00000165099.1
ENSMUST00000170142.1
Dfna5


deafness, autosomal dominant 5 (human)


chr13_+_93304066 1.454 ENSMUST00000109493.1
Homer1
homer homolog 1 (Drosophila)
chrX_-_53269786 1.447 ENSMUST00000114841.1
ENSMUST00000071023.5
Fam122b

family with sequence similarity 122, member B

chr19_-_57118897 1.431 ENSMUST00000111526.1
Ablim1
actin-binding LIM protein 1
chr2_+_120476911 1.424 ENSMUST00000110716.1
ENSMUST00000028748.6
ENSMUST00000090028.5
ENSMUST00000110719.2
Capn3



calpain 3



chr9_-_60687459 1.420 ENSMUST00000114032.1
ENSMUST00000166168.1
ENSMUST00000132366.1
Lrrc49


leucine rich repeat containing 49


chr19_+_40831296 1.416 ENSMUST00000119316.1
Ccnj
cyclin J
chr2_+_119618717 1.403 ENSMUST00000028771.7
Nusap1
nucleolar and spindle associated protein 1
chr1_+_17727034 1.402 ENSMUST00000159958.1
ENSMUST00000160305.1
ENSMUST00000095075.4
Crispld1


cysteine-rich secretory protein LCCL domain containing 1


chr18_-_43393346 1.401 ENSMUST00000025379.7
Dpysl3
dihydropyrimidinase-like 3
chr5_-_142906702 1.345 ENSMUST00000167721.1
ENSMUST00000163829.1
ENSMUST00000100497.4
Actb


actin, beta


chr5_+_33995984 1.331 ENSMUST00000056355.8
Nat8l
N-acetyltransferase 8-like
chr5_-_50058908 1.324 ENSMUST00000030971.5
Gpr125
G protein-coupled receptor 125
chr17_-_80480435 1.274 ENSMUST00000068714.5
Sos1
son of sevenless homolog 1 (Drosophila)
chr19_-_4943049 1.274 ENSMUST00000133254.1
ENSMUST00000120475.1
ENSMUST00000025834.7
Peli3


pellino 3


chr5_-_8622855 1.271 ENSMUST00000047485.8
ENSMUST00000115378.1
Rundc3b

RUN domain containing 3B

chr9_+_98422961 1.264 ENSMUST00000052068.9
Rbp1
retinol binding protein 1, cellular
chr8_-_90348126 1.244 ENSMUST00000176034.1
ENSMUST00000176616.1
Tox3

TOX high mobility group box family member 3

chr4_+_127021311 1.243 ENSMUST00000030623.7
Sfpq
splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)
chr2_-_176917518 1.236 ENSMUST00000108931.2
Gm14296
predicted gene 14296
chr2_+_178141920 1.223 ENSMUST00000103066.3
Phactr3
phosphatase and actin regulator 3
chr10_-_117376922 1.216 ENSMUST00000177145.1
ENSMUST00000176670.1
Cpsf6

cleavage and polyadenylation specific factor 6

chr11_-_69672307 1.212 ENSMUST00000163666.2
Eif4a1
eukaryotic translation initiation factor 4A1
chr9_+_80066895 1.192 ENSMUST00000037484.8
ENSMUST00000176640.1
Senp6

SUMO/sentrin specific peptidase 6

chr19_-_57118981 1.184 ENSMUST00000111528.1
ENSMUST00000111529.1
ENSMUST00000104902.2
Ablim1


actin-binding LIM protein 1


chr11_-_76577701 1.177 ENSMUST00000176179.1
Abr
active BCR-related gene
chr9_-_60688118 1.170 ENSMUST00000114034.2
ENSMUST00000065603.5
Lrrc49

leucine rich repeat containing 49

chr2_+_176236860 1.159 ENSMUST00000166464.1
2210418O10Rik
RIKEN cDNA 2210418O10 gene
chr16_+_90386382 1.148 ENSMUST00000065856.6
Hunk
hormonally upregulated Neu-associated kinase
chrX_-_136993027 1.139 ENSMUST00000171738.1
ENSMUST00000056674.5
ENSMUST00000129807.1
Slc25a53


solute carrier family 25, member 53


chr8_+_22757744 1.129 ENSMUST00000033941.5
Plat
plasminogen activator, tissue
chr12_+_100110148 1.126 ENSMUST00000021595.8
Psmc1
protease (prosome, macropain) 26S subunit, ATPase 1
chr6_+_120364094 1.112 ENSMUST00000100996.3
ENSMUST00000005108.7
Kdm5a

lysine (K)-specific demethylase 5A

chr15_+_100038635 1.101 ENSMUST00000100203.3
Dip2b
DIP2 disco-interacting protein 2 homolog B (Drosophila)
chr6_-_29212240 1.098 ENSMUST00000160878.1
ENSMUST00000078155.5
Impdh1

inosine 5'-phosphate dehydrogenase 1

chr8_-_90348343 1.094 ENSMUST00000109621.3
Tox3
TOX high mobility group box family member 3
chr17_-_59013264 1.090 ENSMUST00000174122.1
ENSMUST00000025065.5
Nudt12

nudix (nucleoside diphosphate linked moiety X)-type motif 12

chr8_-_47713920 1.088 ENSMUST00000038738.5
Cdkn2aip
CDKN2A interacting protein
chr4_-_108833544 1.054 ENSMUST00000102740.1
ENSMUST00000102741.1
Btf3l4

basic transcription factor 3-like 4

chr16_+_94370786 1.047 ENSMUST00000147046.1
ENSMUST00000149885.1
ENSMUST00000127667.1
ENSMUST00000119131.1
ENSMUST00000145883.1
Ttc3




tetratricopeptide repeat domain 3




chr4_+_128727585 1.035 ENSMUST00000106079.3
ENSMUST00000133439.1
Phc2

polyhomeotic-like 2 (Drosophila)

chr10_+_45067167 1.034 ENSMUST00000099858.2
Prep
prolyl endopeptidase
chr2_-_132111440 1.017 ENSMUST00000128899.1
Slc23a2
solute carrier family 23 (nucleobase transporters), member 2
chr13_+_21716385 0.990 ENSMUST00000070124.3
Hist1h2ai
histone cluster 1, H2ai
chr10_-_125328957 0.988 ENSMUST00000063318.2
Slc16a7
solute carrier family 16 (monocarboxylic acid transporters), member 7
chr1_-_79761752 0.973 ENSMUST00000113512.1
ENSMUST00000113513.1
ENSMUST00000113515.1
ENSMUST00000113514.1
ENSMUST00000113510.1
ENSMUST00000113511.1
ENSMUST00000048820.7
Wdfy1






WD repeat and FYVE domain containing 1






chrX_+_98936314 0.969 ENSMUST00000113811.1
Yipf6
Yip1 domain family, member 6
chr4_-_132212060 0.967 ENSMUST00000085181.4
Ythdf2
YTH domain family 2
chr14_-_60197173 0.963 ENSMUST00000131670.1
Atp8a2
ATPase, aminophospholipid transporter-like, class I, type 8A, member 2
chr17_-_34121944 0.961 ENSMUST00000151986.1
Brd2
bromodomain containing 2
chr3_+_146500071 0.958 ENSMUST00000119130.1
Gng5
guanine nucleotide binding protein (G protein), gamma 5
chr4_-_129227883 0.952 ENSMUST00000106051.1
C77080
expressed sequence C77080
chr9_-_9239019 0.948 ENSMUST00000183182.1
Arhgap42
Rho GTPase activating protein 42
chr11_-_98022594 0.944 ENSMUST00000103144.3
ENSMUST00000017552.6
ENSMUST00000092736.4
ENSMUST00000107562.1
Cacnb1



calcium channel, voltage-dependent, beta 1 subunit



chr15_-_79328154 0.944 ENSMUST00000166977.2
Pla2g6
phospholipase A2, group VI
chr10_+_57486354 0.939 ENSMUST00000079833.4
Hsf2
heat shock factor 2
chr12_-_99883429 0.914 ENSMUST00000046485.3
Efcab11
EF-hand calcium binding domain 11
chr4_-_49593875 0.900 ENSMUST00000151542.1
Tmem246
transmembrane protein 246
chr1_+_17145357 0.886 ENSMUST00000026879.7
Gdap1
ganglioside-induced differentiation-associated-protein 1
chr7_+_64501687 0.884 ENSMUST00000032732.8
Apba2
amyloid beta (A4) precursor protein-binding, family A, member 2
chr7_+_64501949 0.874 ENSMUST00000138829.1
Apba2
amyloid beta (A4) precursor protein-binding, family A, member 2
chr11_+_23665615 0.854 ENSMUST00000109525.1
ENSMUST00000020520.4
Pus10

pseudouridylate synthase 10

chr11_+_105178765 0.849 ENSMUST00000106939.2
Tlk2
tousled-like kinase 2 (Arabidopsis)
chr15_-_79328201 0.837 ENSMUST00000173163.1
ENSMUST00000047816.8
ENSMUST00000172403.2
ENSMUST00000173632.1
Pla2g6



phospholipase A2, group VI



chr4_-_108833608 0.822 ENSMUST00000102742.4
Btf3l4
basic transcription factor 3-like 4
chr10_+_80300997 0.821 ENSMUST00000140828.1
ENSMUST00000138909.1
Apc2

adenomatosis polyposis coli 2

chr11_+_20201406 0.816 ENSMUST00000020358.5
ENSMUST00000109602.1
ENSMUST00000109601.1
Rab1


RAB1, member RAS oncogene family


chr2_-_85196697 0.807 ENSMUST00000099930.2
ENSMUST00000111601.1
Lrrc55

leucine rich repeat containing 55

chr9_-_13446753 0.805 ENSMUST00000167906.2
Gm17571
predicted gene, 17571
chr12_+_108605757 0.803 ENSMUST00000109854.2
Evl
Ena-vasodilator stimulated phosphoprotein
chr2_-_18048347 0.802 ENSMUST00000066885.5
Skida1
SKI/DACH domain containing 1
chr14_+_61138445 0.799 ENSMUST00000089394.3
ENSMUST00000119509.1
Sacs

sacsin

chr12_-_112829351 0.796 ENSMUST00000062092.5
Cdca4
cell division cycle associated 4
chr7_+_128688480 0.782 ENSMUST00000118605.1
Inpp5f
inositol polyphosphate-5-phosphatase F
chr2_-_34755229 0.781 ENSMUST00000102800.1
Gapvd1
GTPase activating protein and VPS9 domains 1
chr13_+_21810428 0.767 ENSMUST00000091745.5
Hist1h2ao
histone cluster 1, H2ao
chr3_+_90079540 0.766 ENSMUST00000029549.9
ENSMUST00000118566.1
ENSMUST00000119158.1
Tpm3


tropomyosin 3, gamma


chr4_-_6990774 0.766 ENSMUST00000039987.3
Tox
thymocyte selection-associated high mobility group box
chr16_-_96082389 0.765 ENSMUST00000099502.2
ENSMUST00000023631.8
ENSMUST00000113829.1
ENSMUST00000153398.1
Brwd1



bromodomain and WD repeat domain containing 1



chr6_-_42693087 0.764 ENSMUST00000121083.1
Fam115a
family with sequence similarity 115, member A
chr1_+_82839449 0.761 ENSMUST00000113444.1
ENSMUST00000063380.4
Agfg1

ArfGAP with FG repeats 1

chr1_+_153899937 0.756 ENSMUST00000086199.5
Glul
glutamate-ammonia ligase (glutamine synthetase)
chr17_-_70853482 0.755 ENSMUST00000118283.1
Tgif1
TGFB-induced factor homeobox 1
chr17_-_32284088 0.731 ENSMUST00000119123.1
ENSMUST00000003726.8
ENSMUST00000121285.1
ENSMUST00000120276.1
ENSMUST00000114475.2
Brd4




bromodomain containing 4




chr16_+_17144600 0.726 ENSMUST00000115702.1
Ydjc
YdjC homolog (bacterial)
chr19_-_37178011 0.725 ENSMUST00000133988.1
Cpeb3
cytoplasmic polyadenylation element binding protein 3
chrX_+_93654863 0.719 ENSMUST00000113933.2
Pcyt1b
phosphate cytidylyltransferase 1, choline, beta isoform
chr1_+_180101144 0.711 ENSMUST00000133890.1
Cdc42bpa
CDC42 binding protein kinase alpha
chr18_-_14682756 0.710 ENSMUST00000040964.6
ENSMUST00000092041.3
ENSMUST00000040924.7
Ss18


synovial sarcoma translocation, Chromosome 18


chr1_+_133045984 0.699 ENSMUST00000077730.5
Pik3c2b
phosphoinositide-3-kinase, class 2, beta polypeptide
chr2_-_181314500 0.695 ENSMUST00000103045.3
Stmn3
stathmin-like 3
chr12_-_108835845 0.677 ENSMUST00000021693.3
Slc25a29
solute carrier family 25 (mitochondrial carrier, palmitoylcarnitine transporter), member 29
chr2_-_7081256 0.674 ENSMUST00000183209.1
Celf2
CUGBP, Elav-like family member 2
chr7_-_105574324 0.667 ENSMUST00000081165.7
Apbb1
amyloid beta (A4) precursor protein-binding, family B, member 1
chr4_-_136602641 0.657 ENSMUST00000105847.1
ENSMUST00000116273.2
Kdm1a

lysine (K)-specific demethylase 1A

chr2_+_102706356 0.654 ENSMUST00000123759.1
ENSMUST00000111212.1
ENSMUST00000005220.4
Slc1a2


solute carrier family 1 (glial high affinity glutamate transporter), member 2


chr10_+_80151154 0.650 ENSMUST00000146516.1
ENSMUST00000144526.1
Midn

midnolin

chr10_-_37138863 0.649 ENSMUST00000092584.5
Marcks
myristoylated alanine rich protein kinase C substrate
chr11_-_90638062 0.642 ENSMUST00000020858.7
ENSMUST00000107875.1
ENSMUST00000107872.1
ENSMUST00000143203.1
Stxbp4



syntaxin binding protein 4



chr16_-_17144415 0.640 ENSMUST00000115709.1
Ccdc116
coiled-coil domain containing 116
chr4_-_129440800 0.636 ENSMUST00000053042.5
ENSMUST00000106046.1
Zbtb8b

zinc finger and BTB domain containing 8b

chrX_+_101429555 0.632 ENSMUST00000033673.6
Nono
non-POU-domain-containing, octamer binding protein

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 17.6 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
1.6 4.9 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
1.3 4.0 GO:0030070 insulin processing(GO:0030070)
1.1 5.4 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
1.0 3.1 GO:0015772 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
1.0 27.9 GO:0008340 determination of adult lifespan(GO:0008340)
1.0 5.8 GO:0070294 renal sodium ion absorption(GO:0070294)
0.9 2.6 GO:1904339 negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.8 3.4 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.8 4.0 GO:0019230 proprioception(GO:0019230)
0.6 0.6 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.6 3.0 GO:1901526 negative regulation of mitochondrial membrane permeability(GO:0035795) positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.6 4.6 GO:0010944 negative regulation of transcription by competitive promoter binding(GO:0010944)
0.5 6.0 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.5 3.2 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
0.5 7.5 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.5 4.9 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.5 6.2 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.5 4.7 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.5 1.4 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.4 1.3 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.4 1.8 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.4 1.8 GO:0090238 positive regulation of arachidonic acid secretion(GO:0090238)
0.4 1.3 GO:0070428 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428) regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070432)
0.3 2.4 GO:0051461 protein import into peroxisome matrix, docking(GO:0016560) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.3 3.1 GO:0070874 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.3 1.0 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.3 2.0 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.3 1.3 GO:0051582 positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.3 3.0 GO:0001842 neural fold formation(GO:0001842)
0.3 1.6 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
0.3 1.3 GO:0006776 vitamin A metabolic process(GO:0006776)
0.3 1.6 GO:1904690 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
0.3 4.1 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.3 2.1 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.3 3.3 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.3 1.1 GO:0006742 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.3 1.8 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.3 0.8 GO:0019676 ammonia assimilation cycle(GO:0019676)
0.2 1.0 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.2 0.7 GO:0002182 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.2 0.9 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.2 5.4 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.2 0.7 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.2 1.1 GO:0060279 positive regulation of ovulation(GO:0060279)
0.2 0.7 GO:1902022 L-lysine transport(GO:1902022)
0.2 2.5 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.2 1.1 GO:0006177 GMP biosynthetic process(GO:0006177)
0.2 1.2 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.2 0.8 GO:0031161 phosphatidylinositol catabolic process(GO:0031161)
0.2 1.3 GO:0007296 vitellogenesis(GO:0007296)
0.2 0.4 GO:0071211 protein targeting to vacuole involved in autophagy(GO:0071211)
0.2 1.6 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.2 0.7 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.2 0.3 GO:1903898 negative regulation of PERK-mediated unfolded protein response(GO:1903898)
0.2 1.2 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.2 1.8 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.2 1.0 GO:0034145 positive regulation of toll-like receptor 4 signaling pathway(GO:0034145)
0.2 0.5 GO:0003349 epicardium-derived cardiac endothelial cell differentiation(GO:0003349)
0.2 1.0 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.2 0.6 GO:0010838 positive regulation of keratinocyte proliferation(GO:0010838)
0.2 1.0 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.2 0.5 GO:1904154 trimming of terminal mannose on B branch(GO:0036509) positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.2 1.7 GO:0060539 diaphragm development(GO:0060539)
0.2 4.0 GO:0007340 acrosome reaction(GO:0007340)
0.1 7.7 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.1 1.0 GO:0061092 involuntary skeletal muscle contraction(GO:0003011) regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.1 0.8 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.1 0.7 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.1 0.6 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.1 0.7 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1 1.6 GO:0006337 nucleosome disassembly(GO:0006337)
0.1 0.4 GO:2000484 transformation of host cell by virus(GO:0019087) positive regulation of interleukin-8 secretion(GO:2000484)
0.1 0.7 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.1 1.5 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.1 1.1 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.1 1.4 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.1 0.5 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 0.9 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.1 0.6 GO:0032274 gonadotropin secretion(GO:0032274)
0.1 2.4 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 14.0 GO:0008360 regulation of cell shape(GO:0008360)
0.1 0.8 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.1 3.4 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.1 0.6 GO:0051764 actin crosslink formation(GO:0051764)
0.1 1.7 GO:0060009 Sertoli cell development(GO:0060009)
0.1 3.9 GO:0032410 negative regulation of transporter activity(GO:0032410)
0.1 1.6 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.1 0.4 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.1 4.5 GO:0070613 regulation of protein processing(GO:0070613)
0.1 0.8 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.1 0.8 GO:0001675 acrosome assembly(GO:0001675)
0.1 0.6 GO:0006968 cellular defense response(GO:0006968)
0.1 0.2 GO:0070197 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.1 2.7 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.1 1.6 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 2.0 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.1 0.2 GO:0010626 negative regulation of Schwann cell proliferation(GO:0010626)
0.1 0.5 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.1 0.8 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1 0.1 GO:1903756 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.1 0.3 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.1 0.4 GO:1902669 positive regulation of axon guidance(GO:1902669)
0.1 0.2 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.1 1.4 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.1 0.4 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.1 0.6 GO:0030238 male sex determination(GO:0030238)
0.1 2.4 GO:0030317 sperm motility(GO:0030317)
0.0 0.8 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 1.5 GO:0006378 mRNA polyadenylation(GO:0006378)
0.0 0.9 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 1.6 GO:0006379 mRNA cleavage(GO:0006379)
0.0 1.4 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.9 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.2 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.0 0.7 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 1.5 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.3 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0 1.7 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0 0.4 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 4.3 GO:0048675 axon extension(GO:0048675)
0.0 0.2 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 1.5 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.0 1.7 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 1.2 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 1.2 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 3.6 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.0 4.2 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.0 0.1 GO:0048318 axial mesoderm development(GO:0048318)
0.0 0.3 GO:0021794 thalamus development(GO:0021794)
0.0 2.3 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 1.8 GO:0006342 chromatin silencing(GO:0006342)
0.0 0.7 GO:0045739 positive regulation of DNA repair(GO:0045739)
0.0 0.4 GO:0015858 nucleoside transport(GO:0015858)
0.0 0.1 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.0 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.5 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.1 GO:0006868 glutamine transport(GO:0006868)
0.0 0.6 GO:0006839 mitochondrial transport(GO:0006839)
0.0 2.8 GO:0019221 cytokine-mediated signaling pathway(GO:0019221)
0.0 0.6 GO:0043113 receptor clustering(GO:0043113)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.6 GO:0008623 CHRAC(GO:0008623)
0.8 3.4 GO:0043259 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259)
0.7 3.0 GO:0090537 CERF complex(GO:0090537)
0.6 2.4 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.4 3.4 GO:0042382 paraspeckles(GO:0042382)
0.3 4.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.3 1.0 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.2 6.2 GO:0000930 gamma-tubulin complex(GO:0000930)
0.2 5.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.2 1.1 GO:0001652 granular component(GO:0001652)
0.2 0.6 GO:0042585 germinal vesicle(GO:0042585)
0.2 3.6 GO:0035102 PRC1 complex(GO:0035102)
0.2 7.5 GO:0043034 costamere(GO:0043034)
0.1 1.6 GO:0005642 annulate lamellae(GO:0005642)
0.1 1.1 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1 0.7 GO:1990761 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.1 2.3 GO:0071564 npBAF complex(GO:0071564)
0.1 0.4 GO:0031533 mRNA cap methyltransferase complex(GO:0031533)
0.1 2.0 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 1.5 GO:1990635 proximal dendrite(GO:1990635)
0.1 1.1 GO:0031595 nuclear proteasome complex(GO:0031595)
0.1 0.6 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 0.4 GO:0043202 lysosomal lumen(GO:0043202)
0.1 5.8 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 0.7 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 12.6 GO:0005884 actin filament(GO:0005884)
0.1 7.8 GO:0016363 nuclear matrix(GO:0016363)
0.1 0.7 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.1 5.9 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 7.6 GO:0043204 perikaryon(GO:0043204)
0.1 4.0 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 0.3 GO:0097443 sorting endosome(GO:0097443) cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.1 1.3 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.1 2.2 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 2.7 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.4 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 3.3 GO:0042641 actomyosin(GO:0042641)
0.0 0.6 GO:0010369 chromocenter(GO:0010369)
0.0 0.8 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.9 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.9 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.5 GO:0090544 BAF-type complex(GO:0090544)
0.0 0.7 GO:0030673 axolemma(GO:0030673)
0.0 4.8 GO:0014069 postsynaptic density(GO:0014069)
0.0 0.5 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.4 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.5 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.2 GO:1990909 Wnt signalosome(GO:1990909)
0.0 1.0 GO:0009925 basal plasma membrane(GO:0009925)
0.0 3.4 GO:0001650 fibrillar center(GO:0001650)
0.0 6.1 GO:0015629 actin cytoskeleton(GO:0015629)
0.0 0.5 GO:0005882 intermediate filament(GO:0005882)
0.0 65.4 GO:0005829 cytosol(GO:0005829)
0.0 0.7 GO:1990391 DNA repair complex(GO:1990391)
0.0 0.2 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 1.1 GO:0030141 secretory granule(GO:0030141)
0.0 0.8 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 2.4 GO:0030133 transport vesicle(GO:0030133)
0.0 0.5 GO:0036126 sperm flagellum(GO:0036126)
0.0 0.2 GO:0000407 pre-autophagosomal structure(GO:0000407)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 GO:0008515 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.7 7.5 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.6 3.0 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.6 1.8 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.6 4.6 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.5 2.4 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.5 2.4 GO:0005113 patched binding(GO:0005113)
0.4 1.3 GO:0098973 structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.4 3.4 GO:0043208 glycosphingolipid binding(GO:0043208)
0.4 4.3 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.4 4.1 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.4 1.8 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.3 1.0 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.3 2.3 GO:0034056 estrogen response element binding(GO:0034056)
0.3 2.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.3 1.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.3 1.1 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.3 0.8 GO:0016880 acid-ammonia (or amide) ligase activity(GO:0016880)
0.2 1.0 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.2 2.0 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.2 0.7 GO:0034211 GTP-dependent protein kinase activity(GO:0034211)
0.2 1.3 GO:0019841 retinol binding(GO:0019841)
0.2 3.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.2 6.2 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.2 1.8 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.2 1.4 GO:0031432 titin binding(GO:0031432)
0.2 9.7 GO:0001784 phosphotyrosine binding(GO:0001784)
0.2 4.9 GO:0003785 actin monomer binding(GO:0003785)
0.2 3.9 GO:0070064 proline-rich region binding(GO:0070064)
0.2 1.1 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.2 1.6 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.2 1.6 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.2 0.8 GO:0052833 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.2 1.4 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.2 1.8 GO:0031996 thioesterase binding(GO:0031996)
0.2 3.3 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 1.7 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 0.7 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 0.6 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.1 0.7 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.1 0.4 GO:0031686 A1 adenosine receptor binding(GO:0031686)
0.1 0.4 GO:0004482 mRNA (guanine-N7-)-methyltransferase activity(GO:0004482)
0.1 0.7 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 6.3 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 2.4 GO:0035613 RNA stem-loop binding(GO:0035613)
0.1 7.4 GO:0035064 methylated histone binding(GO:0035064)
0.1 4.3 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.1 6.6 GO:0005080 protein kinase C binding(GO:0005080)
0.1 1.0 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.1 1.5 GO:0070402 aldo-keto reductase (NADP) activity(GO:0004033) NADPH binding(GO:0070402)
0.1 1.2 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.1 0.9 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 4.0 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 15.9 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 1.0 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 1.6 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 0.7 GO:0001727 lipid kinase activity(GO:0001727)
0.1 0.2 GO:0004816 asparagine-tRNA ligase activity(GO:0004816)
0.1 0.8 GO:0005522 profilin binding(GO:0005522)
0.1 5.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 10.4 GO:0051015 actin filament binding(GO:0051015)
0.1 0.4 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.1 0.2 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.1 0.5 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 1.0 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 0.5 GO:0050733 RS domain binding(GO:0050733)
0.1 0.9 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 3.0 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.2 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.0 1.0 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 1.0 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.4 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.6 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.8 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 16.2 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.1 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.0 3.1 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 1.1 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 0.2 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 1.3 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.9 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.6 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 1.6 GO:0004004 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.0 7.2 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 1.3 GO:0002039 p53 binding(GO:0002039)
0.0 3.1 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.2 GO:0043495 protein anchor(GO:0043495)
0.0 1.6 GO:0032947 protein complex scaffold(GO:0032947)
0.0 3.3 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 1.3 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.0 0.4 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.2 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 1.6 GO:0042393 histone binding(GO:0042393)
0.0 0.1 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.9 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 0.8 GO:0008013 beta-catenin binding(GO:0008013)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.4 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.2 8.4 SA_PTEN_PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.2 3.0 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 4.9 PID_CD40_PATHWAY CD40/CD40L signaling
0.1 2.2 SA_B_CELL_RECEPTOR_COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 3.3 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.1 3.8 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.1 1.3 PID_RETINOIC_ACID_PATHWAY Retinoic acid receptors-mediated signaling
0.1 3.4 PID_IGF1_PATHWAY IGF1 pathway
0.1 2.4 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.1 1.6 PID_RANBP2_PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 1.1 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.1 6.0 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.0 3.4 PID_REG_GR_PATHWAY Glucocorticoid receptor regulatory network
0.0 1.1 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.0 0.8 ST_TUMOR_NECROSIS_FACTOR_PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.6 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.0 0.7 SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES Genes related to the insulin receptor pathway
0.0 2.1 PID_TGFBR_PATHWAY TGF-beta receptor signaling
0.0 1.0 PID_RB_1PATHWAY Regulation of retinoblastoma protein
0.0 1.6 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity
0.0 0.7 PID_KIT_PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 1.4 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.0 0.6 PID_IL4_2PATHWAY IL4-mediated signaling events
0.0 0.6 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.9 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.2 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.4 WNT_SIGNALING Genes related to Wnt-mediated signal transduction

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 10.5 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.2 3.3 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.2 5.4 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.2 4.3 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.2 4.9 REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.2 4.0 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 1.9 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.1 1.8 REACTOME_ACYL_CHAIN_REMODELLING_OF_PC Genes involved in Acyl chain remodelling of PC
0.1 2.6 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.1 3.2 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 1.3 REACTOME_IRAK1_RECRUITS_IKK_COMPLEX Genes involved in IRAK1 recruits IKK complex
0.1 1.6 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 1.4 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 1.6 REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.1 0.6 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 1.1 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 0.4 REACTOME_DESTABILIZATION_OF_MRNA_BY_AUF1_HNRNP_D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.1 1.9 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 3.0 REACTOME_GLUCOSE_TRANSPORT Genes involved in Glucose transport
0.1 0.4 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 1.7 REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.1 0.8 REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES Genes involved in Generation of second messenger molecules
0.0 1.2 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.0 0.6 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.0 0.9 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 1.5 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.0 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.3 REACTOME_REGULATION_OF_IFNG_SIGNALING Genes involved in Regulation of IFNG signaling
0.0 1.7 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.7 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.7 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.0 3.4 REACTOME_L1CAM_INTERACTIONS Genes involved in L1CAM interactions
0.0 0.8 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 1.0 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 6.0 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.6 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.5 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.0 1.0 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 1.0 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 1.2 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.0 0.4 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.8 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.4 REACTOME_MRNA_CAPPING Genes involved in mRNA Capping
0.0 1.2 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 1.8 REACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES Genes involved in Transmission across Chemical Synapses
0.0 1.2 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production