Motif ID: Sox15

Z-value: 0.560


Transcription factors associated with Sox15:

Gene SymbolEntrez IDGene Name
Sox15 ENSMUSG00000041287.5 Sox15



Activity profile for motif Sox15.

activity profile for motif Sox15


Sorted Z-values histogram for motif Sox15

Sorted Z-values for motif Sox15



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox15

PNG image of the network

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Top targets:


Showing 1 to 20 of 120 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_-_119238794 4.657 ENSMUST00000026360.8
 Itgb8
integrin beta 8
chr17_+_55445550 4.123 ENSMUST00000025000.3
 St6gal2
beta galactoside alpha 2,6 sialyltransferase 2
chr3_-_8964037 3.540 ENSMUST00000091354.5
ENSMUST00000094381.4
 Tpd52

tumor protein D52

chr6_+_17491216 3.373 ENSMUST00000080469.5
 Met
met proto-oncogene
chr6_+_17463927 2.996 ENSMUST00000115442.1
 Met
met proto-oncogene
chr6_+_17463749 2.674 ENSMUST00000115443.1
 Met
met proto-oncogene
chr2_-_65567505 2.626 ENSMUST00000100069.2
 Scn3a
sodium channel, voltage-gated, type III, alpha
chr2_-_65567465 2.598 ENSMUST00000066432.5
 Scn3a
sodium channel, voltage-gated, type III, alpha
chr6_+_17463826 2.535 ENSMUST00000140070.1
 Met
met proto-oncogene
chr5_+_148265202 2.458 ENSMUST00000110515.2
 Mtus2
microtubule associated tumor suppressor candidate 2
chr6_-_23248264 2.442 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr5_+_148265307 2.234 ENSMUST00000110514.1
 Mtus2
microtubule associated tumor suppressor candidate 2
chr3_+_31902666 1.985 ENSMUST00000119970.1
ENSMUST00000178668.1
 Kcnmb2

potassium large conductance calcium-activated channel, subfamily M, beta member 2

chr5_+_148265265 1.933 ENSMUST00000071878.5
 Mtus2
microtubule associated tumor suppressor candidate 2
chr8_-_11312731 1.768 ENSMUST00000033898.9
 Col4a1
collagen, type IV, alpha 1
chr6_+_125552948 1.649 ENSMUST00000112254.1
ENSMUST00000112253.1
ENSMUST00000001995.7
 Vwf


Von Willebrand factor homolog


chr9_-_75597643 1.637 ENSMUST00000164100.1
 Tmod2
tropomodulin 2
chr18_+_33464163 1.471 ENSMUST00000097634.3
 Gm10549
predicted gene 10549
chr16_+_17146937 1.384 ENSMUST00000115706.1
ENSMUST00000069064.4
 Ydjc

YdjC homolog (bacterial)

chr3_-_33082004 1.340 ENSMUST00000108225.3
 Pex5l
peroxisomal biogenesis factor 5-like

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 55 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.7 11.6 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
1.0 5.2 GO:0046684 response to pyrethroid(GO:0046684)
0.3 4.7 GO:0001573 ganglioside metabolic process(GO:0001573)
0.2 4.1 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.2 2.5 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.1 2.5 GO:0006376 mRNA splice site selection(GO:0006376)
0.4 2.4 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.3 2.3 GO:0005513 detection of calcium ion(GO:0005513)
0.0 2.2 GO:0031032 actomyosin structure organization(GO:0031032)
0.3 1.8 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.2 1.7 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.3 1.6 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 1.6 GO:0030168 platelet activation(GO:0030168)
0.1 1.4 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.3 1.3 GO:0050904 diapedesis(GO:0050904)
0.3 1.3 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.2 1.3 GO:0051461 protein import into peroxisome matrix, docking(GO:0016560) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.1 1.3 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0 1.3 GO:0006970 response to osmotic stress(GO:0006970)
0.2 1.2 GO:0098909 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 29 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 11.5 GO:0009925 basal plasma membrane(GO:0009925)
0.1 6.6 GO:0045171 intercellular bridge(GO:0045171)
0.3 5.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.2 4.7 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 4.1 GO:0000139 Golgi membrane(GO:0000139)
0.0 2.3 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.4 1.8 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.3 1.6 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 1.6 GO:0005865 striated muscle thin filament(GO:0005865)
0.2 1.4 GO:0097165 nuclear stress granule(GO:0097165)
0.3 1.3 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.3 1.3 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 1.3 GO:0032420 stereocilium(GO:0032420)
0.1 1.2 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 1.2 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 1.2 GO:0005923 bicellular tight junction(GO:0005923)
0.1 1.1 GO:0032426 stereocilium tip(GO:0032426)
0.1 0.9 GO:0033269 internode region of axon(GO:0033269)
0.2 0.7 GO:0042585 germinal vesicle(GO:0042585)
0.1 0.7 GO:0044530 supraspliceosomal complex(GO:0044530)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 39 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.9 11.6 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.3 5.2 GO:0031402 sodium ion binding(GO:0031402)
0.7 4.7 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 4.7 GO:0008017 microtubule binding(GO:0008017)
0.8 4.1 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.1 2.3 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 1.8 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 1.8 GO:0036002 pre-mRNA binding(GO:0036002)
0.1 1.7 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.2 1.6 GO:0005523 tropomyosin binding(GO:0005523)
0.2 1.6 GO:0019865 immunoglobulin binding(GO:0019865)
0.0 1.4 GO:0017091 AU-rich element binding(GO:0017091)
0.3 1.3 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 1.3 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 1.3 GO:0019903 protein phosphatase binding(GO:0019903)
0.2 1.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 1.2 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 1.1 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 1.0 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 0.9 GO:0019911 structural constituent of myelin sheath(GO:0019911)

Gene overrepresentation in C2:CP category:

Showing 1 to 9 of 9 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 11.6 PID_ARF6_PATHWAY Arf6 signaling events
0.3 4.7 PID_INTEGRIN_CS_PATHWAY Integrin family cell surface interactions
0.1 3.1 PID_INTEGRIN3_PATHWAY Beta3 integrin cell surface interactions
0.0 2.9 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.0 1.7 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events
0.0 1.0 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.9 PID_P38_ALPHA_BETA_PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.8 PID_ER_NONGENOMIC_PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.5 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 14 of 14 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 10.8 REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING Genes involved in Sema4D in semaphorin signaling
0.1 7.7 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 3.5 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.1 2.3 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.2 1.9 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.0 1.3 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 1.2 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 0.9 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.1 0.8 REACTOME_FGFR1_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 0.8 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.1 0.7 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.5 REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.3 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.1 REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM Genes involved in Abacavir transport and metabolism