Motif ID: Sox2
Z-value: 3.633
Transcription factors associated with Sox2:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Sox2 | ENSMUSG00000074637.4 | Sox2 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Sox2 | mm10_v2_chr3_+_34649987_34650005 | 0.53 | 6.2e-07 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 33.1 | 99.4 | GO:0002302 | CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302) |
| 17.3 | 17.3 | GO:0009786 | regulation of asymmetric cell division(GO:0009786) |
| 15.9 | 175.1 | GO:2000741 | positive regulation of mesenchymal stem cell differentiation(GO:2000741) |
| 15.0 | 45.0 | GO:0003349 | epicardium-derived cardiac endothelial cell differentiation(GO:0003349) |
| 13.4 | 67.0 | GO:0035262 | gonad morphogenesis(GO:0035262) |
| 11.7 | 140.8 | GO:2001269 | positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269) |
| 11.4 | 136.9 | GO:0061302 | smooth muscle cell-matrix adhesion(GO:0061302) |
| 11.1 | 44.4 | GO:0090235 | regulation of metaphase plate congression(GO:0090235) |
| 10.3 | 20.7 | GO:0060023 | soft palate development(GO:0060023) |
| 9.4 | 37.6 | GO:0072137 | condensed mesenchymal cell proliferation(GO:0072137) |
| 9.3 | 28.0 | GO:0072139 | glomerular parietal epithelial cell differentiation(GO:0072139) |
| 9.3 | 18.6 | GO:0030220 | platelet formation(GO:0030220) |
| 9.1 | 54.8 | GO:1903300 | negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300) |
| 9.0 | 27.1 | GO:0006546 | glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464) |
| 8.8 | 97.2 | GO:0060539 | diaphragm development(GO:0060539) |
| 8.8 | 26.4 | GO:0001869 | regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869) |
| 8.6 | 25.8 | GO:0061153 | trachea submucosa development(GO:0061152) trachea gland development(GO:0061153) odontoblast differentiation(GO:0071895) regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899) |
| 8.4 | 134.4 | GO:0048387 | negative regulation of retinoic acid receptor signaling pathway(GO:0048387) |
| 8.2 | 32.6 | GO:0061113 | pancreas morphogenesis(GO:0061113) |
| 7.5 | 30.2 | GO:0003357 | noradrenergic neuron differentiation(GO:0003357) |
| 7.5 | 165.6 | GO:0048368 | lateral mesoderm development(GO:0048368) |
| 7.0 | 35.2 | GO:0045163 | clustering of voltage-gated potassium channels(GO:0045163) |
| 6.9 | 20.6 | GO:0060729 | intestinal epithelial structure maintenance(GO:0060729) |
| 6.8 | 34.2 | GO:0035426 | extracellular matrix-cell signaling(GO:0035426) |
| 6.7 | 40.4 | GO:0003383 | apical constriction(GO:0003383) |
| 6.2 | 18.6 | GO:0060364 | frontal suture morphogenesis(GO:0060364) |
| 6.2 | 43.2 | GO:0038092 | nodal signaling pathway(GO:0038092) |
| 5.9 | 35.3 | GO:0021797 | forebrain anterior/posterior pattern specification(GO:0021797) |
| 5.9 | 5.9 | GO:0090083 | regulation of inclusion body assembly(GO:0090083) |
| 5.8 | 35.0 | GO:0071699 | olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699) |
| 5.7 | 28.5 | GO:0070934 | CRD-mediated mRNA stabilization(GO:0070934) |
| 5.7 | 28.3 | GO:0006447 | regulation of translational initiation by iron(GO:0006447) positive regulation of translational initiation by iron(GO:0045994) |
| 5.6 | 28.2 | GO:0031022 | nuclear migration along microfilament(GO:0031022) |
| 5.6 | 16.9 | GO:1900133 | renin secretion into blood stream(GO:0002001) regulation of renin secretion into blood stream(GO:1900133) |
| 5.6 | 22.4 | GO:0043973 | histone H3-K4 acetylation(GO:0043973) |
| 5.5 | 22.0 | GO:1900220 | semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220) |
| 5.5 | 5.5 | GO:1904412 | regulation of cardiac ventricle development(GO:1904412) |
| 5.5 | 21.9 | GO:1990086 | lens fiber cell apoptotic process(GO:1990086) |
| 5.5 | 65.5 | GO:0035881 | amacrine cell differentiation(GO:0035881) |
| 5.1 | 20.6 | GO:0021603 | cranial nerve formation(GO:0021603) |
| 5.1 | 10.2 | GO:0048319 | axial mesoderm morphogenesis(GO:0048319) |
| 5.1 | 10.1 | GO:0086053 | AV node cell to bundle of His cell communication by electrical coupling(GO:0086053) |
| 5.0 | 20.1 | GO:0060316 | positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316) |
| 5.0 | 20.0 | GO:0060857 | establishment of glial blood-brain barrier(GO:0060857) |
| 4.9 | 9.8 | GO:2000620 | positive regulation of histone H4-K16 acetylation(GO:2000620) |
| 4.7 | 23.5 | GO:1904672 | regulation of somatic stem cell population maintenance(GO:1904672) |
| 4.4 | 21.8 | GO:0072513 | positive regulation of secondary heart field cardioblast proliferation(GO:0072513) |
| 4.4 | 13.1 | GO:0001757 | somite specification(GO:0001757) arterial endothelial cell fate commitment(GO:0060844) blood vessel endothelial cell fate commitment(GO:0060846) endothelial cell fate specification(GO:0060847) Notch signaling pathway involved in arterial endothelial cell fate commitment(GO:0060853) blood vessel endothelial cell fate specification(GO:0097101) |
| 4.4 | 65.5 | GO:0021521 | ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573) |
| 4.4 | 26.2 | GO:0072697 | protein localization to cell cortex(GO:0072697) |
| 4.3 | 17.4 | GO:0010838 | positive regulation of keratinocyte proliferation(GO:0010838) |
| 4.3 | 12.9 | GO:0046552 | eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552) |
| 4.3 | 12.9 | GO:0097089 | methyl-branched fatty acid metabolic process(GO:0097089) |
| 4.1 | 28.6 | GO:1903715 | regulation of aerobic respiration(GO:1903715) |
| 4.1 | 20.3 | GO:0018242 | protein O-linked glycosylation via serine(GO:0018242) |
| 4.0 | 12.1 | GO:1904059 | regulation of locomotor rhythm(GO:1904059) |
| 4.0 | 16.0 | GO:0006547 | histidine metabolic process(GO:0006547) |
| 4.0 | 15.8 | GO:1903760 | regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760) regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905024) |
| 4.0 | 83.0 | GO:0002089 | lens morphogenesis in camera-type eye(GO:0002089) |
| 3.8 | 46.2 | GO:0070933 | histone H4 deacetylation(GO:0070933) |
| 3.8 | 11.5 | GO:1904347 | intestine smooth muscle contraction(GO:0014827) regulation of gastro-intestinal system smooth muscle contraction(GO:1904304) regulation of small intestine smooth muscle contraction(GO:1904347) small intestine smooth muscle contraction(GO:1990770) |
| 3.8 | 11.5 | GO:0007403 | glial cell fate determination(GO:0007403) |
| 3.8 | 11.4 | GO:0030862 | neuroblast division in subventricular zone(GO:0021849) positive regulation of polarized epithelial cell differentiation(GO:0030862) |
| 3.8 | 15.2 | GO:0010288 | response to lead ion(GO:0010288) |
| 3.6 | 21.8 | GO:0002326 | B cell lineage commitment(GO:0002326) |
| 3.6 | 14.5 | GO:0038027 | apolipoprotein A-I-mediated signaling pathway(GO:0038027) |
| 3.6 | 7.2 | GO:0061511 | centriole elongation(GO:0061511) |
| 3.5 | 14.2 | GO:0070307 | lens fiber cell development(GO:0070307) |
| 3.5 | 28.2 | GO:0071802 | negative regulation of podosome assembly(GO:0071802) |
| 3.5 | 17.5 | GO:1903756 | regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758) |
| 3.5 | 27.9 | GO:1990845 | adaptive thermogenesis(GO:1990845) |
| 3.5 | 13.9 | GO:2001045 | response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681) negative regulation of integrin-mediated signaling pathway(GO:2001045) |
| 3.5 | 10.4 | GO:0021649 | vestibulocochlear nerve morphogenesis(GO:0021648) vestibulocochlear nerve structural organization(GO:0021649) ganglion morphogenesis(GO:0061552) dorsal root ganglion morphogenesis(GO:1904835) dorsal root ganglion development(GO:1990791) |
| 3.4 | 20.6 | GO:1903755 | regulation of SUMO transferase activity(GO:1903182) positive regulation of SUMO transferase activity(GO:1903755) |
| 3.3 | 13.4 | GO:0000415 | negative regulation of histone H3-K36 methylation(GO:0000415) |
| 3.2 | 6.4 | GO:0030240 | skeletal muscle thin filament assembly(GO:0030240) |
| 3.2 | 9.6 | GO:0060392 | negative regulation of SMAD protein import into nucleus(GO:0060392) |
| 3.2 | 25.3 | GO:0035542 | regulation of SNARE complex assembly(GO:0035542) |
| 3.2 | 15.8 | GO:0034162 | toll-like receptor 9 signaling pathway(GO:0034162) |
| 3.1 | 12.6 | GO:0055071 | cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071) |
| 3.1 | 12.5 | GO:0033326 | cerebrospinal fluid secretion(GO:0033326) |
| 3.1 | 15.4 | GO:0042117 | monocyte activation(GO:0042117) positive regulation of interleukin-8 secretion(GO:2000484) |
| 2.9 | 11.7 | GO:2000795 | negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795) |
| 2.9 | 14.6 | GO:0046666 | retinal cell programmed cell death(GO:0046666) |
| 2.9 | 14.4 | GO:0046208 | spermine catabolic process(GO:0046208) |
| 2.9 | 48.9 | GO:0071850 | mitotic cell cycle arrest(GO:0071850) |
| 2.9 | 8.6 | GO:0021972 | corticospinal neuron axon guidance through spinal cord(GO:0021972) positive regulation of negative chemotaxis(GO:0050924) induction of negative chemotaxis(GO:0050929) negative regulation of mononuclear cell migration(GO:0071676) negative regulation of retinal ganglion cell axon guidance(GO:0090260) |
| 2.8 | 14.1 | GO:0015671 | oxygen transport(GO:0015671) |
| 2.8 | 19.7 | GO:0010908 | regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) |
| 2.8 | 14.0 | GO:0010792 | blastocyst hatching(GO:0001835) DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) hatching(GO:0035188) organism emergence from protective structure(GO:0071684) |
| 2.8 | 8.3 | GO:2000048 | negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048) |
| 2.8 | 8.3 | GO:0098974 | postsynaptic actin cytoskeleton organization(GO:0098974) |
| 2.7 | 48.7 | GO:0009263 | deoxyribonucleotide biosynthetic process(GO:0009263) |
| 2.7 | 8.1 | GO:0021691 | cerebellar Purkinje cell layer maturation(GO:0021691) |
| 2.7 | 10.7 | GO:1903265 | positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265) |
| 2.6 | 18.5 | GO:0060836 | lymphatic endothelial cell differentiation(GO:0060836) |
| 2.6 | 13.2 | GO:0045578 | negative regulation of B cell differentiation(GO:0045578) |
| 2.6 | 10.6 | GO:0018076 | N-terminal peptidyl-lysine acetylation(GO:0018076) |
| 2.5 | 7.6 | GO:0042097 | interleukin-4 biosynthetic process(GO:0042097) regulation of interleukin-4 biosynthetic process(GO:0045402) antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007) |
| 2.4 | 12.2 | GO:0061086 | negative regulation of histone H3-K27 methylation(GO:0061086) |
| 2.4 | 17.0 | GO:0033227 | dsRNA transport(GO:0033227) |
| 2.4 | 7.3 | GO:2000616 | negative regulation of histone H3-K9 acetylation(GO:2000616) |
| 2.4 | 4.8 | GO:0009446 | putrescine biosynthetic process(GO:0009446) |
| 2.4 | 26.4 | GO:0035988 | chondrocyte proliferation(GO:0035988) |
| 2.4 | 7.1 | GO:0007525 | somatic muscle development(GO:0007525) |
| 2.3 | 18.3 | GO:0090074 | negative regulation of protein homodimerization activity(GO:0090074) |
| 2.2 | 22.4 | GO:0021869 | forebrain ventricular zone progenitor cell division(GO:0021869) |
| 2.2 | 6.6 | GO:0045819 | plasmacytoid dendritic cell activation(GO:0002270) positive regulation of glycogen catabolic process(GO:0045819) |
| 2.2 | 21.6 | GO:0016127 | cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127) |
| 2.1 | 4.3 | GO:0090286 | cytoskeletal anchoring at nuclear membrane(GO:0090286) |
| 2.1 | 21.2 | GO:0048934 | peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935) |
| 2.1 | 8.3 | GO:0035795 | negative regulation of mitochondrial membrane permeability(GO:0035795) |
| 2.1 | 6.2 | GO:1903334 | positive regulation of protein folding(GO:1903334) |
| 2.0 | 6.1 | GO:0045658 | regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659) |
| 2.0 | 8.2 | GO:0001880 | Mullerian duct regression(GO:0001880) |
| 2.0 | 10.1 | GO:0051684 | maintenance of Golgi location(GO:0051684) |
| 2.0 | 6.0 | GO:0036092 | phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092) |
| 2.0 | 5.9 | GO:0003162 | atrioventricular node development(GO:0003162) |
| 2.0 | 7.8 | GO:0070345 | negative regulation of fat cell proliferation(GO:0070345) |
| 1.9 | 5.8 | GO:0060821 | inactivation of X chromosome by DNA methylation(GO:0060821) |
| 1.9 | 11.5 | GO:0071883 | activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883) |
| 1.9 | 5.7 | GO:0090649 | response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650) |
| 1.9 | 13.2 | GO:0007296 | vitellogenesis(GO:0007296) |
| 1.9 | 15.0 | GO:0033564 | anterior/posterior axon guidance(GO:0033564) |
| 1.9 | 3.7 | GO:1904468 | negative regulation of tumor necrosis factor secretion(GO:1904468) |
| 1.9 | 5.6 | GO:0003345 | proepicardium cell migration involved in pericardium morphogenesis(GO:0003345) |
| 1.8 | 5.5 | GO:0070315 | G1 to G0 transition involved in cell differentiation(GO:0070315) |
| 1.8 | 26.9 | GO:0032092 | positive regulation of protein binding(GO:0032092) |
| 1.8 | 7.1 | GO:2000110 | protein sialylation(GO:1990743) negative regulation of macrophage apoptotic process(GO:2000110) |
| 1.8 | 42.4 | GO:0042462 | eye photoreceptor cell development(GO:0042462) |
| 1.8 | 3.5 | GO:0035973 | aggrephagy(GO:0035973) |
| 1.7 | 13.8 | GO:0010587 | miRNA catabolic process(GO:0010587) |
| 1.7 | 5.0 | GO:0006776 | vitamin A metabolic process(GO:0006776) |
| 1.7 | 13.3 | GO:0018026 | peptidyl-lysine monomethylation(GO:0018026) |
| 1.6 | 11.1 | GO:0051611 | negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) |
| 1.6 | 4.7 | GO:0034140 | granuloma formation(GO:0002432) negative regulation of toll-like receptor 3 signaling pathway(GO:0034140) toll-like receptor 5 signaling pathway(GO:0034146) |
| 1.6 | 28.3 | GO:0000920 | cell separation after cytokinesis(GO:0000920) |
| 1.5 | 4.6 | GO:0006592 | ornithine biosynthetic process(GO:0006592) |
| 1.5 | 9.2 | GO:0015014 | heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014) |
| 1.5 | 6.0 | GO:0032493 | response to bacterial lipoprotein(GO:0032493) |
| 1.5 | 6.0 | GO:1904565 | response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566) |
| 1.5 | 13.4 | GO:2000794 | positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501) regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000794) |
| 1.5 | 8.9 | GO:0000160 | phosphorelay signal transduction system(GO:0000160) |
| 1.5 | 26.2 | GO:0046069 | cGMP catabolic process(GO:0046069) |
| 1.4 | 13.0 | GO:0032525 | somite rostral/caudal axis specification(GO:0032525) |
| 1.4 | 4.3 | GO:0002572 | pro-T cell differentiation(GO:0002572) |
| 1.4 | 32.3 | GO:0030866 | cortical actin cytoskeleton organization(GO:0030866) |
| 1.4 | 9.8 | GO:0033184 | positive regulation of histone ubiquitination(GO:0033184) |
| 1.4 | 7.0 | GO:1904690 | regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690) |
| 1.4 | 5.5 | GO:0038163 | thrombopoietin-mediated signaling pathway(GO:0038163) |
| 1.4 | 6.9 | GO:0050912 | detection of chemical stimulus involved in sensory perception(GO:0050907) detection of chemical stimulus involved in sensory perception of taste(GO:0050912) |
| 1.4 | 8.1 | GO:0030643 | cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502) |
| 1.3 | 4.0 | GO:0090327 | negative regulation of locomotion involved in locomotory behavior(GO:0090327) |
| 1.3 | 18.6 | GO:0034377 | plasma lipoprotein particle assembly(GO:0034377) |
| 1.3 | 3.9 | GO:1990859 | cellular response to endothelin(GO:1990859) |
| 1.3 | 24.3 | GO:0035025 | positive regulation of Rho protein signal transduction(GO:0035025) |
| 1.3 | 7.6 | GO:0050832 | defense response to fungus(GO:0050832) |
| 1.3 | 25.2 | GO:0014912 | negative regulation of smooth muscle cell migration(GO:0014912) |
| 1.3 | 2.5 | GO:0060244 | negative regulation of cell proliferation involved in contact inhibition(GO:0060244) |
| 1.3 | 6.3 | GO:0035063 | nuclear speck organization(GO:0035063) |
| 1.2 | 1.2 | GO:1903377 | negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377) |
| 1.2 | 18.4 | GO:0001833 | inner cell mass cell proliferation(GO:0001833) |
| 1.2 | 9.6 | GO:0006265 | DNA topological change(GO:0006265) |
| 1.2 | 27.6 | GO:2000052 | positive regulation of non-canonical Wnt signaling pathway(GO:2000052) |
| 1.2 | 3.6 | GO:0015712 | hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760) |
| 1.2 | 15.3 | GO:0043252 | sodium-independent organic anion transport(GO:0043252) |
| 1.2 | 9.4 | GO:0006977 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400) |
| 1.2 | 15.3 | GO:0006337 | nucleosome disassembly(GO:0006337) |
| 1.2 | 4.7 | GO:0060017 | parathyroid gland development(GO:0060017) |
| 1.2 | 3.5 | GO:2000312 | regulation of kainate selective glutamate receptor activity(GO:2000312) |
| 1.1 | 2.3 | GO:0045343 | MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343) positive regulation of MHC class I biosynthetic process(GO:0045345) |
| 1.1 | 6.8 | GO:0051013 | microtubule severing(GO:0051013) |
| 1.1 | 9.1 | GO:0032776 | DNA methylation on cytosine(GO:0032776) |
| 1.1 | 16.8 | GO:0035970 | peptidyl-threonine dephosphorylation(GO:0035970) |
| 1.1 | 7.8 | GO:0035331 | negative regulation of hippo signaling(GO:0035331) |
| 1.1 | 13.1 | GO:0007250 | activation of NF-kappaB-inducing kinase activity(GO:0007250) |
| 1.1 | 2.2 | GO:0040010 | positive regulation of growth rate(GO:0040010) |
| 1.1 | 16.2 | GO:0031987 | locomotion involved in locomotory behavior(GO:0031987) |
| 1.1 | 15.0 | GO:0033327 | Leydig cell differentiation(GO:0033327) |
| 1.1 | 3.2 | GO:0048209 | regulation of vesicle targeting, to, from or within Golgi(GO:0048209) |
| 1.1 | 6.3 | GO:0036066 | protein O-linked fucosylation(GO:0036066) |
| 1.1 | 26.3 | GO:0051642 | centrosome localization(GO:0051642) |
| 1.0 | 17.5 | GO:2001275 | positive regulation of glucose import in response to insulin stimulus(GO:2001275) |
| 1.0 | 6.0 | GO:0072553 | terminal button organization(GO:0072553) |
| 1.0 | 23.1 | GO:0007035 | vacuolar acidification(GO:0007035) |
| 1.0 | 18.0 | GO:0045793 | positive regulation of cell size(GO:0045793) |
| 1.0 | 9.0 | GO:0035280 | miRNA loading onto RISC involved in gene silencing by miRNA(GO:0035280) |
| 1.0 | 20.7 | GO:0060009 | Sertoli cell development(GO:0060009) |
| 1.0 | 7.9 | GO:0031087 | deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087) |
| 1.0 | 5.9 | GO:0034242 | negative regulation of syncytium formation by plasma membrane fusion(GO:0034242) |
| 1.0 | 2.9 | GO:0051562 | negative regulation of mitochondrial calcium ion concentration(GO:0051562) |
| 1.0 | 10.5 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
| 1.0 | 8.6 | GO:0098789 | pre-mRNA cleavage required for polyadenylation(GO:0098789) |
| 1.0 | 2.9 | GO:0021698 | cerebellar cortex structural organization(GO:0021698) |
| 1.0 | 4.8 | GO:0035845 | photoreceptor cell outer segment organization(GO:0035845) |
| 0.9 | 10.4 | GO:0045671 | negative regulation of osteoclast differentiation(GO:0045671) |
| 0.9 | 4.7 | GO:0038032 | termination of G-protein coupled receptor signaling pathway(GO:0038032) |
| 0.9 | 4.7 | GO:0061073 | ciliary body morphogenesis(GO:0061073) |
| 0.9 | 8.4 | GO:0015838 | amino-acid betaine transport(GO:0015838) |
| 0.9 | 4.6 | GO:0051987 | positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987) |
| 0.9 | 0.9 | GO:0031017 | exocrine pancreas development(GO:0031017) |
| 0.9 | 17.4 | GO:0043968 | histone H2A acetylation(GO:0043968) |
| 0.9 | 4.6 | GO:0071394 | cellular response to testosterone stimulus(GO:0071394) |
| 0.9 | 7.3 | GO:0016338 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338) |
| 0.9 | 2.7 | GO:0007161 | calcium-independent cell-matrix adhesion(GO:0007161) |
| 0.9 | 5.4 | GO:0070092 | regulation of glucagon secretion(GO:0070092) |
| 0.9 | 2.7 | GO:0048239 | negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695) |
| 0.9 | 3.5 | GO:1903966 | monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966) |
| 0.9 | 11.2 | GO:0042347 | negative regulation of NF-kappaB import into nucleus(GO:0042347) |
| 0.9 | 1.7 | GO:0050891 | regulation of water loss via skin(GO:0033561) multicellular organismal water homeostasis(GO:0050891) establishment of skin barrier(GO:0061436) |
| 0.9 | 36.7 | GO:0060612 | adipose tissue development(GO:0060612) |
| 0.8 | 7.5 | GO:0048280 | vesicle fusion with Golgi apparatus(GO:0048280) |
| 0.8 | 9.2 | GO:0034498 | early endosome to Golgi transport(GO:0034498) |
| 0.8 | 2.5 | GO:0090285 | negative regulation of protein glycosylation in Golgi(GO:0090285) |
| 0.8 | 2.5 | GO:0019441 | tryptophan catabolic process(GO:0006569) tryptophan catabolic process to kynurenine(GO:0019441) quinolinate biosynthetic process(GO:0019805) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218) kynurenine metabolic process(GO:0070189) |
| 0.8 | 7.5 | GO:0070236 | negative regulation of activation-induced cell death of T cells(GO:0070236) |
| 0.8 | 5.0 | GO:0072718 | response to cisplatin(GO:0072718) |
| 0.8 | 5.7 | GO:1903608 | protein localization to cytoplasmic stress granule(GO:1903608) |
| 0.8 | 7.3 | GO:0038026 | reelin-mediated signaling pathway(GO:0038026) |
| 0.8 | 4.0 | GO:0006868 | glutamine transport(GO:0006868) |
| 0.8 | 4.0 | GO:0090091 | positive regulation of extracellular matrix disassembly(GO:0090091) |
| 0.8 | 14.5 | GO:0048172 | regulation of short-term neuronal synaptic plasticity(GO:0048172) inhibitory postsynaptic potential(GO:0060080) |
| 0.8 | 17.4 | GO:0016242 | negative regulation of macroautophagy(GO:0016242) |
| 0.8 | 4.5 | GO:2000210 | positive regulation of anoikis(GO:2000210) |
| 0.7 | 4.4 | GO:0016576 | histone dephosphorylation(GO:0016576) |
| 0.7 | 0.7 | GO:0060664 | epithelial cell proliferation involved in salivary gland morphogenesis(GO:0060664) glucagon secretion(GO:0070091) |
| 0.7 | 6.6 | GO:0090209 | negative regulation of triglyceride metabolic process(GO:0090209) |
| 0.7 | 4.3 | GO:0030718 | germ-line stem cell population maintenance(GO:0030718) |
| 0.7 | 19.3 | GO:0007617 | mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705) |
| 0.7 | 2.8 | GO:0010815 | bradykinin catabolic process(GO:0010815) |
| 0.7 | 2.8 | GO:0090282 | positive regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071931) positive regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0090282) |
| 0.7 | 7.6 | GO:0006020 | inositol metabolic process(GO:0006020) |
| 0.7 | 7.6 | GO:0031571 | mitotic G1 DNA damage checkpoint(GO:0031571) |
| 0.7 | 2.8 | GO:0002949 | tRNA threonylcarbamoyladenosine modification(GO:0002949) |
| 0.7 | 5.5 | GO:1902414 | protein localization to cell junction(GO:1902414) |
| 0.7 | 6.1 | GO:0000052 | citrulline metabolic process(GO:0000052) |
| 0.7 | 3.4 | GO:0051823 | regulation of synapse structural plasticity(GO:0051823) |
| 0.7 | 26.2 | GO:0003301 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
| 0.7 | 5.4 | GO:0021796 | cerebral cortex regionalization(GO:0021796) |
| 0.7 | 5.4 | GO:0040031 | snRNA modification(GO:0040031) |
| 0.6 | 14.8 | GO:1902857 | positive regulation of nonmotile primary cilium assembly(GO:1902857) |
| 0.6 | 16.5 | GO:0043551 | regulation of phosphatidylinositol 3-kinase activity(GO:0043551) |
| 0.6 | 5.0 | GO:0031639 | plasminogen activation(GO:0031639) |
| 0.6 | 1.9 | GO:0010814 | substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959) |
| 0.6 | 1.2 | GO:0043403 | skeletal muscle tissue regeneration(GO:0043403) |
| 0.6 | 15.5 | GO:0035329 | hippo signaling(GO:0035329) |
| 0.6 | 3.1 | GO:0033762 | response to glucagon(GO:0033762) |
| 0.6 | 2.5 | GO:0036515 | serotonergic neuron axon guidance(GO:0036515) |
| 0.6 | 20.2 | GO:0031648 | protein destabilization(GO:0031648) |
| 0.6 | 5.5 | GO:0030206 | chondroitin sulfate biosynthetic process(GO:0030206) |
| 0.6 | 11.5 | GO:0042552 | myelination(GO:0042552) |
| 0.6 | 6.0 | GO:0031119 | tRNA pseudouridine synthesis(GO:0031119) |
| 0.6 | 7.7 | GO:0006366 | transcription from RNA polymerase II promoter(GO:0006366) |
| 0.6 | 33.1 | GO:0060999 | positive regulation of dendritic spine development(GO:0060999) |
| 0.6 | 5.9 | GO:1904738 | vascular associated smooth muscle cell migration(GO:1904738) regulation of vascular associated smooth muscle cell migration(GO:1904752) positive regulation of vascular associated smooth muscle cell migration(GO:1904754) |
| 0.6 | 7.6 | GO:0050901 | leukocyte tethering or rolling(GO:0050901) |
| 0.6 | 1.2 | GO:0010593 | negative regulation of lamellipodium assembly(GO:0010593) |
| 0.6 | 5.2 | GO:1900119 | positive regulation of execution phase of apoptosis(GO:1900119) |
| 0.6 | 5.6 | GO:0008209 | androgen metabolic process(GO:0008209) |
| 0.6 | 2.8 | GO:0051012 | microtubule sliding(GO:0051012) |
| 0.6 | 6.1 | GO:1902231 | positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231) |
| 0.5 | 6.0 | GO:0045948 | positive regulation of translational initiation(GO:0045948) |
| 0.5 | 9.8 | GO:0042744 | hydrogen peroxide catabolic process(GO:0042744) |
| 0.5 | 2.1 | GO:0042733 | embryonic digit morphogenesis(GO:0042733) |
| 0.5 | 6.8 | GO:0032967 | positive regulation of collagen biosynthetic process(GO:0032967) |
| 0.5 | 65.7 | GO:0006261 | DNA-dependent DNA replication(GO:0006261) |
| 0.5 | 3.6 | GO:0006348 | chromatin silencing at telomere(GO:0006348) |
| 0.5 | 20.6 | GO:1901998 | toxin transport(GO:1901998) |
| 0.5 | 14.7 | GO:1902042 | negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042) |
| 0.5 | 2.0 | GO:0070295 | renal water absorption(GO:0070295) |
| 0.5 | 1.5 | GO:0060907 | positive regulation of macrophage cytokine production(GO:0060907) |
| 0.5 | 24.7 | GO:0051489 | regulation of filopodium assembly(GO:0051489) |
| 0.5 | 10.3 | GO:0016180 | snRNA processing(GO:0016180) |
| 0.5 | 1.0 | GO:0046104 | thymidine metabolic process(GO:0046104) |
| 0.5 | 14.9 | GO:0010259 | multicellular organism aging(GO:0010259) |
| 0.5 | 3.8 | GO:0015074 | DNA integration(GO:0015074) |
| 0.5 | 1.9 | GO:1901165 | positive regulation of trophoblast cell migration(GO:1901165) |
| 0.5 | 7.5 | GO:0070816 | phosphorylation of RNA polymerase II C-terminal domain(GO:0070816) |
| 0.5 | 5.5 | GO:0071447 | cellular response to hydroperoxide(GO:0071447) |
| 0.5 | 4.6 | GO:0045647 | negative regulation of erythrocyte differentiation(GO:0045647) |
| 0.5 | 3.6 | GO:0048386 | positive regulation of retinoic acid receptor signaling pathway(GO:0048386) |
| 0.5 | 0.5 | GO:1904321 | response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322) |
| 0.5 | 5.4 | GO:0050860 | negative regulation of T cell receptor signaling pathway(GO:0050860) |
| 0.5 | 3.2 | GO:1901339 | regulation of store-operated calcium channel activity(GO:1901339) |
| 0.4 | 9.8 | GO:0002053 | positive regulation of mesenchymal cell proliferation(GO:0002053) |
| 0.4 | 2.6 | GO:0072176 | nephric duct development(GO:0072176) nephric duct morphogenesis(GO:0072178) |
| 0.4 | 0.9 | GO:0031660 | regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) |
| 0.4 | 3.4 | GO:0002643 | regulation of tolerance induction(GO:0002643) |
| 0.4 | 2.1 | GO:0016560 | protein import into peroxisome matrix, docking(GO:0016560) |
| 0.4 | 5.1 | GO:0006012 | galactose metabolic process(GO:0006012) |
| 0.4 | 0.8 | GO:0010726 | positive regulation of hydrogen peroxide metabolic process(GO:0010726) |
| 0.4 | 3.7 | GO:0045176 | apical protein localization(GO:0045176) |
| 0.4 | 2.0 | GO:2000680 | regulation of rubidium ion transport(GO:2000680) |
| 0.4 | 1.6 | GO:2000383 | regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384) |
| 0.4 | 2.4 | GO:0010747 | positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747) |
| 0.4 | 4.7 | GO:0045947 | negative regulation of translational initiation(GO:0045947) |
| 0.4 | 33.2 | GO:0001578 | microtubule bundle formation(GO:0001578) |
| 0.4 | 2.0 | GO:0007096 | regulation of exit from mitosis(GO:0007096) |
| 0.4 | 8.2 | GO:0051764 | actin crosslink formation(GO:0051764) |
| 0.4 | 1.5 | GO:1902514 | regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514) |
| 0.4 | 4.6 | GO:0048672 | positive regulation of collateral sprouting(GO:0048672) |
| 0.4 | 5.3 | GO:0031507 | heterochromatin assembly(GO:0031507) |
| 0.4 | 2.3 | GO:0051571 | positive regulation of histone H3-K4 methylation(GO:0051571) |
| 0.4 | 32.2 | GO:0001678 | cellular glucose homeostasis(GO:0001678) |
| 0.4 | 3.4 | GO:0033148 | positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148) |
| 0.4 | 4.9 | GO:0035414 | negative regulation of catenin import into nucleus(GO:0035414) |
| 0.4 | 10.1 | GO:0034724 | DNA replication-independent nucleosome organization(GO:0034724) |
| 0.4 | 1.5 | GO:0019852 | L-ascorbic acid metabolic process(GO:0019852) |
| 0.4 | 1.5 | GO:0006438 | valyl-tRNA aminoacylation(GO:0006438) |
| 0.4 | 2.5 | GO:0000291 | nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) |
| 0.4 | 10.4 | GO:0045737 | positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) |
| 0.4 | 1.4 | GO:0003376 | sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520) |
| 0.4 | 3.5 | GO:0072600 | establishment of protein localization to Golgi(GO:0072600) |
| 0.3 | 2.1 | GO:0048742 | regulation of skeletal muscle fiber development(GO:0048742) |
| 0.3 | 10.0 | GO:0007094 | mitotic spindle assembly checkpoint(GO:0007094) spindle assembly checkpoint(GO:0071173) |
| 0.3 | 3.0 | GO:0009301 | snRNA transcription(GO:0009301) |
| 0.3 | 2.0 | GO:0044375 | regulation of peroxisome size(GO:0044375) |
| 0.3 | 1.0 | GO:0010616 | negative regulation of cardiac muscle adaptation(GO:0010616) |
| 0.3 | 1.3 | GO:0060040 | retinal bipolar neuron differentiation(GO:0060040) |
| 0.3 | 2.0 | GO:0000290 | deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290) |
| 0.3 | 2.9 | GO:0070574 | cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574) |
| 0.3 | 1.3 | GO:0021910 | smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) |
| 0.3 | 9.0 | GO:0006182 | cGMP biosynthetic process(GO:0006182) |
| 0.3 | 4.5 | GO:0007064 | mitotic sister chromatid cohesion(GO:0007064) |
| 0.3 | 10.8 | GO:0006739 | NADP metabolic process(GO:0006739) |
| 0.3 | 21.2 | GO:0051289 | protein homotetramerization(GO:0051289) |
| 0.3 | 2.2 | GO:0036342 | post-anal tail morphogenesis(GO:0036342) |
| 0.3 | 3.7 | GO:0010758 | regulation of macrophage chemotaxis(GO:0010758) |
| 0.3 | 9.8 | GO:0051290 | protein heterotetramerization(GO:0051290) |
| 0.3 | 1.5 | GO:0001711 | endodermal cell fate commitment(GO:0001711) |
| 0.3 | 8.2 | GO:0040015 | negative regulation of multicellular organism growth(GO:0040015) |
| 0.3 | 0.9 | GO:0030854 | positive regulation of granulocyte differentiation(GO:0030854) |
| 0.3 | 5.2 | GO:0043153 | entrainment of circadian clock by photoperiod(GO:0043153) |
| 0.3 | 3.7 | GO:0051451 | myoblast migration(GO:0051451) |
| 0.3 | 2.8 | GO:0045760 | positive regulation of action potential(GO:0045760) |
| 0.3 | 1.1 | GO:0036438 | maintenance of lens transparency(GO:0036438) |
| 0.3 | 3.6 | GO:0090205 | positive regulation of cholesterol biosynthetic process(GO:0045542) positive regulation of cholesterol metabolic process(GO:0090205) |
| 0.3 | 4.4 | GO:0071480 | cellular response to gamma radiation(GO:0071480) |
| 0.3 | 1.4 | GO:0014886 | transition between slow and fast fiber(GO:0014886) |
| 0.3 | 1.1 | GO:0033194 | response to hydroperoxide(GO:0033194) |
| 0.3 | 1.4 | GO:1900095 | regulation of dosage compensation by inactivation of X chromosome(GO:1900095) |
| 0.3 | 14.3 | GO:0006367 | transcription initiation from RNA polymerase II promoter(GO:0006367) |
| 0.3 | 1.0 | GO:0070162 | adiponectin secretion(GO:0070162) regulation of adiponectin secretion(GO:0070163) negative regulation of adiponectin secretion(GO:0070164) |
| 0.3 | 0.5 | GO:2000646 | negative regulation of PERK-mediated unfolded protein response(GO:1903898) positive regulation of receptor catabolic process(GO:2000646) |
| 0.3 | 2.5 | GO:0070914 | UV-damage excision repair(GO:0070914) |
| 0.3 | 2.0 | GO:0031468 | nuclear envelope reassembly(GO:0031468) |
| 0.3 | 5.5 | GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146) |
| 0.2 | 4.7 | GO:0006958 | complement activation, classical pathway(GO:0006958) |
| 0.2 | 7.7 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
| 0.2 | 1.0 | GO:0090190 | positive regulation of mesonephros development(GO:0061213) regulation of mesonephros development(GO:0061217) regulation of branching involved in ureteric bud morphogenesis(GO:0090189) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190) |
| 0.2 | 2.9 | GO:0002076 | osteoblast development(GO:0002076) |
| 0.2 | 19.6 | GO:0006892 | post-Golgi vesicle-mediated transport(GO:0006892) |
| 0.2 | 4.2 | GO:0010569 | regulation of double-strand break repair via homologous recombination(GO:0010569) |
| 0.2 | 4.1 | GO:0031954 | positive regulation of protein autophosphorylation(GO:0031954) |
| 0.2 | 1.1 | GO:0048704 | embryonic skeletal system morphogenesis(GO:0048704) |
| 0.2 | 3.6 | GO:0048026 | positive regulation of mRNA splicing, via spliceosome(GO:0048026) |
| 0.2 | 12.3 | GO:0043488 | regulation of mRNA stability(GO:0043488) |
| 0.2 | 14.1 | GO:0090090 | negative regulation of canonical Wnt signaling pathway(GO:0090090) |
| 0.2 | 1.3 | GO:0007221 | positive regulation of transcription of Notch receptor target(GO:0007221) |
| 0.2 | 16.1 | GO:0006986 | response to unfolded protein(GO:0006986) |
| 0.2 | 1.1 | GO:2000271 | positive regulation of fibroblast apoptotic process(GO:2000271) |
| 0.2 | 0.2 | GO:0061314 | Notch signaling involved in heart development(GO:0061314) |
| 0.2 | 12.7 | GO:0002028 | regulation of sodium ion transport(GO:0002028) |
| 0.2 | 5.5 | GO:0045746 | negative regulation of Notch signaling pathway(GO:0045746) |
| 0.2 | 5.2 | GO:0032330 | regulation of chondrocyte differentiation(GO:0032330) |
| 0.2 | 5.6 | GO:0000470 | maturation of LSU-rRNA(GO:0000470) |
| 0.2 | 0.6 | GO:1900186 | negative regulation of clathrin-mediated endocytosis(GO:1900186) |
| 0.2 | 11.6 | GO:0007601 | visual perception(GO:0007601) |
| 0.2 | 2.5 | GO:0099500 | synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500) |
| 0.2 | 3.6 | GO:0007178 | transmembrane receptor protein serine/threonine kinase signaling pathway(GO:0007178) |
| 0.2 | 1.5 | GO:0046085 | adenosine metabolic process(GO:0046085) |
| 0.2 | 4.8 | GO:0080171 | lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171) |
| 0.2 | 10.2 | GO:0010508 | positive regulation of autophagy(GO:0010508) |
| 0.2 | 4.8 | GO:0031572 | G2 DNA damage checkpoint(GO:0031572) |
| 0.2 | 2.1 | GO:0009148 | CTP biosynthetic process(GO:0006241) pyrimidine nucleoside triphosphate biosynthetic process(GO:0009148) pyrimidine ribonucleoside triphosphate biosynthetic process(GO:0009209) CTP metabolic process(GO:0046036) |
| 0.2 | 1.9 | GO:0021794 | thalamus development(GO:0021794) |
| 0.2 | 11.9 | GO:0010950 | positive regulation of endopeptidase activity(GO:0010950) |
| 0.2 | 4.9 | GO:0001825 | blastocyst formation(GO:0001825) |
| 0.2 | 1.0 | GO:0045056 | transcytosis(GO:0045056) |
| 0.2 | 20.0 | GO:1990830 | response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830) |
| 0.2 | 4.9 | GO:0043666 | regulation of phosphoprotein phosphatase activity(GO:0043666) |
| 0.2 | 8.8 | GO:0042147 | retrograde transport, endosome to Golgi(GO:0042147) |
| 0.2 | 0.8 | GO:0007398 | ectoderm development(GO:0007398) |
| 0.2 | 1.4 | GO:0060216 | definitive hemopoiesis(GO:0060216) |
| 0.2 | 14.1 | GO:0043484 | regulation of RNA splicing(GO:0043484) |
| 0.2 | 2.4 | GO:0000338 | protein deneddylation(GO:0000338) |
| 0.2 | 0.8 | GO:0016479 | negative regulation of transcription from RNA polymerase I promoter(GO:0016479) negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837) |
| 0.2 | 3.1 | GO:0010507 | negative regulation of autophagy(GO:0010507) |
| 0.2 | 3.4 | GO:0001824 | blastocyst development(GO:0001824) |
| 0.2 | 0.5 | GO:0018094 | protein polyglycylation(GO:0018094) |
| 0.2 | 1.4 | GO:0045723 | positive regulation of fatty acid biosynthetic process(GO:0045723) |
| 0.1 | 3.0 | GO:0035019 | somatic stem cell population maintenance(GO:0035019) |
| 0.1 | 5.5 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
| 0.1 | 0.7 | GO:0032687 | negative regulation of interferon-alpha production(GO:0032687) |
| 0.1 | 0.9 | GO:0030953 | astral microtubule organization(GO:0030953) |
| 0.1 | 2.8 | GO:0006383 | transcription from RNA polymerase III promoter(GO:0006383) |
| 0.1 | 16.7 | GO:0030217 | T cell differentiation(GO:0030217) |
| 0.1 | 0.7 | GO:0090050 | positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) |
| 0.1 | 18.7 | GO:0032259 | methylation(GO:0032259) |
| 0.1 | 0.3 | GO:0044406 | adhesion of symbiont to host(GO:0044406) |
| 0.1 | 3.8 | GO:0006024 | glycosaminoglycan biosynthetic process(GO:0006024) |
| 0.1 | 0.4 | GO:0007158 | neuron cell-cell adhesion(GO:0007158) |
| 0.1 | 3.5 | GO:0032007 | negative regulation of TOR signaling(GO:0032007) |
| 0.1 | 0.8 | GO:0031062 | positive regulation of histone methylation(GO:0031062) |
| 0.1 | 0.9 | GO:0030382 | sperm mitochondrion organization(GO:0030382) |
| 0.1 | 3.0 | GO:0042475 | odontogenesis of dentin-containing tooth(GO:0042475) |
| 0.1 | 6.2 | GO:0070936 | protein K48-linked ubiquitination(GO:0070936) |
| 0.1 | 2.0 | GO:0031643 | positive regulation of myelination(GO:0031643) |
| 0.1 | 0.4 | GO:0070649 | meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038) formin-nucleated actin cable assembly(GO:0070649) |
| 0.1 | 2.9 | GO:0046856 | phosphatidylinositol dephosphorylation(GO:0046856) |
| 0.1 | 1.3 | GO:0002098 | tRNA wobble uridine modification(GO:0002098) |
| 0.1 | 8.4 | GO:0000910 | cytokinesis(GO:0000910) |
| 0.1 | 2.4 | GO:0060324 | face development(GO:0060324) |
| 0.1 | 0.5 | GO:1904645 | response to beta-amyloid(GO:1904645) |
| 0.1 | 2.9 | GO:0060976 | coronary vasculature development(GO:0060976) |
| 0.1 | 0.3 | GO:0002553 | histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553) |
| 0.1 | 0.6 | GO:0060218 | hematopoietic stem cell differentiation(GO:0060218) |
| 0.1 | 26.9 | GO:0016569 | covalent chromatin modification(GO:0016569) |
| 0.1 | 4.2 | GO:0006342 | chromatin silencing(GO:0006342) |
| 0.1 | 0.1 | GO:0014002 | astrocyte development(GO:0014002) |
| 0.1 | 0.5 | GO:0009299 | mRNA transcription(GO:0009299) |
| 0.1 | 0.2 | GO:0006432 | phenylalanyl-tRNA aminoacylation(GO:0006432) |
| 0.1 | 1.6 | GO:0006096 | glycolytic process(GO:0006096) ATP generation from ADP(GO:0006757) |
| 0.1 | 2.5 | GO:0043154 | negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154) |
| 0.1 | 1.1 | GO:0050684 | regulation of mRNA processing(GO:0050684) |
| 0.1 | 0.3 | GO:1901642 | purine nucleoside transmembrane transport(GO:0015860) nucleoside transmembrane transport(GO:1901642) |
| 0.1 | 2.7 | GO:0006505 | GPI anchor metabolic process(GO:0006505) GPI anchor biosynthetic process(GO:0006506) |
| 0.1 | 2.2 | GO:0007218 | neuropeptide signaling pathway(GO:0007218) |
| 0.0 | 2.1 | GO:0031338 | regulation of vesicle fusion(GO:0031338) |
| 0.0 | 1.1 | GO:0061099 | negative regulation of protein tyrosine kinase activity(GO:0061099) |
| 0.0 | 0.7 | GO:0006749 | glutathione metabolic process(GO:0006749) |
| 0.0 | 0.2 | GO:0015842 | aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) |
| 0.0 | 1.1 | GO:0000387 | spliceosomal snRNP assembly(GO:0000387) |
| 0.0 | 0.1 | GO:1901052 | sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053) |
| 0.0 | 1.2 | GO:0030518 | intracellular steroid hormone receptor signaling pathway(GO:0030518) |
| 0.0 | 1.4 | GO:0002181 | cytoplasmic translation(GO:0002181) |
| 0.0 | 1.8 | GO:0051604 | protein maturation(GO:0051604) |
| 0.0 | 0.4 | GO:0032933 | response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501) |
| 0.0 | 0.4 | GO:0007608 | sensory perception of smell(GO:0007608) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 42.4 | 127.1 | GO:0071149 | TEAD-2-YAP complex(GO:0071149) |
| 15.9 | 63.4 | GO:0008623 | CHRAC(GO:0008623) |
| 12.0 | 35.9 | GO:0071148 | TEAD-1-YAP complex(GO:0071148) |
| 9.3 | 28.0 | GO:0071914 | prominosome(GO:0071914) |
| 9.3 | 46.6 | GO:0005971 | ribonucleoside-diphosphate reductase complex(GO:0005971) |
| 6.7 | 20.2 | GO:0042585 | germinal vesicle(GO:0042585) |
| 5.3 | 15.8 | GO:0005673 | transcription factor TFIIE complex(GO:0005673) |
| 5.3 | 26.3 | GO:0036449 | microtubule minus-end(GO:0036449) |
| 4.7 | 51.6 | GO:1990907 | beta-catenin-TCF complex(GO:1990907) |
| 4.6 | 27.9 | GO:0070937 | CRD-mediated mRNA stability complex(GO:0070937) |
| 4.5 | 80.3 | GO:0035102 | PRC1 complex(GO:0035102) |
| 4.3 | 17.1 | GO:0042105 | alpha-beta T cell receptor complex(GO:0042105) |
| 4.3 | 55.3 | GO:0043219 | lateral loop(GO:0043219) |
| 4.0 | 4.0 | GO:1902737 | dendritic filopodium(GO:1902737) |
| 4.0 | 12.0 | GO:0038045 | large latent transforming growth factor-beta complex(GO:0038045) |
| 3.8 | 15.2 | GO:0097129 | cyclin D2-CDK4 complex(GO:0097129) |
| 3.5 | 28.2 | GO:0034993 | microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993) |
| 3.4 | 20.6 | GO:1990356 | sumoylated E2 ligase complex(GO:1990356) |
| 3.1 | 12.5 | GO:0098559 | cytoplasmic side of early endosome membrane(GO:0098559) |
| 3.1 | 9.2 | GO:0030905 | retromer, tubulation complex(GO:0030905) |
| 3.0 | 26.9 | GO:0030478 | actin cap(GO:0030478) |
| 2.9 | 2.9 | GO:0035101 | FACT complex(GO:0035101) |
| 2.9 | 8.7 | GO:0002944 | cyclin K-CDK12 complex(GO:0002944) |
| 2.8 | 16.9 | GO:0031094 | platelet dense tubular network(GO:0031094) |
| 2.7 | 47.8 | GO:0032156 | septin cytoskeleton(GO:0032156) |
| 2.6 | 17.9 | GO:0016580 | Sin3 complex(GO:0016580) |
| 2.4 | 14.5 | GO:0032983 | kainate selective glutamate receptor complex(GO:0032983) |
| 2.4 | 9.6 | GO:0001651 | dense fibrillar component(GO:0001651) |
| 2.4 | 7.1 | GO:1990047 | spindle matrix(GO:1990047) |
| 2.3 | 7.0 | GO:0031680 | G-protein beta/gamma-subunit complex(GO:0031680) |
| 2.3 | 9.1 | GO:0030289 | protein phosphatase 4 complex(GO:0030289) |
| 2.2 | 32.8 | GO:0097431 | mitotic spindle pole(GO:0097431) |
| 2.1 | 21.1 | GO:0035748 | myelin sheath abaxonal region(GO:0035748) |
| 2.1 | 29.0 | GO:0042788 | polysomal ribosome(GO:0042788) |
| 2.0 | 5.9 | GO:0002193 | MAML1-RBP-Jkappa- ICN1 complex(GO:0002193) |
| 1.9 | 13.6 | GO:0044352 | pinosome(GO:0044352) macropinosome(GO:0044354) |
| 1.9 | 11.5 | GO:0005726 | perichromatin fibrils(GO:0005726) |
| 1.9 | 18.6 | GO:0043205 | microfibril(GO:0001527) fibril(GO:0043205) |
| 1.8 | 5.5 | GO:1990851 | Wnt-Frizzled-LRP5/6 complex(GO:1990851) |
| 1.8 | 14.1 | GO:0005833 | hemoglobin complex(GO:0005833) |
| 1.7 | 22.0 | GO:0043596 | nuclear replication fork(GO:0043596) |
| 1.7 | 6.8 | GO:0008537 | proteasome activator complex(GO:0008537) |
| 1.7 | 8.4 | GO:0032777 | Piccolo NuA4 histone acetyltransferase complex(GO:0032777) |
| 1.7 | 13.5 | GO:0044224 | juxtaparanode region of axon(GO:0044224) |
| 1.6 | 13.2 | GO:0043220 | Schmidt-Lanterman incisure(GO:0043220) |
| 1.5 | 13.9 | GO:0016600 | flotillin complex(GO:0016600) |
| 1.5 | 4.5 | GO:0001652 | granular component(GO:0001652) |
| 1.5 | 4.5 | GO:0031251 | PAN complex(GO:0031251) |
| 1.5 | 25.3 | GO:0000145 | exocyst(GO:0000145) |
| 1.4 | 32.7 | GO:0016581 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
| 1.3 | 198.1 | GO:0090575 | RNA polymerase II transcription factor complex(GO:0090575) |
| 1.3 | 178.7 | GO:0032993 | protein-DNA complex(GO:0032993) |
| 1.3 | 13.0 | GO:0016529 | sarcoplasmic reticulum(GO:0016529) |
| 1.3 | 25.2 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 1.2 | 345.3 | GO:0005667 | transcription factor complex(GO:0005667) |
| 1.2 | 14.6 | GO:0044294 | dendritic growth cone(GO:0044294) |
| 1.2 | 73.0 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
| 1.2 | 3.5 | GO:0034274 | Atg12-Atg5-Atg16 complex(GO:0034274) |
| 1.1 | 21.8 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
| 1.1 | 4.5 | GO:0070822 | Sin3-type complex(GO:0070822) |
| 1.1 | 4.5 | GO:0030906 | retromer, cargo-selective complex(GO:0030906) |
| 1.0 | 24.1 | GO:0072562 | blood microparticle(GO:0072562) |
| 1.0 | 14.4 | GO:0031011 | Ino80 complex(GO:0031011) |
| 1.0 | 9.0 | GO:0070578 | micro-ribonucleoprotein complex(GO:0035068) RISC-loading complex(GO:0070578) |
| 1.0 | 63.6 | GO:0016459 | myosin complex(GO:0016459) |
| 1.0 | 3.0 | GO:0001674 | female germ cell nucleus(GO:0001674) |
| 1.0 | 4.0 | GO:0044307 | dendritic branch(GO:0044307) |
| 1.0 | 10.6 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
| 1.0 | 18.2 | GO:0001891 | phagocytic cup(GO:0001891) |
| 0.9 | 3.8 | GO:0071008 | U2-type post-mRNA release spliceosomal complex(GO:0071008) |
| 0.9 | 33.5 | GO:0001772 | immunological synapse(GO:0001772) |
| 0.9 | 4.6 | GO:1990023 | mitotic spindle midzone(GO:1990023) |
| 0.9 | 53.0 | GO:0005871 | kinesin complex(GO:0005871) |
| 0.9 | 6.9 | GO:0070652 | HAUS complex(GO:0070652) |
| 0.8 | 35.8 | GO:0002102 | podosome(GO:0002102) |
| 0.8 | 13.1 | GO:0032039 | integrator complex(GO:0032039) |
| 0.8 | 3.3 | GO:1990421 | subtelomeric heterochromatin(GO:1990421) nuclear subtelomeric heterochromatin(GO:1990707) |
| 0.8 | 5.7 | GO:0097165 | nuclear stress granule(GO:0097165) |
| 0.8 | 12.7 | GO:0036038 | MKS complex(GO:0036038) |
| 0.8 | 4.6 | GO:0008024 | cyclin/CDK positive transcription elongation factor complex(GO:0008024) |
| 0.8 | 16.6 | GO:0005942 | phosphatidylinositol 3-kinase complex(GO:0005942) |
| 0.7 | 5.8 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 0.7 | 0.7 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
| 0.7 | 7.1 | GO:0000138 | Golgi trans cisterna(GO:0000138) |
| 0.7 | 45.1 | GO:0005902 | microvillus(GO:0005902) |
| 0.7 | 2.0 | GO:0097487 | multivesicular body, internal vesicle(GO:0097487) |
| 0.7 | 53.6 | GO:0001669 | acrosomal vesicle(GO:0001669) |
| 0.6 | 61.4 | GO:0000932 | cytoplasmic mRNA processing body(GO:0000932) |
| 0.6 | 15.4 | GO:0030285 | integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563) |
| 0.6 | 4.4 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
| 0.6 | 6.8 | GO:0044666 | MLL3/4 complex(GO:0044666) |
| 0.6 | 7.9 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
| 0.6 | 42.3 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.6 | 7.1 | GO:0070938 | contractile ring(GO:0070938) |
| 0.6 | 13.6 | GO:0001741 | XY body(GO:0001741) |
| 0.6 | 11.7 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
| 0.6 | 19.6 | GO:1990391 | DNA repair complex(GO:1990391) |
| 0.6 | 19.8 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
| 0.6 | 15.3 | GO:0030140 | trans-Golgi network transport vesicle(GO:0030140) |
| 0.6 | 5.6 | GO:0070545 | PeBoW complex(GO:0070545) |
| 0.6 | 5.0 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
| 0.6 | 2.8 | GO:0000408 | EKC/KEOPS complex(GO:0000408) |
| 0.5 | 2.1 | GO:0017071 | intracellular cyclic nucleotide activated cation channel complex(GO:0017071) |
| 0.5 | 2.0 | GO:0035985 | senescence-associated heterochromatin focus(GO:0035985) |
| 0.5 | 22.7 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.5 | 4.5 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.5 | 1.5 | GO:0017109 | glutamate-cysteine ligase complex(GO:0017109) |
| 0.5 | 7.1 | GO:0005640 | nuclear outer membrane(GO:0005640) |
| 0.5 | 4.2 | GO:0005677 | chromatin silencing complex(GO:0005677) |
| 0.5 | 5.5 | GO:0044295 | axonal growth cone(GO:0044295) |
| 0.5 | 8.6 | GO:0005847 | mRNA cleavage and polyadenylation specificity factor complex(GO:0005847) |
| 0.5 | 6.3 | GO:0005922 | connexon complex(GO:0005922) |
| 0.4 | 2.2 | GO:0016342 | catenin complex(GO:0016342) |
| 0.4 | 5.5 | GO:0044322 | endoplasmic reticulum quality control compartment(GO:0044322) |
| 0.4 | 4.7 | GO:0042571 | immunoglobulin complex, circulating(GO:0042571) |
| 0.4 | 7.5 | GO:0012507 | ER to Golgi transport vesicle membrane(GO:0012507) |
| 0.4 | 31.9 | GO:0016363 | nuclear matrix(GO:0016363) |
| 0.4 | 12.7 | GO:0005876 | spindle microtubule(GO:0005876) |
| 0.4 | 10.4 | GO:0031519 | PcG protein complex(GO:0031519) |
| 0.4 | 1.1 | GO:0031021 | interphase microtubule organizing center(GO:0031021) |
| 0.4 | 45.9 | GO:0005923 | bicellular tight junction(GO:0005923) |
| 0.4 | 12.1 | GO:0008180 | COP9 signalosome(GO:0008180) |
| 0.4 | 2.5 | GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex(GO:0031465) |
| 0.4 | 6.0 | GO:0005771 | multivesicular body(GO:0005771) |
| 0.3 | 16.9 | GO:0005844 | polysome(GO:0005844) |
| 0.3 | 30.4 | GO:0000776 | kinetochore(GO:0000776) |
| 0.3 | 2.8 | GO:0000813 | ESCRT I complex(GO:0000813) |
| 0.3 | 3.1 | GO:0005750 | mitochondrial respiratory chain complex III(GO:0005750) |
| 0.3 | 25.7 | GO:0000922 | spindle pole(GO:0000922) |
| 0.3 | 4.8 | GO:0032420 | stereocilium(GO:0032420) |
| 0.3 | 1.9 | GO:0036195 | muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195) |
| 0.3 | 6.9 | GO:0016592 | mediator complex(GO:0016592) |
| 0.3 | 5.3 | GO:0034399 | nuclear periphery(GO:0034399) |
| 0.3 | 56.8 | GO:0005815 | microtubule organizing center(GO:0005815) |
| 0.3 | 70.2 | GO:0043235 | receptor complex(GO:0043235) |
| 0.3 | 2.1 | GO:0031597 | cytosolic proteasome complex(GO:0031597) |
| 0.2 | 21.6 | GO:1990204 | oxidoreductase complex(GO:1990204) |
| 0.2 | 1.0 | GO:0097447 | dendritic tree(GO:0097447) |
| 0.2 | 1.4 | GO:0042589 | zymogen granule membrane(GO:0042589) |
| 0.2 | 1.6 | GO:0005642 | annulate lamellae(GO:0005642) |
| 0.2 | 0.9 | GO:0019773 | proteasome core complex, alpha-subunit complex(GO:0019773) |
| 0.2 | 16.5 | GO:0005776 | autophagosome(GO:0005776) |
| 0.2 | 3.2 | GO:0005797 | Golgi medial cisterna(GO:0005797) |
| 0.2 | 1.6 | GO:0002177 | manchette(GO:0002177) |
| 0.2 | 0.2 | GO:0032040 | small-subunit processome(GO:0032040) |
| 0.2 | 8.6 | GO:0030864 | cortical actin cytoskeleton(GO:0030864) |
| 0.2 | 6.7 | GO:0097014 | axoneme(GO:0005930) ciliary plasm(GO:0097014) |
| 0.2 | 1.0 | GO:0020005 | symbiont-containing vacuole membrane(GO:0020005) |
| 0.2 | 0.2 | GO:1990761 | growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812) |
| 0.1 | 9.0 | GO:0030880 | RNA polymerase complex(GO:0030880) |
| 0.1 | 0.7 | GO:0030877 | beta-catenin destruction complex(GO:0030877) |
| 0.1 | 0.5 | GO:0099569 | presynaptic cytoskeleton(GO:0099569) |
| 0.1 | 16.9 | GO:0009897 | external side of plasma membrane(GO:0009897) |
| 0.1 | 6.6 | GO:0042641 | actomyosin(GO:0042641) |
| 0.1 | 1.2 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
| 0.1 | 1.1 | GO:0032797 | SMN complex(GO:0032797) |
| 0.1 | 1.6 | GO:0034707 | chloride channel complex(GO:0034707) |
| 0.1 | 15.4 | GO:0000785 | chromatin(GO:0000785) |
| 0.1 | 59.7 | GO:0005730 | nucleolus(GO:0005730) |
| 0.1 | 19.9 | GO:0000151 | ubiquitin ligase complex(GO:0000151) |
| 0.1 | 1.8 | GO:0071004 | U2-type prespliceosome(GO:0071004) |
| 0.1 | 0.6 | GO:0060293 | P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293) |
| 0.1 | 205.2 | GO:0005654 | nucleoplasm(GO:0005654) |
| 0.1 | 5.7 | GO:0005905 | clathrin-coated pit(GO:0005905) |
| 0.1 | 0.5 | GO:0097443 | sorting endosome(GO:0097443) |
| 0.1 | 4.9 | GO:0043198 | dendritic shaft(GO:0043198) |
| 0.1 | 1.7 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
| 0.1 | 2.0 | GO:0005779 | integral component of peroxisomal membrane(GO:0005779) |
| 0.1 | 1.2 | GO:0000506 | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506) |
| 0.1 | 0.5 | GO:0030061 | mitochondrial crista(GO:0030061) |
| 0.1 | 2.5 | GO:0031201 | SNARE complex(GO:0031201) |
| 0.1 | 3.2 | GO:0005903 | brush border(GO:0005903) cluster of actin-based cell projections(GO:0098862) |
| 0.1 | 205.2 | GO:0005634 | nucleus(GO:0005634) |
| 0.1 | 9.0 | GO:0005759 | mitochondrial matrix(GO:0005759) |
| 0.1 | 0.2 | GO:0009328 | phenylalanine-tRNA ligase complex(GO:0009328) |
| 0.1 | 1.4 | GO:0031594 | neuromuscular junction(GO:0031594) |
| 0.0 | 40.0 | GO:0005794 | Golgi apparatus(GO:0005794) |
| 0.0 | 2.3 | GO:0030176 | integral component of endoplasmic reticulum membrane(GO:0030176) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 16.8 | 151.1 | GO:0038062 | protein tyrosine kinase collagen receptor activity(GO:0038062) |
| 9.3 | 46.6 | GO:0061731 | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731) |
| 8.9 | 168.4 | GO:0001134 | transcription factor activity, transcription factor recruiting(GO:0001134) |
| 8.6 | 25.9 | GO:0005118 | sevenless binding(GO:0005118) |
| 7.1 | 42.9 | GO:0070644 | vitamin D response element binding(GO:0070644) |
| 7.0 | 27.9 | GO:0017077 | oxidative phosphorylation uncoupler activity(GO:0017077) |
| 6.6 | 19.9 | GO:0030368 | interleukin-17 receptor activity(GO:0030368) |
| 6.3 | 19.0 | GO:0071936 | coreceptor activity involved in Wnt signaling pathway(GO:0071936) |
| 5.9 | 17.7 | GO:0008330 | protein tyrosine/threonine phosphatase activity(GO:0008330) |
| 5.5 | 38.3 | GO:0070915 | lysophosphatidic acid receptor activity(GO:0070915) |
| 5.3 | 16.0 | GO:0004487 | methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487) |
| 5.2 | 57.0 | GO:0044323 | retinoic acid-responsive element binding(GO:0044323) |
| 4.9 | 19.5 | GO:0061575 | cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575) |
| 4.8 | 14.5 | GO:0030226 | apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556) |
| 4.8 | 14.4 | GO:0046592 | polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901) |
| 4.4 | 17.5 | GO:0005113 | patched binding(GO:0005113) |
| 4.3 | 25.8 | GO:0030284 | estrogen receptor activity(GO:0030284) |
| 4.1 | 32.9 | GO:0005095 | GTPase inhibitor activity(GO:0005095) |
| 3.9 | 15.4 | GO:0004415 | hyalurononglucosaminidase activity(GO:0004415) |
| 3.8 | 64.6 | GO:0070410 | co-SMAD binding(GO:0070410) |
| 3.8 | 15.0 | GO:0045131 | pre-mRNA branch point binding(GO:0045131) |
| 3.8 | 30.0 | GO:0050693 | LBD domain binding(GO:0050693) |
| 3.7 | 26.2 | GO:0048101 | calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101) |
| 3.7 | 70.4 | GO:0035497 | cAMP response element binding(GO:0035497) |
| 3.7 | 25.8 | GO:0046935 | 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935) |
| 3.4 | 17.2 | GO:0070051 | fibrinogen binding(GO:0070051) |
| 3.4 | 20.6 | GO:0061656 | SUMO conjugating enzyme activity(GO:0061656) |
| 3.4 | 202.3 | GO:0001102 | RNA polymerase II activating transcription factor binding(GO:0001102) |
| 3.4 | 10.1 | GO:0086077 | gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077) |
| 3.4 | 16.8 | GO:0050265 | RNA uridylyltransferase activity(GO:0050265) |
| 3.3 | 23.4 | GO:0046976 | histone methyltransferase activity (H3-K27 specific)(GO:0046976) |
| 3.1 | 12.6 | GO:0015410 | manganese-transporting ATPase activity(GO:0015410) |
| 3.1 | 12.4 | GO:0031721 | hemoglobin alpha binding(GO:0031721) |
| 3.0 | 12.0 | GO:0050436 | microfibril binding(GO:0050436) |
| 2.9 | 11.4 | GO:0043426 | MRF binding(GO:0043426) |
| 2.8 | 8.3 | GO:0098973 | structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973) |
| 2.8 | 22.1 | GO:0008395 | steroid hydroxylase activity(GO:0008395) |
| 2.7 | 16.2 | GO:0008597 | calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597) |
| 2.5 | 7.6 | GO:0071723 | lipopeptide binding(GO:0071723) |
| 2.5 | 22.1 | GO:0000987 | core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159) |
| 2.4 | 9.7 | GO:0038025 | reelin receptor activity(GO:0038025) |
| 2.4 | 48.4 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
| 2.4 | 9.6 | GO:0097100 | supercoiled DNA binding(GO:0097100) |
| 2.4 | 19.2 | GO:0045294 | alpha-catenin binding(GO:0045294) |
| 2.4 | 7.2 | GO:0035033 | histone deacetylase regulator activity(GO:0035033) |
| 2.4 | 40.3 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
| 2.3 | 9.2 | GO:1990460 | leptin receptor binding(GO:1990460) |
| 2.3 | 9.2 | GO:0042328 | heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328) |
| 2.3 | 32.1 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
| 2.3 | 6.9 | GO:0008527 | taste receptor activity(GO:0008527) |
| 2.2 | 6.6 | GO:0000402 | open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402) |
| 2.1 | 38.4 | GO:0016638 | oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638) |
| 2.1 | 27.7 | GO:0005522 | profilin binding(GO:0005522) |
| 2.1 | 10.4 | GO:0008172 | S-methyltransferase activity(GO:0008172) |
| 2.0 | 26.1 | GO:0030957 | Tat protein binding(GO:0030957) |
| 2.0 | 8.0 | GO:0035851 | histone deacetylase activity (H4-K16 specific)(GO:0034739) Krueppel-associated box domain binding(GO:0035851) |
| 2.0 | 12.0 | GO:0005042 | netrin receptor activity(GO:0005042) |
| 2.0 | 6.0 | GO:0047256 | beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256) |
| 1.9 | 7.6 | GO:0000832 | inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724) |
| 1.9 | 5.7 | GO:0030350 | iron-responsive element binding(GO:0030350) |
| 1.9 | 29.9 | GO:0005078 | MAP-kinase scaffold activity(GO:0005078) |
| 1.8 | 11.1 | GO:0097016 | L27 domain binding(GO:0097016) |
| 1.8 | 15.9 | GO:0050291 | sphingosine N-acyltransferase activity(GO:0050291) |
| 1.7 | 10.5 | GO:0001972 | retinoic acid binding(GO:0001972) |
| 1.7 | 6.8 | GO:0047389 | glycerophosphocholine phosphodiesterase activity(GO:0047389) |
| 1.7 | 5.1 | GO:0004335 | galactokinase activity(GO:0004335) |
| 1.7 | 13.5 | GO:0003886 | DNA (cytosine-5-)-methyltransferase activity(GO:0003886) |
| 1.7 | 18.5 | GO:0048185 | activin binding(GO:0048185) |
| 1.7 | 5.0 | GO:0019841 | retinol binding(GO:0019841) |
| 1.7 | 8.3 | GO:0008865 | fructokinase activity(GO:0008865) mannokinase activity(GO:0019158) |
| 1.6 | 8.2 | GO:0001517 | N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) |
| 1.6 | 9.8 | GO:0045322 | unmethylated CpG binding(GO:0045322) |
| 1.6 | 4.9 | GO:0050656 | 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656) |
| 1.6 | 30.6 | GO:0045295 | gamma-catenin binding(GO:0045295) |
| 1.6 | 14.2 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 1.6 | 23.6 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
| 1.5 | 4.6 | GO:0034211 | GTP-dependent protein kinase activity(GO:0034211) |
| 1.5 | 4.6 | GO:0017084 | glutamate 5-kinase activity(GO:0004349) glutamate-5-semialdehyde dehydrogenase activity(GO:0004350) delta1-pyrroline-5-carboxylate synthetase activity(GO:0017084) amino acid kinase activity(GO:0019202) |
| 1.5 | 8.9 | GO:0000155 | phosphorelay sensor kinase activity(GO:0000155) |
| 1.5 | 39.8 | GO:0031435 | mitogen-activated protein kinase kinase kinase binding(GO:0031435) |
| 1.5 | 245.3 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
| 1.5 | 11.7 | GO:0035198 | miRNA binding(GO:0035198) |
| 1.4 | 11.5 | GO:0004716 | receptor signaling protein tyrosine kinase activity(GO:0004716) |
| 1.4 | 15.3 | GO:0015347 | sodium-independent organic anion transmembrane transporter activity(GO:0015347) |
| 1.4 | 38.4 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
| 1.4 | 27.2 | GO:0004707 | MAP kinase activity(GO:0004707) |
| 1.4 | 4.1 | GO:0030249 | guanylate cyclase regulator activity(GO:0030249) |
| 1.3 | 4.0 | GO:0016174 | NAD(P)H oxidase activity(GO:0016174) |
| 1.3 | 14.5 | GO:0044390 | ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390) |
| 1.3 | 26.4 | GO:0001848 | complement binding(GO:0001848) |
| 1.3 | 13.1 | GO:0031996 | thioesterase binding(GO:0031996) |
| 1.3 | 12.9 | GO:0015245 | fatty acid transporter activity(GO:0015245) |
| 1.3 | 1.3 | GO:0030492 | hemoglobin binding(GO:0030492) |
| 1.3 | 12.6 | GO:1990247 | N6-methyladenosine-containing RNA binding(GO:1990247) |
| 1.3 | 7.6 | GO:0005087 | Ran guanyl-nucleotide exchange factor activity(GO:0005087) |
| 1.2 | 6.0 | GO:0001162 | RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162) |
| 1.2 | 8.2 | GO:0017151 | DEAD/H-box RNA helicase binding(GO:0017151) |
| 1.1 | 21.8 | GO:0004383 | guanylate cyclase activity(GO:0004383) |
| 1.1 | 4.6 | GO:0033142 | progesterone receptor binding(GO:0033142) |
| 1.1 | 39.5 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
| 1.1 | 6.7 | GO:0034046 | poly(G) binding(GO:0034046) |
| 1.1 | 1.1 | GO:0016849 | phosphorus-oxygen lyase activity(GO:0016849) |
| 1.1 | 38.6 | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) |
| 1.1 | 17.1 | GO:0008266 | poly(U) RNA binding(GO:0008266) |
| 1.0 | 74.1 | GO:0035064 | methylated histone binding(GO:0035064) |
| 1.0 | 20.7 | GO:0031078 | histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) |
| 1.0 | 3.1 | GO:0008311 | double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311) |
| 1.0 | 6.1 | GO:0016813 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813) |
| 1.0 | 19.2 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
| 1.0 | 18.0 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 1.0 | 9.0 | GO:0051011 | microtubule minus-end binding(GO:0051011) |
| 1.0 | 27.0 | GO:0051959 | dynein light intermediate chain binding(GO:0051959) |
| 1.0 | 3.0 | GO:0005124 | scavenger receptor binding(GO:0005124) |
| 1.0 | 6.8 | GO:0008568 | microtubule-severing ATPase activity(GO:0008568) |
| 1.0 | 29.9 | GO:0045182 | translation regulator activity(GO:0045182) |
| 1.0 | 34.7 | GO:0017091 | AU-rich element binding(GO:0017091) |
| 0.9 | 16.9 | GO:0031681 | G-protein beta-subunit binding(GO:0031681) |
| 0.9 | 0.9 | GO:0033680 | ATP-dependent DNA/RNA helicase activity(GO:0033680) |
| 0.9 | 11.1 | GO:0043495 | protein anchor(GO:0043495) |
| 0.9 | 2.8 | GO:0061711 | N(6)-L-threonylcarbamoyladenine synthase(GO:0061711) |
| 0.9 | 23.3 | GO:0070182 | DNA polymerase binding(GO:0070182) |
| 0.9 | 12.5 | GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861) |
| 0.9 | 98.6 | GO:0003774 | motor activity(GO:0003774) |
| 0.9 | 3.5 | GO:0032896 | palmitoyl-CoA 9-desaturase activity(GO:0032896) |
| 0.9 | 3.4 | GO:0004111 | creatine kinase activity(GO:0004111) |
| 0.9 | 3.4 | GO:0071558 | histone demethylase activity (H3-K27 specific)(GO:0071558) |
| 0.8 | 16.1 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
| 0.8 | 2.5 | GO:0071633 | dihydroceramidase activity(GO:0071633) |
| 0.8 | 14.0 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
| 0.8 | 6.5 | GO:0097642 | calcitonin family receptor activity(GO:0097642) |
| 0.8 | 34.3 | GO:0032266 | phosphatidylinositol-3-phosphate binding(GO:0032266) |
| 0.8 | 4.0 | GO:0015186 | L-glutamine transmembrane transporter activity(GO:0015186) |
| 0.8 | 6.3 | GO:0008417 | fucosyltransferase activity(GO:0008417) |
| 0.8 | 17.3 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
| 0.8 | 3.9 | GO:0030144 | alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144) |
| 0.8 | 8.3 | GO:0016274 | arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274) |
| 0.8 | 6.8 | GO:0061133 | endopeptidase activator activity(GO:0061133) |
| 0.7 | 9.6 | GO:0001222 | transcription corepressor binding(GO:0001222) |
| 0.7 | 23.5 | GO:0051059 | NF-kappaB binding(GO:0051059) |
| 0.7 | 4.4 | GO:1990189 | peptide-serine-N-acetyltransferase activity(GO:1990189) |
| 0.7 | 2.1 | GO:0031752 | D5 dopamine receptor binding(GO:0031752) |
| 0.7 | 378.0 | GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) |
| 0.7 | 4.7 | GO:0061578 | Lys63-specific deubiquitinase activity(GO:0061578) |
| 0.7 | 8.6 | GO:0070513 | death domain binding(GO:0070513) |
| 0.7 | 2.7 | GO:0010521 | telomerase inhibitor activity(GO:0010521) |
| 0.7 | 2.0 | GO:0001069 | regulatory region RNA binding(GO:0001069) |
| 0.6 | 25.1 | GO:0005109 | frizzled binding(GO:0005109) |
| 0.6 | 5.0 | GO:0002162 | dystroglycan binding(GO:0002162) |
| 0.6 | 35.6 | GO:0003714 | transcription corepressor activity(GO:0003714) |
| 0.6 | 18.2 | GO:0042054 | histone methyltransferase activity(GO:0042054) |
| 0.6 | 1.2 | GO:1990269 | RNA polymerase II C-terminal domain phosphoserine binding(GO:1990269) |
| 0.6 | 6.0 | GO:0001727 | lipid kinase activity(GO:0001727) |
| 0.6 | 1.8 | GO:0050510 | N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510) |
| 0.6 | 3.5 | GO:0003831 | beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831) |
| 0.6 | 1.7 | GO:0005344 | oxygen transporter activity(GO:0005344) |
| 0.6 | 3.5 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
| 0.6 | 2.8 | GO:0043559 | insulin binding(GO:0043559) |
| 0.6 | 10.1 | GO:0050321 | tau-protein kinase activity(GO:0050321) |
| 0.6 | 7.8 | GO:0032794 | GTPase activating protein binding(GO:0032794) |
| 0.6 | 8.3 | GO:0050431 | transforming growth factor beta binding(GO:0050431) |
| 0.5 | 13.1 | GO:0004602 | glutathione peroxidase activity(GO:0004602) |
| 0.5 | 1.1 | GO:0051021 | GDP-dissociation inhibitor binding(GO:0051021) |
| 0.5 | 2.1 | GO:0003883 | CTP synthase activity(GO:0003883) |
| 0.5 | 3.6 | GO:0016618 | hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267) |
| 0.5 | 6.1 | GO:0055103 | ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106) |
| 0.5 | 15.2 | GO:0030332 | cyclin binding(GO:0030332) |
| 0.5 | 1.5 | GO:0004357 | glutamate-cysteine ligase activity(GO:0004357) |
| 0.5 | 4.9 | GO:0008327 | methyl-CpG binding(GO:0008327) |
| 0.4 | 7.1 | GO:0017166 | vinculin binding(GO:0017166) |
| 0.4 | 0.9 | GO:0019966 | interleukin-1 binding(GO:0019966) |
| 0.4 | 2.1 | GO:0005052 | peroxisome matrix targeting signal-1 binding(GO:0005052) |
| 0.4 | 5.5 | GO:0004402 | histone acetyltransferase activity(GO:0004402) |
| 0.4 | 12.9 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
| 0.4 | 17.3 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.4 | 2.1 | GO:1990825 | sequence-specific mRNA binding(GO:1990825) |
| 0.4 | 4.8 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
| 0.4 | 26.9 | GO:0004722 | protein serine/threonine phosphatase activity(GO:0004722) |
| 0.4 | 8.3 | GO:0004601 | peroxidase activity(GO:0004601) |
| 0.4 | 2.3 | GO:0070097 | delta-catenin binding(GO:0070097) |
| 0.4 | 12.1 | GO:0051183 | vitamin transporter activity(GO:0051183) |
| 0.4 | 12.1 | GO:0042169 | SH2 domain binding(GO:0042169) |
| 0.4 | 1.1 | GO:0008109 | N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109) |
| 0.4 | 1.5 | GO:0004832 | valine-tRNA ligase activity(GO:0004832) |
| 0.4 | 17.0 | GO:0004712 | protein serine/threonine/tyrosine kinase activity(GO:0004712) |
| 0.4 | 1.4 | GO:0038036 | sphingosine-1-phosphate receptor activity(GO:0038036) |
| 0.4 | 4.9 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
| 0.4 | 6.0 | GO:0009982 | pseudouridine synthase activity(GO:0009982) |
| 0.3 | 6.0 | GO:0005044 | scavenger receptor activity(GO:0005044) |
| 0.3 | 2.6 | GO:0004439 | phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439) |
| 0.3 | 2.9 | GO:0031491 | nucleosome binding(GO:0031491) |
| 0.3 | 7.2 | GO:0004697 | protein kinase C activity(GO:0004697) |
| 0.3 | 5.5 | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) |
| 0.3 | 5.8 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) |
| 0.3 | 4.1 | GO:0008143 | poly(A) binding(GO:0008143) |
| 0.3 | 8.8 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
| 0.3 | 0.9 | GO:0004127 | cytidylate kinase activity(GO:0004127) uridylate kinase activity(GO:0009041) |
| 0.3 | 376.8 | GO:0003677 | DNA binding(GO:0003677) |
| 0.3 | 4.5 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.3 | 4.7 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
| 0.3 | 0.9 | GO:0008432 | JUN kinase binding(GO:0008432) |
| 0.3 | 2.0 | GO:0015288 | porin activity(GO:0015288) |
| 0.3 | 2.8 | GO:0015037 | peptide disulfide oxidoreductase activity(GO:0015037) |
| 0.3 | 0.5 | GO:0042610 | CD8 receptor binding(GO:0042610) |
| 0.3 | 0.8 | GO:0071532 | ankyrin repeat binding(GO:0071532) |
| 0.3 | 16.1 | GO:0019843 | rRNA binding(GO:0019843) |
| 0.3 | 2.2 | GO:0050692 | DBD domain binding(GO:0050692) |
| 0.3 | 5.9 | GO:0042605 | peptide antigen binding(GO:0042605) |
| 0.3 | 3.2 | GO:0042288 | MHC class I protein binding(GO:0042288) |
| 0.3 | 4.5 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
| 0.3 | 2.0 | GO:0035374 | chondroitin sulfate binding(GO:0035374) |
| 0.3 | 2.3 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
| 0.2 | 4.8 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.2 | 12.4 | GO:0051287 | NAD binding(GO:0051287) |
| 0.2 | 3.6 | GO:0046527 | glucosyltransferase activity(GO:0046527) |
| 0.2 | 1.8 | GO:0050733 | RS domain binding(GO:0050733) |
| 0.2 | 4.0 | GO:0034237 | protein kinase A regulatory subunit binding(GO:0034237) |
| 0.2 | 8.4 | GO:0008146 | sulfotransferase activity(GO:0008146) |
| 0.2 | 1.3 | GO:0016300 | tRNA (uracil) methyltransferase activity(GO:0016300) |
| 0.2 | 1.0 | GO:0004563 | beta-N-acetylhexosaminidase activity(GO:0004563) |
| 0.2 | 1.7 | GO:0030306 | ADP-ribosylation factor binding(GO:0030306) |
| 0.2 | 3.1 | GO:0004190 | aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001) |
| 0.2 | 1.4 | GO:0019213 | deacetylase activity(GO:0019213) |
| 0.2 | 10.7 | GO:0008186 | RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186) |
| 0.2 | 2.5 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
| 0.2 | 1.0 | GO:0002054 | nucleobase binding(GO:0002054) |
| 0.2 | 1.9 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
| 0.2 | 0.5 | GO:0070736 | protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736) |
| 0.2 | 0.6 | GO:0001602 | pancreatic polypeptide receptor activity(GO:0001602) |
| 0.1 | 6.1 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
| 0.1 | 5.2 | GO:0020037 | heme binding(GO:0020037) |
| 0.1 | 1.5 | GO:0003823 | antigen binding(GO:0003823) |
| 0.1 | 5.3 | GO:0005484 | SNAP receptor activity(GO:0005484) |
| 0.1 | 0.2 | GO:0003705 | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705) |
| 0.1 | 1.2 | GO:0017176 | phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176) |
| 0.1 | 0.7 | GO:0005138 | interleukin-6 receptor binding(GO:0005138) |
| 0.1 | 1.5 | GO:0008253 | 5'-nucleotidase activity(GO:0008253) |
| 0.1 | 7.0 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.1 | 2.9 | GO:0031369 | translation initiation factor binding(GO:0031369) |
| 0.1 | 8.1 | GO:0003682 | chromatin binding(GO:0003682) |
| 0.1 | 6.3 | GO:0043130 | ubiquitin binding(GO:0043130) |
| 0.1 | 0.8 | GO:0009922 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
| 0.1 | 1.4 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 0.1 | 5.6 | GO:0003713 | transcription coactivator activity(GO:0003713) |
| 0.1 | 10.6 | GO:0008134 | transcription factor binding(GO:0008134) |
| 0.1 | 16.3 | GO:0045296 | cadherin binding(GO:0045296) |
| 0.1 | 0.4 | GO:0004984 | olfactory receptor activity(GO:0004984) |
| 0.1 | 3.6 | GO:0004843 | thiol-dependent ubiquitin-specific protease activity(GO:0004843) |
| 0.1 | 0.9 | GO:0030544 | Hsp70 protein binding(GO:0030544) |
| 0.1 | 5.1 | GO:0004860 | protein kinase inhibitor activity(GO:0004860) |
| 0.1 | 0.4 | GO:0047184 | 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184) |
| 0.1 | 0.2 | GO:0036468 | aromatic-L-amino-acid decarboxylase activity(GO:0004058) L-dopa decarboxylase activity(GO:0036468) |
| 0.1 | 4.1 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.0 | 0.9 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
| 0.0 | 1.2 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
| 0.0 | 0.2 | GO:0004719 | protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719) |
| 0.0 | 0.1 | GO:0046997 | sarcosine dehydrogenase activity(GO:0008480) oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997) |
| 0.0 | 1.1 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.0 | 0.3 | GO:0016312 | inositol bisphosphate phosphatase activity(GO:0016312) |
| 0.0 | 1.0 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 0.0 | 2.1 | GO:0008168 | methyltransferase activity(GO:0008168) |
| 0.0 | 0.2 | GO:0004826 | phenylalanine-tRNA ligase activity(GO:0004826) |
| 0.0 | 0.2 | GO:0008440 | inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) |
| 0.0 | 1.8 | GO:0051082 | unfolded protein binding(GO:0051082) |
| 0.0 | 0.9 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.0 | 0.7 | GO:0016831 | carboxy-lyase activity(GO:0016831) |
| 0.0 | 22.0 | GO:0003723 | RNA binding(GO:0003723) |
| 0.0 | 3.2 | GO:0003700 | nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700) |
| 0.0 | 0.4 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.0 | 0.1 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.6 | 37.0 | SA_REG_CASCADE_OF_CYCLIN_EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 2.3 | 23.3 | ST_FAS_SIGNALING_PATHWAY | Fas Signaling Pathway |
| 2.0 | 32.7 | PID_ANTHRAX_PATHWAY | Cellular roles of Anthrax toxin |
| 2.0 | 117.3 | PID_IL12_2PATHWAY | IL12-mediated signaling events |
| 2.0 | 19.9 | PID_FGF_PATHWAY | FGF signaling pathway |
| 1.3 | 33.2 | PID_P38_MKK3_6PATHWAY | p38 MAPK signaling pathway |
| 1.3 | 59.4 | PID_AURORA_B_PATHWAY | Aurora B signaling |
| 1.3 | 58.8 | PID_NETRIN_PATHWAY | Netrin-mediated signaling events |
| 1.2 | 17.8 | PID_ERB_GENOMIC_PATHWAY | Validated nuclear estrogen receptor beta network |
| 1.1 | 11.4 | PID_AJDISS_2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
| 1.1 | 81.6 | PID_CMYB_PATHWAY | C-MYB transcription factor network |
| 1.0 | 83.7 | PID_E2F_PATHWAY | E2F transcription factor network |
| 1.0 | 54.6 | PID_ECADHERIN_NASCENT_AJ_PATHWAY | E-cadherin signaling in the nascent adherens junction |
| 1.0 | 18.4 | PID_RANBP2_PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
| 1.0 | 8.2 | PID_ALK2_PATHWAY | ALK2 signaling events |
| 1.0 | 5.0 | PID_RETINOIC_ACID_PATHWAY | Retinoic acid receptors-mediated signaling |
| 1.0 | 27.2 | PID_AMB2_NEUTROPHILS_PATHWAY | amb2 Integrin signaling |
| 1.0 | 40.6 | PID_THROMBIN_PAR1_PATHWAY | PAR1-mediated thrombin signaling events |
| 0.9 | 56.4 | PID_HEDGEHOG_GLI_PATHWAY | Hedgehog signaling events mediated by Gli proteins |
| 0.9 | 29.4 | PID_HIF2PATHWAY | HIF-2-alpha transcription factor network |
| 0.9 | 47.5 | PID_SMAD2_3NUCLEAR_PATHWAY | Regulation of nuclear SMAD2/3 signaling |
| 0.9 | 22.0 | PID_TCR_CALCIUM_PATHWAY | Calcium signaling in the CD4+ TCR pathway |
| 0.9 | 27.9 | PID_HNF3B_PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.9 | 10.4 | PID_VEGF_VEGFR_PATHWAY | VEGF and VEGFR signaling network |
| 0.8 | 16.7 | ST_ERK1_ERK2_MAPK_PATHWAY | ERK1/ERK2 MAPK Pathway |
| 0.8 | 28.3 | PID_RXR_VDR_PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
| 0.8 | 5.5 | PID_PS1_PATHWAY | Presenilin action in Notch and Wnt signaling |
| 0.8 | 52.8 | PID_NOTCH_PATHWAY | Notch signaling pathway |
| 0.8 | 12.9 | PID_MYC_PATHWAY | C-MYC pathway |
| 0.7 | 29.5 | PID_HDAC_CLASSII_PATHWAY | Signaling events mediated by HDAC Class II |
| 0.7 | 1.4 | PID_S1P_S1P2_PATHWAY | S1P2 pathway |
| 0.7 | 21.5 | PID_DELTA_NP63_PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.6 | 3.2 | PID_TCR_JNK_PATHWAY | JNK signaling in the CD4+ TCR pathway |
| 0.6 | 23.6 | PID_AP1_PATHWAY | AP-1 transcription factor network |
| 0.6 | 20.1 | ST_WNT_BETA_CATENIN_PATHWAY | Wnt/beta-catenin Pathway |
| 0.6 | 34.7 | WNT_SIGNALING | Genes related to Wnt-mediated signal transduction |
| 0.6 | 31.6 | PID_BETA_CATENIN_NUC_PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
| 0.6 | 6.0 | PID_LYSOPHOSPHOLIPID_PATHWAY | LPA receptor mediated events |
| 0.6 | 11.3 | ST_G_ALPHA_S_PATHWAY | G alpha s Pathway |
| 0.6 | 3.4 | PID_SYNDECAN_3_PATHWAY | Syndecan-3-mediated signaling events |
| 0.5 | 23.5 | SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES | Genes related to the insulin receptor pathway |
| 0.5 | 1.1 | PID_IL8_CXCR1_PATHWAY | IL8- and CXCR1-mediated signaling events |
| 0.5 | 10.6 | PID_CXCR3_PATHWAY | CXCR3-mediated signaling events |
| 0.5 | 27.4 | PID_CASPASE_PATHWAY | Caspase cascade in apoptosis |
| 0.5 | 6.6 | PID_RAC1_PATHWAY | RAC1 signaling pathway |
| 0.5 | 9.0 | PID_MAPK_TRK_PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
| 0.5 | 14.0 | PID_HNF3A_PATHWAY | FOXA1 transcription factor network |
| 0.5 | 7.4 | PID_ERBB2_ERBB3_PATHWAY | ErbB2/ErbB3 signaling events |
| 0.4 | 6.3 | PID_P38_MK2_PATHWAY | p38 signaling mediated by MAPKAP kinases |
| 0.4 | 12.2 | PID_LIS1_PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 0.4 | 9.4 | PID_ERBB4_PATHWAY | ErbB4 signaling events |
| 0.4 | 15.5 | PID_ARF6_TRAFFICKING_PATHWAY | Arf6 trafficking events |
| 0.3 | 44.6 | NABA_ECM_REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.3 | 13.0 | PID_ERBB1_DOWNSTREAM_PATHWAY | ErbB1 downstream signaling |
| 0.3 | 9.2 | PID_FAK_PATHWAY | Signaling events mediated by focal adhesion kinase |
| 0.3 | 4.0 | PID_CD40_PATHWAY | CD40/CD40L signaling |
| 0.3 | 8.0 | PID_HDAC_CLASSI_PATHWAY | Signaling events mediated by HDAC Class I |
| 0.3 | 17.9 | PID_MYC_ACTIV_PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.3 | 12.9 | PID_PLK1_PATHWAY | PLK1 signaling events |
| 0.2 | 9.5 | PID_P53_REGULATION_PATHWAY | p53 pathway |
| 0.2 | 3.4 | PID_HES_HEY_PATHWAY | Notch-mediated HES/HEY network |
| 0.2 | 3.4 | PID_CERAMIDE_PATHWAY | Ceramide signaling pathway |
| 0.2 | 3.5 | PID_AR_TF_PATHWAY | Regulation of Androgen receptor activity |
| 0.2 | 1.9 | PID_TRAIL_PATHWAY | TRAIL signaling pathway |
| 0.1 | 2.3 | PID_ALPHA_SYNUCLEIN_PATHWAY | Alpha-synuclein signaling |
| 0.1 | 1.9 | PID_FOXO_PATHWAY | FoxO family signaling |
| 0.1 | 3.2 | SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.1 | 13.1 | NABA_ECM_AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.1 | 1.3 | PID_HEDGEHOG_2PATHWAY | Signaling events mediated by the Hedgehog family |
| 0.1 | 1.2 | PID_CIRCADIAN_PATHWAY | Circadian rhythm pathway |
| 0.1 | 2.7 | PID_CDC42_REG_PATHWAY | Regulation of CDC42 activity |
| 0.1 | 0.8 | PID_RB_1PATHWAY | Regulation of retinoblastoma protein |
| 0.0 | 0.6 | PID_AURORA_A_PATHWAY | Aurora A signaling |
| 0.0 | 0.2 | ST_PAC1_RECEPTOR_PATHWAY | PAC1 Receptor Pathway |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 6.3 | 193.8 | REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
| 4.3 | 34.5 | REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol |
| 3.6 | 32.3 | REACTOME_P2Y_RECEPTORS | Genes involved in P2Y receptors |
| 3.1 | 46.6 | REACTOME_G1_S_SPECIFIC_TRANSCRIPTION | Genes involved in G1/S-Specific Transcription |
| 3.0 | 114.1 | REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION | Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription |
| 2.9 | 17.1 | REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE | Genes involved in Translocation of ZAP-70 to Immunological synapse |
| 2.5 | 20.2 | REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE | Genes involved in Regulation of Insulin Secretion by Acetylcholine |
| 2.5 | 29.7 | REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX | Genes involved in CDC6 association with the ORC:origin complex |
| 2.1 | 25.8 | REACTOME_IL_7_SIGNALING | Genes involved in Interleukin-7 signaling |
| 1.9 | 40.4 | REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION | Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) |
| 1.9 | 26.9 | REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES | Genes involved in Generation of second messenger molecules |
| 1.8 | 36.5 | REACTOME_REGULATION_OF_KIT_SIGNALING | Genes involved in Regulation of KIT signaling |
| 1.8 | 46.5 | REACTOME_OTHER_SEMAPHORIN_INTERACTIONS | Genes involved in Other semaphorin interactions |
| 1.5 | 15.4 | REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
| 1.5 | 15.0 | REACTOME_INTRINSIC_PATHWAY | Genes involved in Intrinsic Pathway |
| 1.5 | 50.4 | REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT | Genes involved in Regulation of beta-cell development |
| 1.4 | 6.9 | REACTOME_HYALURONAN_METABOLISM | Genes involved in Hyaluronan metabolism |
| 1.2 | 18.5 | REACTOME_SIGNALING_BY_NODAL | Genes involved in Signaling by NODAL |
| 1.2 | 13.1 | REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR | Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor |
| 1.2 | 8.3 | REACTOME_DSCAM_INTERACTIONS | Genes involved in DSCAM interactions |
| 1.1 | 17.1 | REACTOME_SIGNALLING_TO_P38_VIA_RIT_AND_RIN | Genes involved in Signalling to p38 via RIT and RIN |
| 1.1 | 42.4 | REACTOME_MYOGENESIS | Genes involved in Myogenesis |
| 1.1 | 14.4 | REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS | Genes involved in Role of DCC in regulating apoptosis |
| 1.1 | 29.8 | REACTOME_RNA_POL_III_TRANSCRIPTION_TERMINATION | Genes involved in RNA Polymerase III Transcription Termination |
| 1.1 | 10.8 | REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER | Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter |
| 1.1 | 10.6 | REACTOME_ACTIVATION_OF_RAC | Genes involved in Activation of Rac |
| 1.0 | 16.1 | REACTOME_METABOLISM_OF_POLYAMINES | Genes involved in Metabolism of polyamines |
| 1.0 | 14.8 | REACTOME_ERKS_ARE_INACTIVATED | Genes involved in ERKs are inactivated |
| 1.0 | 26.4 | REACTOME_KINESINS | Genes involved in Kinesins |
| 0.9 | 12.9 | REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
| 0.9 | 17.2 | REACTOME_CONVERSION_FROM_APC_C_CDC20_TO_APC_C_CDH1_IN_LATE_ANAPHASE | Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase |
| 0.9 | 10.4 | REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |
| 0.8 | 7.5 | REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES | Genes involved in Recruitment of NuMA to mitotic centrosomes |
| 0.8 | 33.3 | REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS | Genes involved in O-linked glycosylation of mucins |
| 0.8 | 7.2 | REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY | Genes involved in Notch-HLH transcription pathway |
| 0.8 | 22.0 | REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
| 0.8 | 25.1 | REACTOME_SMOOTH_MUSCLE_CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.7 | 80.8 | REACTOME_MEIOSIS | Genes involved in Meiosis |
| 0.7 | 14.5 | REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS | Genes involved in ABCA transporters in lipid homeostasis |
| 0.7 | 17.8 | REACTOME_TIGHT_JUNCTION_INTERACTIONS | Genes involved in Tight junction interactions |
| 0.7 | 7.6 | REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.7 | 13.8 | REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
| 0.6 | 10.5 | REACTOME_DESTABILIZATION_OF_MRNA_BY_TRISTETRAPROLIN_TTP | Genes involved in Destabilization of mRNA by Tristetraprolin (TTP) |
| 0.6 | 6.6 | REACTOME_ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING | Genes involved in Advanced glycosylation endproduct receptor signaling |
| 0.6 | 21.3 | REACTOME_NETRIN1_SIGNALING | Genes involved in Netrin-1 signaling |
| 0.5 | 6.3 | REACTOME_GAP_JUNCTION_ASSEMBLY | Genes involved in Gap junction assembly |
| 0.5 | 22.0 | REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.5 | 18.7 | REACTOME_THROMBIN_SIGNALLING_THROUGH_PROTEINASE_ACTIVATED_RECEPTORS_PARS | Genes involved in Thrombin signalling through proteinase activated receptors (PARs) |
| 0.5 | 6.0 | REACTOME_G0_AND_EARLY_G1 | Genes involved in G0 and Early G1 |
| 0.5 | 11.4 | REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS | Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus |
| 0.5 | 3.9 | REACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS | Genes involved in p130Cas linkage to MAPK signaling for integrins |
| 0.4 | 9.7 | REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
| 0.4 | 11.0 | REACTOME_SIGNALING_BY_HIPPO | Genes involved in Signaling by Hippo |
| 0.4 | 2.8 | REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_2_PROMOTER | Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter |
| 0.4 | 26.5 | REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION | Genes involved in Factors involved in megakaryocyte development and platelet production |
| 0.4 | 7.8 | REACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING | Genes involved in Pre-NOTCH Expression and Processing |
| 0.3 | 12.9 | REACTOME_INTERFERON_ALPHA_BETA_SIGNALING | Genes involved in Interferon alpha/beta signaling |
| 0.3 | 2.8 | REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS | Genes involved in Membrane binding and targetting of GAG proteins |
| 0.3 | 4.8 | REACTOME_TRANSCRIPTIONAL_ACTIVITY_OF_SMAD2_SMAD3_SMAD4_HETEROTRIMER | Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer |
| 0.3 | 13.0 | REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING | Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening |
| 0.3 | 14.5 | REACTOME_CIRCADIAN_CLOCK | Genes involved in Circadian Clock |
| 0.3 | 26.1 | REACTOME_RESPIRATORY_ELECTRON_TRANSPORT_ATP_SYNTHESIS_BY_CHEMIOSMOTIC_COUPLING_AND_HEAT_PRODUCTION_BY_UNCOUPLING_PROTEINS_ | Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. |
| 0.3 | 3.1 | REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY | Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway |
| 0.3 | 2.5 | REACTOME_TRYPTOPHAN_CATABOLISM | Genes involved in Tryptophan catabolism |
| 0.3 | 4.7 | REACTOME_ZINC_TRANSPORTERS | Genes involved in Zinc transporters |
| 0.3 | 4.0 | REACTOME_KERATAN_SULFATE_BIOSYNTHESIS | Genes involved in Keratan sulfate biosynthesis |
| 0.3 | 5.4 | REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE | Genes involved in Glutamate Neurotransmitter Release Cycle |
| 0.2 | 2.0 | REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS | Genes involved in Passive Transport by Aquaporins |
| 0.2 | 5.5 | REACTOME_PLATELET_AGGREGATION_PLUG_FORMATION | Genes involved in Platelet Aggregation (Plug Formation) |
| 0.2 | 7.1 | REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES | Genes involved in Antiviral mechanism by IFN-stimulated genes |
| 0.2 | 49.2 | REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
| 0.2 | 6.9 | REACTOME_MRNA_SPLICING_MINOR_PATHWAY | Genes involved in mRNA Splicing - Minor Pathway |
| 0.2 | 4.7 | REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING | Genes involved in Negative regulators of RIG-I/MDA5 signaling |
| 0.2 | 3.5 | REACTOME_RNA_POL_I_TRANSCRIPTION | Genes involved in RNA Polymerase I Transcription |
| 0.2 | 9.6 | REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
| 0.2 | 8.7 | REACTOME_PHASE_II_CONJUGATION | Genes involved in Phase II conjugation |
| 0.1 | 1.5 | REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM | Genes involved in Abacavir transport and metabolism |
| 0.1 | 2.6 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE | Genes involved in Synthesis of PIPs at the Golgi membrane |
| 0.1 | 1.9 | REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS | Genes involved in Extrinsic Pathway for Apoptosis |
| 0.1 | 4.7 | REACTOME_MRNA_3_END_PROCESSING | Genes involved in mRNA 3'-end processing |
| 0.1 | 0.7 | REACTOME_IL_6_SIGNALING | Genes involved in Interleukin-6 signaling |
| 0.1 | 8.3 | REACTOME_DNA_REPAIR | Genes involved in DNA Repair |
| 0.1 | 5.3 | REACTOME_HOST_INTERACTIONS_OF_HIV_FACTORS | Genes involved in Host Interactions of HIV factors |
| 0.1 | 1.0 | REACTOME_PYRIMIDINE_CATABOLISM | Genes involved in Pyrimidine catabolism |
| 0.1 | 4.6 | REACTOME_GLUCOSE_TRANSPORT | Genes involved in Glucose transport |
| 0.1 | 0.3 | REACTOME_DESTABILIZATION_OF_MRNA_BY_KSRP | Genes involved in Destabilization of mRNA by KSRP |
| 0.1 | 1.3 | REACTOME_STEROID_HORMONES | Genes involved in Steroid hormones |
| 0.1 | 2.1 | REACTOME_SYNTHESIS_OF_PC | Genes involved in Synthesis of PC |
| 0.1 | 1.1 | REACTOME_METABOLISM_OF_NON_CODING_RNA | Genes involved in Metabolism of non-coding RNA |
| 0.1 | 5.7 | REACTOME_MITOTIC_PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.1 | 1.6 | REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS | Genes involved in G alpha (z) signalling events |
| 0.1 | 1.2 | REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION | Genes involved in Mitochondrial tRNA aminoacylation |
| 0.1 | 1.2 | REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI | Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) |
| 0.0 | 3.7 | REACTOME_GLYCEROPHOSPHOLIPID_BIOSYNTHESIS | Genes involved in Glycerophospholipid biosynthesis |
| 0.0 | 2.6 | REACTOME_GLYCOSAMINOGLYCAN_METABOLISM | Genes involved in Glycosaminoglycan metabolism |
| 0.0 | 0.5 | REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION | Genes involved in Amino acid synthesis and interconversion (transamination) |
| 0.0 | 0.3 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_LATE_ENDOSOME_MEMBRANE | Genes involved in Synthesis of PIPs at the late endosome membrane |
| 0.0 | 0.7 | REACTOME_INTERFERON_SIGNALING | Genes involved in Interferon Signaling |
| 0.0 | 0.5 | REACTOME_PYRUVATE_METABOLISM | Genes involved in Pyruvate metabolism |
| 0.0 | 0.2 | REACTOME_AMINE_DERIVED_HORMONES | Genes involved in Amine-derived hormones |
| 0.0 | 2.1 | REACTOME_DIABETES_PATHWAYS | Genes involved in Diabetes pathways |
| 0.0 | 0.2 | REACTOME_G1_PHASE | Genes involved in G1 Phase |
