Motif ID: Sox30

Z-value: 0.352


Transcription factors associated with Sox30:

Gene SymbolEntrez IDGene Name
Sox30 ENSMUSG00000040489.5 Sox30



Activity profile for motif Sox30.

activity profile for motif Sox30


Sorted Z-values histogram for motif Sox30

Sorted Z-values for motif Sox30



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox30

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_23248264 7.427 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr1_+_135729147 2.715 ENSMUST00000027677.7
 Csrp1
cysteine and glycine-rich protein 1
chr18_-_88927447 1.876 ENSMUST00000147313.1
 Socs6
suppressor of cytokine signaling 6
chr6_-_12749193 1.844 ENSMUST00000046121.6
ENSMUST00000172356.1
 Thsd7a

thrombospondin, type I, domain containing 7A

chr5_+_92809372 1.837 ENSMUST00000113054.2
 Shroom3
shroom family member 3
chrX_-_134161928 1.587 ENSMUST00000033611.4
 Xkrx
X Kell blood group precursor related X linked
chr9_+_7764041 1.530 ENSMUST00000052865.9
 Tmem123
transmembrane protein 123
chr12_-_99883429 1.444 ENSMUST00000046485.3
 Efcab11
EF-hand calcium binding domain 11
chr10_-_62792243 1.337 ENSMUST00000020268.5
 Ccar1
cell division cycle and apoptosis regulator 1
chr3_+_34649987 1.119 ENSMUST00000099151.2
 Sox2
SRY-box containing gene 2
chr4_-_115133977 1.032 ENSMUST00000051400.7
 Cyp4x1
cytochrome P450, family 4, subfamily x, polypeptide 1
chr9_-_72111651 0.936 ENSMUST00000185117.1
 Tcf12
transcription factor 12
chr1_+_10056922 0.872 ENSMUST00000149214.1
 Cspp1
centrosome and spindle pole associated protein 1
chr6_-_3494587 0.807 ENSMUST00000049985.8
 Hepacam2
HEPACAM family member 2
chr13_-_102958084 0.757 ENSMUST00000099202.3
ENSMUST00000172264.1
 Mast4

microtubule associated serine/threonine kinase family member 4

chr1_+_37997975 0.690 ENSMUST00000027252.7
 Eif5b
eukaryotic translation initiation factor 5B
chr9_-_103480328 0.684 ENSMUST00000124310.2
 Bfsp2
beaded filament structural protein 2, phakinin
chr10_+_17796256 0.643 ENSMUST00000037964.6
 Txlnb
taxilin beta
chr11_+_21091291 0.571 ENSMUST00000093290.5
 Peli1
pellino 1
chr4_+_137993445 0.539 ENSMUST00000105831.2
ENSMUST00000084214.5
 Eif4g3

eukaryotic translation initiation factor 4 gamma, 3

chr17_-_79355082 0.490 ENSMUST00000068958.7
 Cdc42ep3
CDC42 effector protein (Rho GTPase binding) 3
chr2_-_65567505 0.450 ENSMUST00000100069.2
 Scn3a
sodium channel, voltage-gated, type III, alpha
chr2_-_65567465 0.440 ENSMUST00000066432.5
 Scn3a
sodium channel, voltage-gated, type III, alpha
chr2_-_181599128 0.422 ENSMUST00000060173.8
 Samd10
sterile alpha motif domain containing 10
chr13_-_97747373 0.408 ENSMUST00000123535.1
 5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr9_-_60511003 0.387 ENSMUST00000098660.3
 Thsd4
thrombospondin, type I, domain containing 4
chr10_-_24836165 0.386 ENSMUST00000020169.7
 Enpp3
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr7_+_90426312 0.383 ENSMUST00000061391.7
 Ccdc89
coiled-coil domain containing 89
chr18_-_62756275 0.378 ENSMUST00000067450.1
ENSMUST00000048109.5
 2700046A07Rik

RIKEN cDNA 2700046A07 gene

chr7_+_127800604 0.353 ENSMUST00000046863.5
ENSMUST00000106272.1
ENSMUST00000139068.1
 Hsd3b7


hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7


chr4_+_83417715 0.340 ENSMUST00000030206.3
ENSMUST00000071544.4
 Snapc3

small nuclear RNA activating complex, polypeptide 3

chr4_+_137993016 0.328 ENSMUST00000105830.2
ENSMUST00000084215.5
ENSMUST00000058133.3
ENSMUST00000139759.1
 Eif4g3



eukaryotic translation initiation factor 4 gamma, 3



chr10_-_53647080 0.326 ENSMUST00000169866.1
 Fam184a
family with sequence similarity 184, member A
chr11_+_3983704 0.320 ENSMUST00000063004.7
 Gal3st1
galactose-3-O-sulfotransferase 1
chr15_+_100038635 0.320 ENSMUST00000100203.3
 Dip2b
DIP2 disco-interacting protein 2 homolog B (Drosophila)
chr4_+_109343029 0.295 ENSMUST00000030281.5
 Eps15
epidermal growth factor receptor pathway substrate 15
chr14_+_116925379 0.262 ENSMUST00000088483.3
 Gpc6
glypican 6
chr10_+_90829538 0.248 ENSMUST00000179694.2
 Anks1b
ankyrin repeat and sterile alpha motif domain containing 1B
chr19_-_56822161 0.248 ENSMUST00000118592.1
 A630007B06Rik
RIKEN cDNA A630007B06 gene
chr11_+_3983636 0.230 ENSMUST00000078757.1
 Gal3st1
galactose-3-O-sulfotransferase 1
chr13_-_56135629 0.227 ENSMUST00000016081.6
ENSMUST00000045788.7
 H2afy

H2A histone family, member Y

chr12_+_8674129 0.224 ENSMUST00000111123.2
ENSMUST00000178015.1
ENSMUST00000020915.3
 Pum2


pumilio 2 (Drosophila)


chr13_-_97747399 0.214 ENSMUST00000144993.1
 5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr4_+_48585135 0.184 ENSMUST00000030032.6
 Tmeff1
transmembrane protein with EGF-like and two follistatin-like domains 1
chr19_+_44293676 0.164 ENSMUST00000026221.5
 Scd2
stearoyl-Coenzyme A desaturase 2
chr12_+_8674224 0.145 ENSMUST00000111122.2
 Pum2
pumilio 2 (Drosophila)
chr11_+_51261719 0.140 ENSMUST00000130641.1
 Clk4
CDC like kinase 4
chr9_+_74976096 0.138 ENSMUST00000081746.5
 Fam214a
family with sequence similarity 214, member A
chr10_+_90829409 0.118 ENSMUST00000182202.1
ENSMUST00000182966.1
 Anks1b

ankyrin repeat and sterile alpha motif domain containing 1B

chr5_+_14514918 0.081 ENSMUST00000030691.10
ENSMUST00000182407.1
 Pclo

piccolo (presynaptic cytomatrix protein)

chr2_-_119787504 0.080 ENSMUST00000110793.1
ENSMUST00000099529.2
ENSMUST00000048493.5
 Rpap1


RNA polymerase II associated protein 1


chr5_-_62765618 0.077 ENSMUST00000159470.1
 Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr4_-_119190005 0.055 ENSMUST00000138395.1
ENSMUST00000156746.1
 Ermap

erythroblast membrane-associated protein

chr3_-_127837419 0.041 ENSMUST00000051737.6
 Ap1ar
adaptor-related protein complex 1 associated regulatory protein
chr4_+_134396320 0.040 ENSMUST00000105869.2
 Pafah2
platelet-activating factor acetylhydrolase 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 7.4 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.2 1.1 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.2 0.9 GO:0046684 response to pyrethroid(GO:0046684)
0.1 0.9 GO:0060903 positive regulation of meiosis I(GO:0060903)
0.1 0.2 GO:0033128 negative regulation of histone phosphorylation(GO:0033128)
0.1 0.6 GO:0034145 positive regulation of toll-like receptor 4 signaling pathway(GO:0034145)
0.1 1.5 GO:0045793 positive regulation of cell size(GO:0045793)
0.1 0.4 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.1 0.5 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 0.4 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.4 GO:0035754 B cell chemotaxis(GO:0035754)
0.0 0.7 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.2 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0 0.5 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.3 GO:0009301 snRNA transcription(GO:0009301)
0.0 2.7 GO:0070527 platelet aggregation(GO:0070527)
0.0 0.4 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.4 GO:0009143 nucleoside triphosphate catabolic process(GO:0009143)
0.0 0.3 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.0 0.1 GO:0098928 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.0 1.9 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.9 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 1.8 GO:0002066 columnar/cuboidal epithelial cell development(GO:0002066)
0.0 0.7 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 0.0 GO:0001920 negative regulation of receptor recycling(GO:0001920)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 0.9 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 1.9 GO:0001772 immunological synapse(GO:0001772)
0.0 0.2 GO:0001740 Barr body(GO:0001740)
0.0 0.4 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.1 GO:0099569 presynaptic cytoskeleton(GO:0099569)
0.0 0.3 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.7 GO:0005882 intermediate filament(GO:0005882)
0.0 2.1 GO:0044798 nuclear transcription factor complex(GO:0044798)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0070330 aromatase activity(GO:0070330)
0.1 0.5 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
0.1 0.4 GO:0004528 phosphodiesterase I activity(GO:0004528) NADH pyrophosphatase activity(GO:0035529)
0.1 0.7 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 1.1 GO:0035198 miRNA binding(GO:0035198)
0.1 0.4 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.9 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.2 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.0 0.9 GO:0031402 sodium ion binding(GO:0031402)
0.0 0.2 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.0 7.4 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 1.6 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.5 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 1.3 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 1.9 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.0 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.0 0.3 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 REACTOME_REGULATION_OF_KIT_SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.4 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.6 REACTOME_IRAK1_RECRUITS_IKK_COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.9 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.0 0.5 REACTOME_GLYCOSPHINGOLIPID_METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.3 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.0 0.3 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.9 REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES Genes involved in Antiviral mechanism by IFN-stimulated genes