Motif ID: Sox6_Sox9

Z-value: 0.877

Transcription factors associated with Sox6_Sox9:

Gene SymbolEntrez IDGene Name
Sox6 ENSMUSG00000051910.7 Sox6
Sox9 ENSMUSG00000000567.5 Sox9

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sox9mm10_v2_chr11_+_112782182_1127822480.342.6e-03Click!
Sox6mm10_v2_chr7_-_116038734_1160387500.066.0e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Sox6_Sox9

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_-_106715251 11.994 ENSMUST00000080853.4
ENSMUST00000183610.1
ENSMUST00000103069.3
ENSMUST00000106796.2
Pecam1



platelet/endothelial cell adhesion molecule 1



chr13_-_97747373 7.580 ENSMUST00000123535.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr13_-_97747399 7.356 ENSMUST00000144993.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr8_-_11312731 6.223 ENSMUST00000033898.9
Col4a1
collagen, type IV, alpha 1
chr8_-_84773381 5.927 ENSMUST00000109764.1
Nfix
nuclear factor I/X
chr6_+_17463749 5.772 ENSMUST00000115443.1
Met
met proto-oncogene
chr9_-_79718631 5.288 ENSMUST00000180083.1
Col12a1
collagen, type XII, alpha 1
chr9_-_79718518 4.867 ENSMUST00000071750.6
Col12a1
collagen, type XII, alpha 1
chr11_-_114795888 4.838 ENSMUST00000000206.3
Btbd17
BTB (POZ) domain containing 17
chr15_-_91049823 4.789 ENSMUST00000088614.5
ENSMUST00000100304.4
ENSMUST00000067205.8
ENSMUST00000109288.2
ENSMUST00000109287.2
Kif21a




kinesin family member 21A




chr1_-_155146755 4.593 ENSMUST00000027744.8
Mr1
major histocompatibility complex, class I-related
chr9_-_79718720 4.488 ENSMUST00000121227.1
Col12a1
collagen, type XII, alpha 1
chr2_+_180598219 4.470 ENSMUST00000103059.1
Col9a3
collagen, type IX, alpha 3
chr12_-_34528844 4.445 ENSMUST00000110819.2
Hdac9
histone deacetylase 9
chr3_+_34649987 4.422 ENSMUST00000099151.2
Sox2
SRY-box containing gene 2
chr12_+_119945957 4.396 ENSMUST00000058644.8
Tmem196
transmembrane protein 196
chr2_+_146221921 4.378 ENSMUST00000089257.4
Insm1
insulinoma-associated 1
chr5_+_3344194 4.355 ENSMUST00000042410.4
Cdk6
cyclin-dependent kinase 6
chr1_-_72874877 4.339 ENSMUST00000027377.8
Igfbp5
insulin-like growth factor binding protein 5
chr6_+_86404219 4.074 ENSMUST00000095754.3
ENSMUST00000095753.2
Tia1

cytotoxic granule-associated RNA binding protein 1

chr1_+_135729147 3.968 ENSMUST00000027677.7
Csrp1
cysteine and glycine-rich protein 1
chr3_-_10208569 3.935 ENSMUST00000029041.4
Fabp4
fatty acid binding protein 4, adipocyte
chr6_+_86404257 3.914 ENSMUST00000095752.2
ENSMUST00000130967.1
Tia1

cytotoxic granule-associated RNA binding protein 1

chr9_-_32541589 3.866 ENSMUST00000016231.7
Fli1
Friend leukemia integration 1
chr5_+_66968416 3.835 ENSMUST00000038188.7
Limch1
LIM and calponin homology domains 1
chr8_+_11312805 3.832 ENSMUST00000033899.7
Col4a2
collagen, type IV, alpha 2
chr6_+_86404336 3.735 ENSMUST00000113713.2
ENSMUST00000113708.1
Tia1

cytotoxic granule-associated RNA binding protein 1

chr9_-_72111651 3.702 ENSMUST00000185117.1
Tcf12
transcription factor 12
chr12_+_29528382 3.694 ENSMUST00000049784.9
Myt1l
myelin transcription factor 1-like
chr6_+_65671590 3.662 ENSMUST00000054351.4
Ndnf
neuron-derived neurotrophic factor
chr17_-_68004075 3.651 ENSMUST00000024840.5
Arhgap28
Rho GTPase activating protein 28
chr5_+_3343893 3.640 ENSMUST00000165117.1
Cdk6
cyclin-dependent kinase 6
chr18_+_37484955 3.535 ENSMUST00000053856.4
Pcdhb17
protocadherin beta 17
chr8_+_25518757 3.449 ENSMUST00000178276.1
ENSMUST00000179592.1
Fgfr1

fibroblast growth factor receptor 1

chr5_+_66968559 3.380 ENSMUST00000127184.1
Limch1
LIM and calponin homology domains 1
chr8_+_25518783 3.371 ENSMUST00000084027.5
ENSMUST00000117179.2
Fgfr1

fibroblast growth factor receptor 1

chr6_+_17463826 3.323 ENSMUST00000140070.1
Met
met proto-oncogene
chrX_-_18461371 3.310 ENSMUST00000044188.4
4930578C19Rik
RIKEN cDNA 4930578C19 gene
chr2_+_4400958 3.181 ENSMUST00000075767.7
Frmd4a
FERM domain containing 4A
chr12_-_119238794 3.089 ENSMUST00000026360.8
Itgb8
integrin beta 8
chr2_-_160367057 3.033 ENSMUST00000099126.3
Mafb
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)
chr3_-_116129615 2.988 ENSMUST00000029574.8
Vcam1
vascular cell adhesion molecule 1
chr6_+_125552948 2.937 ENSMUST00000112254.1
ENSMUST00000112253.1
ENSMUST00000001995.7
Vwf


Von Willebrand factor homolog


chr15_+_75596645 2.865 ENSMUST00000023243.4
Gpihbp1
GPI-anchored HDL-binding protein 1
chr15_+_6386598 2.844 ENSMUST00000080880.5
ENSMUST00000110664.2
ENSMUST00000110663.2
ENSMUST00000161812.1
ENSMUST00000160134.1
Dab2




disabled 2, mitogen-responsive phosphoprotein




chr13_-_41358990 2.771 ENSMUST00000163623.1
Nedd9
neural precursor cell expressed, developmentally down-regulated gene 9
chr10_-_83534130 2.751 ENSMUST00000020497.7
Aldh1l2
aldehyde dehydrogenase 1 family, member L2
chr2_-_33942111 2.723 ENSMUST00000130988.1
ENSMUST00000127936.1
ENSMUST00000134271.1
Gm13403


predicted gene 13403


chr6_+_34598530 2.687 ENSMUST00000115027.1
ENSMUST00000115026.1
Cald1

caldesmon 1

chr10_-_30655859 2.555 ENSMUST00000092610.4
Ncoa7
nuclear receptor coactivator 7
chr5_-_105343929 2.550 ENSMUST00000183149.1
Gbp11
guanylate binding protein 11
chr11_+_94044194 2.458 ENSMUST00000092777.4
ENSMUST00000075695.6
Spag9

sperm associated antigen 9

chr1_-_56972437 2.427 ENSMUST00000042857.7
Satb2
special AT-rich sequence binding protein 2
chr11_+_94044241 2.421 ENSMUST00000103168.3
Spag9
sperm associated antigen 9
chr15_+_25622525 2.418 ENSMUST00000110457.1
ENSMUST00000137601.1
Myo10

myosin X

chr6_+_53573364 2.404 ENSMUST00000047450.7
Creb5
cAMP responsive element binding protein 5
chr9_+_27790947 2.372 ENSMUST00000115243.2
Opcml
opioid binding protein/cell adhesion molecule-like
chr3_+_90541146 2.344 ENSMUST00000107333.1
ENSMUST00000107331.1
ENSMUST00000098910.2
S100a16


S100 calcium binding protein A16


chr18_-_23038656 2.312 ENSMUST00000081423.6
Nol4
nucleolar protein 4
chr2_+_25180737 2.274 ENSMUST00000104999.2
Nrarp
Notch-regulated ankyrin repeat protein
chr15_-_88978958 2.245 ENSMUST00000042594.6
ENSMUST00000109368.1
Mlc1

megalencephalic leukoencephalopathy with subcortical cysts 1 homolog (human)

chr9_-_72111172 2.183 ENSMUST00000183992.1
Tcf12
transcription factor 12
chr10_-_62792243 2.160 ENSMUST00000020268.5
Ccar1
cell division cycle and apoptosis regulator 1
chr12_-_58269162 2.156 ENSMUST00000062254.2
Clec14a
C-type lectin domain family 14, member a
chr4_-_118490030 2.119 ENSMUST00000047421.5
Tie1
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr1_+_59482133 2.086 ENSMUST00000114246.2
ENSMUST00000037105.6
Fzd7

frizzled homolog 7 (Drosophila)

chr7_-_126676357 2.072 ENSMUST00000106371.1
ENSMUST00000106372.3
ENSMUST00000155419.1
Sult1a1


sulfotransferase family 1A, phenol-preferring, member 1


chr14_-_118052235 2.028 ENSMUST00000022725.2
Dct
dopachrome tautomerase
chr6_+_34598500 2.028 ENSMUST00000079391.3
ENSMUST00000142512.1
Cald1

caldesmon 1

chr6_-_31563978 1.990 ENSMUST00000026698.7
Podxl
podocalyxin-like
chr14_-_68655804 1.972 ENSMUST00000111072.1
ENSMUST00000022642.5
Adam28

a disintegrin and metallopeptidase domain 28

chr5_-_17835857 1.915 ENSMUST00000082367.6
Cd36
CD36 antigen
chr6_-_12749193 1.906 ENSMUST00000046121.6
ENSMUST00000172356.1
Thsd7a

thrombospondin, type I, domain containing 7A

chr11_+_88068242 1.904 ENSMUST00000018521.4
Vezf1
vascular endothelial zinc finger 1
chr17_-_24644933 1.883 ENSMUST00000019684.5
Slc9a3r2
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
chr6_+_17463927 1.879 ENSMUST00000115442.1
Met
met proto-oncogene
chr10_-_17947997 1.879 ENSMUST00000037879.6
Heca
headcase homolog (Drosophila)
chr8_-_71395794 1.867 ENSMUST00000049184.7
Ushbp1
Usher syndrome 1C binding protein 1
chr13_+_75967704 1.819 ENSMUST00000022081.1
Spata9
spermatogenesis associated 9
chr7_-_103813913 1.758 ENSMUST00000098192.3
Hbb-bt
hemoglobin, beta adult t chain
chr7_-_126676428 1.756 ENSMUST00000106373.1
Sult1a1
sulfotransferase family 1A, phenol-preferring, member 1
chr4_+_122995944 1.730 ENSMUST00000106252.2
Mycl
v-myc myelocytomatosis viral oncogene homolog, lung carcinoma derived (avian)
chr4_+_94739276 1.692 ENSMUST00000073939.6
ENSMUST00000102798.1
Tek

endothelial-specific receptor tyrosine kinase

chr5_+_48242549 1.674 ENSMUST00000172493.1
Slit2
slit homolog 2 (Drosophila)
chrX_+_77511002 1.667 ENSMUST00000088217.5
Tbl1x
transducin (beta)-like 1 X-linked
chr14_-_16575456 1.639 ENSMUST00000063750.6
Rarb
retinoic acid receptor, beta
chr4_+_122996035 1.632 ENSMUST00000030407.7
Mycl
v-myc myelocytomatosis viral oncogene homolog, lung carcinoma derived (avian)
chrX_+_136822671 1.625 ENSMUST00000033800.6
Plp1
proteolipid protein (myelin) 1
chr10_+_67096456 1.609 ENSMUST00000174317.1
Jmjd1c
jumonji domain containing 1C
chr2_+_105682463 1.595 ENSMUST00000140173.1
ENSMUST00000135412.1
ENSMUST00000138365.1
ENSMUST00000145744.1
Pax6



paired box gene 6



chr18_+_65698253 1.578 ENSMUST00000115097.1
ENSMUST00000117694.1
Oacyl

O-acyltransferase like

chr18_+_37477768 1.566 ENSMUST00000051442.5
Pcdhb16
protocadherin beta 16
chr5_+_109996506 1.540 ENSMUST00000112540.1
ENSMUST00000099484.2
ENSMUST00000125213.1
ENSMUST00000143639.1
Zfp932



zinc finger protein 932



chr7_+_96210107 1.528 ENSMUST00000138760.1
Tenm4
teneurin transmembrane protein 4
chr4_+_148130883 1.508 ENSMUST00000084129.2
Mad2l2
MAD2 mitotic arrest deficient-like 2
chr4_-_118489755 1.504 ENSMUST00000184261.1
Tie1
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr18_-_15063560 1.502 ENSMUST00000168989.1
Kctd1
potassium channel tetramerisation domain containing 1
chr4_+_48585135 1.484 ENSMUST00000030032.6
Tmeff1
transmembrane protein with EGF-like and two follistatin-like domains 1
chr2_+_4559742 1.423 ENSMUST00000176828.1
Frmd4a
FERM domain containing 4A
chr1_-_119837613 1.417 ENSMUST00000064091.5
Ptpn4
protein tyrosine phosphatase, non-receptor type 4
chr3_-_95891938 1.415 ENSMUST00000036360.6
ENSMUST00000090476.3
BC028528

cDNA sequence BC028528

chr10_-_58675631 1.414 ENSMUST00000003312.4
Edar
ectodysplasin-A receptor
chr6_+_83137089 1.387 ENSMUST00000121093.1
ENSMUST00000087938.4
Rtkn

rhotekin

chrX_+_112600526 1.379 ENSMUST00000113409.1
Zfp711
zinc finger protein 711
chr2_+_3713478 1.340 ENSMUST00000115053.2
Fam107b
family with sequence similarity 107, member B
chr10_+_29143996 1.338 ENSMUST00000092629.2
Soga3
SOGA family member 3
chr2_+_102658640 1.333 ENSMUST00000080210.3
Slc1a2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr2_-_20968526 1.330 ENSMUST00000141298.2
ENSMUST00000125783.2
Arhgap21

Rho GTPase activating protein 21

chr1_+_160906372 1.326 ENSMUST00000161609.1
Rc3h1
RING CCCH (C3H) domains 1
chr4_-_34882919 1.326 ENSMUST00000098163.2
ENSMUST00000047950.5
Zfp292

zinc finger protein 292

chr1_+_75546449 1.314 ENSMUST00000150142.1
Slc4a3
solute carrier family 4 (anion exchanger), member 3
chr11_+_87581041 1.313 ENSMUST00000018544.5
ENSMUST00000063156.4
ENSMUST00000107960.1
Sept4


septin 4


chr7_-_142666816 1.309 ENSMUST00000105935.1
Igf2
insulin-like growth factor 2
chr5_+_109923400 1.307 ENSMUST00000112544.1
Gm15446
predicted gene 15446
chr19_+_55741810 1.305 ENSMUST00000111657.3
ENSMUST00000061496.9
ENSMUST00000041717.7
ENSMUST00000111662.4
Tcf7l2



transcription factor 7 like 2, T cell specific, HMG box



chr17_+_55445550 1.295 ENSMUST00000025000.3
St6gal2
beta galactoside alpha 2,6 sialyltransferase 2
chr4_+_48585276 1.278 ENSMUST00000123476.1
Tmeff1
transmembrane protein with EGF-like and two follistatin-like domains 1
chr2_+_150909565 1.272 ENSMUST00000028948.4
Gins1
GINS complex subunit 1 (Psf1 homolog)
chr18_+_11633276 1.207 ENSMUST00000115861.2
Rbbp8
retinoblastoma binding protein 8
chr3_+_135825788 1.200 ENSMUST00000167390.1
Slc39a8
solute carrier family 39 (metal ion transporter), member 8
chr5_-_109751597 1.189 ENSMUST00000112547.1
4930522L14Rik
RIKEN cDNA 4930522L14 gene
chr14_+_54431597 1.188 ENSMUST00000089688.4
Mmp14
matrix metallopeptidase 14 (membrane-inserted)
chr9_-_72111755 1.177 ENSMUST00000183492.1
ENSMUST00000184523.1
ENSMUST00000034755.6
Tcf12


transcription factor 12


chrX_+_57053549 1.175 ENSMUST00000114751.2
ENSMUST00000088652.5
Htatsf1

HIV TAT specific factor 1

chr1_-_119837338 1.164 ENSMUST00000163435.1
Ptpn4
protein tyrosine phosphatase, non-receptor type 4
chr12_+_29938036 1.145 ENSMUST00000122328.1
ENSMUST00000118321.1
Pxdn

peroxidasin homolog (Drosophila)

chr7_-_132813095 1.143 ENSMUST00000106165.1
Fam53b
family with sequence similarity 53, member B
chr11_+_61653259 1.139 ENSMUST00000004959.2
Grap
GRB2-related adaptor protein
chr16_+_17276662 1.121 ENSMUST00000069420.4
Tmem191c
transmembrane protein 191C
chr4_+_108460000 1.121 ENSMUST00000097925.2
Zcchc11
zinc finger, CCHC domain containing 11
chr13_-_106847267 1.119 ENSMUST00000057427.4
Lrrc70
leucine rich repeat containing 70
chr2_-_65567465 1.115 ENSMUST00000066432.5
Scn3a
sodium channel, voltage-gated, type III, alpha
chr18_+_37307445 1.105 ENSMUST00000056712.2
Pcdhb4
protocadherin beta 4
chr10_-_24836165 1.086 ENSMUST00000020169.7
Enpp3
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr11_+_94044331 1.076 ENSMUST00000024979.8
Spag9
sperm associated antigen 9
chr4_+_137993445 1.075 ENSMUST00000105831.2
ENSMUST00000084214.5
Eif4g3

eukaryotic translation initiation factor 4 gamma, 3

chrX_-_16911774 1.073 ENSMUST00000040134.7
Ndp
Norrie disease (pseudoglioma) (human)
chr7_-_132813528 1.062 ENSMUST00000097999.2
Fam53b
family with sequence similarity 53, member B
chr10_+_116301374 1.061 ENSMUST00000092167.5
Ptprb
protein tyrosine phosphatase, receptor type, B
chr16_+_94370618 1.058 ENSMUST00000117648.1
ENSMUST00000147352.1
ENSMUST00000150346.1
ENSMUST00000155692.1
ENSMUST00000153988.1
ENSMUST00000141856.1
ENSMUST00000152117.1
ENSMUST00000150097.1
ENSMUST00000122895.1
ENSMUST00000151770.1
Ttc3









tetratricopeptide repeat domain 3









chr18_+_37489465 1.056 ENSMUST00000055949.2
Pcdhb18
protocadherin beta 18
chr2_-_161109017 1.013 ENSMUST00000039782.7
ENSMUST00000134178.1
Chd6

chromodomain helicase DNA binding protein 6

chr15_-_102722120 1.004 ENSMUST00000171838.1
Calcoco1
calcium binding and coiled coil domain 1
chr1_-_119836999 0.994 ENSMUST00000163621.1
ENSMUST00000168303.1
Ptpn4

protein tyrosine phosphatase, non-receptor type 4

chr8_-_46080284 0.991 ENSMUST00000177186.1
Snx25
sorting nexin 25
chr15_-_26895049 0.986 ENSMUST00000059204.9
Fbxl7
F-box and leucine-rich repeat protein 7
chr19_-_56822161 0.979 ENSMUST00000118592.1
A630007B06Rik
RIKEN cDNA A630007B06 gene
chr13_+_21945084 0.971 ENSMUST00000176511.1
ENSMUST00000102978.1
ENSMUST00000152258.2
Zfp184


zinc finger protein 184 (Kruppel-like)


chr9_+_109095427 0.971 ENSMUST00000072093.6
Plxnb1
plexin B1
chr6_+_143167210 0.962 ENSMUST00000032413.4
Etnk1
ethanolamine kinase 1
chr16_+_4036942 0.960 ENSMUST00000137748.1
ENSMUST00000006136.4
ENSMUST00000157044.1
ENSMUST00000120009.1
Dnase1



deoxyribonuclease I



chr3_+_101377074 0.946 ENSMUST00000043983.5
Igsf3
immunoglobulin superfamily, member 3
chr4_+_137993016 0.934 ENSMUST00000105830.2
ENSMUST00000084215.5
ENSMUST00000058133.3
ENSMUST00000139759.1
Eif4g3



eukaryotic translation initiation factor 4 gamma, 3



chr15_-_102722150 0.931 ENSMUST00000023818.3
Calcoco1
calcium binding and coiled coil domain 1
chr5_+_3928267 0.930 ENSMUST00000044492.8
Akap9
A kinase (PRKA) anchor protein (yotiao) 9
chr9_+_110532501 0.922 ENSMUST00000153838.2
Setd2
SET domain containing 2
chr4_+_43875524 0.920 ENSMUST00000030198.6
Reck
reversion-inducing-cysteine-rich protein with kazal motifs
chr1_-_163289214 0.920 ENSMUST00000183691.1
Prrx1
paired related homeobox 1
chr12_+_19606929 0.915 ENSMUST00000105167.1
Gm9257
predicted gene 9257
chrX_+_166238901 0.903 ENSMUST00000112235.1
Gpm6b
glycoprotein m6b
chr2_-_146511899 0.899 ENSMUST00000131824.1
Ralgapa2
Ral GTPase activating protein, alpha subunit 2 (catalytic)
chr15_+_83779975 0.897 ENSMUST00000163723.1
Mpped1
metallophosphoesterase domain containing 1
chr3_+_31902666 0.896 ENSMUST00000119970.1
ENSMUST00000178668.1
Kcnmb2

potassium large conductance calcium-activated channel, subfamily M, beta member 2

chr11_-_6274830 0.895 ENSMUST00000132147.1
ENSMUST00000004508.6
Tmed4

transmembrane emp24 protein transport domain containing 4

chrX_-_104201126 0.884 ENSMUST00000056502.6
ENSMUST00000118314.1
C77370

expressed sequence C77370

chr3_-_66296807 0.884 ENSMUST00000029419.7
Veph1
ventricular zone expressed PH domain-containing 1
chr4_-_116405986 0.869 ENSMUST00000123072.1
ENSMUST00000144281.1
Mast2

microtubule associated serine/threonine kinase 2

chr12_+_24831583 0.868 ENSMUST00000110942.3
ENSMUST00000078902.6
Mboat2

membrane bound O-acyltransferase domain containing 2

chr11_-_49187159 0.866 ENSMUST00000046522.6
Btnl9
butyrophilin-like 9
chr4_-_91399984 0.859 ENSMUST00000102799.3
Elavl2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr4_+_11579647 0.855 ENSMUST00000180239.1
Fsbp
fibrinogen silencer binding protein
chr19_+_53600377 0.840 ENSMUST00000025930.9
Smc3
structural maintenance of chromosomes 3
chr12_+_8674129 0.839 ENSMUST00000111123.2
ENSMUST00000178015.1
ENSMUST00000020915.3
Pum2


pumilio 2 (Drosophila)


chr7_+_127800604 0.838 ENSMUST00000046863.5
ENSMUST00000106272.1
ENSMUST00000139068.1
Hsd3b7


hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7


chr6_+_86628174 0.833 ENSMUST00000043400.6
Asprv1
aspartic peptidase, retroviral-like 1
chrX_+_109095359 0.833 ENSMUST00000033598.8
Sh3bgrl
SH3-binding domain glutamic acid-rich protein like
chr2_-_104816696 0.801 ENSMUST00000117237.1
Qser1
glutamine and serine rich 1
chr6_+_48593883 0.798 ENSMUST00000154010.1
ENSMUST00000163452.1
ENSMUST00000118229.1
ENSMUST00000009420.8
Repin1



replication initiator 1



chr10_-_53647080 0.795 ENSMUST00000169866.1
Fam184a
family with sequence similarity 184, member A
chr2_-_36104060 0.794 ENSMUST00000112961.3
ENSMUST00000112966.3
Lhx6

LIM homeobox protein 6

chr7_-_105787567 0.793 ENSMUST00000144189.1
Dchs1
dachsous 1 (Drosophila)
chr6_+_48593927 0.783 ENSMUST00000135151.1
Repin1
replication initiator 1
chr1_-_150465563 0.780 ENSMUST00000164600.1
ENSMUST00000111902.2
ENSMUST00000111901.2
ENSMUST00000006171.9
Prg4



proteoglycan 4 (megakaryocyte stimulating factor, articular superficial zone protein)



chr11_+_3330781 0.775 ENSMUST00000136536.1
ENSMUST00000093399.4
Pik3ip1

phosphoinositide-3-kinase interacting protein 1

chr12_+_51348370 0.769 ENSMUST00000121521.1
G2e3
G2/M-phase specific E3 ubiquitin ligase
chr6_+_29859374 0.766 ENSMUST00000115238.3
Ahcyl2
S-adenosylhomocysteine hydrolase-like 2
chr13_+_80886095 0.761 ENSMUST00000161441.1
Arrdc3
arrestin domain containing 3
chr13_+_14063776 0.759 ENSMUST00000129488.1
ENSMUST00000110536.1
ENSMUST00000110534.1
ENSMUST00000039538.8
ENSMUST00000110533.1
Arid4b




AT rich interactive domain 4B (RBP1-like)




chr12_-_100159601 0.744 ENSMUST00000021596.7
Nrde2
nrde-2 necessary for RNA interference, domain containing
chr4_+_141242850 0.733 ENSMUST00000138096.1
ENSMUST00000006618.2
ENSMUST00000125392.1
Arhgef19


Rho guanine nucleotide exchange factor (GEF) 19


chr19_+_47579602 0.720 ENSMUST00000026043.5
Slk
STE20-like kinase
chr18_+_37447641 0.712 ENSMUST00000052387.3
Pcdhb14
protocadherin beta 14
chr5_-_138155694 0.710 ENSMUST00000132318.1
ENSMUST00000049393.8
Zfp113

zinc finger protein 113

chr5_-_109691041 0.708 ENSMUST00000092720.3
5430403G16Rik
RIKEN cDNA 5430403G16 gene
chr14_+_79515618 0.707 ENSMUST00000110835.1
Elf1
E74-like factor 1
chr12_+_8674224 0.706 ENSMUST00000111122.2
Pum2
pumilio 2 (Drosophila)
chr12_+_51348265 0.703 ENSMUST00000119211.1
G2e3
G2/M-phase specific E3 ubiquitin ligase
chr15_-_79658749 0.702 ENSMUST00000109646.2
Fam227a
family with sequence similarity 227, member A
chr2_+_91257323 0.691 ENSMUST00000111349.2
ENSMUST00000131711.1
Pacsin3

protein kinase C and casein kinase substrate in neurons 3

chr3_-_123690806 0.687 ENSMUST00000154668.1
Ndst3
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 12.0 GO:0050904 diapedesis(GO:0050904)
2.3 6.8 GO:0021837 motogenic signaling involved in postnatal olfactory bulb interneuron migration(GO:0021837) positive regulation of mitotic cell cycle DNA replication(GO:1903465)
1.8 11.0 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
1.2 11.5 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
1.1 8.0 GO:0044838 cell quiescence(GO:0044838)
1.1 4.4 GO:0003357 noradrenergic neuron differentiation(GO:0003357)
0.9 2.8 GO:0042560 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.9 3.7 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.9 6.3 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.9 6.2 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.6 1.9 GO:0070543 response to linoleic acid(GO:0070543)
0.6 4.4 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.6 2.5 GO:0010986 positive regulation of lipoprotein particle clearance(GO:0010986)
0.6 4.3 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.6 4.6 GO:0021546 rhombomere development(GO:0021546)
0.6 2.3 GO:0021847 ventricular zone neuroblast division(GO:0021847)
0.6 1.7 GO:0048014 Tie signaling pathway(GO:0048014)
0.6 1.7 GO:0021972 corticospinal neuron axon guidance through spinal cord(GO:0021972) positive regulation of negative chemotaxis(GO:0050924) induction of negative chemotaxis(GO:0050929) negative regulation of mononuclear cell migration(GO:0071676) negative regulation of retinal ganglion cell axon guidance(GO:0090260)
0.5 1.1 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.5 2.1 GO:2000383 regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.5 5.0 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.5 2.8 GO:0032346 positive regulation of aldosterone metabolic process(GO:0032346) positive regulation of aldosterone biosynthetic process(GO:0032349) leading edge cell differentiation(GO:0035026) regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.4 3.7 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800) vascular wound healing(GO:0061042)
0.4 3.9 GO:0071285 cellular response to lithium ion(GO:0071285)
0.4 1.5 GO:0032289 central nervous system myelin formation(GO:0032289) cardiac cell fate specification(GO:0060912)
0.4 1.5 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.3 3.8 GO:0051923 sulfation(GO:0051923)
0.3 6.1 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.3 1.7 GO:0046684 response to pyrethroid(GO:0046684)
0.3 0.9 GO:0035441 cell migration involved in vasculogenesis(GO:0035441)
0.3 3.4 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.3 1.8 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.3 3.0 GO:0061032 visceral serous pericardium development(GO:0061032)
0.3 0.6 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.3 2.0 GO:0060903 positive regulation of meiosis I(GO:0060903)
0.3 1.7 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.3 2.3 GO:0014807 regulation of somitogenesis(GO:0014807)
0.3 1.6 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.3 1.3 GO:0051684 maintenance of Golgi location(GO:0051684)
0.3 2.0 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.3 1.8 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.3 0.8 GO:0090327 negative regulation of locomotion involved in locomotory behavior(GO:0090327)
0.3 1.0 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.3 1.8 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.2 2.2 GO:0047484 regulation of response to osmotic stress(GO:0047484) cellular response to cholesterol(GO:0071397)
0.2 2.4 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.2 1.0 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.2 2.9 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.2 1.2 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.2 3.8 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.2 0.6 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
0.2 4.6 GO:0032620 interleukin-17 production(GO:0032620)
0.2 0.6 GO:0043379 memory T cell differentiation(GO:0043379) negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.2 0.8 GO:0003192 mitral valve formation(GO:0003192) cell migration involved in endocardial cushion formation(GO:0003273) condensed mesenchymal cell proliferation(GO:0072137)
0.2 0.8 GO:0045409 negative regulation of interleukin-6 biosynthetic process(GO:0045409)
0.2 3.1 GO:0001573 ganglioside metabolic process(GO:0001573)
0.2 1.3 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.2 0.9 GO:0032808 lacrimal gland development(GO:0032808)
0.2 1.3 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.2 1.3 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.2 0.9 GO:1904684 negative regulation of metalloendopeptidase activity(GO:1904684)
0.2 1.3 GO:1902969 mitotic DNA replication(GO:1902969)
0.2 0.9 GO:0060178 regulation of exocyst localization(GO:0060178)
0.2 4.0 GO:0035855 megakaryocyte development(GO:0035855)
0.2 1.2 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.2 0.5 GO:0033629 negative regulation of cell adhesion mediated by integrin(GO:0033629) negative regulation of protein glycosylation in Golgi(GO:0090285)
0.2 1.3 GO:0048625 myoblast fate commitment(GO:0048625)
0.2 1.0 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.2 0.8 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.2 0.5 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.2 1.1 GO:0033484 nitric oxide homeostasis(GO:0033484)
0.1 0.9 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.1 0.7 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 1.2 GO:0045579 positive regulation of B cell differentiation(GO:0045579)
0.1 3.6 GO:0045026 plasma membrane fusion(GO:0045026)
0.1 0.9 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1 0.8 GO:0034773 histone H4-K20 trimethylation(GO:0034773) establishment of Sertoli cell barrier(GO:0097368)
0.1 0.3 GO:0090649 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.1 1.1 GO:0010587 miRNA catabolic process(GO:0010587)
0.1 1.2 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.1 0.8 GO:0035754 B cell chemotaxis(GO:0035754)
0.1 4.6 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 0.8 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.1 0.9 GO:0045075 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.1 1.6 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.1 1.9 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 0.8 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.1 0.8 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.1 0.5 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.1 0.9 GO:0048664 neuron fate determination(GO:0048664)
0.1 1.1 GO:0009143 nucleoside triphosphate catabolic process(GO:0009143)
0.1 4.8 GO:0006940 regulation of smooth muscle contraction(GO:0006940)
0.1 1.3 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.1 0.4 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.1 1.2 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.1 4.0 GO:0070527 platelet aggregation(GO:0070527)
0.1 1.6 GO:2001273 regulation of glucose import in response to insulin stimulus(GO:2001273)
0.1 1.0 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1 2.2 GO:0035411 catenin import into nucleus(GO:0035411)
0.1 0.4 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.1 0.3 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.1 1.1 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.1 0.2 GO:1902527 positive regulation of protein K48-linked ubiquitination(GO:1902524) positive regulation of protein monoubiquitination(GO:1902527)
0.1 2.2 GO:0002042 cell migration involved in sprouting angiogenesis(GO:0002042)
0.1 0.3 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.1 0.7 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1 0.1 GO:1901079 relaxation of smooth muscle(GO:0044557) positive regulation of relaxation of muscle(GO:1901079)
0.1 0.7 GO:0016246 RNA interference(GO:0016246)
0.1 0.5 GO:0006895 Golgi to endosome transport(GO:0006895)
0.1 0.7 GO:0033129 positive regulation of histone phosphorylation(GO:0033129)
0.1 0.6 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.5 GO:0070307 lens fiber cell development(GO:0070307)
0.0 1.0 GO:0006308 DNA catabolic process(GO:0006308)
0.0 0.7 GO:0046688 response to copper ion(GO:0046688)
0.0 6.5 GO:0007416 synapse assembly(GO:0007416)
0.0 1.3 GO:0030168 platelet activation(GO:0030168)
0.0 0.6 GO:0048813 dendrite morphogenesis(GO:0048813)
0.0 0.2 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.1 GO:0098968 neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968)
0.0 0.7 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.5 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.1 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.0 1.1 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 3.0 GO:0008584 male gonad development(GO:0008584) development of primary male sexual characteristics(GO:0046546)
0.0 0.6 GO:0001516 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.0 0.3 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.0 0.5 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.2 GO:0050912 detection of chemical stimulus involved in sensory perception(GO:0050907) detection of chemical stimulus involved in sensory perception of taste(GO:0050912)
0.0 1.0 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.5 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.0 0.6 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 0.6 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 1.2 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.2 GO:0035826 hypotonic response(GO:0006971) rubidium ion transport(GO:0035826) cellular hypotonic response(GO:0071476)
0.0 0.3 GO:0070842 aggresome assembly(GO:0070842)
0.0 0.0 GO:0003162 atrioventricular node development(GO:0003162)
0.0 0.2 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.0 0.3 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.4 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.0 0.9 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 3.6 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 2.4 GO:0007605 sensory perception of sound(GO:0007605)
0.0 0.3 GO:0048368 lateral mesoderm development(GO:0048368)
0.0 0.1 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.0 1.3 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.0 GO:2000790 regulation of mesenchymal cell proliferation involved in lung development(GO:2000790) negative regulation of mesenchymal cell proliferation involved in lung development(GO:2000791)
0.0 4.4 GO:0007018 microtubule-based movement(GO:0007018)
0.0 1.5 GO:2001243 negative regulation of intrinsic apoptotic signaling pathway(GO:2001243)
0.0 0.1 GO:0002087 regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.0 0.1 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.0 0.4 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.0 0.4 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.1 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.0 0.4 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.1 GO:1900095 regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.0 0.8 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.2 GO:0042993 positive regulation of transcription factor import into nucleus(GO:0042993)
0.0 0.4 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.0 0.0 GO:2000616 negative regulation of histone H3-K9 acetylation(GO:2000616)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
4.9 14.6 GO:0030934 collagen type XII trimer(GO:0005595) anchoring collagen complex(GO:0030934)
2.4 12.0 GO:0030485 smooth muscle contractile fiber(GO:0030485)
2.0 10.1 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
1.3 11.5 GO:0097165 nuclear stress granule(GO:0097165)
1.1 4.5 GO:0005593 FACIT collagen trimer(GO:0005593)
1.1 4.3 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.7 2.8 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.6 2.9 GO:0033093 Weibel-Palade body(GO:0033093)
0.5 4.7 GO:0030478 actin cap(GO:0030478)
0.4 1.8 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.4 1.3 GO:0000811 GINS complex(GO:0000811)
0.4 2.4 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.4 4.6 GO:0042612 MHC class I protein complex(GO:0042612)
0.3 1.2 GO:0044307 dendritic branch(GO:0044307)
0.2 2.2 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.2 0.8 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.2 1.2 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.2 2.9 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 1.3 GO:0097227 sperm annulus(GO:0097227)
0.1 1.3 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.1 3.1 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.1 9.1 GO:0009925 basal plasma membrane(GO:0009925)
0.1 7.8 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 0.7 GO:0042382 paraspeckles(GO:0042382)
0.1 0.3 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.1 0.6 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 1.7 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 5.8 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 2.0 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 5.1 GO:0005871 kinesin complex(GO:0005871)
0.1 8.2 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 0.6 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 1.2 GO:0005686 U2 snRNP(GO:0005686)
0.1 1.0 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 2.1 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 1.6 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 2.4 GO:0016459 myosin complex(GO:0016459)
0.0 5.2 GO:0005923 bicellular tight junction(GO:0005923)
0.0 7.6 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.0 0.4 GO:0005916 fascia adherens(GO:0005916)
0.0 3.8 GO:0005901 caveola(GO:0005901)
0.0 2.8 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.5 GO:0036038 MKS complex(GO:0036038)
0.0 0.2 GO:0072487 MSL complex(GO:0072487)
0.0 0.9 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.3 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 1.2 GO:0032420 stereocilium(GO:0032420)
0.0 1.2 GO:0002102 podosome(GO:0002102)
0.0 2.2 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.4 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.3 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.0 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 1.6 GO:0005811 lipid particle(GO:0005811)
0.0 6.0 GO:0043235 receptor complex(GO:0043235)
0.0 0.5 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.7 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 2.6 GO:0000922 spindle pole(GO:0000922)
0.0 1.0 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.5 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 1.2 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 3.5 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.8 GO:0005657 replication fork(GO:0005657)
0.0 0.5 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.1 GO:0005641 nuclear envelope lumen(GO:0005641)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 11.0 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
2.7 8.2 GO:0098770 FBXO family protein binding(GO:0098770)
1.3 3.8 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.9 2.8 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.8 7.1 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.7 5.2 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.7 3.0 GO:0008131 primary amine oxidase activity(GO:0008131)
0.7 2.9 GO:0035473 lipase binding(GO:0035473)
0.6 1.9 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.5 4.3 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.5 3.6 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.4 1.8 GO:0031721 haptoglobin binding(GO:0031720) hemoglobin alpha binding(GO:0031721)
0.4 6.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.4 6.1 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.4 1.9 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.4 3.1 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.4 7.1 GO:0035497 cAMP response element binding(GO:0035497)
0.3 11.7 GO:0017091 AU-rich element binding(GO:0017091)
0.3 1.8 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.3 2.9 GO:0019865 immunoglobulin binding(GO:0019865)
0.3 2.0 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.3 3.7 GO:0050897 cobalt ion binding(GO:0050897)
0.3 1.1 GO:0004528 phosphodiesterase I activity(GO:0004528) NADH pyrophosphatase activity(GO:0035529)
0.3 0.8 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.2 4.4 GO:0035198 miRNA binding(GO:0035198)
0.2 1.1 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.2 2.8 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.2 0.8 GO:0036033 mediator complex binding(GO:0036033)
0.2 0.8 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.2 4.4 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.2 1.0 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.2 0.6 GO:0046969 histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.2 0.7 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.2 0.5 GO:0071633 dihydroceramidase activity(GO:0071633)
0.2 2.0 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.2 0.9 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1 0.9 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.1 0.6 GO:0004667 prostaglandin-D synthase activity(GO:0004667) prostaglandin-E synthase activity(GO:0050220)
0.1 0.6 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.1 3.8 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 0.3 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 1.6 GO:0003680 AT DNA binding(GO:0003680)
0.1 1.0 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.1 6.1 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 0.4 GO:0036468 aromatic-L-amino-acid decarboxylase activity(GO:0004058) L-dopa decarboxylase activity(GO:0036468)
0.1 1.6 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 0.5 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 4.1 GO:0030332 cyclin binding(GO:0030332)
0.1 5.3 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.1 2.1 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 1.6 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 1.0 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 0.4 GO:0034046 poly(G) binding(GO:0034046)
0.1 1.2 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.1 1.2 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 2.9 GO:0005504 fatty acid binding(GO:0005504)
0.1 1.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 0.5 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.1 1.1 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.1 1.0 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.1 5.1 GO:0003777 microtubule motor activity(GO:0003777)
0.1 1.6 GO:0005248 voltage-gated sodium channel activity(GO:0005248)
0.1 0.6 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.1 1.9 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.1 1.2 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 0.7 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.1 0.6 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 0.2 GO:0008527 taste receptor activity(GO:0008527)
0.1 1.3 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.9 GO:0071837 HMG box domain binding(GO:0071837)
0.0 3.1 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.8 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 1.2 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.6 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 1.5 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 8.0 GO:0019903 protein phosphatase binding(GO:0019903)
0.0 2.4 GO:0003774 motor activity(GO:0003774)
0.0 0.8 GO:0031690 adrenergic receptor binding(GO:0031690)
0.0 0.2 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.1 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.0 0.2 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 0.1 GO:0043426 MRF binding(GO:0043426)
0.0 2.6 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 2.0 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 1.5 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.4 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 1.1 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.3 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.2 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.3 GO:0004707 MAP kinase activity(GO:0004707)
0.0 1.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.5 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 1.0 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.4 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 1.1 GO:0019902 phosphatase binding(GO:0019902)
0.0 0.6 GO:0004713 protein tyrosine kinase activity(GO:0004713)
0.0 0.3 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.0 1.4 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 2.2 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.1 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 1.5 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.3 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.4 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 1.1 GO:0005125 cytokine activity(GO:0005125)
0.0 0.7 GO:0030295 protein kinase activator activity(GO:0030295)
0.0 0.1 GO:0004111 creatine kinase activity(GO:0004111)
0.0 1.0 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.0 0.2 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.8 GO:0005178 integrin binding(GO:0005178)
0.0 0.4 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 36.3 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events
0.4 6.9 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.4 10.8 PID_INTEGRIN3_PATHWAY Beta3 integrin cell surface interactions
0.3 8.9 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.3 3.8 NABA_COLLAGENS Genes encoding collagen proteins
0.2 7.8 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.1 2.3 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.1 5.9 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events
0.1 1.7 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.1 5.0 PID_HDAC_CLASSII_PATHWAY Signaling events mediated by HDAC Class II
0.1 5.2 PID_AP1_PATHWAY AP-1 transcription factor network
0.1 2.0 PID_INTEGRIN_A4B1_PATHWAY Alpha4 beta1 integrin signaling events
0.1 2.4 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.1 4.0 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.1 1.6 PID_ANGIOPOIETIN_RECEPTOR_PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.1 1.9 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 1.6 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.9 PID_ATM_PATHWAY ATM pathway
0.0 5.7 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.4 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 3.1 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.5 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.0 1.6 PID_CDC42_PATHWAY CDC42 signaling events
0.0 0.5 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.0 0.8 NABA_CORE_MATRISOME Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.0 0.9 PID_TGFBR_PATHWAY TGF-beta receptor signaling
0.0 0.9 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.0 0.4 PID_ARF6_PATHWAY Arf6 signaling events
0.0 0.3 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 2.3 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 12.0 REACTOME_PECAM1_INTERACTIONS Genes involved in PECAM1 interactions
0.7 6.8 REACTOME_SIGNALING_BY_ACTIVATED_POINT_MUTANTS_OF_FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.5 3.8 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.5 29.2 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.4 2.9 REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.4 5.6 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.3 11.9 REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING Genes involved in Sema4D in semaphorin signaling
0.2 6.0 REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT Genes involved in Regulation of beta-cell development
0.2 3.9 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.2 7.6 REACTOME_G1_PHASE Genes involved in G1 Phase
0.2 3.5 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 2.8 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.1 4.0 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 1.7 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.1 0.8 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 6.2 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 1.2 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.1 1.0 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.1 1.3 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.1 0.5 REACTOME_SIGNALING_BY_SCF_KIT Genes involved in Signaling by SCF-KIT
0.1 1.2 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.1 1.6 REACTOME_RAS_ACTIVATION_UOPN_CA2_INFUX_THROUGH_NMDA_RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.1 0.6 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 0.2 REACTOME_FGFR2C_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.1 0.9 REACTOME_ACYL_CHAIN_REMODELLING_OF_PC Genes involved in Acyl chain remodelling of PC
0.1 0.2 REACTOME_ARMS_MEDIATED_ACTIVATION Genes involved in ARMS-mediated activation
0.1 2.0 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.1 2.4 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.1 1.1 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.0 1.9 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.4 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.0 1.8 REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.5 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 1.9 REACTOME_ANTIGEN_PROCESSING_CROSS_PRESENTATION Genes involved in Antigen processing-Cross presentation
0.0 0.3 REACTOME_GAP_JUNCTION_TRAFFICKING Genes involved in Gap junction trafficking
0.0 0.3 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 2.1 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 2.0 REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 1.6 REACTOME_MEIOTIC_RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.8 REACTOME_MEIOSIS Genes involved in Meiosis
0.0 0.7 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.2 REACTOME_CALNEXIN_CALRETICULIN_CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.5 REACTOME_RNA_POL_III_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 1.5 REACTOME_DNA_REPAIR Genes involved in DNA Repair
0.0 0.7 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.3 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.2 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.5 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.8 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase