Motif ID: Sox7

Z-value: 0.628


Transcription factors associated with Sox7:

Gene SymbolEntrez IDGene Name
Sox7 ENSMUSG00000063060.5 Sox7

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sox7mm10_v2_chr14_+_63943666_639436870.225.1e-02Click!


Activity profile for motif Sox7.

activity profile for motif Sox7


Sorted Z-values histogram for motif Sox7

Sorted Z-values for motif Sox7



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox7

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_+_103422010 25.506 ENSMUST00000182089.1
 Gm26992
predicted gene, 26992
chr2_-_93452679 6.130 ENSMUST00000111257.1
ENSMUST00000145553.1
 Cd82

CD82 antigen

chr19_+_26623419 4.893 ENSMUST00000176584.1
 Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr15_+_21111452 4.338 ENSMUST00000075132.6
 Cdh12
cadherin 12
chr7_+_78578830 3.127 ENSMUST00000064591.4
 Gm9885
predicted gene 9885
chr7_-_14562171 3.027 ENSMUST00000181796.1
 Vmn1r90
vomeronasal 1 receptor 90
chr18_+_12741324 2.985 ENSMUST00000115857.2
ENSMUST00000121018.1
ENSMUST00000119108.1
 Cabyr


calcium-binding tyrosine-(Y)-phosphorylation regulated (fibrousheathin 2)


chr6_-_99266494 2.424 ENSMUST00000113326.2
 Foxp1
forkhead box P1
chr10_-_69212996 1.585 ENSMUST00000170048.1
 A930033H14Rik
RIKEN cDNA A930033H14 gene
chr16_+_91391721 1.466 ENSMUST00000160764.1
 Gm21970
predicted gene 21970
chr15_+_16778101 1.427 ENSMUST00000026432.6
 Cdh9
cadherin 9
chr5_-_107875035 1.380 ENSMUST00000138111.1
ENSMUST00000112642.1
 Evi5

ecotropic viral integration site 5

chr12_-_75735729 1.297 ENSMUST00000021450.4
 Sgpp1
sphingosine-1-phosphate phosphatase 1
chr9_-_101198999 1.259 ENSMUST00000066773.7
 Ppp2r3a
protein phosphatase 2, regulatory subunit B'', alpha
chr12_-_20900867 1.221 ENSMUST00000079237.5
 Zfp125
zinc finger protein 125
chr10_-_79614012 1.043 ENSMUST00000059699.7
ENSMUST00000178228.1
 C2cd4c

C2 calcium-dependent domain containing 4C

chr1_+_169929929 0.898 ENSMUST00000175731.1
 1700084C01Rik
RIKEN cDNA 1700084C01 gene
chr2_+_19344317 0.826 ENSMUST00000141289.1
 4930447M23Rik
RIKEN cDNA 4930447M23 gene
chr2_-_6130117 0.754 ENSMUST00000126551.1
ENSMUST00000054254.5
ENSMUST00000114942.2
 Proser2


proline and serine rich 2


chr7_-_99182681 0.722 ENSMUST00000033001.4
 Dgat2
diacylglycerol O-acyltransferase 2
chr12_+_109734969 0.722 ENSMUST00000182268.1
ENSMUST00000181543.2
ENSMUST00000183116.1
 Mirg


miRNA containing gene


chr9_+_50575273 0.686 ENSMUST00000059081.6
ENSMUST00000180021.1
 Il18

interleukin 18

chr10_+_7667503 0.531 ENSMUST00000040135.8
 Nup43
nucleoporin 43
chr9_-_36767595 0.476 ENSMUST00000120381.2
 Stt3a
STT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae)
chr3_-_86920830 0.473 ENSMUST00000029719.8
 Dclk2
doublecortin-like kinase 2
chr7_+_30650385 0.363 ENSMUST00000181529.1
 Gm26610
predicted gene, 26610
chr14_+_113314602 0.314 ENSMUST00000072359.6
 Tpm3-rs7
tropomyosin 3, related sequence 7
chr16_+_8637674 0.258 ENSMUST00000023396.9
 Pmm2
phosphomannomutase 2
chr6_+_48684570 0.206 ENSMUST00000067506.7
ENSMUST00000119575.1
ENSMUST00000114527.2
ENSMUST00000121957.1
ENSMUST00000090070.5
 Gimap4




GTPase, IMAP family member 4




chr16_-_11176270 0.165 ENSMUST00000037633.8
 Zc3h7a
zinc finger CCCH type containing 7 A

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 4.9 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.4 1.3 GO:0007525 somatic muscle development(GO:0007525)
0.3 1.3 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.2 2.4 GO:0061470 interleukin-21 production(GO:0032625) T follicular helper cell differentiation(GO:0061470) interleukin-21 secretion(GO:0072619)
0.2 0.7 GO:0032817 regulation of natural killer cell proliferation(GO:0032817) positive regulation of natural killer cell proliferation(GO:0032819)
0.2 0.5 GO:0043686 co-translational protein modification(GO:0043686)
0.2 3.0 GO:0048240 sperm capacitation(GO:0048240)
0.1 0.7 GO:0035356 cellular triglyceride homeostasis(GO:0035356)
0.1 0.3 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.1 5.8 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 3.0 GO:0007606 sensory perception of chemical stimulus(GO:0007606)
0.0 0.5 GO:0021860 pyramidal neuron development(GO:0021860)
0.0 1.4 GO:0031338 regulation of vesicle fusion(GO:0031338)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.9 GO:0071564 npBAF complex(GO:0071564)
0.2 3.0 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 1.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.5 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.5 GO:0008250 oligosaccharyltransferase complex(GO:0008250)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.2 0.7 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.1 4.9 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.5 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 1.0 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.3 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0 2.4 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 8.7 GO:0005509 calcium ion binding(GO:0005509)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.1 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.1 4.9 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.1 1.3 PID_S1P_META_PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.7 PID_ANTHRAX_PATHWAY Cellular roles of Anthrax toxin
0.0 1.4 PID_AURORA_B_PATHWAY Aurora B signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.8 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.3 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.5 REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.3 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.7 REACTOME_TRIGLYCERIDE_BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis